Rank | Gene Set | Z-score |
---|---|---|
1 | protein heterotrimerization (GO:0070208) | 7.26158236 |
2 | collagen fibril organization (GO:0030199) | 6.53455409 |
3 | glomerular basement membrane development (GO:0032836) | 5.70642848 |
4 | chondrocyte proliferation (GO:0035988) | 5.54265050 |
5 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 5.11404305 |
6 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 5.03750376 |
7 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 4.96948249 |
8 | axon extension involved in axon guidance (GO:0048846) | 4.96948249 |
9 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 4.71823407 |
10 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.70953285 |
11 | bone trabecula formation (GO:0060346) | 4.64514412 |
12 | negative regulation of muscle hypertrophy (GO:0014741) | 4.58487002 |
13 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 4.36535025 |
14 | lung lobe morphogenesis (GO:0060463) | 4.31952969 |
15 | regulation of muscle hypertrophy (GO:0014743) | 4.21017116 |
16 | collagen metabolic process (GO:0032963) | 4.20430194 |
17 | glomerular visceral epithelial cell development (GO:0072015) | 4.14640066 |
18 | vascular endothelial growth factor signaling pathway (GO:0038084) | 4.12766792 |
19 | collagen catabolic process (GO:0030574) | 4.10805571 |
20 | metanephric mesenchyme development (GO:0072075) | 4.09405723 |
21 | multicellular organismal macromolecule metabolic process (GO:0044259) | 4.07665540 |
22 | low-density lipoprotein particle clearance (GO:0034383) | 4.05718585 |
23 | mesenchymal-epithelial cell signaling (GO:0060638) | 4.05621717 |
24 | endodermal cell differentiation (GO:0035987) | 4.05273560 |
25 | lung vasculature development (GO:0060426) | 4.02981754 |
26 | basement membrane organization (GO:0071711) | 3.99751743 |
27 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 3.98820690 |
28 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 3.92984248 |
29 | negative regulation of heart growth (GO:0061117) | 3.92984248 |
30 | multicellular organismal metabolic process (GO:0044236) | 3.91869675 |
31 | organ induction (GO:0001759) | 3.87472030 |
32 | kidney mesenchyme development (GO:0072074) | 3.86824721 |
33 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.86624897 |
34 | skin morphogenesis (GO:0043589) | 3.86091230 |
35 | response to gravity (GO:0009629) | 3.84908579 |
36 | dermatan sulfate biosynthetic process (GO:0030208) | 3.84873258 |
37 | regulation of cardiac muscle hypertrophy (GO:0010611) | 3.82324923 |
38 | multicellular organismal catabolic process (GO:0044243) | 3.81776592 |
39 | cellular response to vitamin (GO:0071295) | 3.80548198 |
40 | glomerular filtration (GO:0003094) | 3.78275119 |
41 | extracellular fibril organization (GO:0043206) | 3.75247498 |
42 | glomerular epithelial cell development (GO:0072310) | 3.69598430 |
43 | regulation of cardiac muscle cell differentiation (GO:2000725) | 3.68208023 |
44 | renal filtration (GO:0097205) | 3.65947366 |
45 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.64491438 |
46 | apoptotic cell clearance (GO:0043277) | 3.63622646 |
47 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 3.50872877 |
48 | dermatan sulfate metabolic process (GO:0030205) | 3.50725475 |
49 | negative regulation of gluconeogenesis (GO:0045721) | 3.50179740 |
50 | negative regulation of fatty acid transport (GO:2000192) | 3.48264849 |
51 | barbed-end actin filament capping (GO:0051016) | 3.46760909 |
52 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.46531886 |
53 | ovulation from ovarian follicle (GO:0001542) | 3.45265663 |
54 | negative regulation of cartilage development (GO:0061037) | 3.43796048 |
55 | fibril organization (GO:0097435) | 3.39933932 |
56 | lymphangiogenesis (GO:0001946) | 3.39132487 |
57 | cell adhesion mediated by integrin (GO:0033627) | 3.37990938 |
58 | positive regulation of fatty acid oxidation (GO:0046321) | 3.37725674 |
59 | extracellular matrix assembly (GO:0085029) | 3.36698688 |
60 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.36237956 |
61 | lymph vessel development (GO:0001945) | 3.35716757 |
62 | * extracellular matrix disassembly (GO:0022617) | 3.34827661 |
63 | negative regulation of protein localization to cell surface (GO:2000009) | 3.34786697 |
64 | negative regulation of cardiac muscle tissue development (GO:0055026) | 3.33060842 |
65 | epoxygenase P450 pathway (GO:0019373) | 3.31452939 |
66 | smooth muscle tissue development (GO:0048745) | 3.29643492 |
67 | regulation of integrin-mediated signaling pathway (GO:2001044) | 3.29429682 |
68 | chondroitin sulfate catabolic process (GO:0030207) | 3.26302485 |
69 | keratan sulfate catabolic process (GO:0042340) | 3.26076051 |
70 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.26042966 |
71 | white fat cell differentiation (GO:0050872) | 3.24347249 |
72 | exocrine pancreas development (GO:0031017) | 3.23872932 |
73 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 3.23067859 |
74 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.17948694 |
75 | embryonic cranial skeleton morphogenesis (GO:0048701) | 3.17405998 |
76 | branching involved in prostate gland morphogenesis (GO:0060442) | 3.17017472 |
77 | protein localization to cell surface (GO:0034394) | 3.15269035 |
78 | regulation of chondrocyte differentiation (GO:0032330) | 3.14720171 |
79 | negative regulation of androgen receptor signaling pathway (GO:0060766) | 3.13157819 |
80 | type B pancreatic cell proliferation (GO:0044342) | 3.12284505 |
81 | negative regulation of BMP signaling pathway (GO:0030514) | 3.12280185 |
82 | blood vessel maturation (GO:0001955) | 3.11562684 |
