ADNP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.31640559
2nuclear pore organization (GO:0006999)5.17684116
3pre-miRNA processing (GO:0031054)4.86499659
4protein localization to kinetochore (GO:0034501)4.51262718
5DNA unwinding involved in DNA replication (GO:0006268)4.47928199
6regulation of posttranscriptional gene silencing (GO:0060147)4.34573877
7regulation of gene silencing by miRNA (GO:0060964)4.34573877
8regulation of gene silencing by RNA (GO:0060966)4.34573877
9negative regulation of histone methylation (GO:0031061)4.26847282
10establishment of integrated proviral latency (GO:0075713)4.24870642
11mitotic nuclear envelope disassembly (GO:0007077)4.18715614
12mitotic sister chromatid cohesion (GO:0007064)4.09410828
13chromatin remodeling at centromere (GO:0031055)4.07877446
14heterochromatin organization (GO:0070828)4.04416239
15DNA strand elongation (GO:0022616)4.03074387
16CENP-A containing nucleosome assembly (GO:0034080)4.00732370
17regulation of translational fidelity (GO:0006450)4.00219239
18membrane disassembly (GO:0030397)3.99411569
19nuclear envelope disassembly (GO:0051081)3.99411569
20regulation of histone H3-K9 methylation (GO:0051570)3.96547285
21DNA replication checkpoint (GO:0000076)3.93764989
22DNA synthesis involved in DNA repair (GO:0000731)3.91828254
23pore complex assembly (GO:0046931)3.90506442
24regulation of RNA export from nucleus (GO:0046831)3.73984003
25regulation of sister chromatid cohesion (GO:0007063)3.65861612
26DNA replication-dependent nucleosome organization (GO:0034723)3.64947279
27DNA replication-dependent nucleosome assembly (GO:0006335)3.64947279
28protein localization to chromosome, centromeric region (GO:0071459)3.64574525
29folic acid-containing compound biosynthetic process (GO:0009396)3.59532098
30DNA topological change (GO:0006265)3.58473892
31DNA duplex unwinding (GO:0032508)3.55527176
32mitotic chromosome condensation (GO:0007076)3.55502310
33DNA geometric change (GO:0032392)3.55346161
34telomere maintenance via semi-conservative replication (GO:0032201)3.55140537
35histone exchange (GO:0043486)3.54636099
36synapsis (GO:0007129)3.50608566
37DNA replication-independent nucleosome organization (GO:0034724)3.50108641
38DNA replication-independent nucleosome assembly (GO:0006336)3.50108641
39regulation of translational termination (GO:0006449)3.49290868
40sister chromatid segregation (GO:0000819)3.48414607
41IMP biosynthetic process (GO:0006188)3.46880822
42negative regulation of chromosome segregation (GO:0051985)3.46675159
43regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.45037522
44dosage compensation (GO:0007549)3.44933142
45negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.39905492
46negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.39905492
47negative regulation of mitotic sister chromatid segregation (GO:0033048)3.39905492
48negative regulation of mitotic sister chromatid separation (GO:2000816)3.39905492
49negative regulation of sister chromatid segregation (GO:0033046)3.39905492
50protein complex localization (GO:0031503)3.39869476
51sister chromatid cohesion (GO:0007062)3.38492399
52double-strand break repair via nonhomologous end joining (GO:0006303)3.37584883
53non-recombinational repair (GO:0000726)3.37584883
54mitotic sister chromatid segregation (GO:0000070)3.36901092
55glucocorticoid receptor signaling pathway (GO:0042921)3.36301510
56chromatin assembly (GO:0031497)3.33855043
57spindle checkpoint (GO:0031577)3.31685208
58DNA ligation (GO:0006266)3.30989216
59mitotic spindle checkpoint (GO:0071174)3.26613050
60regulation of spindle organization (GO:0090224)3.26243556
61kinetochore organization (GO:0051383)3.25929437
62regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.25636369
63regulation of mitotic metaphase/anaphase transition (GO:0030071)3.25636369
64histone H2A monoubiquitination (GO:0035518)3.23961803
65regulation of DNA endoreduplication (GO:0032875)3.23521090
66regulation of mitotic spindle organization (GO:0060236)3.22708422
67regulation of sister chromatid segregation (GO:0033045)3.20895531
68regulation of mitotic sister chromatid separation (GO:0010965)3.20895531
69regulation of mitotic sister chromatid segregation (GO:0033047)3.20895531
70ATP-dependent chromatin remodeling (GO:0043044)3.20643964
71positive regulation of mitotic sister chromatid separation (GO:1901970)3.20502649
72positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.20502649
73positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.20502649
74determination of adult lifespan (GO:0008340)3.19101956
75mitotic metaphase plate congression (GO:0007080)3.18991359
76positive regulation of SMAD protein import into nucleus (GO:0060391)3.17822005
77cellular protein complex localization (GO:0034629)3.17738879
78paraxial mesoderm development (GO:0048339)3.13931825
79positive regulation of chromosome segregation (GO:0051984)3.13911548
80nuclear envelope organization (GO:0006998)3.13642822
81DNA replication initiation (GO:0006270)3.13411957
82IMP metabolic process (GO:0046040)3.13248175
83NLS-bearing protein import into nucleus (GO:0006607)3.12072115
84regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.11992235
