AEN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.69790922
2polyketide metabolic process (GO:0030638)5.08735307
3doxorubicin metabolic process (GO:0044598)5.08735307
4daunorubicin metabolic process (GO:0044597)5.08735307
5sphingosine metabolic process (GO:0006670)4.79287708
6DNA replication-dependent nucleosome organization (GO:0034723)4.67162769
7DNA replication-dependent nucleosome assembly (GO:0006335)4.67162769
8formation of translation preinitiation complex (GO:0001731)4.54156895
9regulation of nuclear cell cycle DNA replication (GO:0033262)4.53847399
10regulation of gene silencing by RNA (GO:0060966)4.52008890
11regulation of posttranscriptional gene silencing (GO:0060147)4.52008890
12regulation of gene silencing by miRNA (GO:0060964)4.52008890
13protein localization to chromosome, centromeric region (GO:0071459)4.49336688
14mitotic sister chromatid segregation (GO:0000070)4.46955071
15nuclear pore organization (GO:0006999)4.44142160
16nuclear pore complex assembly (GO:0051292)4.40178739
17heterochromatin organization (GO:0070828)4.30689581
18regulation of telomere maintenance via telomerase (GO:0032210)4.29067575
19ribosome biogenesis (GO:0042254)4.27082038
20DNA replication checkpoint (GO:0000076)4.20234748
21protein complex localization (GO:0031503)4.13056457
22DNA unwinding involved in DNA replication (GO:0006268)4.11746400
23regulation of mammary gland epithelial cell proliferation (GO:0033599)4.09902415
24folic acid-containing compound biosynthetic process (GO:0009396)4.09220374
25diol metabolic process (GO:0034311)4.04741332
26negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.98622488
27DNA replication initiation (GO:0006270)3.86914772
28rRNA modification (GO:0000154)3.85512410
29sister chromatid segregation (GO:0000819)3.85063067
30cellular protein complex localization (GO:0034629)3.82103894
31histone H4-K12 acetylation (GO:0043983)3.81716683
32regulation of translation in response to stress (GO:0043555)3.80861314
33rRNA transcription (GO:0009303)3.79582856
34negative regulation of epidermis development (GO:0045683)3.78325451
35mitotic nuclear envelope disassembly (GO:0007077)3.73699766
36negative regulation of telomerase activity (GO:0051974)3.71943406
37ribonucleoprotein complex biogenesis (GO:0022613)3.71764729
38regulation of translational termination (GO:0006449)3.67397796
39positive regulation of SMAD protein import into nucleus (GO:0060391)3.64527622
40negative regulation of cell cycle G2/M phase transition (GO:1902750)3.64260877
41histone H4-K8 acetylation (GO:0043982)3.63709579
42histone H4-K5 acetylation (GO:0043981)3.63709579
43notochord development (GO:0030903)3.61773744
44rRNA methylation (GO:0031167)3.60481990
45ribosomal small subunit biogenesis (GO:0042274)3.57396781
46negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.57065680
47telomere maintenance via semi-conservative replication (GO:0032201)3.57026067
48IMP biosynthetic process (GO:0006188)3.56761231
49L-serine metabolic process (GO:0006563)3.53815445
50sphingoid metabolic process (GO:0046519)3.50667876
51nodal signaling pathway (GO:0038092)3.49666916
52DNA duplex unwinding (GO:0032508)3.48786942
53chromatin assembly (GO:0031497)3.48671761
54pseudouridine synthesis (GO:0001522)3.47705033
55nuclear envelope disassembly (GO:0051081)3.47589062
56membrane disassembly (GO:0030397)3.47589062
57proline biosynthetic process (GO:0006561)3.47524363
58DNA geometric change (GO:0032392)3.45717837
59muscle organ morphogenesis (GO:0048644)3.43587438
60regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.37574112
61negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.34202695
62mitotic sister chromatid cohesion (GO:0007064)3.33747600
63pre-miRNA processing (GO:0031054)3.33201199
64mitotic metaphase plate congression (GO:0007080)3.32486407
65nucleobase biosynthetic process (GO:0046112)3.30905738
66pore complex assembly (GO:0046931)3.24702381
67cullin deneddylation (GO:0010388)3.22990637
68maturation of SSU-rRNA (GO:0030490)3.22806575
69regulation of response to osmotic stress (GO:0047484)3.20580337
70somite rostral/caudal axis specification (GO:0032525)3.19980115
71mitotic chromosome condensation (GO:0007076)3.18630468
72spliceosomal tri-snRNP complex assembly (GO:0000244)3.18051315
73aminoglycoside antibiotic metabolic process (GO:0030647)3.17914990
74IMP metabolic process (GO:0046040)3.15887207
75negative regulation of telomere maintenance (GO:0032205)3.15363743
76pteridine-containing compound biosynthetic process (GO:0042559)3.15036405
77histone arginine methylation (GO:0034969)3.12511013
78maintenance of protein location in nucleus (GO:0051457)3.10757233
79transcription from mitochondrial promoter (GO:0006390)3.09618522
80somatic hypermutation of immunoglobulin genes (GO:0016446)3.08356697
81somatic diversification of immune receptors via somatic mutation (GO:0002566)3.08356697
82establishment of integrated proviral latency (GO:0075713)3.07381452
83regulation of meiosis I (GO:0060631)3.07355722
84meiotic chromosome segregation (GO:0045132)3.07345704
