ADCK1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tricarboxylic acid cycle (GO:0006099)5.72071002
2NADH metabolic process (GO:0006734)5.57923230
3regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)5.27302805
4respiratory chain complex IV assembly (GO:0008535)5.10621816
5cytochrome complex assembly (GO:0017004)4.90200172
6protein complex biogenesis (GO:0070271)4.84989337
7succinate metabolic process (GO:0006105)4.62796086
8mitochondrial respiratory chain complex assembly (GO:0033108)4.60349982
9oxaloacetate metabolic process (GO:0006107)4.49296161
10oxidative phosphorylation (GO:0006119)4.47849208
11regulation of mitochondrial translation (GO:0070129)4.24864519
12chaperone-mediated protein transport (GO:0072321)4.17437329
13water-soluble vitamin biosynthetic process (GO:0042364)4.14516112
14mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.13793701
15behavioral response to nicotine (GO:0035095)4.09647349
16neurotransmitter-gated ion channel clustering (GO:0072578)4.07626770
17RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.07294565
18tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.07294565
19regulation of acyl-CoA biosynthetic process (GO:0050812)4.06791409
20regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.05093011
21piRNA metabolic process (GO:0034587)3.97398602
22establishment of protein localization to mitochondrial membrane (GO:0090151)3.94048202
23adenine nucleotide transport (GO:0051503)3.91648050
242-oxoglutarate metabolic process (GO:0006103)3.91519260
25mitochondrial RNA metabolic process (GO:0000959)3.87413728
26purine ribonucleotide transport (GO:0015868)3.86686043
27base-excision repair, AP site formation (GO:0006285)3.84365575
28regulation of short-term neuronal synaptic plasticity (GO:0048172)3.82366081
29regulation of female receptivity (GO:0045924)3.81260994
30regulation of cofactor metabolic process (GO:0051193)3.80646494
31regulation of coenzyme metabolic process (GO:0051196)3.80646494
32axoneme assembly (GO:0035082)3.78079851
33DNA methylation involved in gamete generation (GO:0043046)3.75006057
34regulation of cellular respiration (GO:0043457)3.74197073
35purine nucleotide transport (GO:0015865)3.70857567
36aspartate family amino acid catabolic process (GO:0009068)3.68916866
37mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.68299549
38female mating behavior (GO:0060180)3.67174805
39protein deneddylation (GO:0000338)3.67145244
40regulation of oxidative phosphorylation (GO:0002082)3.66204218
41cullin deneddylation (GO:0010388)3.65938032
42metallo-sulfur cluster assembly (GO:0031163)3.63172509
43iron-sulfur cluster assembly (GO:0016226)3.63172509
44intracellular protein transmembrane import (GO:0044743)3.57914376
45respiratory electron transport chain (GO:0022904)3.56532001
46carnitine metabolic process (GO:0009437)3.52343704
47electron transport chain (GO:0022900)3.49108739
48neuron cell-cell adhesion (GO:0007158)3.48839606
49cell communication by electrical coupling (GO:0010644)3.48067924
50synaptic vesicle exocytosis (GO:0016079)3.45371499
51regulation of cilium movement (GO:0003352)3.42155939
52lysine catabolic process (GO:0006554)3.32547050
53lysine metabolic process (GO:0006553)3.32547050
54ubiquinone biosynthetic process (GO:0006744)3.32153644
55quinone biosynthetic process (GO:1901663)3.32153644
56regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.31880551
57platelet dense granule organization (GO:0060155)3.27250128
58L-fucose catabolic process (GO:0042355)3.23605222
59fucose catabolic process (GO:0019317)3.23605222
60L-fucose metabolic process (GO:0042354)3.23605222
61G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.23321737
62ATP biosynthetic process (GO:0006754)3.21152896
63regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.20661051
64pseudouridine synthesis (GO:0001522)3.20507877
65regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.20278247
66protein polyglutamylation (GO:0018095)3.20050353
67dicarboxylic acid catabolic process (GO:0043649)3.19747119
68vocalization behavior (GO:0071625)3.18320359
69glutathione biosynthetic process (GO:0006750)3.16765486
70synaptic vesicle docking involved in exocytosis (GO:0016081)3.15439930
71glutamate secretion (GO:0014047)3.15280015
72ATP synthesis coupled proton transport (GO:0015986)3.14826249
73energy coupled proton transport, down electrochemical gradient (GO:0015985)3.14826249
74brain morphogenesis (GO:0048854)3.13141888
75purine nucleoside triphosphate biosynthetic process (GO:0009145)3.12939132
76pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.09106999
77nonmotile primary cilium assembly (GO:0035058)3.08805838
78fatty acid homeostasis (GO:0055089)3.08362083
79postsynaptic membrane organization (GO:0001941)3.07633256
80regulation of synaptic vesicle exocytosis (GO:2000300)3.04722631
81positive regulation of protein homodimerization activity (GO:0090073)3.04488364
82amino-acid betaine metabolic process (GO:0006577)3.03928241
83anterograde synaptic vesicle transport (GO:0048490)3.03675759
84amino acid salvage (GO:0043102)3.03036393
85L-methionine salvage (GO:0071267)3.03036393
86L-methionine biosynthetic process (GO:0071265)3.03036393
87regulation of sulfur metabolic process (GO:0042762)3.02698359
88nonribosomal peptide biosynthetic process (GO:0019184)3.02437200
89preassembly of GPI anchor in ER membrane (GO:0016254)3.02252903
90purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.01426789
91positive regulation of neurotransmitter transport (GO:0051590)2.98388101
92transcription from mitochondrial promoter (GO:0006390)2.97993018
93pyrimidine nucleotide catabolic process (GO:0006244)2.97540550
94positive regulation of neurotransmitter secretion (GO:0001956)2.97172458
95gamma-aminobutyric acid transport (GO:0015812)2.97159481
96tRNA processing (GO:0008033)2.95244883
97aerobic respiration (GO:0009060)2.94903637
