ADGRG7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)9.53632126
2UDP-N-acetylglucosamine metabolic process (GO:0006047)8.37975759
3angiotensin maturation (GO:0002003)7.82580900
4intestinal cholesterol absorption (GO:0030299)7.44399985
5epoxygenase P450 pathway (GO:0019373)7.26622726
6lipoprotein transport (GO:0042953)7.21301014
7regulation of guanylate cyclase activity (GO:0031282)6.58118913
8maintenance of gastrointestinal epithelium (GO:0030277)6.52088307
9bundle of His cell to Purkinje myocyte communication (GO:0086069)6.25351111
10NADH metabolic process (GO:0006734)6.02875522
11fat-soluble vitamin biosynthetic process (GO:0042362)5.96131076
12transcytosis (GO:0045056)5.86607079
13intestinal epithelial cell development (GO:0060576)5.69139385
14actin filament depolymerization (GO:0030042)5.67207610
15vitamin A metabolic process (GO:0006776)5.43942290
16O-glycan processing (GO:0016266)5.26455354
17positive regulation of guanylate cyclase activity (GO:0031284)5.19472513
18cellular glucuronidation (GO:0052695)5.18691356
19glucuronate metabolic process (GO:0019585)5.14308376
20uronic acid metabolic process (GO:0006063)5.14308376
21drug metabolic process (GO:0017144)5.14162648
22very-low-density lipoprotein particle assembly (GO:0034379)5.09023273
23digestive system process (GO:0022600)4.95113590
24regulation of cellular extravasation (GO:0002691)4.93914229
25epithelial structure maintenance (GO:0010669)4.93275316
26urea cycle (GO:0000050)4.92820130
27fructose metabolic process (GO:0006000)4.92316630
28regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.92253735
29endocrine process (GO:0050886)4.92253735
30regulation of systemic arterial blood pressure by hormone (GO:0001990)4.92253735
31sulfate transmembrane transport (GO:1902358)4.90087797
32urea metabolic process (GO:0019627)4.86344047
333-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.82960402
34purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.82960402
35flavonoid metabolic process (GO:0009812)4.61436935
36striated muscle atrophy (GO:0014891)4.54296099
37nitrogen cycle metabolic process (GO:0071941)4.44693282
38regulation of systemic arterial blood pressure (GO:0003073)4.44493484
39regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.43872223
40L-fucose catabolic process (GO:0042355)4.41249680
41fucose catabolic process (GO:0019317)4.41249680
42L-fucose metabolic process (GO:0042354)4.41249680
43exogenous drug catabolic process (GO:0042738)4.41049337
44thrombin receptor signaling pathway (GO:0070493)4.35681315
45detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)4.22299838
46diacylglycerol metabolic process (GO:0046339)4.20364841
47hemidesmosome assembly (GO:0031581)4.19822283
48nucleotide-sugar metabolic process (GO:0009225)4.13521703
49hepatocyte apoptotic process (GO:0097284)4.05251943
50adhesion of symbiont to host cell (GO:0044650)4.04958428
51virion attachment to host cell (GO:0019062)4.04958428
52regulation of bile acid biosynthetic process (GO:0070857)4.04701955
53regulation of cGMP biosynthetic process (GO:0030826)4.02270971
54sulfate transport (GO:0008272)3.94442210
55skeletal muscle adaptation (GO:0043501)3.94070638
56regulation of vitamin metabolic process (GO:0030656)3.93140677
57galactose catabolic process (GO:0019388)3.91929672
58N-glycan processing (GO:0006491)3.88494029
59bile acid metabolic process (GO:0008206)3.88420274
60bile acid and bile salt transport (GO:0015721)3.87744569
61drug catabolic process (GO:0042737)3.87388323
62sperm capacitation (GO:0048240)3.85440550
63nucleotide-sugar biosynthetic process (GO:0009226)3.84840423
64epithelial cell-cell adhesion (GO:0090136)3.84071007
65receptor guanylyl cyclase signaling pathway (GO:0007168)3.83113032
66sulfation (GO:0051923)3.82098398
67arginine metabolic process (GO:0006525)3.81495043
68muscle atrophy (GO:0014889)3.79352977
69glycolipid catabolic process (GO:0019377)3.79330532
70glycosphingolipid catabolic process (GO:0046479)3.77226121
71midgut development (GO:0007494)3.76785312
72bicarbonate transport (GO:0015701)3.75477701
73regulation of cholesterol esterification (GO:0010872)3.73616439
74fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.71873490
75renal system process involved in regulation of blood volume (GO:0001977)3.70197224
76high-density lipoprotein particle remodeling (GO:0034375)3.69891727
77glutamine family amino acid biosynthetic process (GO:0009084)3.69749496
78alkaloid metabolic process (GO:0009820)3.68845295
79homocysteine metabolic process (GO:0050667)3.63623418
80glucose 6-phosphate metabolic process (GO:0051156)3.62217644
81positive regulation of glycoprotein biosynthetic process (GO:0010560)3.57883665
82fat-soluble vitamin metabolic process (GO:0006775)3.57640397
83vitamin transmembrane transport (GO:0035461)3.56022948
84regulation of chemokine secretion (GO:0090196)3.55452011
85Peyers patch development (GO:0048541)3.52566964
86mucosal-associated lymphoid tissue development (GO:0048537)3.52566964
87sulfur compound transport (GO:0072348)3.50828145
88protein-lipid complex remodeling (GO:0034368)3.47462683
89macromolecular complex remodeling (GO:0034367)3.47462683
90plasma lipoprotein particle remodeling (GO:0034369)3.47462683
91negative regulation of steroid metabolic process (GO:0045939)3.47247801
92mRNA modification (GO:0016556)3.45907143
93positive regulation of triglyceride lipase activity (GO:0061365)3.44079581
