ADGRG3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cell killing (GO:0031342)6.32146336
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.32146336
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.28199762
4ribosomal small subunit assembly (GO:0000028)6.27748779
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.94833173
6positive regulation by organism of defense response of other organism involved in symbiotic interact5.94833173
7modulation by symbiont of host immune response (GO:0052553)5.94833173
8positive regulation by symbiont of host defense response (GO:0052509)5.94833173
9modulation by symbiont of host defense response (GO:0052031)5.94833173
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.94833173
11leukocyte migration involved in inflammatory response (GO:0002523)5.82102495
12neutrophil activation involved in immune response (GO:0002283)5.71697266
13detection of other organism (GO:0098543)5.70128116
14detection of bacterium (GO:0016045)5.43605683
15positive regulation of gamma-delta T cell activation (GO:0046645)5.34141401
16response to peptidoglycan (GO:0032494)5.31692443
17negative regulation of phagocytosis (GO:0050765)5.24110638
18DNA deamination (GO:0045006)5.23886641
19cellular extravasation (GO:0045123)5.13479873
20macrophage activation involved in immune response (GO:0002281)4.90691174
21detection of external biotic stimulus (GO:0098581)4.88013927
22neutrophil activation (GO:0042119)4.79259992
23DNA strand elongation involved in DNA replication (GO:0006271)4.78204869
24detection of molecule of bacterial origin (GO:0032490)4.74352553
25telomere maintenance via semi-conservative replication (GO:0032201)4.73858349
26regulation of B cell receptor signaling pathway (GO:0050855)4.71694145
27antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.66440283
28antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.66440283
29DNA strand elongation (GO:0022616)4.61043172
30response to host immune response (GO:0052572)4.59937031
31response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.59937031
32positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.51490725
33negative regulation of lymphocyte mediated immunity (GO:0002707)4.45165136
34negative regulation of interleukin-12 production (GO:0032695)4.35805589
35disruption of cells of other organism involved in symbiotic interaction (GO:0051818)4.34793647
36killing of cells in other organism involved in symbiotic interaction (GO:0051883)4.34793647
37response to interleukin-15 (GO:0070672)4.32986020
38DNA unwinding involved in DNA replication (GO:0006268)4.31363675
39detection of biotic stimulus (GO:0009595)4.27464725
40granulocyte activation (GO:0036230)4.27419919
41negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)4.25757913
42regulation of interferon-beta biosynthetic process (GO:0045357)4.25610951
43response to host defenses (GO:0052200)4.21787325
44response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.21787325
45response to host (GO:0075136)4.21787325
46viral transcription (GO:0019083)4.17916374
47production of molecular mediator involved in inflammatory response (GO:0002532)4.13741982
48neutrophil mediated immunity (GO:0002446)4.12641478
49telomere maintenance via recombination (GO:0000722)4.03055325
50DNA replication initiation (GO:0006270)4.01847806
51translational termination (GO:0006415)4.00238392
52regulation of gamma-delta T cell activation (GO:0046643)3.90730626
53regulation of mast cell degranulation (GO:0043304)3.89257430
54cellular response to interleukin-15 (GO:0071350)3.89043460
55negative regulation of leukocyte mediated immunity (GO:0002704)3.87493559
56SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.86980543
57microglial cell activation (GO:0001774)3.85847859
58positive regulation of B cell differentiation (GO:0045579)3.78293245
59cotranslational protein targeting to membrane (GO:0006613)3.77991717
60protein targeting to ER (GO:0045047)3.74551602
61defense response to fungus (GO:0050832)3.74381539
62myeloid cell activation involved in immune response (GO:0002275)3.74207970
63macrophage activation (GO:0042116)3.73396984
64antigen processing and presentation of endogenous antigen (GO:0019883)3.70156826
65mitotic recombination (GO:0006312)3.67027245
66angiogenesis involved in wound healing (GO:0060055)3.65177066
67regulation of myeloid leukocyte mediated immunity (GO:0002886)3.63559333
68translational elongation (GO:0006414)3.59541813
69regulation of mast cell activation involved in immune response (GO:0033006)3.59535213
70maturation of SSU-rRNA (GO:0030490)3.59216063
71modulation of growth of symbiont involved in interaction with host (GO:0044144)3.57439219
72regulation of growth of symbiont in host (GO:0044126)3.57439219
73negative regulation of growth of symbiont in host (GO:0044130)3.57439219
74negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.57439219
75germinal center formation (GO:0002467)3.57332213
76establishment of protein localization to endoplasmic reticulum (GO:0072599)3.56836662
77negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.56560408
78negative regulation of T-helper cell differentiation (GO:0045623)3.56560408
79definitive hemopoiesis (GO:0060216)3.55589714
80protein localization to endoplasmic reticulum (GO:0070972)3.55352876
81response to fungus (GO:0009620)3.54669309
82ribosomal small subunit biogenesis (GO:0042274)3.54509630
83antigen processing and presentation via MHC class Ib (GO:0002475)3.53967525
84type I interferon signaling pathway (GO:0060337)3.52257017
85cellular response to type I interferon (GO:0071357)3.52257017
86response to type I interferon (GO:0034340)3.49532998
87telomere maintenance via telomere lengthening (GO:0010833)3.48423832
88leukocyte degranulation (GO:0043299)3.47878875
