

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.67449172 |
| 2 | cellular extravasation (GO:0045123) | 5.63575366 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.32674284 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.24031349 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.24031349 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 5.24031349 |
| 7 | positive regulation by symbiont of host defense response (GO:0052509) | 5.24031349 |
| 8 | modulation by symbiont of host defense response (GO:0052031) | 5.24031349 |
| 9 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.24031349 |
| 10 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.07822856 |
| 11 | negative regulation of cell killing (GO:0031342) | 5.06418760 |
| 12 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.06418760 |
| 13 | neutrophil activation involved in immune response (GO:0002283) | 5.00552242 |
| 14 | neutrophil mediated immunity (GO:0002446) | 4.70045889 |
| 15 | regulation of memory T cell differentiation (GO:0043380) | 4.49117288 |
| 16 | neutrophil activation (GO:0042119) | 4.48232251 |
| 17 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.46451814 |
| 18 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.36684263 |
| 19 | detection of molecule of bacterial origin (GO:0032490) | 4.32481279 |
| 20 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.29329667 |
| 21 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.18669450 |
| 22 | macrophage activation involved in immune response (GO:0002281) | 4.04561995 |
| 23 | leukocyte degranulation (GO:0043299) | 4.02478315 |
| 24 | regulation of gamma-delta T cell activation (GO:0046643) | 3.95967124 |
| 25 | mast cell degranulation (GO:0043303) | 3.95188213 |
| 26 | mast cell activation involved in immune response (GO:0002279) | 3.95188213 |
| 27 | positive regulation of B cell differentiation (GO:0045579) | 3.93607920 |
| 28 | regulation of B cell differentiation (GO:0045577) | 3.92615912 |
| 29 | * regulation of ARF GTPase activity (GO:0032312) | 3.90508948 |
| 30 | negative regulation of type 2 immune response (GO:0002829) | 3.90181644 |
| 31 | detection of other organism (GO:0098543) | 3.89955767 |
| 32 | granulocyte activation (GO:0036230) | 3.86202830 |
| 33 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.84659628 |
| 34 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 3.83982636 |
| 35 | response to interleukin-15 (GO:0070672) | 3.83807308 |
| 36 | myeloid leukocyte mediated immunity (GO:0002444) | 3.81383206 |
| 37 | myeloid cell activation involved in immune response (GO:0002275) | 3.80993421 |
| 38 | respiratory burst (GO:0045730) | 3.80701981 |
| 39 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.80543090 |
| 40 | microglial cell activation (GO:0001774) | 3.79222406 |
| 41 | cellular response to interleukin-15 (GO:0071350) | 3.77919340 |
| 42 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.77896176 |
| 43 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.76767659 |
| 44 | leukocyte aggregation (GO:0070486) | 3.75148049 |
| 45 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.74742093 |
| 46 | detection of external biotic stimulus (GO:0098581) | 3.74239941 |
| 47 | detection of bacterium (GO:0016045) | 3.54021026 |
| 48 | response to peptidoglycan (GO:0032494) | 3.53225784 |
| 49 | phosphatidylethanolamine metabolic process (GO:0046337) | 3.51887304 |
| 50 | mast cell activation (GO:0045576) | 3.50487212 |
| 51 | negative regulation of phagocytosis (GO:0050765) | 3.48989721 |
| 52 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.42817204 |
| 53 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.39202535 |
| 54 | response to host immune response (GO:0052572) | 3.33088355 |
| 55 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.33088355 |
| 56 | detection of biotic stimulus (GO:0009595) | 3.32895465 |
| 57 | B cell receptor signaling pathway (GO:0050853) | 3.30861726 |
| 58 | regulation of mast cell activation (GO:0033003) | 3.29374898 |
| 59 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.27138478 |
| 60 | macrophage activation (GO:0042116) | 3.24398941 |
| 61 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.21622822 |
| 62 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.21622822 |
| 63 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.21316300 |
