ADAMTSL5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)8.05683099
2plasma membrane repair (GO:0001778)6.96544453
3cardiac myofibril assembly (GO:0055003)6.92254236
4actin-myosin filament sliding (GO:0033275)6.54428259
5muscle filament sliding (GO:0030049)6.54428259
6myofibril assembly (GO:0030239)6.44465601
7regulation of skeletal muscle contraction (GO:0014819)6.24738843
8positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.06092763
9negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.59361283
10actin-mediated cell contraction (GO:0070252)5.50668037
11regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.26359449
12cardiac muscle cell development (GO:0055013)5.22909450
13regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.17407142
14cardiac muscle contraction (GO:0060048)5.16576613
15actomyosin structure organization (GO:0031032)5.10257153
16regulation of relaxation of muscle (GO:1901077)5.01278953
17negative regulation of potassium ion transmembrane transport (GO:1901380)4.96904386
18bundle of His cell to Purkinje myocyte communication (GO:0086069)4.96809654
19cardiac cell development (GO:0055006)4.95381075
20regulation of actin filament-based movement (GO:1903115)4.77751428
21cardiac muscle tissue morphogenesis (GO:0055008)4.57225164
22regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)4.52482575
23ventricular cardiac muscle cell action potential (GO:0086005)4.36724703
24ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.34248670
25sarcoplasmic reticulum calcium ion transport (GO:0070296)4.33462778
26actin filament-based movement (GO:0030048)4.29824830
27striated muscle contraction (GO:0006941)4.25050565
28adult heart development (GO:0007512)4.23388737
29cardiac muscle hypertrophy (GO:0003300)4.17639621
30regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.15432619
31muscle tissue morphogenesis (GO:0060415)4.13952864
32heart trabecula formation (GO:0060347)4.12280921
33regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.07454383
34tricarboxylic acid cycle (GO:0006099)4.03686742
35striated muscle hypertrophy (GO:0014897)4.00599420
36regulation of striated muscle contraction (GO:0006942)3.97846829
37regulation of cell communication by electrical coupling (GO:0010649)3.87878435
38carnitine shuttle (GO:0006853)3.84084680
39muscle hypertrophy (GO:0014896)3.80946732
40type B pancreatic cell proliferation (GO:0044342)3.77054530
41protein heterotrimerization (GO:0070208)3.63148315
42skin morphogenesis (GO:0043589)3.59414644
43heart contraction (GO:0060047)3.59229973
44heart process (GO:0003015)3.59229973
45regulation of the force of heart contraction (GO:0002026)3.48531221
46skeletal muscle adaptation (GO:0043501)3.45540922
47response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.41624360
48endocardial cushion development (GO:0003197)3.40928331
49regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.40132674
50positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.39046852
51regulation of p38MAPK cascade (GO:1900744)3.36663321
52fatty acid transmembrane transport (GO:1902001)3.35957160
53regulation of sarcomere organization (GO:0060297)3.33658995
54cell communication involved in cardiac conduction (GO:0086065)3.32051722
55skeletal muscle contraction (GO:0003009)3.31938104
56striated muscle atrophy (GO:0014891)3.30713673
57regulation of cardiac muscle cell contraction (GO:0086004)3.26180576
58regulation of cardioblast differentiation (GO:0051890)3.26128169
59desmosome organization (GO:0002934)3.25887831
60response to muscle activity (GO:0014850)3.25224447
61cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.24964069
62actin filament depolymerization (GO:0030042)3.24514923
63regulation of cardiac muscle contraction (GO:0055117)3.23705987
64muscle contraction (GO:0006936)3.22574329
65oxygen transport (GO:0015671)3.13190063
66positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.12693757
67creatine metabolic process (GO:0006600)3.11261199
68striated muscle cell development (GO:0055002)3.11116425
69regulation of sequestering of triglyceride (GO:0010889)3.09856216
70trabecula formation (GO:0060343)3.09535790
71regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.08826163
72muscle system process (GO:0003012)3.05441004
73regulation of membrane repolarization (GO:0060306)3.04505608
74regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.02934833
75muscle cell cellular homeostasis (GO:0046716)2.98504150
76collagen fibril organization (GO:0030199)2.98380026
77regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.97570249
78regulation of acyl-CoA biosynthetic process (GO:0050812)2.93804089
79striated muscle adaptation (GO:0014888)2.93677820
80regulation of ATP catabolic process (GO:1903289)2.93339146
81regulation of ATPase activity (GO:0043462)2.93339146
82negative regulation of nitric-oxide synthase activity (GO:0051001)2.93252561
83negative regulation of protein localization to cell surface (GO:2000009)2.92760673
84carnitine transmembrane transport (GO:1902603)2.92653440
85extracellular matrix assembly (GO:0085029)2.92039202
