ADGRE1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation by symbiont of host defense response (GO:0052509)8.01311785
2modulation by symbiont of host defense response (GO:0052031)8.01311785
3modulation by organism of immune response of other organism involved in symbiotic interaction (GO:008.01311785
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:08.01311785
5positive regulation by organism of defense response of other organism involved in symbiotic interact8.01311785
6modulation by symbiont of host immune response (GO:0052553)8.01311785
7regulation of interferon-beta biosynthetic process (GO:0045357)6.59949743
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.10931869
9macrophage activation involved in immune response (GO:0002281)5.90631693
10microglial cell activation (GO:0001774)5.50086435
11positive regulation of interleukin-8 biosynthetic process (GO:0045416)5.43746793
12positive regulation of interferon-alpha production (GO:0032727)5.43300154
13response to immune response of other organism involved in symbiotic interaction (GO:0052564)5.20290753
14response to host immune response (GO:0052572)5.20290753
15neutrophil activation involved in immune response (GO:0002283)5.19172921
16regulation of interferon-alpha production (GO:0032647)5.15355312
17response to peptidoglycan (GO:0032494)5.07647872
18response to host (GO:0075136)4.72961017
19response to host defenses (GO:0052200)4.72961017
20response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.72961017
21macrophage activation (GO:0042116)4.49390895
22detection of other organism (GO:0098543)4.46807293
23immunoglobulin mediated immune response (GO:0016064)4.41006533
24positive regulation of antigen processing and presentation (GO:0002579)4.40871228
25respiratory burst (GO:0045730)4.34874190
26leukocyte aggregation (GO:0070486)4.28533515
27regulation of gamma-delta T cell activation (GO:0046643)4.24483986
28regulation of B cell receptor signaling pathway (GO:0050855)4.17168230
29detection of bacterium (GO:0016045)4.14438220
30positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.03275909
31myeloid cell activation involved in immune response (GO:0002275)3.94819899
32detection of external biotic stimulus (GO:0098581)3.93989787
33regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.91021225
34detection of molecule of bacterial origin (GO:0032490)3.82383557
35I-kappaB phosphorylation (GO:0007252)3.80543345
36regulation of antigen processing and presentation (GO:0002577)3.71878789
37positive regulation of interferon-beta production (GO:0032728)3.70393168
38cellular extravasation (GO:0045123)3.66314244
39negative regulation of lymphocyte mediated immunity (GO:0002707)3.66072464
40regulation of interleukin-8 biosynthetic process (GO:0045414)3.65992893
41leukocyte migration involved in inflammatory response (GO:0002523)3.64878453
42regulation of mononuclear cell migration (GO:0071675)3.63567855
43pinocytosis (GO:0006907)3.63436758
44negative regulation of T cell mediated immunity (GO:0002710)3.61100066
45production of molecular mediator involved in inflammatory response (GO:0002532)3.59958269
46regulation of dendritic cell antigen processing and presentation (GO:0002604)3.58205621
47regulation of cholesterol storage (GO:0010885)3.56700424
48detection of biotic stimulus (GO:0009595)3.54159978
49lipopolysaccharide-mediated signaling pathway (GO:0031663)3.49103159
50granulocyte activation (GO:0036230)3.48458948
51response to muramyl dipeptide (GO:0032495)3.45290357
52positive regulation of cellular amide metabolic process (GO:0034250)3.42561027
53positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.42143627
54regulation of mast cell degranulation (GO:0043304)3.40717016
55regulation of gamma-delta T cell differentiation (GO:0045586)3.40438970
56positive regulation of mast cell activation (GO:0033005)3.40296453
57positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.39035967
58apoptotic cell clearance (GO:0043277)3.36399158
59neutrophil activation (GO:0042119)3.35817270
60hydrogen peroxide biosynthetic process (GO:0050665)3.33090888
61negative regulation of leukocyte mediated immunity (GO:0002704)3.31833532
62regulation of tolerance induction (GO:0002643)3.30665639
63negative regulation of cell killing (GO:0031342)3.30280647
64negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.30280647
65positive regulation of gamma-delta T cell activation (GO:0046645)3.29886016
66negative regulation of interleukin-17 production (GO:0032700)3.29839670
67defense response to protozoan (GO:0042832)3.28718258
68negative regulation of erythrocyte differentiation (GO:0045647)3.26952848
69regulation of T cell tolerance induction (GO:0002664)3.25587390
70regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.24791851
71regulation of mast cell activation involved in immune response (GO:0033006)3.23059697