85negative regulation of chromosome segregation (GO:0051985)3.07090015
86regulation of hippo signaling (GO:0035330)3.06464311
87DNA strand elongation involved in DNA replication (GO:0006271)3.02604920
88positive regulation of DNA-dependent DNA replication (GO:2000105)3.02080630
89positive regulation of chromosome segregation (GO:0051984)3.01431311
90mitochondrial RNA metabolic process (GO:0000959)3.00539995
91rRNA processing (GO:0006364)2.99618902
92embryonic process involved in female pregnancy (GO:0060136)2.99346474
93lipopolysaccharide biosynthetic process (GO:0009103)2.99297217
94regulation of sister chromatid cohesion (GO:0007063)2.98918544
95mitotic recombination (GO:0006312)2.98819059
96ribosome assembly (GO:0042255)2.98661551
97peptidyl-arginine omega-N-methylation (GO:0035247)2.97846308
98regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.97508453
99negative regulation of mRNA processing (GO:0050686)2.96191856
100telomere maintenance via recombination (GO:0000722)2.95116716
101purine nucleobase biosynthetic process (GO:0009113)2.93145147
102protein deneddylation (GO:0000338)2.89623370
103rRNA metabolic process (GO:0016072)2.88252052
104tetrahydrofolate metabolic process (GO:0046653)2.87690479
105regulation of apoptotic process involved in morphogenesis (GO:1902337)2.87629890
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.87425796
107negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.87425796
108negative regulation of mitotic sister chromatid segregation (GO:0033048)2.87425796
109negative regulation of mitotic sister chromatid separation (GO:2000816)2.87425796
110negative regulation of sister chromatid segregation (GO:0033046)2.87425796
111DNA strand elongation (GO:0022616)2.87270429
112regulation of double-strand break repair (GO:2000779)2.85341317
113negative regulation of gene silencing (GO:0060969)2.85137667
114regulation of chromosome segregation (GO:0051983)2.82566707
115mitotic G2/M transition checkpoint (GO:0044818)2.81308716
116serine family amino acid biosynthetic process (GO:0009070)2.80265593
117maternal placenta development (GO:0001893)2.79760927
118paraxial mesoderm development (GO:0048339)2.79525183
119mitochondrial DNA metabolic process (GO:0032042)2.78026176
120ribosomal large subunit biogenesis (GO:0042273)2.77497070
121RNA stabilization (GO:0043489)2.76478422
122mRNA stabilization (GO:0048255)2.76478422
123trophectodermal cell differentiation (GO:0001829)2.76061035
124regulation of mitotic metaphase/anaphase transition (GO:0030071)2.74732779
125regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.74732779
126negative regulation of epidermal cell differentiation (GO:0045605)2.74526452
127mitotic spindle checkpoint (GO:0071174)2.73538092
128negative regulation of mRNA metabolic process (GO:1903312)2.73528961
129regulation of gene silencing (GO:0060968)2.72196172
130DNA conformation change (GO:0071103)2.71427092
131chromosome condensation (GO:0030261)2.70885612
132DNA damage response, detection of DNA damage (GO:0042769)2.70884871
133spindle checkpoint (GO:0031577)2.70670128
134chromatin remodeling at centromere (GO:0031055)2.69604576
135cell fate commitment involved in formation of primary germ layer (GO:0060795)2.69023025
136chromatin assembly or disassembly (GO:0006333)2.68784982
137folic acid metabolic process (GO:0046655)2.68526977
138metaphase plate congression (GO:0051310)2.67711969
139mitotic spindle assembly checkpoint (GO:0007094)2.67532318
140spliceosomal snRNP assembly (GO:0000387)2.67282365
141DNA synthesis involved in DNA repair (GO:0000731)2.66974518
142protein localization to chromosome (GO:0034502)2.66638979
143regulation of spindle organization (GO:0090224)2.66572847
144regulation of centriole replication (GO:0046599)2.66555290
145primitive streak formation (GO:0090009)2.66037907
146spindle assembly (GO:0051225)2.65821614
147regulation of translational fidelity (GO:0006450)2.65419434
148attachment of spindle microtubules to kinetochore (GO:0008608)2.65248944
149CENP-A containing nucleosome assembly (GO:0034080)2.62534144

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.68225510
2MYC_18555785_ChIP-Seq_MESCs_Mouse3.88930012
3KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.52473026
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.52473026
5KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.52473026
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.37810270
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.17225233
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.04737332
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.04625840
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.91753114
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.61889216
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.58698394
13POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.49097213
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.45216106
15SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.27859735
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.27421782
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.14506987