86negative regulation of striated muscle cell apoptotic process (GO:0010664)2.91593260
87positive regulation of cation channel activity (GO:2001259)2.91240299
88atrioventricular valve morphogenesis (GO:0003181)2.90990246
89extracellular fibril organization (GO:0043206)2.89356815
90regulation of heart rate (GO:0002027)2.89297421
91positive regulation of heart contraction (GO:0045823)2.88427603
92muscle adaptation (GO:0043500)2.88194526
93relaxation of cardiac muscle (GO:0055119)2.88110707
94sphingosine metabolic process (GO:0006670)2.87630478
95negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.87478234
96negative regulation of cardiac muscle tissue growth (GO:0055022)2.86628973
97negative regulation of heart growth (GO:0061117)2.86628973
98regulation of heart contraction (GO:0008016)2.86328845
99vascular endothelial growth factor signaling pathway (GO:0038084)2.86201155
100cell migration involved in heart development (GO:0060973)2.85661695
101fibroblast migration (GO:0010761)2.85369116
102cardiac muscle cell action potential (GO:0086001)2.85177435
103proline biosynthetic process (GO:0006561)2.85097030
104cell-substrate junction assembly (GO:0007044)2.84780508
105regulation of tight junction assembly (GO:2000810)2.84713876
106cardiac muscle cell action potential involved in contraction (GO:0086002)2.83771435
107regulation of muscle contraction (GO:0006937)2.82730334
108regulation of integrin activation (GO:0033623)2.82271739
109epithelial cell-cell adhesion (GO:0090136)2.80761601
110hemidesmosome assembly (GO:0031581)2.79732712
111negative regulation of cell size (GO:0045792)2.79561393
112positive regulation of myotube differentiation (GO:0010831)2.77874342
113cardiac muscle hypertrophy in response to stress (GO:0014898)2.77308967
114muscle hypertrophy in response to stress (GO:0003299)2.77308967
115cardiac muscle adaptation (GO:0014887)2.77308967
116response to inactivity (GO:0014854)2.75382494
117kidney mesenchyme development (GO:0072074)2.75348152
118muscle atrophy (GO:0014889)2.75329350
119sequestering of extracellular ligand from receptor (GO:0035581)2.71422188
120cell-substrate adherens junction assembly (GO:0007045)2.71069876
121focal adhesion assembly (GO:0048041)2.71069876
122COPI coating of Golgi vesicle (GO:0048205)2.69064172
123Golgi transport vesicle coating (GO:0048200)2.69064172
124positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.67343311
125negative regulation of chondrocyte differentiation (GO:0032331)2.65773967
126protein hydroxylation (GO:0018126)2.65460993
127sphingoid metabolic process (GO:0046519)2.64133001
128glomerular basement membrane development (GO:0032836)2.63230052
129negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.63092791
130smooth muscle tissue development (GO:0048745)2.61601508
131pericardium development (GO:0060039)2.58880874
132fibril organization (GO:0097435)2.58781325
133basement membrane organization (GO:0071711)2.57130069
134diol metabolic process (GO:0034311)2.56885635
135embryonic skeletal joint morphogenesis (GO:0060272)2.51032501
136endothelial cell morphogenesis (GO:0001886)2.50681713
137cell adhesion mediated by integrin (GO:0033627)2.47610211
138NADH metabolic process (GO:0006734)2.46763249
139negative regulation of digestive system process (GO:0060457)2.46214277
140ventricular cardiac muscle cell development (GO:0055015)2.45987450
141negative regulation of peptidyl-serine phosphorylation (GO:0033137)2.44808748
142muscle organ development (GO:0007517)2.43753820
143virion attachment to host cell (GO:0019062)2.43459750
144adhesion of symbiont to host cell (GO:0044650)2.43459750
145regulation of integrin-mediated signaling pathway (GO:2001044)2.42631098
146muscle structure development (GO:0061061)2.39868464
147skeletal muscle tissue development (GO:0007519)2.36280168
148outflow tract septum morphogenesis (GO:0003148)2.35145599
149regulation of fatty acid oxidation (GO:0046320)2.32466588
150endodermal cell differentiation (GO:0035987)2.32217977

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RARG_19884340_ChIP-ChIP_MEFs_Mouse4.48730015
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.39673287
3TP63_17297297_ChIP-ChIP_HaCaT_Human4.02589816
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.47284929
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.46405277
6EP300_21415370_ChIP-Seq_HL-1_Mouse2.94175453
7TBX20_22080862_ChIP-Seq_HEART_Mouse2.80340298
8TBX20_22328084_ChIP-Seq_HEART_Mouse2.80340298
9TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.78735006
10TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.69109402
11THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.56655396
12RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.31256481
13ZNF263_19887448_ChIP-Seq_K562_Human2.28210982
14RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.18032909
15NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.07780596
16* ELK3_25401928_ChIP-Seq_HUVEC_Human2.05061476
17PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.02011772
18CLOCK_20551151_ChIP-Seq_293T_Human2.00560211
19MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.98788246
20GATA2_21666600_ChIP-Seq_HMVEC_Human1.97431130
