ADAM8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of immune response of other organism involved in symbiotic interaction (GO:007.56844346
2modulation by organism of defense response of other organism involved in symbiotic interaction (GO:07.56844346
3positive regulation by organism of defense response of other organism involved in symbiotic interact7.56844346
4modulation by symbiont of host immune response (GO:0052553)7.56844346
5positive regulation by symbiont of host defense response (GO:0052509)7.56844346
6modulation by symbiont of host defense response (GO:0052031)7.56844346
7neutrophil activation involved in immune response (GO:0002283)5.92886347
8regulation of interferon-beta biosynthetic process (GO:0045357)5.86970021
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.60951221
10macrophage activation involved in immune response (GO:0002281)5.26661256
11response to peptidoglycan (GO:0032494)5.16708227
12detection of other organism (GO:0098543)5.04283911
13response to host immune response (GO:0052572)4.99321340
14response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.99321340
15detection of bacterium (GO:0016045)4.90128856
16positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.79552839
17positive regulation of interferon-alpha production (GO:0032727)4.76720312
18positive regulation of antigen processing and presentation (GO:0002579)4.63583142
19immunoglobulin mediated immune response (GO:0016064)4.59045566
20regulation of interferon-alpha production (GO:0032647)4.58123435
21response to host (GO:0075136)4.48832336
22response to host defenses (GO:0052200)4.48832336
23response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.48832336
24regulation of B cell receptor signaling pathway (GO:0050855)4.26639615
25detection of external biotic stimulus (GO:0098581)4.21545838
26microglial cell activation (GO:0001774)4.19794857
27neutrophil mediated immunity (GO:0002446)4.17545152
28respiratory burst (GO:0045730)4.17440386
29positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.12939692
30negative regulation of lymphocyte mediated immunity (GO:0002707)4.11859208
31natural killer cell mediated immunity (GO:0002228)4.11173002
32natural killer cell mediated cytotoxicity (GO:0042267)4.11173002
33neutrophil activation (GO:0042119)4.09150601
34regulation of gamma-delta T cell activation (GO:0046643)4.09072397
35granulocyte activation (GO:0036230)4.06545110
36regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.05926849
37myeloid cell activation involved in immune response (GO:0002275)4.05322021
38response to muramyl dipeptide (GO:0032495)3.96021432
39regulation of antigen processing and presentation (GO:0002577)3.87976783
40response to interleukin-15 (GO:0070672)3.87614426
41positive regulation of gamma-delta T cell activation (GO:0046645)3.83360607
42negative regulation of leukocyte mediated immunity (GO:0002704)3.78054832
43negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.77822863
44negative regulation of cell killing (GO:0031342)3.77822863
45regulation of dendritic cell antigen processing and presentation (GO:0002604)3.75155308
46positive regulation of mast cell activation (GO:0033005)3.72145050
47detection of biotic stimulus (GO:0009595)3.69792604
48macrophage activation (GO:0042116)3.66855995
49type I interferon signaling pathway (GO:0060337)3.65373805
50cellular response to type I interferon (GO:0071357)3.65373805
51response to type I interferon (GO:0034340)3.62747651
52pinocytosis (GO:0006907)3.61988920
53negative regulation of T cell mediated immunity (GO:0002710)3.56315352
54regulation of cholesterol storage (GO:0010885)3.55322627
55cellular response to interleukin-15 (GO:0071350)3.51722171
56negative regulation of interleukin-17 production (GO:0032700)3.48113583
57regulation of gamma-delta T cell differentiation (GO:0045586)3.47421292
58regulation of mast cell degranulation (GO:0043304)3.47278591
59regulation of T cell tolerance induction (GO:0002664)3.42425135
60regulation of mast cell activation (GO:0033003)3.40498454
61B cell mediated immunity (GO:0019724)3.40095116
62positive regulation of interferon-beta production (GO:0032728)3.39273497
63negative regulation of erythrocyte differentiation (GO:0045647)3.37167393
64negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.36461115
65regulation of mononuclear cell migration (GO:0071675)3.34984851
66regulation of interleukin-8 biosynthetic process (GO:0045414)3.33695816
67B cell receptor signaling pathway (GO:0050853)3.30835947
68cellular extravasation (GO:0045123)3.28459426
69regulation of mast cell activation involved in immune response (GO:0033006)3.28296540
70regulation of tolerance induction (GO:0002643)3.28057872
71antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.24875519
72antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.24875519