98negative regulation of synaptic transmission, GABAergic (GO:0032229)2.94137118
99regulation of glutamate receptor signaling pathway (GO:1900449)2.93626262
100neurotransmitter secretion (GO:0007269)2.93253846
101ubiquinone metabolic process (GO:0006743)2.93246463
102establishment of protein localization to mitochondrion (GO:0072655)2.89533763
103acetyl-CoA metabolic process (GO:0006084)2.89413846
104negative regulation of mast cell activation (GO:0033004)2.87258090
105glycerophospholipid catabolic process (GO:0046475)2.87196712
106ATP hydrolysis coupled proton transport (GO:0015991)2.86333275
107energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.86333275
108protein targeting to mitochondrion (GO:0006626)2.86109394
109tRNA modification (GO:0006400)2.85367599
110regulation of synaptic vesicle transport (GO:1902803)2.84210948
111behavioral response to ethanol (GO:0048149)2.83473326
112tRNA metabolic process (GO:0006399)2.83320308
113ethanol oxidation (GO:0006069)2.83177427
114proteasome assembly (GO:0043248)2.82859826
115protein import into peroxisome matrix (GO:0016558)2.81868523
116NAD metabolic process (GO:0019674)2.81835924
117endothelium development (GO:0003158)2.81395740
118protein localization to synapse (GO:0035418)2.81193737
119fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.81121034
120gluconeogenesis (GO:0006094)2.79816771
121cellular ketone body metabolic process (GO:0046950)2.78673021
122neuromuscular process controlling posture (GO:0050884)2.77758667
123mannosylation (GO:0097502)2.77393725
124inositol phosphate catabolic process (GO:0071545)2.75878500
125peptidyl-histidine modification (GO:0018202)2.75793529
126positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.75098705
127intracellular protein transmembrane transport (GO:0065002)2.75001481
128cysteine metabolic process (GO:0006534)2.75001398
129membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.73736507
130regulation of synapse structural plasticity (GO:0051823)2.73592336
131DNA double-strand break processing (GO:0000729)2.72482974
132inositol phosphate dephosphorylation (GO:0046855)2.71893261
133phosphorylated carbohydrate dephosphorylation (GO:0046838)2.71893261
134alpha-linolenic acid metabolic process (GO:0036109)2.71395618
135protein localization to mitochondrion (GO:0070585)2.70034528
136aldehyde catabolic process (GO:0046185)2.69993895
137regulation of nuclear cell cycle DNA replication (GO:0033262)2.69237583
138hydrogen ion transmembrane transport (GO:1902600)2.68779592
139mitochondrial respiratory chain complex I assembly (GO:0032981)2.67762176
140NADH dehydrogenase complex assembly (GO:0010257)2.67762176
141mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.67762176
142short-chain fatty acid metabolic process (GO:0046459)2.67607747
143coenzyme catabolic process (GO:0009109)2.66560157
144protein-cofactor linkage (GO:0018065)2.66514433
145GMP metabolic process (GO:0046037)2.65595592
146DNA damage response, detection of DNA damage (GO:0042769)2.64645828
147positive regulation of mitochondrial fission (GO:0090141)2.64344545
148regulation of cell communication by electrical coupling (GO:0010649)2.64318278
149hexose biosynthetic process (GO:0019319)2.63108499
150epithelial cilium movement (GO:0003351)2.62071244
151fat-soluble vitamin biosynthetic process (GO:0042362)2.61432398
152thioester biosynthetic process (GO:0035384)2.60898366
153acyl-CoA biosynthetic process (GO:0071616)2.60898366
154proton transport (GO:0015992)2.60277858
155male meiosis I (GO:0007141)2.60091943
156ribonucleoside triphosphate biosynthetic process (GO:0009201)2.58542219
157protein neddylation (GO:0045116)2.57280165
158locomotory exploration behavior (GO:0035641)2.57025162
159hydrogen transport (GO:0006818)2.56785310
160glyoxylate metabolic process (GO:0046487)2.54843015
161regulation of microtubule-based movement (GO:0060632)2.54803828
162presynaptic membrane assembly (GO:0097105)2.53893276
163regulation of action potential (GO:0098900)2.53358613
164pyrimidine nucleobase catabolic process (GO:0006208)2.53163949
165proline transport (GO:0015824)2.52558344
166dicarboxylic acid biosynthetic process (GO:0043650)2.52487823
167activation of protein kinase A activity (GO:0034199)2.50928741
168L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.49543199
169S-adenosylmethionine metabolic process (GO:0046500)2.49250596
170branched-chain amino acid catabolic process (GO:0009083)2.48189538
171ketone body metabolic process (GO:1902224)2.47634811
172glutamate metabolic process (GO:0006536)2.47533951
173adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.47474054
174fatty acid catabolic process (GO:0009062)2.46587320
175peptidyl-cysteine modification (GO:0018198)2.46486608
176purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.46294094
177tricarboxylic acid metabolic process (GO:0072350)2.45867452
178positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.45840936
179inner mitochondrial membrane organization (GO:0007007)2.45013342
180monosaccharide biosynthetic process (GO:0046364)2.44084436

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse5.09217331
2* ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.16472850
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.86340894
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.37146617
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.35988400
6EZH2_22144423_ChIP-Seq_EOC_Human3.21032919
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.03125518
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.88846197
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.65359469
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.45764850
11PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.39915802
12TAF15_26573619_Chip-Seq_HEK293_Human2.39571280
13* REST_18959480_ChIP-ChIP_MESCs_Mouse2.39038001
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.34023911
