ADPRM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1signal peptide processing (GO:0006465)4.69067606
2purine nucleotide salvage (GO:0032261)4.33342857
3adenosine metabolic process (GO:0046085)4.15400568
4regulation of activation of Janus kinase activity (GO:0010533)4.03515466
5purine-containing compound salvage (GO:0043101)3.96217315
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.92998152
7histone mRNA catabolic process (GO:0071044)3.92592810
8mitochondrial DNA replication (GO:0006264)3.86740482
9preassembly of GPI anchor in ER membrane (GO:0016254)3.68908427
10aldehyde catabolic process (GO:0046185)3.63382098
11nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.62170610
12DNA deamination (GO:0045006)3.59824298
13reactive oxygen species biosynthetic process (GO:1903409)3.50535700
14mannosylation (GO:0097502)3.47846745
15protein-cofactor linkage (GO:0018065)3.47294928
16respiratory chain complex IV assembly (GO:0008535)3.46064395
17exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.45904454
18peptidyl-histidine modification (GO:0018202)3.45686534
19daunorubicin metabolic process (GO:0044597)3.43626810
20polyketide metabolic process (GO:0030638)3.43626810
21doxorubicin metabolic process (GO:0044598)3.43626810
22ATP synthesis coupled proton transport (GO:0015986)3.42302762
23energy coupled proton transport, down electrochemical gradient (GO:0015985)3.42302762
24low-density lipoprotein particle remodeling (GO:0034374)3.38208938
25sequestering of actin monomers (GO:0042989)3.34714361
26protein neddylation (GO:0045116)3.33763502
27cytochrome complex assembly (GO:0017004)3.33743652
28hydrogen peroxide biosynthetic process (GO:0050665)3.30792554
29platelet dense granule organization (GO:0060155)3.28429955
30respiratory burst (GO:0045730)3.24403792
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.24208539
32antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.24208539
33antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.18877281
34neutrophil activation involved in immune response (GO:0002283)3.17667067
35antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.17330488
36mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.13120674
37histone mRNA metabolic process (GO:0008334)3.11572840
38L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.08709052
39cellular response to interferon-beta (GO:0035458)3.07655579
40GPI anchor biosynthetic process (GO:0006506)3.06960428
41peptide catabolic process (GO:0043171)3.06276921
42protein K11-linked deubiquitination (GO:0035871)3.04550169
43antigen processing and presentation of endogenous antigen (GO:0019883)3.04323934
44C-terminal protein lipidation (GO:0006501)3.02501439
45aggressive behavior (GO:0002118)3.02461025
46organelle disassembly (GO:1903008)3.02396561
47phosphorylated carbohydrate dephosphorylation (GO:0046838)3.01487314
48inositol phosphate dephosphorylation (GO:0046855)3.01487314
49DNA double-strand break processing (GO:0000729)3.01457561
50antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.99067828
51response to interferon-beta (GO:0035456)2.98791611
52water-soluble vitamin biosynthetic process (GO:0042364)2.98344125
53positive regulation of gamma-delta T cell activation (GO:0046645)2.97314763
54RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.97003996
55oxygen transport (GO:0015671)2.92800179
56regulation of cholesterol esterification (GO:0010872)2.91714423
57respiratory electron transport chain (GO:0022904)2.91416280
58transepithelial transport (GO:0070633)2.91369965
59killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.90267293
60disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.90267293
61electron transport chain (GO:0022900)2.90142637
62deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.90133822
63positive regulation of vasculogenesis (GO:2001214)2.89562745
64ribonucleoprotein complex disassembly (GO:0032988)2.88229309
65GPI anchor metabolic process (GO:0006505)2.87716945
66organelle membrane fusion (GO:0090174)2.87556425
67positive regulation of granulocyte differentiation (GO:0030854)2.86849061
68purine deoxyribonucleotide metabolic process (GO:0009151)2.86293947
69maturation of 5.8S rRNA (GO:0000460)2.84519173
70purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.81935549
71regulation of cilium movement (GO:0003352)2.80130442
72positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.79259351
73regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.78370020
74cellular response to zinc ion (GO:0071294)2.77118606
75rRNA modification (GO:0000154)2.76661526
76protein complex biogenesis (GO:0070271)2.75553750
77tryptophan metabolic process (GO:0006568)2.74695629
78positive regulation of humoral immune response (GO:0002922)2.74451304
79inositol phosphate catabolic process (GO:0071545)2.74173513
80epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.71564601
81positive regulation of alpha-beta T cell proliferation (GO:0046641)2.70965096
82interferon-gamma production (GO:0032609)2.69614206
83mitochondrial respiratory chain complex I assembly (GO:0032981)2.68049075
84NADH dehydrogenase complex assembly (GO:0010257)2.68049075
85mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.68049075
86purine deoxyribonucleotide catabolic process (GO:0009155)2.66560958
87positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.65779928
88cellular biogenic amine catabolic process (GO:0042402)2.65426054
89amine catabolic process (GO:0009310)2.65426054
90amino acid salvage (GO:0043102)2.65206229
91L-methionine salvage (GO:0071267)2.65206229
92L-methionine biosynthetic process (GO:0071265)2.65206229