21ESR2_21235772_ChIP-Seq_MCF-7_Human1.93706965
22TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.85075305
23PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.84953431
24KDM2B_26808549_Chip-Seq_SUP-B15_Human1.78239267
25ESR1_20079471_ChIP-ChIP_T-47D_Human1.78132414
26BRD4_25478319_ChIP-Seq_HGPS_Human1.74566147
27CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.72749719
28DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.69047239
29CDX2_19796622_ChIP-Seq_MESCs_Mouse1.64275928
30ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.63553188
31EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.62899187
32CJUN_26792858_Chip-Seq_BT549_Human1.60079152
33PPAR_26484153_Chip-Seq_NCI-H1993_Human1.58459201
34* LXR_22292898_ChIP-Seq_THP-1_Human1.58295003
35RACK7_27058665_Chip-Seq_MCF-7_Human1.57531978
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.56998842
37ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.54796626
38ESR1_21235772_ChIP-Seq_MCF-7_Human1.53549618
39HIF1A_21447827_ChIP-Seq_MCF-7_Human1.52095041
40GATA4_21415370_ChIP-Seq_HL-1_Mouse1.48524416
41NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.48374139
42TET1_21451524_ChIP-Seq_MESCs_Mouse1.47016278
43ATF3_27146783_Chip-Seq_COLON_Human1.46504288
44STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.45194469
45KDM2B_26808549_Chip-Seq_DND41_Human1.44348199
46IRF8_22096565_ChIP-ChIP_GC-B_Human1.42581417
47KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.40799112
48ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.40674987
49ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.39235731
50DCP1A_22483619_ChIP-Seq_HELA_Human1.38497245
51Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.38352066
52JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.37737385
53DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.37428047
54TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37023838
55P63_26484246_Chip-Seq_KERATINOCYTES_Human1.36961806
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36355512
57* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.35563616
58* RXR_22158963_ChIP-Seq_LIVER_Mouse1.33203815
59TET1_21490601_ChIP-Seq_MESCs_Mouse1.32944706
60CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.31528525
61NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29437226
62SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.29183688
63SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.29183688
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.29065434
65P68_20966046_ChIP-Seq_HELA_Human1.28575992
66E2F1_20622854_ChIP-Seq_HELA_Human1.28513276
67UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.28214672
68JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.27819126
69SOX9_24532713_ChIP-Seq_HFSC_Mouse1.27736313
70* RAD21_21589869_ChIP-Seq_MESCs_Mouse1.27645956
71JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.26922479
72SRF_21415370_ChIP-Seq_HL-1_Mouse1.26529008
73NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.25273672
74CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.25233000
75MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.23300091
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.22968988
77* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.22943055
78CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.22335066
79* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.21922421
80SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.20663570
81NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.20651341
82SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.19254247
83RARB_24833708_ChIP-Seq_LIVER_Mouse1.18920016
84SPI1_23127762_ChIP-Seq_K562_Human1.18123889
85SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.17804610
86PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.17567347
87CTCF_27219007_Chip-Seq_ERYTHROID_Human1.16664995
88IRF8_21731497_ChIP-ChIP_J774_Mouse1.15952033
89NRF2_20460467_ChIP-Seq_MEFs_Mouse1.13715963
90NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.13715963
91GATA3_24758297_ChIP-Seq_MCF-7_Human1.13249740
92MYB_21317192_ChIP-Seq_ERMYB_Mouse1.12789333
93IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.12613748
94STAT3_1855785_ChIP-Seq_MESCs_Mouse1.11683655
95KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11587992
96SMC4_20622854_ChIP-Seq_HELA_Human1.11531945
97* RARA_24833708_ChIP-Seq_LIVER_Mouse1.10648923
98BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.10265105
99* CTCF_27219007_Chip-Seq_Bcells_Human1.09968439
100UBF1/2_26484160_Chip-Seq_HMECs_Human1.09829011
101ELF1_20517297_ChIP-Seq_JURKAT_Human1.09736180
102* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.08981522
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07508711
104P300_27058665_Chip-Seq_ZR-75-30cells_Human1.06675377
105TBX5_21415370_ChIP-Seq_HL-1_Mouse1.06019467
106GATA1_19941826_ChIP-Seq_K562_Human1.05849419
107PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.05733305
108TP53_23651856_ChIP-Seq_MEFs_Mouse1.04852318
109BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.03436720
