AGBL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.70698219
2epithelial cilium movement (GO:0003351)8.69304600
3piRNA metabolic process (GO:0034587)8.49400075
4cilium movement (GO:0003341)8.33909298
5sperm motility (GO:0030317)8.26778427
6multicellular organism reproduction (GO:0032504)8.20150926
7fusion of sperm to egg plasma membrane (GO:0007342)8.14263279
8motile cilium assembly (GO:0044458)7.77253744
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.57936742
10sperm-egg recognition (GO:0035036)7.44342098
11acrosome reaction (GO:0007340)7.23911660
12acrosome assembly (GO:0001675)7.20668369
13male meiosis (GO:0007140)6.91078380
14binding of sperm to zona pellucida (GO:0007339)6.70461548
15cell-cell recognition (GO:0009988)6.64214409
16reproduction (GO:0000003)6.44096735
17spermatid development (GO:0007286)6.34804003
18microtubule bundle formation (GO:0001578)6.19635011
19regulation of cilium movement (GO:0003352)6.15279566
20synaptonemal complex organization (GO:0070193)6.14380766
21plasma membrane fusion (GO:0045026)6.13729813
22cell wall macromolecule metabolic process (GO:0044036)6.03030438
23cell wall macromolecule catabolic process (GO:0016998)6.03030438
24DNA methylation involved in gamete generation (GO:0043046)5.94761647
25synaptonemal complex assembly (GO:0007130)5.82622645
26single fertilization (GO:0007338)5.56239632
27primary alcohol catabolic process (GO:0034310)5.32934305
28vitamin transmembrane transport (GO:0035461)5.27502797
29male meiosis I (GO:0007141)5.08940819
30intraciliary transport (GO:0042073)5.05932730
31ventricular system development (GO:0021591)5.01829648
32centriole assembly (GO:0098534)4.95383927
33microtubule depolymerization (GO:0007019)4.93205012
34sperm capacitation (GO:0048240)4.81046178
35chromosome organization involved in meiosis (GO:0070192)4.80483370
36axoneme assembly (GO:0035082)4.78438959
37ethanol metabolic process (GO:0006067)4.75946804
38fertilization (GO:0009566)4.67787847
39spermatogenesis (GO:0007283)4.37886818
40male gamete generation (GO:0048232)4.37236353
41glomerular epithelial cell development (GO:0072310)4.32614018
42response to xenobiotic stimulus (GO:0009410)4.30807236
43diterpenoid biosynthetic process (GO:0016102)4.29123428
44negative regulation of T cell differentiation in thymus (GO:0033085)4.28030091
45meiotic cell cycle (GO:0051321)4.26037855
46regulation of interleukin-5 production (GO:0032674)4.13985469
47meiotic nuclear division (GO:0007126)4.13167780
48centriole replication (GO:0007099)4.12898351
49gamete generation (GO:0007276)4.07872681
50cilium organization (GO:0044782)4.06051976
51cilium assembly (GO:0042384)3.96878606
52pyrimidine-containing compound transmembrane transport (GO:0072531)3.95384961
53left/right axis specification (GO:0070986)3.94615288
54meiosis I (GO:0007127)3.93708159
55synapsis (GO:0007129)3.91313077
56tolerance induction (GO:0002507)3.91170756
57protein localization to cilium (GO:0061512)3.90202244
58germ cell development (GO:0007281)3.81696924
59cellular process involved in reproduction in multicellular organism (GO:0022412)3.76749234
60lateral ventricle development (GO:0021670)3.70625056
61exogenous drug catabolic process (GO:0042738)3.67503750
62regulation of germinal center formation (GO:0002634)3.58850662
63regulation of meiosis I (GO:0060631)3.55917167
64left/right pattern formation (GO:0060972)3.54281548
65lung epithelium development (GO:0060428)3.53073664
66establishment of apical/basal cell polarity (GO:0035089)3.52190501
67regulation of interleukin-13 production (GO:0032656)3.50416600
68phosphatidylethanolamine biosynthetic process (GO:0006646)3.50018023
69ethanol oxidation (GO:0006069)3.46170338
70negative regulation of inclusion body assembly (GO:0090084)3.36747365
71retinoic acid metabolic process (GO:0042573)3.32161211
72negative regulation of B cell mediated immunity (GO:0002713)3.31479905
73negative regulation of immunoglobulin mediated immune response (GO:0002890)3.31479905
74phosphatidylethanolamine metabolic process (GO:0046337)3.29976758
75cellular component assembly involved in morphogenesis (GO:0010927)3.29883043
76organic cation transport (GO:0015695)3.27658789
77negative regulation of humoral immune response (GO:0002921)3.26224543
78terpenoid biosynthetic process (GO:0016114)3.25408887
79retinal rod cell development (GO:0046548)3.24520367
80photoreceptor cell maintenance (GO:0045494)3.23025607
81microtubule severing (GO:0051013)3.21811207
82cilium morphogenesis (GO:0060271)3.21642450
83determination of left/right symmetry (GO:0007368)3.21084642
84drug catabolic process (GO:0042737)3.20552275
85smoothened signaling pathway (GO:0007224)3.17940161
86establishment of monopolar cell polarity (GO:0061162)3.16412132
87establishment or maintenance of monopolar cell polarity (GO:0061339)3.16412132