89regulation of T-helper 2 cell differentiation (GO:0045628)3.45100426
90IMP metabolic process (GO:0046040)3.44107008
91platelet dense granule organization (GO:0060155)3.43972283
92regulation of leukocyte degranulation (GO:0043300)3.41378502
93negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.40751122
94regulation of gamma-delta T cell differentiation (GO:0045586)3.39847917
95negative regulation of T cell mediated immunity (GO:0002710)3.39614572
96regulation of mast cell activation (GO:0033003)3.36628526
97lymphoid progenitor cell differentiation (GO:0002320)3.35394164
98DNA replication checkpoint (GO:0000076)3.35379631
99positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.32638541
100neutrophil chemotaxis (GO:0030593)3.32462526
101positive regulation of mast cell activation (GO:0033005)3.31621660
102Arp2/3 complex-mediated actin nucleation (GO:0034314)3.30744614
103mast cell activation (GO:0045576)3.30482200
104nucleotide-excision repair, DNA gap filling (GO:0006297)3.29178374
105response to muramyl dipeptide (GO:0032495)3.28661830
106IMP biosynthetic process (GO:0006188)3.27216663
107negative regulation of interleukin-6 production (GO:0032715)3.26002710
108deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.24621606
109neutrophil migration (GO:1990266)3.24034359
110killing of cells of other organism (GO:0031640)3.21582035
111disruption of cells of other organism (GO:0044364)3.21582035
112myeloid leukocyte mediated immunity (GO:0002444)3.21217245
113pentose-phosphate shunt (GO:0006098)3.21105138
114B cell receptor signaling pathway (GO:0050853)3.19644615
115nucleobase biosynthetic process (GO:0046112)3.14302077
116regulation of tolerance induction (GO:0002643)3.14106696
117nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.13640114
118positive regulation of toll-like receptor signaling pathway (GO:0034123)3.13424085
119B cell mediated immunity (GO:0019724)3.09880080
120regulation of T cell tolerance induction (GO:0002664)3.08148323
121regulation of regulated secretory pathway (GO:1903305)3.07802524
122viral life cycle (GO:0019058)3.07452085
123positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.06153943
124negative regulation of alpha-beta T cell activation (GO:0046636)3.05037459
125cellular protein complex disassembly (GO:0043624)3.04045688
126regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.03364517
127necroptotic process (GO:0070266)3.02792806
128lipopolysaccharide-mediated signaling pathway (GO:0031663)3.02414454
129mast cell degranulation (GO:0043303)3.00813702
130mast cell activation involved in immune response (GO:0002279)3.00813702
131megakaryocyte development (GO:0035855)3.00632699
132negative regulation of type 2 immune response (GO:0002829)2.99819753
133dendritic cell migration (GO:0036336)2.98974746
134positive regulation of T cell mediated cytotoxicity (GO:0001916)2.98049712
135regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.97958918
136negative regulation of innate immune response (GO:0045824)2.97810825
137interferon-gamma-mediated signaling pathway (GO:0060333)2.95549017
138positive regulation of mast cell degranulation (GO:0043306)2.95366292
139positive regulation of mast cell activation involved in immune response (GO:0033008)2.95366292
140translational initiation (GO:0006413)2.95349071
141protein localization to kinetochore (GO:0034501)2.94933601
142regulation of B cell differentiation (GO:0045577)2.94617601
143negative regulation of cytokine production involved in immune response (GO:0002719)2.94468152
144regulation of T cell mediated cytotoxicity (GO:0001914)2.94284710
145myeloid leukocyte activation (GO:0002274)2.94111691
146dendritic cell chemotaxis (GO:0002407)2.93223450
147negative regulation of erythrocyte differentiation (GO:0045647)2.92570154
148regulation of dendritic cell antigen processing and presentation (GO:0002604)2.89129329
149respiratory burst (GO:0045730)2.87564777
150response to interferon-beta (GO:0035456)2.86164984
151fucose catabolic process (GO:0019317)2.85136558
152L-fucose metabolic process (GO:0042354)2.85136558
153L-fucose catabolic process (GO:0042355)2.85136558
154NADPH regeneration (GO:0006740)2.84438249
155CENP-A containing nucleosome assembly (GO:0034080)2.82335042
156translesion synthesis (GO:0019985)2.80101796
157response to protozoan (GO:0001562)2.79857257
158intra-S DNA damage checkpoint (GO:0031573)2.79699546
159protein complex disassembly (GO:0043241)2.77683206
160defense response to protozoan (GO:0042832)2.77100117
161DNA topological change (GO:0006265)2.76918897
162macrophage differentiation (GO:0030225)2.75364366
163purine nucleobase biosynthetic process (GO:0009113)2.73127233
164pentose metabolic process (GO:0019321)2.71879635
165telomere maintenance (GO:0000723)2.70758643
166telomere organization (GO:0032200)2.69095414
167cellular response to zinc ion (GO:0071294)2.68843662
168negative regulation of RNA splicing (GO:0033119)2.68658985
169secretory granule organization (GO:0033363)2.67812659
170nuclear-transcribed mRNA catabolic process (GO:0000956)2.64920819
171pseudouridine synthesis (GO:0001522)2.64212935
172chromatin remodeling at centromere (GO:0031055)2.62822887
173viral mRNA export from host cell nucleus (GO:0046784)2.60168969
174cellular response to interferon-beta (GO:0035458)2.59820384
175macromolecular complex disassembly (GO:0032984)2.59077252
176T cell homeostasis (GO:0043029)2.57658385
177purine-containing compound salvage (GO:0043101)2.56148884
178mRNA catabolic process (GO:0006402)2.52826558
179programmed necrotic cell death (GO:0097300)2.52801383
180leukocyte aggregation (GO:0070486)2.52689027
181protein localization to chromosome, centromeric region (GO:0071459)2.50365973