85mitotic G2/M transition checkpoint (GO:0044818)3.11925227
86mitotic spindle assembly checkpoint (GO:0007094)3.11786414
87chromosome segregation (GO:0007059)3.10961911
88maturation of SSU-rRNA (GO:0030490)3.09134812
89negative regulation of DNA repair (GO:0045738)3.05828785
90mitotic G1 DNA damage checkpoint (GO:0031571)3.05521923
91negative regulation of histone modification (GO:0031057)3.05430993
92spindle assembly checkpoint (GO:0071173)3.05423444
93gene silencing by RNA (GO:0031047)3.04758472
94telomere maintenance via recombination (GO:0000722)3.04224296
95mitotic recombination (GO:0006312)3.03819620
96peptidyl-arginine omega-N-methylation (GO:0035247)3.00564256
97meiotic chromosome segregation (GO:0045132)2.99504402
98nucleobase biosynthetic process (GO:0046112)2.98632521
99regulation of nucleobase-containing compound transport (GO:0032239)2.97567820
100regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.95952290
101establishment of viral latency (GO:0019043)2.94677128
102metaphase plate congression (GO:0051310)2.93777385
103regulation of gene silencing (GO:0060968)2.93046659
104negative regulation of chromatin modification (GO:1903309)2.92323773
105regulation of SMAD protein import into nucleus (GO:0060390)2.91994070
106chromosome condensation (GO:0030261)2.91662720
107RNA stabilization (GO:0043489)2.89978398
108mRNA stabilization (GO:0048255)2.89978398
109peptidyl-arginine methylation (GO:0018216)2.89596615
110peptidyl-arginine N-methylation (GO:0035246)2.89596615
111spliceosomal tri-snRNP complex assembly (GO:0000244)2.88848281
112histone H4-K12 acetylation (GO:0043983)2.88457578
113regulation of hippo signaling (GO:0035330)2.88172225
114formation of translation preinitiation complex (GO:0001731)2.87612167
115corticosteroid receptor signaling pathway (GO:0031958)2.86996985
116protein localization to chromosome (GO:0034502)2.83261690
117nodal signaling pathway (GO:0038092)2.81688921
118negative regulation of DNA-dependent DNA replication (GO:2000104)2.80119024
119somatic diversification of immune receptors via somatic mutation (GO:0002566)2.79388283
120somatic hypermutation of immunoglobulin genes (GO:0016446)2.79388283
121DNA conformation change (GO:0071103)2.79320791
122ribosomal small subunit assembly (GO:0000028)2.78078287
123regulation of telomere maintenance via telomerase (GO:0032210)2.78054744
124attachment of spindle microtubules to kinetochore (GO:0008608)2.77056848
125negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.76647396
126negative regulation of mitosis (GO:0045839)2.76535575
127negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.75781171
128gene silencing (GO:0016458)2.74391544
129peptidyl-lysine dimethylation (GO:0018027)2.73606787
130DNA strand elongation involved in DNA replication (GO:0006271)2.72771023
131regulation of translation, ncRNA-mediated (GO:0045974)2.72710852
132regulation of DNA damage checkpoint (GO:2000001)2.69811918
133mRNA transport (GO:0051028)2.69484155
134mitotic G1/S transition checkpoint (GO:0044819)2.68859923
135chromatin assembly or disassembly (GO:0006333)2.68579883
136microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.65580357
137nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.65519352
138G1 DNA damage checkpoint (GO:0044783)2.61418120
139trophectodermal cell differentiation (GO:0001829)2.61351614
140regulation of centrosome cycle (GO:0046605)2.60885465
141establishment of apical/basal cell polarity (GO:0035089)2.60873756
142establishment of chromosome localization (GO:0051303)2.60804069
143histone arginine methylation (GO:0034969)2.59780955
144anterior/posterior axis specification, embryo (GO:0008595)2.58649954
145histone H4-K8 acetylation (GO:0043982)2.58198293
146histone H4-K5 acetylation (GO:0043981)2.58198293
147regulation of chromosome segregation (GO:0051983)2.57262302
148regulation of helicase activity (GO:0051095)2.56614683
149spindle assembly involved in mitosis (GO:0090307)2.55348513
150regulation of centriole replication (GO:0046599)2.54767024

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.09398870
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.98437968
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.07148207
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.59466667
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.10592896
6MYC_22102868_ChIP-Seq_BL_Human2.83006970
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.76756536
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.67294792
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.64283220
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.63633146
11KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.55853583
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.45751603
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.39665561
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.37997565
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.29309164
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.25688343
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21273480
18POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.13056303
19KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.10592430
20KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.10592430
21KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.10592430
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.10169320
23E2F1_21310950_ChIP-Seq_MCF-7_Human2.06952531
24MYC_19030024_ChIP-ChIP_MESCs_Mouse2.04229602
25AR_21909140_ChIP-Seq_LNCAP_Human2.04121183
26ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.01648433
27ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.99335976
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.93964369
29SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.91473336
30ELK1_19687146_ChIP-ChIP_HELA_Human1.91070747
31NELFA_20434984_ChIP-Seq_ESCs_Mouse1.86292550
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.83435226
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.71918267
34NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.71662097
35NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67349912
36DCP1A_22483619_ChIP-Seq_HELA_Human1.66242251
37SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.66043852
38MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64505433
39PADI4_21655091_ChIP-ChIP_MCF-7_Human1.61324718
40STAT3_1855785_ChIP-Seq_MESCs_Mouse1.60891575
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58328324
42POU5F1_16153702_ChIP-ChIP_HESCs_Human1.56319368
43* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.55739100
44XRN2_22483619_ChIP-Seq_HELA_Human1.54347144
45NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.54038477
46PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.53417821
47TCF7_22412390_ChIP-Seq_EML_Mouse1.52593887
48MYC_18358816_ChIP-ChIP_MESCs_Mouse1.51881892
49HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.49503312
50TCF3_18692474_ChIP-Seq_MEFs_Mouse1.49340224
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.47094420
52ETS1_20019798_ChIP-Seq_JURKAT_Human1.46805762
53SOX2_16153702_ChIP-ChIP_HESCs_Human1.46500675
54VDR_21846776_ChIP-Seq_THP-1_Human1.44184808
55NANOG_16153702_ChIP-ChIP_HESCs_Human1.44119973
56HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.44085709
57TCF3_18692474_ChIP-Seq_MESCs_Mouse1.43673560
58CIITA_25753668_ChIP-Seq_RAJI_Human1.43356279
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41602461
60ESR1_15608294_ChIP-ChIP_MCF-7_Human1.40666328
61THAP11_20581084_ChIP-Seq_MESCs_Mouse1.40514532
62KLF4_18555785_ChIP-Seq_MESCs_Mouse1.39827722
63* VDR_23849224_ChIP-Seq_CD4+_Human1.39482342
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.38365138
65HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36099601
66KDM5A_27292631_Chip-Seq_BREAST_Human1.33314664
67DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.33194063
68KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.32227231
69ZFP281_27345836_Chip-Seq_ESCs_Mouse1.31138873
70ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.30854396
71NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.30661297
72* TFEB_21752829_ChIP-Seq_HELA_Human1.30519299
73SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.30300207
74DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.29297620
75ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29132491
76ZFP281_18757296_ChIP-ChIP_E14_Mouse1.29102373
77NANOG_21062744_ChIP-ChIP_HESCs_Human1.28595347
78TP63_19390658_ChIP-ChIP_HaCaT_Human1.27164489
79KDM2B_26808549_Chip-Seq_DND41_Human1.27162224
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.26547256
81KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.26382200
82YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.23853702
83HIF1A_21447827_ChIP-Seq_MCF-7_Human1.23225663
84TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23219978
85STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.22770258
86JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.22250049
87* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.20718083
88ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.19348689
89MYC_18940864_ChIP-ChIP_HL60_Human1.18953890
90POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13069318
91TTF2_22483619_ChIP-Seq_HELA_Human1.11862367
92CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.11446396
93PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11413900
94CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11203246
95PKCTHETA_26484144_Chip-Seq_BREAST_Human1.10885009
96TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10058999
97HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09351487
98SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.07572701
99* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.06987778
100ERG_20887958_ChIP-Seq_HPC-7_Mouse1.06952017
101KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.06123336
102ELK3_25401928_ChIP-Seq_HUVEC_Human1.05524696
103EWS_26573619_Chip-Seq_HEK293_Human1.05486319
104ATF3_27146783_Chip-Seq_COLON_Human1.03745363
105TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.03647640
106ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02525754
107BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02471876