94positive regulation of lipoprotein lipase activity (GO:0051006)3.44079581
95drinking behavior (GO:0042756)3.43425083
96antibacterial humoral response (GO:0019731)3.38971620
97regulation of cholesterol homeostasis (GO:2000188)3.38152208
98regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.37837575
99positive regulation of actin filament depolymerization (GO:0030836)3.36970211
100negative regulation of steroid biosynthetic process (GO:0010894)3.36636971
101antimicrobial humoral response (GO:0019730)3.36173763
102omega-hydroxylase P450 pathway (GO:0097267)3.35393909
103hormone catabolic process (GO:0042447)3.35049070
104positive regulation of pseudopodium assembly (GO:0031274)3.34236817
105regulation of cGMP metabolic process (GO:0030823)3.33526797
106digestion (GO:0007586)3.31742074
107vitamin transport (GO:0051180)3.30615170
108protein O-linked glycosylation (GO:0006493)3.30330656
109positive regulation of lipid catabolic process (GO:0050996)3.29522975
110cellular response to nitric oxide (GO:0071732)3.28135874
111cellular response to hepatocyte growth factor stimulus (GO:0035729)3.27439934
112response to hepatocyte growth factor (GO:0035728)3.27439934
113plasma lipoprotein particle organization (GO:0071827)3.23619823
114reverse cholesterol transport (GO:0043691)3.19653558
115sulfur amino acid catabolic process (GO:0000098)3.18720235
116positive regulation of glycoprotein metabolic process (GO:1903020)3.17909778
117regulation of actin nucleation (GO:0051125)3.17221782
118glycerol metabolic process (GO:0006071)3.17104044
119ethanol oxidation (GO:0006069)3.16699435
120vitamin biosynthetic process (GO:0009110)3.16653255
121transepithelial transport (GO:0070633)3.15571366
122vitamin D metabolic process (GO:0042359)3.14837533
123thyroid hormone metabolic process (GO:0042403)3.14820618
124adhesion of symbiont to host (GO:0044406)3.14462355
125interferon-gamma secretion (GO:0072643)3.11169089
126defense response to fungus (GO:0050832)3.09887007
127negative regulation of thymocyte apoptotic process (GO:0070244)3.09501005
128protein-lipid complex subunit organization (GO:0071825)3.07185311
129antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.04943080
130antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.04943080
131citrulline biosynthetic process (GO:0019240)3.04180518
132positive regulation of cGMP biosynthetic process (GO:0030828)3.03328841
133cholesterol efflux (GO:0033344)3.03224107
134fucose metabolic process (GO:0006004)3.02950088
135activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO3.01842491
136hexose catabolic process (GO:0019320)3.01758269
137ceramide catabolic process (GO:0046514)3.01095770
138negative regulation of hormone metabolic process (GO:0032351)3.00209919
139L-ascorbic acid metabolic process (GO:0019852)2.98534984
140glycosylceramide metabolic process (GO:0006677)2.98259143
141regulation of pseudopodium assembly (GO:0031272)2.98109905
142nucleoside diphosphate biosynthetic process (GO:0009133)2.97550530
143plasma lipoprotein particle assembly (GO:0034377)2.96835908
144modified amino acid transport (GO:0072337)2.96289430
145phospholipid efflux (GO:0033700)2.95747476
146negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.95057783
147regulation of triglyceride catabolic process (GO:0010896)2.93733294
148peptide catabolic process (GO:0043171)2.93118053
149lipoprotein metabolic process (GO:0042157)2.91111161
150protein-lipid complex assembly (GO:0065005)2.85064602
151phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.83990574
152calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.83399523
153negative regulation of cholesterol transport (GO:0032375)2.77856010
154negative regulation of sterol transport (GO:0032372)2.77856010
155triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.77243689
156peptide hormone processing (GO:0016486)2.76654106
157galactose metabolic process (GO:0006012)2.75181936
158regulation of respiratory burst (GO:0060263)2.71793512
159ventricular cardiac muscle cell action potential (GO:0086005)2.71112265
160desmosome organization (GO:0002934)2.70520087
161GDP-mannose metabolic process (GO:0019673)2.70406547
162cGMP-mediated signaling (GO:0019934)2.69290387
163hypotonic response (GO:0006971)2.69218669
164lung secretory cell differentiation (GO:0061140)2.68455256
165tight junction assembly (GO:0070830)2.67919141
166lipid translocation (GO:0034204)2.67812918
167phospholipid translocation (GO:0045332)2.67812918
168drug transport (GO:0015893)2.67575546
169cholesterol homeostasis (GO:0042632)2.65861349
170neural tube formation (GO:0001841)2.65605009
171sterol homeostasis (GO:0055092)2.65136922
172killing of cells of other organism (GO:0031640)2.64789799

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.64500196
2CDX2_20551321_ChIP-Seq_CACO-2_Human5.95672700
3SOX2_27498859_Chip-Seq_STOMACH_Mouse4.14075707
4GATA4_25053715_ChIP-Seq_YYC3_Human3.26314379
5GATA6_25053715_ChIP-Seq_YYC3_Human3.11679581
6SOX2_20726797_ChIP-Seq_SW620_Human2.98129489
7STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.80119628
8SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.75940864
9HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.74932039
10CDX2_19796622_ChIP-Seq_MESCs_Mouse2.69091003
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.60117921
12STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.51436843