83 | endothelial cell morphogenesis (GO:0001886) | 3.10425857 |
84 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.10357211 |
85 | wound healing, spreading of epidermal cells (GO:0035313) | 3.10166854 |
86 | cardiac epithelial to mesenchymal transition (GO:0060317) | 3.09033449 |
87 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.06221127 |
88 | positive regulation of extracellular matrix organization (GO:1903055) | 3.06208928 |
89 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 3.06127289 |
90 | positive regulation of muscle hypertrophy (GO:0014742) | 3.06127289 |
91 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 3.05585827 |
92 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 3.05366091 |
93 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.05110173 |
94 | chondrocyte development (GO:0002063) | 3.04058019 |
95 | extracellular negative regulation of signal transduction (GO:1900116) | 3.02457118 |
96 | extracellular regulation of signal transduction (GO:1900115) | 3.02457118 |
97 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 3.02225311 |
98 | craniofacial suture morphogenesis (GO:0097094) | 3.00756240 |
99 | regulation of organ formation (GO:0003156) | 2.98838401 |
100 | regulation of cartilage development (GO:0061035) | 2.98360201 |
101 | epithelial cell-cell adhesion (GO:0090136) | 2.96079655 |
102 | regulation of muscle adaptation (GO:0043502) | 2.94439874 |
103 | * extracellular matrix organization (GO:0030198) | 2.94404278 |
104 | * extracellular structure organization (GO:0043062) | 2.93218960 |
105 | positive regulation of glycolytic process (GO:0045821) | 2.90876346 |
106 | hippo signaling (GO:0035329) | 2.90195857 |
107 | membrane raft organization (GO:0031579) | 2.88970381 |
108 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.88885763 |
109 | cell proliferation involved in metanephros development (GO:0072203) | 2.86473770 |
110 | cell migration involved in heart development (GO:0060973) | 2.85173681 |
111 | plasma membrane repair (GO:0001778) | 2.83495367 |
112 | lung secretory cell differentiation (GO:0061140) | 2.83159685 |
113 | blood vessel remodeling (GO:0001974) | 2.82395429 |
114 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.81772697 |
115 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.81230101 |
116 | regulation of tight junction assembly (GO:2000810) | 2.81219348 |
117 | negative regulation of catenin import into nucleus (GO:0035414) | 2.80349023 |
118 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.78595805 |
119 | protein retention in ER lumen (GO:0006621) | 2.77853005 |
120 | omega-hydroxylase P450 pathway (GO:0097267) | 2.77552900 |
121 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.76610398 |
122 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 2.75664397 |
123 | positive regulation of smooth muscle cell migration (GO:0014911) | 2.74856751 |
124 | mammary gland development (GO:0030879) | 2.74520934 |
125 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.73555923 |
126 | stress fiber assembly (GO:0043149) | 2.73353311 |
127 | peptide cross-linking (GO:0018149) | 2.72738012 |
128 | fibroblast migration (GO:0010761) | 2.71622124 |
129 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.67545948 |
130 | regulation of sequestering of triglyceride (GO:0010889) | 2.67384345 |
131 | negative regulation of leukocyte chemotaxis (GO:0002689) | 2.65346742 |
132 | pattern specification involved in kidney development (GO:0061004) | 2.65213688 |
133 | substrate-dependent cell migration (GO:0006929) | 2.65097540 |
134 | regulation of smooth muscle cell migration (GO:0014910) | 2.64951731 |
135 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.64272447 |
136 | iron ion import (GO:0097286) | 2.64064389 |
137 | regulation of epithelial cell differentiation involved in kidney development (GO:2000696) | 2.63976832 |
138 | growth hormone receptor signaling pathway (GO:0060396) | 2.63966605 |
139 | middle ear morphogenesis (GO:0042474) | 2.63096430 |
140 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.62797793 |
141 | glomerulus development (GO:0032835) | 2.62764633 |
142 | virion attachment to host cell (GO:0019062) | 2.62563100 |
143 | adhesion of symbiont to host cell (GO:0044650) | 2.62563100 |
144 | regulation of cardiac muscle tissue growth (GO:0055021) | 2.62207216 |
145 | muscle cell cellular homeostasis (GO:0046716) | 2.61982533 |
146 | positive regulation of mesenchymal cell proliferation (GO:0002053) | 2.61549058 |
147 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.61409967 |
148 | regulation of gastrulation (GO:0010470) | 2.60532556 |
149 | gonadal mesoderm development (GO:0007506) | 2.60253160 |
150 | cell proliferation involved in kidney development (GO:0072111) | 2.59876576 |
151 | brown fat cell differentiation (GO:0050873) | 2.57612481 |
152 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.57197478 |
153 | outer ear morphogenesis (GO:0042473) | 2.57043236 |
154 | cellular response to interferon-alpha (GO:0035457) | 2.56715683 |
155 | trabecula formation (GO:0060343) | 2.55748532 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 6.58246084 |
2 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.94690075 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 4.28750083 |
4 | CLOCK_20551151_ChIP-Seq_293T_Human | 3.66616971 |
5 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.59405898 |
6 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.54450871 |
7 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.83455967 |
8 | * CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.75220786 |