108CHD1_26751641_Chip-Seq_LNCaP_Human0.99925807
109E2F1_18555785_ChIP-Seq_MESCs_Mouse0.99865724
110FUS_26573619_Chip-Seq_HEK293_Human0.99786685
111KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98786654
112DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.98324453
113SOX2_18692474_ChIP-Seq_MESCs_Mouse0.97855379
114SOX17_20123909_ChIP-Seq_XEN_Mouse0.96559148
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96479045
116UTX_26944678_Chip-Seq_JUKART_Human0.95004858
117FOXP3_21729870_ChIP-Seq_TREG_Human0.94687592
118CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.94302097
119E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.94236254
120MAF_26560356_Chip-Seq_TH1_Human0.92025881
121NOTCH1_21737748_ChIP-Seq_TLL_Human0.91635009
122NCOR1_26117541_ChIP-Seq_K562_Human0.91211711
123POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90976621
124GABP_19822575_ChIP-Seq_HepG2_Human0.89469056
125FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.89337402
126TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88775738
127GATA1_26923725_Chip-Seq_HPCs_Mouse0.88232143
128SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.87457988
129TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.87290667
130HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.87169266
131SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.83814509
132WT1_19549856_ChIP-ChIP_CCG9911_Human0.79697330
133YY1_21170310_ChIP-Seq_MESCs_Mouse0.79081810

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.68683190
2MP0004957_abnormal_blastocyst_morpholog3.05843674
3MP0003111_abnormal_nucleus_morphology3.05271913
4MP0010094_abnormal_chromosome_stability3.03718590
5MP0003941_abnormal_skin_development3.02852717
6MP0003705_abnormal_hypodermis_morpholog3.00410645
7MP0005076_abnormal_cell_differentiation2.98517339
8MP0003077_abnormal_cell_cycle2.82228035
9MP0008057_abnormal_DNA_replication2.72053547
10MP0003693_abnormal_embryo_hatching2.65533338
11MP0003123_paternal_imprinting2.64929461
12MP0010307_abnormal_tumor_latency2.31069908
13MP0000350_abnormal_cell_proliferation2.25079012
14MP0001730_embryonic_growth_arrest2.22859036
15MP0006292_abnormal_olfactory_placode2.11148410
16MP0002084_abnormal_developmental_patter2.07877614
17MP0004197_abnormal_fetal_growth/weight/2.07626070
18MP0008007_abnormal_cellular_replicative2.01456330
19MP0003566_abnormal_cell_adhesion1.98334682
20MP0005380_embryogenesis_phenotype1.98130493
21MP0001672_abnormal_embryogenesis/_devel1.98130493
22MP0010234_abnormal_vibrissa_follicle1.95048127
23MP0003121_genomic_imprinting1.94805119
24MP0008877_abnormal_DNA_methylation1.94113601
25MP0002086_abnormal_extraembryonic_tissu1.90928098
26MP0003984_embryonic_growth_retardation1.89323134
27MP0000537_abnormal_urethra_morphology1.87450657
28MP0002088_abnormal_embryonic_growth/wei1.86842641
29MP0002085_abnormal_embryonic_tissue1.82406635
30MP0003567_abnormal_fetal_cardiomyocyte1.82277195
31MP0009278_abnormal_bone_marrow1.81486420
32MP0001697_abnormal_embryo_size1.81141678
33MP0004808_abnormal_hematopoietic_stem1.76479095
34MP0003890_abnormal_embryonic-extraembry1.74059645
35MP0005623_abnormal_meninges_morphology1.72436443
36MP0010030_abnormal_orbit_morphology1.61639628
37MP0002080_prenatal_lethality1.58168626
38MP0009379_abnormal_foot_pigmentation1.53867724
39MP0003119_abnormal_digestive_system1.53799601
40MP0003136_yellow_coat_color1.51383271
41MP0002396_abnormal_hematopoietic_system1.50876015
42MP0003718_maternal_effect1.50394495
43MP0008058_abnormal_DNA_repair1.45361521
44MP0000566_synostosis1.44102313
45MP0005023_abnormal_wound_healing1.43375863
46MP0001849_ear_inflammation1.41446775
47MP0004264_abnormal_extraembryonic_tissu1.40181242
48MP0001293_anophthalmia1.35741989
49MP0008932_abnormal_embryonic_tissue1.35014455
50MP0000569_abnormal_digit_pigmentation1.35002899
51MP0006054_spinal_hemorrhage1.34423073
52MP0002009_preneoplasia1.33278577
53MP0002877_abnormal_melanocyte_morpholog1.32515324
54MP0009053_abnormal_anal_canal1.31721187
55MP0003283_abnormal_digestive_organ1.31247852
56MP0000733_abnormal_muscle_development1.30911792
57MP0000428_abnormal_craniofacial_morphol1.30635229
58MP0005397_hematopoietic_system_phenotyp1.28015233
59MP0001545_abnormal_hematopoietic_system1.28015233
60MP0008995_early_reproductive_senescence1.25205027
61MP0000490_abnormal_crypts_of1.25147323
62MP0009697_abnormal_copulation1.24096167
63MP0002653_abnormal_ependyma_morphology1.22936376
64MP0002254_reproductive_system_inflammat1.22506494
65MP0002925_abnormal_cardiovascular_devel1.21502331
66MP0001915_intracranial_hemorrhage1.19011545
67MP0001929_abnormal_gametogenesis1.16540897
68MP0009703_decreased_birth_body1.16118988
69MP0002233_abnormal_nose_morphology1.14579247
70MP0003091_abnormal_cell_migration1.13134464
71MP0000579_abnormal_nail_morphology1.12408784
72MP0002938_white_spotting1.08213735
73MP0002019_abnormal_tumor_incidence1.07734789
74MP0001346_abnormal_lacrimal_gland1.07154745
75MP0001188_hyperpigmentation1.07016997
76MP0003315_abnormal_perineum_morphology1.04624626
77MP0003943_abnormal_hepatobiliary_system1.04614448
78MP0003300_gastrointestinal_ulcer1.04580228
79MP0004133_heterotaxia1.01959299