182immunoglobulin mediated immune response (GO:0016064)2.50195179
183regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.49792788
184DNA replication-independent nucleosome assembly (GO:0006336)2.49030299
185DNA replication-independent nucleosome organization (GO:0034724)2.49030299

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.12875861
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.41340088
3SCL_19346495_ChIP-Seq_HPC-7_Human3.24580379
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.07911835
5ELF1_17652178_ChIP-ChIP_JURKAT_Human2.91170123
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.90149740
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.88215943
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.87806385
9SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.79952891
10MYB_21317192_ChIP-Seq_ERMYB_Mouse2.76905246
11VDR_21846776_ChIP-Seq_THP-1_Human2.64370363
12RUNX_20019798_ChIP-Seq_JUKART_Human2.60254568
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.48520781
14RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.48352154
15TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.37586379
16MYC_22102868_ChIP-Seq_BL_Human2.33516430
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.33288806
18FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.33022067
19IRF8_22096565_ChIP-ChIP_GC-B_Human2.30028253
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.27741529
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.17845798
22NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.17485504
23IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.17047004
24EST1_17652178_ChIP-ChIP_JURKAT_Human2.14063261
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.13392486
26MYC_18358816_ChIP-ChIP_MESCs_Mouse2.11291240
27SPI1_23547873_ChIP-Seq_NB4_Human2.10014693
28SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.09887719
29BP1_19119308_ChIP-ChIP_Hs578T_Human2.07429447
30VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.04687537
31KDM2B_26808549_Chip-Seq_SUP-B15_Human2.00146700
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.99553721
33GABP_17652178_ChIP-ChIP_JURKAT_Human1.97231802
34SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.96443944
35HOXB4_20404135_ChIP-ChIP_EML_Mouse1.95621286
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.94070927
37JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.92018930
38GATA1_22025678_ChIP-Seq_K562_Human1.90081594
39ERG_20887958_ChIP-Seq_HPC-7_Mouse1.89067357
40CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.88639324
41VDR_24763502_ChIP-Seq_THP-1_Human1.86716023
42MYC_19030024_ChIP-ChIP_MESCs_Mouse1.85330484
43VDR_23849224_ChIP-Seq_CD4+_Human1.84845717
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.82008568
45FOXP3_21729870_ChIP-Seq_TREG_Human1.80774734
46IRF8_21731497_ChIP-ChIP_J774_Mouse1.78838986
47KDM2B_26808549_Chip-Seq_DND41_Human1.77531614
48Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.76244131
49VDR_24787735_ChIP-Seq_THP-1_Human1.74497867
50MYC_19079543_ChIP-ChIP_MESCs_Mouse1.73932345
51CIITA_25753668_ChIP-Seq_RAJI_Human1.73767747
52RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.72974214
53BRD4_27068464_Chip-Seq_AML-cells_Mouse1.72678630
54STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.72392691
55RUNX1_22412390_ChIP-Seq_EML_Mouse1.68399486
56STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.67939582
57KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.66384686
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.65586961
59NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.65114622
60LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.64066418
61XRN2_22483619_ChIP-Seq_HELA_Human1.63295840
62THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.63102810
63CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.62920234
64GATA3_27048872_Chip-Seq_THYMUS_Human1.62557516
65GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.61493109
66MYB_26560356_Chip-Seq_TH2_Human1.60907011
67FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.57048830
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.56243163
69STAT4_19710469_ChIP-ChIP_TH1__Mouse1.56157650
70GATA1_19941827_ChIP-Seq_MEL_Mouse1.56064222
71CREB1_15753290_ChIP-ChIP_HEK293T_Human1.55230586
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.53255230
73GATA1_22383799_ChIP-Seq_G1ME_Mouse1.53082402
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.51760082
75SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.50725760
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.50588222
77NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.49594651
78KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.49561648
79LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.48784059
80MAF_26560356_Chip-Seq_TH1_Human1.45648278
81CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.44194086
82NOTCH1_21737748_ChIP-Seq_TLL_Human1.44152165
83MYB_26560356_Chip-Seq_TH1_Human1.42528054
84PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.42413145
85MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.40925698
86UTX_26944678_Chip-Seq_JUKART_Human1.38762735
87NELFA_20434984_ChIP-Seq_ESCs_Mouse1.38068335
88ELK3_25401928_ChIP-Seq_HUVEC_Human1.37046028
89GABP_19822575_ChIP-Seq_HepG2_Human1.34732270
90PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33406471
91DCP1A_22483619_ChIP-Seq_HELA_Human1.32184912
92SRF_21415370_ChIP-Seq_HL-1_Mouse1.30824081
93GATA3_26560356_Chip-Seq_TH2_Human1.30738646
94GATA2_22383799_ChIP-Seq_G1ME_Mouse1.30523324
95HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29546029
96CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.29485623
97E2F1_18555785_ChIP-Seq_MESCs_Mouse1.29021682