73myeloid leukocyte mediated immunity (GO:0002444)3.23589832
74negative regulation of phagocytosis (GO:0050765)3.23365674
75I-kappaB phosphorylation (GO:0007252)3.23104190
76antigen processing and presentation of endogenous antigen (GO:0019883)3.20932693
77negative regulation of mast cell activation (GO:0033004)3.19405790
78leukocyte mediated cytotoxicity (GO:0001909)3.19081489
79positive regulation of B cell differentiation (GO:0045579)3.16440761
80antigen processing and presentation via MHC class Ib (GO:0002475)3.16247302
81regulation of T cell mediated cytotoxicity (GO:0001914)3.15758400
82regulation of B cell differentiation (GO:0045577)3.15288953
83negative regulation of cytokine production involved in immune response (GO:0002719)3.13322246
84positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.12003273
85negative thymic T cell selection (GO:0045060)3.10955851
86regulation of leukocyte degranulation (GO:0043300)3.10663070
87regulation of T-helper 2 cell differentiation (GO:0045628)3.10011108
88low-density lipoprotein particle clearance (GO:0034383)3.09358602
89Arp2/3 complex-mediated actin nucleation (GO:0034314)3.08637302
90positive regulation of T cell mediated cytotoxicity (GO:0001916)3.08343518
91response to protozoan (GO:0001562)3.08198613
92lipopolysaccharide-mediated signaling pathway (GO:0031663)3.07599823
93positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.05009884
94positive thymic T cell selection (GO:0045059)3.03878957
95regulation of natural killer cell mediated immunity (GO:0002715)3.03471949
96regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.03471949
97neutrophil chemotaxis (GO:0030593)3.03310907
98monocyte chemotaxis (GO:0002548)3.02078608
99negative regulation of innate immune response (GO:0045824)3.01762176
100tolerance induction (GO:0002507)3.01236001
101T cell migration (GO:0072678)3.00992747
102positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.00048439
103lipoprotein transport (GO:0042953)2.99350348
104positive regulation of cellular amide metabolic process (GO:0034250)2.98535219
105negative T cell selection (GO:0043383)2.97839261
106myeloid leukocyte activation (GO:0002274)2.97566183
107positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.96875635
108negative regulation of interleukin-6 production (GO:0032715)2.96332477
109neutrophil migration (GO:1990266)2.94378961
110regulation of alpha-beta T cell proliferation (GO:0046640)2.93412272
111lymphocyte mediated immunity (GO:0002449)2.92886338
112cell adhesion mediated by integrin (GO:0033627)2.91786128
113regulation of regulated secretory pathway (GO:1903305)2.91584812
114production of molecular mediator involved in inflammatory response (GO:0002532)2.90888742
115NIK/NF-kappaB signaling (GO:0038061)2.89048905
116* leukocyte migration involved in inflammatory response (GO:0002523)2.88746696
117regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.86986193
118positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.86425057
119leukocyte aggregation (GO:0070486)2.86120953
120germinal center formation (GO:0002467)2.85926000
121positive regulation of leukocyte degranulation (GO:0043302)2.85314376
122myeloid dendritic cell differentiation (GO:0043011)2.85121216
123regulation of myeloid leukocyte mediated immunity (GO:0002886)2.82966742
124positive regulation of mast cell degranulation (GO:0043306)2.82688028
125positive regulation of mast cell activation involved in immune response (GO:0033008)2.82688028
126hydrogen peroxide biosynthetic process (GO:0050665)2.82680292
127interferon-gamma-mediated signaling pathway (GO:0060333)2.82577089
128phagosome maturation (GO:0090382)2.81498211
129positive regulation of chemokine biosynthetic process (GO:0045080)2.81092233
130adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.80318864
131myeloid dendritic cell activation (GO:0001773)2.80213967
132dendritic cell differentiation (GO:0097028)2.79414382
133apoptotic cell clearance (GO:0043277)2.78959655
134positive regulation of macrophage cytokine production (GO:0060907)2.78770218
135defense response to protozoan (GO:0042832)2.78657622
136negative regulation of lipid storage (GO:0010888)2.78421846
137detection of molecule of bacterial origin (GO:0032490)2.77110083
138regulation of interleukin-12 biosynthetic process (GO:0045075)2.75906117
139negative regulation of interleukin-12 production (GO:0032695)2.72587183
140regulation of integrin activation (GO:0033623)2.72528762
141leukocyte mediated immunity (GO:0002443)2.71872161
142leukocyte degranulation (GO:0043299)2.71523390
143positive regulation of interleukin-12 production (GO:0032735)2.71113183

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse6.73506268
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.68766613