13IRF8_22096565_ChIP-ChIP_GC-B_Human2.35541047
14ZNF263_19887448_ChIP-Seq_K562_Human2.31766537
15PPARA_22158963_ChIP-Seq_LIVER_Mouse2.23888806
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.17301025
17KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.09117949
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.08359428
19FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.05953972
20MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.04127583
21CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.01211193
22FOXO3_23340844_ChIP-Seq_DLD1_Human1.97681074
23TCF4_18268006_ChIP-ChIP_LS174T_Human1.97062224
24PPAR_26484153_Chip-Seq_NCI-H1993_Human1.96486171
25RUNX1_27514584_Chip-Seq_MCF-7_Human1.93959662
26PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.91826765
27SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.84980848
28ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.84904885
29FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.84502690
30RXR_22158963_ChIP-Seq_LIVER_Mouse1.83074240
31RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.78242116
32ESR1_20079471_ChIP-ChIP_T-47D_Human1.77811915
33AR_21909140_ChIP-Seq_LNCAP_Human1.77233899
34LXR_22158963_ChIP-Seq_LIVER_Mouse1.73772008
35ESR2_21235772_ChIP-Seq_MCF-7_Human1.73537064
36KLF5_25053715_ChIP-Seq_YYC3_Human1.73536671
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.71544894
38KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.70590046
39FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.66330183
40RACK7_27058665_Chip-Seq_MCF-7_Human1.63416395
41IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.61448654
42GATA1_22025678_ChIP-Seq_K562_Human1.60898890
43RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58789850
44CDX2_22108803_ChIP-Seq_LS180_Human1.56527194
45GATA2_19941826_ChIP-Seq_K562_Human1.55675255
46ATF3_27146783_Chip-Seq_COLON_Human1.54266233
47PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.53820144
48TRIM28_21343339_ChIP-Seq_HEK293_Human1.52337630
49ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.50907365
50MYB_21317192_ChIP-Seq_ERMYB_Mouse1.46716578
51ESR1_21235772_ChIP-Seq_MCF-7_Human1.43037378
52NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.42666931
53STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35572477
54AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.35546834
55SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.34870417
56SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.34870417
57ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.31401975
58NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.30216291
59CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.28764290
60TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27889805
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.26755532
62KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24181386
63PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.21318177
64ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18095337
65VDR_24763502_ChIP-Seq_THP-1_Human1.17987503
66HIF1A_21447827_ChIP-Seq_MCF-7_Human1.17692339
67CLOCK_20551151_ChIP-Seq_293T_Human1.17411521
68CREB1_26743006_Chip-Seq_LNCaP_Human1.16698863
69STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.16312445
70GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14782529
71RXR_22108803_ChIP-Seq_LS180_Human1.14130579
72FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.14124285
73HNF4A_19822575_ChIP-Seq_HepG2_Human1.13846437
74CTNNB1_20460455_ChIP-Seq_HCT116_Human1.10211911
75BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07403066
76GATA2_22383799_ChIP-Seq_G1ME_Mouse1.06232355
77BRD4_27068464_Chip-Seq_AML-cells_Mouse1.03796094
78RUNX1_22412390_ChIP-Seq_EML_Mouse1.03342454
79SALL4_18804426_ChIP-ChIP_XEN_Mouse1.03293092
80IRF8_21731497_ChIP-ChIP_J774_Mouse1.02322894
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.02062870
82GATA1_22383799_ChIP-Seq_G1ME_Mouse1.01958184
83TP53_16413492_ChIP-PET_HCT116_Human1.01522267
84BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.01437185
85ELF5_23300383_ChIP-Seq_T47D_Human1.01278230
86FOXA1_25552417_ChIP-Seq_VCAP_Human1.00439950
87JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00075583
88GATA3_24758297_ChIP-Seq_MCF-7_Human0.99465171
89VDR_21846776_ChIP-Seq_THP-1_Human0.99444127
90P63_26484246_Chip-Seq_KERATINOCYTES_Human0.99243872
91EGR1_19032775_ChIP-ChIP_M12_Human0.98174792
92PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.98118326
93EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.98079411
94FOXA2_19822575_ChIP-Seq_HepG2_Human0.97639918
95CEBPB_22108803_ChIP-Seq_LS180_Human0.96764897
96SMAD3_21741376_ChIP-Seq_HESCs_Human0.94435278
97NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94283393
98GATA2_21666600_ChIP-Seq_HMVEC_Human0.93104568
99FOXM1_26456572_ChIP-Seq_MCF-7_Human0.92625039
100TP63_23658742_ChIP-Seq_EP156T_Human0.91687712
101NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.90713613
102FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89210411
103GATA1_19941826_ChIP-Seq_K562_Human0.87789064
104GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.86949018
105TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.86314710
106EGR1_23403033_ChIP-Seq_LIVER_Mouse0.86051952
107ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.84686490