98LXR_22292898_ChIP-Seq_THP-1_Human1.28843603
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.27242653
100SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27086526
101GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24560435
102TTF2_22483619_ChIP-Seq_HELA_Human1.23997688
103TCF7_22412390_ChIP-Seq_EML_Mouse1.23842134
104AR_21909140_ChIP-Seq_LNCAP_Human1.23305104
105PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23024173
106IRF8_27001747_Chip-Seq_BMDM_Mouse1.22869297
107ELK1_19687146_ChIP-ChIP_HELA_Human1.20404941
108CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.20113515
109IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.20046868
110GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19606495
111KDM2B_26808549_Chip-Seq_JURKAT_Human1.18720431
112CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.16929344
113GATA1_19941826_ChIP-Seq_K562_Human1.16510104
114BCL6_27268052_Chip-Seq_Bcells_Human1.15447146
115VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.15182087
116SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14739453
117GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.13863730
118ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12747985
119PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12626531
120THAP11_20581084_ChIP-Seq_MESCs_Mouse1.10988765
121BCOR_27268052_Chip-Seq_Bcells_Human1.10650475
122MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.10290065
123GATA2_21666600_ChIP-Seq_HMVEC_Human1.09227344
124IKZF1_21737484_ChIP-ChIP_HCT116_Human1.09065808
125YY1_21170310_ChIP-Seq_MESCs_Mouse1.08741334
126E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04721362
127MYCN_18555785_ChIP-Seq_MESCs_Mouse1.03735972
128FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.00417002
129KDM5A_27292631_Chip-Seq_BREAST_Human0.97234000
130SPI1_23127762_ChIP-Seq_K562_Human0.96932820
131STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.96410378
132TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96397225
133E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.94940188
134RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94934167
135GATA2_19941826_ChIP-Seq_K562_Human0.94827608
136MAF_26560356_Chip-Seq_TH2_Human0.94321217
137CTCF_27219007_Chip-Seq_ERYTHROID_Human0.94048329
138SPI1_20517297_ChIP-Seq_HL60_Human0.92187061
139PU.1_20513432_ChIP-Seq_Bcells_Mouse0.91847909
140NCOR1_26117541_ChIP-Seq_K562_Human0.91667354
141RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.91356360
142CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.90190322
143FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89656528
144PU_27001747_Chip-Seq_BMDM_Mouse0.89443671
145TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87612992
146STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86576608
147RACK7_27058665_Chip-Seq_MCF-7_Human0.82426613
148NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.82286775
149SA1_27219007_Chip-Seq_ERYTHROID_Human0.80737140

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system5.25553602
2MP0001835_abnormal_antigen_presentation3.02889114
3MP0010094_abnormal_chromosome_stability3.00167590
4MP0003693_abnormal_embryo_hatching2.92591367
5MP0001545_abnormal_hematopoietic_system2.82061997
6MP0005397_hematopoietic_system_phenotyp2.82061997
7MP0004808_abnormal_hematopoietic_stem2.76671808
8MP0008057_abnormal_DNA_replication2.74453518
9MP0009785_altered_susceptibility_to2.71936854
10MP0005464_abnormal_platelet_physiology2.53394124
11MP0005174_abnormal_tail_pigmentation2.50789417
12MP0000465_gastrointestinal_hemorrhage2.43427620
13MP0003436_decreased_susceptibility_to2.40584357
14MP0006082_CNS_inflammation2.38757092
15MP0002419_abnormal_innate_immunity2.34636195
16MP0003724_increased_susceptibility_to2.34044992
17MP0005025_abnormal_response_to2.31593941
18MP0002132_abnormal_respiratory_system2.24397955
19MP0002166_altered_tumor_susceptibility2.24216670
20MP0002398_abnormal_bone_marrow2.22174444
21MP0003111_abnormal_nucleus_morphology2.18795769
22MP0000490_abnormal_crypts_of2.14848993
23MP0005075_abnormal_melanosome_morpholog2.14744116
24MP0008007_abnormal_cellular_replicative2.13134269
25MP0003077_abnormal_cell_cycle2.11507545
26MP0003763_abnormal_thymus_physiology2.11234278
27MP0008260_abnormal_autophagy2.08560998
28MP0002420_abnormal_adaptive_immunity2.07308471
29MP0001819_abnormal_immune_cell2.03181461
30MP0000685_abnormal_immune_system1.99389301
31MP0006054_spinal_hemorrhage1.98969032
32MP0005671_abnormal_response_to1.95182339
33MP0001800_abnormal_humoral_immune1.94393798
34MP0002148_abnormal_hypersensitivity_rea1.91794868
35MP0005000_abnormal_immune_tolerance1.90302224
36MP0002452_abnormal_antigen_presenting1.89941520
37MP0000689_abnormal_spleen_morphology1.88618818
38MP0002723_abnormal_immune_serum1.88350816
39MP0008058_abnormal_DNA_repair1.86844565
40MP0004957_abnormal_blastocyst_morpholog1.86752824
41MP0001853_heart_inflammation1.86544958
42MP0000716_abnormal_immune_system1.85824894
43MP0002277_abnormal_respiratory_mucosa1.84801465
44MP0003828_pulmonary_edema1.84399369
45MP0002722_abnormal_immune_system1.81621087
46MP0002429_abnormal_blood_cell1.78327748
47MP0009333_abnormal_splenocyte_physiolog1.74963090
48MP0002006_tumorigenesis1.74337437
49MP0003303_peritoneal_inflammation1.71338048
50MP0010155_abnormal_intestine_physiology1.61309768
51MP0001873_stomach_inflammation1.59670950
52MP0002405_respiratory_system_inflammati1.58164319
53MP0002019_abnormal_tumor_incidence1.55106222
54MP0005451_abnormal_body_composition1.51429021
55MP0009278_abnormal_bone_marrow1.51222714
56MP0003183_abnormal_peptide_metabolism1.49935288
57MP0000858_altered_metastatic_potential1.49468404
58MP0000703_abnormal_thymus_morphology1.48116682
59MP0003172_abnormal_lysosome_physiology1.44551798
