AFTPH

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.13210335
2T-helper 1 type immune response (GO:0042088)5.04275414
3mature B cell differentiation (GO:0002335)4.73687981
4mature B cell differentiation involved in immune response (GO:0002313)4.60201807
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.45964304
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.45964304
7antigen processing and presentation of endogenous antigen (GO:0019883)4.34718136
8positive regulation of gamma-delta T cell activation (GO:0046645)4.20984946
9B cell receptor signaling pathway (GO:0050853)4.10649690
10interferon-gamma secretion (GO:0072643)3.86492838
11defense response to protozoan (GO:0042832)3.81953342
12regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.67297622
13germinal center formation (GO:0002467)3.66872654
14T-helper cell differentiation (GO:0042093)3.66746739
15CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.66746739
16positive regulation of natural killer cell differentiation (GO:0032825)3.59479720
17regulation of interleukin-12 biosynthetic process (GO:0045075)3.54959172
18piRNA metabolic process (GO:0034587)3.54005924
19response to protozoan (GO:0001562)3.48461738
20immunoglobulin mediated immune response (GO:0016064)3.47863708
21detection of other organism (GO:0098543)3.46949693
22response to type I interferon (GO:0034340)3.46129397
23positive regulation of interferon-alpha production (GO:0032727)3.44446424
24cellular response to type I interferon (GO:0071357)3.40838102
25type I interferon signaling pathway (GO:0060337)3.40838102
26modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.37371460
27positive regulation by organism of defense response of other organism involved in symbiotic interact3.37371460
28modulation by symbiont of host immune response (GO:0052553)3.37371460
29positive regulation by symbiont of host defense response (GO:0052509)3.37371460
30modulation by symbiont of host defense response (GO:0052031)3.37371460
31modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.37371460
32phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.35558517
33regulation of B cell differentiation (GO:0045577)3.33416667
34regulation of interferon-alpha production (GO:0032647)3.32738539
35negative regulation of cell killing (GO:0031342)3.28318385
36negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.28318385
37regulation of interferon-beta biosynthetic process (GO:0045357)3.27573323
38negative regulation of interleukin-12 production (GO:0032695)3.25895376
39cellular extravasation (GO:0045123)3.21816844
40macrophage activation involved in immune response (GO:0002281)3.21696787
41detection of bacterium (GO:0016045)3.20700278
42leukotriene biosynthetic process (GO:0019370)3.20352108
43regulation of gamma-delta T cell differentiation (GO:0045586)3.20328403
44JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.16583906
45detection of molecule of bacterial origin (GO:0032490)3.13903794
46negative regulation of T cell mediated immunity (GO:0002710)3.12775982
47regulation of gamma-delta T cell activation (GO:0046643)3.12403688
48positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.08850830
49regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.06599691
50T cell differentiation involved in immune response (GO:0002292)3.06227606
51alpha-beta T cell differentiation involved in immune response (GO:0002293)3.06227606
52alpha-beta T cell activation involved in immune response (GO:0002287)3.06227606
53histone H3-K36 demethylation (GO:0070544)3.05392437
54regulation of mast cell degranulation (GO:0043304)3.05122526
55detection of external biotic stimulus (GO:0098581)2.99290713
56negative regulation of lymphocyte mediated immunity (GO:0002707)2.99272414
57positive regulation of mast cell activation (GO:0033005)2.98347412
58positive regulation of interleukin-10 production (GO:0032733)2.95935512
59macrophage activation (GO:0042116)2.94563837
60NIK/NF-kappaB signaling (GO:0038061)2.94197751
61growth hormone receptor signaling pathway (GO:0060396)2.93231873
62B cell mediated immunity (GO:0019724)2.92330142
63neutrophil activation involved in immune response (GO:0002283)2.91429391
64neutrophil activation (GO:0042119)2.91062617
65granulocyte activation (GO:0036230)2.90934075
66positive thymic T cell selection (GO:0045059)2.90656332
67microglial cell activation (GO:0001774)2.90588831
68myeloid dendritic cell differentiation (GO:0043011)2.90522451
69natural killer cell differentiation (GO:0001779)2.90437076
70interferon-gamma-mediated signaling pathway (GO:0060333)2.90359809
71negative regulation of erythrocyte differentiation (GO:0045647)2.89819117
72negative regulation of adaptive immune response (GO:0002820)2.89563446
73CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.89338640
74negative thymic T cell selection (GO:0045060)2.88274132
75response to muramyl dipeptide (GO:0032495)2.88122962
76positive regulation of interleukin-12 production (GO:0032735)2.87222061
77positive T cell selection (GO:0043368)2.85216703