93mitochondrial respiratory chain complex assembly (GO:0033108)2.64067514
94deoxyribonucleotide catabolic process (GO:0009264)2.63597505
95AMP metabolic process (GO:0046033)2.63017640
96C-terminal protein amino acid modification (GO:0018410)2.62157619
97xenobiotic catabolic process (GO:0042178)2.61599544
98indole-containing compound catabolic process (GO:0042436)2.58749935
99indolalkylamine catabolic process (GO:0046218)2.58749935
100tryptophan catabolic process (GO:0006569)2.58749935
101negative regulation of meiosis (GO:0045835)2.58035033
102cullin deneddylation (GO:0010388)2.57823367
103autophagic vacuole fusion (GO:0000046)2.57594519
104response to nitrosative stress (GO:0051409)2.56752539
105protein deneddylation (GO:0000338)2.56505302
106regulation of alpha-beta T cell proliferation (GO:0046640)2.56259775
107NAD biosynthetic process (GO:0009435)2.55575549
108negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.55366704
109aromatic amino acid family catabolic process (GO:0009074)2.54707218
110deoxyribonucleotide metabolic process (GO:0009262)2.54328818
111regulation of B cell apoptotic process (GO:0002902)2.53569709
112positive regulation of B cell mediated immunity (GO:0002714)2.51482355
113positive regulation of immunoglobulin mediated immune response (GO:0002891)2.51482355
114nucleoside salvage (GO:0043174)2.51043587
115negative regulation of growth of symbiont in host (GO:0044130)2.50401257
116negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.50401257
117modulation of growth of symbiont involved in interaction with host (GO:0044144)2.50401257
118regulation of growth of symbiont in host (GO:0044126)2.50401257
119deoxyribose phosphate catabolic process (GO:0046386)2.50343194
120superoxide anion generation (GO:0042554)2.49877586
121hydrogen ion transmembrane transport (GO:1902600)2.48985847
122type I interferon signaling pathway (GO:0060337)2.48984936
123cellular response to type I interferon (GO:0071357)2.48984936
124pyrimidine nucleotide catabolic process (GO:0006244)2.48936350
125response to type I interferon (GO:0034340)2.48899888
126DNA demethylation (GO:0080111)2.47144876
127antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.47124855
128DNA dealkylation (GO:0035510)2.46509302
129pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.44635099
130rRNA methylation (GO:0031167)2.43025041
131DNA integration (GO:0015074)2.42903663
132production of molecular mediator involved in inflammatory response (GO:0002532)2.41887590
133histone H2A acetylation (GO:0043968)2.41520717
134pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.41319094
135killing of cells of other organism (GO:0031640)2.40179615
136disruption of cells of other organism (GO:0044364)2.40179615
137metallo-sulfur cluster assembly (GO:0031163)2.39469458
138iron-sulfur cluster assembly (GO:0016226)2.39469458
139prenylation (GO:0097354)2.39217947
140protein prenylation (GO:0018342)2.39217947
141DNA catabolic process, exonucleolytic (GO:0000738)2.38649423
142base-excision repair, AP site formation (GO:0006285)2.38597054
143proton transport (GO:0015992)2.38341486
144regulation of cellular amino acid metabolic process (GO:0006521)2.38300537
145regulation of lipoprotein particle clearance (GO:0010984)2.38156254
146L-phenylalanine catabolic process (GO:0006559)2.37958149
147erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.37958149
148hydrogen transport (GO:0006818)2.37204059
149GMP metabolic process (GO:0046037)2.36734348
150positive regulation of isotype switching (GO:0045830)2.36468943
151anterograde synaptic vesicle transport (GO:0048490)2.36341885
152branched-chain amino acid catabolic process (GO:0009083)2.36288560
153regulation of RIG-I signaling pathway (GO:0039535)2.35465005
154neutrophil activation (GO:0042119)2.35349621
155viral mRNA export from host cell nucleus (GO:0046784)2.33568025
156granulocyte activation (GO:0036230)2.33437934
157T cell migration (GO:0072678)2.33364394
158regulation of inflammatory response to antigenic stimulus (GO:0002861)2.31101373
159RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.30567662
160tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.30567662
161DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.30452706
162indolalkylamine metabolic process (GO:0006586)2.29975453
163positive regulation of DNA recombination (GO:0045911)2.29956112
164response to peptidoglycan (GO:0032494)2.29493370
165negative regulation of myeloid cell apoptotic process (GO:0033033)2.27971720
166negative T cell selection (GO:0043383)2.27906002
167deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.27754122
168positive regulation of interferon-alpha production (GO:0032727)2.26145771
1692-deoxyribonucleotide metabolic process (GO:0009394)2.25873062
170proteasome assembly (GO:0043248)2.25767021
171intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.24932812
172signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.24932812
173deoxyribose phosphate metabolic process (GO:0019692)2.24216453
1742-deoxyribonucleotide biosynthetic process (GO:0009265)2.23495058
175deoxyribose phosphate biosynthetic process (GO:0046385)2.23495058
176ribosomal small subunit assembly (GO:0000028)2.23305616

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.20636260
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.93102540
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.76750692
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.68123802
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.48753025
6IRF8_21731497_ChIP-ChIP_J774_Mouse3.47748349
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.97833288
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.84994625