110TCF7_22412390_ChIP-Seq_EML_Mouse1.02971930
111* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.02866926
112TP63_22573176_ChIP-Seq_HFKS_Human1.02558759
113CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.02329451
114IRF8_27001747_Chip-Seq_BMDM_Mouse1.01915941
115TP53_22127205_ChIP-Seq_IMR90_Human1.00514629
116MAF_26560356_Chip-Seq_TH1_Human1.00156259
117PHF8_20622854_ChIP-Seq_HELA_Human0.99978812
118LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.98880764
119GATA2_19941826_ChIP-Seq_K562_Human0.98452990
120RUNX1_27514584_Chip-Seq_MCF-7_Human0.98147858
121BCL6_27268052_Chip-Seq_Bcells_Human0.97653850
122SOX2_20726797_ChIP-Seq_SW620_Human0.97064736
123SMAD_19615063_ChIP-ChIP_OVARY_Human0.96815572
124CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.96779404
125VDR_21846776_ChIP-Seq_THP-1_Human0.96644220
126SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96514932
127NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95918462
128CSB_26484114_Chip-Seq_FIBROBLAST_Human0.94826374
129SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.94649821
130RXRA_24833708_ChIP-Seq_LIVER_Mouse0.94483473
131SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.94082710
132CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.93862756
133KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.93279818
134P53_21459846_ChIP-Seq_SAOS-2_Human0.93244713
135SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92766485
136BCOR_27268052_Chip-Seq_Bcells_Human0.92575332
137STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90954333
138ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.90745084
139FOXO3_23340844_ChIP-Seq_DLD1_Human0.90578677

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.52476420
2MP0000751_myopathy4.81693310
3MP0003646_muscle_fatigue4.51705541
4MP0004084_abnormal_cardiac_muscle4.43793641
5MP0000749_muscle_degeneration3.88615374
6MP0008438_abnormal_cutaneous_collagen3.52269809
7MP0004215_abnormal_myocardial_fiber3.48776630
8MP0004036_abnormal_muscle_relaxation3.24235808
9MP0005330_cardiomyopathy3.21867478
10MP0005451_abnormal_body_composition3.12299391
11MP0000750_abnormal_muscle_regeneration3.04796903
12MP0004087_abnormal_muscle_fiber2.76591199
13MP0003279_aneurysm2.51156350
14MP0002972_abnormal_cardiac_muscle2.47842234
15MP0008775_abnormal_heart_ventricle2.45275553
16MP0003705_abnormal_hypodermis_morpholog2.41555171
17MP0002106_abnormal_muscle_physiology2.31670028
18MP0005275_abnormal_skin_tensile2.29681305
19MP0003828_pulmonary_edema2.28077071
20MP0001544_abnormal_cardiovascular_syste2.22375711
21MP0005385_cardiovascular_system_phenoty2.22375711
22MP0010630_abnormal_cardiac_muscle2.22317833
23MP0004510_myositis2.21281736
24MP0005620_abnormal_muscle_contractility2.19901055
25MP0004130_abnormal_muscle_cell2.03473694
26MP0002269_muscular_atrophy2.03329491
27MP0005171_absent_coat_pigmentation2.01866678
28MP0003137_abnormal_impulse_conducting1.99325014
29MP0000759_abnormal_skeletal_muscle1.95718467
30MP0004484_altered_response_of1.93482390
31MP0005369_muscle_phenotype1.93192285
32MP0006138_congestive_heart_failure1.90617814
33MP0000747_muscle_weakness1.76908179
34MP0001958_emphysema1.76293220
35MP0009780_abnormal_chondrocyte_physiolo1.74659114
36MP0010368_abnormal_lymphatic_system1.65701751
37MP0004145_abnormal_muscle_electrophysio1.64679519
38MP0003566_abnormal_cell_adhesion1.61744960
39MP0000343_altered_response_to1.61566099
40MP0003950_abnormal_plasma_membrane1.59854411
41MP0004233_abnormal_muscle_weight1.52245790
42MP0005360_urolithiasis1.51817108
43MP0005503_abnormal_tendon_morphology1.51290475
44MP0003136_yellow_coat_color1.48510736
45MP0005623_abnormal_meninges_morphology1.37052715
46MP0004085_abnormal_heartbeat1.36807186
47MP0005670_abnormal_white_adipose1.36773305
48MP0003221_abnormal_cardiomyocyte_apopto1.34327309
49MP0002332_abnormal_exercise_endurance1.33647352
50MP0005666_abnormal_adipose_tissue1.32356362
51MP0000767_abnormal_smooth_muscle1.30376066
52MP0004272_abnormal_basement_membrane1.25381324
53MP0010030_abnormal_orbit_morphology1.20607544
54MP0005083_abnormal_biliary_tract1.19141691
55MP0000733_abnormal_muscle_development1.17829906
56MP0000678_abnormal_parathyroid_gland1.17813757
57MP0001879_abnormal_lymphatic_vessel1.17125481
58MP0002108_abnormal_muscle_morphology1.11913784
59MP0002127_abnormal_cardiovascular_syste1.11083699
60MP0001661_extended_life_span1.10175789
61MP0004185_abnormal_adipocyte_glucose1.09412278
62MP0005165_increased_susceptibility_to1.07935190
63MP0001299_abnormal_eye_distance/1.00755250
64MP0002128_abnormal_blood_circulation1.00041518
65MP0000266_abnormal_heart_morphology0.99929282
66MP0005375_adipose_tissue_phenotype0.98659752
67MP0003567_abnormal_fetal_cardiomyocyte0.97807629
68MP0009840_abnormal_foam_cell0.93886344
69MP0005023_abnormal_wound_healing0.92746392
70MP0000467_abnormal_esophagus_morphology0.91758464
71MP0006036_abnormal_mitochondrial_physio0.90392988
72MP0002877_abnormal_melanocyte_morpholog0.89603749
73MP0005058_abnormal_lysosome_morphology0.89222057
74MP0001348_abnormal_lacrimal_gland0.88905003
75MP0000762_abnormal_tongue_morphology0.88676175