15RARB_27405468_Chip-Seq_BRAIN_Mouse2.28576332
16THAP11_20581084_ChIP-Seq_MESCs_Mouse2.28494877
17VDR_22108803_ChIP-Seq_LS180_Human2.28392895
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.27163532
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.18920038
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.17845838
21IGF1R_20145208_ChIP-Seq_DFB_Human2.09652851
22YY1_21170310_ChIP-Seq_MESCs_Mouse2.01379879
23REST_21632747_ChIP-Seq_MESCs_Mouse1.99011441
24* ETS1_20019798_ChIP-Seq_JURKAT_Human1.98275904
25* SRF_21415370_ChIP-Seq_HL-1_Mouse1.93317575
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.92684653
27GBX2_23144817_ChIP-Seq_PC3_Human1.91663821
28FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.83594150
29SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.74572377
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.71965964
31RXR_22158963_ChIP-Seq_LIVER_Mouse1.70009868
32NOTCH1_21737748_ChIP-Seq_TLL_Human1.67857078
33MYC_18940864_ChIP-ChIP_HL60_Human1.67695111
34TP53_22573176_ChIP-Seq_HFKS_Human1.67278477
35TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67055608
36PPARA_22158963_ChIP-Seq_LIVER_Mouse1.65674994
37MYC_18358816_ChIP-ChIP_MESCs_Mouse1.63244233
38* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.62700659
39SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.58057438
40CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.57273872
41KDM5A_27292631_Chip-Seq_BREAST_Human1.54870600
42CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.53026082
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48545976
44CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.48470589
45ELK1_19687146_ChIP-ChIP_HELA_Human1.47723677
46GABP_17652178_ChIP-ChIP_JURKAT_Human1.47086555
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.45456965
48ELF1_17652178_ChIP-ChIP_JURKAT_Human1.45113963
49CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.42876582
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.41418604
51ESR1_15608294_ChIP-ChIP_MCF-7_Human1.39823527
52DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.38891539
53ZNF274_21170338_ChIP-Seq_K562_Hela1.36693691
54SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.30966926
55ETV2_25802403_ChIP-Seq_MESCs_Mouse1.29813753
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.29680295
57HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.29310379
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28710009
59GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.27981457
60* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25797431
61DNAJC2_21179169_ChIP-ChIP_NT2_Human1.25545873
62E2F1_20622854_ChIP-Seq_HELA_Human1.25343157
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24187494
64RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23656252
65FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.23490026
66PHF8_20622854_ChIP-Seq_HELA_Human1.21502634
67RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.21481566
68CIITA_25753668_ChIP-Seq_RAJI_Human1.21183628
69XRN2_22483619_ChIP-Seq_HELA_Human1.19978145
70FLI1_27457419_Chip-Seq_LIVER_Mouse1.18279973
71EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17777007
72PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.17606710
73FOXP3_21729870_ChIP-Seq_TREG_Human1.17455753
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17336242
75GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.16911522
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.15571072
77E2F1_18555785_ChIP-Seq_MESCs_Mouse1.14684620
78CTCF_18555785_ChIP-Seq_MESCs_Mouse1.14286054
79TTF2_22483619_ChIP-Seq_HELA_Human1.14040228
80HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13320750
81MYC_19829295_ChIP-Seq_ESCs_Human1.12650509
82ELF1_20517297_ChIP-Seq_JURKAT_Human1.12456107
83LXR_22158963_ChIP-Seq_LIVER_Mouse1.11872254
84CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.11570223
85FOXP1_21924763_ChIP-Seq_HESCs_Human1.11533120
86RAC3_21632823_ChIP-Seq_H3396_Human1.11233541
87FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10879526
88LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.10393160
89SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10370369
90* OCT4_20526341_ChIP-Seq_ESCs_Human1.10157565
91CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.09760175
92BCL6_27268052_Chip-Seq_Bcells_Human1.08361046
93PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08237555
94* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07736948
95GABP_19822575_ChIP-Seq_HepG2_Human1.06839271
96DROSHA_22980978_ChIP-Seq_HELA_Human1.05976686
97MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05953715
98NCOR_22424771_ChIP-Seq_293T_Human1.05371362
99NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.03427166
100TBX5_21415370_ChIP-Seq_HL-1_Mouse1.02607998
101NANOG_20526341_ChIP-Seq_ESCs_Human1.02486812
102* TAF2_19829295_ChIP-Seq_ESCs_Human1.01673849
103BCOR_27268052_Chip-Seq_Bcells_Human1.01321282
104* HOXB7_26014856_ChIP-Seq_BT474_Human1.00796682
105FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00662100
106FOXA1_25329375_ChIP-Seq_VCAP_Human1.00662100
107EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.99265096
108EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.97873041
109LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.97583927
110SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.96488306
111YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96313877
112P53_21459846_ChIP-Seq_SAOS-2_Human0.96023232
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.95442996
114CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95400041
115GATA3_21878914_ChIP-Seq_MCF-7_Human0.95352764
116JARID2_20064375_ChIP-Seq_MESCs_Mouse0.95087983
117SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94489846
118YY1_22570637_ChIP-Seq_MALME-3M_Human0.94055922
119CTCF_20526341_ChIP-Seq_ESCs_Human0.93550231