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.09462747
19NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.04054350
20ETS1_20019798_ChIP-Seq_JURKAT_Human2.02611348
21TP63_19390658_ChIP-ChIP_HaCaT_Human2.01358616
22STAT3_1855785_ChIP-Seq_MESCs_Mouse2.01218529
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.99431591
24TCF3_18692474_ChIP-Seq_MEFs_Mouse1.95345588
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.95059908
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.93481572
27NANOG_18555785_ChIP-Seq_MESCs_Mouse1.92576871
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.91930318
29NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.90298956
30XRN2_22483619_ChIP-Seq_HELA_Human1.89629165
31NELFA_20434984_ChIP-Seq_ESCs_Mouse1.88482180
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82691074
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.80091029
34GABP_17652178_ChIP-ChIP_JURKAT_Human1.78909503
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.74860977
36SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.73292893
37E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72470510
38MYC_22102868_ChIP-Seq_BL_Human1.71508516
39BP1_19119308_ChIP-ChIP_Hs578T_Human1.69417080
40KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.67211758
41TCF3_18692474_ChIP-Seq_MESCs_Mouse1.66306951
42POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.65879806
43ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.65052083
44AR_21909140_ChIP-Seq_LNCAP_Human1.64343797
45HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.59059312
46TP63_17297297_ChIP-ChIP_HaCaT_Human1.57539254
47* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.55729650
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52635254
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.49452626
50TTF2_22483619_ChIP-Seq_HELA_Human1.46942729
51FOXP3_21729870_ChIP-Seq_TREG_Human1.46621658
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.46580478
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.45576884
54DCP1A_22483619_ChIP-Seq_HELA_Human1.44362938
55NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.42050927
56CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.41030547
57ZNF263_19887448_ChIP-Seq_K562_Human1.40515489
58VDR_23849224_ChIP-Seq_CD4+_Human1.39266946
59CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.39196346
60GABP_19822575_ChIP-Seq_HepG2_Human1.38989711
61HIF1A_21447827_ChIP-Seq_MCF-7_Human1.37374351
62NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.35498433
63ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35121212
64SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.35041055
65CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.34521564
66KLF4_18555785_ChIP-Seq_MESCs_Mouse1.30701222
67ELF1_17652178_ChIP-ChIP_JURKAT_Human1.30007571
68ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.29446546
69E2F1_21310950_ChIP-Seq_MCF-7_Human1.29172167
70THAP11_20581084_ChIP-Seq_MESCs_Mouse1.27651098
71OCT4_18692474_ChIP-Seq_MEFs_Mouse1.26736914
72* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25839054
73ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.25254307
74KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.23146593
75NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.20845189
76KDM5A_27292631_Chip-Seq_BREAST_Human1.20489662
77SOX2_18692474_ChIP-Seq_MEFs_Mouse1.19985916
78PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19375079
79ESR1_15608294_ChIP-ChIP_MCF-7_Human1.19023637
80HOXB4_20404135_ChIP-ChIP_EML_Mouse1.15685730
81DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14070190
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.13348612
83NANOG_18692474_ChIP-Seq_MEFs_Mouse1.13291876
84SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13135401
85POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.12352679
86POU5F1_16518401_ChIP-PET_MESCs_Mouse1.12042997
87CIITA_25753668_ChIP-Seq_RAJI_Human1.08907820
88* NOTCH1_21737748_ChIP-Seq_TLL_Human1.08345496
89PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.07731071
90PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05709852
91PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05575932
92NANOG_21062744_ChIP-ChIP_HESCs_Human1.05181435
93SOX2_18692474_ChIP-Seq_MESCs_Mouse1.04135693
94CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03351483
95DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03175271
96HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.02687750
97MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.02523385
98SOX17_20123909_ChIP-Seq_XEN_Mouse1.01393407
99TFEB_21752829_ChIP-Seq_HELA_Human1.00980963
100SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.00670922
101YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.00519071
102ELK1_19687146_ChIP-ChIP_HELA_Human1.00433748
103TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.99895612
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98857061
105NANOG_16153702_ChIP-ChIP_HESCs_Human0.98258209
106CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.95730354
107SOX2_16153702_ChIP-ChIP_HESCs_Human0.95426551
108NANOG_18692474_ChIP-Seq_MESCs_Mouse0.95300410
109* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.95298994
110SRF_21415370_ChIP-Seq_HL-1_Mouse0.94802043
111CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.93749733
112* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93116697
113TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92680282
114ELK1_22589737_ChIP-Seq_MCF10A_Human0.92205642
115CHD1_26751641_Chip-Seq_LNCaP_Human0.91561831
116SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.90567762
117TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.90001048
118ELK3_25401928_ChIP-Seq_HUVEC_Human0.88139854
119ZFP281_18757296_ChIP-ChIP_E14_Mouse0.87824487
120TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.87291439
121* ATF3_27146783_Chip-Seq_COLON_Human0.86811523
122* TP53_22127205_ChIP-Seq_IMR90_Human0.85640644

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004957_abnormal_blastocyst_morpholog3.80205240
2MP0003136_yellow_coat_color3.78701590
3MP0010352_gastrointestinal_tract_polyps3.13320672
4MP0008057_abnormal_DNA_replication3.10184237
5MP0003111_abnormal_nucleus_morphology3.03070622
6MP0005171_absent_coat_pigmentation2.95962602
7MP0003705_abnormal_hypodermis_morpholog2.94548794
8MP0003693_abnormal_embryo_hatching2.94346612
9MP0002837_dystrophic_cardiac_calcinosis2.81418416
10MP0003077_abnormal_cell_cycle2.76757061
11MP0003890_abnormal_embryonic-extraembry2.68109575
12MP0010030_abnormal_orbit_morphology2.66435115
13MP0006292_abnormal_olfactory_placode2.66312324
14MP0010094_abnormal_chromosome_stability2.56736039
15MP0004264_abnormal_extraembryonic_tissu2.46801980
16MP0003123_paternal_imprinting2.17436064
17MP0001672_abnormal_embryogenesis/_devel2.11803220
18MP0005380_embryogenesis_phenotype2.11803220
19MP0004233_abnormal_muscle_weight2.11716059
20MP0008932_abnormal_embryonic_tissue2.11437302
21MP0000350_abnormal_cell_proliferation2.10753383
22MP0008007_abnormal_cellular_replicative2.01431287
23MP0003011_delayed_dark_adaptation1.97675025
24MP0001730_embryonic_growth_arrest1.97101361
25MP0003984_embryonic_growth_retardation1.94171877
26MP0002254_reproductive_system_inflammat1.93768574
27MP0002088_abnormal_embryonic_growth/wei1.92619702
28MP0005257_abnormal_intraocular_pressure1.86863105
29MP0001293_anophthalmia1.83967349
30MP0000537_abnormal_urethra_morphology1.77152614
31MP0002085_abnormal_embryonic_tissue1.72721281
32MP0002084_abnormal_developmental_patter1.69944396
33MP0005394_taste/olfaction_phenotype1.64288605
34MP0005499_abnormal_olfactory_system1.64288605
35MP0002086_abnormal_extraembryonic_tissu1.59988642
36MP0001849_ear_inflammation1.59893328
37MP0004197_abnormal_fetal_growth/weight/1.59367857
38MP0001697_abnormal_embryo_size1.58431723
39MP0002653_abnormal_ependyma_morphology1.57742533
40MP0001348_abnormal_lacrimal_gland1.55584529
41MP0003646_muscle_fatigue1.54729285
42MP0003121_genomic_imprinting1.52706544
43MP0002396_abnormal_hematopoietic_system1.52505373
44MP0004133_heterotaxia1.50777015
45MP0008058_abnormal_DNA_repair1.49551208
46MP0000490_abnormal_crypts_of1.47604246
47MP0000750_abnormal_muscle_regeneration1.46986276
48MP0003119_abnormal_digestive_system1.46216204
49MP0002080_prenatal_lethality1.45606394
50MP0009672_abnormal_birth_weight1.45110946
51MP0002938_white_spotting1.43712067
52MP0005075_abnormal_melanosome_morpholog1.42562769
53MP0002332_abnormal_exercise_endurance1.41379899
54MP0002092_abnormal_eye_morphology1.40519379
55MP0000428_abnormal_craniofacial_morphol1.34499441
56MP0004858_abnormal_nervous_system1.34080805
57MP0005023_abnormal_wound_healing1.32756843
58MP0003806_abnormal_nucleotide_metabolis1.32316358
59MP0000049_abnormal_middle_ear1.30339948
60MP0001346_abnormal_lacrimal_gland1.27423414
61MP0003786_premature_aging1.25822661
62MP0006035_abnormal_mitochondrial_morpho1.25506922
63MP0001661_extended_life_span1.25117293
64MP0000678_abnormal_parathyroid_gland1.24894497
65MP0003566_abnormal_cell_adhesion1.23792233
66MP0000313_abnormal_cell_death1.23562063
67MP0002932_abnormal_joint_morphology1.16529283
68MP0003941_abnormal_skin_development1.16066311
69MP0002269_muscular_atrophy1.11579813
70MP0000762_abnormal_tongue_morphology1.10614061
71MP0003938_abnormal_ear_development1.08867524
72MP0000432_abnormal_head_morphology1.08348905
73MP0002111_abnormal_tail_morphology1.04143691
74MP0003755_abnormal_palate_morphology1.03655211
75MP0003385_abnormal_body_wall1.01848114
76MP0002160_abnormal_reproductive_system1.01133619
77MP0005623_abnormal_meninges_morphology1.00637474
78MP0005451_abnormal_body_composition0.98552072
79MP0003942_abnormal_urinary_system0.98061149
80MP0002127_abnormal_cardiovascular_syste0.97850017
81MP0005367_renal/urinary_system_phenotyp0.97429259
82MP0000516_abnormal_urinary_system0.97429259
83MP0010307_abnormal_tumor_latency0.97391426
84MP0000358_abnormal_cell_content/0.97136857
85MP0005266_abnormal_metabolism0.97053629
86MP0002019_abnormal_tumor_incidence0.95473295
87MP0002233_abnormal_nose_morphology0.94985345