| 64 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.19587567 |
| 65 | negative regulation of interleukin-12 production (GO:0032695) | 3.16425373 |
| 66 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.08817183 |
| 67 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.08817183 |
| 68 | negative regulation of interleukin-1 production (GO:0032692) | 3.03665419 |
| 69 | regulation of mast cell degranulation (GO:0043304) | 3.02944061 |
| 70 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.01102933 |
| 71 | dendritic cell chemotaxis (GO:0002407) | 3.00130394 |
| 72 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.00042520 |
| 73 | dendritic cell migration (GO:0036336) | 2.97364628 |
| 74 | activated T cell proliferation (GO:0050798) | 2.95573245 |
| 75 | positive regulation of mast cell activation (GO:0033005) | 2.95046453 |
| 76 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.94705571 |
| 77 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.93225175 |
| 78 | regulation of interleukin-13 production (GO:0032656) | 2.90350553 |
| 79 | regulation of regulatory T cell differentiation (GO:0045589) | 2.90290510 |
| 80 | response to type I interferon (GO:0034340) | 2.90284829 |
| 81 | cellular response to type I interferon (GO:0071357) | 2.89769107 |
| 82 | type I interferon signaling pathway (GO:0060337) | 2.89769107 |
| 83 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.88316785 |
| 84 | response to host (GO:0075136) | 2.87376832 |
| 85 | response to host defenses (GO:0052200) | 2.87376832 |
| 86 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.87376832 |
| 87 | positive regulation of granulocyte differentiation (GO:0030854) | 2.86801687 |
| 88 | negative thymic T cell selection (GO:0045060) | 2.86795824 |
| 89 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.81405481 |
| 90 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.80054689 |
| 91 | defense response to protozoan (GO:0042832) | 2.79611660 |
| 92 | negative regulation of T cell mediated immunity (GO:0002710) | 2.78484192 |
| 93 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.77289860 |
| 94 | negative T cell selection (GO:0043383) | 2.75235998 |
| 95 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.73876419 |
| 96 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.73120093 |
| 97 | regulation of T cell tolerance induction (GO:0002664) | 2.69931247 |
| 98 | regulation of tolerance induction (GO:0002643) | 2.69237534 |
| 99 | tolerance induction (GO:0002507) | 2.68655757 |
| 100 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.66319456 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.93940441 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.31514802 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.08557870 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.16064979 |
| 5 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.82099203 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.58749874 |
| 7 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.52656157 |
| 8 | MYB_26560356_Chip-Seq_TH2_Human | 2.52234080 |
| 9 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.47771637 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.32712005 |
| 11 | SPI1_23127762_ChIP-Seq_K562_Human | 2.27670433 |
| 12 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.25442912 |
| 13 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.24000413 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.20596849 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.13126196 |
| 16 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.00929158 |
| 17 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.00693380 |
| 18 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.97190503 |
| 19 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.95814484 |
| 20 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.93856653 |
| 21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.93366455 |
| 22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.92986183 |
| 23 | MYB_26560356_Chip-Seq_TH1_Human | 1.92069200 |
| 24 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.91924636 |
| 25 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.91725188 |
| 26 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.85069542 |