78regulation of mast cell activation involved in immune response (GO:0033006)2.84150926
79positive regulation of granulocyte differentiation (GO:0030854)2.82228164
80response to interleukin-15 (GO:0070672)2.81886082
81positive regulation of B cell differentiation (GO:0045579)2.79707756
82production of molecular mediator involved in inflammatory response (GO:0002532)2.78450956
83B cell homeostasis (GO:0001782)2.78437454
84negative T cell selection (GO:0043383)2.77967753
85regulation of mast cell activation (GO:0033003)2.76059027
86regulation of alpha-beta T cell proliferation (GO:0046640)2.76006958
87dendritic cell differentiation (GO:0097028)2.75238290
88regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.74487133
89leukotriene metabolic process (GO:0006691)2.72947255
90negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.72476104
91negative regulation of T-helper cell differentiation (GO:0045623)2.72476104
92regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.72398407
93regulation of protein polyubiquitination (GO:1902914)2.72395021
94regulation of RIG-I signaling pathway (GO:0039535)2.69948445
95regulation of B cell receptor signaling pathway (GO:0050855)2.69153429
96negative regulation of leukocyte mediated immunity (GO:0002704)2.69130967
97megakaryocyte development (GO:0035855)2.68756484
98positive regulation of antigen processing and presentation (GO:0002579)2.67974902
99neutrophil mediated immunity (GO:0002446)2.67627645
100hepatocyte apoptotic process (GO:0097284)2.67043727
101Arp2/3 complex-mediated actin nucleation (GO:0034314)2.66735352
102regulation of leukocyte degranulation (GO:0043300)2.66360525
103DNA methylation involved in gamete generation (GO:0043046)2.65945653
104myeloid dendritic cell activation (GO:0001773)2.65882545
105T cell migration (GO:0072678)2.63899034
106positive regulation of cellular amide metabolic process (GO:0034250)2.63696148
107CD4-positive, alpha-beta T cell activation (GO:0035710)2.62624436
108detection of biotic stimulus (GO:0009595)2.62119679
109positive regulation of T cell cytokine production (GO:0002726)2.61909907
110positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.60876066
111antigen processing and presentation via MHC class Ib (GO:0002475)2.59813691
112synapsis (GO:0007129)2.58721549
113regulation of T-helper 1 cell differentiation (GO:0045625)2.58150446
114negative regulation of B cell proliferation (GO:0030889)2.56771089
115T cell selection (GO:0045058)2.56262042
116antigen receptor-mediated signaling pathway (GO:0050851)2.56100646
117regulation of myeloid leukocyte mediated immunity (GO:0002886)2.55949084
118regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.55733292
119histone demethylation (GO:0016577)2.54933364
120adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.54847446
121histone H3-K9 demethylation (GO:0033169)2.54479655
122regulation of interleukin-8 biosynthetic process (GO:0045414)2.53268550
123natural killer cell mediated immunity (GO:0002228)2.53226765
124natural killer cell mediated cytotoxicity (GO:0042267)2.53226765
125positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.52056596
126cellular response to growth hormone stimulus (GO:0071378)2.49640538
127response to host immune response (GO:0052572)2.48211586
128response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.48211586
129regulation of antigen processing and presentation (GO:0002577)2.47749547
130cytokine secretion (GO:0050663)2.47109599
131lymphocyte mediated immunity (GO:0002449)2.46759946
132regulation of hypersensitivity (GO:0002883)2.46554938
133regulation of chronic inflammatory response (GO:0002676)2.45231679
134positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.43386903
135myeloid cell activation involved in immune response (GO:0002275)2.43251582
136regulation of activation of Janus kinase activity (GO:0010533)2.42898291
137regulation of natural killer cell differentiation (GO:0032823)2.41973192
138negative regulation of interleukin-17 production (GO:0032700)2.40706543
139lipopolysaccharide-mediated signaling pathway (GO:0031663)2.39896599
140positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.38446698
141JAK-STAT cascade (GO:0007259)2.38311088
142regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.38304449
143response to host defenses (GO:0052200)2.37550417
144response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.37550417
145response to host (GO:0075136)2.37550417
146negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.37196258
147response to peptidoglycan (GO:0032494)2.36539694
148response to interferon-alpha (GO:0035455)2.36289998
149regulation of interleukin-12 production (GO:0032655)2.35662700
150alpha-beta T cell activation (GO:0046631)2.34821349
151positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.34403821

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.30152490
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.99154236
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.83698002
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.60108105