88multicellular organismal reproductive process (GO:0048609)3.14896069
89replicative senescence (GO:0090399)3.13575349
90protein K11-linked deubiquitination (GO:0035871)3.11131205
91meiotic cell cycle process (GO:1903046)3.10873041
92regulation of centriole replication (GO:0046599)3.09439965
93protein polyglutamylation (GO:0018095)3.06720699
94determination of bilateral symmetry (GO:0009855)3.02354951
95cytoplasmic microtubule organization (GO:0031122)3.00886901
96cell recognition (GO:0008037)3.00709747
97phosphatidylcholine biosynthetic process (GO:0006656)3.00499536
98retinal cone cell development (GO:0046549)2.97420893
99seminiferous tubule development (GO:0072520)2.94955555
100glutathione derivative biosynthetic process (GO:1901687)2.94775423
101glutathione derivative metabolic process (GO:1901685)2.94775423
102specification of symmetry (GO:0009799)2.94330072
103calcium ion-dependent exocytosis (GO:0017156)2.93900994
104monoubiquitinated protein deubiquitination (GO:0035520)2.91321347
105spinal cord motor neuron differentiation (GO:0021522)2.88251701
106cellular ketone body metabolic process (GO:0046950)2.87474163
107positive regulation of tolerance induction (GO:0002645)2.86046451
108cellular response to gamma radiation (GO:0071480)2.81041008
109nonmotile primary cilium assembly (GO:0035058)2.80465522
110microtubule-based movement (GO:0007018)2.80363700
111protein K6-linked ubiquitination (GO:0085020)2.77770803
112organelle assembly (GO:0070925)2.73998018
113regulation of microtubule-based movement (GO:0060632)2.73901995
114sequestering of actin monomers (GO:0042989)2.73861410
115spermatid nucleus differentiation (GO:0007289)2.73675899
116retinol metabolic process (GO:0042572)2.69770046
117DNA synthesis involved in DNA repair (GO:0000731)2.68724214
118nucleoside diphosphate phosphorylation (GO:0006165)2.65487909
119regulation of spindle checkpoint (GO:0090231)2.65409024
120establishment of tissue polarity (GO:0007164)2.65400116
121establishment of planar polarity (GO:0001736)2.65400116
122O-glycan processing (GO:0016266)2.65343032
123microtubule-based process (GO:0007017)2.64915390
124primary alcohol metabolic process (GO:0034308)2.64328402
125carnitine metabolic process (GO:0009437)2.62679456
126nuclear pore complex assembly (GO:0051292)2.60774552
127superoxide anion generation (GO:0042554)2.59173141
128gene silencing by RNA (GO:0031047)2.59045920
129aldehyde catabolic process (GO:0046185)2.57832751
130single strand break repair (GO:0000012)2.57765582
131excretion (GO:0007588)2.56173303
132regulation of inclusion body assembly (GO:0090083)2.55830584
133reciprocal DNA recombination (GO:0035825)2.54239116
134reciprocal meiotic recombination (GO:0007131)2.54239116
135sister chromatid cohesion (GO:0007062)2.53573578
136one-carbon compound transport (GO:0019755)2.53254447
137positive regulation of smoothened signaling pathway (GO:0045880)2.52591657
138multicellular organismal development (GO:0007275)2.52516519
139rRNA catabolic process (GO:0016075)2.52487652
140microtubule polymerization or depolymerization (GO:0031109)2.52346280
141ketone body metabolic process (GO:1902224)2.51954984
142establishment of protein localization to Golgi (GO:0072600)2.51147149
143negative regulation of skeletal muscle tissue development (GO:0048642)2.50604375
144sialylation (GO:0097503)2.47367821
145cornea development in camera-type eye (GO:0061303)2.47181341
146intra-S DNA damage checkpoint (GO:0031573)2.45407157
147DNA methylation (GO:0006306)2.44971109
148DNA alkylation (GO:0006305)2.44971109
149protein targeting to Golgi (GO:0000042)2.44820729
150response to X-ray (GO:0010165)2.44596016
151poly(A)+ mRNA export from nucleus (GO:0016973)2.43294441
152regulation of collateral sprouting (GO:0048670)2.41619362
153lactate metabolic process (GO:0006089)2.41495402
154cell projection assembly (GO:0030031)2.40588272
155DNA double-strand break processing (GO:0000729)2.39054240
156appendage development (GO:0048736)2.38419469
157limb development (GO:0060173)2.38419469
158genitalia morphogenesis (GO:0035112)2.38331316
159meiotic chromosome segregation (GO:0045132)2.36979961
160regulation of chromatin binding (GO:0035561)2.36595207
161regulation of protein polyubiquitination (GO:1902914)2.35715865
162cilium or flagellum-dependent cell motility (GO:0001539)12.6470899

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.48454180
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.37045437
3EZH2_22144423_ChIP-Seq_EOC_Human3.77755949
4FLI1_27457419_Chip-Seq_LIVER_Mouse3.32740130
5PCGF2_27294783_Chip-Seq_ESCs_Mouse3.31514788
6DROSHA_22980978_ChIP-Seq_HELA_Human2.86820933
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.79506474
8SUZ12_27294783_Chip-Seq_NPCs_Mouse2.63068507
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.61788871