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.80057584
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.79283815
11CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.73515459
12CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.65826716
13GATA1_22025678_ChIP-Seq_K562_Human2.53597018
14EGR1_23403033_ChIP-Seq_LIVER_Mouse2.52458751
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.44630265
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.42952880
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.42302202
18ZNF274_21170338_ChIP-Seq_K562_Hela2.40829588
19SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.40824486
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.39809011
21PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.37766073
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.36320619
23POU3F2_20337985_ChIP-ChIP_501MEL_Human2.35351784
24E2F7_22180533_ChIP-Seq_HELA_Human2.26899053
25FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.26351911
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.24288659
27STAT4_19710469_ChIP-ChIP_TH1__Mouse2.20889149
28VDR_23849224_ChIP-Seq_CD4+_Human2.12940201
29EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.08445973
30FUS_26573619_Chip-Seq_HEK293_Human2.04869295
31ELK1_19687146_ChIP-ChIP_HELA_Human2.02846248
32HOXB4_20404135_ChIP-ChIP_EML_Mouse2.02627798
33CREB1_15753290_ChIP-ChIP_HEK293T_Human2.00300585
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98456586
35MYC_18555785_ChIP-Seq_MESCs_Mouse1.97743774
36EWS_26573619_Chip-Seq_HEK293_Human1.94471107
37MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.93391305
38PCGF2_27294783_Chip-Seq_ESCs_Mouse1.86585777
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.85598643
40ETS1_20019798_ChIP-Seq_JURKAT_Human1.84240490
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.84148393
42DCP1A_22483619_ChIP-Seq_HELA_Human1.82757693
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81297857
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77700452
45CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.72102786
46MYC_18358816_ChIP-ChIP_MESCs_Mouse1.70729568
47* SPI1_23547873_ChIP-Seq_NB4_Human1.70376916
48E2F1_18555785_ChIP-Seq_MESCs_Mouse1.69939882
49CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.68414884
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.66954534
51FOXP3_21729870_ChIP-Seq_TREG_Human1.65640490
52MYC_18940864_ChIP-ChIP_HL60_Human1.65309356
53VDR_22108803_ChIP-Seq_LS180_Human1.64610729
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.61780448
55ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59473060
56IRF8_27001747_Chip-Seq_BMDM_Mouse1.58439579
57IGF1R_20145208_ChIP-Seq_DFB_Human1.55047193
58STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.54029853
59MYC_19030024_ChIP-ChIP_MESCs_Mouse1.53219915
60CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.51424606
61STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.49873187
62SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.49676735
63IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48774315
64CBP_20019798_ChIP-Seq_JUKART_Human1.48774315
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.48774163
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.48032102
67GBX2_23144817_ChIP-Seq_PC3_Human1.47935401
68P300_19829295_ChIP-Seq_ESCs_Human1.47229022
69TP53_22573176_ChIP-Seq_HFKS_Human1.43867096
70MYB_21317192_ChIP-Seq_ERMYB_Mouse1.43777535
71NELFA_20434984_ChIP-Seq_ESCs_Mouse1.42028105
72ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.40129870
73SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40030381
74NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39487447
75TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37418505
76TAF15_26573619_Chip-Seq_HEK293_Human1.37109181
77RXR_22158963_ChIP-Seq_LIVER_Mouse1.35971241
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.34903195
79GABP_19822575_ChIP-Seq_HepG2_Human1.31089174
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30048641
81STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.29991351
82MYB_26560356_Chip-Seq_TH2_Human1.28671371
83PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27640555
84NFE2_27457419_Chip-Seq_LIVER_Mouse1.27419935
85EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26802972
86SMAD_19615063_ChIP-ChIP_OVARY_Human1.25582802
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.25373894
88BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.25260794
89SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22587849
90PPARA_22158963_ChIP-Seq_LIVER_Mouse1.22571766
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.22235701
92TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21808484
93THAP11_20581084_ChIP-Seq_MESCs_Mouse1.21803580
94FOXA1_27270436_Chip-Seq_PROSTATE_Human1.19048693
95FOXA1_25329375_ChIP-Seq_VCAP_Human1.19048693
96FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18278151
97RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.18132772
98PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16639518
99RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.16326023
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16297636
101CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16018806
102POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.13655740
103XRN2_22483619_ChIP-Seq_HELA_Human1.11216816
104SOX2_19829295_ChIP-Seq_ESCs_Human1.10597983
105NANOG_19829295_ChIP-Seq_ESCs_Human1.10597983
106NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10189759
107YY1_21170310_ChIP-Seq_MESCs_Mouse1.10074210
108CRX_20693478_ChIP-Seq_RETINA_Mouse1.09849751