108TCF3_18692474_ChIP-Seq_MEFs_Mouse0.84516421
109NANOG_20526341_ChIP-Seq_ESCs_Human0.84414389
110HNFA_21074721_ChIP-Seq_CACO-2_Human0.84136597
111CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.83628696
112Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.83614041
113TCF4_22108803_ChIP-Seq_LS180_Human0.82942202
114PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.81615950
115JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.81589282
116VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.81021816
117CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.80398801
118KAP1_22055183_ChIP-Seq_ESCs_Mouse0.80230879
119NR3C1_21868756_ChIP-Seq_MCF10A_Human0.79811232
120BCAT_22108803_ChIP-Seq_LS180_Human0.79577520
121PIAS1_25552417_ChIP-Seq_VCAP_Human0.78685347
122TCF7_22412390_ChIP-Seq_EML_Mouse0.78377222
123VDR_24787735_ChIP-Seq_THP-1_Human0.78286063
124FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.77717857
125AUTS2_25519132_ChIP-Seq_293T-REX_Human0.77098796
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.77089873
127LXR_22292898_ChIP-Seq_THP-1_Human0.76922557
128GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.76862812
129UTX_26944678_Chip-Seq_JUKART_Human0.76633273
130SPI1_23127762_ChIP-Seq_K562_Human0.75892764
131CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.75667946
132CJUN_26792858_Chip-Seq_BT549_Human0.75589624
133VDR_22108803_ChIP-Seq_LS180_Human0.75382828
134LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.75159620
135GATA1_19941827_ChIP-Seq_MEL_Mouse0.75022235
136CBP_21632823_ChIP-Seq_H3396_Human0.74375877
137SOX2_22085726_ChIP-Seq_NPCs_Mouse0.72219743
138SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.69873956
139PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.68975770
140TP53_18474530_ChIP-ChIP_U2OS_Human0.67722006
141CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.67629808
142NFYA_21822215_ChIP-Seq_K562_Human0.67542123

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle5.86673837
2MP0005360_urolithiasis5.20155707
3MP0004264_abnormal_extraembryonic_tissu4.73271185
4MP0003866_abnormal_defecation4.50531902
5MP0001666_abnormal_nutrient_absorption4.40298031
6MP0003300_gastrointestinal_ulcer3.70730565
7MP0000462_abnormal_digestive_system3.31161760
8MP0010155_abnormal_intestine_physiology3.10783332
9MP0010352_gastrointestinal_tract_polyps2.79486950
10MP0005085_abnormal_gallbladder_physiolo2.76055233
11MP0001663_abnormal_digestive_system2.72844462
12MP0001873_stomach_inflammation2.72204625
13MP0003252_abnormal_bile_duct2.59634126
14MP0005381_digestive/alimentary_phenotyp2.52463126
15MP0000537_abnormal_urethra_morphology2.46366464
16MP0000490_abnormal_crypts_of2.41884916
17MP0000477_abnormal_intestine_morphology2.32960803
18MP0004147_increased_porphyrin_level2.30273289
19MP0006054_spinal_hemorrhage2.26960518
20MP0003183_abnormal_peptide_metabolism2.24321973
21MP0001664_abnormal_digestion2.22732015
22MP0005409_darkened_coat_color1.99965929
23MP0002822_catalepsy1.96026616
24MP0008875_abnormal_xenobiotic_pharmacok1.95488919
25MP0003705_abnormal_hypodermis_morpholog1.86973438
26MP0005377_hearing/vestibular/ear_phenot1.83638210
27MP0003878_abnormal_ear_physiology1.83638210
28MP0009840_abnormal_foam_cell1.83233033
29MP0002139_abnormal_hepatobiliary_system1.80681440
30MP0002009_preneoplasia1.73396090
31MP0000538_abnormal_urinary_bladder1.64845824
32MP0002254_reproductive_system_inflammat1.64150068
33MP0005365_abnormal_bile_salt1.63839635
34MP0010678_abnormal_skin_adnexa1.62946636
35MP0005310_abnormal_salivary_gland1.53781045
36MP0010329_abnormal_lipoprotein_level1.52378807
37MP0002166_altered_tumor_susceptibility1.44591670
38MP0004858_abnormal_nervous_system1.43276090
39MP0001765_abnormal_ion_homeostasis1.40958161
40MP0004043_abnormal_pH_regulation1.40627226
41MP0002796_impaired_skin_barrier1.38877749
42MP0001849_ear_inflammation1.32969615
43MP0002006_tumorigenesis1.32114859
44MP0003868_abnormal_feces_composition1.29498035
45MP0009379_abnormal_foot_pigmentation1.21965913
46MP0000566_synostosis1.21929562
47MP0005167_abnormal_blood-brain_barrier1.21788125
48MP0002098_abnormal_vibrissa_morphology1.19564131
49MP0005501_abnormal_skin_physiology1.19543064
50MP0000465_gastrointestinal_hemorrhage1.18872563
51MP0004947_skin_inflammation1.16655115
52MP0004782_abnormal_surfactant_physiolog1.15637629
53MP0003453_abnormal_keratinocyte_physiol1.14537052
54MP0000467_abnormal_esophagus_morphology1.10221389
55MP0005670_abnormal_white_adipose1.09870503
56MP0001188_hyperpigmentation1.09673925
57MP0000678_abnormal_parathyroid_gland1.07806638
58MP0009643_abnormal_urine_homeostasis1.04219219
59MP0005636_abnormal_mineral_homeostasis1.02493204
60MP0005166_decreased_susceptibility_to1.01602914
61MP0001501_abnormal_sleep_pattern1.00660258
62MP0000470_abnormal_stomach_morphology0.99988405
63MP0002971_abnormal_brown_adipose0.97780667
64MP0004019_abnormal_vitamin_homeostasis0.95498318
65MP0009697_abnormal_copulation0.95175824
66MP0005584_abnormal_enzyme/coenzyme_acti0.95026111
67MP0001216_abnormal_epidermal_layer0.93397779
68MP0004270_analgesia0.93345930
69MP0000516_abnormal_urinary_system0.86325225
70MP0005367_renal/urinary_system_phenotyp0.86325225
71MP0008872_abnormal_physiological_respon0.85397404
72MP0002277_abnormal_respiratory_mucosa0.85206940
73MP0003045_fibrosis0.85173313
74MP0003879_abnormal_hair_cell0.85110171