| 27 | UTX_26944678_Chip-Seq_JUKART_Human | 1.77805487 |
| 28 | GATA3_26560356_Chip-Seq_TH2_Human | 1.75100531 |
| 29 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.71905571 |
| 30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.68714534 |
| 31 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.68051958 |
| 32 | MAF_26560356_Chip-Seq_TH2_Human | 1.66272212 |
| 33 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63634252 |
| 34 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.63255635 |
| 35 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.60664802 |
| 36 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.60607385 |
| 37 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.57630825 |
| 38 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.57102115 |
| 39 | MAF_26560356_Chip-Seq_TH1_Human | 1.55419202 |
| 40 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.46182308 |
| 41 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.34472952 |
| 42 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33500274 |
| 43 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33014420 |
| 44 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.32648780 |
| 45 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.32592257 |
| 46 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.31329370 |
| 47 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.29778099 |
| 48 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.29717556 |
| 49 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.29190812 |
| 50 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.29042701 |
| 51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.28354094 |
| 52 | ERA_21632823_ChIP-Seq_H3396_Human | 1.27722408 |
| 53 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.27497840 |
| 54 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.25129561 |
| 55 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.23654186 |
| 56 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.23203050 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.21812780 |
| 58 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21463232 |
| 59 | VDR_22108803_ChIP-Seq_LS180_Human | 1.21015561 |
| 60 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.20306163 |
| 61 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.19006275 |
| 62 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.18982670 |
| 63 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.18303112 |
| 64 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.18052158 |
| 65 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.17494341 |
| 66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.17208036 |
| 67 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.17183408 |
| 68 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.17049596 |
| 69 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.16597915 |
| 70 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.15997685 |
| 71 | P300_27268052_Chip-Seq_Bcells_Human | 1.14927851 |
| 72 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13362566 |
| 73 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.12789468 |
| 74 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11898798 |
| 75 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.11898798 |
| 76 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.11564257 |
| 77 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.09256265 |
| 78 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.08961136 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.08930451 |
| 80 | GATA3_26560356_Chip-Seq_TH1_Human | 1.08377000 |
| 81 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.06867677 |
| 82 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05234949 |
| 83 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04246808 |
| 84 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04114104 |
| 85 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.03232632 |
| 86 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.00108643 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.98417299 |
| 88 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.98330665 |
| 89 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.97406749 |
| 90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.97318333 |