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.08216597
110IRF1_19129219_ChIP-ChIP_H3396_Human1.08108231
111LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07031942
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.06827503
113GATA3_26560356_Chip-Seq_TH2_Human1.05239009
114MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.05182734
115ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03725438
116ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.03229636
117SALL4_22934838_ChIP-ChIP_CD34+_Human1.02805782
118CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.01218612
119E2F4_17652178_ChIP-ChIP_JURKAT_Human1.00543268
120PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.00311701
121AR_20517297_ChIP-Seq_VCAP_Human0.99951927
122MYB_26560356_Chip-Seq_TH1_Human0.99604206
123FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.99114668
124ER_23166858_ChIP-Seq_MCF-7_Human0.97766244
125NCOR_22424771_ChIP-Seq_293T_Human0.96754529
126SALL1_21062744_ChIP-ChIP_HESCs_Human0.96531063
127HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.95687947
128FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.95248907
129CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95210519
130CTBP1_25329375_ChIP-Seq_LNCAP_Human0.94532396
131ELK1_22589737_ChIP-Seq_MCF10A_Human0.94375627
132UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93605833
133FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.92966735
134CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92813675
135TFEB_21752829_ChIP-Seq_HELA_Human0.92732595
136AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92648091
137GATA3_21878914_ChIP-Seq_MCF-7_Human0.91358537
138CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.91301371
139STAT3_18555785_Chip-Seq_ESCs_Mouse0.91093707
140RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.90019800
141MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90013751
142LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.89713842
143CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.89576858
144P53_22387025_ChIP-Seq_ESCs_Mouse0.89277860
145SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.88941811
146NANOG_18555785_Chip-Seq_ESCs_Mouse0.88913663
147PU.1_20513432_ChIP-Seq_Bcells_Mouse0.88086894
148EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.88028906
149CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87824536
150SUZ12_18555785_Chip-Seq_ESCs_Mouse0.87581803
151BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86319841
152FLI1_27457419_Chip-Seq_LIVER_Mouse0.85689182
153LXR_22158963_ChIP-Seq_LIVER_Mouse0.85633608
154Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.83493201

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.42654953
2MP0003806_abnormal_nucleotide_metabolis3.40728045
3MP0009785_altered_susceptibility_to3.28459092
4MP0002139_abnormal_hepatobiliary_system3.05133405
5MP0003724_increased_susceptibility_to3.03365630
6MP0005671_abnormal_response_to2.94841574
7MP0003436_decreased_susceptibility_to2.85567043
8MP0002148_abnormal_hypersensitivity_rea2.69957380
9MP0003300_gastrointestinal_ulcer2.69151745
10MP0000685_abnormal_immune_system2.42216193
11MP0003186_abnormal_redox_activity2.37384699
12MP0005085_abnormal_gallbladder_physiolo2.36592161
13MP0005000_abnormal_immune_tolerance2.36243022
14MP0005360_urolithiasis2.35605041
15MP0002822_catalepsy2.34353211
16MP0005025_abnormal_response_to2.30352692
17MP0002419_abnormal_innate_immunity2.24172420
18MP0006054_spinal_hemorrhage2.24162821
19MP0008875_abnormal_xenobiotic_pharmacok2.24110660
20MP0008877_abnormal_DNA_methylation2.22770227
21MP0005365_abnormal_bile_salt2.19393899
22MP0002928_abnormal_bile_duct2.17833122
23MP0001790_abnormal_immune_system2.17091531
24MP0005387_immune_system_phenotype2.17091531
25MP0006082_CNS_inflammation2.09388472
26MP0001800_abnormal_humoral_immune2.09079562
27MP0005220_abnormal_exocrine_pancreas2.08240893
28MP0009697_abnormal_copulation2.01005359
29MP0002723_abnormal_immune_serum1.95393493
30MP0001853_heart_inflammation1.94376847
31MP0002452_abnormal_antigen_presenting1.88397085
32MP0005084_abnormal_gallbladder_morpholo1.83159086
33MP0002420_abnormal_adaptive_immunity1.81338067
34MP0001819_abnormal_immune_cell1.80248239
35MP0002837_dystrophic_cardiac_calcinosis1.79722230
36MP0009764_decreased_sensitivity_to1.77696780
37MP0004782_abnormal_surfactant_physiolog1.76436881
38MP0002138_abnormal_hepatobiliary_system1.75910574
39MP0005397_hematopoietic_system_phenotyp1.73879783
40MP0001545_abnormal_hematopoietic_system1.73879783
41MP0002876_abnormal_thyroid_physiology1.71009662
42MP0003763_abnormal_thymus_physiology1.65002393
43MP0003183_abnormal_peptide_metabolism1.58759177
44MP0009333_abnormal_splenocyte_physiolog1.58239887
45MP0002102_abnormal_ear_morphology1.57266857
46MP0001986_abnormal_taste_sensitivity1.57236584
47MP0001845_abnormal_inflammatory_respons1.56470139
48MP0006036_abnormal_mitochondrial_physio1.55919923
49MP0003693_abnormal_embryo_hatching1.54054765
50MP0005083_abnormal_biliary_tract1.51576438
51MP0008469_abnormal_protein_level1.50650502
52MP0001764_abnormal_homeostasis1.49935750
53MP0005253_abnormal_eye_physiology1.44041906
54MP0001984_abnormal_olfaction1.43930896
55MP0003786_premature_aging1.42913308
56MP0005408_hypopigmentation1.41989054
57MP0008995_early_reproductive_senescence1.41562323
58MP0005075_abnormal_melanosome_morpholog1.41399941
59MP0005464_abnormal_platelet_physiology1.41188807
60MP0000716_abnormal_immune_system1.38183077
61MP0002398_abnormal_bone_marrow1.38101532
62MP0005646_abnormal_pituitary_gland1.37869956
63MP0010155_abnormal_intestine_physiology1.37782810