75MP0008775_abnormal_heart_ventricle0.85103727
76MP0002138_abnormal_hepatobiliary_system0.83200593
77MP0003566_abnormal_cell_adhesion0.83025263
78MP0005535_abnormal_body_temperature0.82008199
79MP0009785_altered_susceptibility_to0.79995940
80MP0003436_decreased_susceptibility_to0.78839995
81MP0004215_abnormal_myocardial_fiber0.78423470
82MP0002060_abnormal_skin_morphology0.76864226
83MP0000609_abnormal_liver_physiology0.76603937
84MP0001845_abnormal_inflammatory_respons0.75882266
85MP0001485_abnormal_pinna_reflex0.75753186
86MP0000613_abnormal_salivary_gland0.75508635
87MP0004145_abnormal_muscle_electrophysio0.74844982
88MP0000230_abnormal_systemic_arterial0.74792521
89MP0005025_abnormal_response_to0.74757914
90MP0002089_abnormal_postnatal_growth/wei0.74423767
91MP0009115_abnormal_fat_cell0.73837821
92MP0003315_abnormal_perineum_morphology0.73381601
93MP0003283_abnormal_digestive_organ0.73219939
94MP0005464_abnormal_platelet_physiology0.72620030
95MP0009384_cardiac_valve_regurgitation0.72471561
96MP0003191_abnormal_cellular_cholesterol0.71080029
97MP0003693_abnormal_embryo_hatching0.69916121
98MP0000377_abnormal_hair_follicle0.69570567
99MP0000604_amyloidosis0.69503213
100MP0009642_abnormal_blood_homeostasis0.68106349
101MP0005448_abnormal_energy_balance0.66612687
102MP0002136_abnormal_kidney_physiology0.65599928
103MP0003806_abnormal_nucleotide_metabolis0.64049145
104MP0005451_abnormal_body_composition0.63997066
105MP0003329_amyloid_beta_deposits0.63870542
106MP0001881_abnormal_mammary_gland0.63296601
107MP0005319_abnormal_enzyme/_coenzyme0.62860127
108MP0010771_integument_phenotype0.61734353
109MP0003941_abnormal_skin_development0.61210497
110MP0001764_abnormal_homeostasis0.60733072
111MP0002876_abnormal_thyroid_physiology0.59205325
112MP0003718_maternal_effect0.58687060
113MP0003303_peritoneal_inflammation0.58514667
114MP0002896_abnormal_bone_mineralization0.58045403
115MP0000383_abnormal_hair_follicle0.56956287
116MP0006138_congestive_heart_failure0.56783627
117MP0005666_abnormal_adipose_tissue0.56690192
118MP0005334_abnormal_fat_pad0.56423390
119MP0002148_abnormal_hypersensitivity_rea0.54969023
120MP0000249_abnormal_blood_vessel0.54899580
121MP0008004_abnormal_stomach_pH0.53314375
122MP0009780_abnormal_chondrocyte_physiolo0.53257089
123MP0002396_abnormal_hematopoietic_system0.51384548
124MP0002118_abnormal_lipid_homeostasis0.50429259
125MP0002132_abnormal_respiratory_system0.50324492
126MP0003724_increased_susceptibility_to0.49898420
127MP0008873_increased_physiological_sensi0.49881386
128MP0009053_abnormal_anal_canal0.48618144
129MP0005084_abnormal_gallbladder_morpholo0.47379804
130MP0005395_other_phenotype0.47054336
131MP0009764_decreased_sensitivity_to0.47028909
132MP0001756_abnormal_urination0.46827889
133MP0005165_increased_susceptibility_to0.46760454
134MP0002078_abnormal_glucose_homeostasis0.46416181
135MP0009765_abnormal_xenobiotic_induced0.46248415
136MP0003953_abnormal_hormone_level0.45318729
137MP0010307_abnormal_tumor_latency0.43647298
138MP0008469_abnormal_protein_level0.43285585
139MP0005332_abnormal_amino_acid0.42149105
140MP0004510_myositis0.41470284

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)8.77585796
2Right ventricular cardiomyopathy (HP:0011663)6.43821433
3Acanthocytosis (HP:0001927)4.92870018
4Malnutrition (HP:0004395)4.72112235
5Abnormality of glutamine family amino acid metabolism (HP:0010902)4.65228858
6Systemic lupus erythematosus (HP:0002725)4.61379552
7Hyperactive renin-angiotensin system (HP:0000841)4.33953529
8Abdominal distention (HP:0003270)4.25157260
9Chronic diarrhea (HP:0002028)4.23966238
10Abnormality of proline metabolism (HP:0010907)4.12609393
11Hydroxyprolinuria (HP:0003080)4.12609393
12Conjugated hyperbilirubinemia (HP:0002908)3.98526397
13Metabolic alkalosis (HP:0200114)3.96061091
14Hypobetalipoproteinemia (HP:0003563)3.77109578
15Confusion (HP:0001289)3.72745877
16Proximal tubulopathy (HP:0000114)3.67635188
17Gastrointestinal dysmotility (HP:0002579)3.61160381
18Glycosuria (HP:0003076)3.59803590
19Abnormality of urine glucose concentration (HP:0011016)3.59803590
20Milia (HP:0001056)3.56819075
21Abnormality of chloride homeostasis (HP:0011422)3.55044795
22Flat acetabular roof (HP:0003180)3.52188104
23Nausea (HP:0002018)3.47908134
24Xanthomatosis (HP:0000991)3.35099851
25Pili torti (HP:0003777)3.34578745
26Rectal prolapse (HP:0002035)3.34018571
27Villous atrophy (HP:0011473)3.28836175
28Abnormality of small intestinal villus morphology (HP:0011472)3.28836175
29Mildly elevated creatine phosphokinase (HP:0008180)3.21073946
30Steatorrhea (HP:0002570)3.19244709
31Abnormality of glycine metabolism (HP:0010895)3.18678349
32Abnormality of serine family amino acid metabolism (HP:0010894)3.18678349
33Wide cranial sutures (HP:0010537)3.15625286
34Abnormality of aspartate family amino acid metabolism (HP:0010899)3.13994478
35Fat malabsorption (HP:0002630)3.13593809
36Glomerulonephritis (HP:0000099)3.11824264
37Nephrolithiasis (HP:0000787)3.10706584
38Ureteral stenosis (HP:0000071)3.07813128
39Hyperammonemia (HP:0001987)3.06810409
40Autoimmune thrombocytopenia (HP:0001973)3.06276444
41Onycholysis (HP:0001806)3.05379356
42Complement deficiency (HP:0004431)3.02597422
43Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.01145681
44Dehydration (HP:0001944)2.99454466
45Abnormal tarsal ossification (HP:0008369)2.98964803
46Woolly hair (HP:0002224)2.98187401