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.49203650
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.16853571
7* IRF8_27001747_Chip-Seq_BMDM_Mouse3.02686912
8STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.86744697
9STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.86722462
10* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.76628441
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.59162455
12* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.49191347
13Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.45019717
14GATA1_22025678_ChIP-Seq_K562_Human2.36243791
15* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.20883713
16RUNX_20019798_ChIP-Seq_JUKART_Human2.09023538
17* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.03705142
18SMAD_19615063_ChIP-ChIP_OVARY_Human2.00700814
19EGR1_19374776_ChIP-ChIP_THP-1_Human1.95288272
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.78074769
21RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.75956521
22MYB_21317192_ChIP-Seq_ERMYB_Mouse1.71776259
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60515287
24STAT4_19710469_ChIP-ChIP_TH1__Mouse1.55481824
25* MYB_26560356_Chip-Seq_TH2_Human1.53971201
26VDR_24787735_ChIP-Seq_THP-1_Human1.52946125
27SCL_19346495_ChIP-Seq_HPC-7_Human1.51245167
28ZNF217_24962896_ChIP-Seq_MCF-7_Human1.44898632
29* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.44373147
30SPI1_23127762_ChIP-Seq_K562_Human1.42323400
31VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.42000997
32TCF7_22412390_ChIP-Seq_EML_Mouse1.38379654
33GATA2_21666600_ChIP-Seq_HMVEC_Human1.33725173
34GATA3_27048872_Chip-Seq_THYMUS_Human1.33254637
35PU_27001747_Chip-Seq_BMDM_Mouse1.33207793
36MYB_26560356_Chip-Seq_TH1_Human1.30575493
37BP1_19119308_ChIP-ChIP_Hs578T_Human1.28289953
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.25312128
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.24725046
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21782022
41* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19768590
42MAF_26560356_Chip-Seq_TH1_Human1.19560003
43* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.17830279
44GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16876717
45MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.16030113
46ER_23166858_ChIP-Seq_MCF-7_Human1.14634395
47E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.14236587
48FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12376188
49SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12273366
50FOXO3_23340844_ChIP-Seq_DLD1_Human1.11212063
51PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10267864
52GATA3_26560356_Chip-Seq_TH2_Human1.09298824
53CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08623588
54LXR_22158963_ChIP-Seq_LIVER_Mouse1.08291269
55BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07806721
56VDR_24763502_ChIP-Seq_THP-1_Human1.07705003
57* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.05880041
58* RUNX1_22412390_ChIP-Seq_EML_Mouse1.05324060
59ESR1_20079471_ChIP-ChIP_T-47D_Human1.03983639
60IKZF1_21737484_ChIP-ChIP_HCT116_Human1.03344233
61GATA1_19941827_ChIP-Seq_MEL_Mouse1.01949596
62PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01382822
63EGR1_19032775_ChIP-ChIP_M12_Human1.01252230
64GATA1_19941826_ChIP-Seq_K562_Human1.00227667
65GATA2_19941826_ChIP-Seq_K562_Human0.99847796
66ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.99356823
67RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99034093
68NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.98324517
69EGR1_23403033_ChIP-Seq_LIVER_Mouse0.97411976
70SMRT_27268052_Chip-Seq_Bcells_Human0.97334062
71PRDM14_20953172_ChIP-Seq_ESCs_Human0.95293860
72TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94879404
73LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.94870750
74RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.94347279
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93019779
76ESR2_21235772_ChIP-Seq_MCF-7_Human0.92913794
77DROSHA_22980978_ChIP-Seq_HELA_Human0.92728048
78FLI1_27457419_Chip-Seq_LIVER_Mouse0.92368543
79NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92222760
80CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91518139
81KDM2B_26808549_Chip-Seq_DND41_Human0.91198444
82RXR_22108803_ChIP-Seq_LS180_Human0.90539029
83* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.90218776
84* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.90104504
85CDX2_19796622_ChIP-Seq_MESCs_Mouse0.90096705
86* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.89544241
87* SPI1_23547873_ChIP-Seq_NB4_Human0.89123012
88* TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.88761583
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.88603387
90LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.88054664
91FOXA2_19822575_ChIP-Seq_HepG2_Human0.88020667
92VDR_21846776_ChIP-Seq_THP-1_Human0.87938178
93KDM2B_26808549_Chip-Seq_SUP-B15_Human0.87079155
94* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86315290