120P300_27268052_Chip-Seq_Bcells_Human0.93379054
121HTT_18923047_ChIP-ChIP_STHdh_Human0.92953450
122SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.92160592
123EOMES_21245162_ChIP-Seq_HESCs_Human0.91986767
124SMC4_20622854_ChIP-Seq_HELA_Human0.91794506
125* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91635221
126SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.91276333
127FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.90397777
128MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.90105453
129MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.89722736
130IRF1_19129219_ChIP-ChIP_H3396_Human0.88872161
131AR_20517297_ChIP-Seq_VCAP_Human0.88119017
132CTCF_27219007_Chip-Seq_Bcells_Human0.87692561
133MYC_19030024_ChIP-ChIP_MESCs_Mouse0.85994512
134MTF2_20144788_ChIP-Seq_MESCs_Mouse0.84429768
135STAT1_20625510_ChIP-Seq_HELA_Human0.83860105
136NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.83466559
137MYC_18555785_ChIP-Seq_MESCs_Mouse0.83243790
138TET1_21451524_ChIP-Seq_MESCs_Mouse0.81169955
139CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.81024999
140ZFP281_18757296_ChIP-ChIP_E14_Mouse0.80857016
141EZH2_27304074_Chip-Seq_ESCs_Mouse0.80670324
142ZFX_18555785_ChIP-Seq_MESCs_Mouse0.79874341
143THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.79805348
144ZNF263_19887448_ChIP-Seq_K562_Human0.79583944
145P68_20966046_ChIP-Seq_HELA_Human0.79400009
146DCP1A_22483619_ChIP-Seq_HELA_Human0.79140053
147ERA_21632823_ChIP-Seq_H3396_Human0.79112641
148RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.78153944
149VDR_23849224_ChIP-Seq_CD4+_Human0.78122001
150JARID2_20075857_ChIP-Seq_MESCs_Mouse0.76787047

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue4.92014068
2MP0003880_abnormal_central_pattern4.51634197
3MP0004859_abnormal_synaptic_plasticity3.47158593
4MP0002837_dystrophic_cardiac_calcinosis3.37793176
5MP0009780_abnormal_chondrocyte_physiolo3.22491415
6MP0001986_abnormal_taste_sensitivity2.92376152
7MP0000751_myopathy2.82688271
8MP0003787_abnormal_imprinting2.82533595
9MP0004130_abnormal_muscle_cell2.68181948
10MP0005646_abnormal_pituitary_gland2.59355587
11MP0003635_abnormal_synaptic_transmissio2.57483576
12MP0006036_abnormal_mitochondrial_physio2.54459761
13MP0003186_abnormal_redox_activity2.42285165
14MP0004133_heterotaxia2.38852054
15MP0002876_abnormal_thyroid_physiology2.27761256
16MP0005084_abnormal_gallbladder_morpholo2.24584868
17MP0004215_abnormal_myocardial_fiber2.23817948
18MP0009840_abnormal_foam_cell2.20264675
19MP0009745_abnormal_behavioral_response2.18602302
20MP0002139_abnormal_hepatobiliary_system2.17442452
21MP0002063_abnormal_learning/memory/cond2.16064544
22MP0001529_abnormal_vocalization2.12364106
23MP0002064_seizures2.10998758
24MP0003329_amyloid_beta_deposits2.07705273
25MP0005551_abnormal_eye_electrophysiolog2.00709432
26MP0002254_reproductive_system_inflammat2.00498195
27MP0004036_abnormal_muscle_relaxation1.99511950
28MP0009046_muscle_twitch1.95366513
29MP0006072_abnormal_retinal_apoptosis1.94084614
30MP0005075_abnormal_melanosome_morpholog1.89851258
31MP0002822_catalepsy1.82763163
32MP0002736_abnormal_nociception_after1.82748751
33MP0003656_abnormal_erythrocyte_physiolo1.81836470
34MP0003806_abnormal_nucleotide_metabolis1.80501072
35MP0002272_abnormal_nervous_system1.79754089
36MP0006276_abnormal_autonomic_nervous1.78279338
37MP0004147_increased_porphyrin_level1.74226307
38MP0003879_abnormal_hair_cell1.73096975
39MP0003011_delayed_dark_adaptation1.72225807
40MP0001968_abnormal_touch/_nociception1.71209522
41MP0005085_abnormal_gallbladder_physiolo1.71068705
42MP0008789_abnormal_olfactory_epithelium1.70859857
43MP0000749_muscle_degeneration1.68274697
44MP0010329_abnormal_lipoprotein_level1.65644795
45MP0008058_abnormal_DNA_repair1.65491968
46MP0008004_abnormal_stomach_pH1.64713543
47MP0003690_abnormal_glial_cell1.64390182
48MP0001440_abnormal_grooming_behavior1.63234044
49MP0006292_abnormal_olfactory_placode1.61950979
50MP0005360_urolithiasis1.61219159
51MP0003183_abnormal_peptide_metabolism1.60403643
52MP0005083_abnormal_biliary_tract1.59766839
53MP0004270_analgesia1.59298521
54MP0005365_abnormal_bile_salt1.58848152
55MP0001984_abnormal_olfaction1.56499704
56MP0006035_abnormal_mitochondrial_morpho1.56342043
57MP0002572_abnormal_emotion/affect_behav1.55947590
58MP0003137_abnormal_impulse_conducting1.50262775
59MP0002653_abnormal_ependyma_morphology1.50207324
60MP0000604_amyloidosis1.44034048
61MP0005253_abnormal_eye_physiology1.43112712
62MP0004924_abnormal_behavior1.40945804
63MP0005386_behavior/neurological_phenoty1.40945804
64MP0005645_abnormal_hypothalamus_physiol1.40513137
65MP0005670_abnormal_white_adipose1.39952252
66MP0008995_early_reproductive_senescence1.38936299
67MP0000747_muscle_weakness1.37160310
68MP0003136_yellow_coat_color1.33824380
69MP0002269_muscular_atrophy1.33489172
70MP0001905_abnormal_dopamine_level1.31389089
71MP0004043_abnormal_pH_regulation1.31358619
72MP0008875_abnormal_xenobiotic_pharmacok1.30403257
73MP0002909_abnormal_adrenal_gland1.29470270
74MP0004084_abnormal_cardiac_muscle1.28300934
75MP0001501_abnormal_sleep_pattern1.26461734
76MP0002332_abnormal_exercise_endurance1.24438258
77MP0005330_cardiomyopathy1.23420530
78MP0005167_abnormal_blood-brain_barrier1.23020718
79MP0003718_maternal_effect1.22039136
80MP0004085_abnormal_heartbeat1.21507526
81MP0005499_abnormal_olfactory_system1.21366660
82MP0005394_taste/olfaction_phenotype1.21366660
83MP0004019_abnormal_vitamin_homeostasis1.21161363
84MP0002972_abnormal_cardiac_muscle1.20552988
85MP0002928_abnormal_bile_duct1.19022727
86MP0001486_abnormal_startle_reflex1.17855919
87MP0004858_abnormal_nervous_system1.16640744
88MP0005584_abnormal_enzyme/coenzyme_acti1.16062235
89MP0000631_abnormal_neuroendocrine_gland1.14660840
90MP0005332_abnormal_amino_acid1.13639284
91MP0003123_paternal_imprinting1.13121990