9 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.70820039 |
10 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.65961684 |
11 | CJUN_26792858_Chip-Seq_BT549_Human | 2.63501473 |
12 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 2.56612242 |
13 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.56070059 |
14 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.43976782 |
15 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.42119379 |
16 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 2.14550346 |
17 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 2.14550346 |
18 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.06623405 |
19 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.00531214 |
20 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.99424257 |
21 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.92878305 |
22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.85314947 |
23 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.83183419 |
24 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.82703453 |
25 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.81641691 |
26 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.81138327 |
27 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.77222771 |
28 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.73934819 |
29 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.73425245 |
30 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.73425245 |
31 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.69868722 |
32 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.60801152 |
33 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.58478371 |
34 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.57216497 |
35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.55290951 |
36 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.55270677 |
37 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.55046787 |
38 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.49388752 |
39 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.48330741 |
40 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.46798918 |
41 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.46403118 |
42 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.46361835 |
43 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.44423075 |
44 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.44341009 |
45 | TP53_16413492_ChIP-PET_HCT116_Human | 1.43632111 |
46 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.43458370 |
47 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.41589651 |
48 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 1.39251205 |
49 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.38702540 |
50 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.37427597 |
51 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.37427597 |
52 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.36100933 |
53 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.34529447 |
54 | * RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.34388666 |
55 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.33256884 |
56 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.31734791 |
57 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.29872965 |
58 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.29611191 |
59 | * TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.29507395 |
60 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.29288817 |
61 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.29288817 |
62 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.29242748 |
63 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.25977832 |
64 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.22925020 |
65 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21822727 |
66 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.21652694 |
67 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.21441942 |
68 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.20911550 |
69 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.20815335 |
70 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.20639681 |
71 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.19337715 |
72 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.17870425 |
73 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.17573233 |
74 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.17097121 |
75 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.14856693 |
76 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.13419844 |
77 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.13176070 |
78 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.11014347 |
79 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.09856630 |
80 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.09716641 |
81 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.09467478 |
82 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.08157270 |
83 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.07450350 |
84 | KDM2B_26808549_Chip-Seq_REH_Human | 1.07093841 |
85 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.06769997 |
86 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.06441292 |
87 | * MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.06202547 |
88 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04526800 |
89 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.04335318 |
90 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.04149433 |
91 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.02882742 |
92 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.02133897 |