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.82243684
4IRF8_27001747_Chip-Seq_BMDM_Mouse4.65065084
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.54607523
6Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse4.31569556
7NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.97222988
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.50020201
9MYB_21317192_ChIP-Seq_ERMYB_Mouse3.31116973
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.10965671
11EGR1_19374776_ChIP-ChIP_THP-1_Human3.05084920
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.95314708
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.89141475
14NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.77405085
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.75152039
16STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.66564903
17BRD4_27068464_Chip-Seq_AML-cells_Mouse2.59692097
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.52067988
19RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.50997954
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.47743219
21SPI1_23127762_ChIP-Seq_K562_Human2.31409349
22SPI1_23547873_ChIP-Seq_NB4_Human2.26877017
23PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.14322879
24STAT4_19710469_ChIP-ChIP_TH1__Mouse2.07695466
25VDR_21846776_ChIP-Seq_THP-1_Human2.00196156
26VDR_24763502_ChIP-Seq_THP-1_Human1.99654043
27PU_27001747_Chip-Seq_BMDM_Mouse1.97204729
28VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.94712981
29VDR_24787735_ChIP-Seq_THP-1_Human1.93176254
30* RUNX1_22412390_ChIP-Seq_EML_Mouse1.85764265
31ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.81072774
32SCL_19346495_ChIP-Seq_HPC-7_Human1.80030704
33TP63_17297297_ChIP-ChIP_HaCaT_Human1.79376038
34RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.73032190
35CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.71973922
36MAF_26560356_Chip-Seq_TH1_Human1.64567139
37CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.64287267
38NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.61382722
39RUNX_20019798_ChIP-Seq_JUKART_Human1.61020500
40* MYB_26560356_Chip-Seq_TH2_Human1.60472588
41PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.60197439
42FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.53271448
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.48439335
44E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.47152780
45GATA2_21666600_ChIP-Seq_HMVEC_Human1.46613847
46MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.45183724
47E2F7_22180533_ChIP-Seq_HELA_Human1.45069456
48STAT6_21828071_ChIP-Seq_BEAS2B_Human1.43455964
49MYB_26560356_Chip-Seq_TH1_Human1.40872555
50CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39478495
51TFEB_21752829_ChIP-Seq_HELA_Human1.37620845
52LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.37329354
53STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.36215002
54CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.34308195
55TCF7_22412390_ChIP-Seq_EML_Mouse1.34224864
56CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.33942776
57TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30973533
58ELK3_25401928_ChIP-Seq_HUVEC_Human1.29238795
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.28735925
60KDM2B_26808549_Chip-Seq_JURKAT_Human1.26906187
61STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.26538942
62SMAD_19615063_ChIP-ChIP_OVARY_Human1.26419421
63BCL6_27268052_Chip-Seq_Bcells_Human1.22748644
64TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21415322
65SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.21232337
66PU.1_20513432_ChIP-Seq_Bcells_Mouse1.20727103
67PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.18935412
68BCOR_27268052_Chip-Seq_Bcells_Human1.17611294
69GATA3_27048872_Chip-Seq_THYMUS_Human1.17557273
70UTX_26944678_Chip-Seq_JUKART_Human1.16918222
71KDM2B_26808549_Chip-Seq_SUP-B15_Human1.15660083
72GATA2_22383799_ChIP-Seq_G1ME_Mouse1.11833410
73SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11346294
74PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10722279
75IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08782615
76LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07050714
77VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.05384547
78ELF1_17652178_ChIP-ChIP_JURKAT_Human1.05381216
79TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.05246520
80* GATA3_26560356_Chip-Seq_TH2_Human1.04169518
81KDM2B_26808549_Chip-Seq_DND41_Human1.03759233
82CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.03744650
83FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03717127
84NCOR1_26117541_ChIP-Seq_K562_Human1.03463181
85GATA1_22025678_ChIP-Seq_K562_Human1.03040085
86SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.02826593
87* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.01824930