88MP0002163_abnormal_gland_morphology0.94746687
89MP0002114_abnormal_axial_skeleton0.94551666
90MP0003315_abnormal_perineum_morphology0.93869213
91MP0003122_maternal_imprinting0.93255237
92MP0005076_abnormal_cell_differentiation0.92911005
93MP0002089_abnormal_postnatal_growth/wei0.92691043
94MP0000749_muscle_degeneration0.92046786
95MP0002249_abnormal_larynx_morphology0.91485547
96MP0008789_abnormal_olfactory_epithelium0.90867628
97MP0003937_abnormal_limbs/digits/tail_de0.90551315
98MP0003935_abnormal_craniofacial_develop0.90196936
99MP0009250_abnormal_appendicular_skeleto0.89917096
100MP0008770_decreased_survivor_rate0.85455445
101MP0003283_abnormal_digestive_organ0.85140158
102MP0000858_altered_metastatic_potential0.85099472
103MP0002075_abnormal_coat/hair_pigmentati0.84740006
104MP0002697_abnormal_eye_size0.84427507
105MP0001286_abnormal_eye_development0.83607978
106MP0005508_abnormal_skeleton_morphology0.82988817
107MP0001915_intracranial_hemorrhage0.81876650
108MP0008438_abnormal_cutaneous_collagen0.80486603
109MP0000733_abnormal_muscle_development0.80168939
110MP0002925_abnormal_cardiovascular_devel0.80088379
111MP0002751_abnormal_autonomic_nervous0.76925751
112MP0002210_abnormal_sex_determination0.76491606
113MP0002877_abnormal_melanocyte_morpholog0.76036915
114MP0005395_other_phenotype0.75854959
115MP0009053_abnormal_anal_canal0.75515893
116MP0005384_cellular_phenotype0.75354409
117MP0009703_decreased_birth_body0.72983263
118MP0005501_abnormal_skin_physiology0.72886503
119MP0004808_abnormal_hematopoietic_stem0.72818539
120MP0004381_abnormal_hair_follicle0.72771178
121MP0003861_abnormal_nervous_system0.72544186
122MP0001186_pigmentation_phenotype0.71289965
123MP0002116_abnormal_craniofacial_bone0.69145897
124MP0001243_abnormal_dermal_layer0.68933839
125MP0004272_abnormal_basement_membrane0.68459253
126MP0003718_maternal_effect0.66056572
127MP0005621_abnormal_cell_physiology0.65587262
128MP0003567_abnormal_fetal_cardiomyocyte0.65345181
129MP0001145_abnormal_male_reproductive0.64357703
130MP0003453_abnormal_keratinocyte_physiol0.63098737
131MP0000534_abnormal_ureter_morphology0.62584599
132MP0002138_abnormal_hepatobiliary_system0.59887188

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)4.69769896
2Multiple enchondromatosis (HP:0005701)4.51774161
3Ependymoma (HP:0002888)4.39630225
4Rib fusion (HP:0000902)3.82946558
5Trismus (HP:0000211)3.77164816
6Rhabdomyosarcoma (HP:0002859)3.52825694
7Colon cancer (HP:0003003)3.47823394
8Ulnar bowing (HP:0003031)3.25882633
9Neoplasm of striated muscle (HP:0009728)3.25209296
10Testicular atrophy (HP:0000029)3.23297812
11Hepatoblastoma (HP:0002884)3.22860114
12Chromosomal breakage induced by crosslinking agents (HP:0003221)3.19309272
13Progressive external ophthalmoplegia (HP:0000590)3.12814248
14Hypochromic microcytic anemia (HP:0004840)3.11980616
15Aplasia/hypoplasia of the humerus (HP:0006507)3.06626283
16Fused cervical vertebrae (HP:0002949)3.02372586
17Astrocytoma (HP:0009592)3.02108895
18Abnormality of the astrocytes (HP:0100707)3.02108895
19Squamous cell carcinoma (HP:0002860)3.00561873
20Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.98349826
21Abnormality of the lower motor neuron (HP:0002366)2.98283286
22Chromsome breakage (HP:0040012)2.97620276
23Selective tooth agenesis (HP:0001592)2.91680552
24Short humerus (HP:0005792)2.84573498
25Abnormality of the salivary glands (HP:0010286)2.78921179
26Progressive muscle weakness (HP:0003323)2.76546032
27Amelogenesis imperfecta (HP:0000705)2.75176614
28Increased connective tissue (HP:0009025)2.70547378
29Poikiloderma (HP:0001029)2.69210447
30Preauricular skin tag (HP:0000384)2.66104178
31Missing ribs (HP:0000921)2.61818445
32Entropion (HP:0000621)2.61778379
33Acanthocytosis (HP:0001927)2.61667407
34Protrusio acetabuli (HP:0003179)2.61584740
35Meckel diverticulum (HP:0002245)2.60961465
36Nephroblastoma (Wilms tumor) (HP:0002667)2.60875320
37Overlapping toe (HP:0001845)2.59017305
38Medulloblastoma (HP:0002885)2.56769678
39Partial duplication of thumb phalanx (HP:0009944)2.52861936
40Abnormality of the ileum (HP:0001549)2.45114249
41Embryonal renal neoplasm (HP:0011794)2.44119521
42Partial duplication of the phalanx of hand (HP:0009999)2.41277000
43Aplastic anemia (HP:0001915)2.39578027
44Aplasia/Hypoplasia of the uvula (HP:0010293)2.37765956
45Abnormal lung lobation (HP:0002101)2.36867855
46Skin tags (HP:0010609)2.36688549
47Glioma (HP:0009733)2.36580001
48Atresia of the external auditory canal (HP:0000413)2.35132240
49Premature ovarian failure (HP:0008209)2.34091304
50Vertebral arch anomaly (HP:0008438)2.33682938
51Ragged-red muscle fibers (HP:0003200)2.33470889
52Glossoptosis (HP:0000162)2.32638760
53Rectovaginal fistula (HP:0000143)2.32214500
54Rectal fistula (HP:0100590)2.32214500
55Rough bone trabeculation (HP:0100670)2.30547423
56Microretrognathia (HP:0000308)2.30097472
57Supernumerary spleens (HP:0009799)2.29339055
58Abnormal cartilage morphology (HP:0002763)2.29293136
59Neoplasm of the adrenal cortex (HP:0100641)2.29273467
60Rectal prolapse (HP:0002035)2.26638966