76MP0003091_abnormal_cell_migration0.84543375
77MP0009250_abnormal_appendicular_skeleto0.84085414
78MP0003045_fibrosis0.83577445
79MP0003942_abnormal_urinary_system0.82538576
80MP0002060_abnormal_skin_morphology0.81666089
81MP0000534_abnormal_ureter_morphology0.80036502
82MP0000538_abnormal_urinary_bladder0.78831228
83MP0002896_abnormal_bone_mineralization0.78547868
84MP0002234_abnormal_pharynx_morphology0.78047289
85MP0006054_spinal_hemorrhage0.77999651
86MP0009384_cardiac_valve_regurgitation0.77686554
87MP0001664_abnormal_digestion0.75459245
88MP0000372_irregular_coat_pigmentation0.72101465
89MP0004134_abnormal_chest_morphology0.70862009
90MP0002295_abnormal_pulmonary_circulatio0.67582374
91MP0000230_abnormal_systemic_arterial0.64798953
92MP0001614_abnormal_blood_vessel0.64753617
93MP0002998_abnormal_bone_remodeling0.63596012
94MP0008875_abnormal_xenobiotic_pharmacok0.62995327
95MP0000427_abnormal_hair_cycle0.62565591
96MP0005501_abnormal_skin_physiology0.61447449
97MP0002249_abnormal_larynx_morphology0.61370022
98MP0000163_abnormal_cartilage_morphology0.60184592
99MP0005409_darkened_coat_color0.60075295
100MP0000013_abnormal_adipose_tissue0.60007656
101MP0003303_peritoneal_inflammation0.58817394
102MP0010771_integument_phenotype0.58775497
103MP0000003_abnormal_adipose_tissue0.57920289
104MP0002160_abnormal_reproductive_system0.57609515
105MP0004147_increased_porphyrin_level0.57453542
106MP0001533_abnormal_skeleton_physiology0.56889985
107MP0003385_abnormal_body_wall0.56811249
108MP0005332_abnormal_amino_acid0.56557289
109MP0001986_abnormal_taste_sensitivity0.56409049
110MP0000249_abnormal_blood_vessel0.56017553
111MP0005257_abnormal_intraocular_pressure0.55999402
112MP0005508_abnormal_skeleton_morphology0.55847905
113MP0002925_abnormal_cardiovascular_devel0.55842145
114MP0009278_abnormal_bone_marrow0.55479477
115MP0005595_abnormal_vascular_smooth0.55182317
116MP0002971_abnormal_brown_adipose0.52908243
117MP0002933_joint_inflammation0.51750518
118MP0003436_decreased_susceptibility_to0.51158839
119MP0003724_increased_susceptibility_to0.51041234
120MP0001243_abnormal_dermal_layer0.50489831
121MP0003941_abnormal_skin_development0.49355608
122MP0003448_altered_tumor_morphology0.47486224
123MP0005266_abnormal_metabolism0.47119972
124MP0005390_skeleton_phenotype0.46933464
125MP0009115_abnormal_fat_cell0.44714625
126MP0002148_abnormal_hypersensitivity_rea0.44438942
127MP0006035_abnormal_mitochondrial_morpho0.43929404
128MP0001853_heart_inflammation0.43801969
129MP0001542_abnormal_bone_strength0.43611209
130MP0002089_abnormal_postnatal_growth/wei0.43010002
131MP0002133_abnormal_respiratory_system0.42484354
132MP0005388_respiratory_system_phenotype0.42484354
133MP0005319_abnormal_enzyme/_coenzyme0.40874332

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.62186941
2Muscle fiber splitting (HP:0003555)5.92120867
3Ventricular tachycardia (HP:0004756)5.88096493
4Increased connective tissue (HP:0009025)5.35730777
5Calf muscle hypertrophy (HP:0008981)5.28503371
6Right ventricular cardiomyopathy (HP:0011663)5.07147243
7Atrial fibrillation (HP:0005110)5.00606345
8Hyporeflexia of lower limbs (HP:0002600)4.92010325
9Abnormality of the calf musculature (HP:0001430)4.89567223
10Lipoatrophy (HP:0100578)4.79591544
11Muscle hypertrophy of the lower extremities (HP:0008968)4.79586703
12Exercise-induced muscle cramps (HP:0003710)4.78543053
13Primary atrial arrhythmia (HP:0001692)4.66009920
14Exercise-induced myalgia (HP:0003738)4.55559601
15Supraventricular tachycardia (HP:0004755)4.48590866
16Supraventricular arrhythmia (HP:0005115)4.43084912
17Asymmetric septal hypertrophy (HP:0001670)4.24667417
18EMG: myopathic abnormalities (HP:0003458)4.14781846
19Subaortic stenosis (HP:0001682)4.11446047
20Abnormality of the left ventricular outflow tract (HP:0011103)4.11446047
21Type 1 muscle fiber predominance (HP:0003803)4.08251832
22Dilated cardiomyopathy (HP:0001644)3.84995339
23Difficulty climbing stairs (HP:0003551)3.65879014
24Premature rupture of membranes (HP:0001788)3.65250057
25Protrusio acetabuli (HP:0003179)3.64331201
26Syncope (HP:0001279)3.63762277
27Bundle branch block (HP:0011710)3.62143869
28Difficulty running (HP:0009046)3.46696179
29Prolonged QT interval (HP:0001657)3.42682433
30Myoglobinuria (HP:0002913)3.40023622
31Increased variability in muscle fiber diameter (HP:0003557)3.31869070
32Palpitations (HP:0001962)3.25795681
33Abnormality of skeletal muscle fiber size (HP:0012084)3.20491136
34Abnormal atrioventricular conduction (HP:0005150)3.19789682
35Ventricular arrhythmia (HP:0004308)3.18492734
36Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.14267138
37Muscle fiber inclusion bodies (HP:0100299)3.12420525
38Ulnar deviation of the wrist (HP:0003049)3.11845907
39Heart block (HP:0012722)3.10411721
40Mildly elevated creatine phosphokinase (HP:0008180)3.10283118
41Atrioventricular block (HP:0001678)3.09042657
42Myotonia (HP:0002486)3.07085891
43Distal lower limb muscle weakness (HP:0009053)3.05899799
44Broad metatarsal (HP:0001783)3.02921131
45Slender build (HP:0001533)2.97776518
46Distal lower limb amyotrophy (HP:0008944)2.96288693