| 91 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.92822329 |
| 92 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.92011575 |
| 93 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91239085 |
| 94 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.90526998 |
| 95 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.88818184 |
| 96 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.88743152 |
| 97 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88613440 |
| 98 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.88005765 |
| 99 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.87835623 |
| 100 | RXR_22108803_ChIP-Seq_LS180_Human | 0.87769154 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.78640692 |
| 2 | MP0002132_abnormal_respiratory_system | 3.62378196 |
| 3 | MP0003436_decreased_susceptibility_to | 3.30332359 |
| 4 | MP0002419_abnormal_innate_immunity | 2.83180808 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.75915960 |
| 6 | MP0001800_abnormal_humoral_immune | 2.64005110 |
| 7 | MP0004381_abnormal_hair_follicle | 2.50968843 |
| 8 | MP0002396_abnormal_hematopoietic_system | 2.50489440 |
| 9 | MP0005025_abnormal_response_to | 2.46811796 |
| 10 | MP0005671_abnormal_response_to | 2.36257559 |
| 11 | MP0002420_abnormal_adaptive_immunity | 2.34826643 |
| 12 | MP0002723_abnormal_immune_serum | 2.32874624 |
| 13 | MP0001819_abnormal_immune_cell | 2.32361319 |
| 14 | MP0003303_peritoneal_inflammation | 2.29247041 |
| 15 | MP0005000_abnormal_immune_tolerance | 2.26257575 |
| 16 | MP0009785_altered_susceptibility_to | 2.23552840 |
| 17 | MP0005410_abnormal_fertilization | 2.23406854 |
| 18 | MP0003011_delayed_dark_adaptation | 2.14423168 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.12164313 |
| 20 | MP0002405_respiratory_system_inflammati | 1.92214431 |
| 21 | MP0003763_abnormal_thymus_physiology | 1.91535819 |
| 22 | MP0001790_abnormal_immune_system | 1.91336163 |
| 23 | MP0005387_immune_system_phenotype | 1.91336163 |
| 24 | MP0001986_abnormal_taste_sensitivity | 1.87445560 |
| 25 | MP0002277_abnormal_respiratory_mucosa | 1.86258023 |
| 26 | MP0009764_decreased_sensitivity_to | 1.82834796 |
| 27 | MP0002398_abnormal_bone_marrow | 1.80143229 |
| 28 | MP0000716_abnormal_immune_system | 1.79251851 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.76937160 |
| 30 | MP0000685_abnormal_immune_system | 1.76844917 |
| 31 | MP0003878_abnormal_ear_physiology | 1.76674082 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.76674082 |
| 33 | MP0009278_abnormal_bone_marrow | 1.76604055 |
| 34 | MP0002722_abnormal_immune_system | 1.69063084 |
| 35 | MP0002653_abnormal_ependyma_morphology | 1.66026136 |
| 36 | MP0003172_abnormal_lysosome_physiology | 1.65586346 |
| 37 | MP0000703_abnormal_thymus_morphology | 1.63091351 |
| 38 | MP0000689_abnormal_spleen_morphology | 1.61182535 |
| 39 | MP0003252_abnormal_bile_duct | 1.54333704 |
| 40 | MP0002148_abnormal_hypersensitivity_rea | 1.53762811 |
| 41 | MP0006035_abnormal_mitochondrial_morpho | 1.51359810 |
| 42 | MP0001845_abnormal_inflammatory_respons | 1.50759812 |
| 43 | MP0003866_abnormal_defecation | 1.49251015 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.49031782 |
| 45 | MP0003136_yellow_coat_color | 1.43715671 |
| 46 | MP0001533_abnormal_skeleton_physiology | 1.43113493 |
| 47 | MP0005397_hematopoietic_system_phenotyp | 1.41075508 |
| 48 | MP0001545_abnormal_hematopoietic_system | 1.41075508 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.39533166 |
| 50 | MP0002429_abnormal_blood_cell | 1.37541363 |
| 51 | MP0010155_abnormal_intestine_physiology | 1.30607949 |
| 52 | MP0003300_gastrointestinal_ulcer | 1.28773220 |
| 53 | MP0005174_abnormal_tail_pigmentation | 1.28274971 |
| 54 | MP0005084_abnormal_gallbladder_morpholo | 1.24800260 |
| 55 | MP0005464_abnormal_platelet_physiology | 1.24702852 |
| 56 | MP0005310_abnormal_salivary_gland | 1.14988829 |
| 57 | MP0008469_abnormal_protein_level | 1.13327762 |
| 58 | MP0004883_abnormal_blood_vessel | 1.12704602 |
| 59 | MP0003828_pulmonary_edema | 1.12317520 |
| 60 | MP0008004_abnormal_stomach_pH | 1.10696512 |
| 61 | MP0003183_abnormal_peptide_metabolism | 1.09196254 |
| 62 | MP0006082_CNS_inflammation | 1.07936557 |
| 63 | MP0008872_abnormal_physiological_respon | 1.04327325 |
| 64 | MP0009765_abnormal_xenobiotic_induced | 1.03208735 |