61IgA deficiency (HP:0002720)2.23716756
62Increased nuchal translucency (HP:0010880)2.23352977
63Impulsivity (HP:0100710)2.21604303
64Breast hypoplasia (HP:0003187)2.21580240
65Spastic diplegia (HP:0001264)2.19641509
66Septate vagina (HP:0001153)2.18694372
67Duplication of thumb phalanx (HP:0009942)2.17137809
68Muscle fibrillation (HP:0010546)2.15748898
69Ectopic kidney (HP:0000086)2.14947440
70Hand muscle atrophy (HP:0009130)2.14512103
71Abnormal umbilical cord blood vessels (HP:0011403)2.14138572
72Single umbilical artery (HP:0001195)2.14138572
73Abnormality of the fetal cardiovascular system (HP:0010948)2.14138572
74Cutaneous melanoma (HP:0012056)2.14005487
75Gastrointestinal carcinoma (HP:0002672)2.13948814
76Malignant gastrointestinal tract tumors (HP:0006749)2.13948814
77Upper limb muscle weakness (HP:0003484)2.11785709
78Premature rupture of membranes (HP:0001788)2.10900261
79Tongue fasciculations (HP:0001308)2.10464437
80Proximal placement of thumb (HP:0009623)2.10210631
81Abnormality of DNA repair (HP:0003254)2.08742506
82Abnormality of chromosome stability (HP:0003220)2.07538835
83Achilles tendon contracture (HP:0001771)2.06744006
84Angiofibromas (HP:0010615)2.05526469
85Adenoma sebaceum (HP:0009720)2.05526469
86Horseshoe kidney (HP:0000085)2.05323564
87Abnormality of the umbilical cord (HP:0010881)2.04850746
88Atrophy/Degeneration involving motor neurons (HP:0007373)2.04775045
89Deviation of the thumb (HP:0009603)2.04318887
90Abdominal situs inversus (HP:0003363)2.03937250
91Abnormality of abdominal situs (HP:0011620)2.03937250
92Intestinal fistula (HP:0100819)2.03288455
93Oral leukoplakia (HP:0002745)2.01691849
94Vertebral fusion (HP:0002948)2.01135105
95Aplasia/Hypoplasia of the sternum (HP:0006714)2.01079657
96Short thumb (HP:0009778)2.00650576
97Broad distal phalanx of finger (HP:0009836)2.00262908
98Type I transferrin isoform profile (HP:0003642)1.99800985
99Abnormality of the preputium (HP:0100587)1.98646400
100Absent radius (HP:0003974)1.98102042
101Duodenal stenosis (HP:0100867)1.97865655
102Small intestinal stenosis (HP:0012848)1.97865655
103Short 5th finger (HP:0009237)1.97714526
104Degeneration of anterior horn cells (HP:0002398)1.97490020
105Abnormality of the anterior horn cell (HP:0006802)1.97490020
106Birth length less than 3rd percentile (HP:0003561)1.96372786
107Vaginal fistula (HP:0004320)1.95912982
108Neoplasm of the colon (HP:0100273)1.94462233
109Aplasia/Hypoplasia of the sacrum (HP:0008517)1.92677709
110Neoplasm of the oral cavity (HP:0100649)1.91540442
111Small epiphyses (HP:0010585)1.91426377
112Shawl scrotum (HP:0000049)1.91396560
113Secondary amenorrhea (HP:0000869)1.90976838
114Renal duplication (HP:0000075)1.90880853
115Pendular nystagmus (HP:0012043)1.90838384
116Microvesicular hepatic steatosis (HP:0001414)1.89783329
117Nasolacrimal duct obstruction (HP:0000579)1.88693780
118Cortical dysplasia (HP:0002539)1.88235536
119Facial cleft (HP:0002006)1.87508943
120Distal upper limb amyotrophy (HP:0007149)1.87458369
121Upper limb amyotrophy (HP:0009129)1.87458369
122Abnormal number of incisors (HP:0011064)1.87034556
123Amyotrophic lateral sclerosis (HP:0007354)1.86979532
124Horizontal nystagmus (HP:0000666)1.86110918
125Reticulocytopenia (HP:0001896)1.85811657
126Absent forearm bone (HP:0003953)1.83369524
127Aplasia involving forearm bones (HP:0009822)1.83369524
128Hypoplasia of the pons (HP:0012110)1.82367123
129Tracheoesophageal fistula (HP:0002575)1.82290376
130Abnormality of cells of the erythroid lineage (HP:0012130)1.81312488
131Abnormality of the labia minora (HP:0012880)1.81073471
132Carpal bone hypoplasia (HP:0001498)1.80344958
133Large earlobe (HP:0009748)1.80328363
134Aplasia/Hypoplasia of the scapulae (HP:0006713)1.79881413
135Hypoplastic scapulae (HP:0000882)1.79881413
136Abnormality of the distal phalanges of the toes (HP:0010182)1.79874629
137Abnormality of the musculature of the hand (HP:0001421)1.79749142
138Patellar aplasia (HP:0006443)1.79449333
139Abnormality of the Achilles tendon (HP:0005109)1.78124770
140Embryonal neoplasm (HP:0002898)1.74143060
141Transposition of the great arteries (HP:0001669)1.72277202
142Abnormal connection of the cardiac segments (HP:0011545)1.72277202
143Abnormal ventriculo-arterial connection (HP:0011563)1.72277202
144Abnormality of the carotid arteries (HP:0005344)1.70369253
145Neoplasm of the pancreas (HP:0002894)1.70267762
146Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.68147077
147Abnormal glycosylation (HP:0012345)1.67776498
148Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67776498
149Abnormal protein N-linked glycosylation (HP:0012347)1.67776498
150Abnormal protein glycosylation (HP:0012346)1.67776498
151Parakeratosis (HP:0001036)1.67461619
152Congenital ichthyosiform erythroderma (HP:0007431)1.66968673
153Triphalangeal thumb (HP:0001199)1.66801434
154Absent thumb (HP:0009777)1.66360831
155Hypergonadotropic hypogonadism (HP:0000815)1.64544454
156Overriding aorta (HP:0002623)1.64469686
157Abnormal number of erythroid precursors (HP:0012131)1.61447602