64MP0004145_abnormal_muscle_electrophysio1.36667579
65MP0006072_abnormal_retinal_apoptosis1.36061458
66MP0004147_increased_porphyrin_level1.34600349
67MP0008872_abnormal_physiological_respon1.32800583
68MP0002405_respiratory_system_inflammati1.32542467
69MP0002132_abnormal_respiratory_system1.31698038
70MP0005410_abnormal_fertilization1.30200749
71MP0001533_abnormal_skeleton_physiology1.30127503
72MP0003283_abnormal_digestive_organ1.26004618
73MP0009278_abnormal_bone_marrow1.23642094
74MP0010329_abnormal_lipoprotein_level1.22979858
75MP0005379_endocrine/exocrine_gland_phen1.22789752
76MP0002006_tumorigenesis1.22579356
77MP0000689_abnormal_spleen_morphology1.21632272
78MP0000858_altered_metastatic_potential1.19636064
79MP0010386_abnormal_urinary_bladder1.18733796
80MP0006292_abnormal_olfactory_placode1.17835550
81MP0005645_abnormal_hypothalamus_physiol1.15978272
82MP0003195_calcinosis1.15591825
83MP0005332_abnormal_amino_acid1.14680429
84MP0002429_abnormal_blood_cell1.14462466
85MP0002254_reproductive_system_inflammat1.13948673
86MP0002693_abnormal_pancreas_physiology1.13066612
87MP0003787_abnormal_imprinting1.12944234
88MP0003191_abnormal_cellular_cholesterol1.12020591
89MP0002163_abnormal_gland_morphology1.10802322
90MP0004142_abnormal_muscle_tone1.09916125
91MP0002722_abnormal_immune_system1.09566749
92MP0005367_renal/urinary_system_phenotyp1.09280722
93MP0000516_abnormal_urinary_system1.09280722
94MP0000372_irregular_coat_pigmentation1.09012622
95MP0003075_altered_response_to1.08292246
96MP0005584_abnormal_enzyme/coenzyme_acti1.08146395
97MP0002277_abnormal_respiratory_mucosa1.07723147
98MP0005058_abnormal_lysosome_morphology1.07517937
99MP0003943_abnormal_hepatobiliary_system1.06857233
100MP0009763_increased_sensitivity_to1.06747638
101MP0001968_abnormal_touch/_nociception1.06621325
102MP0003646_muscle_fatigue1.06522722
103MP0000609_abnormal_liver_physiology1.05867413
104MP0002166_altered_tumor_susceptibility1.04134242
105MP0004808_abnormal_hematopoietic_stem0.97934548
106MP0000015_abnormal_ear_pigmentation0.97503190
107MP0002933_joint_inflammation0.97134908
108MP0005319_abnormal_enzyme/_coenzyme0.97001119
109MP0008058_abnormal_DNA_repair0.96961110
110MP0005166_decreased_susceptibility_to0.95855185
111MP0002396_abnormal_hematopoietic_system0.94517447
112MP0001666_abnormal_nutrient_absorption0.94244860
113MP0004133_heterotaxia0.93839539
114MP0000465_gastrointestinal_hemorrhage0.91392909
115MP0003252_abnormal_bile_duct0.89357617
116MP0003866_abnormal_defecation0.89279918
117MP0002736_abnormal_nociception_after0.89171643
118MP0006276_abnormal_autonomic_nervous0.88464707
119MP0009643_abnormal_urine_homeostasis0.88450662
120MP0004043_abnormal_pH_regulation0.88099354
121MP0005395_other_phenotype0.83868213
122MP0005389_reproductive_system_phenotype0.83752147
123MP0009765_abnormal_xenobiotic_induced0.83561448
124MP0003656_abnormal_erythrocyte_physiolo0.83247793
125MP0001529_abnormal_vocalization0.82536777
126MP0000230_abnormal_systemic_arterial0.82037541
127MP0005551_abnormal_eye_electrophysiolog0.81938324
128MP0006035_abnormal_mitochondrial_morpho0.79970390
129MP0001905_abnormal_dopamine_level0.79564996
130MP0002638_abnormal_pupillary_reflex0.79539885
131MP0005376_homeostasis/metabolism_phenot0.79428281
132MP0001119_abnormal_female_reproductive0.78566818
133MP0000613_abnormal_salivary_gland0.78475127
134MP0008873_increased_physiological_sensi0.78038854
135MP0003718_maternal_effect0.77302468
136MP0003011_delayed_dark_adaptation0.76765268
137MP0008057_abnormal_DNA_replication0.76098966
138MP0005266_abnormal_metabolism0.75282277
139MP0001919_abnormal_reproductive_system0.73473154
140MP0008007_abnormal_cellular_replicative0.72717021
141MP0004019_abnormal_vitamin_homeostasis0.72135277
142MP0005636_abnormal_mineral_homeostasis0.72075711
143MP0000598_abnormal_liver_morphology0.70831851
144MP0003121_genomic_imprinting0.69658503
145MP0001944_abnormal_pancreas_morphology0.69142428

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.70760225
2Recurrent gram-negative bacterial infections (HP:0005420)3.64118119
3Methylmalonic acidemia (HP:0002912)3.59024184
4Recurrent abscess formation (HP:0002722)3.53154739
5Abnormality of the renal cortex (HP:0011035)3.38703568
6Recurrent bacterial skin infections (HP:0005406)3.34880216
7Pancreatic cysts (HP:0001737)3.33590836
8Elevated erythrocyte sedimentation rate (HP:0003565)3.21329592
9Acute necrotizing encephalopathy (HP:0006965)3.16926040
10Abnormality of aromatic amino acid family metabolism (HP:0004338)3.08453590
11Mitochondrial inheritance (HP:0001427)3.08199073
12Prolonged partial thromboplastin time (HP:0003645)3.03163869
13Hypothermia (HP:0002045)3.02021252
14Hepatic necrosis (HP:0002605)2.94351189
15Acute encephalopathy (HP:0006846)2.89612655
16Increased CSF lactate (HP:0002490)2.88628489
17Ileus (HP:0002595)2.88467934
18Hepatocellular necrosis (HP:0001404)2.87554136
19Abnormal mitochondria in muscle tissue (HP:0008316)2.86185981
20Methylmalonic aciduria (HP:0012120)2.85063369
21Increased IgM level (HP:0003496)2.79319530
22Medial flaring of the eyebrow (HP:0010747)2.78571947
23Myositis (HP:0100614)2.74190152
24Autoimmune thrombocytopenia (HP:0001973)2.71833282
25Hypobetalipoproteinemia (HP:0003563)2.71149200
26Degeneration of anterior horn cells (HP:0002398)2.67643579
27Abnormality of the anterior horn cell (HP:0006802)2.67643579
28Hypokalemic alkalosis (HP:0001949)2.65087324
29Abnormality of the heme biosynthetic pathway (HP:0010472)2.64863559
30Increased hepatocellular lipid droplets (HP:0006565)2.60957170
31Aplastic anemia (HP:0001915)2.58411124
32Abnormality of macrophages (HP:0004311)2.58280200