60MP0002095_abnormal_skin_pigmentation1.43808106
61MP0004381_abnormal_hair_follicle1.43563021
62MP0010307_abnormal_tumor_latency1.39825930
63MP0004147_increased_porphyrin_level1.39690569
64MP0004883_abnormal_blood_vessel1.38923070
65MP0001845_abnormal_inflammatory_respons1.37251937
66MP0004510_myositis1.32168765
67MP0003866_abnormal_defecation1.28611475
68MP0000015_abnormal_ear_pigmentation1.26897018
69MP0005387_immune_system_phenotype1.23888548
70MP0001790_abnormal_immune_system1.23888548
71MP0005164_abnormal_response_to1.19967662
72MP0000343_altered_response_to1.17566131
73MP0008469_abnormal_protein_level1.17391743
74MP0005310_abnormal_salivary_gland1.17111180
75MP0001986_abnormal_taste_sensitivity1.15524781
76MP0002998_abnormal_bone_remodeling1.15039027
77MP0003786_premature_aging1.13796471
78MP0009379_abnormal_foot_pigmentation1.13641871
79MP0001533_abnormal_skeleton_physiology1.13402951
80MP0008004_abnormal_stomach_pH1.12360491
81MP0005409_darkened_coat_color1.09561568
82MP0003656_abnormal_erythrocyte_physiolo1.08956231
83MP0003191_abnormal_cellular_cholesterol1.08550599
84MP0000313_abnormal_cell_death1.07141745
85MP0003186_abnormal_redox_activity1.06838989
86MP0003300_gastrointestinal_ulcer1.01856126
87MP0005166_decreased_susceptibility_to1.00972144
88MP0005390_skeleton_phenotype0.95616680
89MP0003690_abnormal_glial_cell0.92816646
90MP0000350_abnormal_cell_proliferation0.92748516
91MP0003045_fibrosis0.90928655
92MP0003806_abnormal_nucleotide_metabolis0.88694387
93MP0002138_abnormal_hepatobiliary_system0.87424496
94MP0010352_gastrointestinal_tract_polyps0.87337257
95MP0001663_abnormal_digestive_system0.87225530
96MP0006036_abnormal_mitochondrial_physio0.86608686
97MP0003943_abnormal_hepatobiliary_system0.85370568
98MP0003878_abnormal_ear_physiology0.81274869
99MP0005377_hearing/vestibular/ear_phenot0.81274869
100MP0008995_early_reproductive_senescence0.78101790
101MP0009765_abnormal_xenobiotic_induced0.77318997
102MP0001764_abnormal_homeostasis0.76850792
103MP0009763_increased_sensitivity_to0.76240764
104MP0008873_increased_physiological_sensi0.75564767
105MP0004264_abnormal_extraembryonic_tissu0.71864060
106MP0008932_abnormal_embryonic_tissue0.71298281
107MP0001851_eye_inflammation0.71284746
108MP0000249_abnormal_blood_vessel0.66534437
109MP0000598_abnormal_liver_morphology0.65152152
110MP0003795_abnormal_bone_structure0.64608925
111MP0005058_abnormal_lysosome_morphology0.64379048
112MP0001879_abnormal_lymphatic_vessel0.64143590
113MP0003075_altered_response_to0.63982128
114MP0008877_abnormal_DNA_methylation0.63660078
115MP0003567_abnormal_fetal_cardiomyocyte0.63526919
116MP0005319_abnormal_enzyme/_coenzyme0.62985899
117MP0009764_decreased_sensitivity_to0.62966941
118MP0004858_abnormal_nervous_system0.62684003
119MP0004947_skin_inflammation0.60590004
120MP0002332_abnormal_exercise_endurance0.60232773
121MP0005083_abnormal_biliary_tract0.60001906
122MP0008874_decreased_physiological_sensi0.59118450
123MP0003221_abnormal_cardiomyocyte_apopto0.58323468
124MP0001730_embryonic_growth_arrest0.58121308
125MP0003448_altered_tumor_morphology0.56878799
126MP0004130_abnormal_muscle_cell0.56861989
127MP0000371_diluted_coat_color0.56754885
128MP0000477_abnormal_intestine_morphology0.56136019
129MP0000604_amyloidosis0.56035087
130MP0002080_prenatal_lethality0.55016788
131MP0005248_abnormal_Harderian_gland0.54856104
132MP0002933_joint_inflammation0.54411857
133MP0005076_abnormal_cell_differentiation0.53660627
134MP0002133_abnormal_respiratory_system0.52977844
135MP0005388_respiratory_system_phenotype0.52977844
136MP0002928_abnormal_bile_duct0.52313551
137MP0004484_altered_response_of0.49993473

Predicted human phenotypes

RankGene SetZ-score
1Orchitis (HP:0100796)6.06843695
2Thrombocytosis (HP:0001894)5.91384800
3Retrobulbar optic neuritis (HP:0100654)5.63381875
4Optic neuritis (HP:0100653)5.63381875
5Stomatitis (HP:0010280)5.27278198
6Reticulocytopenia (HP:0001896)4.96428281
7Aplastic anemia (HP:0001915)4.61891470
8Elevated erythrocyte sedimentation rate (HP:0003565)4.55618071
9Gastrointestinal infarctions (HP:0005244)4.55042507
10Abnormal number of erythroid precursors (HP:0012131)4.54293875
11Hypochromic microcytic anemia (HP:0004840)4.50631565
12Abnormality of cells of the erythroid lineage (HP:0012130)4.41502158
13Chronic otitis media (HP:0000389)4.34487935
14IgM deficiency (HP:0002850)4.17578860
15Recurrent abscess formation (HP:0002722)4.13943748
16Keratoconjunctivitis sicca (HP:0001097)4.13818827
17Myositis (HP:0100614)3.97420038
18Increased IgE level (HP:0003212)3.91953914
19Petechiae (HP:0000967)3.82594956
20Keratoconjunctivitis (HP:0001096)3.82379057
21Hypochromic anemia (HP:0001931)3.78230327
22Gingivitis (HP:0000230)3.75561652
23Urticaria (HP:0001025)3.74250093
24Recurrent bacterial skin infections (HP:0005406)3.73592578
25Reduced antithrombin III activity (HP:0001976)3.64781220
26Episodic fever (HP:0001954)3.56498396
27Acute lymphatic leukemia (HP:0006721)3.39984101
28Peritonitis (HP:0002586)3.30126782
29Chromsome breakage (HP:0040012)3.27152094
30B lymphocytopenia (HP:0010976)3.22640436
31Abnormality of B cell number (HP:0010975)3.22640436
32Anorexia (HP:0002039)3.16971271
33Papilledema (HP:0001085)3.16569688
34Type I transferrin isoform profile (HP:0003642)3.15015293
35Abnormality of the prostate (HP:0008775)3.08748756
36Prolonged bleeding time (HP:0003010)3.08416429
37Meningitis (HP:0001287)3.08361553
38Eczematoid dermatitis (HP:0000976)3.04546929
39Chronic obstructive pulmonary disease (HP:0006510)3.04471304
40Obstructive lung disease (HP:0006536)3.04471304
41Abnormality of T cell physiology (HP:0011840)3.03906891
42Gingival bleeding (HP:0000225)3.00243215
43Recurrent viral infections (HP:0004429)2.96981420