158Abnormality of the duodenum (HP:0002246)1.60141211
159Sparse lateral eyebrow (HP:0005338)1.59118790
160Long palpebral fissure (HP:0000637)1.58914662

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK126.39820973
2BUB13.71599105
3EPHA23.13069141
4ERN13.03036386
5TTK2.99497477
6SMG12.87879519
7ZAK2.77206058
8CDC72.72225567
9GRK62.38052102
10WEE12.32028588
11GRK52.23272649
12PRKD32.11201442
13STK102.10155231
14CDK72.09209447
15IRAK31.98767174
16MAP3K101.84613509
17TAF11.82784858
18NEK21.82488523
19PAK41.80870324
20NEK11.80641311
21PLK11.75584011
22RPS6KB21.71246567
23MELK1.68358985
24EIF2AK11.60909324
25LATS21.58666832
26PBK1.58380583
27STK31.57313820
28TESK21.55611688
29NME21.55508956
30ERBB41.53100468
31CSF1R1.52523003
32CHEK21.48839939
33TYRO31.44956027
34VRK21.40536174
35MOS1.34661134
36SRPK11.32106405
37ADRBK21.28330029
38GRK11.24399730
39CHEK11.18362225
40AURKB1.17961636
41DYRK31.14701570
42MATK1.14606818
43AURKA1.11951652
44ALK1.10685284
45PIM21.09528227
46TGFBR21.09236772
47ICK1.09116708
48CDK41.08997384
49MAP3K81.08341671
50TLK11.05862109
51BRSK21.04835858
52TTN1.04044013
53EEF2K1.00966235
54MAPKAPK30.99691429
55MKNK20.98138203
56MAPK70.95561610
57ACVR1B0.92728960
58MTOR0.91007969
59ATR0.90414657
60AKT20.84680353
61MAP2K20.84089608
62PDK20.83857975
63PRKG20.83235094
64RPS6KA40.82652168
65SCYL20.79726150
66DAPK30.78375768
67CDK20.78088413
68CDK190.76923488
69BRAF0.75605212
70PAK20.74978714
71AKT30.74313879
72CSNK1A1L0.74052246
73TSSK60.73888166
74STK160.72909681
75CAMK1D0.71579858
76TRIM280.71155913
77PAK10.70487630
78STK380.69065416
79MKNK10.68317063
80PRKCI0.67701966
81NME10.66046741
82TESK10.65630157
83PRPF4B0.64982717
84ATM0.64880918
85TRIB30.64764224
86WNK10.64413213
87DDR20.64309759
88PTK20.63824269
89KSR20.60810401
90GRK70.60574981
91EIF2AK20.58352455
92PASK0.57880742
93FLT30.57582151
94PKN20.55932333
95BMPR1B0.55261782
96NLK0.55087536
97FGFR30.54996950
98PIM10.54608695
99CSNK1E0.52437332
100BCKDK0.52372911
101PLK30.52343858
102CAMK1G0.51970556
103STK38L0.51657665
104MAP3K30.51279318
105PDGFRA0.50927837
106BMX0.49945685
107MAP3K110.49728197
108MAP2K30.49598614
109LATS10.47678880
110LRRK20.47221640
111CAMK40.46086809
112ADRBK10.45986855
113VRK10.45957234
114CDK10.45866210
115FGFR40.45595050
116PLK40.44742847
117STK240.44592401
118CDK60.43626919
119EIF2AK30.43493330
120CDK90.42525657
121DYRK1B0.42014606
122MARK20.41347967
123BRSK10.40892873
124CDK80.40380667
125TAOK20.40204468
126STK40.39856087
127CSNK2A20.38919202
128TGFBR10.38663472
129BRD40.38207977
130FGFR10.37471625
131DYRK20.36713210
132MAP3K50.35698708
133PDK40.34236286
134PDK30.34236286
135MAP3K90.30205338
136MAPK110.28789068
137CSNK1G10.26508515
138CSNK1G30.25326775
139RPS6KA50.24151860

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.57974877
2DNA replication_Homo sapiens_hsa030303.73869915
3RNA transport_Homo sapiens_hsa030133.26539095
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.26282527
5Ribosome_Homo sapiens_hsa030103.16056830
6Mismatch repair_Homo sapiens_hsa034303.10728564
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.00210466
8One carbon pool by folate_Homo sapiens_hsa006702.99674065
9Spliceosome_Homo sapiens_hsa030402.77682710
10Vitamin B6 metabolism_Homo sapiens_hsa007502.62616324
11Cell cycle_Homo sapiens_hsa041102.38565077
12RNA polymerase_Homo sapiens_hsa030202.30685757
13Base excision repair_Homo sapiens_hsa034102.23597937
14p53 signaling pathway_Homo sapiens_hsa041152.15597941
15Homologous recombination_Homo sapiens_hsa034402.11544705
16Nucleotide excision repair_Homo sapiens_hsa034202.05519239
17Proteasome_Homo sapiens_hsa030502.03302929
18Fanconi anemia pathway_Homo sapiens_hsa034602.00405405
19Fructose and mannose metabolism_Homo sapiens_hsa000511.81041962
20mRNA surveillance pathway_Homo sapiens_hsa030151.76978064
21RNA degradation_Homo sapiens_hsa030181.76106079
22Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.73286089
23Pyrimidine metabolism_Homo sapiens_hsa002401.72942967
24N-Glycan biosynthesis_Homo sapiens_hsa005101.50436586
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.29999685
26Galactose metabolism_Homo sapiens_hsa000521.28342732
27Thyroid cancer_Homo sapiens_hsa052161.26868804
28Basal transcription factors_Homo sapiens_hsa030221.24308750
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.24170498
30Bladder cancer_Homo sapiens_hsa052191.23949897
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.21942526
32Sphingolipid metabolism_Homo sapiens_hsa006001.17537629
33Biosynthesis of amino acids_Homo sapiens_hsa012301.17529568
34MicroRNAs in cancer_Homo sapiens_hsa052061.17313825
35Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.14723943
36Basal cell carcinoma_Homo sapiens_hsa052171.13816868
37Non-homologous end-joining_Homo sapiens_hsa034501.08486809
38Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.03840556
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.00643964
40Hippo signaling pathway_Homo sapiens_hsa043901.00298505
41Pentose phosphate pathway_Homo sapiens_hsa000300.97491841
42Folate biosynthesis_Homo sapiens_hsa007900.96970095