80MP0000313_abnormal_cell_death1.00797370
81MP0000653_abnormal_sex_gland0.99017212
82MP0004185_abnormal_adipocyte_glucose0.96435986
83MP0003935_abnormal_craniofacial_develop0.96096215
84MP0003937_abnormal_limbs/digits/tail_de0.95142385
85MP0003787_abnormal_imprinting0.94975131
86MP0000432_abnormal_head_morphology0.94056844
87MP0000703_abnormal_thymus_morphology0.93374222
88MP0002111_abnormal_tail_morphology0.93027635
89MP0008770_decreased_survivor_rate0.92983664
90MP0005621_abnormal_cell_physiology0.92968447
91MP0002092_abnormal_eye_morphology0.92948923
92MP0003115_abnormal_respiratory_system0.92550154
93MP0003448_altered_tumor_morphology0.92169465
94MP0009672_abnormal_birth_weight0.91143575
95MP0000516_abnormal_urinary_system0.89966502
96MP0005367_renal/urinary_system_phenotyp0.89966502
97MP0005248_abnormal_Harderian_gland0.88737048
98MP0004233_abnormal_muscle_weight0.86458106
99MP0003303_peritoneal_inflammation0.85243283
100MP0003861_abnormal_nervous_system0.85214628
101MP0002697_abnormal_eye_size0.83030208
102MP0005384_cellular_phenotype0.80504526
103MP0002210_abnormal_sex_determination0.79287589
104MP0003786_premature_aging0.78668379
105MP0000266_abnormal_heart_morphology0.78468218
106MP0001145_abnormal_male_reproductive0.78433740
107MP0003385_abnormal_body_wall0.77903525
108MP0008961_abnormal_basal_metabolism0.77885492
109MP0002160_abnormal_reproductive_system0.77725392
110MP0001340_abnormal_eyelid_morphology0.77359034
111MP0001348_abnormal_lacrimal_gland0.76933875
112MP0005187_abnormal_penis_morphology0.76782212
113MP0002081_perinatal_lethality0.76781678
114MP0010630_abnormal_cardiac_muscle0.75596244
115MP0008438_abnormal_cutaneous_collagen0.75408770
116MP0003453_abnormal_keratinocyte_physiol0.75061278
117MP0001119_abnormal_female_reproductive0.74651070
118MP0002932_abnormal_joint_morphology0.74390854
119MP0000858_altered_metastatic_potential0.73424250
120MP0003698_abnormal_male_reproductive0.71974343
121MP0003699_abnormal_female_reproductive0.71762001
122MP0009250_abnormal_appendicular_skeleto0.71680321
123MP0002796_impaired_skin_barrier0.71210817
124MP0001286_abnormal_eye_development0.70296771
125MP0003279_aneurysm0.69855157
126MP0003942_abnormal_urinary_system0.68282827
127MP0002751_abnormal_autonomic_nervous0.67508308
128MP0002398_abnormal_bone_marrow0.67186136
129MP0002116_abnormal_craniofacial_bone0.67171250
130MP0004272_abnormal_basement_membrane0.66476761
131MP0010678_abnormal_skin_adnexa0.66211636
132MP0003755_abnormal_palate_morphology0.66135291
133MP0000049_abnormal_middle_ear0.66100776
134MP0003221_abnormal_cardiomyocyte_apopto0.65952346
135MP0002114_abnormal_axial_skeleton0.64694342
136MP0000383_abnormal_hair_follicle0.64594954
137MP0002161_abnormal_fertility/fecundity0.64024457
138MP0005391_vision/eye_phenotype0.63988424
139MP0000762_abnormal_tongue_morphology0.63613839

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.07423723
2Astrocytoma (HP:0009592)3.51192555
3Abnormality of the astrocytes (HP:0100707)3.51192555
4Reticulocytopenia (HP:0001896)3.50243659
5Meckel diverticulum (HP:0002245)3.36108615
6Nephroblastoma (Wilms tumor) (HP:0002667)3.29946348
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.28615361
8Short 4th metacarpal (HP:0010044)3.28615361
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.26458033
10Abnormality of the ileum (HP:0001549)3.22310731
11Abnormality of chromosome stability (HP:0003220)3.21835664
12Embryonal renal neoplasm (HP:0011794)3.15915781
13Medulloblastoma (HP:0002885)3.13206234
14Abnormality of the preputium (HP:0100587)2.94744995
15Neoplasm of the oral cavity (HP:0100649)2.91832267
16Colon cancer (HP:0003003)2.90260948
17Abnormality of the labia minora (HP:0012880)2.88949798
18Birth length less than 3rd percentile (HP:0003561)2.74196350
19Selective tooth agenesis (HP:0001592)2.71833236
20Glioma (HP:0009733)2.69508753
21Abnormal lung lobation (HP:0002101)2.66764597
22Increased nuchal translucency (HP:0010880)2.63945405
23Duodenal stenosis (HP:0100867)2.61771431
24Small intestinal stenosis (HP:0012848)2.61771431
25Missing ribs (HP:0000921)2.58675873
26Rhabdomyosarcoma (HP:0002859)2.55986960
27Deviation of the thumb (HP:0009603)2.51673028
28Neoplasm of striated muscle (HP:0009728)2.48338420
29Volvulus (HP:0002580)2.47439008
30Basal cell carcinoma (HP:0002671)2.45559833
31Short middle phalanx of the 5th finger (HP:0004220)2.45188107
32Duplication of thumb phalanx (HP:0009942)2.44865467
33Hyperacusis (HP:0010780)2.44813121
34Agnosia (HP:0010524)2.41663717
35Proximal placement of thumb (HP:0009623)2.40326428
36Renal duplication (HP:0000075)2.39382400
37Septo-optic dysplasia (HP:0100842)2.38892884
38Deep philtrum (HP:0002002)2.36841567
39Abnormality of the duodenum (HP:0002246)2.34830666
40Aplasia involving forearm bones (HP:0009822)2.33356118
41Absent forearm bone (HP:0003953)2.33356118
42High anterior hairline (HP:0009890)2.31466137
43Abnormality of the 4th metacarpal (HP:0010012)2.30911557
44Protrusio acetabuli (HP:0003179)2.30799027
45Aplasia/Hypoplasia of the sternum (HP:0006714)2.30000518
46Heterotopia (HP:0002282)2.29625373
47Gastrointestinal carcinoma (HP:0002672)2.26844091