72leukocyte degranulation (GO:0043299)3.19466515
73regulation of mast cell activation (GO:0033003)3.18265172
74lymphocyte chemotaxis (GO:0048247)3.18133281
75regulation of T-helper 2 cell differentiation (GO:0045628)3.15798783
76negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.12739461
77negative regulation of interleukin-12 production (GO:0032695)3.11915569
78B cell mediated immunity (GO:0019724)3.10689526
79negative regulation of cytokine production involved in immune response (GO:0002719)3.09347035
80positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.08923633
81neutrophil mediated immunity (GO:0002446)3.08649742
82T cell migration (GO:0072678)3.05105700
83negative regulation of mast cell activation (GO:0033004)3.04676226
84response to protozoan (GO:0001562)3.03712468
85B cell receptor signaling pathway (GO:0050853)3.02693254
86positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.02507776
87positive regulation of type 2 immune response (GO:0002830)3.01885499
88mannose metabolic process (GO:0006013)3.01606720
89germinal center formation (GO:0002467)2.99810542
90response to interleukin-15 (GO:0070672)2.99353632
91positive regulation of mast cell degranulation (GO:0043306)2.99149801
92positive regulation of mast cell activation involved in immune response (GO:0033008)2.99149801
93regulation of integrin activation (GO:0033623)2.98909099
94regulation of leukocyte degranulation (GO:0043300)2.98091042
95regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.97525655
96positive regulation of tolerance induction (GO:0002645)2.96965238
97myeloid leukocyte mediated immunity (GO:0002444)2.94888505
98low-density lipoprotein particle clearance (GO:0034383)2.94454166
99regulation of macrophage chemotaxis (GO:0010758)2.94080390
100positive regulation of chemokine biosynthetic process (GO:0045080)2.94016597
101negative regulation of granulocyte differentiation (GO:0030853)2.93250974
102tolerance induction (GO:0002507)2.92440544
103positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.90979418
104reactive oxygen species biosynthetic process (GO:1903409)2.90962214
105regulation of regulatory T cell differentiation (GO:0045589)2.89759373
106positive regulation of leukocyte degranulation (GO:0043302)2.89631382
107regulation of T-helper 1 cell differentiation (GO:0045625)2.89575938
108negative regulation of interleukin-6 production (GO:0032715)2.88994565
109superoxide anion generation (GO:0042554)2.88470953
110regulation of B cell differentiation (GO:0045577)2.88325317
111myeloid leukocyte activation (GO:0002274)2.87835832
112type I interferon signaling pathway (GO:0060337)2.87718227
113cellular response to type I interferon (GO:0071357)2.87718227
114regulation of regulated secretory pathway (GO:1903305)2.87621066
115natural killer cell mediated cytotoxicity (GO:0042267)2.87013562
116natural killer cell mediated immunity (GO:0002228)2.87013562
117neutrophil chemotaxis (GO:0030593)2.86800577
118antigen processing and presentation via MHC class Ib (GO:0002475)2.85336632
119response to type I interferon (GO:0034340)2.85140142
120positive regulation of macrophage cytokine production (GO:0060907)2.85123307
121negative regulation of T-helper cell differentiation (GO:0045623)2.85089076
122negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.85089076
123positive regulation of B cell differentiation (GO:0045579)2.84399866
124T-helper 1 type immune response (GO:0042088)2.84185379
125antigen processing and presentation of endogenous antigen (GO:0019883)2.84147943
126positive regulation of lymphocyte migration (GO:2000403)2.84042088
127leukotriene metabolic process (GO:0006691)2.83806021
128cellular response to thyroid hormone stimulus (GO:0097067)2.82815241
129antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.81991706
130antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.81991706
131interferon-gamma-mediated signaling pathway (GO:0060333)2.81281701
132positive regulation of chemokine production (GO:0032722)2.81189393
133positive regulation of toll-like receptor signaling pathway (GO:0034123)2.80907206
134neutrophil migration (GO:1990266)2.78455430
135regulation of interferon-beta production (GO:0032648)2.77699459
136positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.77390917
137regulation of myeloid leukocyte mediated immunity (GO:0002886)2.76802461
138positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.72146351
139positive regulation of T cell migration (GO:2000406)2.69633123

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse7.39632211
2BP1_19119308_ChIP-ChIP_Hs578T_Human6.34499030
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.95382026
4IRF8_27001747_Chip-Seq_BMDM_Mouse5.11377868
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.76168642
6Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse4.10381202
7NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse4.08310978
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.35442850
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.28073332
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.17982642
11MYB_21317192_ChIP-Seq_ERMYB_Mouse3.03112876
12NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.93158369
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.75932505
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.46584814
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.46199881
16BRD4_27068464_Chip-Seq_AML-cells_Mouse2.42345157
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.42114386
18RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.40901524
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.34355934
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.34207728
21PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.32914569
22SPI1_23547873_ChIP-Seq_NB4_Human2.20584903
23SPI1_23127762_ChIP-Seq_K562_Human2.16613324
24SMAD_19615063_ChIP-ChIP_OVARY_Human2.07125198
25STAT4_19710469_ChIP-ChIP_TH1__Mouse1.95466732
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.92083229
27PU_27001747_Chip-Seq_BMDM_Mouse1.90152869
28VDR_24787735_ChIP-Seq_THP-1_Human1.88557668
29SCL_19346495_ChIP-Seq_HPC-7_Human1.84415208
30PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.82764837
31VDR_24763502_ChIP-Seq_THP-1_Human1.81075688
32CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.79340591
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.75892073
34VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.70056074
35CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.69325764
36RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.68752028
37MYC_22102868_ChIP-Seq_BL_Human1.63036678
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.62492926
39STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.59773817
40VDR_21846776_ChIP-Seq_THP-1_Human1.55399278
41RUNX_20019798_ChIP-Seq_JUKART_Human1.52866564
42CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.46111962
43NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.45878242
44CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.45307694
45MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.44648744
46MAF_26560356_Chip-Seq_TH1_Human1.39567979
47CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39539093
48GATA2_21666600_ChIP-Seq_HMVEC_Human1.38960438
49MYB_26560356_Chip-Seq_TH2_Human1.38365080
50E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.33305021
51FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.32037041
52PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.24701976
53GATA1_22025678_ChIP-Seq_K562_Human1.22303928
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.20911291
55PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20236062
56LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.19351450
57SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.17345317
58TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16156725
59CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.15819023
60SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12287900
61MYB_26560356_Chip-Seq_TH1_Human1.11133724
62VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.11059946
63STAT6_21828071_ChIP-Seq_BEAS2B_Human1.10112184
64GATA2_22383799_ChIP-Seq_G1ME_Mouse1.06121618
65GATA3_26560356_Chip-Seq_TH2_Human1.05792400
66STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.04884729
67GATA3_27048872_Chip-Seq_THYMUS_Human1.03607694
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.02753017
69ELK3_25401928_ChIP-Seq_HUVEC_Human1.02357779
70TCF7_22412390_ChIP-Seq_EML_Mouse1.01587720
71UTX_26944678_Chip-Seq_JUKART_Human1.01560785
72TFEB_21752829_ChIP-Seq_HELA_Human0.99823935
73GATA1_19941827_ChIP-Seq_MEL_Mouse0.97781649
74GATA1_19941826_ChIP-Seq_K562_Human0.97375057
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.97228289
76LXR_22158963_ChIP-Seq_LIVER_Mouse0.96406973
77ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.96032097
78KDM2B_26808549_Chip-Seq_SUP-B15_Human0.95936389
79EGR1_19032775_ChIP-ChIP_M12_Human0.95756041
80SPI1_20517297_ChIP-Seq_HL60_Human0.94633092
81KDM2B_26808549_Chip-Seq_JURKAT_Human0.93441207
82GATA2_19941826_ChIP-Seq_K562_Human0.92152046
83RXR_22158963_ChIP-Seq_LIVER_Mouse0.90707892
84GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88419029
85PU.1_20513432_ChIP-Seq_Bcells_Mouse0.87203760
86GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.87114622
87GATA1_19941827_ChIP-Seq_MEL86_Mouse0.86940731
88SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.86070544
89LXR_22292898_ChIP-Seq_THP-1_Human0.85347302
90GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84946056
91PPARA_22158963_ChIP-Seq_LIVER_Mouse0.82630746
92RARG_19884340_ChIP-ChIP_MEFs_Mouse0.81990622