92MP0005620_abnormal_muscle_contractility1.13047831
93MP0000015_abnormal_ear_pigmentation1.10256945
94MP0002210_abnormal_sex_determination1.08914509
95MP0002106_abnormal_muscle_physiology1.08453728
96MP0003786_premature_aging1.07490193
97MP0001485_abnormal_pinna_reflex1.07399417
98MP0008260_abnormal_autophagy1.04478500
99MP0004145_abnormal_muscle_electrophysio1.04337692
100MP0002067_abnormal_sensory_capabilities1.04316443
101MP0003121_genomic_imprinting1.04306705
102MP0002735_abnormal_chemical_nociception1.03196566
103MP0005389_reproductive_system_phenotype1.03159932
104MP0003303_peritoneal_inflammation1.02853439
105MP0000013_abnormal_adipose_tissue1.02795429
106MP0001970_abnormal_pain_threshold1.02794796
107MP0010386_abnormal_urinary_bladder1.01544925
108MP0002160_abnormal_reproductive_system1.00592194
109MP0000778_abnormal_nervous_system0.99702572
110MP0004885_abnormal_endolymph0.99122243
111MP0003698_abnormal_male_reproductive0.97659296
112MP0002734_abnormal_mechanical_nocicepti0.97489336
113MP0008569_lethality_at_weaning0.97409733
114MP0003221_abnormal_cardiomyocyte_apopto0.97385027
115MP0004142_abnormal_muscle_tone0.97331226
116MP0005266_abnormal_metabolism0.97222647
117MP0002229_neurodegeneration0.96638386
118MP0008775_abnormal_heart_ventricle0.96478483
119MP0000358_abnormal_cell_content/0.96132451
120MP0002066_abnormal_motor_capabilities/c0.95449424
121MP0005535_abnormal_body_temperature0.95379680
122MP0001929_abnormal_gametogenesis0.94718463
123MP0002733_abnormal_thermal_nociception0.93691938
124MP0000427_abnormal_hair_cycle0.93510996
125MP0005423_abnormal_somatic_nervous0.91804496
126MP0001544_abnormal_cardiovascular_syste0.90798488
127MP0005385_cardiovascular_system_phenoty0.90798488
128MP0003938_abnormal_ear_development0.90514134
129MP0008874_decreased_physiological_sensi0.90351177
130MP0004087_abnormal_muscle_fiber0.89351336
131MP0005636_abnormal_mineral_homeostasis0.88892803
132MP0004811_abnormal_neuron_physiology0.88577647
133MP0003191_abnormal_cellular_cholesterol0.87464112
134MP0003567_abnormal_fetal_cardiomyocyte0.87377369
135MP0004233_abnormal_muscle_weight0.87271934
136MP0001944_abnormal_pancreas_morphology0.87180408
137MP0005369_muscle_phenotype0.86999628
138MP0003633_abnormal_nervous_system0.85844923
139MP0005220_abnormal_exocrine_pancreas0.85584432
140MP0008872_abnormal_physiological_respon0.84341014
141MP0002557_abnormal_social/conspecific_i0.83969581
142MP0001853_heart_inflammation0.83044918
143MP0001756_abnormal_urination0.82329814
144MP0002102_abnormal_ear_morphology0.81252074
145MP0002118_abnormal_lipid_homeostasis0.80897497
146MP0008877_abnormal_DNA_methylation0.80636181
147MP0008007_abnormal_cellular_replicative0.80275111
148MP0002095_abnormal_skin_pigmentation0.79834609
149MP0001145_abnormal_male_reproductive0.79088994
150MP0001324_abnormal_eye_pigmentation0.78258502
151MP0009697_abnormal_copulation0.78143543
152MP0009643_abnormal_urine_homeostasis0.76300444
153MP0003172_abnormal_lysosome_physiology0.76020488
154MP0002069_abnormal_eating/drinking_beha0.75578830
155MP0001764_abnormal_homeostasis0.75177682
156MP0003631_nervous_system_phenotype0.74103057
157MP0000750_abnormal_muscle_regeneration0.73747851
158MP0005319_abnormal_enzyme/_coenzyme0.71141828

Predicted human phenotypes

RankGene SetZ-score
1Abnormal mitochondria in muscle tissue (HP:0008316)4.20246636
2Acute necrotizing encephalopathy (HP:0006965)4.14430363
3Hepatocellular necrosis (HP:0001404)4.01559046
4Myokymia (HP:0002411)3.94269265
5Hepatic necrosis (HP:0002605)3.89730749
6Focal motor seizures (HP:0011153)3.89197544
7Neuroendocrine neoplasm (HP:0100634)3.85870271
8Increased serum pyruvate (HP:0003542)3.81056023
9Abnormality of glycolysis (HP:0004366)3.81056023
10Pheochromocytoma (HP:0002666)3.80614690
11Acute encephalopathy (HP:0006846)3.71474434
12Mitochondrial inheritance (HP:0001427)3.66304950
13Broad alveolar ridges (HP:0000187)3.49405497
14Increased CSF lactate (HP:0002490)3.45011397
15Esophageal neoplasm (HP:0100751)3.44502182
16Neoplasm of head and neck (HP:0012288)3.44502182
17Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.35000854
183-Methylglutaconic aciduria (HP:0003535)3.28393075
19Atonic seizures (HP:0010819)3.23643787
20Progressive macrocephaly (HP:0004481)3.21799225
21Abnormality of fatty-acid metabolism (HP:0004359)3.17160604
22Cerebral edema (HP:0002181)3.14990331
23Nephronophthisis (HP:0000090)3.13054014
24Pancreatic cysts (HP:0001737)3.06531074
25Hyperventilation (HP:0002883)3.04195641
26Tubulointerstitial nephritis (HP:0001970)3.03482095
27Atrioventricular block (HP:0001678)2.98864126
28Hyperlipoproteinemia (HP:0010980)2.96103258
29Lactic acidosis (HP:0003128)2.91444430
30Abnormal number of erythroid precursors (HP:0012131)2.88968849
31True hermaphroditism (HP:0010459)2.86726179
32Pancreatic fibrosis (HP:0100732)2.85691839
33Renal Fanconi syndrome (HP:0001994)2.84664879
34Abnormality of alanine metabolism (HP:0010916)2.82117377
35Hyperalaninemia (HP:0003348)2.82117377
36Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.82117377
37Abnormality of the renal medulla (HP:0100957)2.75405440
38Medial flaring of the eyebrow (HP:0010747)2.74687034
39Exercise-induced myalgia (HP:0003738)2.70037447
40Type II lissencephaly (HP:0007260)2.68747036
41Epileptic encephalopathy (HP:0200134)2.68395424
42Febrile seizures (HP:0002373)2.66868223
43Exercise-induced muscle cramps (HP:0003710)2.66056741
44Abnormality of midbrain morphology (HP:0002418)2.65844485
45Molar tooth sign on MRI (HP:0002419)2.65844485
46Microvesicular hepatic steatosis (HP:0001414)2.65087670
47Exercise intolerance (HP:0003546)2.64307542
48Myoglobinuria (HP:0002913)2.61937371
49Increased serum lactate (HP:0002151)2.58788914
50Ragged-red muscle fibers (HP:0003200)2.58771045
51Focal seizures (HP:0007359)2.57149362
52Methylmalonic aciduria (HP:0012120)2.49434285
53Respiratory failure (HP:0002878)2.49429703
54Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.48627858
55Ketoacidosis (HP:0001993)2.48186304
56Visual hallucinations (HP:0002367)2.47517226
57CNS demyelination (HP:0007305)2.46467792
58Neoplasm of the peripheral nervous system (HP:0100007)2.46442687
59Heart block (HP:0012722)2.45456602
60Increased hepatocellular lipid droplets (HP:0006565)2.45272983
61Abnormality of cells of the erythroid lineage (HP:0012130)2.45253416
62Hyperammonemia (HP:0001987)2.43052780
63Abolished electroretinogram (ERG) (HP:0000550)2.41409258
64Chronic hepatic failure (HP:0100626)2.40867056
65Methylmalonic acidemia (HP:0002912)2.40692713
66Abnormality of the labia minora (HP:0012880)2.38392919
67Increased muscle lipid content (HP:0009058)2.35621755
68Concave nail (HP:0001598)2.33112367
69Hypoplastic left heart (HP:0004383)2.32056228
70Ketosis (HP:0001946)2.30097051
71Cholelithiasis (HP:0001081)2.27460131
72Absence seizures (HP:0002121)2.27408226
73Palpitations (HP:0001962)2.24227523
74Impaired vibration sensation in the lower limbs (HP:0002166)2.22723733
75Pendular nystagmus (HP:0012043)2.22486569
76Abnormal gallbladder physiology (HP:0012438)2.21616491
77Cholecystitis (HP:0001082)2.21616491
78Respiratory difficulties (HP:0002880)2.20470922
79Abnormality of the renal cortex (HP:0011035)2.19949188
80Hypoalphalipoproteinemia (HP:0003233)2.19276533
81Lethargy (HP:0001254)2.18555621
82Lipid accumulation in hepatocytes (HP:0006561)2.18302435
83Dicarboxylic aciduria (HP:0003215)2.18193006
84Abnormality of dicarboxylic acid metabolism (HP:0010995)2.18193006
85Cystic liver disease (HP:0006706)2.18147559
86Delayed CNS myelination (HP:0002188)2.17503422
87Abnormality of the lower motor neuron (HP:0002366)2.16819045
88Nephrogenic diabetes insipidus (HP:0009806)2.16520281
89Abnormality of the heme biosynthetic pathway (HP:0010472)2.15761174
90Paraparesis (HP:0002385)2.15423103
91Abnormal atrioventricular conduction (HP:0005150)2.14336420
92Congenital primary aphakia (HP:0007707)2.14280465
93Sclerocornea (HP:0000647)2.13915684
94Emotional lability (HP:0000712)2.13813044
95Gait imbalance (HP:0002141)2.13542864
96Oligomenorrhea (HP:0000876)2.13154218
97Increased intramyocellular lipid droplets (HP:0012240)2.13148880
98Decreased activity of mitochondrial respiratory chain (HP:0008972)2.13074300
99Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.13074300
100Congenital hepatic fibrosis (HP:0002612)2.10805700
101Anxiety (HP:0000739)2.09818832
102Leukodystrophy (HP:0002415)2.09477149
103Polyphagia (HP:0002591)2.09262634
104Epiphyseal stippling (HP:0010655)2.08805294
105Agitation (HP:0000713)2.08782030
106Abnormality of serine family amino acid metabolism (HP:0010894)2.08117473
107Abnormality of glycine metabolism (HP:0010895)2.08117473
108Poor suck (HP:0002033)2.06922325
109Abnormal gallbladder morphology (HP:0012437)2.06718991
110Thyroid-stimulating hormone excess (HP:0002925)2.06434604
111Dialeptic seizures (HP:0011146)2.06194771
112Calf muscle hypertrophy (HP:0008981)2.06059667
113Tetraparesis (HP:0002273)2.06005157
114Aplasia involving bones of the upper limbs (HP:0009823)2.05540756
115Aplasia of the phalanges of the hand (HP:0009802)2.05540756
116Aplasia involving bones of the extremities (HP:0009825)2.05540756
117Sudden death (HP:0001699)2.05442297
118Fetal akinesia sequence (HP:0001989)2.05247235
119Muscle hypertrophy of the lower extremities (HP:0008968)2.05018150
120Abnormal drinking behavior (HP:0030082)2.04309754
121Polydipsia (HP:0001959)2.04309754
122Retinal dysplasia (HP:0007973)2.03948521
123Broad-based gait (HP:0002136)2.03849962
124Dry hair (HP:0011359)2.03392006
125Abnormal rod and cone electroretinograms (HP:0008323)2.03044657
126Generalized tonic-clonic seizures (HP:0002069)2.02270817
127Poor eye contact (HP:0000817)2.01897240
128Neoplasm of the adrenal gland (HP:0100631)2.01307138
129Severe visual impairment (HP:0001141)2.01081591
130Tinnitus (HP:0000360)2.00998090
131Brushfield spots (HP:0001088)2.00816231
132Hyperglycinemia (HP:0002154)2.00584361
133Renal cortical cysts (HP:0000803)1.99563525
134Abnormality of the alveolar ridges (HP:0006477)1.97580577
135Ankle clonus (HP:0011448)1.97037033
136Gout (HP:0001997)1.96884508
137Inability to walk (HP:0002540)1.96784854
138Abnormality of renal resorption (HP:0011038)1.96349721
139Tubular atrophy (HP:0000092)1.96304700
140Hyperglycinuria (HP:0003108)1.96005263
141Impaired social interactions (HP:0000735)1.94918246
142Abnormal social behavior (HP:0012433)1.94918246
143Testicular neoplasm (HP:0010788)1.94814591
144Type I transferrin isoform profile (HP:0003642)1.93364135
145Optic disc pallor (HP:0000543)1.93338682
146Exertional dyspnea (HP:0002875)1.91702516
147Congenital stationary night blindness (HP:0007642)1.89622038
148Progressive microcephaly (HP:0000253)1.89295044
149Aplasia/hypoplasia of the uterus (HP:0008684)1.88819056
150Opisthotonus (HP:0002179)1.88696514
151Prolonged QT interval (HP:0001657)1.87126068
152CNS hypomyelination (HP:0003429)1.86123014
153Hypomagnesemia (HP:0002917)1.85347106
154Metabolic acidosis (HP:0001942)1.84301557
155Severe muscular hypotonia (HP:0006829)1.84040076
156Poor speech (HP:0002465)1.84028383
157Attenuation of retinal blood vessels (HP:0007843)1.81912683
158Bile duct proliferation (HP:0001408)1.81702771
159Abnormal biliary tract physiology (HP:0012439)1.81702771
160Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.79758833
161Aplasia/Hypoplasia of the spleen (HP:0010451)1.78904605
162Intestinal atresia (HP:0011100)1.78336600
163Tubulointerstitial abnormality (HP:0001969)1.74899590
164Polyuria (HP:0000103)1.74231560
165Limb hypertonia (HP:0002509)1.73339497
166Absent rod-and cone-mediated responses on ERG (HP:0007688)1.73086970

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K5.23011628
2MAPKAPK34.82644990
3MAP4K23.19903430
4MAP3K123.16557840
5DAPK13.03643211
6VRK22.98146336
7WNK42.77951852