93 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.01929127 |
94 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.01853660 |
95 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.01125963 |
96 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.00674923 |
97 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.00272271 |
98 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.00245992 |
99 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.00134396 |
100 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.99820485 |
101 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.99726582 |
102 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.99074787 |
103 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.99048756 |
104 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98307532 |
105 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.97900176 |
106 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.97755836 |
107 | RXR_22108803_ChIP-Seq_LS180_Human | 0.96819234 |
108 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.95816358 |
109 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.94661929 |
110 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.93161208 |
111 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.93044011 |
112 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.92979136 |
113 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.92977676 |
114 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92349296 |
115 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.88920039 |
116 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.88506417 |
117 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.87292751 |
118 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.87268499 |
119 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.86846382 |
120 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.85731503 |
121 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.85144532 |
122 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.84407120 |
123 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.83262631 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 8.95475420 |
2 | MP0005275_abnormal_skin_tensile | 5.64291403 |
3 | MP0005503_abnormal_tendon_morphology | 4.91572769 |
4 | MP0003705_abnormal_hypodermis_morpholog | 3.94025494 |
5 | MP0004272_abnormal_basement_membrane | 3.50313885 |
6 | MP0003279_aneurysm | 3.36643462 |
7 | MP0001958_emphysema | 3.30651519 |
8 | MP0009384_cardiac_valve_regurgitation | 2.78447921 |
9 | MP0000013_abnormal_adipose_tissue | 2.53151497 |
10 | MP0005623_abnormal_meninges_morphology | 2.41546541 |
11 | MP0005670_abnormal_white_adipose | 2.32180695 |
12 | MP0006054_spinal_hemorrhage | 2.02983564 |
13 | MP0010368_abnormal_lymphatic_system | 2.01882120 |
14 | MP0005508_abnormal_skeleton_morphology | 1.96641406 |
15 | MP0002295_abnormal_pulmonary_circulatio | 1.93694416 |
16 | MP0002060_abnormal_skin_morphology | 1.92781923 |
17 | MP0005666_abnormal_adipose_tissue | 1.81471988 |
18 | MP0002837_dystrophic_cardiac_calcinosis | 1.79110183 |
19 | MP0002108_abnormal_muscle_morphology | 1.78014119 |
20 | MP0005375_adipose_tissue_phenotype | 1.72618241 |
21 | MP0001879_abnormal_lymphatic_vessel | 1.70720925 |
22 | MP0000003_abnormal_adipose_tissue | 1.70302118 |
23 | MP0004185_abnormal_adipocyte_glucose | 1.70095101 |
24 | MP0004130_abnormal_muscle_cell | 1.68294048 |
25 | MP0003566_abnormal_cell_adhesion | 1.65271552 |
26 | MP0005257_abnormal_intraocular_pressure | 1.56420477 |
27 | MP0010386_abnormal_urinary_bladder | 1.47615901 |
28 | MP0003385_abnormal_body_wall | 1.43270283 |
29 | MP0000751_myopathy | 1.41935135 |
30 | MP0003091_abnormal_cell_migration | 1.40819733 |
31 | MP0009250_abnormal_appendicular_skeleto | 1.37499198 |
32 | MP0003045_fibrosis | 1.31332524 |
33 | MP0003724_increased_susceptibility_to | 1.28565406 |
34 | MP0002896_abnormal_bone_mineralization | 1.28129996 |
35 | MP0005023_abnormal_wound_healing | 1.26405043 |
36 | MP0004145_abnormal_muscle_electrophysio | 1.25228195 |
37 | MP0000767_abnormal_smooth_muscle | 1.20763181 |
38 | MP0003941_abnormal_skin_development | 1.18986434 |
39 | MP0002168_other_aberrant_phenotype | 1.18175779 |
40 | MP0004134_abnormal_chest_morphology | 1.17634647 |
41 | MP0001299_abnormal_eye_distance/ | 1.14274322 |
42 | MP0001243_abnormal_dermal_layer | 1.14141191 |
43 | MP0000733_abnormal_muscle_development | 1.13400201 |
44 | MP0001542_abnormal_bone_strength | 1.09226669 |
45 | MP0003283_abnormal_digestive_organ | 1.09156479 |
46 | * MP0005390_skeleton_phenotype | 1.08925345 |
47 | MP0003942_abnormal_urinary_system | 1.07427333 |
48 | MP0002282_abnormal_trachea_morphology | 1.06786791 |
49 | * MP0000163_abnormal_cartilage_morphology | 1.05881542 |
50 | MP0002115_abnormal_skeleton_extremities | 1.05573602 |
51 | MP0000750_abnormal_muscle_regeneration | 1.02833359 |
52 | MP0009780_abnormal_chondrocyte_physiolo | 1.01242630 |
53 | MP0010030_abnormal_orbit_morphology | 1.01117337 |
54 | MP0005595_abnormal_vascular_smooth | 0.98812294 |
55 | MP0005171_absent_coat_pigmentation | 0.97534397 |
56 | MP0001661_extended_life_span | 0.97100379 |
57 | MP0002998_abnormal_bone_remodeling | 0.93606294 |
58 | MP0009115_abnormal_fat_cell | 0.93498431 |
59 | MP0000534_abnormal_ureter_morphology | 0.93199707 |
60 | MP0002254_reproductive_system_inflammat | 0.90973488 |
61 | MP0010352_gastrointestinal_tract_polyps | 0.90628302 |
62 | MP0003115_abnormal_respiratory_system | 0.90287876 |
63 | MP0003448_altered_tumor_morphology | 0.89788347 |
64 | MP0003828_pulmonary_edema | 0.88862400 |
65 | MP0003300_gastrointestinal_ulcer | 0.87988710 |