95TFEB_21752829_ChIP-Seq_HELA_Human0.84936764
96NOTCH1_21737748_ChIP-Seq_TLL_Human0.84662856
97SMAD4_21799915_ChIP-Seq_A2780_Human0.84483304
98FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.84205795
99* TP63_23658742_ChIP-Seq_EP156T_Human0.83917785
100PKCTHETA_26484144_Chip-Seq_BREAST_Human0.83901788
101PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.83513876
102UTX_26944678_Chip-Seq_JUKART_Human0.82806367
103TP63_17297297_ChIP-ChIP_HaCaT_Human0.82469923
104KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.82406824
105TCF4_18268006_ChIP-ChIP_LS174T_Human0.81580326
106GATA3_26560356_Chip-Seq_TH1_Human0.81222570
107SOX2_20726797_ChIP-Seq_SW620_Human0.80482689
108RXR_22158963_ChIP-Seq_LIVER_Mouse0.78963174
109FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.78919878
110* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.78805802
111SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.78390998
112AHR_22903824_ChIP-Seq_MCF-7_Human0.78319078
113MAF_26560356_Chip-Seq_TH2_Human0.78198833
114THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.78122624
115TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77871100
116AR_25329375_ChIP-Seq_VCAP_Human0.77628261
117CMYC_18555785_Chip-Seq_ESCs_Mouse0.77466646
118ESR1_21235772_ChIP-Seq_MCF-7_Human0.76588222
119ARNT_22903824_ChIP-Seq_MCF-7_Human0.76036505
120VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.75386590
121MYC_22102868_ChIP-Seq_BL_Human0.74957268
122SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.74136522
123KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.74104154
124TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.73666365
125KDM2B_26808549_Chip-Seq_JURKAT_Human0.73577598
126CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.73347200
127PIAS1_25552417_ChIP-Seq_VCAP_Human0.73147441
128RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.72756243
129CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.72226603
130NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.72194069
131NRF2_20460467_ChIP-Seq_MEFs_Mouse0.72194069

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.10089996
2MP0005310_abnormal_salivary_gland2.92272981
3MP0002166_altered_tumor_susceptibility2.91057793
4MP0003303_peritoneal_inflammation2.88657324
5MP0003195_calcinosis2.85993167
6MP0003300_gastrointestinal_ulcer2.84244106
7MP0010234_abnormal_vibrissa_follicle2.69438323
8MP0005387_immune_system_phenotype2.69402836
9MP0001790_abnormal_immune_system2.69402836
10MP0004510_myositis2.68504993
11MP0000685_abnormal_immune_system2.68375431
12MP0006082_CNS_inflammation2.52604954
13MP0000569_abnormal_digit_pigmentation2.46975193
14MP0005671_abnormal_response_to2.44343424
15MP0009785_altered_susceptibility_to2.42896740
16MP0002006_tumorigenesis2.42653347
17MP0002138_abnormal_hepatobiliary_system2.31259117
18MP0005000_abnormal_immune_tolerance2.30618503
19MP0001800_abnormal_humoral_immune2.30224371
20MP0002148_abnormal_hypersensitivity_rea2.25790536
21MP0002254_reproductive_system_inflammat2.24073101
22MP0008877_abnormal_DNA_methylation2.19932108
23MP0003436_decreased_susceptibility_to2.18961731
24MP0005058_abnormal_lysosome_morphology2.12527143
25MP0002452_abnormal_antigen_presenting2.11423638
26MP0002419_abnormal_innate_immunity2.08157674
27MP0002723_abnormal_immune_serum2.08112227
28MP0005025_abnormal_response_to2.06137801
29MP0004947_skin_inflammation1.95387872
30MP0003656_abnormal_erythrocyte_physiolo1.88855271
31MP0001819_abnormal_immune_cell1.83392604
32MP0005464_abnormal_platelet_physiology1.80847107
33MP0002420_abnormal_adaptive_immunity1.80344945
34MP0003172_abnormal_lysosome_physiology1.79411293
35MP0002877_abnormal_melanocyte_morpholog1.73363272
36MP0003191_abnormal_cellular_cholesterol1.70110444
37MP0008004_abnormal_stomach_pH1.68193475
38MP0001348_abnormal_lacrimal_gland1.67920838
39MP0005451_abnormal_body_composition1.61665014
40MP0003075_altered_response_to1.61228750
41MP0010155_abnormal_intestine_physiology1.57921167
42MP0003045_fibrosis1.57032025
43MP0001873_stomach_inflammation1.51841137
44MP0008057_abnormal_DNA_replication1.49108047
45MP0003724_increased_susceptibility_to1.49047310
46MP0001853_heart_inflammation1.47555643
47MP0001845_abnormal_inflammatory_respons1.46587663
48MP0003763_abnormal_thymus_physiology1.44307814
49MP0002398_abnormal_bone_marrow1.43450931
50MP0005166_decreased_susceptibility_to1.42934864
51MP0000716_abnormal_immune_system1.40636109
52MP0005075_abnormal_melanosome_morpholog1.39944461
53MP0009764_decreased_sensitivity_to1.39322806
54MP0009333_abnormal_splenocyte_physiolog1.31776891
55MP0003787_abnormal_imprinting1.29788154
56MP0008469_abnormal_protein_level1.25322896
57MP0005076_abnormal_cell_differentiation1.23098750
58MP0002693_abnormal_pancreas_physiology1.21679996
59MP0003183_abnormal_peptide_metabolism1.21062411
60MP0000604_amyloidosis1.20350892
61MP0008260_abnormal_autophagy1.19693108
62MP0010307_abnormal_tumor_latency1.19301494
63MP0001501_abnormal_sleep_pattern1.19285947
64MP0002163_abnormal_gland_morphology1.18395742
65MP0004859_abnormal_synaptic_plasticity1.16775611