93BCL6_27268052_Chip-Seq_Bcells_Human0.81913625
94IKZF1_21737484_ChIP-ChIP_HCT116_Human0.81600361
95TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.81084824
96GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78943960
97RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78800841
98CDX2_19796622_ChIP-Seq_MESCs_Mouse0.78797507
99NCOR1_26117541_ChIP-Seq_K562_Human0.78667547
100RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.78156070
101SMRT_27268052_Chip-Seq_Bcells_Human0.78031535
102BCOR_27268052_Chip-Seq_Bcells_Human0.77959738
103STAT1_20625510_ChIP-Seq_HELA_Human0.76844043
104KDM2B_26808549_Chip-Seq_DND41_Human0.75806992
105SOX2_20726797_ChIP-Seq_SW620_Human0.74948055
106CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.74420015
107MAF_26560356_Chip-Seq_TH2_Human0.73631948
108SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.73185147
109FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.71230630
110KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.70426662
111NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.69921555
112NRF2_20460467_ChIP-Seq_MEFs_Mouse0.69921555
113BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.68937323
114RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.67899664
115KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.66228350
116FOXO3_23340844_ChIP-Seq_DLD1_Human0.65956877
117CTCF_27219007_Chip-Seq_ERYTHROID_Human0.63862667

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology5.07441131
2MP0001835_abnormal_antigen_presentation3.86737780
3MP0003303_peritoneal_inflammation3.73332162
4MP0003436_decreased_susceptibility_to3.71326049
5MP0006082_CNS_inflammation3.38233164
6MP0002419_abnormal_innate_immunity3.26988735
7MP0003172_abnormal_lysosome_physiology3.21063251
8MP0009785_altered_susceptibility_to2.86595105
9MP0009840_abnormal_foam_cell2.85966285
10MP0002148_abnormal_hypersensitivity_rea2.85406535
11MP0005000_abnormal_immune_tolerance2.83884300
12MP0005025_abnormal_response_to2.64032610
13MP0003191_abnormal_cellular_cholesterol2.60058791
14MP0001790_abnormal_immune_system2.57626755
15MP0005387_immune_system_phenotype2.57626755
16MP0003724_increased_susceptibility_to2.53396555
17MP0002452_abnormal_antigen_presenting2.43829289
18MP0000604_amyloidosis2.32078086
19MP0004510_myositis2.31645053
20MP0001533_abnormal_skeleton_physiology2.28396021
21MP0005464_abnormal_platelet_physiology2.27991100
22MP0001800_abnormal_humoral_immune2.25641103
23MP0003690_abnormal_glial_cell2.19085464
24MP0002723_abnormal_immune_serum2.18499540
25MP0000685_abnormal_immune_system2.08532519
26MP0000569_abnormal_digit_pigmentation2.06217935
27MP0003075_altered_response_to2.02023962
28MP0001819_abnormal_immune_cell1.95031938
29MP0002420_abnormal_adaptive_immunity1.93426968
30MP0005671_abnormal_response_to1.88124325
31MP0003763_abnormal_thymus_physiology1.82639981
32MP0004947_skin_inflammation1.81454843
33MP0000343_altered_response_to1.76824691
34MP0001845_abnormal_inflammatory_respons1.76675958
35MP0002405_respiratory_system_inflammati1.72965708
36MP0003300_gastrointestinal_ulcer1.71687352
37MP0003448_altered_tumor_morphology1.70135449
38MP0008469_abnormal_protein_level1.69794149
39MP0003183_abnormal_peptide_metabolism1.63009031
40MP0005451_abnormal_body_composition1.58675321
41MP0009278_abnormal_bone_marrow1.57268271
42MP0005310_abnormal_salivary_gland1.56473966
43MP0002998_abnormal_bone_remodeling1.44759942
44MP0009764_decreased_sensitivity_to1.44024253
45MP0005166_decreased_susceptibility_to1.41260694
46MP0008438_abnormal_cutaneous_collagen1.39316654
47MP0002132_abnormal_respiratory_system1.38301771
48MP0005083_abnormal_biliary_tract1.36115867
49MP0000716_abnormal_immune_system1.35321312
50MP0003866_abnormal_defecation1.33630300
51MP0001853_heart_inflammation1.29580651
52MP0000689_abnormal_spleen_morphology1.29384124
53MP0010307_abnormal_tumor_latency1.28003766
54MP0010155_abnormal_intestine_physiology1.26565260
55MP0005167_abnormal_blood-brain_barrier1.24071499
56MP0009333_abnormal_splenocyte_physiolog1.24065852
57MP0003705_abnormal_hypodermis_morpholog1.20511407
58MP0002398_abnormal_bone_marrow1.17193779
59MP0000703_abnormal_thymus_morphology1.16228963
60MP0000465_gastrointestinal_hemorrhage1.15704711
61MP0003566_abnormal_cell_adhesion1.12019788
62MP0005257_abnormal_intraocular_pressure1.11643098
63MP0003656_abnormal_erythrocyte_physiolo1.11349554
64MP0000858_altered_metastatic_potential1.09035923
65MP0002429_abnormal_blood_cell1.08785010
66MP0001851_eye_inflammation1.08750160
67MP0002166_altered_tumor_susceptibility1.05973705
68MP0002006_tumorigenesis1.05139596
69MP0005390_skeleton_phenotype1.04389856
70MP0003828_pulmonary_edema1.04336087
71MP0004381_abnormal_hair_follicle1.04264099
72MP0002254_reproductive_system_inflammat1.04175478
73MP0005174_abnormal_tail_pigmentation1.03876691
74MP0002722_abnormal_immune_system1.02770441