48Malignant gastrointestinal tract tumors (HP:0006749)2.26844091
49Urethral obstruction (HP:0000796)2.25532228
50Broad thumb (HP:0011304)2.25382961
51Broad palm (HP:0001169)2.18972561
52Triphalangeal thumb (HP:0001199)2.18331557
53Facial hemangioma (HP:0000329)2.16054252
54Supernumerary ribs (HP:0005815)2.13105545
55Genu recurvatum (HP:0002816)2.12896036
56Shallow orbits (HP:0000586)2.11287767
57Abnormality of the septum pellucidum (HP:0007375)2.11165676
58Biliary tract neoplasm (HP:0100574)2.10120739
59Short humerus (HP:0005792)2.09789331
60Long eyelashes (HP:0000527)2.09744605
61Aplasia/hypoplasia of the humerus (HP:0006507)2.09365689
62Fibroma (HP:0010614)2.08263640
63Fibrous tissue neoplasm (HP:0012316)2.07839804
64Ankle contracture (HP:0006466)2.07448831
65Cerebral aneurysm (HP:0004944)2.06608435
66Bowel diverticulosis (HP:0005222)2.05395730
67Choanal atresia (HP:0000453)2.04849587
68Pancreatic islet-cell hyperplasia (HP:0004510)2.04178043
69Angiofibromas (HP:0010615)2.03747350
70Adenoma sebaceum (HP:0009720)2.03747350
71Facial cleft (HP:0002006)2.03546794
72Partial duplication of thumb phalanx (HP:0009944)2.01669812
73Rib fusion (HP:0000902)2.01256360
74Esophageal atresia (HP:0002032)2.00997378
75Sloping forehead (HP:0000340)2.00304270
76Abnormality of the fingertips (HP:0001211)2.00065725
77Aplasia/Hypoplasia of the sacrum (HP:0008517)1.99070212
78Supernumerary bones of the axial skeleton (HP:0009144)1.98972649
79Overriding aorta (HP:0002623)1.98618492
80Ectopic kidney (HP:0000086)1.94817166
81Horseshoe kidney (HP:0000085)1.94343931
82Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.94221970
83Progressive external ophthalmoplegia (HP:0000590)1.94163158
84Subacute progressive viral hepatitis (HP:0006572)1.92954406
85Abnormal hair whorl (HP:0010721)1.89122187
86Broad phalanges of the hand (HP:0009768)1.89115768
87Embryonal neoplasm (HP:0002898)1.89091143
88Cafe-au-lait spot (HP:0000957)1.88786625
89Abnormality of DNA repair (HP:0003254)1.88227998
90Annular pancreas (HP:0001734)1.87431170
91Capillary hemangiomas (HP:0005306)1.86727009
92Amaurosis fugax (HP:0100576)1.85421585
93Short thumb (HP:0009778)1.84433198
94Abnormality of the lower motor neuron (HP:0002366)1.84401491
95Myelodysplasia (HP:0002863)1.83565922
96Acute lymphatic leukemia (HP:0006721)1.83494322
97Chromsome breakage (HP:0040012)1.83095891
98Macroorchidism (HP:0000053)1.83090837
99Short phalanx of the thumb (HP:0009660)1.81611037
100Arteriovenous malformation (HP:0100026)1.81193063
101Microglossia (HP:0000171)1.80851012
102Renovascular hypertension (HP:0100817)1.80643814
103Absent thumb (HP:0009777)1.80281047
104Acute myeloid leukemia (HP:0004808)1.80264066
105Absent septum pellucidum (HP:0001331)1.79695294
106Hepatoblastoma (HP:0002884)1.78302007
107Spastic diplegia (HP:0001264)1.78208300
108Carpal bone hypoplasia (HP:0001498)1.78065480
109Anal stenosis (HP:0002025)1.77326842
110High pitched voice (HP:0001620)1.77279840
111Sandal gap (HP:0001852)1.75735637
112Abnormality of the distal phalanx of the thumb (HP:0009617)1.75648792
113Clubbing of toes (HP:0100760)1.75558572
114Fused cervical vertebrae (HP:0002949)1.74753751
115Abnormality of chromosome segregation (HP:0002916)1.74656854
116Pseudobulbar signs (HP:0002200)1.74388952
117Increased density of long bones (HP:0006392)1.74297662
118Pointed chin (HP:0000307)1.74129373
119Duplicated collecting system (HP:0000081)1.73870463
120Partial duplication of the phalanx of hand (HP:0009999)1.73839209
121Abnormality of the lacrimal duct (HP:0011481)1.73697676
122Intestinal polyp (HP:0005266)1.72891874
123Dislocated radial head (HP:0003083)1.72665496
124Vertebral fusion (HP:0002948)1.72503771
12511 pairs of ribs (HP:0000878)1.72398883
126Spinal muscular atrophy (HP:0007269)1.72384136
127Short middle phalanx of finger (HP:0005819)1.72176726
128Abnormal number of incisors (HP:0011064)1.72133928
129Oligodactyly (hands) (HP:0001180)1.71922359
130Abnormality of cochlea (HP:0000375)1.70749287
131Absent radius (HP:0003974)1.70712577
132Skin tags (HP:0010609)1.70090603
133Bifid tongue (HP:0010297)1.69577100
134Trigonocephaly (HP:0000243)1.69419358
135Broad finger (HP:0001500)1.69240247
136Patellar aplasia (HP:0006443)1.68151577
137Ulnar bowing (HP:0003031)1.67901889
138Abnormality of the diencephalon (HP:0010662)1.67467867
139Atresia of the external auditory canal (HP:0000413)1.67166704
140Overlapping toe (HP:0001845)1.66065765
141Neoplasm of the colon (HP:0100273)1.65879961
142Cervical subluxation (HP:0003308)1.65730190
143Broad phalanx (HP:0006009)1.65594942
144Elfin facies (HP:0004428)1.65429871
145Multiple enchondromatosis (HP:0005701)1.64894304
146Abnormality of the nasolacrimal system (HP:0000614)1.64655891
147Hypoplastic labia majora (HP:0000059)1.64632123
148Hand muscle atrophy (HP:0009130)1.64592276
149Abnormality of the calcaneus (HP:0008364)1.64261979
150Skull defect (HP:0001362)1.63646532
151Metaphyseal cupping (HP:0003021)1.63426529
152Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.63208557
153Short 1st metacarpal (HP:0010034)1.63208557
154Gastrointestinal atresia (HP:0002589)1.63186322
155Stenosis of the external auditory canal (HP:0000402)1.62402130