33Progressive macrocephaly (HP:0004481)2.57588976
34Lipid accumulation in hepatocytes (HP:0006561)2.56317415
35Renal Fanconi syndrome (HP:0001994)2.55427720
36Increased intramyocellular lipid droplets (HP:0012240)2.54766768
37Mediastinal lymphadenopathy (HP:0100721)2.54232108
38Abnormality of renal resorption (HP:0011038)2.52951212
39Abnormality of midbrain morphology (HP:0002418)2.50629997
40Molar tooth sign on MRI (HP:0002419)2.50629997
41Type I transferrin isoform profile (HP:0003642)2.49822423
42Joint swelling (HP:0001386)2.49103498
43Metabolic alkalosis (HP:0200114)2.45973566
44Exocrine pancreatic insufficiency (HP:0001738)2.45953846
45Abnormality of the renal medulla (HP:0100957)2.45096798
46Abnormal hemoglobin (HP:0011902)2.44440018
47Optic neuritis (HP:0100653)2.40189657
48Retrobulbar optic neuritis (HP:0100654)2.40189657
49Hypoglycemic coma (HP:0001325)2.40112954
50Thrombocytosis (HP:0001894)2.39887092
51Generalized aminoaciduria (HP:0002909)2.39794903
52Cerebral edema (HP:0002181)2.38846255
53Reduced antithrombin III activity (HP:0001976)2.38527735
54Dyschromatopsia (HP:0007641)2.36625939
55Abnormality of the common coagulation pathway (HP:0010990)2.34962164
56Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.34628014
57Abnormal hair whorl (HP:0010721)2.34294142
58Exertional dyspnea (HP:0002875)2.31419598
59Intrahepatic cholestasis (HP:0001406)2.31357968
60Abnormality of methionine metabolism (HP:0010901)2.30590356
61Joint hemorrhage (HP:0005261)2.29946316
62Abnormality of monocarboxylic acid metabolism (HP:0010996)2.26494119
63Abnormality of T cell number (HP:0011839)2.26464437
64Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.25572451
65Decreased electroretinogram (ERG) amplitude (HP:0000654)2.25440812
66Rectal prolapse (HP:0002035)2.24515698
67Dry hair (HP:0011359)2.23773158
68Decreased activity of mitochondrial respiratory chain (HP:0008972)2.23752074
69Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.23752074
70Vasculitis (HP:0002633)2.23724899
71Orchitis (HP:0100796)2.23635097
72Increased muscle lipid content (HP:0009058)2.22771383
73Nephronophthisis (HP:0000090)2.20218866
74Vacuolated lymphocytes (HP:0001922)2.19538603
75Azoospermia (HP:0000027)2.18180261
76Increased serum lactate (HP:0002151)2.17074635
77Obstructive lung disease (HP:0006536)2.16191241
78Chronic obstructive pulmonary disease (HP:0006510)2.16191241
79Abnormality of pyrimidine metabolism (HP:0004353)2.15964922
80Decreased central vision (HP:0007663)2.14984779
81Pancreatic fibrosis (HP:0100732)2.14492258
82Abnormality of chloride homeostasis (HP:0011422)2.12971686
833-Methylglutaconic aciduria (HP:0003535)2.12968752
84Respiratory failure (HP:0002878)2.12541858
85Opisthotonus (HP:0002179)2.12424792
86Tongue fasciculations (HP:0001308)2.11702576
87Recurrent pneumonia (HP:0006532)2.11473933
88Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.10819022
89Abnormality of the intrinsic pathway (HP:0010989)2.09279367
90Hyperglycinemia (HP:0002154)2.08648121
91Nausea (HP:0002018)2.06928578
92Abnormality of vitamin B metabolism (HP:0004340)2.06257483
93Abnormal spermatogenesis (HP:0008669)2.04934854
94Abnormality of the right ventricle (HP:0001707)2.04928593
95Glycosuria (HP:0003076)2.04211296
96Abnormality of urine glucose concentration (HP:0011016)2.04211296
97Decreased circulating renin level (HP:0003351)2.02479974
98IgM deficiency (HP:0002850)2.02369931
99Recurrent fungal infections (HP:0002841)2.02188068
100Fat malabsorption (HP:0002630)2.01654494
101Lactic acidosis (HP:0003128)2.01563372
102Renal cortical cysts (HP:0000803)2.01347189
103Abnormality of the vitamin B12 metabolism (HP:0004341)2.01089787
104T lymphocytopenia (HP:0005403)2.00556880
105Meningitis (HP:0001287)2.00438225
106Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.99251634
107Abnormal protein N-linked glycosylation (HP:0012347)1.99251634
108Abnormal protein glycosylation (HP:0012346)1.99251634
109Abnormal glycosylation (HP:0012345)1.99251634
110Steatorrhea (HP:0002570)1.97793216
111Recurrent skin infections (HP:0001581)1.97735278
112Aplasia/hypoplasia of the uterus (HP:0008684)1.97711274
113Eosinophilia (HP:0001880)1.97374269
114Hyperbilirubinemia (HP:0002904)1.96984456
115Hypoglycemic seizures (HP:0002173)1.96367449
116Abnormality of dicarboxylic acid metabolism (HP:0010995)1.96206153
117Dicarboxylic aciduria (HP:0003215)1.96206153
118Type 2 muscle fiber atrophy (HP:0003554)1.95693185
119Insulin-resistant diabetes mellitus (HP:0000831)1.95524937
120Neuroendocrine neoplasm (HP:0100634)1.95428000
121Stomatitis (HP:0010280)1.95362848
122Exercise intolerance (HP:0003546)1.95282139
123Optic disc pallor (HP:0000543)1.94659696
124Gingivitis (HP:0000230)1.94604242
125Nephrogenic diabetes insipidus (HP:0009806)1.94052908
126Gastrointestinal infarctions (HP:0005244)1.93239475
127Granulocytopenia (HP:0001913)1.92892836
128Congenital primary aphakia (HP:0007707)1.92308904
129True hermaphroditism (HP:0010459)1.91327693
130Abnormality of fatty-acid metabolism (HP:0004359)1.90228356
131Basal ganglia calcification (HP:0002135)1.89665116
132Abnormal biliary tract morphology (HP:0012440)1.89298460
133Renal tubular dysfunction (HP:0000124)1.89113545
134Widely spaced teeth (HP:0000687)1.89080776
135Limb hypertonia (HP:0002509)1.88277141
136Abnormality of aspartate family amino acid metabolism (HP:0010899)1.88056339
137Abnormality of T cells (HP:0002843)1.87217108
138CNS demyelination (HP:0007305)1.86927033
139Congenital hepatic fibrosis (HP:0002612)1.86485966
140Purpura (HP:0000979)1.85415870
141Abnormality of glutamine family amino acid metabolism (HP:0010902)1.84676417
142Microvesicular hepatic steatosis (HP:0001414)1.83282226