8MAPKAPK52.39170949
9PDK32.36436665
10PDK42.36436665
11MAP2K62.31007776
12DAPK22.14258427
13MAP3K112.12527527
14MAPK132.10903969
15MAPK122.08861129
16EPHA42.08571291
17CDK192.08026425
18FRK2.07378544
19INSRR2.00536733
20CCNB11.97086204
21PRPF4B1.96524931
22RPS6KA21.96515330
23GRK11.95201828
24BCKDK1.88863995
25MAP3K41.80997845
26MAP2K71.79393173
27TSSK61.78181394
28CASK1.78144131
29TLK11.78079663
30TAOK31.72653606
31ZAK1.70331936
32MAP3K61.68197764
33TNK21.67862159
34MYLK1.65741333
35NUAK11.63105234
36KDR1.51374792
37PRKCG1.42510055
38EIF2AK11.41184824
39MINK11.36930171
40DYRK21.33863117
41VRK11.32479255
42NTRK31.29232126
43ARAF1.27453278
44PDK21.26795974
45PINK11.24949763
46PHKG11.24798959
47PHKG21.24798959
48MARK11.22564099
49NEK11.22147214
50CAMK1D1.20622796
51NME11.15752777
52CAMKK21.14233819
53NTRK21.12765297
54TAOK21.11778595
55MAP4K11.11166750
56BRSK11.08101844
57MAPK71.05629732
58SCYL21.03875428
59TESK11.03700504
60ZAP701.02046201
61LMTK21.01157823
62PRKCI1.00795514
63MAP3K90.98790947
64MAP2K40.98473353
65ADRBK10.97573159
66RPS6KB20.95652924
67STK160.95304859
68RPS6KC10.94322328
69RPS6KL10.94322328
70MAP2K30.93568445
71DAPK30.92775722
72TRPM70.92704661
73PTK2B0.92549494
74BMPR1B0.92017628
75RPS6KB10.92017088
76SGK20.87705724
77RPS6KA60.83150138
78MAP2K20.81763355
79IKBKB0.81589721
80TAF10.80651601
81SGK4940.80643216
82SGK2230.80643216
83CSNK1G10.77952885
84MAPK110.77929160
85PIM20.77251442
86PASK0.77102758
87ITK0.73456696
88STK390.73318873
89CSNK1G20.73189268
90OXSR10.72756431
91FES0.72653514
92MAP3K50.72582866
93CAMKK10.72350003
94OBSCN0.71494671
95MARK30.71105295
96CDK50.70476910
97RPS6KA50.69581908
98TEC0.66727449
99PRKD30.66484137
100CAMK2B0.66203166
101GRK70.66187834
102BRAF0.65933741
103CAMK10.65045176
104TTN0.64721346
105CDK180.62941253
106WNK30.61977303
107ATR0.61267878
108CSNK1G30.60683877
109CDK150.58531145
110CSNK1A1L0.57341440
111CAMK2A0.56670111
112TYRO30.55941973
113CAMK1G0.55163032
114FGFR20.54953147
115IRAK10.54626288
116CDK11A0.53614614
117TNIK0.53227697
118SIK20.53045096
119STK110.52765055
120SGK30.52043193
121RAF10.51684082
122PRKCZ0.51396556
123CSNK1A10.50251402
124BTK0.49851618
125MAPK40.49191191
126DYRK1A0.49085356
127UHMK10.46785120
128PAK40.46677011
129CDK140.45485327
130ADRBK20.45311030
131LIMK10.45134527
132DYRK30.44822222
133CAMK2G0.43550914
134MAPK150.43321618
135PLK20.42567971
136MST40.42431625
137AKT30.41922250
138PNCK0.41252821
139PRKCE0.39903899
140KSR20.39669718
141PDK10.38952016
142ILK0.38409358
143ALK0.37500564
144TIE10.37072416
145ATM0.36883198
146BRSK20.34790862
147WEE10.34682063
148GRK50.34249990
149CAMK40.33706463
150PLK30.33591126
151PRKAA10.33578575
152LYN0.33220494
153IRAK20.32936765
154FGFR40.32306704
155PRKACA0.32019640
156TGFBR10.31713822
157SYK0.31019727
158PAK30.30787814
159BCR0.30753059
160PDPK10.30268342
161CHUK0.30154573
162TXK0.29892649

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.91763598
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.97352881
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.76774024
4Oxidative phosphorylation_Homo sapiens_hsa001903.04509516
5Parkinsons disease_Homo sapiens_hsa050122.77953499
6Pyruvate metabolism_Homo sapiens_hsa006202.56107387
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.50669386
8Propanoate metabolism_Homo sapiens_hsa006402.44256385
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.40539929
10Carbon metabolism_Homo sapiens_hsa012002.35387246
11Ribosome_Homo sapiens_hsa030102.33923376
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.11716959
13Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002502.09144412
14Phototransduction_Homo sapiens_hsa047442.06146322
15Synaptic vesicle cycle_Homo sapiens_hsa047212.00181289
16Butanoate metabolism_Homo sapiens_hsa006502.00162768
17Alzheimers disease_Homo sapiens_hsa050101.96258736
18Biosynthesis of amino acids_Homo sapiens_hsa012301.88182761
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.88181511
20Basal transcription factors_Homo sapiens_hsa030221.87845019
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.81993427
22Fatty acid degradation_Homo sapiens_hsa000711.81740463
23Selenocompound metabolism_Homo sapiens_hsa004501.81326985
24Arginine biosynthesis_Homo sapiens_hsa002201.78934073
25Homologous recombination_Homo sapiens_hsa034401.76477308
26Protein export_Homo sapiens_hsa030601.73119998
27One carbon pool by folate_Homo sapiens_hsa006701.72374553
28Fanconi anemia pathway_Homo sapiens_hsa034601.64386983
29Cardiac muscle contraction_Homo sapiens_hsa042601.63522880
30Huntingtons disease_Homo sapiens_hsa050161.62602947
31Olfactory transduction_Homo sapiens_hsa047401.60968506
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.59479687
33Collecting duct acid secretion_Homo sapiens_hsa049661.57989467
34Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.57684504
35Fatty acid metabolism_Homo sapiens_hsa012121.55576383
36Base excision repair_Homo sapiens_hsa034101.51669231
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.49601715
38Primary bile acid biosynthesis_Homo sapiens_hsa001201.47134056
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.46570827
40Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.46148674
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.45486429
42Nicotine addiction_Homo sapiens_hsa050331.41760993
43Steroid biosynthesis_Homo sapiens_hsa001001.41507178
44Fatty acid elongation_Homo sapiens_hsa000621.41092413
45GABAergic synapse_Homo sapiens_hsa047271.40350299
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.37215730
47Pyrimidine metabolism_Homo sapiens_hsa002401.26981044
48Asthma_Homo sapiens_hsa053101.18344327
49Peroxisome_Homo sapiens_hsa041461.17608275
50Morphine addiction_Homo sapiens_hsa050321.17319411
51Circadian entrainment_Homo sapiens_hsa047131.16700070
52Linoleic acid metabolism_Homo sapiens_hsa005911.16239879
53Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.16093954
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.13793424
55Ether lipid metabolism_Homo sapiens_hsa005651.12479360
56Intestinal immune network for IgA production_Homo sapiens_hsa046721.10717694
57Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.10649770
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.10133952
59Glutathione metabolism_Homo sapiens_hsa004801.08902300
60PPAR signaling pathway_Homo sapiens_hsa033201.07303650
61Vitamin B6 metabolism_Homo sapiens_hsa007501.06853148
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.05728901
63Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.05447823
64RNA transport_Homo sapiens_hsa030131.01674436
65Vibrio cholerae infection_Homo sapiens_hsa051100.98551315
66RNA degradation_Homo sapiens_hsa030180.97978507
67Fructose and mannose metabolism_Homo sapiens_hsa000510.97403453
68Nitrogen metabolism_Homo sapiens_hsa009100.96010737
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.94837094
70Type I diabetes mellitus_Homo sapiens_hsa049400.94064439
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.93846847
72beta-Alanine metabolism_Homo sapiens_hsa004100.88848240
73Dopaminergic synapse_Homo sapiens_hsa047280.87500799
74Tryptophan metabolism_Homo sapiens_hsa003800.84875633
75Nucleotide excision repair_Homo sapiens_hsa034200.83790432
76Pentose phosphate pathway_Homo sapiens_hsa000300.83642643
77Glutamatergic synapse_Homo sapiens_hsa047240.82810028
78Amphetamine addiction_Homo sapiens_hsa050310.80675156
79Long-term potentiation_Homo sapiens_hsa047200.74936500
80Metabolic pathways_Homo sapiens_hsa011000.73805503
81Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.72886354
82Arginine and proline metabolism_Homo sapiens_hsa003300.71562317
83Phenylalanine metabolism_Homo sapiens_hsa003600.69255312
84Cyanoamino acid metabolism_Homo sapiens_hsa004600.67354992
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.66217479
86Lysosome_Homo sapiens_hsa041420.66196263
87Drug metabolism - other enzymes_Homo sapiens_hsa009830.65894977
88Folate biosynthesis_Homo sapiens_hsa007900.65732834
89SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64533493
90Allograft rejection_Homo sapiens_hsa053300.62981674
91Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.58834430
92Glucagon signaling pathway_Homo sapiens_hsa049220.58279947
93Proteasome_Homo sapiens_hsa030500.57563558
94Calcium signaling pathway_Homo sapiens_hsa040200.57350876
95Non-homologous end-joining_Homo sapiens_hsa034500.56013627
96Sulfur relay system_Homo sapiens_hsa041220.55656121
97Autoimmune thyroid disease_Homo sapiens_hsa053200.55642237
98Insulin secretion_Homo sapiens_hsa049110.53598659
99Bile secretion_Homo sapiens_hsa049760.53561285
100Chemical carcinogenesis_Homo sapiens_hsa052040.53546391
101Primary immunodeficiency_Homo sapiens_hsa053400.52587285
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.51985404
103Salivary secretion_Homo sapiens_hsa049700.50912387
104Glycerolipid metabolism_Homo sapiens_hsa005610.50330737
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48963179
106Renin secretion_Homo sapiens_hsa049240.47929815
107DNA replication_Homo sapiens_hsa030300.45321816
108Arachidonic acid metabolism_Homo sapiens_hsa005900.45146605
109Spliceosome_Homo sapiens_hsa030400.44937465
110Taste transduction_Homo sapiens_hsa047420.44652543
111Glycosaminoglycan degradation_Homo sapiens_hsa005310.43969746
112Other glycan degradation_Homo sapiens_hsa005110.43589207
113Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43489397
114Gap junction_Homo sapiens_hsa045400.43349890
115Tyrosine metabolism_Homo sapiens_hsa003500.43000913
116Serotonergic synapse_Homo sapiens_hsa047260.42574695
117Gastric acid secretion_Homo sapiens_hsa049710.42425083
118Cholinergic synapse_Homo sapiens_hsa047250.42381706
119Fat digestion and absorption_Homo sapiens_hsa049750.41997367
120Sulfur metabolism_Homo sapiens_hsa009200.41973154
121Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.41659972
122Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41440184
123Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40983088
124Graft-versus-host disease_Homo sapiens_hsa053320.40879007
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.40490442
126Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.40340872
127Mismatch repair_Homo sapiens_hsa034300.39775929
128Rheumatoid arthritis_Homo sapiens_hsa053230.39570097
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38765751
130Retinol metabolism_Homo sapiens_hsa008300.37411367
131Galactose metabolism_Homo sapiens_hsa000520.36855387
132Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36491583
133Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35325651
134Oxytocin signaling pathway_Homo sapiens_hsa049210.34233868
135N-Glycan biosynthesis_Homo sapiens_hsa005100.33849715
136Purine metabolism_Homo sapiens_hsa002300.32760882
137Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.32752076
138Glycerophospholipid metabolism_Homo sapiens_hsa005640.32486796
139Adipocytokine signaling pathway_Homo sapiens_hsa049200.31792734
140Dilated cardiomyopathy_Homo sapiens_hsa054140.31091923
141Histidine metabolism_Homo sapiens_hsa003400.30159528
142Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.29417589
143Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27125808
144Fatty acid biosynthesis_Homo sapiens_hsa000610.26962757
145Starch and sucrose metabolism_Homo sapiens_hsa005000.26933055
146RNA polymerase_Homo sapiens_hsa030200.26278518
147Cocaine addiction_Homo sapiens_hsa050300.24879290
148Insulin signaling pathway_Homo sapiens_hsa049100.24606585
149Regulation of autophagy_Homo sapiens_hsa041400.24001618
150Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23806726
151AMPK signaling pathway_Homo sapiens_hsa041520.21087269

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