66 | MP0000538_abnormal_urinary_bladder | 0.87385604 |
67 | MP0006138_congestive_heart_failure | 0.87069178 |
68 | MP0002113_abnormal_skeleton_development | 0.86666106 |
69 | * MP0002933_joint_inflammation | 0.85878923 |
70 | MP0000759_abnormal_skeletal_muscle | 0.85654732 |
71 | MP0002249_abnormal_larynx_morphology | 0.85195995 |
72 | MP0005388_respiratory_system_phenotype | 0.85058600 |
73 | MP0002133_abnormal_respiratory_system | 0.85058600 |
74 | MP0002128_abnormal_blood_circulation | 0.84824832 |
75 | MP0002932_abnormal_joint_morphology | 0.84508487 |
76 | MP0000747_muscle_weakness | 0.84438987 |
77 | MP0000762_abnormal_tongue_morphology | 0.84284520 |
78 | MP0000428_abnormal_craniofacial_morphol | 0.82147174 |
79 | MP0009053_abnormal_anal_canal | 0.81487726 |
80 | MP0003959_abnormal_lean_body | 0.80885206 |
81 | MP0004084_abnormal_cardiac_muscle | 0.78010616 |
82 | MP0004036_abnormal_muscle_relaxation | 0.77442237 |
83 | MP0004233_abnormal_muscle_weight | 0.76991651 |
84 | MP0001614_abnormal_blood_vessel | 0.74815723 |
85 | MP0005076_abnormal_cell_differentiation | 0.73813200 |
86 | MP0004087_abnormal_muscle_fiber | 0.73412246 |
87 | MP0005164_abnormal_response_to | 0.72850964 |
88 | MP0000749_muscle_degeneration | 0.72737835 |
89 | * MP0001533_abnormal_skeleton_physiology | 0.72204652 |
90 | MP0002971_abnormal_brown_adipose | 0.71801482 |
91 | MP0002234_abnormal_pharynx_morphology | 0.71695348 |
92 | MP0001177_atelectasis | 0.71377840 |
93 | MP0004858_abnormal_nervous_system | 0.70760992 |
94 | MP0000432_abnormal_head_morphology | 0.68047161 |
95 | MP0005197_abnormal_uvea_morphology | 0.67875601 |
96 | MP0000462_abnormal_digestive_system | 0.67332924 |
97 | MP0000343_altered_response_to | 0.66039938 |
98 | MP0003950_abnormal_plasma_membrane | 0.64130201 |
99 | MP0002269_muscular_atrophy | 0.63189367 |
100 | MP0002089_abnormal_postnatal_growth/wei | 0.63152683 |
101 | MP0008775_abnormal_heart_ventricle | 0.62985971 |
102 | MP0004883_abnormal_blood_vessel | 0.62557585 |
103 | MP0002114_abnormal_axial_skeleton | 0.61671461 |
104 | MP0001175_abnormal_lung_morphology | 0.61458908 |
105 | MP0002106_abnormal_muscle_physiology | 0.61215482 |
106 | MP0003795_abnormal_bone_structure | 0.61136360 |
107 | MP0000049_abnormal_middle_ear | 0.60717856 |
108 | MP0005620_abnormal_muscle_contractility | 0.60308695 |
109 | MP0003191_abnormal_cellular_cholesterol | 0.59819407 |
110 | MP0009379_abnormal_foot_pigmentation | 0.59752445 |
111 | MP0001544_abnormal_cardiovascular_syste | 0.59490889 |
112 | MP0005385_cardiovascular_system_phenoty | 0.59490889 |
113 | MP0001881_abnormal_mammary_gland | 0.59363218 |
114 | MP0005367_renal/urinary_system_phenotyp | 0.59127917 |
115 | MP0000516_abnormal_urinary_system | 0.59127917 |
116 | MP0001348_abnormal_lacrimal_gland | 0.58922623 |
117 | MP0002166_altered_tumor_susceptibility | 0.58443934 |
118 | MP0003755_abnormal_palate_morphology | 0.58059368 |
119 | MP0005369_muscle_phenotype | 0.57590203 |
120 | MP0000230_abnormal_systemic_arterial | 0.56098902 |
121 | MP0002233_abnormal_nose_morphology | 0.53044998 |
122 | MP0003935_abnormal_craniofacial_develop | 0.51904531 |
123 | MP0002116_abnormal_craniofacial_bone | 0.51693736 |
124 | MP0000467_abnormal_esophagus_morphology | 0.50292903 |
125 | MP0001849_ear_inflammation | 0.48890195 |
126 | MP0001270_distended_abdomen | 0.47256762 |
127 | * MP0002109_abnormal_limb_morphology | 0.46851389 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 8.95614388 |
2 | Premature rupture of membranes (HP:0001788) | 7.95173621 |
3 | Aortic dissection (HP:0002647) | 5.38894136 |
4 | Ankle contracture (HP:0006466) | 5.35651180 |
5 | Broad metatarsal (HP:0001783) | 5.15396241 |
6 | Aortic aneurysm (HP:0004942) | 4.98042454 |
7 | Soft skin (HP:0000977) | 4.97956134 |
8 | Shallow orbits (HP:0000586) | 4.75134147 |
9 | Cervical subluxation (HP:0003308) | 4.32920398 |
10 | Cerebral aneurysm (HP:0004944) | 4.29148648 |
11 | Dilatation of the ascending aorta (HP:0005111) | 4.18120854 |
12 | Peritonitis (HP:0002586) | 4.12410916 |
13 | Atrophic scars (HP:0001075) | 4.07197211 |
14 | Bladder diverticulum (HP:0000015) | 3.97434429 |
15 | Popliteal pterygium (HP:0009756) | 3.91099350 |
16 | Wrist flexion contracture (HP:0001239) | 3.78543405 |
17 | Fragile skin (HP:0001030) | 3.73180035 |
18 | Vertebral compression fractures (HP:0002953) | 3.70113999 |
19 | Follicular hyperkeratosis (HP:0007502) | 3.67400081 |
20 | Type 2 muscle fiber atrophy (HP:0003554) | 3.62415069 |
21 | Abnormality of dentin (HP:0010299) | 3.61583354 |
22 | Increased connective tissue (HP:0009025) | 3.59288322 |
23 | Mitral valve prolapse (HP:0001634) | 3.52456500 |
24 | Vascular tortuosity (HP:0004948) | 3.46874948 |
25 | Type 1 muscle fiber predominance (HP:0003803) | 3.43330421 |
26 | Spinal rigidity (HP:0003306) | 3.42476296 |
27 | Wormian bones (HP:0002645) | 3.40700706 |
28 | Neonatal short-limb short stature (HP:0008921) | 3.34946793 |
29 | Biconcave vertebral bodies (HP:0004586) | 3.33716570 |
30 | Genu recurvatum (HP:0002816) | 3.33640081 |
31 | Blue sclerae (HP:0000592) | 3.29158544 |
32 | Overgrowth (HP:0001548) | 3.23790625 |
33 | Muscle fiber atrophy (HP:0100295) | 3.15605397 |
34 | Abnormality of the neuromuscular junction (HP:0003398) | 3.01734944 |
35 | Fatigable weakness (HP:0003473) | 3.01734944 |
36 | Hyperextensible skin (HP:0000974) | 2.88634194 |
37 | Increased variability in muscle fiber diameter (HP:0003557) | 2.87851106 |
38 | Mitral stenosis (HP:0001718) | 2.84317589 |
39 | Arterial tortuosity (HP:0005116) | 2.79860660 |
40 | Aneurysm (HP:0002617) | 2.79363110 |
41 | Bowel diverticulosis (HP:0005222) | 2.73498640 |