75MP0002933_joint_inflammation1.01824221
76MP0002277_abnormal_respiratory_mucosa1.00147726
77MP0009763_increased_sensitivity_to0.99123909
78MP0002332_abnormal_exercise_endurance0.97934860
79MP0002396_abnormal_hematopoietic_system0.96181851
80MP0005397_hematopoietic_system_phenotyp0.93950638
81MP0001545_abnormal_hematopoietic_system0.93950638
82MP0004808_abnormal_hematopoietic_stem0.92346572
83MP0005164_abnormal_response_to0.91531873
84MP0000249_abnormal_blood_vessel0.91394314
85MP0001663_abnormal_digestive_system0.90661858
86MP0002138_abnormal_hepatobiliary_system0.88463023
87MP0005076_abnormal_cell_differentiation0.87640183
88MP0003195_calcinosis0.85957739
89MP0009765_abnormal_xenobiotic_induced0.85151567
90MP0003806_abnormal_nucleotide_metabolis0.84994606
91MP0002090_abnormal_vision0.80264071
92MP0005084_abnormal_gallbladder_morpholo0.79838313
93MP0004782_abnormal_surfactant_physiolog0.79663497
94MP0006054_spinal_hemorrhage0.75800739
95MP0003795_abnormal_bone_structure0.74978744
96MP0004858_abnormal_nervous_system0.73700130
97MP0000767_abnormal_smooth_muscle0.72219512
98MP0000609_abnormal_liver_physiology0.71635269
99MP0000015_abnormal_ear_pigmentation0.71176218
100MP0000920_abnormal_myelination0.71058671
101MP0003045_fibrosis0.70954493
102MP0001958_emphysema0.70723141
103MP0002136_abnormal_kidney_physiology0.68928690
104MP0008874_decreased_physiological_sensi0.68839647
105MP0003453_abnormal_keratinocyte_physiol0.67984247
106MP0008004_abnormal_stomach_pH0.67858177
107MP0004883_abnormal_blood_vessel0.67763766
108MP0008260_abnormal_autophagy0.67399172
109MP0000371_diluted_coat_color0.66574180
110MP0004130_abnormal_muscle_cell0.66531562
111MP0005023_abnormal_wound_healing0.65748911
112MP0003091_abnormal_cell_migration0.65304864
113MP0003221_abnormal_cardiomyocyte_apopto0.63300062
114MP0005197_abnormal_uvea_morphology0.61773798
115MP0001915_intracranial_hemorrhage0.61188716
116MP0003634_abnormal_glial_cell0.60518382
117MP0001873_stomach_inflammation0.58695999
118MP0000490_abnormal_crypts_of0.57554613
119MP0002877_abnormal_melanocyte_morpholog0.57525606
120MP0005075_abnormal_melanosome_morpholog0.57303011
121MP0003186_abnormal_redox_activity0.55132398
122MP0000598_abnormal_liver_morphology0.55054699
123MP0005381_digestive/alimentary_phenotyp0.53409078
124MP0005535_abnormal_body_temperature0.52463919
125MP0003252_abnormal_bile_duct0.50904152

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)7.76073353
2Recurrent abscess formation (HP:0002722)6.84837544
3Increased cerebral lipofuscin (HP:0011813)6.19147082
4Vacuolated lymphocytes (HP:0001922)6.04334641
5Recurrent bacterial skin infections (HP:0005406)5.84127921
6Eczematoid dermatitis (HP:0000976)5.66403631
7Recurrent gram-negative bacterial infections (HP:0005420)5.56586982
8Glomerulonephritis (HP:0000099)5.45686176
9Increased neuronal autofluorescent lipopigment (HP:0002074)5.36235414
10Dysostosis multiplex (HP:0000943)4.94255508
11Abnormality of macrophages (HP:0004311)4.88165218
12Abnormality of liposaccharide metabolism (HP:0010968)4.57792696
13Abnormality of glycosphingolipid metabolism (HP:0004343)4.57792696
14Abnormality of glycolipid metabolism (HP:0010969)4.57792696
15Disinhibition (HP:0000734)4.13746685
16Complement deficiency (HP:0004431)4.11838795
17Abnormality of complement system (HP:0005339)3.99607609
18Axonal loss (HP:0003447)3.97933079
19Prolonged bleeding time (HP:0003010)3.94058206
20Urinary glycosaminoglycan excretion (HP:0003541)3.87624039
21Mucopolysacchariduria (HP:0008155)3.87624039
22Abnormal delayed hypersensitivity skin test (HP:0002963)3.85351989
23Keratoconjunctivitis sicca (HP:0001097)3.73216630
24Gastrointestinal infarctions (HP:0005244)3.72293605
25Abnormality of mucopolysaccharide metabolism (HP:0011020)3.67083728
26Abnormality of polysaccharide metabolism (HP:0011012)3.67083728
27Abnormality of glycosaminoglycan metabolism (HP:0004371)3.67083728
28Mediastinal lymphadenopathy (HP:0100721)3.62911687
29Gingivitis (HP:0000230)3.58981054
30Encephalitis (HP:0002383)3.47804548
31Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.46213670
32Keratoconjunctivitis (HP:0001096)3.43796943
33Loss of speech (HP:0002371)3.36615136
34Recurrent skin infections (HP:0001581)3.35832225
35Epistaxis (HP:0000421)3.28361036
36Nephritis (HP:0000123)3.28272449
37Prostate neoplasm (HP:0100787)3.27809875
38Myositis (HP:0100614)3.27252258
39Chronic obstructive pulmonary disease (HP:0006510)3.24076948
40Obstructive lung disease (HP:0006536)3.24076948
41Recurrent cutaneous fungal infections (HP:0011370)3.22354855
42Chronic mucocutaneous candidiasis (HP:0002728)3.22354855
43Orchitis (HP:0100796)3.19355717
44Pustule (HP:0200039)3.16912759
45T lymphocytopenia (HP:0005403)3.14180928
46Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.09612701
47Chest pain (HP:0100749)3.09327538