| 65 | MP0001968_abnormal_touch/_nociception | 1.03036089 |
| 66 | MP0003698_abnormal_male_reproductive | 0.98298384 |
| 67 | MP0004808_abnormal_hematopoietic_stem | 0.97141174 |
| 68 | MP0001929_abnormal_gametogenesis | 0.96819602 |
| 69 | MP0008260_abnormal_autophagy | 0.95290077 |
| 70 | MP0002102_abnormal_ear_morphology | 0.91665815 |
| 71 | MP0002693_abnormal_pancreas_physiology | 0.90853342 |
| 72 | MP0003787_abnormal_imprinting | 0.89747769 |
| 73 | MP0002928_abnormal_bile_duct | 0.87770173 |
| 74 | MP0003806_abnormal_nucleotide_metabolis | 0.86791186 |
| 75 | MP0001853_heart_inflammation | 0.85628660 |
| 76 | MP0004947_skin_inflammation | 0.84753968 |
| 77 | MP0005451_abnormal_body_composition | 0.84007784 |
| 78 | MP0006036_abnormal_mitochondrial_physio | 0.83224808 |
| 79 | MP0002736_abnormal_nociception_after | 0.82208054 |
| 80 | MP0008058_abnormal_DNA_repair | 0.81761388 |
| 81 | MP0003191_abnormal_cellular_cholesterol | 0.77934284 |
| 82 | MP0005248_abnormal_Harderian_gland | 0.75456446 |
| 83 | MP0004484_altered_response_of | 0.74956880 |
| 84 | MP0001501_abnormal_sleep_pattern | 0.74754571 |
| 85 | MP0001764_abnormal_homeostasis | 0.74642135 |
| 86 | MP0005164_abnormal_response_to | 0.73680321 |
| 87 | MP0002138_abnormal_hepatobiliary_system | 0.73116247 |
| 88 | MP0005376_homeostasis/metabolism_phenot | 0.67093409 |
| 89 | MP0001663_abnormal_digestive_system | 0.66212262 |
| 90 | MP0005166_decreased_susceptibility_to | 0.63714189 |
| 91 | MP0005319_abnormal_enzyme/_coenzyme | 0.62635047 |
| 92 | MP0001486_abnormal_startle_reflex | 0.59411608 |
| 93 | MP0004742_abnormal_vestibular_system | 0.56268752 |
| 94 | MP0009333_abnormal_splenocyte_physiolog | 0.56240872 |
| 95 | MP0008995_early_reproductive_senescence | 0.55776730 |
| 96 | MP0005551_abnormal_eye_electrophysiolog | 0.55607494 |
| 97 | MP0000015_abnormal_ear_pigmentation | 0.55542458 |
| 98 | MP0002019_abnormal_tumor_incidence | 0.55482511 |
| 99 | MP0001145_abnormal_male_reproductive | 0.54048399 |
| 100 | MP0009763_increased_sensitivity_to | 0.53304903 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myositis (HP:0100614) | 5.09994561 |
| 2 | Hypochromic microcytic anemia (HP:0004840) | 4.93610749 |
| 3 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.78114508 |
| 4 | Retrobulbar optic neuritis (HP:0100654) | 4.68974107 |
| 5 | Optic neuritis (HP:0100653) | 4.68974107 |
| 6 | Recurrent bacterial skin infections (HP:0005406) | 4.67566657 |
| 7 | Recurrent abscess formation (HP:0002722) | 4.65724385 |
| 8 | Orchitis (HP:0100796) | 4.61024534 |
| 9 | Stomatitis (HP:0010280) | 4.30405281 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.29960637 |
| 11 | Hypochromic anemia (HP:0001931) | 4.26111087 |
| 12 | Severe visual impairment (HP:0001141) | 4.23240294 |
| 13 | Eczematoid dermatitis (HP:0000976) | 4.07414749 |
| 14 | Encephalitis (HP:0002383) | 3.73272436 |
| 15 | Stomach cancer (HP:0012126) | 3.67683907 |
| 16 | Chronic obstructive pulmonary disease (HP:0006510) | 3.54708384 |
| 17 | Obstructive lung disease (HP:0006536) | 3.54708384 |
| 18 | Recurrent fungal infections (HP:0002841) | 3.40765948 |
| 19 | Panhypogammaglobulinemia (HP:0003139) | 3.39459221 |
| 20 | Granulocytopenia (HP:0001913) | 3.30915668 |
| 21 | Meningitis (HP:0001287) | 3.29382851 |
| 22 | Abnormality of macrophages (HP:0004311) | 3.24871521 |
| 23 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.24556224 |
| 24 | Keratoconjunctivitis sicca (HP:0001097) | 3.16949092 |
| 25 | Leukocytosis (HP:0001974) | 3.16772763 |
| 26 | Vasculitis (HP:0002633) | 3.14252670 |
| 27 | Eosinophilia (HP:0001880) | 3.13806159 |
| 28 | Gastrointestinal infarctions (HP:0005244) | 3.13181916 |
| 29 | Absent/shortened dynein arms (HP:0200106) | 3.13159686 |
| 30 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.13159686 |
| 31 | Recurrent skin infections (HP:0001581) | 3.04837392 |
| 32 | Keratoconjunctivitis (HP:0001096) | 2.92646836 |
| 33 | Abnormality of T cell physiology (HP:0011840) | 2.88423757 |
| 34 | Recurrent cutaneous fungal infections (HP:0011370) | 2.84790092 |
| 35 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.84790092 |
| 36 | Mediastinal lymphadenopathy (HP:0100721) | 2.84742705 |
| 37 | Chest pain (HP:0100749) | 2.76073500 |
| 38 | Abnormality of T cell number (HP:0011839) | 2.69560138 |