47Ureteral obstruction (HP:0006000)2.98083171
48Petechiae (HP:0000967)2.90363282
49Poikilocytosis (HP:0004447)2.89509881
50Abnormality of complement system (HP:0005339)2.85514518
51Autoimmune hemolytic anemia (HP:0001890)2.83440630
52Increased purine levels (HP:0004368)2.83156593
53Hyperuricemia (HP:0002149)2.83156593
54Abnormal biliary tract morphology (HP:0012440)2.76287285
55Palpitations (HP:0001962)2.74611640
56Pustule (HP:0200039)2.74423202
57Fragile nails (HP:0001808)2.70441308
58Abnormality of renin-angiotensin system (HP:0000847)2.69156390
59Atrophic scars (HP:0001075)2.67919799
60Abnormality of the gastric mucosa (HP:0004295)2.64778144
61Nephritis (HP:0000123)2.63258065
62Facial shape deformation (HP:0011334)2.62745642
63Potter facies (HP:0002009)2.62745642
64Megaloblastic anemia (HP:0001889)2.61410482
65Abnormal foot bone ossification (HP:0010675)2.61128142
66Posterior subcapsular cataract (HP:0007787)2.60886306
67Epidermoid cyst (HP:0200040)2.60117669
68Decreased circulating renin level (HP:0003351)2.59681633
69Abnormality of purine metabolism (HP:0004352)2.59544671
70Abnormality of the 1st metacarpal (HP:0010009)2.59274836
71Progressive sensorineural hearing impairment (HP:0000408)2.58840502
72Hypophosphatemia (HP:0002148)2.55284548
73Abnormality of nucleobase metabolism (HP:0010932)2.54607323
74Plantar hyperkeratosis (HP:0007556)2.53902450
75Abnormality of the distal phalanx of the thumb (HP:0009617)2.52689410
76Eczematoid dermatitis (HP:0000976)2.50365425
77Cupped ribs (HP:0000887)2.47244988
78Abnormality of pyrimidine metabolism (HP:0004353)2.43834926
79Hypotension (HP:0002615)2.41797150
80Vertebral clefting (HP:0008428)2.40975190
81Abnormality of the vitamin B12 metabolism (HP:0004341)2.40154792
82Micronodular cirrhosis (HP:0001413)2.37521740
83Biliary tract neoplasm (HP:0100574)2.36860160
84Abnormality of sulfur amino acid metabolism (HP:0004339)2.35059765
85Abnormal urine phosphate concentration (HP:0012599)2.34727072
86Enlarged epiphyses (HP:0010580)2.31708820
87Hyperphosphaturia (HP:0003109)2.31269488
88Thrombocytosis (HP:0001894)2.28410805
89Metabolic acidosis (HP:0001942)2.27416530
90Hyperparathyroidism (HP:0000843)2.27362683
91Progressive hearing impairment (HP:0001730)2.26713847
92Hemorrhage of the eye (HP:0011885)2.25207118
93Focal segmental glomerulosclerosis (HP:0000097)2.25097243
94Periodontitis (HP:0000704)2.24543354
95Delayed epiphyseal ossification (HP:0002663)2.24312230
96Microretrognathia (HP:0000308)2.22558804
97Widely patent fontanelles and sutures (HP:0004492)2.21699179
98Abnormality of vitamin B metabolism (HP:0004340)2.18382092
99Increased IgE level (HP:0003212)2.16194935
100Congenital sensorineural hearing impairment (HP:0008527)2.16086807
101Pigmentary retinal degeneration (HP:0001146)2.16022359
102Aortic aneurysm (HP:0004942)2.15317144
103Intrahepatic cholestasis (HP:0001406)2.15226135
104Blepharitis (HP:0000498)2.14304228
105Ventricular fibrillation (HP:0001663)2.12261181
106Syncope (HP:0001279)2.11847175
107Abnormal hair laboratory examination (HP:0003328)2.11162355
108Abnormality of the costochondral junction (HP:0000919)2.10548272
109Thin bony cortex (HP:0002753)2.06266380
110Protuberant abdomen (HP:0001538)2.05423817
111Subcapsular cataract (HP:0000523)2.05205253
112Hyperglycinuria (HP:0003108)2.04224247
113Increased mean platelet volume (HP:0011877)2.03731235
114Fragile skin (HP:0001030)2.03659186
115Flattened epiphyses (HP:0003071)2.03413790
116Bundle branch block (HP:0011710)2.01257706
117Abnormality of monocarboxylic acid metabolism (HP:0010996)1.98875071
118Abnormal platelet volume (HP:0011876)1.97977590
119Gout (HP:0001997)1.97731424
120Reduced antithrombin III activity (HP:0001976)1.97642619
121Myopathic facies (HP:0002058)1.96881962
122Abnormality of carpal bone ossification (HP:0006257)1.96162614
123Neoplasm of the rectum (HP:0100743)1.95996723
124Cerebral palsy (HP:0100021)1.95944013
125Neoplasm of the small intestine (HP:0100833)1.95918097
126Hyperlipoproteinemia (HP:0010980)1.95704000
127Renal tubular acidosis (HP:0001947)1.95535917
128Curly hair (HP:0002212)1.95267384
129Abnormality of magnesium homeostasis (HP:0004921)1.94776731
130Hypolipoproteinemia (HP:0010981)1.93582262
131Deviation of the thumb (HP:0009603)1.91914978
132Fatigue (HP:0012378)1.91785092
133Hoarse voice (HP:0001609)1.91597913
134Hypoplasia of dental enamel (HP:0006297)1.91038993
135Cone-rod dystrophy (HP:0000548)1.91020815
136Proximal placement of thumb (HP:0009623)1.90939543
137Goiter (HP:0000853)1.88652280
138Irritability (HP:0000737)1.87899632
139Ventricular tachycardia (HP:0004756)1.85721771
140Gingivitis (HP:0000230)1.84764560
141Dicarboxylic aciduria (HP:0003215)1.84737438
142Abnormality of dicarboxylic acid metabolism (HP:0010995)1.84737438
143Alkalosis (HP:0001948)1.83433248
144Hyperaldosteronism (HP:0000859)1.82984408
145Uterine neoplasm (HP:0010784)1.82005468
146Cheilitis (HP:0100825)1.80215697
147Glomerulosclerosis (HP:0000096)1.79820831
148Male infertility (HP:0003251)1.79332378
149Abnormality of alkaline phosphatase activity (HP:0004379)1.78054665
150Abnormality of vitamin metabolism (HP:0100508)1.77874524
151Abnormal enzyme/coenzyme activity (HP:0012379)1.77625510
152Abnormal glucose tolerance (HP:0001952)1.76567313
153Pancreatitis (HP:0001733)1.76424641
154Chorioretinal atrophy (HP:0000533)1.75897835
155Prostate neoplasm (HP:0100787)1.73370442