48Agnosia (HP:0010524)3.05879178
49Hemoptysis (HP:0002105)3.05394726
50Myocardial infarction (HP:0001658)3.03436171
51Autoimmune thrombocytopenia (HP:0001973)3.02304426
52Increased IgE level (HP:0003212)3.01455091
53Abnormality of T cell number (HP:0011839)2.98520231
54Episodic fever (HP:0001954)2.97970267
55Purpura (HP:0000979)2.94505276
56Thick nail (HP:0001805)2.93135378
57Stomatitis (HP:0010280)2.91236949
58Optic neuritis (HP:0100653)2.83519663
59Retrobulbar optic neuritis (HP:0100654)2.83519663
60Upper motor neuron abnormality (HP:0002127)2.81438115
61Elevated erythrocyte sedimentation rate (HP:0003565)2.75190069
62Recurrent fungal infections (HP:0002841)2.75087085
63Periodontitis (HP:0000704)2.70733597
64Increased IgM level (HP:0003496)2.69323685
65Hematochezia (HP:0002573)2.68475863
66Hepatosplenomegaly (HP:0001433)2.66686777
67Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.65405610
68J-shaped sella turcica (HP:0002680)2.61954124
69Abnormality of T cells (HP:0002843)2.59180579
70Pathologic fracture (HP:0002756)2.55861155
71Pulmonary embolism (HP:0002204)2.55813563
72Gangrene (HP:0100758)2.54969869
73Anorexia (HP:0002039)2.54538413
74Peritonitis (HP:0002586)2.50289575
75Recurrent viral infections (HP:0004429)2.47893414
76Abnormal platelet volume (HP:0011876)2.47605437
77Increased serum ferritin (HP:0003281)2.45278137
78Gastrointestinal inflammation (HP:0004386)2.44989829
79Mutism (HP:0002300)2.42312228
80Granulocytopenia (HP:0001913)2.42184977
81Basal ganglia calcification (HP:0002135)2.41866043
82Abnormality of the lumbar spine (HP:0100712)2.41313280
83Asymmetric septal hypertrophy (HP:0001670)2.40850576
84Cellulitis (HP:0100658)2.39031870
85Thoracic kyphosis (HP:0002942)2.36890229
86Urticaria (HP:0001025)2.36512662
87Panhypogammaglobulinemia (HP:0003139)2.34070021
88Abnormality of the vasculature of the conjunctiva (HP:0008054)2.34014734
89Interstitial pulmonary disease (HP:0006530)2.31927244
90Autoimmune hemolytic anemia (HP:0001890)2.29335042
91Osteolytic defects of the phalanges of the hand (HP:0009771)2.25887005
92Osteolytic defects of the hand bones (HP:0009699)2.25887005
93Vertigo (HP:0002321)2.25402346
94Abnormality of the pleura (HP:0002103)2.25370445
95Abnormality of iron homeostasis (HP:0011031)2.25223990
96Neuronal loss in central nervous system (HP:0002529)2.22751740
97Apathy (HP:0000741)2.22390470
98Diminished motivation (HP:0000745)2.22158690
99Peripheral demyelination (HP:0011096)2.22056589
100Spontaneous hematomas (HP:0007420)2.20152418
101Hypergammaglobulinemia (HP:0010702)2.20072386
102Abnormality of T cell physiology (HP:0011840)2.19552257
103Eosinophilia (HP:0001880)2.19311507
104Hypochromic microcytic anemia (HP:0004840)2.19305169
105Osteomyelitis (HP:0002754)2.18187794
106Vasculitis (HP:0002633)2.15690205
107Colitis (HP:0002583)2.14664452
108Inappropriate behavior (HP:0000719)2.12694537
109Neoplasm of the tracheobronchial system (HP:0100552)2.12588177
110Conjunctival telangiectasia (HP:0000524)2.12578548
111Hypochromic anemia (HP:0001931)2.12421688
112Bone pain (HP:0002653)2.12394227
113Pulmonary infiltrates (HP:0002113)2.11818378
114Slow saccadic eye movements (HP:0000514)2.11709445
115Alveolar cell carcinoma (HP:0006519)2.11237951
116Arterial thrombosis (HP:0004420)2.11076569
117Polyneuropathy (HP:0001271)2.10534625
118Joint hemorrhage (HP:0005261)2.10253741
119Tetraparesis (HP:0002273)2.10178330
120Progressive visual loss (HP:0000529)2.09583189
121Sepsis (HP:0100806)2.06650702
122Lymphopenia (HP:0001888)2.03063100
123Glomerulopathy (HP:0100820)2.02775122
124Retinal atrophy (HP:0001105)2.02698673
125Leukocytosis (HP:0001974)2.02662586
126Abnormality of the endocardium (HP:0004306)1.98797850
127Joint swelling (HP:0001386)1.96794611
128Spondylolisthesis (HP:0003302)1.96661881
129Recurrent pneumonia (HP:0006532)1.96507784
130Global brain atrophy (HP:0002283)1.96147162
131Menorrhagia (HP:0000132)1.95199165
132Petechiae (HP:0000967)1.94905376
133Vertebral compression fractures (HP:0002953)1.94614398
134Amaurosis fugax (HP:0100576)1.93885903
135Neurofibrillary tangles (HP:0002185)1.93677590
136Personality changes (HP:0000751)1.93546113
137Acne (HP:0001061)1.92860571
138Progressive neurologic deterioration (HP:0002344)1.92191828
139Deformed sella turcica (HP:0002681)1.90883425
140Chronic otitis media (HP:0000389)1.90522415
141Abnormality of cells of the lymphoid lineage (HP:0012140)1.90288136
142Meningitis (HP:0001287)1.89804273
143Inflammation of the large intestine (HP:0002037)1.89450782
144Amyloidosis (HP:0011034)1.88967826
145Microcytic anemia (HP:0001935)1.88206492
146Keratitis (HP:0000491)1.87949422
147Increased mean platelet volume (HP:0011877)1.86674224
148Arthralgia (HP:0002829)1.85989735
149Gingival bleeding (HP:0000225)1.83100760
150Abnormality of the prostate (HP:0008775)1.76596591
151Supranuclear gaze palsy (HP:0000605)1.76025190