| 39 | Abnormality of B cell number (HP:0010975) | 2.69497614 |
| 40 | Autoimmune hemolytic anemia (HP:0001890) | 2.67099158 |
| 41 | Progressive cerebellar ataxia (HP:0002073) | 2.67004742 |
| 42 | Genetic anticipation (HP:0003743) | 2.66685696 |
| 43 | Abnormality of T cells (HP:0002843) | 2.63120361 |
| 44 | Hemoptysis (HP:0002105) | 2.62644254 |
| 45 | Spontaneous hematomas (HP:0007420) | 2.62160537 |
| 46 | Abnormality of eosinophils (HP:0001879) | 2.60171058 |
| 47 | Microcytic anemia (HP:0001935) | 2.56657204 |
| 48 | Autoimmune thrombocytopenia (HP:0001973) | 2.56649283 |
| 49 | Congenital stationary night blindness (HP:0007642) | 2.52077421 |
| 50 | Prolonged bleeding time (HP:0003010) | 2.50023388 |
| 51 | Increased IgM level (HP:0003496) | 2.41043350 |
| 52 | Urticaria (HP:0001025) | 2.37958612 |
| 53 | Recurrent sinusitis (HP:0011108) | 2.36839892 |
| 54 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.33621998 |
| 55 | Inflammation of the large intestine (HP:0002037) | 2.32099186 |
| 56 | Abnormality of the prostate (HP:0008775) | 2.31516584 |
| 57 | Attenuation of retinal blood vessels (HP:0007843) | 2.28466597 |
| 58 | Slow saccadic eye movements (HP:0000514) | 2.27109772 |
| 59 | Increased IgE level (HP:0003212) | 2.26512199 |
| 60 | Gingivitis (HP:0000230) | 2.24762209 |
| 61 | Abnormal ciliary motility (HP:0012262) | 2.24313851 |
| 62 | Arterial thrombosis (HP:0004420) | 2.23754065 |
| 63 | Episodic fever (HP:0001954) | 2.20356271 |
| 64 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.18545748 |
| 65 | Pulmonary embolism (HP:0002204) | 2.17290788 |
| 66 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.16511654 |
| 67 | Gastrointestinal inflammation (HP:0004386) | 2.13036942 |
| 68 | Anorexia (HP:0002039) | 2.12761112 |
| 69 | Pustule (HP:0200039) | 2.09327859 |
| 70 | Lymphopenia (HP:0001888) | 2.08947304 |
| 71 | Postural instability (HP:0002172) | 2.08542350 |
| 72 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.06034197 |
| 73 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.06034197 |
| 74 | Prostate neoplasm (HP:0100787) | 2.05866354 |
| 75 | Peritonitis (HP:0002586) | 2.03765192 |
| 76 | Pancreatic cysts (HP:0001737) | 2.00986840 |
| 77 | T lymphocytopenia (HP:0005403) | 1.99202252 |
| 78 | Abnormality of the pleura (HP:0002103) | 1.97199573 |
| 79 | Pulmonary infiltrates (HP:0002113) | 1.95878813 |
| 80 | True hermaphroditism (HP:0010459) | 1.95651080 |
| 81 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.93969227 |
| 82 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.93882004 |
| 83 | Abnormality of DNA repair (HP:0003254) | 1.91886239 |
| 84 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.89434704 |
| 85 | Abnormality of the columella (HP:0009929) | 1.89306641 |
| 86 | Gangrene (HP:0100758) | 1.88106480 |
| 87 | Gingival bleeding (HP:0000225) | 1.87032331 |
| 88 | Abnormality of male internal genitalia (HP:0000022) | 1.86982755 |
| 89 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.81265343 |
| 90 | Sepsis (HP:0100806) | 1.80704835 |
| 91 | Pendular nystagmus (HP:0012043) | 1.79498376 |
| 92 | Recurrent viral infections (HP:0004429) | 1.77358435 |
| 93 | Epistaxis (HP:0000421) | 1.77255228 |
| 94 | IgM deficiency (HP:0002850) | 1.75946574 |
| 95 | Gaze-evoked nystagmus (HP:0000640) | 1.75748993 |
| 96 | Cellulitis (HP:0100658) | 1.74427609 |
| 97 | Petechiae (HP:0000967) | 1.73905575 |
| 98 | Tetany (HP:0001281) | 1.71582491 |
| 99 | Severe combined immunodeficiency (HP:0004430) | 1.71193228 |
| 100 | Papilledema (HP:0001085) | 1.68276193 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 4.12507605 |
| 2 | RIPK4 | 3.86151316 |
| 3 | PINK1 | 3.54845740 |
| 4 | IRAK4 | 3.31241798 |
| 5 | TNK2 | 3.01589469 |
| 6 | MAP4K1 | 2.81355794 |
| 7 | TAOK3 | 2.70521622 |
| 8 | MAP2K3 | 2.65335908 |
| 9 | TXK | 2.46189611 |
| 10 | INSRR | 2.35612354 |
| 11 | GRK6 | 2.24832768 |
| 12 | BLK | 2.16887003 |
| 13 | BTK | 1.94058411 |
| 14 | CSK | 1.91582119 |
| 15 | TNIK | 1.81666672 |
| 16 | NLK | 1.79047941 |
| 17 | FES | 1.77460104 |
| 18 | MARK3 | 1.67327803 |
| 19 | FRK | 1.63369818 |
| 20 | MAP4K2 | 1.58091009 |
| 21 | HCK | 1.57490037 |
| 22 | MAP3K7 | 1.48408448 |
| 23 | TYK2 | 1.44897307 |
| 24 | EPHB1 | 1.44799644 |
| 25 | OXSR1 | 1.40265070 |
| 26 | SYK | 1.36152069 |
| 27 | ITK | 1.35878413 |