44Acute myeloid leukemia (HP:0004808)2.94684682
45Pulmonary infiltrates (HP:0002113)2.92470910
46Arterial thrombosis (HP:0004420)2.89569592
47Abnormality of DNA repair (HP:0003254)2.88093601
48Poikiloderma (HP:0001029)2.80123511
49Chromosomal breakage induced by crosslinking agents (HP:0003221)2.79863367
50Pulmonary embolism (HP:0002204)2.78247388
51Epistaxis (HP:0000421)2.77336354
52Cellulitis (HP:0100658)2.75365074
53Pallor (HP:0000980)2.72043656
54Amyloidosis (HP:0011034)2.71798708
55Recurrent fungal infections (HP:0002841)2.70980972
56Abnormal protein glycosylation (HP:0012346)2.69247471
57Abnormal glycosylation (HP:0012345)2.69247471
58Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.69247471
59Abnormal protein N-linked glycosylation (HP:0012347)2.69247471
60Microcytic anemia (HP:0001935)2.67657689
61Granulocytopenia (HP:0001913)2.63189344
62Mediastinal lymphadenopathy (HP:0100721)2.63062074
63T lymphocytopenia (HP:0005403)2.62922114
64Abnormality of T cell number (HP:0011839)2.61025794
65Abnormal platelet function (HP:0011869)2.60538371
66Impaired platelet aggregation (HP:0003540)2.60538371
67Panhypogammaglobulinemia (HP:0003139)2.60500283
68Increased IgM level (HP:0003496)2.56875848
69Myelodysplasia (HP:0002863)2.56277146
70Eosinophilia (HP:0001880)2.53060333
71Pustule (HP:0200039)2.51640812
72Recurrent skin infections (HP:0001581)2.51037803
73Recurrent bronchitis (HP:0002837)2.49531808
74Gangrene (HP:0100758)2.48543696
75Abnormality of the peritoneum (HP:0002585)2.45502894
76Pancytopenia (HP:0001876)2.43670260
7711 pairs of ribs (HP:0000878)2.43556806
78Spontaneous hematomas (HP:0007420)2.41514244
79Chest pain (HP:0100749)2.41388915
80Abnormal delayed hypersensitivity skin test (HP:0002963)2.37967891
81Neutropenia (HP:0001875)2.31996450
82Entropion (HP:0000621)2.31921509
83Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.29525276
84Lymphoma (HP:0002665)2.29300747
85Macrocytic anemia (HP:0001972)2.27978046
86Premature loss of primary teeth (HP:0006323)2.27397084
87Abnormality of macrophages (HP:0004311)2.25986030
88Cutaneous melanoma (HP:0012056)2.23169250
89Metaphyseal cupping (HP:0003021)2.22683704
90Abnormality of chromosome stability (HP:0003220)2.20485921
91Abnormality of the endocardium (HP:0004306)2.20476336
92Abnormality of the columella (HP:0009929)2.20360851
93Abnormality of T cells (HP:0002843)2.20298520
94Abnormality of the heme biosynthetic pathway (HP:0010472)2.20144830
95Glomerulopathy (HP:0100820)2.16952677
96Abnormality of the thoracic spine (HP:0100711)2.13773310
97Difficulty running (HP:0009046)2.12666883
98Hepatosplenomegaly (HP:0001433)2.10671369
99Abnormality of the nasal mucosa (HP:0000433)2.10556904
100Bone marrow hypocellularity (HP:0005528)2.10142304
101Skin ulcer (HP:0200042)2.10018075
102Abnormality of the pericardium (HP:0001697)2.09854558
103Acne (HP:0001061)2.09676781
104Periodontitis (HP:0000704)2.09401554
105Colon cancer (HP:0003003)2.08945974
106Keratitis (HP:0000491)2.08912440
107Interstitial pulmonary disease (HP:0006530)2.08480301
108Abnormality of the renal collecting system (HP:0004742)2.08396714
109Duplicated collecting system (HP:0000081)2.08264979
110Nasal polyposis (HP:0100582)2.07820841
111Slow saccadic eye movements (HP:0000514)2.07383310
112Hemoptysis (HP:0002105)2.06939843
113Purpura (HP:0000979)2.05504402
114Clubbing of toes (HP:0100760)2.05164883
115Segmental peripheral demyelination/remyelination (HP:0003481)2.02576412
116Lymphopenia (HP:0001888)2.02078680
117Hypergammaglobulinemia (HP:0010702)2.02023817
118Pulmonary fibrosis (HP:0002206)2.01885301
119Abnormality of eosinophils (HP:0001879)2.01847118
120Leukocytosis (HP:0001974)2.01230501
121Abnormality of cells of the lymphoid lineage (HP:0012140)2.00018852
122Vertigo (HP:0002321)1.99599041
123Acute hepatic failure (HP:0006554)1.99485054
124Recurrent gram-negative bacterial infections (HP:0005420)1.99026894
125Oral leukoplakia (HP:0002745)1.98503951
126Gastrointestinal inflammation (HP:0004386)1.97510185
127Toxemia of pregnancy (HP:0100603)1.97289575
128Colitis (HP:0002583)1.96692266
129Albinism (HP:0001022)1.96370207
130Vasculitis (HP:0002633)1.95641973
131Osteomyelitis (HP:0002754)1.94745266
132Recurrent pneumonia (HP:0006532)1.94690203
133Abnormality of pyrimidine metabolism (HP:0004353)1.94385092
134Abnormal platelet volume (HP:0011876)1.94154506
135Increased serum ferritin (HP:0003281)1.93938061
136Encephalitis (HP:0002383)1.93210091
137Abnormality of iron homeostasis (HP:0011031)1.92916324
138Birth length less than 3rd percentile (HP:0003561)1.92670175
139Inflammation of the large intestine (HP:0002037)1.92082545
140Abnormality of the pleura (HP:0002103)1.91203540
141Chronic mucocutaneous candidiasis (HP:0002728)1.89354352
142Recurrent cutaneous fungal infections (HP:0011370)1.89354352
143Thyroiditis (HP:0100646)1.89064911
144Agnosia (HP:0010524)1.88933251
145Hypermelanotic macule (HP:0001034)1.88439337
146Amaurosis fugax (HP:0100576)1.87903430
147Hypoplasia of the thymus (HP:0000778)1.87317975
148Thoracic kyphosis (HP:0002942)1.85997989
149IgG deficiency (HP:0004315)1.85948019
150Polycythemia (HP:0001901)1.85612553
151Sepsis (HP:0100806)1.85242403
152Skin rash (HP:0000988)1.85150645
153Subacute progressive viral hepatitis (HP:0006572)1.78045921
154Viral hepatitis (HP:0006562)1.75774596
155Recurrent sinusitis (HP:0011108)1.74995409
156Polyneuropathy (HP:0001271)1.74706088
157Recurrent lower respiratory tract infections (HP:0002783)1.74516495

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.58601954
2FLT33.55384552
3KIT3.48303689
4PIM22.81869151
5WEE12.80070851
6TEC2.72779814
7CSK2.70498897
8EEF2K2.57435143
9IRAK42.57021803
10EPHB12.56864512
11MAP4K12.49518534
12BTK2.39879447
13BRSK22.22333184
14TAOK12.18508743