42 | Ovoid vertebral bodies (HP:0003300) | 2.68082783 |
43 | Slender build (HP:0001533) | 2.66147928 |
44 | Aortic valve stenosis (HP:0001650) | 2.65155705 |
45 | Joint laxity (HP:0001388) | 2.60665613 |
46 | Ectopia lentis (HP:0001083) | 2.58787869 |
47 | Bell-shaped thorax (HP:0001591) | 2.55823626 |
48 | Gowers sign (HP:0003391) | 2.54138729 |
49 | Abnormal delivery (HP:0001787) | 2.53877947 |
50 | Infantile muscular hypotonia (HP:0008947) | 2.47858847 |
51 | Abnormality of the acetabulum (HP:0003170) | 2.47661038 |
52 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.47517881 |
53 | Venous abnormality (HP:0002624) | 2.46927488 |
54 | Thin bony cortex (HP:0002753) | 2.44697267 |
55 | Wide anterior fontanel (HP:0000260) | 2.42941051 |
56 | Buphthalmos (HP:0000557) | 2.42751777 |
57 | Venous insufficiency (HP:0005293) | 2.41597543 |
58 | Decreased muscle mass (HP:0003199) | 2.41420820 |
59 | Hypoplastic ischia (HP:0003175) | 2.40566980 |
60 | Keratoconus (HP:0000563) | 2.39523153 |
61 | Increased corneal curvature (HP:0100692) | 2.39523153 |
62 | Elbow flexion contracture (HP:0002987) | 2.38228502 |
63 | Weak cry (HP:0001612) | 2.35276014 |
64 | Nonimmune hydrops fetalis (HP:0001790) | 2.33635910 |
65 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.33138515 |
66 | Hypoplasia of the iris (HP:0007676) | 2.32479836 |
67 | Camptodactyly of toe (HP:0001836) | 2.31565269 |
68 | Mitral regurgitation (HP:0001653) | 2.30516840 |
69 | Muscle fiber splitting (HP:0003555) | 2.30324493 |
70 | Acanthosis nigricans (HP:0000956) | 2.26632188 |
71 | Easy fatigability (HP:0003388) | 2.26363901 |
72 | Striae distensae (HP:0001065) | 2.25931801 |
73 | Amniotic constriction ring (HP:0009775) | 2.24940798 |
74 | Abnormality of placental membranes (HP:0011409) | 2.24940798 |
75 | Osteolytic defects of the hand bones (HP:0009699) | 2.24812985 |
76 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.24812985 |
77 | Round ear (HP:0100830) | 2.22645179 |
78 | Broad ribs (HP:0000885) | 2.20996601 |
79 | Osteoarthritis (HP:0002758) | 2.20354246 |
80 | Aplasia of the musculature (HP:0100854) | 2.19997602 |
81 | Syringomyelia (HP:0003396) | 2.19610275 |
82 | Spinal cord lesions (HP:0100561) | 2.19610275 |
83 | Knee flexion contracture (HP:0006380) | 2.19176513 |
84 | Abnormality of the ischium (HP:0003174) | 2.18883338 |
85 | Spondylolisthesis (HP:0003302) | 2.18250795 |
86 | Abnormality of the anterior chamber (HP:0000593) | 2.13526532 |
87 | Pterygium (HP:0001059) | 2.09496329 |
88 | Absent phalangeal crease (HP:0006109) | 2.07864333 |
89 | Microglossia (HP:0000171) | 2.06225489 |
90 | Coxa vara (HP:0002812) | 2.04471035 |
91 | Hip contracture (HP:0003273) | 2.03163415 |
92 | Abnormal finger flexion creases (HP:0006143) | 2.00789401 |
93 | Mesangial abnormality (HP:0001966) | 1.99801415 |
94 | Abnormality of the peritoneum (HP:0002585) | 1.98614685 |
95 | Oligomenorrhea (HP:0000876) | 1.97516276 |
96 | Cardiovascular calcification (HP:0011915) | 1.96826976 |
97 | Osteopenia (HP:0000938) | 1.96761342 |
98 | Thin ribs (HP:0000883) | 1.96423924 |
99 | Nemaline bodies (HP:0003798) | 1.96232589 |
100 | Lymphangioma (HP:0100764) | 1.94607000 |
101 | Inguinal hernia (HP:0000023) | 1.94038463 |
102 | Tibial bowing (HP:0002982) | 1.92535881 |
103 | Breech presentation (HP:0001623) | 1.92451142 |
104 | Congenital glaucoma (HP:0001087) | 1.91713420 |
105 | Mesomelia (HP:0003027) | 1.91133943 |
106 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.90308529 |
107 | Corneal dystrophy (HP:0001131) | 1.89024942 |
108 | Short nail (HP:0001799) | 1.88889286 |
109 | Pulmonary artery stenosis (HP:0004415) | 1.87270999 |
110 | Aortic regurgitation (HP:0001659) | 1.86701714 |
111 | Mild short stature (HP:0003502) | 1.84986353 |
112 | Disproportionate tall stature (HP:0001519) | 1.84078884 |
113 | Deviation of the hallux (HP:0010051) | 1.83645085 |
114 | Coronal craniosynostosis (HP:0004440) | 1.80708650 |
115 | Scapular winging (HP:0003691) | 1.79381409 |
116 | Joint stiffness (HP:0001387) | 1.79021773 |
117 | Joint contractures involving the joints of the feet (HP:0100492) | 1.79009158 |
118 | Flexion contracture of toe (HP:0005830) | 1.79009158 |
119 | Thin skin (HP:0000963) | 1.78728363 |
120 | Difficulty running (HP:0009046) | 1.78368752 |
121 | Spinal cord compression (HP:0002176) | 1.78194113 |
122 | Asymmetry of the thorax (HP:0001555) | 1.77907636 |
123 | Flat cornea (HP:0007720) | 1.76852421 |
124 | Hallux valgus (HP:0001822) | 1.76418799 |
125 | Delayed gross motor development (HP:0002194) | 1.75829317 |
126 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.75643217 |
127 | Absent frontal sinuses (HP:0002688) | 1.74714606 |
128 | Limited hip movement (HP:0008800) | 1.72901170 |
129 | Hypoventilation (HP:0002791) | 1.71927929 |
130 | Broad long bones (HP:0005622) | 1.70666465 |
131 | Generalized amyotrophy (HP:0003700) | 1.70108965 |
132 | Platyspondyly (HP:0000926) | 1.70037762 |
133 | Protruding ear (HP:0000411) | 1.69035252 |
134 | Lipoatrophy (HP:0100578) | 1.68067640 |
135 | Decreased skull ossification (HP:0004331) | 1.66337351 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MUSK | 9.38844698 |
2 | DDR2 | 5.04685037 |
3 | TRIB3 | 4.42635003 |
4 | SIK1 | 3.36022199 |
5 | TTN | 3.35078742 |
6 | PDGFRA | 3.33552435 |
7 | EPHB2 | 2.91368838 |
8 | LATS1 | 2.87478417 |
9 | CAMK1D | 2.79680164 |
10 | TGFBR2 | 2.62262470 |
11 | LATS2 | 2.50569723 |
12 | ERN1 | 2.44512988 |
13 | AKT3 | 2.35995686 |
14 | FER | 2.33152403 |
15 | RIPK1 | 2.12213717 |
16 | CAMK1G | 2.06553885 |
17 | KDR | 1.98990536 |
18 | TIE1 | 1.96645139 |
19 | PKN2 | 1.82226718 |