43Viral carcinogenesis_Homo sapiens_hsa052030.96742671
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.94640235
45Selenocompound metabolism_Homo sapiens_hsa004500.91379592
46mTOR signaling pathway_Homo sapiens_hsa041500.87504193
47Arachidonic acid metabolism_Homo sapiens_hsa005900.86827569
48Pyruvate metabolism_Homo sapiens_hsa006200.86292321
49Sulfur relay system_Homo sapiens_hsa041220.86198172
50HTLV-I infection_Homo sapiens_hsa051660.84942914
51Small cell lung cancer_Homo sapiens_hsa052220.84904875
52Steroid biosynthesis_Homo sapiens_hsa001000.84587171
53Prostate cancer_Homo sapiens_hsa052150.83926101
54Central carbon metabolism in cancer_Homo sapiens_hsa052300.83459536
55Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82180624
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.81407092
57Carbon metabolism_Homo sapiens_hsa012000.78318008
58Hedgehog signaling pathway_Homo sapiens_hsa043400.77918604
592-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.76101414
60Epstein-Barr virus infection_Homo sapiens_hsa051690.74694353
61Cyanoamino acid metabolism_Homo sapiens_hsa004600.73536223
62Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71726730
63Purine metabolism_Homo sapiens_hsa002300.67543245
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67123105
65Proteoglycans in cancer_Homo sapiens_hsa052050.67069745
66Apoptosis_Homo sapiens_hsa042100.66883533
67Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.64600877
68Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64196598
69Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62964883
70Notch signaling pathway_Homo sapiens_hsa043300.62382044
71Herpes simplex infection_Homo sapiens_hsa051680.62252599
72Linoleic acid metabolism_Homo sapiens_hsa005910.62088647
73Pathways in cancer_Homo sapiens_hsa052000.60511036
74Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.59988100
75Systemic lupus erythematosus_Homo sapiens_hsa053220.58352980
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.57188312
77Adherens junction_Homo sapiens_hsa045200.55866274
78TGF-beta signaling pathway_Homo sapiens_hsa043500.55758628
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55520826
80Pancreatic cancer_Homo sapiens_hsa052120.54557376
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53171136
82Oocyte meiosis_Homo sapiens_hsa041140.52915989
83Tight junction_Homo sapiens_hsa045300.52717061
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49966836
85Acute myeloid leukemia_Homo sapiens_hsa052210.48863342
86Viral myocarditis_Homo sapiens_hsa054160.48519859
87Alcoholism_Homo sapiens_hsa050340.45450407
88Arginine and proline metabolism_Homo sapiens_hsa003300.43935616
89Hepatitis B_Homo sapiens_hsa051610.42636299
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42551869
91Antigen processing and presentation_Homo sapiens_hsa046120.42439139
92Colorectal cancer_Homo sapiens_hsa052100.41187929
93PI3K-Akt signaling pathway_Homo sapiens_hsa041510.39634428
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39448203
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.39306774
96Wnt signaling pathway_Homo sapiens_hsa043100.39253943
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38735690
98Endometrial cancer_Homo sapiens_hsa052130.38451205
99HIF-1 signaling pathway_Homo sapiens_hsa040660.38221696
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38186043
101Glutathione metabolism_Homo sapiens_hsa004800.36351590
102Chronic myeloid leukemia_Homo sapiens_hsa052200.34860731
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34642271
104Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33460302
105Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.33126614
106Glycosaminoglycan degradation_Homo sapiens_hsa005310.31953842
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31328530
108Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.30690518
109Legionellosis_Homo sapiens_hsa051340.30629391
110ECM-receptor interaction_Homo sapiens_hsa045120.30537550
111Other glycan degradation_Homo sapiens_hsa005110.29982122
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29957297
113Glioma_Homo sapiens_hsa052140.29956483
114Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.29934689
115Melanoma_Homo sapiens_hsa052180.29921387
116Metabolic pathways_Homo sapiens_hsa011000.29281945
117Focal adhesion_Homo sapiens_hsa045100.29001720
118Vitamin digestion and absorption_Homo sapiens_hsa049770.27713058
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.27209416
120FoxO signaling pathway_Homo sapiens_hsa040680.24230468
121AMPK signaling pathway_Homo sapiens_hsa041520.23939024
122Phenylalanine metabolism_Homo sapiens_hsa003600.23544184
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.23339579
124Leukocyte transendothelial migration_Homo sapiens_hsa046700.22985775
125Non-small cell lung cancer_Homo sapiens_hsa052230.21361419
126Lysine degradation_Homo sapiens_hsa003100.21114154
127Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.17257018

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