| 28 | JAK2 | 1.33256619 |
| 29 | ZAP70 | 1.30625249 |
| 30 | MAP3K3 | 1.25559490 |
| 31 | TEC | 1.22525244 |
| 32 | ERN1 | 1.21889274 |
| 33 | TAOK1 | 1.21427161 |
| 34 | MAP3K1 | 1.20201559 |
| 35 | SIK3 | 1.19669592 |
| 36 | JAK3 | 1.17865754 |
| 37 | LYN | 1.17351112 |
| 38 | PASK | 1.15017411 |
| 39 | KSR2 | 1.11027360 |
| 40 | STK38 | 1.09521393 |
| 41 | FGR | 1.05760869 |
| 42 | YES1 | 1.05738229 |
| 43 | PIK3CG | 1.02061843 |
| 44 | NUAK1 | 0.99852828 |
| 45 | PDK1 | 0.94790109 |
| 46 | MAP2K6 | 0.94333320 |
| 47 | BMPR1B | 0.90512317 |
| 48 | PRKD2 | 0.88940084 |
| 49 | MAP3K11 | 0.88887008 |
| 50 | PRKCQ | 0.88099573 |
| 51 | KIT | 0.87035037 |
| 52 | LCK | 0.86933284 |
| 53 | DAPK2 | 0.84705214 |
| 54 | PDPK1 | 0.84060706 |
| 55 | DYRK3 | 0.83920511 |
| 56 | MARK2 | 0.83883775 |
| 57 | SIK2 | 0.82589266 |
| 58 | PTK2B | 0.80797369 |
| 59 | IRAK1 | 0.80197490 |
| 60 | IKBKE | 0.79798911 |
| 61 | NME1 | 0.77593092 |
| 62 | STK11 | 0.75827361 |
| 63 | MATK | 0.70738296 |
| 64 | ADRBK2 | 0.65075664 |
| 65 | CSF1R | 0.64171190 |
| 66 | PLK4 | 0.63637987 |
| 67 | IRAK2 | 0.58885549 |
| 68 | GRK1 | 0.57941437 |
| 69 | CAMKK1 | 0.54145603 |
| 70 | WNK3 | 0.53778928 |
| 71 | RAF1 | 0.53116687 |
| 72 | WNK1 | 0.52959334 |
| 73 | STK10 | 0.51459945 |
| 74 | ALK | 0.48446120 |
| 75 | KSR1 | 0.45810058 |
| 76 | MAPK13 | 0.45700954 |
| 77 | CAMKK2 | 0.45262172 |
| 78 | PAK3 | 0.45098363 |
| 79 | CAMK1 | 0.43830164 |
| 80 | FYN | 0.43630105 |
| 81 | STK38L | 0.43561595 |
| 82 | BRD4 | 0.43306491 |
| 83 | DYRK1B | 0.40914059 |
| 84 | PRKG2 | 0.40804414 |
| 85 | ACVR1B | 0.40451742 |
| 86 | PKN2 | 0.40053006 |
| 87 | PTK6 | 0.36973876 |
| 88 | MAP3K2 | 0.36518079 |
| 89 | TGFBR2 | 0.35462815 |
| 90 | PRKCZ | 0.34788851 |
| 91 | PRKAA2 | 0.34295005 |
| 92 | IKBKB | 0.33860811 |
| 93 | MAP2K4 | 0.33602834 |
| 94 | RET | 0.33532751 |
| 95 | MAP3K5 | 0.33190019 |
| 96 | DYRK2 | 0.32842799 |
| 97 | MAP2K2 | 0.31688848 |
| 98 | FLT3 | 0.30723636 |
| 99 | CAMK4 | 0.28735133 |
| 100 | MAPK12 | 0.25815350 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.67435067 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.64174449 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.57127379 |
| 4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.49510652 |
| 5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.23468294 |
| 6 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.23409804 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.13200367 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.03604374 |
| 9 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.98443127 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.94387296 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 1.93808048 |
| 12 | Tuberculosis_Homo sapiens_hsa05152 | 1.92744948 |
| 13 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.84204177 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.82531702 |
| 15 | Olfactory transduction_Homo sapiens_hsa04740 | 1.79954497 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.76646566 |
| 17 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.73841464 |
| 18 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.71948196 |
| 19 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.71149440 |
| 20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.67838471 |
| 21 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.67319166 |
| 22 | Malaria_Homo sapiens_hsa05144 | 1.60672681 |
| 23 | Measles_Homo sapiens_hsa05162 | 1.60048736 |
| 24 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.51870661 |
| 25 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.46849871 |
| 26 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.46479240 |
| 27 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.37931084 |
| 28 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.36969796 |
| 29 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.36420946 |
| 30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.32654870 |
| 31 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.32515758 |
| 32 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.29286689 |
| 33 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.28149289 |
| 34 | Influenza A_Homo sapiens_hsa05164 | 1.26408483 |
| 35 | Platelet activation_Homo sapiens_hsa04611 | 1.23949089 |