20 | FRK | 1.79622544 |
21 | PIK3CA | 1.77601040 |
22 | MYLK | 1.69808532 |
23 | EPHA3 | 1.66065508 |
24 | PAK2 | 1.60716375 |
25 | PTK2B | 1.43449659 |
26 | TRPM7 | 1.39189927 |
27 | NEK9 | 1.38606093 |
28 | DMPK | 1.34838917 |
29 | PTK6 | 1.20603187 |
30 | MAP3K12 | 1.20134539 |
31 | PDGFRB | 1.19663790 |
32 | JAK1 | 1.15598472 |
33 | TAF1 | 1.15422702 |
34 | FGFR3 | 1.15154818 |
35 | LMTK2 | 1.14531599 |
36 | ROCK1 | 1.14052459 |
37 | PAK3 | 1.11490934 |
38 | PDK4 | 1.09963995 |
39 | PDK3 | 1.09963995 |
40 | FGFR2 | 1.09666390 |
41 | STK3 | 1.03986644 |
42 | PTK2 | 1.03383589 |
43 | WNK4 | 0.98753905 |
44 | PAK4 | 0.97709497 |
45 | GRK5 | 0.96115629 |
46 | BMX | 0.95478737 |
47 | WNK1 | 0.94252631 |
48 | MTOR | 0.90155325 |
49 | MET | 0.89994125 |
50 | FGFR1 | 0.89636452 |
51 | PBK | 0.86054189 |
52 | EPHB1 | 0.84235176 |
53 | PAK6 | 0.83715178 |
54 | ERBB4 | 0.83598655 |
55 | MELK | 0.82491383 |
56 | MAP2K1 | 0.81691234 |
57 | PDK2 | 0.81381977 |
58 | PRKD2 | 0.81307375 |
59 | GRK7 | 0.78958677 |
60 | ILK | 0.78198627 |
61 | MAPK7 | 0.78147125 |
62 | TGFBR1 | 0.75867251 |
63 | LRRK2 | 0.75053489 |
64 | PRKD3 | 0.74416370 |
65 | STK38 | 0.74179714 |
66 | PRKCH | 0.73804022 |
67 | MAP3K6 | 0.72729332 |
68 | STK38L | 0.72609493 |
69 | PRKD1 | 0.71864074 |
70 | PRKAA2 | 0.69640435 |
71 | MAP3K3 | 0.67729851 |
72 | ERBB3 | 0.67636649 |
73 | CDK8 | 0.67025430 |
74 | RET | 0.66997304 |
75 | NUAK1 | 0.65699271 |
76 | MARK2 | 0.64973670 |
77 | MAP3K7 | 0.61647159 |
78 | INSR | 0.61594908 |
79 | MST1R | 0.61546105 |
80 | FGFR4 | 0.61429517 |
81 | MARK1 | 0.59606978 |
82 | ROCK2 | 0.58878742 |
83 | MOS | 0.57903054 |
84 | MAPKAPK5 | 0.57095870 |
85 | BCKDK | 0.56551290 |
86 | NTRK1 | 0.55920204 |
87 | CDK9 | 0.53853594 |
88 | PNCK | 0.52221161 |
89 | RPS6KA4 | 0.52173433 |
90 | LIMK1 | 0.51987246 |
91 | PIM2 | 0.51576833 |
92 | TYK2 | 0.51479247 |
93 | IGF1R | 0.51464485 |
94 | STK39 | 0.50969403 |
95 | KIT | 0.50476435 |
96 | SRC | 0.49885649 |
97 | GRK1 | 0.49137515 |
98 | MAPKAPK3 | 0.48337128 |
99 | ADRBK1 | 0.48239664 |
100 | PLK2 | 0.48031724 |
101 | ICK | 0.47080003 |
102 | CAMKK2 | 0.46968155 |
103 | SGK2 | 0.46647691 |
104 | ABL2 | 0.46593193 |
105 | OBSCN | 0.45022427 |
106 | NLK | 0.45003335 |
107 | CDK6 | 0.44457190 |
108 | GSK3A | 0.42016577 |
109 | SGK3 | 0.41185631 |
110 | PRKG2 | 0.41008069 |
111 | PHKG1 | 0.40249344 |
112 | PHKG2 | 0.40249344 |
113 | EIF2AK3 | 0.39332830 |
114 | PIK3CG | 0.39062001 |
115 | MAP3K10 | 0.38733067 |
116 | CAMK2G | 0.37921232 |
117 | PRKCE | 0.37649619 |
118 | JAK3 | 0.36742176 |
119 | FLT3 | 0.35407445 |
120 | IRAK1 | 0.32976846 |
121 | CAMK2D | 0.32946976 |
122 | CSK | 0.29780521 |
123 | RPS6KA2 | 0.28628678 |
124 | MAPK4 | 0.28563895 |
125 | RPS6KB1 | 0.27196280 |
126 | PRKG1 | 0.27136597 |
127 | CAMK2B | 0.26878458 |
128 | CAMK4 | 0.25665086 |
129 | SGK494 | 0.24899776 |
130 | SGK223 | 0.24899776 |
131 | EEF2K | 0.23897252 |
132 | TESK1 | 0.23114046 |
133 | MAPKAPK2 | 0.22962142 |
134 | CDC42BPA | 0.22043505 |
135 | ABL1 | 0.21714812 |
136 | MAPK1 | 0.21478442 |
137 | INSRR | 0.19939734 |
138 | DAPK3 | 0.18214353 |
139 | ZAK | 0.18050096 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 4.61777644 |
2 | Focal adhesion_Homo sapiens_hsa04510 | 3.21566556 |
3 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 3.12180304 |
4 | Protein digestion and absorption_Homo sapiens_hsa04974 | 2.73107833 |
5 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 2.36563157 |
6 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.31440588 |
7 | Amoebiasis_Homo sapiens_hsa05146 | 2.25851462 |
8 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.18412605 |
9 | Malaria_Homo sapiens_hsa05144 | 2.14146666 |
10 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 2.07464551 |
11 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.99948631 |
12 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.97931476 |
13 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.96202479 |
14 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.90984954 |
15 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.84658812 |
16 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.82022286 |
17 | Adherens junction_Homo sapiens_hsa04520 | 1.74243705 |
18 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.70143530 |
19 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.63023305 |
20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.55724279 |
21 | Melanoma_Homo sapiens_hsa05218 | 1.47340254 |
22 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.43098306 |
23 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.37210674 |
24 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.34521407 |
25 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.32233453 |
26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.31325631 |
27 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.30609645 |
28 | Viral myocarditis_Homo sapiens_hsa05416 | 1.28604167 |
29 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.21941870 |
30 | Bladder cancer_Homo sapiens_hsa05219 | 1.21831947 |
31 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.14968505 |
32 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.13725718 |
33 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.11815124 |
34 | Pathways in cancer_Homo sapiens_hsa05200 | 1.07596604 |
35 | Axon guidance_Homo sapiens_hsa04360 | 1.06399342 |
36 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.05582856 |
37 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.04373067 |
38 | Platelet activation_Homo sapiens_hsa04611 | 1.03124292 |
39 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.02427959 |