88MYC_22102868_ChIP-Seq_BL_Human1.01126613
89FOXO3_23340844_ChIP-Seq_DLD1_Human1.00139145
90KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.98787785
91* RACK7_27058665_Chip-Seq_MCF-7_Human0.97277378
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.95899916
93TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.94640486
94* SA1_27219007_Chip-Seq_ERYTHROID_Human0.93428166
95SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.92583905
96SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.92583905
97GATA1_19941827_ChIP-Seq_MEL_Mouse0.92453781
98* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92031822
99ELF1_20517297_ChIP-Seq_JURKAT_Human0.91334124
100GATA1_22383799_ChIP-Seq_G1ME_Mouse0.91088091
101KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.90412784
102TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.88821350
103GATA1_19941826_ChIP-Seq_K562_Human0.87691386
104ESR1_21235772_ChIP-Seq_MCF-7_Human0.86873379
105GATA2_19941826_ChIP-Seq_K562_Human0.86340540
106GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.85671274
107* MAF_26560356_Chip-Seq_TH2_Human0.85034228
108* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.83206636
109GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82988232
110GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82115676
111LXR_22292898_ChIP-Seq_THP-1_Human0.82054548
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.81464211
113CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.81067720
114FOXM1_23109430_ChIP-Seq_U2OS_Human0.79996050
115JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.79315302
116CDX2_19796622_ChIP-Seq_MESCs_Mouse0.79155566
117RARG_19884340_ChIP-ChIP_MEFs_Mouse0.78825323
118SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.78746578
119JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78540402
120SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.78484463

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.44997837
2MP0001835_abnormal_antigen_presentation4.01520596
3MP0003303_peritoneal_inflammation3.95232957
4MP0000569_abnormal_digit_pigmentation3.94199602
5MP0003172_abnormal_lysosome_physiology3.57934845
6* MP0003436_decreased_susceptibility_to3.25611409
7MP0006082_CNS_inflammation3.25183638
8MP0002419_abnormal_innate_immunity3.08337303
9MP0004510_myositis2.70090624
10MP0009785_altered_susceptibility_to2.68170865
11* MP0005000_abnormal_immune_tolerance2.66472037
12MP0001790_abnormal_immune_system2.54842435
13MP0005387_immune_system_phenotype2.54842435
14MP0000685_abnormal_immune_system2.50056529
15MP0002148_abnormal_hypersensitivity_rea2.49078316
16MP0005025_abnormal_response_to2.46220749
17MP0002452_abnormal_antigen_presenting2.43150086
18MP0001800_abnormal_humoral_immune2.26196533
19MP0002723_abnormal_immune_serum2.17302590
20MP0003300_gastrointestinal_ulcer2.16329603
21MP0009278_abnormal_bone_marrow2.06386091
22MP0005464_abnormal_platelet_physiology2.06051745
23MP0001819_abnormal_immune_cell2.02213179
24MP0002420_abnormal_adaptive_immunity1.99961475
25MP0009840_abnormal_foam_cell1.97288889
26MP0003183_abnormal_peptide_metabolism1.97157140
27MP0000604_amyloidosis1.96181161
28MP0005671_abnormal_response_to1.93857856
29MP0003448_altered_tumor_morphology1.88782341
30MP0005310_abnormal_salivary_gland1.86254062
31MP0002405_respiratory_system_inflammati1.84875841
32MP0002254_reproductive_system_inflammat1.81315480
33MP0010307_abnormal_tumor_latency1.78628092
34MP0004947_skin_inflammation1.77602430
35* MP0001533_abnormal_skeleton_physiology1.75425860
36MP0005257_abnormal_intraocular_pressure1.67640386
37MP0002132_abnormal_respiratory_system1.67268997
38MP0005174_abnormal_tail_pigmentation1.66779836
39MP0003191_abnormal_cellular_cholesterol1.64748156
40MP0001845_abnormal_inflammatory_respons1.62644685
41MP0005451_abnormal_body_composition1.62032761
42MP0002166_altered_tumor_susceptibility1.59265950
43MP0000343_altered_response_to1.56930498
44MP0003566_abnormal_cell_adhesion1.56674157
45MP0003724_increased_susceptibility_to1.54873769
46MP0003690_abnormal_glial_cell1.54851941
47MP0001853_heart_inflammation1.46654576
48MP0000716_abnormal_immune_system1.44777686
49MP0001545_abnormal_hematopoietic_system1.44755828
50MP0005397_hematopoietic_system_phenotyp1.44755828
51MP0003866_abnormal_defecation1.43721645
52MP0008469_abnormal_protein_level1.41633836
53MP0003075_altered_response_to1.37001354
54MP0002398_abnormal_bone_marrow1.33794962
55MP0000689_abnormal_spleen_morphology1.33224704
56MP0002006_tumorigenesis1.31980465
57MP0000858_altered_metastatic_potential1.31967192
58MP0002998_abnormal_bone_remodeling1.27709596
59MP0005076_abnormal_cell_differentiation1.26861949
60MP0001851_eye_inflammation1.26243695
61MP0009764_decreased_sensitivity_to1.21653819
62MP0010155_abnormal_intestine_physiology1.21389528