47Follicular hyperkeratosis (HP:0007502)2.90060943
48Testicular atrophy (HP:0000029)2.73360921
49Rhabdomyolysis (HP:0003201)2.65719124
50Spinal rigidity (HP:0003306)2.65575301
51Limb-girdle muscle atrophy (HP:0003797)2.59890257
52Elbow flexion contracture (HP:0002987)2.59223827
53Cerebral aneurysm (HP:0004944)2.58242812
54Ankle contracture (HP:0006466)2.54984684
55Ventricular fibrillation (HP:0001663)2.46457983
56Round ear (HP:0100830)2.45020378
57Neck muscle weakness (HP:0000467)2.43407534
58Vascular tortuosity (HP:0004948)2.41447274
59Nemaline bodies (HP:0003798)2.37038373
60Abnormal EKG (HP:0003115)2.34132728
61Scapular winging (HP:0003691)2.33648174
62Muscular dystrophy (HP:0003560)2.29072806
63Fragile skin (HP:0001030)2.28929888
64Facial diplegia (HP:0001349)2.26937187
65Wrist flexion contracture (HP:0001239)2.26227773
66Entropion (HP:0000621)2.23849073
67Areflexia of lower limbs (HP:0002522)2.23747026
68Palmoplantar keratoderma (HP:0000982)2.23125408
69Lower limb amyotrophy (HP:0007210)2.22638123
70Aortic dissection (HP:0002647)2.21836960
71Distal upper limb amyotrophy (HP:0007149)2.19456911
72Upper limb amyotrophy (HP:0009129)2.19456911
73Delayed gross motor development (HP:0002194)2.14369916
74Breech presentation (HP:0001623)2.12985602
75Atrophic scars (HP:0001075)2.10070664
76Muscle stiffness (HP:0003552)2.09718639
77Aortic aneurysm (HP:0004942)2.08248117
78Mesangial abnormality (HP:0001966)2.08160257
79Wormian bones (HP:0002645)2.07501142
80Gowers sign (HP:0003391)2.03618336
81Aneurysm (HP:0002617)2.03604924
82Generalized muscle weakness (HP:0003324)2.03096476
83Myopathic facies (HP:0002058)2.02979892
84Pulmonary artery stenosis (HP:0004415)2.01752321
85Congestive heart failure (HP:0001635)1.98174923
86Deformed tarsal bones (HP:0008119)1.97197981
87Nonimmune hydrops fetalis (HP:0001790)1.96554718
88Vertebral compression fractures (HP:0002953)1.96420120
89Generalized amyotrophy (HP:0003700)1.95341200
90Shallow orbits (HP:0000586)1.95124116
91Hip contracture (HP:0003273)1.94729291
92Bradycardia (HP:0001662)1.94197487
93Axonal loss (HP:0003447)1.93750504
94Left ventricular hypertrophy (HP:0001712)1.93327949
95Distal arthrogryposis (HP:0005684)1.93043334
96Aortic regurgitation (HP:0001659)1.92953521
97Foot dorsiflexor weakness (HP:0009027)1.92175578
98Sudden cardiac death (HP:0001645)1.92000921
99Infantile muscular hypotonia (HP:0008947)1.91544674
100Polycythemia (HP:0001901)1.91047495
101Ulnar bowing (HP:0003031)1.91014536
102Abnormality of the foot musculature (HP:0001436)1.90522056
103Neoplasm of head and neck (HP:0012288)1.89563730
104Esophageal neoplasm (HP:0100751)1.89563730
105Mitral stenosis (HP:0001718)1.88576539
106Frequent falls (HP:0002359)1.87938028
107Arterial tortuosity (HP:0005116)1.87195889
108Abnormality of dentin (HP:0010299)1.87053888
109Abnormality of the umbilical cord (HP:0010881)1.83792020
110Hypoplastic ischia (HP:0003175)1.83694823
111Soft skin (HP:0000977)1.81402472
112Type II lissencephaly (HP:0007260)1.79491555
113Progressive muscle weakness (HP:0003323)1.77705128
114Cervical subluxation (HP:0003308)1.77452146
115Abnormal delivery (HP:0001787)1.77300462
116Achilles tendon contracture (HP:0001771)1.77025774
117Calcaneovalgus deformity (HP:0001848)1.76933520
118Popliteal pterygium (HP:0009756)1.76882037
119Redundant skin (HP:0001582)1.75973238
120Cardiovascular calcification (HP:0011915)1.74988084
121Stridor (HP:0010307)1.74434490
122Reduced subcutaneous adipose tissue (HP:0003758)1.72630096
123Peritonitis (HP:0002586)1.72467272
124Abnormality of the neuromuscular junction (HP:0003398)1.72450937
125Fatigable weakness (HP:0003473)1.72450937
126Difficulty walking (HP:0002355)1.71649953
127Joint stiffness (HP:0001387)1.71230134
128Malignant hyperthermia (HP:0002047)1.70566620
129EMG: neuropathic changes (HP:0003445)1.69356032
130Tongue fasciculations (HP:0001308)1.68908910
131Centrally nucleated skeletal muscle fibers (HP:0003687)1.67700048
132Bladder diverticulum (HP:0000015)1.62685398
133Limb-girdle muscle weakness (HP:0003325)1.61895233
134Bulbar palsy (HP:0001283)1.60680468
135Hepatic necrosis (HP:0002605)1.59641180

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN6.50071253
2OBSCN3.68541165
3TRIB33.41650196
4MYLK3.10423782
5DMPK3.06219205
6LMTK22.96063490
7PKN22.84279850
8EPHA22.80204440
9PHKG12.74484468
10PHKG22.74484468
11MUSK2.54736139
12ERN12.22135721
13TIE12.20061929
14TGFBR22.14444585
15PRKD22.05077130
16LIMK12.00913918
17PDK41.99082127
18PDK31.99082127
19PIK3CA1.89776369
20ADRBK21.65926491
21NME21.63987142
22RIPK11.57488161
23TRPM71.51662239
24PDGFRA1.49698618
25PDK21.46713976
26BCKDK1.38051955
27TESK11.35856038
28MAP2K31.35720543
29MAPKAPK31.31021696
30PRKD11.18599446
31PINK11.14406969
32ADRBK11.12323415
33DDR21.07517463
34BUB11.07484354
35PIK3CG1.07228024
36ILK1.06983166
37PAK31.05544666
38CCNB11.02263786
39PIM21.02174486
40ROCK11.02105453
41ZAK1.01917821
42TBK11.01807511
43MAP3K30.98619201
44TGFBR10.98446890
45WNK40.98443592
46STK38L0.94439980
47EPHB10.94089609
48EPHB20.92753235
49DAPK30.91647233
50MAPK110.91567930
51MAPK120.91029848
52NEK90.90804957
53NEK10.90408462
54BMX0.89366420
55STK240.89250513