156Prominent nose (HP:0000448)1.62319962
157Intestinal polyposis (HP:0200008)1.62260668
158Uterine neoplasm (HP:0010784)1.62131352
159Abnormality of homocysteine metabolism (HP:0010919)1.61759096
160Homocystinuria (HP:0002156)1.61759096
161Cortical dysplasia (HP:0002539)1.61067401
162Chromosomal breakage induced by crosslinking agents (HP:0003221)1.60558875
163Abnormality of the radial head (HP:0003995)1.60278767
164Abnormality of the carotid arteries (HP:0005344)1.60005982

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.84458310
2CDC73.75938496
3EEF2K3.08203648
4PKN22.87742721
5WEE12.60591671
6TRIB32.53916754
7MAP3K102.46378778
8BRD42.44197448
9TAF12.44155775
10NEK22.43589774
11PLK42.39122380
12TSSK62.24724515
13TRIM282.19421776
14EPHA22.05916905
15SCYL21.94234790
16STK101.89282562
17TTK1.85030136
18ALK1.82987318
19NEK11.82211369
20ZAK1.80271607
21LATS11.78806005
22PBK1.73283691
23RPS6KB21.73235712
24EIF2AK31.71033022
25TNIK1.63423755
26PAK41.57975183
27PDGFRA1.50518193
28CDK71.47503085
29CDK41.46116670
30MTOR1.39830966
31RIPK11.36328984
32LATS21.35102472
33CDK61.34979192
34VRK11.34153822
35PASK1.31399132
36TTN1.30848350
37MAP3K81.29842582
38CHEK11.29690831
39LRRK21.26473869
40PLK11.24356671
41ATR1.23952892
42MELK1.22883503
43SMG11.22570388
44VRK21.21067449
45CHEK21.20752325
46STK38L1.19177747
47ICK1.18554089
48DDR21.17397617
49TGFBR11.15255848
50ERBB41.12705027
51CASK1.12277445
52STK31.12124365
53PLK31.07816128
54NLK1.06315277
55TYRO31.02954590
56EIF2AK11.02288380
57BUB11.01613914
58FLT30.98031055
59DYRK30.97761619
60EIF2AK20.97139496
61PTK60.96859619
62KSR10.96300782
63MST40.96039060
64ACVR1B0.94269227
65AURKB0.92390001
66CDK20.91786436
67CDK90.90710069
68PAK20.90584776
69MAP3K90.90010067
70BRSK20.89607654
71ATM0.89521866
72SRPK10.86774564
73RPS6KA40.81186520
74GRK60.80635047
75STK240.80299879
76STK40.77871980
77PIM10.76069646
78FGFR10.72677074
79CAMK1D0.69042504
80MKNK20.68899044
81KSR20.66087821
82MKNK10.65868512
83PNCK0.65770584
84PDGFRB0.65643008
85CDK10.64544562
86BMX0.64450000
87TLK10.59859393
88CSNK1D0.57834145
89PTK20.56365410
90RAF10.56115826
91NUAK10.55251231
92DMPK0.54446083
93TAOK10.54175165
94YES10.53676796
95BCR0.51629962
96FGFR30.49506712
97CDK190.49128785
98CSNK1E0.48240043
99PRKD30.47953293
100IRAK20.47583083
101AKT20.47083445
102PRKDC0.46910045
103PAK60.45574739
104CLK10.45470324
105PAK10.44141331
106CDK30.43227506
107MAPK10.43046112
108MAPK140.42498821
109RET0.42018675
110BRAF0.41967841
111PRKCI0.41430392
112AURKA0.41209581
113RPS6KA10.40196249
114WNK30.39545961
115FGFR20.38706122
116MAPK100.38150514
117AKT10.36462141
118PRPF4B0.35791399
119GSK3B0.35702405
120SIK20.35663729
121BMPR1B0.35482270
122ERN10.35008303
123BRSK10.34467266
124MARK30.33411707
125DYRK20.33372430
126AKT30.32999780
127CSNK2A20.32844071
128IRAK10.30849765
129MET0.30807109
130CSNK2A10.30554992
131CAMK1G0.29600947
132CHUK0.29213989
133ILK0.28919586

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.92452062
2Mismatch repair_Homo sapiens_hsa034302.90877588
3RNA transport_Homo sapiens_hsa030132.59527535
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.50480178
5Cell cycle_Homo sapiens_hsa041102.32239114
6Spliceosome_Homo sapiens_hsa030402.19011036
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.12967181
8One carbon pool by folate_Homo sapiens_hsa006702.05544615
9mRNA surveillance pathway_Homo sapiens_hsa030152.00141633
10Base excision repair_Homo sapiens_hsa034101.71183916
11MicroRNAs in cancer_Homo sapiens_hsa052061.68906774
12mTOR signaling pathway_Homo sapiens_hsa041501.58668942
13Nucleotide excision repair_Homo sapiens_hsa034201.56196314
14p53 signaling pathway_Homo sapiens_hsa041151.53129774
15Proteasome_Homo sapiens_hsa030501.52984089
16Colorectal cancer_Homo sapiens_hsa052101.47562405
17Small cell lung cancer_Homo sapiens_hsa052221.47115516
18Chronic myeloid leukemia_Homo sapiens_hsa052201.46605607
19Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.45700054
20Hippo signaling pathway_Homo sapiens_hsa043901.39012532
21Viral carcinogenesis_Homo sapiens_hsa052031.39009259
22Adherens junction_Homo sapiens_hsa045201.34380944
23RNA degradation_Homo sapiens_hsa030181.33170003
24Fanconi anemia pathway_Homo sapiens_hsa034601.33138406
25Cysteine and methionine metabolism_Homo sapiens_hsa002701.30264361
26Homologous recombination_Homo sapiens_hsa034401.30252979
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.29602841
28Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.27193561
29Oocyte meiosis_Homo sapiens_hsa041141.26895979
30Notch signaling pathway_Homo sapiens_hsa043301.25233011
31HTLV-I infection_Homo sapiens_hsa051661.18060502
32Basal cell carcinoma_Homo sapiens_hsa052171.18028540
33Non-small cell lung cancer_Homo sapiens_hsa052231.15870361
34Thyroid hormone signaling pathway_Homo sapiens_hsa049191.13676514
35Protein export_Homo sapiens_hsa030601.12342312
36Proteoglycans in cancer_Homo sapiens_hsa052051.12322685
37Steroid biosynthesis_Homo sapiens_hsa001001.11929366
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.11759725
39Thyroid cancer_Homo sapiens_hsa052161.11626685
40TGF-beta signaling pathway_Homo sapiens_hsa043501.11061559