66MP0002928_abnormal_bile_duct1.15808576
67MP0002405_respiratory_system_inflammati1.15445054
68MP0004381_abnormal_hair_follicle1.14967691
69MP0003828_pulmonary_edema1.13759246
70MP0003866_abnormal_defecation1.12793921
71MP0002009_preneoplasia1.12458499
72MP0000689_abnormal_spleen_morphology1.09921152
73MP0005379_endocrine/exocrine_gland_phen1.09395136
74MP0003252_abnormal_bile_duct1.07486704
75MP0001533_abnormal_skeleton_physiology1.04490372
76MP0004808_abnormal_hematopoietic_stem1.04388418
77MP0002722_abnormal_immune_system1.04236904
78MP0002909_abnormal_adrenal_gland1.02437699
79MP0000015_abnormal_ear_pigmentation1.02260332
80MP0002396_abnormal_hematopoietic_system1.00457461
81MP0002998_abnormal_bone_remodeling1.00286866
82MP0002429_abnormal_blood_cell0.99546170
83MP0008961_abnormal_basal_metabolism0.98983332
84MP0005397_hematopoietic_system_phenotyp0.98117261
85MP0001545_abnormal_hematopoietic_system0.98117261
86MP0001765_abnormal_ion_homeostasis0.96955249
87MP0010678_abnormal_skin_adnexa0.95942080
88MP0003690_abnormal_glial_cell0.94417756
89MP0003448_altered_tumor_morphology0.94327285
90MP0002277_abnormal_respiratory_mucosa0.89287798
91MP0008995_early_reproductive_senescence0.89006507
92MP0005645_abnormal_hypothalamus_physiol0.88576913
93MP0005647_abnormal_sex_gland0.86696617
94MP0002136_abnormal_kidney_physiology0.86467250
95MP0009840_abnormal_foam_cell0.86344610
96MP0005167_abnormal_blood-brain_barrier0.85027783
97MP0002132_abnormal_respiratory_system0.84736448
98MP0000383_abnormal_hair_follicle0.82656907
99MP0004883_abnormal_blood_vessel0.82291028
100MP0000609_abnormal_liver_physiology0.82256079
101MP0005535_abnormal_body_temperature0.81769202
102MP0001851_eye_inflammation0.79620109
103MP0002139_abnormal_hepatobiliary_system0.78896937
104MP0005174_abnormal_tail_pigmentation0.77623591
105MP0000427_abnormal_hair_cycle0.76962739
106MP0004484_altered_response_of0.76565701
107MP0003091_abnormal_cell_migration0.76358517
108MP0009763_increased_sensitivity_to0.75920810
109MP0002168_other_aberrant_phenotype0.75538717
110MP0003453_abnormal_keratinocyte_physiol0.75346534
111MP0000703_abnormal_thymus_morphology0.75113553
112MP0002332_abnormal_exercise_endurance0.72643538
113MP0003943_abnormal_hepatobiliary_system0.70887981
114MP0001881_abnormal_mammary_gland0.69895168
115MP0009278_abnormal_bone_marrow0.69036162
116MP0003566_abnormal_cell_adhesion0.68569406
117MP0005164_abnormal_response_to0.67532072
118MP0000858_altered_metastatic_potential0.66791504
119MP0010329_abnormal_lipoprotein_level0.66416693
120MP0000371_diluted_coat_color0.65478363
121MP0009765_abnormal_xenobiotic_induced0.64310504
122MP0010352_gastrointestinal_tract_polyps0.64268196
123MP0000465_gastrointestinal_hemorrhage0.64069013
124MP0000249_abnormal_blood_vessel0.61380238
125MP0009643_abnormal_urine_homeostasis0.61176060
126MP0003879_abnormal_hair_cell0.60006583
127MP0004264_abnormal_extraembryonic_tissu0.59488054

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)4.08242532
2Autoimmune thrombocytopenia (HP:0001973)4.03358830
3Recurrent bacterial skin infections (HP:0005406)3.75979998
4Nasal polyposis (HP:0100582)3.62887541
5Increased IgE level (HP:0003212)3.51653213
6Recurrent abscess formation (HP:0002722)3.33319419
7Recurrent fungal infections (HP:0002841)3.24714802
8Recurrent viral infections (HP:0004429)3.16218498
9Autoimmune hemolytic anemia (HP:0001890)3.15556099
10Recurrent gram-negative bacterial infections (HP:0005420)3.11137346
11Abnormality of the nasal mucosa (HP:0000433)3.07830941
12Abnormal delayed hypersensitivity skin test (HP:0002963)3.06662267
13Chronic otitis media (HP:0000389)2.98467277
14Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.97381431
15Keratoconjunctivitis (HP:0001096)2.96355680
16Optic neuritis (HP:0100653)2.90380918
17Retrobulbar optic neuritis (HP:0100654)2.90380918
18Asymmetry of the thorax (HP:0001555)2.79456103
19Vasculitis (HP:0002633)2.78973538
20Encephalitis (HP:0002383)2.78700912
21Systemic lupus erythematosus (HP:0002725)2.78351159
22Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.77036031
23Thoracic kyphosis (HP:0002942)2.76325846
24Orchitis (HP:0100796)2.74059508
25Amyotrophic lateral sclerosis (HP:0007354)2.69245035
26Myositis (HP:0100614)2.68476998
27Obstructive lung disease (HP:0006536)2.64714692
28Chronic obstructive pulmonary disease (HP:0006510)2.64714692
29Abnormality of the fingertips (HP:0001211)2.62391584
30Interstitial pulmonary disease (HP:0006530)2.59414818
31Abnormality of the lumbar spine (HP:0100712)2.56543881
32Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.55130464
33Mediastinal lymphadenopathy (HP:0100721)2.54958215
34Recurrent sinusitis (HP:0011108)2.54815343
35Stomatitis (HP:0010280)2.53669180
36Increased cerebral lipofuscin (HP:0011813)2.47623047
37Abnormality of macrophages (HP:0004311)2.47281663
38Recurrent bronchitis (HP:0002837)2.46807634
39Periodontitis (HP:0000704)2.46300907
40Gastrointestinal stroma tumor (HP:0100723)2.45918088
41Myocardial infarction (HP:0001658)2.45686154