40 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.01631391 |
41 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.00377859 |
42 | Insulin resistance_Homo sapiens_hsa04931 | 0.99736461 |
43 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.94344527 |
44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.91187086 |
45 | Glioma_Homo sapiens_hsa05214 | 0.90568686 |
46 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.90514722 |
47 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.88974394 |
48 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.88647130 |
49 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.88014529 |
50 | ABC transporters_Homo sapiens_hsa02010 | 0.87603351 |
51 | Prostate cancer_Homo sapiens_hsa05215 | 0.87431756 |
52 | Pertussis_Homo sapiens_hsa05133 | 0.86779050 |
53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.86747798 |
54 | Tight junction_Homo sapiens_hsa04530 | 0.85756036 |
55 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.85217546 |
56 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.83729313 |
57 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.80939313 |
58 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.79668652 |
59 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.79447865 |
60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.76855597 |
61 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.75385789 |
62 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.74437517 |
63 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.73939469 |
64 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72892629 |
65 | Long-term depression_Homo sapiens_hsa04730 | 0.72080761 |
66 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.71171297 |
67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.67322086 |
68 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.66851654 |
69 | Melanogenesis_Homo sapiens_hsa04916 | 0.66721746 |
70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.66577469 |
71 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.66406758 |
72 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.65716368 |
73 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.64013478 |
74 | Phagosome_Homo sapiens_hsa04145 | 0.61982817 |
75 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.61887029 |
76 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.61870773 |
77 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.61126446 |
78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.60963413 |
79 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.60679374 |
80 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.58618734 |
81 | Renin secretion_Homo sapiens_hsa04924 | 0.57228592 |
82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.56536654 |
83 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56056570 |
84 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.54893026 |
85 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.54810572 |
86 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.51852533 |
87 | Shigellosis_Homo sapiens_hsa05131 | 0.51586723 |
88 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.51395276 |
89 | Endocytosis_Homo sapiens_hsa04144 | 0.51363193 |
90 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.50399788 |
91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.49202185 |
92 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.49102865 |
93 | Gap junction_Homo sapiens_hsa04540 | 0.48726283 |
94 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.47988751 |
95 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.46210087 |
96 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.46204073 |
97 | Lysosome_Homo sapiens_hsa04142 | 0.45560937 |
98 | Cocaine addiction_Homo sapiens_hsa05030 | 0.45070029 |
99 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44959509 |
100 | Colorectal cancer_Homo sapiens_hsa05210 | 0.44188696 |
101 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.44044102 |
102 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43524583 |
103 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42254331 |
104 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.42120973 |
105 | Endometrial cancer_Homo sapiens_hsa05213 | 0.41760621 |
106 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.41183384 |
107 | Prion diseases_Homo sapiens_hsa05020 | 0.40443656 |
108 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.39884482 |
109 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.37621268 |
110 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.37579301 |
111 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.37459876 |
112 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.37350597 |
113 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36629194 |
114 | Hepatitis B_Homo sapiens_hsa05161 | 0.35821124 |
115 | Salmonella infection_Homo sapiens_hsa05132 | 0.35820654 |
116 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.35363711 |
117 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.35348786 |
118 | Other glycan degradation_Homo sapiens_hsa00511 | 0.34590958 |
119 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.33998680 |
120 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.33435927 |
121 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.32909290 |
122 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32293501 |
123 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.32282807 |
124 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26183969 |
125 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.25620515 |