63MP0004381_abnormal_hair_follicle1.20305465
64MP0000015_abnormal_ear_pigmentation1.20014852
65MP0004883_abnormal_blood_vessel1.18943810
66MP0002429_abnormal_blood_cell1.16742802
67MP0009333_abnormal_splenocyte_physiolog1.15106779
68MP0005166_decreased_susceptibility_to1.14881827
69MP0000465_gastrointestinal_hemorrhage1.14812131
70MP0002722_abnormal_immune_system1.14162421
71MP0001958_emphysema1.14045348
72MP0001873_stomach_inflammation1.11474092
73MP0005167_abnormal_blood-brain_barrier1.09170553
74MP0002277_abnormal_respiratory_mucosa1.08431597
75MP0002933_joint_inflammation1.06321416
76MP0003091_abnormal_cell_migration1.03007668
77MP0003828_pulmonary_edema1.02341818
78MP0003806_abnormal_nucleotide_metabolis1.01132899
79MP0003656_abnormal_erythrocyte_physiolo0.97936120
80MP0008004_abnormal_stomach_pH0.95777806
81MP0000371_diluted_coat_color0.92897719
82MP0009763_increased_sensitivity_to0.86762697
83MP0002138_abnormal_hepatobiliary_system0.86162326
84MP0005083_abnormal_biliary_tract0.85665388
85MP0003705_abnormal_hypodermis_morpholog0.82455328
86MP0004808_abnormal_hematopoietic_stem0.80455787
87MP0008260_abnormal_autophagy0.80255533
88MP0003045_fibrosis0.77973497
89* MP0005390_skeleton_phenotype0.77504803
90MP0003453_abnormal_keratinocyte_physiol0.75496782
91MP0005023_abnormal_wound_healing0.73215400
92MP0005164_abnormal_response_to0.72285860
93MP0009765_abnormal_xenobiotic_induced0.71259237
94MP0008874_decreased_physiological_sensi0.70757494
95MP0000490_abnormal_crypts_of0.70142498
96MP0002396_abnormal_hematopoietic_system0.69480856
97MP0002332_abnormal_exercise_endurance0.69204175
98MP0003795_abnormal_bone_structure0.68856091
99MP0005197_abnormal_uvea_morphology0.68617242
100MP0000249_abnormal_blood_vessel0.68146915
101MP0008438_abnormal_cutaneous_collagen0.67405650
102MP0002090_abnormal_vision0.64370840
103MP0000703_abnormal_thymus_morphology0.63611534
104MP0001663_abnormal_digestive_system0.61207639
105MP0003221_abnormal_cardiomyocyte_apopto0.60508319
106MP0000767_abnormal_smooth_muscle0.59745696
107MP0010352_gastrointestinal_tract_polyps0.58405795
108MP0005075_abnormal_melanosome_morpholog0.57935690
109MP0001915_intracranial_hemorrhage0.55429023
110MP0003634_abnormal_glial_cell0.55399157
111MP0000920_abnormal_myelination0.55127626
112MP0002136_abnormal_kidney_physiology0.54759659
113MP0005319_abnormal_enzyme/_coenzyme0.53962184
114MP0003763_abnormal_thymus_physiology0.52462087
115MP0002019_abnormal_tumor_incidence0.49552228
116MP0001986_abnormal_taste_sensitivity0.48093807
117MP0002693_abnormal_pancreas_physiology0.47120523
118MP0000609_abnormal_liver_physiology0.46277868
119MP0005381_digestive/alimentary_phenotyp0.46068677

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.91773419
2Increased cerebral lipofuscin (HP:0011813)6.38591326
3Recurrent bacterial skin infections (HP:0005406)5.97436146
4Vacuolated lymphocytes (HP:0001922)5.82524767
5Eczematoid dermatitis (HP:0000976)5.68713130
6Increased neuronal autofluorescent lipopigment (HP:0002074)5.37075914
7Recurrent gram-negative bacterial infections (HP:0005420)5.16075793
8Abnormality of macrophages (HP:0004311)5.09430244
9Dysostosis multiplex (HP:0000943)4.51078361
10Disinhibition (HP:0000734)4.30224165
11Abnormality of glycolipid metabolism (HP:0010969)4.29487703
12Abnormality of liposaccharide metabolism (HP:0010968)4.29487703
13Abnormality of glycosphingolipid metabolism (HP:0004343)4.29487703
14Gastrointestinal infarctions (HP:0005244)4.11981401
15Axonal loss (HP:0003447)4.08008656
16Systemic lupus erythematosus (HP:0002725)3.90448852
17Gingivitis (HP:0000230)3.86732942
18Abnormal delayed hypersensitivity skin test (HP:0002963)3.83991995
19Urinary glycosaminoglycan excretion (HP:0003541)3.80387764
20Mucopolysacchariduria (HP:0008155)3.80387764
21Increased IgE level (HP:0003212)3.79522865
22Mediastinal lymphadenopathy (HP:0100721)3.75729021
23Myositis (HP:0100614)3.74113486
24Abnormality of polysaccharide metabolism (HP:0011012)3.71033298
25Abnormality of glycosaminoglycan metabolism (HP:0004371)3.71033298
26Abnormality of mucopolysaccharide metabolism (HP:0011020)3.71033298
27Prostate neoplasm (HP:0100787)3.68764084
28Recurrent skin infections (HP:0001581)3.68479600
29Keratoconjunctivitis sicca (HP:0001097)3.62571014
30Encephalitis (HP:0002383)3.61150405
31Chronic obstructive pulmonary disease (HP:0006510)3.52542730
32Obstructive lung disease (HP:0006536)3.52542730
33Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.52416441
34Loss of speech (HP:0002371)3.52216513
35Autoimmune thrombocytopenia (HP:0001973)3.46215886
36Orchitis (HP:0100796)3.42802096
37Recurrent fungal infections (HP:0002841)3.34481583
38Agnosia (HP:0010524)3.18042023
39Chest pain (HP:0100749)3.16352511
40Prolonged bleeding time (HP:0003010)3.15528482