42Hemoptysis (HP:0002105)2.44035700
43Colitis (HP:0002583)2.43370267
44Neoplasm of the tracheobronchial system (HP:0100552)2.42268647
45Inflammation of the large intestine (HP:0002037)2.42194533
46Arterial thrombosis (HP:0004420)2.40976488
47Prostate neoplasm (HP:0100787)2.40426848
48Gangrene (HP:0100758)2.39088276
49Absent frontal sinuses (HP:0002688)2.38233121
50Hematochezia (HP:0002573)2.36611478
51Disinhibition (HP:0000734)2.35420778
52Panhypogammaglobulinemia (HP:0003139)2.34842056
53Recurrent skin infections (HP:0001581)2.34445204
54Chronic diarrhea (HP:0002028)2.31762472
55Epistaxis (HP:0000421)2.31249342
56Papillary thyroid carcinoma (HP:0002895)2.31248068
57Abnormality of the thoracic spine (HP:0100711)2.29669153
58Alveolar cell carcinoma (HP:0006519)2.27152223
59Abnormality of T cells (HP:0002843)2.26908235
60Thyroiditis (HP:0100646)2.26647935
61Inappropriate behavior (HP:0000719)2.26319838
62Cellulitis (HP:0100658)2.25575004
63Gastrointestinal inflammation (HP:0004386)2.24955131
64Pulmonary embolism (HP:0002204)2.23747376
65Gingivitis (HP:0000230)2.23718084
66Urticaria (HP:0001025)2.18412465
67Leukocytosis (HP:0001974)2.17978734
68Papilledema (HP:0001085)2.16477602
69Increased neuronal autofluorescent lipopigment (HP:0002074)2.15062259
70Elevated erythrocyte sedimentation rate (HP:0003565)2.14284758
71Chronic mucocutaneous candidiasis (HP:0002728)2.14099710
72Recurrent cutaneous fungal infections (HP:0011370)2.14099710
73Abnormality of T cell physiology (HP:0011840)2.13172284
74Agammaglobulinemia (HP:0004432)2.12908435
75Hypergammaglobulinemia (HP:0010702)2.12632925
76Chest pain (HP:0100749)2.12341106
77Abnormality of T cell number (HP:0011839)2.11553224
78Gingival bleeding (HP:0000225)2.11466674
79Pustule (HP:0200039)2.11128634
80Visual hallucinations (HP:0002367)2.08712563
81Gastrointestinal infarctions (HP:0005244)2.06395540
82Pulmonary infiltrates (HP:0002113)2.06079046
83Viral hepatitis (HP:0006562)2.05034181
84Abnormality of the prostate (HP:0008775)2.04258310
85Abnormal platelet function (HP:0011869)2.03147614
86Impaired platelet aggregation (HP:0003540)2.03147614
87Vacuolated lymphocytes (HP:0001922)2.02552463
88Episodic fever (HP:0001954)2.01405758
89Acute myeloid leukemia (HP:0004808)2.00941274
90Degeneration of the lateral corticospinal tracts (HP:0002314)1.99969095
91Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.99969095
92Acne (HP:0001061)1.99678290
93Volvulus (HP:0002580)1.98916101
94Meningitis (HP:0001287)1.98692344
95Dysostosis multiplex (HP:0000943)1.98216974
96Abnormality of the pleura (HP:0002103)1.97248827
97Fatigue (HP:0012378)1.97197377
98Slow saccadic eye movements (HP:0000514)1.96511751
99Decreased circulating renin level (HP:0003351)1.94634767
100Eosinophilia (HP:0001880)1.92053391
101Hypochromic anemia (HP:0001931)1.91233830
102Mucopolysacchariduria (HP:0008155)1.90802772
103Urinary glycosaminoglycan excretion (HP:0003541)1.90802772
104Abnormality of glycolipid metabolism (HP:0010969)1.90782205
105Abnormality of liposaccharide metabolism (HP:0010968)1.90782205
106Abnormality of glycosphingolipid metabolism (HP:0004343)1.90782205
107Glomerulopathy (HP:0100820)1.89734449
108Spontaneous hematomas (HP:0007420)1.88982504
109Keratoconjunctivitis sicca (HP:0001097)1.88887918
110Joint hemorrhage (HP:0005261)1.87929672
111Anorexia (HP:0002039)1.87637205
112Bronchitis (HP:0012387)1.87468112
113Menstrual irregularities (HP:0000858)1.87200232
114Skin rash (HP:0000988)1.86699682
115Recurrent pneumonia (HP:0006532)1.86696308
116Chronic sinusitis (HP:0011109)1.86184420
117Abnormality of chloride homeostasis (HP:0011422)1.85429050
118Prolonged bleeding time (HP:0003010)1.84987140
119Polyneuropathy (HP:0001271)1.84958549
120IgA deficiency (HP:0002720)1.84744917
121Increased IgM level (HP:0003496)1.84188664
122Abnormality of polysaccharide metabolism (HP:0011012)1.83719360
123Abnormality of glycosaminoglycan metabolism (HP:0004371)1.83719360
124Abnormality of mucopolysaccharide metabolism (HP:0011020)1.83719360
125Acute hepatic failure (HP:0006554)1.82767864
126Macroorchidism (HP:0000053)1.82183528
127Dynein arm defect of respiratory motile cilia (HP:0012255)1.81211278
128Absent/shortened dynein arms (HP:0200106)1.81211278
129Osteomyelitis (HP:0002754)1.80599215
130Gonadotropin excess (HP:0000837)1.79473189
131Hypoplasia of the thymus (HP:0000778)1.78813744
132IgM deficiency (HP:0002850)1.78382072
133Glomerulonephritis (HP:0000099)1.77611306
134Metabolic alkalosis (HP:0200114)1.76990471
135Thick nail (HP:0001805)1.76375513
136Abnormality of B cell number (HP:0010975)1.76195352
137B lymphocytopenia (HP:0010976)1.76195352
138Frequent falls (HP:0002359)1.76150623
139Abnormality of cells of the lymphoid lineage (HP:0012140)1.75954649
140T lymphocytopenia (HP:0005403)1.75880832
141Lymphopenia (HP:0001888)1.74996464
142Progressive visual loss (HP:0000529)1.74810636
143Keratitis (HP:0000491)1.74009045
144Erythema (HP:0010783)1.69961314
145Vertigo (HP:0002321)1.69196344
146Granulocytopenia (HP:0001913)1.68912530
147Papilloma (HP:0012740)1.68586391