| 36 | Phototransduction_Homo sapiens_hsa04744 | 1.20554049 |
| 37 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.20211932 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.18112520 |
| 39 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.16718076 |
| 40 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.11930960 |
| 41 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.05419854 |
| 42 | Phagosome_Homo sapiens_hsa04145 | 1.04027081 |
| 43 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.97132793 |
| 44 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.95161743 |
| 45 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.92952541 |
| 46 | Legionellosis_Homo sapiens_hsa05134 | 0.90959787 |
| 47 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.88834589 |
| 48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85854661 |
| 49 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.85105593 |
| 50 | Hepatitis B_Homo sapiens_hsa05161 | 0.83121211 |
| 51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.82568622 |
| 52 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.81762976 |
| 53 | Viral myocarditis_Homo sapiens_hsa05416 | 0.81531550 |
| 54 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.80723580 |
| 55 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.79353476 |
| 56 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.79204633 |
| 57 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.77334433 |
| 58 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.76751544 |
| 59 | Base excision repair_Homo sapiens_hsa03410 | 0.75161564 |
| 60 | Apoptosis_Homo sapiens_hsa04210 | 0.75101903 |
| 61 | Hepatitis C_Homo sapiens_hsa05160 | 0.74452404 |
| 62 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.72786086 |
| 63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67730759 |
| 64 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.67061610 |
| 65 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.66751153 |
| 66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.66008180 |
| 67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.65326049 |
| 68 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.64932662 |
| 69 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.64669889 |
| 70 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.63036471 |
| 71 | ABC transporters_Homo sapiens_hsa02010 | 0.62462543 |
| 72 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.61351070 |
| 73 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56911707 |
| 74 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.56254726 |
| 75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.56124932 |
| 76 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.54405905 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.51969125 |
| 78 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.50701637 |
| 79 | Endometrial cancer_Homo sapiens_hsa05213 | 0.49968363 |
| 80 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.49135446 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.48634040 |
| 82 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.48198115 |
| 83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.47851794 |
| 84 | Homologous recombination_Homo sapiens_hsa03440 | 0.47261902 |
| 85 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.47122096 |
| 86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.46539765 |
| 87 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.45514708 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.45456651 |
| 89 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.42958836 |
| 90 | Colorectal cancer_Homo sapiens_hsa05210 | 0.42734397 |
| 91 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.41849295 |
| 92 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.41611940 |
| 93 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.40686654 |
| 94 | Endocytosis_Homo sapiens_hsa04144 | 0.40251936 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.39875295 |
| 96 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.39169209 |
| 97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.37767187 |
| 98 | Asthma_Homo sapiens_hsa05310 | 0.37522207 |
| 99 | Insulin resistance_Homo sapiens_hsa04931 | 0.35799085 |
| 100 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.35794644 |