156Abnormal cartilage morphology (HP:0002763)1.73301973
157Skin nodule (HP:0200036)1.70174886
158Patchy hypopigmentation of hair (HP:0011365)1.69862263
159Peripheral demyelination (HP:0011096)1.66849702
160Hypokalemia (HP:0002900)1.65054945
161White forelock (HP:0002211)1.63504090
162Hyperphosphatemia (HP:0002905)1.63452070

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B7.86561405
2FRK6.45789344
3MST45.65140071
4LMTK25.47048130
5MST1R3.78501799
6NUAK13.50759397
7PIK3CA3.14565096
8CASK2.95900010
9PRKG22.75892071
10MAP2K22.63418851
11DMPK2.52746394
12MYLK2.25390405
13TESK12.07260754
14RIPK12.06929200
15OBSCN2.04739920
16NME12.03609694
17EPHA32.03446118
18FGFR42.02613435
19EPHB21.94296661
20MAP3K71.90066612
21PTK61.87274799
22STK241.80008269
23TNIK1.68848628
24GRK61.67567541
25TAOK31.63635312
26MAP3K21.61472847
27EEF2K1.54911447
28EPHA21.51718048
29AKT31.51042241
30MAP3K101.48696165
31RAF11.27872189
32NLK1.25796145
33MATK1.24575581
34PDGFRA1.21408625
35PKN21.16556918
36RIPK41.13640887
37ERN11.11689924
38STK38L1.09475434
39TAOK11.09140187
40EPHA41.09010509
41FLT31.07787614
42MET1.06832460
43TEC0.99866394
44STK100.98361400
45ERBB20.97532111
46SCYL20.94806130
47PAK40.93452451
48MAP2K10.89968472
49LRRK20.86965517
50KSR20.82200736
51LIMK10.81389796
52PRKACG0.79258512
53PRKCI0.78611320
54MAP3K80.78275992
55FER0.76626317
56RET0.76472694
57EPHB10.73410475
58PIM10.71517125
59MAP2K60.71124447
60STK390.70741193
61MAP3K120.68953040
62MUSK0.62658297
63IRAK10.61874269
64PDPK10.60950022
65JAK20.60652544
66PRKAA20.60505072
67JAK10.57918358
68PTK20.57130305
69CDC42BPA0.57085227
70PIK3CG0.57022347
71LATS10.55437761
72PAK20.54680734
73PRPF4B0.53937540
74TBK10.53896682
75KDR0.53312685
76PDK10.52771056
77DDR20.51798669
78ILK0.51555508
79MAPKAPK30.51320488
80PAK10.50664995
81TYK20.50522125
82RPS6KB20.50441058
83PRKCZ0.50047164
84TTK0.48835647
85AURKB0.47840712
86TESK20.45831016
87BMX0.43116283
88ROCK10.42554481
89MAPK110.41586012
90STK30.40863022
91MAP3K10.39967073
92CSK0.38238834
93BMPR20.36658762
94CDK60.35692024
95TRIB30.35592923
96YES10.33025469
97OXSR10.32699532
98MELK0.31163192
99DYRK1B0.30845438
100PRKAA10.29445248
101MAP3K60.27241652
102MAP3K50.27162908
103ABL20.25753582
104MAP4K10.25201242
105SRC0.24877134
106PRKCD0.23808459
107ITK0.23793841
108IKBKE0.22941452
109PIM20.22548341
110IGF1R0.22516661
111TTN0.22445521
112FGFR10.22412583
113FGFR30.21887177
114ICK0.20758759
115MAPKAPK20.20502186
116ROCK20.19811606
117TRPM70.19620604
118CAMK2G0.19509382
119PDK20.19363642
120FYN0.18915728
121CDK190.18386850
122PRKACA0.18169124
123GRK10.18024395
124TGFBR10.17596213
125MAP3K110.16656006
126RPS6KB10.16397967
127PRKCQ0.16189918
128CSNK1A10.15926622
129CAMK2D0.15591818
130MAPK70.15578346
131GRK70.15495335
132PDGFRB0.14951098
133PRKCA0.13590086
134CDK40.13282604
135PRKG10.12203487
136MAP3K30.12083409
137PAK30.10234586

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049754.40849632
2Sulfur metabolism_Homo sapiens_hsa009204.31458579
3Mineral absorption_Homo sapiens_hsa049784.22747809
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.12452963
5Renin-angiotensin system_Homo sapiens_hsa046143.68719311
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006013.26660618
7Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.96443676
8Galactose metabolism_Homo sapiens_hsa000522.66368060
9Caffeine metabolism_Homo sapiens_hsa002322.28681485
10Vitamin digestion and absorption_Homo sapiens_hsa049772.24765421
11Bile secretion_Homo sapiens_hsa049762.17884983
12Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.16189647
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.11967737
14Carbohydrate digestion and absorption_Homo sapiens_hsa049732.09739469
15Starch and sucrose metabolism_Homo sapiens_hsa005002.05321073
16Drug metabolism - other enzymes_Homo sapiens_hsa009832.02706439
17Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.99937557
18Fructose and mannose metabolism_Homo sapiens_hsa000511.92064019
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.86800718
20Histidine metabolism_Homo sapiens_hsa003401.85841600
21Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.82466588
22Protein digestion and absorption_Homo sapiens_hsa049741.81237206
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.73321868
24Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.42270573
25Nitrogen metabolism_Homo sapiens_hsa009101.41878434
26Folate biosynthesis_Homo sapiens_hsa007901.34413617
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.30860538
28Fatty acid degradation_Homo sapiens_hsa000711.16627600
29Pentose and glucuronate interconversions_Homo sapiens_hsa000401.15554262
30Tight junction_Homo sapiens_hsa045301.14637580
31Phenylalanine metabolism_Homo sapiens_hsa003601.08690820
32Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.08486464
33Pancreatic secretion_Homo sapiens_hsa049721.07878941
34Glutathione metabolism_Homo sapiens_hsa004801.07219764
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.06390251
36Tryptophan metabolism_Homo sapiens_hsa003801.04971484
37Adherens junction_Homo sapiens_hsa045201.00077169
38N-Glycan biosynthesis_Homo sapiens_hsa005100.99738516
39Primary bile acid biosynthesis_Homo sapiens_hsa001200.95987556
40Pyruvate metabolism_Homo sapiens_hsa006200.93334525
41Cyanoamino acid metabolism_Homo sapiens_hsa004600.93034566