148Verrucae (HP:0200043)1.68586391
149Arthralgia (HP:0002829)1.67923189
150Microcytic anemia (HP:0001935)1.67729348
151Curly hair (HP:0002212)1.66629289

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K143.44266141
2RIPK43.10526509
3TYK22.98798428
4MAP3K132.71089958
5JAK12.62453484
6FGFR32.35075859
7TAOK32.34793943
8JAK32.32614938
9PRPF4B2.32070953
10FGFR42.24014676
11TBK12.14930113
12MAP4K12.13940456
13CAMKK12.04188602
14IKBKE2.02811594
15CHUK1.76475406
16TXK1.75033342
17SIK21.69776082
18MAP2K31.68080515
19MAP3K21.67552566
20MAP3K91.67143478
21FRK1.64227110
22FGR1.57238712
23TGFBR21.57089300
24IKBKB1.53863779
25IRAK31.49656971
26IRAK41.48009703
27HCK1.46512080
28MAP3K61.44941132
29JAK21.44750955
30HIPK21.41567172
31STK241.41398435
32SYK1.39910803
33PASK1.39028516
34SGK31.34079828
35EPHA31.26542447
36EPHB11.25978370
37CAMK1D1.25938473
38ACVR1B1.25125965
39CAMK1G1.24081079
40PTK61.22167569
41CDK91.18998690
42TAOK11.18259253
43DAPK21.17310769
44ERN11.17108193
45MAP3K51.12254841
46SIK31.11654075
47CAMKK21.08359368
48NTRK31.07159665
49IRAK21.06828086
50BTK1.05261556
51KIT1.04668840
52ZAP701.03737389
53TNK21.02680126
54CDK61.02453938
55MAP3K101.02197631
56SGK20.99408838
57PINK10.97609827
58SCYL20.95737961
59RET0.95206063
60FES0.91941619
61PKN20.91090541
62CSF1R0.90301621
63LCK0.88580457
64IRAK10.85937909
65PIK3CG0.85825078
66PDK10.84673351
67BRD40.84591389
68CDK190.84409526
69NEK90.83726193
70RIPK10.83052297
71BMPR20.81871778
72CSK0.81732607
73STK100.79417270
74YES10.79124152
75ITK0.78960239
76MATK0.76590383
77OXSR10.74759890
78EIF2AK30.74162317
79KSR20.73362342
80TRPM70.69429342
81MAP2K60.69193697
82MARK30.67729978
83LYN0.66567222
84MAP3K40.66375475
85STK110.63547957
86PTK2B0.63508921
87WNK10.63203877
88PRKAA20.62403653
89GRK60.62030762
90EEF2K0.61796392
91PNCK0.61549567
92PRKCH0.60770451
93SGK10.60592171
94TEC0.60281324
95PIM10.60155552
96MAP3K70.59704571
97STK38L0.57376087
98RPS6KB10.56766665
99MARK20.55949792
100MAP3K10.55328828
101MAPK120.54513284
102TRIB30.54439317
103INSRR0.54328705
104BLK0.53820254
105ABL10.53515962
106ALK0.53511698
107NLK0.51623276
108EGFR0.51513670
109PRKCQ0.51440279
110STK380.50418196
111MST40.49627806
112MAP2K40.48576126
113NUAK10.48559041
114GSK3A0.47260862
115DYRK30.46436038
116MAP3K30.46330233
117FYN0.45615350
118TLK10.42335313
119PRKD30.41749339
120PDGFRB0.41598121
121PDPK10.40903868
122NEK60.40401264
123AKT30.40171384
124FGFR20.39636794
125MAPK110.39445064
126CDK120.39323620
127LMTK20.38806737
128FER0.38728236
129MAPK150.38210299
130GRK70.38025871
131CAMK40.37288728
132SGK4940.36490694
133SGK2230.36490694
134RPS6KA40.35737803

Predicted pathways (KEGG)

RankGene SetZ-score
1Allograft rejection_Homo sapiens_hsa053302.34590102
2Leishmaniasis_Homo sapiens_hsa051402.19513021
3Toll-like receptor signaling pathway_Homo sapiens_hsa046202.00836387
4Intestinal immune network for IgA production_Homo sapiens_hsa046721.94757757
5Osteoclast differentiation_Homo sapiens_hsa043801.91762390
6NF-kappa B signaling pathway_Homo sapiens_hsa040641.80822649
7Measles_Homo sapiens_hsa051621.67724403
8Type I diabetes mellitus_Homo sapiens_hsa049401.66091451
9B cell receptor signaling pathway_Homo sapiens_hsa046621.62951663
10Staphylococcus aureus infection_Homo sapiens_hsa051501.62687124
11NOD-like receptor signaling pathway_Homo sapiens_hsa046211.62143849
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.58017096
13TNF signaling pathway_Homo sapiens_hsa046681.50526256
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.48576960
15Graft-versus-host disease_Homo sapiens_hsa053321.45969756
16Autoimmune thyroid disease_Homo sapiens_hsa053201.39434736
17Influenza A_Homo sapiens_hsa051641.39050750
18Tuberculosis_Homo sapiens_hsa051521.38615520
19Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.37527453
20Toxoplasmosis_Homo sapiens_hsa051451.36819727
21Primary immunodeficiency_Homo sapiens_hsa053401.35936059
22Chemokine signaling pathway_Homo sapiens_hsa040621.34162003
23Pertussis_Homo sapiens_hsa051331.33023399
24Type II diabetes mellitus_Homo sapiens_hsa049301.28739571
25Asthma_Homo sapiens_hsa053101.24923721
26Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.23093386
27T cell receptor signaling pathway_Homo sapiens_hsa046601.22555308
28Viral myocarditis_Homo sapiens_hsa054161.19864093
29Jak-STAT signaling pathway_Homo sapiens_hsa046301.15548176
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.11070910
31Prolactin signaling pathway_Homo sapiens_hsa049171.10435105
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05960127
33African trypanosomiasis_Homo sapiens_hsa051431.05444657
34Antigen processing and presentation_Homo sapiens_hsa046121.04439704
35Olfactory transduction_Homo sapiens_hsa047401.02923333
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.02883053
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.02198044
38Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02115661
39Dorso-ventral axis formation_Homo sapiens_hsa043201.00045517
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99187180
41Caffeine metabolism_Homo sapiens_hsa002320.97654963