152Frequent falls (HP:0002359)1.75949355
153Increased CSF protein (HP:0002922)1.74394743
154Abnormality of the thoracic spine (HP:0100711)1.74333437

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BLK4.94349671
2RIPK43.55818576
3TYK23.42240249
4TBK13.32263545
5IRAK42.87980634
6KIT2.87761037
7MAP3K142.82520329
8TGFBR22.74736464
9IRAK32.70417686
10ERN12.51760056
11MAP4K12.44789444
12PRPF4B2.29600058
13CSF1R2.27822125
14IKBKE2.15918890
15FGR2.14177103
16FES2.06103452
17JAK11.94783186
18TNK21.79975696
19CAMK1D1.78935593
20MAP3K131.75556154
21CSK1.74231367
22TAOK11.74143017
23IKBKB1.70071208
24PBK1.67262427
25TAOK31.66415918
26NEK91.55166343
27HCK1.52328545
28ZAP701.51886610
29GRK71.50625526
30TRIB31.50195137
31JAK31.48086413
32PKN21.47865606
33EPHB11.46352140
34TXK1.45277491
35SYK1.39170964
36STK101.35314498
37TAOK21.30828167
38MAP2K31.30239253
39LYN1.28910225
40IRAK11.28226868
41RIPK11.27381267
42JAK21.23257754
43CAMK1G1.21776710
44MATK1.20294092
45LCK1.19402237
46IRAK21.14111581
47TTN1.13656713
48SCYL21.13264929
49SIK31.12065884
50CAMKK21.07371757
51PTK61.05309446
52BTK1.04764137
53MST1R1.02593688
54MAP3K50.99621558
55EGFR0.89891127
56NME20.89548067
57MAP3K30.84977561
58CAMKK10.81358750
59DAPK20.81246754
60MOS0.81152330
61RPS6KA40.80386801
62CHUK0.79450556
63MARK20.79346250
64BMX0.78029140
65PRKCD0.72104453
66CLK10.71418222
67CDC42BPA0.71239567
68PAK40.71085859
69LRRK20.68641496
70PIM20.68178606
71ITK0.67870285
72GRK60.66716467
73MARK30.65853182
74SIK20.65120769
75TEC0.64091396
76FGFR40.62900586
77MAP3K20.62437346
78PTK2B0.62056759
79HIPK20.62005982
80FYN0.61018351
81ABL20.60404047
82MAP3K60.60255387
83ABL10.59566667
84EPHA30.57339544
85SGK30.53899748
86TESK20.52569702
87MAPK70.51152585
88MAPK120.49932912
89FGFR30.49838640
90PIM10.48201412
91TRPM70.47527351
92IGF1R0.46751708
93PRKD20.45264284
94KSR20.44729747
95PDPK10.42753887
96MAP3K110.42009191
97NLK0.41893419
98PIK3CG0.41557073
99PRKCQ0.41527281
100STK240.41463430
101CDK60.41268673
102BMPR20.40965806
103ARAF0.40828452
104STK40.40525926
105PDK10.40405806
106MAPKAPK20.39091322
107SGK20.38243096
108CDK190.37851838
109MAP2K40.37373512
110EIF2AK20.36162587
111PRKCH0.34598124
112RPS6KA60.34383288
113MAP3K70.34080730
114DYRK1B0.33957057
115STK110.32313429
116KSR10.31180586
117ADRBK20.30738263
118MAP2K60.30573281
119DAPK30.30331476
120RAF10.29250373
121ACVR1B0.28425942
122YES10.28227517
123RET0.27474830
124DYRK30.27360097
125RPS6KA20.27148632
126PKN10.26495634
127SRC0.26494582
128RPS6KC10.26161686
129RPS6KL10.26161686
130GSK3A0.24892941
131MAP3K10.24581204
132PLK20.24334355
133MAPK40.23708367
134MAP3K100.22659721
135INSR0.22313711

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051505.27044505
2Glycosaminoglycan degradation_Homo sapiens_hsa005313.52908938
3Lysosome_Homo sapiens_hsa041423.36365671
4Other glycan degradation_Homo sapiens_hsa005113.19088812
5Leishmaniasis_Homo sapiens_hsa051403.18183556
6Pertussis_Homo sapiens_hsa051332.70350301
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.60310016
8Osteoclast differentiation_Homo sapiens_hsa043802.55289595
9Tuberculosis_Homo sapiens_hsa051522.33033045
10Legionellosis_Homo sapiens_hsa051342.21469054
11Phagosome_Homo sapiens_hsa041452.16302315
12Malaria_Homo sapiens_hsa051442.05525075
13Complement and coagulation cascades_Homo sapiens_hsa046101.99870945
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.84590664
15Rheumatoid arthritis_Homo sapiens_hsa053231.83456135
16B cell receptor signaling pathway_Homo sapiens_hsa046621.79719575
17Measles_Homo sapiens_hsa051621.63522883
18Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.62282387
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.61133772
20Salmonella infection_Homo sapiens_hsa051321.60249387
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.57515011
22Antigen processing and presentation_Homo sapiens_hsa046121.56853894
23Graft-versus-host disease_Homo sapiens_hsa053321.56186392
24Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.45017863
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.44771707
26Influenza A_Homo sapiens_hsa051641.43719823
27Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.42871109
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.39443016
29Toxoplasmosis_Homo sapiens_hsa051451.37819324
30Caffeine metabolism_Homo sapiens_hsa002321.34879231
31Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.33793859
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.31515503
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.30522570
34Prion diseases_Homo sapiens_hsa050201.30114693
35TNF signaling pathway_Homo sapiens_hsa046681.25139564
36Chemokine signaling pathway_Homo sapiens_hsa040621.22964434
37Hematopoietic cell lineage_Homo sapiens_hsa046401.19503108
38Apoptosis_Homo sapiens_hsa042101.14887640
39Shigellosis_Homo sapiens_hsa051311.14741780