143Lethargy (HP:0001254)1.82659950
144Polyuria (HP:0000103)1.82604221
145Flat capital femoral epiphysis (HP:0003370)1.82542382
146Male infertility (HP:0003251)1.82459141
147Recurrent viral infections (HP:0004429)1.81985720
148Facial diplegia (HP:0001349)1.80448701
149Cystic liver disease (HP:0006706)1.78954063
150Abnormal biliary tract physiology (HP:0012439)1.78799175
151Bile duct proliferation (HP:0001408)1.78799175
152Gait imbalance (HP:0002141)1.78241961
153Agnosia (HP:0010524)1.77138466
154Hypoplasia of the uterus (HP:0000013)1.76587421
155IgG deficiency (HP:0004315)1.76193944
156Alveolar cell carcinoma (HP:0006519)1.75955876
157Constricted visual fields (HP:0001133)1.74347109
158Metaphyseal dysplasia (HP:0100255)1.74210560
159Muscle fibrillation (HP:0010546)1.73195410
160Abnormality of B cell number (HP:0010975)1.70779309
161Abnormality of serum amino acid levels (HP:0003112)1.70631505

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LMTK26.61033605
2MAP3K143.75375854
3TXK3.40973957
4TRIM283.06331838
5VRK22.92321728
6MAP3K122.74994342
7IRAK42.68440933
8STK162.66962166
9ACVR1B2.63285138
10NUAK12.61109035
11IRAK32.36028286
12MAP4K12.19973357
13EIF2AK32.18235335
14MST42.18008586
15BMPR21.96713946
16BMPR1B1.77861236
17TYK21.72714555
18NME21.70856626
19NEK61.70365106
20SIK31.70204021
21PBK1.69805544
22EIF2AK11.69196457
23PRKG21.65957879
24STK391.60195074
25INSRR1.60004686
26TEC1.57977185
27PIM21.54307740
28IKBKB1.53330043
29WNK31.52886690
30JAK31.50816735
31IKBKE1.49696956
32ZAP701.49587936
33TBK11.45553171
34PLK41.44816831
35ITK1.40540061
36VRK11.34201411
37STK241.33898268
38PINK11.29664943
39STK38L1.25970960
40CDK81.25351357
41MYLK1.23213248
42SYK1.19478797
43KDR1.17644258
44TSSK61.12986446
45STK101.12446834
46MAP3K41.09539151
47GRK71.09078667
48WNK41.08073100
49SRPK11.07802640
50BTK1.07579591
51DAPK21.06020358
52OXSR11.03117238
53CASK1.00748526
54EIF2AK21.00090947
55MAP4K20.98288538
56PDK20.98173748
57FES0.97816731
58ADRBK20.97168519
59CSNK1G10.97083917
60ERBB30.96720230
61BUB10.96440496
62TESK20.96379071
63BCKDK0.95726035
64BRAF0.95686068
65LYN0.95022917
66MAPK130.94895510
67TAOK30.93646158
68TESK10.93590694
69LCK0.91270336
70MAP2K60.89020215
71PIM10.88477232
72GRK10.87618587
73CSNK1G30.87422483
74ERN10.85115474
75BRSK20.84005382
76FLT30.83430385
77CCNB10.83220437
78YES10.82472001
79RIPK40.82404929
80MAP3K130.81639277
81CHUK0.80721980
82AKT30.79903402
83FGFR40.79092003
84TGFBR10.78366542
85JAK10.76466583
86CDC70.75263529
87CSNK1G20.74025853
88PASK0.72900110
89MKNK20.71454785
90PLK20.70582136
91TIE10.70460565
92LIMK10.70355283
93PRKCD0.69994199
94EPHA30.68273649
95TLK10.67259959
96PIK3CG0.66588730
97SGK20.66371875
98TNK20.65425017
99PRKCQ0.64748225
100MARK30.64529513
101PRKCE0.63644441
102CSK0.63452440
103BCR0.63404250
104FGFR30.62909814
105CSNK1A1L0.61283362
106MAP2K70.61221695
107MAP3K30.61187599
108NLK0.61036278
109ADRBK10.59177236
110RPS6KA40.58612273
111DAPK10.57759244
112FRK0.56822287
113PIK3CA0.56035238
114CAMKK20.55409408
115KIT0.54978763
116GRK60.54242871
117MKNK10.53333190
118PLK30.53154526
119MAPK120.52589246
120ZAK0.51734526
121MATK0.49670232
122CLK10.48185580
123CSF1R0.47763776
124RPS6KA50.46989481
125CSNK2A10.46208819
126STK40.46060463
127BLK0.45885614
128GRK50.45279522
129MAPK70.44192699
130OBSCN0.42989145
131MUSK0.42885445
132MAP3K110.42659931
133NME10.41818428
134DYRK20.41589536
135ARAF0.41538026
136DYRK30.40506759
137TNIK0.39618727
138FER0.39464034
139PTK2B0.39443820
140ERBB40.38716394
141BRSK10.38506596
142IGF1R0.38501533
143ATM0.36018457
144FGFR20.34992927
145IRAK10.34022864

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.44175929
2Proteasome_Homo sapiens_hsa030503.11903587
3Graft-versus-host disease_Homo sapiens_hsa053322.83318489
4Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.63448865
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.39008977
6Allograft rejection_Homo sapiens_hsa053302.38188228
7Homologous recombination_Homo sapiens_hsa034402.08563591
8Propanoate metabolism_Homo sapiens_hsa006402.07594935
9Maturity onset diabetes of the young_Homo sapiens_hsa049501.98117271
10Type I diabetes mellitus_Homo sapiens_hsa049401.97128900
11Pentose and glucuronate interconversions_Homo sapiens_hsa000401.89336867
12Primary bile acid biosynthesis_Homo sapiens_hsa001201.87771760
13Intestinal immune network for IgA production_Homo sapiens_hsa046721.83877932
14Phototransduction_Homo sapiens_hsa047441.82136530
15Oxidative phosphorylation_Homo sapiens_hsa001901.79406600
16RNA polymerase_Homo sapiens_hsa030201.77205537
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.72215573
18Legionellosis_Homo sapiens_hsa051341.59421028
19Peroxisome_Homo sapiens_hsa041461.54004928
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.53467367
21Drug metabolism - other enzymes_Homo sapiens_hsa009831.52047503
22Parkinsons disease_Homo sapiens_hsa050121.51940619
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.51886146
24Non-homologous end-joining_Homo sapiens_hsa034501.51096731
25Fanconi anemia pathway_Homo sapiens_hsa034601.49440418
26Pyrimidine metabolism_Homo sapiens_hsa002401.49245674
27Autoimmune thyroid disease_Homo sapiens_hsa053201.46768311
28Ribosome_Homo sapiens_hsa030101.46682545
29Primary immunodeficiency_Homo sapiens_hsa053401.45276463
30Staphylococcus aureus infection_Homo sapiens_hsa051501.37603660
31Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.37117306
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.35716939
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35708672
34One carbon pool by folate_Homo sapiens_hsa006701.34933687