41Retrobulbar optic neuritis (HP:0100654)3.14512956
42Optic neuritis (HP:0100653)3.14512956
43Myocardial infarction (HP:0001658)3.08535028
44Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.06817932
45Stomatitis (HP:0010280)3.06191098
46Episodic fever (HP:0001954)3.02864727
47Elevated erythrocyte sedimentation rate (HP:0003565)2.98203951
48Periodontitis (HP:0000704)2.97110804
49Hypochromic microcytic anemia (HP:0004840)2.86467639
50T lymphocytopenia (HP:0005403)2.85359897
51Hypochromic anemia (HP:0001931)2.81095207
52Upper motor neuron abnormality (HP:0002127)2.79910407
53Amyloidosis (HP:0011034)2.78464677
54Basal ganglia calcification (HP:0002135)2.75987556
55Thick nail (HP:0001805)2.75205908
56Abnormality of T cell number (HP:0011839)2.74485855
57Increased IgM level (HP:0003496)2.71921429
58J-shaped sella turcica (HP:0002680)2.67989602
59Epistaxis (HP:0000421)2.65008045
60Anorexia (HP:0002039)2.64796097
61Pustule (HP:0200039)2.64563841
62Petechiae (HP:0000967)2.64538455
63Urticaria (HP:0001025)2.62300307
64Panhypogammaglobulinemia (HP:0003139)2.62243597
65Vasculitis (HP:0002633)2.59112654
66Pathologic fracture (HP:0002756)2.55914400
67Hepatosplenomegaly (HP:0001433)2.55138085
68Recurrent viral infections (HP:0004429)2.53954146
69Abnormality of T cells (HP:0002843)2.51409654
70Pulmonary embolism (HP:0002204)2.50087865
71Recurrent cutaneous fungal infections (HP:0011370)2.48468133
72Chronic mucocutaneous candidiasis (HP:0002728)2.48468133
73Glomerulonephritis (HP:0000099)2.48353876
74Cellulitis (HP:0100658)2.46758777
75Granulocytopenia (HP:0001913)2.45675685
76Apathy (HP:0000741)2.43889055
77Abnormality of the vasculature of the conjunctiva (HP:0008054)2.43585295
78Diminished motivation (HP:0000745)2.41701335
79Thoracic kyphosis (HP:0002942)2.41500015
80Lymphopenia (HP:0001888)2.40974270
81Peritonitis (HP:0002586)2.40438033
82Sepsis (HP:0100806)2.37844760
83Abnormality of the lumbar spine (HP:0100712)2.36535553
84Hematochezia (HP:0002573)2.35393038
85Increased serum ferritin (HP:0003281)2.34771421
86Osteomyelitis (HP:0002754)2.34711269
87Hypergammaglobulinemia (HP:0010702)2.34033181
88Gangrene (HP:0100758)2.32542199
89Inappropriate behavior (HP:0000719)2.30337593
90Abnormality of the pleura (HP:0002103)2.27932110
91Global brain atrophy (HP:0002283)2.27803390
92Abnormality of cells of the lymphoid lineage (HP:0012140)2.26959008
93Leukocytosis (HP:0001974)2.26659558
94Interstitial pulmonary disease (HP:0006530)2.23630309
95Peripheral demyelination (HP:0011096)2.22810784
96Pulmonary infiltrates (HP:0002113)2.20760244
97Purpura (HP:0000979)2.20131128
98Abnormality of T cell physiology (HP:0011840)2.19870259
99Arterial thrombosis (HP:0004420)2.19724713
100Neuronal loss in central nervous system (HP:0002529)2.19665044
101Skin ulcer (HP:0200042)2.15106583
102Bone pain (HP:0002653)2.14158528
103Glomerulopathy (HP:0100820)2.13609787
104Agammaglobulinemia (HP:0004432)2.12908147
105Gastrointestinal stroma tumor (HP:0100723)2.11242999
106Tetraparesis (HP:0002273)2.11154195
107Personality changes (HP:0000751)2.10446490
108Microcytic anemia (HP:0001935)2.10242590
109Osteolytic defects of the phalanges of the hand (HP:0009771)2.09447903
110Osteolytic defects of the hand bones (HP:0009699)2.09447903
111Chronic otitis media (HP:0000389)2.09090608
112Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.08366800
113Conjunctival telangiectasia (HP:0000524)2.08041648
114Abnormality of the peritoneum (HP:0002585)2.07826289
115Abnormality of iron homeostasis (HP:0011031)2.07476327
116Premature loss of primary teeth (HP:0006323)2.07302357
117IgM deficiency (HP:0002850)2.05762315
118Meningitis (HP:0001287)2.05530008
119Recurrent pneumonia (HP:0006532)2.03227901
120Abnormality of the endocardium (HP:0004306)2.02913866
121Gingival bleeding (HP:0000225)2.01726844
122Colitis (HP:0002583)2.00775041
123Slow saccadic eye movements (HP:0000514)1.99887257
124Spontaneous hematomas (HP:0007420)1.99782885
125Abnormality of the prostate (HP:0008775)1.99716726
126Abnormality of the thoracic spine (HP:0100711)1.97875211
127Acne (HP:0001061)1.97200903
128Inflammation of the large intestine (HP:0002037)1.96650756
129Keratitis (HP:0000491)1.92807107
130Abnormality of the pericardium (HP:0001697)1.92568849
131Restrictive lung disease (HP:0002091)1.92232943
132Recurrent bronchitis (HP:0002837)1.91132952
133Progressive visual loss (HP:0000529)1.90500170
134Vertigo (HP:0002321)1.89251662
135Autoimmune hemolytic anemia (HP:0001890)1.89143037
136Asymmetric septal hypertrophy (HP:0001670)1.87698610
137Viral hepatitis (HP:0006562)1.87628382
138Frequent falls (HP:0002359)1.87248797
139Supranuclear gaze palsy (HP:0000605)1.85553988
140Increased CSF protein (HP:0002922)1.84180969
141Vertebral compression fractures (HP:0002953)1.83906556
142Keratoconjunctivitis (HP:0001096)1.83704532