56PRKD30.88364602
57STK40.87281782
58MAP3K120.84038774
59BLK0.83997881
60CAMK2D0.83819300
61MAP3K50.83752550
62MAP3K70.83443308
63MST1R0.79223693
64PTK60.78779230
65ARAF0.77486424
66SIK10.76908305
67PRKCI0.75445731
68MAP2K60.74935040
69FLT30.74585568
70CAMK2G0.74454735
71GRK50.74035232
72KDR0.72157137
73FER0.70632250
74EIF2AK10.70436482
75PRKCE0.70280794
76LRRK20.70015084
77PRKG20.69921926
78ERBB40.69825381
79PTK2B0.69453163
80CDC42BPA0.67376084
81GRK70.66159435
82RPS6KC10.65805602
83RPS6KL10.65805602
84IRAK30.65368102
85LATS20.62878240
86RPS6KA60.61852479
87RPS6KA40.60430210
88JAK10.58475115
89KIT0.58180497
90PRKAA20.57797581
91CAMK1D0.55072002
92PBK0.54482282
93TAOK10.54253482
94ROCK20.52944819
95TYK20.51840846
96BRSK20.51741904
97NME10.51546631
98PAK20.51277142
99MAP3K110.50048064
100ABL20.49498697
101AKT30.49120692
102MAPK70.48600646
103PRKAA10.48348923
104STK380.47651414
105GRK10.47588036
106CAMK40.45177662
107STK30.44140387
108JAK30.43813837
109MTOR0.43694375
110MELK0.42683340
111WEE10.42288724
112AKT20.41127946
113PKN10.40624463
114MAP3K100.40384978
115LATS10.40185233
116EEF2K0.39850004
117BRSK10.39815507
118EPHA30.39017261
119PDGFRB0.38481013
120MOS0.37409862
121PAK10.37054145
122ZAP700.36064281
123MAP3K60.35707269
124FGFR40.34914373
125GRK60.34354994
126MET0.34167165
127NTRK10.33761509
128TAOK20.33349511
129PDPK10.32527028
130PAK40.30841162
131WNK10.30823381
132MAPKAPK20.30495708
133PTK20.30246416
134MAP2K10.30178212
135HCK0.30010597
136INSRR0.29299582
137ICK0.28561207
138RPS6KA20.28504233

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.41197998
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.35890094
3Dilated cardiomyopathy_Homo sapiens_hsa054144.28380864
4Cardiac muscle contraction_Homo sapiens_hsa042603.43268471
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.14906591
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.06711030
7Viral myocarditis_Homo sapiens_hsa054162.55694213
8Sulfur relay system_Homo sapiens_hsa041222.35520274
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.24610884
10Fatty acid degradation_Homo sapiens_hsa000712.01841369
11Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.98006438
12Cyanoamino acid metabolism_Homo sapiens_hsa004601.93168324
13ECM-receptor interaction_Homo sapiens_hsa045121.86874703
14Parkinsons disease_Homo sapiens_hsa050121.78164920
15Focal adhesion_Homo sapiens_hsa045101.74946460
16Carbon metabolism_Homo sapiens_hsa012001.70114415
17Oxidative phosphorylation_Homo sapiens_hsa001901.67366798
18Propanoate metabolism_Homo sapiens_hsa006401.66317422
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.59646092
20Pentose phosphate pathway_Homo sapiens_hsa000301.56999813
21N-Glycan biosynthesis_Homo sapiens_hsa005101.52830957
22Amoebiasis_Homo sapiens_hsa051461.47020024
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43874397
24Arginine biosynthesis_Homo sapiens_hsa002201.43853789
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.40363530
26Alzheimers disease_Homo sapiens_hsa050101.40123743
27Adipocytokine signaling pathway_Homo sapiens_hsa049201.35439214
28Fatty acid metabolism_Homo sapiens_hsa012121.34108434
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.32637389
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.29944056
31Insulin resistance_Homo sapiens_hsa049311.28386287
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.27145340
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.26378181
34Starch and sucrose metabolism_Homo sapiens_hsa005001.23035031
35Sphingolipid metabolism_Homo sapiens_hsa006001.15802878
36Galactose metabolism_Homo sapiens_hsa000521.14009106
37HIF-1 signaling pathway_Homo sapiens_hsa040661.13601882
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.13278743
39Proteoglycans in cancer_Homo sapiens_hsa052051.12474048
40Sulfur metabolism_Homo sapiens_hsa009201.09540465
41Malaria_Homo sapiens_hsa051441.06109507
42Leishmaniasis_Homo sapiens_hsa051401.04155323
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03399732
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.99794833
45PPAR signaling pathway_Homo sapiens_hsa033200.99344077
46Circadian rhythm_Homo sapiens_hsa047100.98428832
47Salmonella infection_Homo sapiens_hsa051320.98188460
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97571605
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97507754
50Glutathione metabolism_Homo sapiens_hsa004800.96161492
51Adherens junction_Homo sapiens_hsa045200.95018738
52Toxoplasmosis_Homo sapiens_hsa051450.93282644
53Caffeine metabolism_Homo sapiens_hsa002320.92970696
54Leukocyte transendothelial migration_Homo sapiens_hsa046700.92663851
55Insulin signaling pathway_Homo sapiens_hsa049100.89430458
56Huntingtons disease_Homo sapiens_hsa050160.88552179
57Selenocompound metabolism_Homo sapiens_hsa004500.84529976
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83335579
59Glycosaminoglycan degradation_Homo sapiens_hsa005310.82965058
60Osteoclast differentiation_Homo sapiens_hsa043800.82790444
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82584898
62Other glycan degradation_Homo sapiens_hsa005110.81686505