42Long-term potentiation_Homo sapiens_hsa047200.97008475
43Phagosome_Homo sapiens_hsa041450.95313576
44Hepatitis C_Homo sapiens_hsa051600.92008688
45Lysosome_Homo sapiens_hsa041420.90985112
46Rheumatoid arthritis_Homo sapiens_hsa053230.89260874
47ABC transporters_Homo sapiens_hsa020100.88533621
48Herpes simplex infection_Homo sapiens_hsa051680.87098400
49Legionellosis_Homo sapiens_hsa051340.86858818
50Hepatitis B_Homo sapiens_hsa051610.86390109
51Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86334821
52Chronic myeloid leukemia_Homo sapiens_hsa052200.86066032
53Salivary secretion_Homo sapiens_hsa049700.86060705
54Platelet activation_Homo sapiens_hsa046110.85645792
55Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82560663
56Hematopoietic cell lineage_Homo sapiens_hsa046400.81658948
57Salmonella infection_Homo sapiens_hsa051320.80976454
58Renin secretion_Homo sapiens_hsa049240.80797704
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80571056
60Adipocytokine signaling pathway_Homo sapiens_hsa049200.79410562
61Sphingolipid signaling pathway_Homo sapiens_hsa040710.79211059
62Gastric acid secretion_Homo sapiens_hsa049710.77557838
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.76958828
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76209815
65Apoptosis_Homo sapiens_hsa042100.76126570
66Pancreatic cancer_Homo sapiens_hsa052120.75518348
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.75401635
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75183822
69Insulin resistance_Homo sapiens_hsa049310.74996169
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74943714
71Renal cell carcinoma_Homo sapiens_hsa052110.73504145
72Acute myeloid leukemia_Homo sapiens_hsa052210.73475609
73Malaria_Homo sapiens_hsa051440.72370234
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.72289182
75Non-small cell lung cancer_Homo sapiens_hsa052230.71599630
76Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.71063392
77Inositol phosphate metabolism_Homo sapiens_hsa005620.69359488
78Selenocompound metabolism_Homo sapiens_hsa004500.69193342
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.67193487
80Estrogen signaling pathway_Homo sapiens_hsa049150.66276964
81AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66131650
82Regulation of autophagy_Homo sapiens_hsa041400.65190607
83Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64580300
84Choline metabolism in cancer_Homo sapiens_hsa052310.63323620
85Nitrogen metabolism_Homo sapiens_hsa009100.63292538
86Endometrial cancer_Homo sapiens_hsa052130.63211707
87Aldosterone synthesis and secretion_Homo sapiens_hsa049250.62701899
88GnRH signaling pathway_Homo sapiens_hsa049120.62320367
89Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61598935
90Prostate cancer_Homo sapiens_hsa052150.61503903
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59702591
92Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58890371
93Glioma_Homo sapiens_hsa052140.58792966
94Other glycan degradation_Homo sapiens_hsa005110.58609990
95FoxO signaling pathway_Homo sapiens_hsa040680.58223395
96Oxytocin signaling pathway_Homo sapiens_hsa049210.57600542
97Prion diseases_Homo sapiens_hsa050200.57477331
98Insulin secretion_Homo sapiens_hsa049110.56754714
99Circadian entrainment_Homo sapiens_hsa047130.56418422
100Pancreatic secretion_Homo sapiens_hsa049720.55874954
101Synaptic vesicle cycle_Homo sapiens_hsa047210.55824688
102Circadian rhythm_Homo sapiens_hsa047100.55480439
103cAMP signaling pathway_Homo sapiens_hsa040240.55265264
104Viral carcinogenesis_Homo sapiens_hsa052030.55050913
105Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54665439
106Epstein-Barr virus infection_Homo sapiens_hsa051690.54386384
107mTOR signaling pathway_Homo sapiens_hsa041500.54316800
108ErbB signaling pathway_Homo sapiens_hsa040120.53454092
109Endocytosis_Homo sapiens_hsa041440.53148517
110Maturity onset diabetes of the young_Homo sapiens_hsa049500.52845167
111Amphetamine addiction_Homo sapiens_hsa050310.52596032
112Morphine addiction_Homo sapiens_hsa050320.52326831
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.51131217
114Shigellosis_Homo sapiens_hsa051310.51048031
115Leukocyte transendothelial migration_Homo sapiens_hsa046700.50748062
116MAPK signaling pathway_Homo sapiens_hsa040100.50337671
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49355713
118VEGF signaling pathway_Homo sapiens_hsa043700.49294581
119Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47597664
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47467961
121Glutamatergic synapse_Homo sapiens_hsa047240.46991582
122Long-term depression_Homo sapiens_hsa047300.46375409
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.46232138
124Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44901064
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38895273
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35749121
127HIF-1 signaling pathway_Homo sapiens_hsa040660.33741094

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