41Central carbon metabolism in cancer_Homo sapiens_hsa052301.10904664
42Systemic lupus erythematosus_Homo sapiens_hsa053221.09275824
43Endometrial cancer_Homo sapiens_hsa052131.07300507
44Antigen processing and presentation_Homo sapiens_hsa046120.97294031
45Epstein-Barr virus infection_Homo sapiens_hsa051690.97039534
46Focal adhesion_Homo sapiens_hsa045100.96903013
47Bladder cancer_Homo sapiens_hsa052190.96675463
48Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96507106
49Pancreatic cancer_Homo sapiens_hsa052120.94519929
50Non-homologous end-joining_Homo sapiens_hsa034500.92494142
51Neurotrophin signaling pathway_Homo sapiens_hsa047220.91301582
52Glioma_Homo sapiens_hsa052140.90763855
53Pathways in cancer_Homo sapiens_hsa052000.89772568
54Hedgehog signaling pathway_Homo sapiens_hsa043400.88404964
55Herpes simplex infection_Homo sapiens_hsa051680.86757465
56Hepatitis B_Homo sapiens_hsa051610.85627949
57Acute myeloid leukemia_Homo sapiens_hsa052210.85089123
58Dorso-ventral axis formation_Homo sapiens_hsa043200.85007102
59Prostate cancer_Homo sapiens_hsa052150.83481702
60Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82426416
61Wnt signaling pathway_Homo sapiens_hsa043100.82289621
62VEGF signaling pathway_Homo sapiens_hsa043700.82018319
63Viral myocarditis_Homo sapiens_hsa054160.80426152
64AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79971488
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.79607611
66HIF-1 signaling pathway_Homo sapiens_hsa040660.79118578
67Vitamin B6 metabolism_Homo sapiens_hsa007500.78583556
68Renal cell carcinoma_Homo sapiens_hsa052110.78495791
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.77673639
70Regulation of actin cytoskeleton_Homo sapiens_hsa048100.72261533
71Leukocyte transendothelial migration_Homo sapiens_hsa046700.71932277
72Basal transcription factors_Homo sapiens_hsa030220.71740866
73Estrogen signaling pathway_Homo sapiens_hsa049150.71180051
74Tight junction_Homo sapiens_hsa045300.70866020
75RNA polymerase_Homo sapiens_hsa030200.70527399
76Alcoholism_Homo sapiens_hsa050340.70485266
77Lysine degradation_Homo sapiens_hsa003100.68914150
78FoxO signaling pathway_Homo sapiens_hsa040680.68658348
79Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.67734480
80Pyruvate metabolism_Homo sapiens_hsa006200.67482909
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67045514
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66959255
83Purine metabolism_Homo sapiens_hsa002300.66144141
84ECM-receptor interaction_Homo sapiens_hsa045120.64611310
85B cell receptor signaling pathway_Homo sapiens_hsa046620.64477653
86Apoptosis_Homo sapiens_hsa042100.63328779
87Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62617268
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60521593
89Melanoma_Homo sapiens_hsa052180.59440203
90Rap1 signaling pathway_Homo sapiens_hsa040150.59087035
91Shigellosis_Homo sapiens_hsa051310.59028601
92Toxoplasmosis_Homo sapiens_hsa051450.58713646
93Ribosome_Homo sapiens_hsa030100.56349180
94PI3K-Akt signaling pathway_Homo sapiens_hsa041510.55693773
95ErbB signaling pathway_Homo sapiens_hsa040120.55409130
96Inositol phosphate metabolism_Homo sapiens_hsa005620.54338510
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53280148
98AMPK signaling pathway_Homo sapiens_hsa041520.52983158
99Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52219678
100Platelet activation_Homo sapiens_hsa046110.52066528
101Amoebiasis_Homo sapiens_hsa051460.51889978
102Pyrimidine metabolism_Homo sapiens_hsa002400.51513283
103Biosynthesis of amino acids_Homo sapiens_hsa012300.50634267
104T cell receptor signaling pathway_Homo sapiens_hsa046600.50418432
105Huntingtons disease_Homo sapiens_hsa050160.50105676
106Selenocompound metabolism_Homo sapiens_hsa004500.49564397
107MAPK signaling pathway_Homo sapiens_hsa040100.48782191
108Insulin signaling pathway_Homo sapiens_hsa049100.48757308
109Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.48163829
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47481465
111Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.46796875
112Prolactin signaling pathway_Homo sapiens_hsa049170.46512248
113Legionellosis_Homo sapiens_hsa051340.45071953
114Propanoate metabolism_Homo sapiens_hsa006400.44392471
115N-Glycan biosynthesis_Homo sapiens_hsa005100.43019750
116Melanogenesis_Homo sapiens_hsa049160.31533956
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30917744
118Circadian rhythm_Homo sapiens_hsa047100.29883270
119Fatty acid biosynthesis_Homo sapiens_hsa000610.22933752
120Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.20560807
121Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.18984621
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.18199052
123Carbon metabolism_Homo sapiens_hsa012000.17632753
1242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.17054102
125Vitamin digestion and absorption_Homo sapiens_hsa049770.16854920
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.15761482
127Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.12660701
128Measles_Homo sapiens_hsa051620.08513097

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