42Leukocyte transendothelial migration_Homo sapiens_hsa046700.91775820
43Glycerolipid metabolism_Homo sapiens_hsa005610.90644902
44Asthma_Homo sapiens_hsa053100.90184299
45Thyroid hormone synthesis_Homo sapiens_hsa049180.89662621
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.87381627
47Pentose phosphate pathway_Homo sapiens_hsa000300.87326060
48ABC transporters_Homo sapiens_hsa020100.82737280
49Carbon metabolism_Homo sapiens_hsa012000.82639300
50alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.81965092
51Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.80205464
52Salmonella infection_Homo sapiens_hsa051320.80194489
53Staphylococcus aureus infection_Homo sapiens_hsa051500.80098856
54Sphingolipid metabolism_Homo sapiens_hsa006000.79931077
55PPAR signaling pathway_Homo sapiens_hsa033200.76989688
56Arginine and proline metabolism_Homo sapiens_hsa003300.72592061
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70048055
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69060778
59Peroxisome_Homo sapiens_hsa041460.64765277
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63517888
61Tyrosine metabolism_Homo sapiens_hsa003500.59479052
62Thyroid cancer_Homo sapiens_hsa052160.58807120
63Arginine biosynthesis_Homo sapiens_hsa002200.58621108
64Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.58442975
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58226067
66Butanoate metabolism_Homo sapiens_hsa006500.56231572
67Allograft rejection_Homo sapiens_hsa053300.56065704
68Fatty acid biosynthesis_Homo sapiens_hsa000610.56033600
69Autoimmune thyroid disease_Homo sapiens_hsa053200.55574073
70Linoleic acid metabolism_Homo sapiens_hsa005910.54805849
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54349393
72Complement and coagulation cascades_Homo sapiens_hsa046100.52297931
73Toxoplasmosis_Homo sapiens_hsa051450.51864825
74Graft-versus-host disease_Homo sapiens_hsa053320.50569800
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50549713
76African trypanosomiasis_Homo sapiens_hsa051430.49568261
77RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48525936
78Arachidonic acid metabolism_Homo sapiens_hsa005900.47600973
79Hepatitis C_Homo sapiens_hsa051600.47294030
80Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.47262931
81Gastric acid secretion_Homo sapiens_hsa049710.46873267
82Glycerophospholipid metabolism_Homo sapiens_hsa005640.44441015
83Leishmaniasis_Homo sapiens_hsa051400.44431912
84Endometrial cancer_Homo sapiens_hsa052130.42994286
85Biosynthesis of amino acids_Homo sapiens_hsa012300.41381400
86Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39200504
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39015183
88Salivary secretion_Homo sapiens_hsa049700.37239241
89Bladder cancer_Homo sapiens_hsa052190.37095353
90Vibrio cholerae infection_Homo sapiens_hsa051100.35574701
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.34473209
92Type I diabetes mellitus_Homo sapiens_hsa049400.30751154
93Amoebiasis_Homo sapiens_hsa051460.30579744
94beta-Alanine metabolism_Homo sapiens_hsa004100.30468325
95Platelet activation_Homo sapiens_hsa046110.29423743
96Pertussis_Homo sapiens_hsa051330.28907955
97Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28455717
98Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.27886729
99Renin secretion_Homo sapiens_hsa049240.27381090
100Propanoate metabolism_Homo sapiens_hsa006400.27228470
101Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.26924412
102Selenocompound metabolism_Homo sapiens_hsa004500.25682124
103Legionellosis_Homo sapiens_hsa051340.24926770
104Influenza A_Homo sapiens_hsa051640.24276542
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23821792
106Metabolic pathways_Homo sapiens_hsa011000.22950325
107Fatty acid metabolism_Homo sapiens_hsa012120.22812932
108TNF signaling pathway_Homo sapiens_hsa046680.22592283
109Antigen processing and presentation_Homo sapiens_hsa046120.22456888
110Inositol phosphate metabolism_Homo sapiens_hsa005620.21727422
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.20994627
112Small cell lung cancer_Homo sapiens_hsa052220.20013778
113Insulin resistance_Homo sapiens_hsa049310.19693841
114Vascular smooth muscle contraction_Homo sapiens_hsa042700.19565159
115Ether lipid metabolism_Homo sapiens_hsa005650.18354657
116Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.18287669
117Chemical carcinogenesis_Homo sapiens_hsa052040.17967266
118Retinol metabolism_Homo sapiens_hsa008300.17196143
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.17073808
120Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.15174935
121Other glycan degradation_Homo sapiens_hsa005110.14616755
122Central carbon metabolism in cancer_Homo sapiens_hsa052300.12320460
123Cocaine addiction_Homo sapiens_hsa050300.11852977
124Hematopoietic cell lineage_Homo sapiens_hsa046400.11367719
125Glucagon signaling pathway_Homo sapiens_hsa049220.11314354
126Shigellosis_Homo sapiens_hsa051310.10602947
127Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.10541090
128Viral myocarditis_Homo sapiens_hsa054160.09199500
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.08372841
130Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.06695292
131Ovarian steroidogenesis_Homo sapiens_hsa049130.06460324
132Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.05530373

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