63Hedgehog signaling pathway_Homo sapiens_hsa043400.81608387
64Regulation of actin cytoskeleton_Homo sapiens_hsa048100.80928133
65Platelet activation_Homo sapiens_hsa046110.80511131
66Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.80367860
67Small cell lung cancer_Homo sapiens_hsa052220.79282236
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76591892
69ABC transporters_Homo sapiens_hsa020100.75370426
70Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.75221183
71One carbon pool by folate_Homo sapiens_hsa006700.75109404
72Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73170997
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72375830
74cGMP-PKG signaling pathway_Homo sapiens_hsa040220.72292081
75Lysosome_Homo sapiens_hsa041420.71165175
76Folate biosynthesis_Homo sapiens_hsa007900.70746533
77Pertussis_Homo sapiens_hsa051330.69158736
78Toll-like receptor signaling pathway_Homo sapiens_hsa046200.68933506
79Tuberculosis_Homo sapiens_hsa051520.66433378
80AMPK signaling pathway_Homo sapiens_hsa041520.66041867
81Pyruvate metabolism_Homo sapiens_hsa006200.65243704
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64747630
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.64723571
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.63749407
85TGF-beta signaling pathway_Homo sapiens_hsa043500.63411674
86Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62518132
87Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.62502073
88Butanoate metabolism_Homo sapiens_hsa006500.62409342
89Protein digestion and absorption_Homo sapiens_hsa049740.62221009
90Legionellosis_Homo sapiens_hsa051340.61025201
91Tight junction_Homo sapiens_hsa045300.60758062
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59871208
93Lysine degradation_Homo sapiens_hsa003100.59122070
94Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.58680434
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58471907
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58453303
97TNF signaling pathway_Homo sapiens_hsa046680.57848722
98Hippo signaling pathway_Homo sapiens_hsa043900.57629353
99Apoptosis_Homo sapiens_hsa042100.57115573
100Phagosome_Homo sapiens_hsa041450.56775801
101Metabolic pathways_Homo sapiens_hsa011000.55831460
102Glucagon signaling pathway_Homo sapiens_hsa049220.55238451
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54756782
104Staphylococcus aureus infection_Homo sapiens_hsa051500.54069523
105Type II diabetes mellitus_Homo sapiens_hsa049300.53732084
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52898063
107Basal transcription factors_Homo sapiens_hsa030220.50640293
108Chronic myeloid leukemia_Homo sapiens_hsa052200.50377953
109Nucleotide excision repair_Homo sapiens_hsa034200.49962702
110Acute myeloid leukemia_Homo sapiens_hsa052210.49668240
111PI3K-Akt signaling pathway_Homo sapiens_hsa041510.48504050
112Melanogenesis_Homo sapiens_hsa049160.47254570
113Cysteine and methionine metabolism_Homo sapiens_hsa002700.46226411
114Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45923770
115Fructose and mannose metabolism_Homo sapiens_hsa000510.45778490
116Biosynthesis of amino acids_Homo sapiens_hsa012300.45117171
117Oxytocin signaling pathway_Homo sapiens_hsa049210.44574033
118Bladder cancer_Homo sapiens_hsa052190.44048270
119VEGF signaling pathway_Homo sapiens_hsa043700.43842394
120Basal cell carcinoma_Homo sapiens_hsa052170.43264229
121Calcium signaling pathway_Homo sapiens_hsa040200.43167616
122Inositol phosphate metabolism_Homo sapiens_hsa005620.42732853
123Arginine and proline metabolism_Homo sapiens_hsa003300.42480220
124Nitrogen metabolism_Homo sapiens_hsa009100.42414130
125Rheumatoid arthritis_Homo sapiens_hsa053230.41153163
126Jak-STAT signaling pathway_Homo sapiens_hsa046300.38963041
127Mineral absorption_Homo sapiens_hsa049780.38925746
128Notch signaling pathway_Homo sapiens_hsa043300.38484454
129Fat digestion and absorption_Homo sapiens_hsa049750.38289903
130Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37314933
131Fatty acid elongation_Homo sapiens_hsa000620.35846994
132Melanoma_Homo sapiens_hsa052180.35486612
133Vibrio cholerae infection_Homo sapiens_hsa051100.35273049
134Ovarian steroidogenesis_Homo sapiens_hsa049130.35249877
135Shigellosis_Homo sapiens_hsa051310.34706726
136Renal cell carcinoma_Homo sapiens_hsa052110.34008292
137Primary bile acid biosynthesis_Homo sapiens_hsa001200.33212586
138Pyrimidine metabolism_Homo sapiens_hsa002400.33021598
139RNA polymerase_Homo sapiens_hsa030200.32939979
140Rap1 signaling pathway_Homo sapiens_hsa040150.30614172
141Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.30024867
142NF-kappa B signaling pathway_Homo sapiens_hsa040640.28106466
143Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.27597419
144GnRH signaling pathway_Homo sapiens_hsa049120.25736769
145Hematopoietic cell lineage_Homo sapiens_hsa046400.24773655
146Pathways in cancer_Homo sapiens_hsa052000.24677593
147Influenza A_Homo sapiens_hsa051640.24568314
148FoxO signaling pathway_Homo sapiens_hsa040680.24184854

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