15CDC72.11973633
16TAOK32.04760180
17MAP3K31.93613184
18KDR1.90869626
19CSF1R1.86053800
20PRPF4B1.75923542
21MAP2K31.74189068
22FES1.65021550
23FGR1.63949697
24PKN21.56585019
25BUB11.55790286
26SCYL21.55271686
27KSR21.49070507
28SIK31.48879260
29JAK21.47732767
30VRK11.46956476
31EIF2AK31.46270154
32MAP3K121.45827839
33NME21.42873675
34TGFBR11.39153490
35MAP3K11.38907051
36RPS6KB21.35706548
37SYK1.35064583
38EIF2AK11.31733753
39TNIK1.28856538
40YES11.28742297
41IRAK11.28158926
42CCNB11.28112327
43TESK21.22721660
44ATR1.21785739
45CDK71.20050800
46ZAP701.18397593
47TBK11.15928061
48BLK1.15473433
49JAK11.13622746
50ACVR1B1.13590614
51MAP3K61.13318368
52MARK21.12634052
53NEK21.12044638
54IRAK21.11767744
55PIM11.11507982
56PTK61.10202053
57CDK191.09505602
58MARK31.07859595
59PRKD21.06804351
60CLK11.05888948
61TRPM71.04863297
62MAPKAPK31.02678456
63BRSK11.02076127
64TSSK61.00760017
65ERN11.00103740
66LRRK20.97657690
67PASK0.97144152
68SRPK10.95720398
69DYRK30.95148684
70SIK20.94121936
71MAP3K130.93530274
72MAP2K40.92126998
73TAOK20.91726809
74MATK0.91408509
75MAPK40.89204815
76CDK80.88369917
77TXK0.86094081
78TRIB30.86049306
79IKBKE0.85465128
80LYN0.85287981
81PDK10.83824762
82MKNK10.83383931
83GRK60.83171555
84TYK20.82623964
85ITK0.81647249
86EPHA30.79869933
87RPS6KA60.79788635
88JAK30.79250246
89DAPK10.78752800
90MAP3K20.78548738
91PDPK10.77907992
92TIE10.77214827
93PAK40.77150216
94RAF10.74430517
95CDK40.73559888
96RPS6KC10.72953165
97RPS6KL10.72953165
98SMG10.71948594
99RPS6KA40.71097922
100PTK2B0.71022550
101LCK0.70489916
102MAPKAPK50.70181997
103STK100.70061108
104FYN0.69890864
105MAP3K50.69213098
106IRAK30.68602520
107MAP3K70.67894351
108STK110.65318661
109BMPR20.63716071
110BCKDK0.63053071
111TLK10.61646422
112STK380.60907813
113MAP3K110.60499505
114MAP2K60.59176258
115HCK0.59010305
116SIK10.58645512
117RET0.58037918
118DYRK1B0.57730871
119MAPK120.57665545
120FGFR40.56836083
121MAP3K80.55580379
122CDC42BPA0.54642535
123AURKB0.54174437
124TNK20.54014743
125DAPK20.53993315
126PRKG20.53508615
127FGFR30.52153598
128ADRBK20.50471929
129RPS6KA20.50218393
130IKBKB0.50189400
131HIPK20.49740159
132SGK30.49664874
133RIPK40.48897366
134PLK10.48633100
135STK40.47552208
136KSR10.47452492
137MAPK110.47296402
138CAMKK20.46114516
139NLK0.44669088
140PRKCQ0.44506785
141MAP3K140.43757499
142CDK60.43382943
143MAPK70.42480797
144ALK0.42322842
145PIK3CG0.42308680
146RPS6KB10.41406368
147MAPKAPK20.41031543
148PRKCZ0.40654262
149EIF2AK20.40547735
150MYLK0.37014719
151MKNK20.36708532
152ILK0.35228687
153TGFBR20.35113178
154CSNK2A10.34844418
155WNK10.31729299
156PRKCD0.30394774
157SGK20.29607878
158PRKCH0.26180382

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.50618653
2Mismatch repair_Homo sapiens_hsa034303.73904252
3Ribosome_Homo sapiens_hsa030103.58935417
4Base excision repair_Homo sapiens_hsa034103.30237816
5Homologous recombination_Homo sapiens_hsa034403.05995226
6Staphylococcus aureus infection_Homo sapiens_hsa051502.93152849
7Non-homologous end-joining_Homo sapiens_hsa034502.64790181
8Nucleotide excision repair_Homo sapiens_hsa034202.25536436
9Spliceosome_Homo sapiens_hsa030402.17140470
10Pyrimidine metabolism_Homo sapiens_hsa002402.03741384
11Graft-versus-host disease_Homo sapiens_hsa053322.01680933
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.91370082
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.83373383
14Primary immunodeficiency_Homo sapiens_hsa053401.81986938
15Cell cycle_Homo sapiens_hsa041101.80357286
16Pentose phosphate pathway_Homo sapiens_hsa000301.80172031
17Fanconi anemia pathway_Homo sapiens_hsa034601.78749003
18Chemokine signaling pathway_Homo sapiens_hsa040621.78691069
19Autoimmune thyroid disease_Homo sapiens_hsa053201.78034777
20N-Glycan biosynthesis_Homo sapiens_hsa005101.75758168
21Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.72353760
22Leishmaniasis_Homo sapiens_hsa051401.69147554
23Protein export_Homo sapiens_hsa030601.65747522
24One carbon pool by folate_Homo sapiens_hsa006701.57457889
25Proteasome_Homo sapiens_hsa030501.54031656
26T cell receptor signaling pathway_Homo sapiens_hsa046601.51968456
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.46428829
28RNA polymerase_Homo sapiens_hsa030201.44552583
29Phagosome_Homo sapiens_hsa041451.43522802
30RNA degradation_Homo sapiens_hsa030181.41992445
31Type I diabetes mellitus_Homo sapiens_hsa049401.41501721
32African trypanosomiasis_Homo sapiens_hsa051431.41232733
33RNA transport_Homo sapiens_hsa030131.40756598
34Herpes simplex infection_Homo sapiens_hsa051681.38601894
35Antigen processing and presentation_Homo sapiens_hsa046121.36012233
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.31131644
37TNF signaling pathway_Homo sapiens_hsa046681.30670902
38Hematopoietic cell lineage_Homo sapiens_hsa046401.30512213
39Viral myocarditis_Homo sapiens_hsa054161.28778833
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.21594547
41Other glycan degradation_Homo sapiens_hsa005111.20510933
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.19428586
43B cell receptor signaling pathway_Homo sapiens_hsa046621.18589733
44Measles_Homo sapiens_hsa051621.17707400
45Hepatitis C_Homo sapiens_hsa051601.17703281
46Legionellosis_Homo sapiens_hsa051341.17658957
47Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.13369189
48Transcriptional misregulation in cancer_Homo sapiens_hsa052021.10436917
49Pancreatic cancer_Homo sapiens_hsa052121.08993568
50Purine metabolism_Homo sapiens_hsa002301.08337915
51Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.06117838
52VEGF signaling pathway_Homo sapiens_hsa043701.04928753
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01406797
54Acute myeloid leukemia_Homo sapiens_hsa052211.00830462
55p53 signaling pathway_Homo sapiens_hsa041150.99881579