143Nephritis (HP:0000123)1.82583281
144Gastrointestinal inflammation (HP:0004386)1.81901393
145Esophageal varix (HP:0002040)1.81312323
146Mutism (HP:0002300)1.80337641
147Hemoptysis (HP:0002105)1.80042835
148Deformed sella turcica (HP:0002681)1.79623847
149Neurodegeneration (HP:0002180)1.78907662
150Eosinophilia (HP:0001880)1.78439815

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K143.61439610
2KIT3.57705752
3RIPK43.51871339
4TBK13.45284066
5TYK23.06936230
6IRAK43.00311922
7PRPF4B2.71957333
8BLK2.34413496
9TNK22.30953155
10NME22.21217118
11ERN12.17312713
12MAP3K132.16030885
13IRAK32.11702983
14IKBKB2.09864803
15MAP4K12.09556303
16FES2.08056313
17TTN2.06604364
18IKBKE2.04756057
19TAOK32.03982710
20TAOK11.94693414
21JAK31.93487809
22CSF1R1.82472279
23JAK11.77321270
24HCK1.73246884
25EPHB11.72885208
26SIK31.62124476
27TGFBR21.60080127
28FGR1.57011180
29CSK1.54564066
30SYK1.52407360
31CAMK1D1.52004140
32MAP2K31.47861854
33TRIB31.42963455
34SIK21.40559249
35NEK91.39431318
36ZAP701.35745104
37CHUK1.28649375
38PIM21.25986109
39PTK61.24447201
40SCYL21.23286241
41STK101.22183502
42BTK1.20263292
43LCK1.20121576
44MAP3K31.19849589
45PKN21.16933842
46JAK21.12493381
47LYN1.09923454
48PBK1.09381992
49RPS6KA41.08982512
50RIPK11.07340299
51CAMK1G1.06601607
52PRKD21.04274549
53SMG11.03065108
54MARK21.02866205
55TXK1.02643492
56TRPM70.99273096
57ITK0.95176716
58YES10.93796519
59MATK0.92091769
60SIK10.90052458
61TEC0.89284275
62IRAK20.89217621
63EGFR0.88760464
64IRAK10.87960971
65CDC42BPA0.83488252
66LRRK20.83251974
67PIM10.82701747
68MOS0.81645383
69CAMKK20.79972711
70MAP3K110.78111368
71BMPR20.76120140
72CDK60.74873493
73ABL10.74543990
74BMX0.72823478
75PRKCD0.72318510
76PAK40.71741971
77MAP3K70.68408864
78GRK60.68105041
79HIPK20.65408948
80MARK30.64581057
81MAP3K60.63815792
82CDK190.63092718
83FGFR30.62677260
84MAPK120.62521102
85CDK120.60747562
86ABL20.58822576
87STK40.58218799
88MAP3K50.57701403
89MAPK70.57319980
90TESK20.55658149
91TAOK20.54728246
92FYN0.53470082
93CAMKK10.53238267
94KSR20.53000338
95TESK10.52187147
96DYRK1B0.52088259
97MAP3K90.52023338
98MAP3K10.50485267
99DAPK20.49728760
100RPS6KL10.49003450
101RPS6KC10.49003450
102PTK2B0.48855371
103FGFR40.48656748
104ERBB30.47492274
105MAP2K60.47460491
106MAPKAPK20.43071353
107EPHA30.42483639
108STK380.41970373
109STK110.40856613
110MAP3K80.40054808
111MAP2K40.40040734
112MAP3K20.38996099
113SRC0.38434892
114STK30.38102510
115CLK10.38016126
116SGK30.37639711
117PDPK10.37532748
118PRKG20.37420708
119GRK70.35821996
120PDGFRB0.34780501
121PRKCH0.34572589
122RET0.34306839
123PDK10.33817965
124RPS6KA60.33554014
125RAF10.32891001
126DAPK30.32811929
127PTK20.32224457
128NEK20.31327197
129PRKCQ0.30491492
130IGF1R0.29532880
131CDK40.28872204
132RPS6KA20.27505718

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.16415055
2Lysosome_Homo sapiens_hsa041423.12809180
3Glycosaminoglycan degradation_Homo sapiens_hsa005313.10253692
4Staphylococcus aureus infection_Homo sapiens_hsa051503.05117104
5Osteoclast differentiation_Homo sapiens_hsa043802.61696624
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.55132240
7Other glycan degradation_Homo sapiens_hsa005112.36763082
8Tuberculosis_Homo sapiens_hsa051522.27009455
9Phagosome_Homo sapiens_hsa041452.20752702
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.20228470
11Pertussis_Homo sapiens_hsa051332.07003786
12Malaria_Homo sapiens_hsa051442.02709531
13B cell receptor signaling pathway_Homo sapiens_hsa046621.99900431
14Legionellosis_Homo sapiens_hsa051341.94648656
15Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.87995339
16Rheumatoid arthritis_Homo sapiens_hsa053231.81621637
17Measles_Homo sapiens_hsa051621.72996888
18NOD-like receptor signaling pathway_Homo sapiens_hsa046211.66730676
19Allograft rejection_Homo sapiens_hsa053301.61969473
20Toxoplasmosis_Homo sapiens_hsa051451.60750409
21Antigen processing and presentation_Homo sapiens_hsa046121.59479044
22Apoptosis_Homo sapiens_hsa042101.58212213
23Shigellosis_Homo sapiens_hsa051311.57228111
24Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.55816689
25Salmonella infection_Homo sapiens_hsa051321.51833110
26TNF signaling pathway_Homo sapiens_hsa046681.50860354
27Influenza A_Homo sapiens_hsa051641.47571150
28Graft-versus-host disease_Homo sapiens_hsa053321.47256940
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.45636734
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.45321667
31Asthma_Homo sapiens_hsa053101.42328446
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.41296292
33Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.40519333
34Intestinal immune network for IgA production_Homo sapiens_hsa046721.38020993
35Chemokine signaling pathway_Homo sapiens_hsa040621.30984635
36Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.30908683
37Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.27392548
38Hematopoietic cell lineage_Homo sapiens_hsa046401.18155257
39Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.14466953
40Hepatitis B_Homo sapiens_hsa051611.13757405
41Jak-STAT signaling pathway_Homo sapiens_hsa046301.12482969
42Leukocyte transendothelial migration_Homo sapiens_hsa046701.12388694
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.12045563
44Caffeine metabolism_Homo sapiens_hsa002321.10507656
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.10480288
46Viral myocarditis_Homo sapiens_hsa054161.09485997
47Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.07347268
48Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.05403530
49Collecting duct acid secretion_Homo sapiens_hsa049661.04981070
50Chronic myeloid leukemia_Homo sapiens_hsa052201.03065971
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99606870
52Herpes simplex infection_Homo sapiens_hsa051680.98917577
53Pancreatic cancer_Homo sapiens_hsa052120.96875654
54Amoebiasis_Homo sapiens_hsa051460.96700472
55Hepatitis C_Homo sapiens_hsa051600.95848868
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.86913352
57T cell receptor signaling pathway_Homo sapiens_hsa046600.86552116
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.83348778
59Acute myeloid leukemia_Homo sapiens_hsa052210.82362425
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77190928
61African trypanosomiasis_Homo sapiens_hsa051430.76812913
62Regulation of actin cytoskeleton_Homo sapiens_hsa048100.76368907
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.75562986
64Complement and coagulation cascades_Homo sapiens_hsa046100.75523540
65Endocytosis_Homo sapiens_hsa041440.73608293
66Autoimmune thyroid disease_Homo sapiens_hsa053200.70848118
67Sphingolipid signaling pathway_Homo sapiens_hsa040710.70759606
68Platelet activation_Homo sapiens_hsa046110.70291886
69Sphingolipid metabolism_Homo sapiens_hsa006000.65658740
70Proteoglycans in cancer_Homo sapiens_hsa052050.64710442
71Type II diabetes mellitus_Homo sapiens_hsa049300.64251477
72Small cell lung cancer_Homo sapiens_hsa052220.63314227
73Primary immunodeficiency_Homo sapiens_hsa053400.61593894
74VEGF signaling pathway_Homo sapiens_hsa043700.61475361
75Prolactin signaling pathway_Homo sapiens_hsa049170.61408974
76HIF-1 signaling pathway_Homo sapiens_hsa040660.60064310
77Type I diabetes mellitus_Homo sapiens_hsa049400.58083619
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56984591
79FoxO signaling pathway_Homo sapiens_hsa040680.55447986
80Endometrial cancer_Homo sapiens_hsa052130.54457887
81Epstein-Barr virus infection_Homo sapiens_hsa051690.53500078
82GnRH signaling pathway_Homo sapiens_hsa049120.52617364
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51346874
84Viral carcinogenesis_Homo sapiens_hsa052030.50906727
85Choline metabolism in cancer_Homo sapiens_hsa052310.50750314
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.49750190
87MicroRNAs in cancer_Homo sapiens_hsa052060.49055527
88Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48893107
89Colorectal cancer_Homo sapiens_hsa052100.48014401
90Renal cell carcinoma_Homo sapiens_hsa052110.45860297
91MAPK signaling pathway_Homo sapiens_hsa040100.45041072
92Bladder cancer_Homo sapiens_hsa052190.42298521
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.41634020
94Mineral absorption_Homo sapiens_hsa049780.41120628
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40922723
96Glioma_Homo sapiens_hsa052140.40518649
97Rap1 signaling pathway_Homo sapiens_hsa040150.39445037
98Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39134454
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38959050
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.38733029
101Vibrio cholerae infection_Homo sapiens_hsa051100.38645715
102Phospholipase D signaling pathway_Homo sapiens_hsa040720.38547333
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.38256630
104Non-small cell lung cancer_Homo sapiens_hsa052230.37473167
105Renin-angiotensin system_Homo sapiens_hsa046140.37348916
106ErbB signaling pathway_Homo sapiens_hsa040120.36817131
107HTLV-I infection_Homo sapiens_hsa051660.36267456
108Regulation of autophagy_Homo sapiens_hsa041400.36137701
109Focal adhesion_Homo sapiens_hsa045100.34769674
110Insulin resistance_Homo sapiens_hsa049310.32639995
111Dorso-ventral axis formation_Homo sapiens_hsa043200.32144903
112Notch signaling pathway_Homo sapiens_hsa043300.31739452
113mTOR signaling pathway_Homo sapiens_hsa041500.31497871
114Prion diseases_Homo sapiens_hsa050200.30181267
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29644872
116Inositol phosphate metabolism_Homo sapiens_hsa005620.28832024
117Prostate cancer_Homo sapiens_hsa052150.28472008

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