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.14475589
41Intestinal immune network for IgA production_Homo sapiens_hsa046721.10113381
42Allograft rejection_Homo sapiens_hsa053301.07962543
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.04847438
44Amoebiasis_Homo sapiens_hsa051461.04114858
45Asthma_Homo sapiens_hsa053100.99973485
46Non-small cell lung cancer_Homo sapiens_hsa052230.98423633
47Herpes simplex infection_Homo sapiens_hsa051680.96108401
48Leukocyte transendothelial migration_Homo sapiens_hsa046700.93880308
49Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.89417242
50Hepatitis C_Homo sapiens_hsa051600.89213537
51Hepatitis B_Homo sapiens_hsa051610.88066126
52Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.87695095
53Jak-STAT signaling pathway_Homo sapiens_hsa046300.86854705
54African trypanosomiasis_Homo sapiens_hsa051430.80090374
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80046507
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74926765
57Viral myocarditis_Homo sapiens_hsa054160.73769335
58Sphingolipid metabolism_Homo sapiens_hsa006000.73252766
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72581393
60AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71522687
61Dorso-ventral axis formation_Homo sapiens_hsa043200.67028655
62Pancreatic cancer_Homo sapiens_hsa052120.66179447
63Platelet activation_Homo sapiens_hsa046110.65981891
64Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62431115
65Endocytosis_Homo sapiens_hsa041440.61712531
66Type I diabetes mellitus_Homo sapiens_hsa049400.61689581
67Chronic myeloid leukemia_Homo sapiens_hsa052200.59458569
68Collecting duct acid secretion_Homo sapiens_hsa049660.59298434
69FoxO signaling pathway_Homo sapiens_hsa040680.59287601
70Mineral absorption_Homo sapiens_hsa049780.57616486
71Neurotrophin signaling pathway_Homo sapiens_hsa047220.53295617
72Sphingolipid signaling pathway_Homo sapiens_hsa040710.51907609
73GnRH signaling pathway_Homo sapiens_hsa049120.51312205
74Acute myeloid leukemia_Homo sapiens_hsa052210.50526498
75T cell receptor signaling pathway_Homo sapiens_hsa046600.50357724
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49625983
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48942012
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48701644
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.48274072
80mTOR signaling pathway_Homo sapiens_hsa041500.47118644
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.46433577
82MAPK signaling pathway_Homo sapiens_hsa040100.45988980
83HTLV-I infection_Homo sapiens_hsa051660.45459854
84Choline metabolism in cancer_Homo sapiens_hsa052310.44136310
85Endometrial cancer_Homo sapiens_hsa052130.43587888
86HIF-1 signaling pathway_Homo sapiens_hsa040660.42025515
87Type II diabetes mellitus_Homo sapiens_hsa049300.40874838
88Renin-angiotensin system_Homo sapiens_hsa046140.40749170
89Bladder cancer_Homo sapiens_hsa052190.39702765
90VEGF signaling pathway_Homo sapiens_hsa043700.39194270
91ABC transporters_Homo sapiens_hsa020100.37802499
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.35496083
93Proteoglycans in cancer_Homo sapiens_hsa052050.34983342
94Autoimmune thyroid disease_Homo sapiens_hsa053200.34912318
95Arachidonic acid metabolism_Homo sapiens_hsa005900.31445501
96Prolactin signaling pathway_Homo sapiens_hsa049170.31342817
97Rap1 signaling pathway_Homo sapiens_hsa040150.30942088
98Regulation of autophagy_Homo sapiens_hsa041400.30678910
99Inositol phosphate metabolism_Homo sapiens_hsa005620.29137159
100Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28965190
101ErbB signaling pathway_Homo sapiens_hsa040120.27559721
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.27212074
103Notch signaling pathway_Homo sapiens_hsa043300.26678036
104Small cell lung cancer_Homo sapiens_hsa052220.25162352
105Renal cell carcinoma_Homo sapiens_hsa052110.23837567
106Epstein-Barr virus infection_Homo sapiens_hsa051690.23741206
107Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.23629356
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23257164
109Primary immunodeficiency_Homo sapiens_hsa053400.22378552
110Insulin resistance_Homo sapiens_hsa049310.22130857
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.20057766
112Steroid biosynthesis_Homo sapiens_hsa001000.19380755
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.19330999
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18239361
115Viral carcinogenesis_Homo sapiens_hsa052030.17982604
116Histidine metabolism_Homo sapiens_hsa003400.17100754
117Galactose metabolism_Homo sapiens_hsa000520.16743307
118Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.15846371
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.14281456
120Phospholipase D signaling pathway_Homo sapiens_hsa040720.14220518

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