56NF-kappa B signaling pathway_Homo sapiens_hsa040640.93452782
57Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.92539676
58Galactose metabolism_Homo sapiens_hsa000520.91806349
59Prolactin signaling pathway_Homo sapiens_hsa049170.89250866
60Renal cell carcinoma_Homo sapiens_hsa052110.88104561
61Pertussis_Homo sapiens_hsa051330.88011249
62Endocytosis_Homo sapiens_hsa041440.87275750
63Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.85499603
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83294524
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.83236549
66Thyroid cancer_Homo sapiens_hsa052160.81801480
67Shigellosis_Homo sapiens_hsa051310.81443169
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.80376732
69Renin-angiotensin system_Homo sapiens_hsa046140.79300790
70Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78875817
71Epstein-Barr virus infection_Homo sapiens_hsa051690.76513074
72Jak-STAT signaling pathway_Homo sapiens_hsa046300.76374747
73Toll-like receptor signaling pathway_Homo sapiens_hsa046200.75775434
74FoxO signaling pathway_Homo sapiens_hsa040680.75661581
75Influenza A_Homo sapiens_hsa051640.74747458
76Osteoclast differentiation_Homo sapiens_hsa043800.74741618
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.74501430
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.74299004
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.74165530
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.74108261
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.73501870
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72994866
83Hepatitis B_Homo sapiens_hsa051610.72789053
84Amoebiasis_Homo sapiens_hsa051460.72438984
85Folate biosynthesis_Homo sapiens_hsa007900.71851158
86Cyanoamino acid metabolism_Homo sapiens_hsa004600.71787245
87Notch signaling pathway_Homo sapiens_hsa043300.71750817
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71181699
89Glycosaminoglycan degradation_Homo sapiens_hsa005310.70848329
90Endometrial cancer_Homo sapiens_hsa052130.70675679
91Rheumatoid arthritis_Homo sapiens_hsa053230.70180314
92Platelet activation_Homo sapiens_hsa046110.68916465
93Systemic lupus erythematosus_Homo sapiens_hsa053220.68328087
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68029396
95Choline metabolism in cancer_Homo sapiens_hsa052310.67550804
96Intestinal immune network for IgA production_Homo sapiens_hsa046720.67286099
97Sulfur relay system_Homo sapiens_hsa041220.66517419
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.65968962
99Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65308998
100Apoptosis_Homo sapiens_hsa042100.65096056
101Regulation of autophagy_Homo sapiens_hsa041400.65019004
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63972307
103Basal transcription factors_Homo sapiens_hsa030220.63721950
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63295038
105GnRH signaling pathway_Homo sapiens_hsa049120.60795254
106Dorso-ventral axis formation_Homo sapiens_hsa043200.60786725
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60717063
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60675501
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.60666927
110Viral carcinogenesis_Homo sapiens_hsa052030.59591842
111Leukocyte transendothelial migration_Homo sapiens_hsa046700.58028910
112Type II diabetes mellitus_Homo sapiens_hsa049300.58014197
113Glutathione metabolism_Homo sapiens_hsa004800.57059852
114HIF-1 signaling pathway_Homo sapiens_hsa040660.56012167
115Insulin resistance_Homo sapiens_hsa049310.55822913
116Toxoplasmosis_Homo sapiens_hsa051450.54483304
117Lysosome_Homo sapiens_hsa041420.54111114
118Glycerophospholipid metabolism_Homo sapiens_hsa005640.53762506
119Colorectal cancer_Homo sapiens_hsa052100.53514608
120Rap1 signaling pathway_Homo sapiens_hsa040150.53102672
121Asthma_Homo sapiens_hsa053100.51632737
122Inositol phosphate metabolism_Homo sapiens_hsa005620.51030141
123Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.50742730
124Tuberculosis_Homo sapiens_hsa051520.50647930
125Chronic myeloid leukemia_Homo sapiens_hsa052200.50362828
126Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49451304
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49346949
128mTOR signaling pathway_Homo sapiens_hsa041500.49198150
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49180047
130MAPK signaling pathway_Homo sapiens_hsa040100.48999204
131Small cell lung cancer_Homo sapiens_hsa052220.48727665
132Allograft rejection_Homo sapiens_hsa053300.48465800
133mRNA surveillance pathway_Homo sapiens_hsa030150.45964254
134Selenocompound metabolism_Homo sapiens_hsa004500.45544839
135Malaria_Homo sapiens_hsa051440.44459666
136Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42921791
137Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.42535290
138HTLV-I infection_Homo sapiens_hsa051660.42196403
139ErbB signaling pathway_Homo sapiens_hsa040120.42097419
140Insulin signaling pathway_Homo sapiens_hsa049100.42035771
141Biosynthesis of amino acids_Homo sapiens_hsa012300.41155857
142ABC transporters_Homo sapiens_hsa020100.39864160
143Non-small cell lung cancer_Homo sapiens_hsa052230.38805129
144Prostate cancer_Homo sapiens_hsa052150.37163630
145Starch and sucrose metabolism_Homo sapiens_hsa005000.36460134
146Salmonella infection_Homo sapiens_hsa051320.36016374
147Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.34914095
148Carbon metabolism_Homo sapiens_hsa012000.32429548
149Central carbon metabolism in cancer_Homo sapiens_hsa052300.31098347
150Cysteine and methionine metabolism_Homo sapiens_hsa002700.27860986
151Neurotrophin signaling pathway_Homo sapiens_hsa047220.24097677

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