35Selenocompound metabolism_Homo sapiens_hsa004501.33579517
36Tryptophan metabolism_Homo sapiens_hsa003801.32369667
37Sulfur metabolism_Homo sapiens_hsa009201.32144563
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.31992265
39Rheumatoid arthritis_Homo sapiens_hsa053231.31139670
40NF-kappa B signaling pathway_Homo sapiens_hsa040641.29151130
41Leishmaniasis_Homo sapiens_hsa051401.28829132
42Antigen processing and presentation_Homo sapiens_hsa046121.27148727
43Histidine metabolism_Homo sapiens_hsa003401.26447198
44Phenylalanine metabolism_Homo sapiens_hsa003601.24406008
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.22182713
46Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.20337646
47Base excision repair_Homo sapiens_hsa034101.19706991
48Tyrosine metabolism_Homo sapiens_hsa003501.17515119
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.13220017
50Butanoate metabolism_Homo sapiens_hsa006501.12402265
51Measles_Homo sapiens_hsa051621.10297377
52Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.10075234
53Folate biosynthesis_Homo sapiens_hsa007901.09361667
54DNA replication_Homo sapiens_hsa030301.09095000
55Fatty acid elongation_Homo sapiens_hsa000621.08297198
56Chemical carcinogenesis_Homo sapiens_hsa052041.06721464
57Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.06693668
58SNARE interactions in vesicular transport_Homo sapiens_hsa041301.06646095
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.06098370
60Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.05392838
61Complement and coagulation cascades_Homo sapiens_hsa046101.00553723
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.99778582
63Linoleic acid metabolism_Homo sapiens_hsa005910.97253001
64Mismatch repair_Homo sapiens_hsa034300.95669145
65Other glycan degradation_Homo sapiens_hsa005110.95410465
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94928043
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.94851719
68Arachidonic acid metabolism_Homo sapiens_hsa005900.93005694
69Phagosome_Homo sapiens_hsa041450.91857429
70Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91688861
71Ether lipid metabolism_Homo sapiens_hsa005650.91675621
72Asthma_Homo sapiens_hsa053100.91146166
73Basal transcription factors_Homo sapiens_hsa030220.91010097
74RNA transport_Homo sapiens_hsa030130.88507538
75RNA degradation_Homo sapiens_hsa030180.87302976
76Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86852972
77Alzheimers disease_Homo sapiens_hsa050100.83026296
78Huntingtons disease_Homo sapiens_hsa050160.82478221
79Toll-like receptor signaling pathway_Homo sapiens_hsa046200.82278020
80Pertussis_Homo sapiens_hsa051330.80751408
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80529889
82Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80472796
83Galactose metabolism_Homo sapiens_hsa000520.78496202
84Herpes simplex infection_Homo sapiens_hsa051680.78103878
85Hematopoietic cell lineage_Homo sapiens_hsa046400.78085365
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.77779177
87Steroid hormone biosynthesis_Homo sapiens_hsa001400.74952258
88* Purine metabolism_Homo sapiens_hsa002300.71764922
89Regulation of autophagy_Homo sapiens_hsa041400.71403135
90Retinol metabolism_Homo sapiens_hsa008300.71161881
91Glutathione metabolism_Homo sapiens_hsa004800.70161487
92Fatty acid degradation_Homo sapiens_hsa000710.70013673
93Arginine biosynthesis_Homo sapiens_hsa002200.69508749
94Nucleotide excision repair_Homo sapiens_hsa034200.69383086
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67106725
96Vitamin digestion and absorption_Homo sapiens_hsa049770.66083362
97Influenza A_Homo sapiens_hsa051640.64775431
98Olfactory transduction_Homo sapiens_hsa047400.64769779
99ABC transporters_Homo sapiens_hsa020100.64277885
100Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63250134
101Starch and sucrose metabolism_Homo sapiens_hsa005000.62604223
102African trypanosomiasis_Homo sapiens_hsa051430.61943290
103Pyruvate metabolism_Homo sapiens_hsa006200.61655462
104Collecting duct acid secretion_Homo sapiens_hsa049660.61111877
105Vibrio cholerae infection_Homo sapiens_hsa051100.59721359
106Malaria_Homo sapiens_hsa051440.59578846
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.59138494
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58900064
109Caffeine metabolism_Homo sapiens_hsa002320.58374758
110beta-Alanine metabolism_Homo sapiens_hsa004100.57426956
111Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57181773
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55292586
113Circadian rhythm_Homo sapiens_hsa047100.55006613
114Metabolic pathways_Homo sapiens_hsa011000.54907271
115Spliceosome_Homo sapiens_hsa030400.54076285
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.53438429
117Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52965154
118Cysteine and methionine metabolism_Homo sapiens_hsa002700.51652107
119Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.50669543
120Nitrogen metabolism_Homo sapiens_hsa009100.49462780
121Glycosaminoglycan degradation_Homo sapiens_hsa005310.48732501
122Lysosome_Homo sapiens_hsa041420.48687594
123Epstein-Barr virus infection_Homo sapiens_hsa051690.48502961
124Cardiac muscle contraction_Homo sapiens_hsa042600.48193215
125Cyanoamino acid metabolism_Homo sapiens_hsa004600.33524531
126N-Glycan biosynthesis_Homo sapiens_hsa005100.31972599
127Mineral absorption_Homo sapiens_hsa049780.29898633
128Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28787654
129Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.28174280
130Fatty acid metabolism_Homo sapiens_hsa012120.25648480

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