10PCGF2_27294783_Chip-Seq_NPCs_Mouse2.61619792
11NFE2_27457419_Chip-Seq_LIVER_Mouse2.59903402
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.52082135
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.38909994
14FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.33526250
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.13930189
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.12920228
17ZNF274_21170338_ChIP-Seq_K562_Hela2.12404205
18EZH2_27294783_Chip-Seq_NPCs_Mouse2.04627379
19TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse2.02413615
20EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.97980704
21GBX2_23144817_ChIP-Seq_PC3_Human1.94124029
22* STAT3_18555785_Chip-Seq_ESCs_Mouse1.91402760
23NANOG_18555785_Chip-Seq_ESCs_Mouse1.91365942
24P53_22387025_ChIP-Seq_ESCs_Mouse1.90920887
25SUZ12_18555785_Chip-Seq_ESCs_Mouse1.83206076
26KAP1_22055183_ChIP-Seq_ESCs_Mouse1.82582611
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.81860966
28EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.76795028
29VDR_22108803_ChIP-Seq_LS180_Human1.76453626
30OCT4_18555785_Chip-Seq_ESCs_Mouse1.75261297
31E2F1_18555785_Chip-Seq_ESCs_Mouse1.74449911
32NMYC_18555785_Chip-Seq_ESCs_Mouse1.72246943
33P300_18555785_Chip-Seq_ESCs_Mouse1.71432332
34CMYC_18555785_Chip-Seq_ESCs_Mouse1.71038251
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69408001
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.67244768
37TAL1_26923725_Chip-Seq_HPCs_Mouse1.66482233
38* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.65644407
39KLF4_18555785_Chip-Seq_ESCs_Mouse1.64196779
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.63957531
41CRX_20693478_ChIP-Seq_RETINA_Mouse1.63736905
42* BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.61565393
43ZFX_18555785_Chip-Seq_ESCs_Mouse1.61184644
44* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.59542589
45* PU1_27457419_Chip-Seq_LIVER_Mouse1.58950497
46SOX2_18555785_Chip-Seq_ESCs_Mouse1.57760783
47EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.57672623
48MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.55930507
49ARNT_22903824_ChIP-Seq_MCF-7_Human1.55824484
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.54140653
51RNF2_27304074_Chip-Seq_NSC_Mouse1.53730821
52FOXA1_25329375_ChIP-Seq_VCAP_Human1.53447735
53FOXA1_27270436_Chip-Seq_PROSTATE_Human1.53447735
54CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.52942353
55OCT4_21477851_ChIP-Seq_ESCs_Mouse1.52035790
56TDRD3_21172665_ChIP-Seq_MCF-7_Human1.51625412
57MYC_19829295_ChIP-Seq_ESCs_Human1.50503298
58CTCF_18555785_Chip-Seq_ESCs_Mouse1.49251250
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46728473
60SMAD1_18555785_Chip-Seq_ESCs_Mouse1.45950388
61RBPJ_21746931_ChIP-Seq_IB4_Human1.45572358
62HNFA_21074721_ChIP-Seq_CACO-2_Human1.45123234
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45061645
64AHR_22903824_ChIP-Seq_MCF-7_Human1.43769070
65GATA1_26923725_Chip-Seq_HPCs_Mouse1.42907622
66CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.42843985
67STAT1_17558387_ChIP-Seq_HELA_Human1.42700114
68PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.42660849
69ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.41968602
70STAT1_20625510_ChIP-Seq_HELA_Human1.37692055
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37146481
72SMRT_27268052_Chip-Seq_Bcells_Human1.36511094
73* SMAD4_21741376_ChIP-Seq_EPCs_Human1.35491141
74BCAT_22108803_ChIP-Seq_LS180_Human1.35327798
75* EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.34395599
76YY1_22570637_ChIP-Seq_MALME-3M_Human1.32388090
77CBX2_22325352_ChIP-Seq_293T-Rex_Human1.32284668
78BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31793986
79TP53_18474530_ChIP-ChIP_U2OS_Human1.31724024
80AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.31625662
81FOXM1_26456572_ChIP-Seq_MCF-7_Human1.31481216
82ERA_21632823_ChIP-Seq_H3396_Human1.30981837
83ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.30327012
84SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.30035264
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.29550318
86CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.29512181
87VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.29430646
88GATA6_21074721_ChIP-Seq_CACO-2_Human1.29258740
89* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.28756254
90KDM2B_26808549_Chip-Seq_REH_Human1.28411349
91* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.28405906
92TP63_23658742_ChIP-Seq_EP156T_Human1.27598231
93POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27260563
94TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27260563
95RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.26819475
96NCOR_22424771_ChIP-Seq_293T_Human1.26631789
97GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.26428261
98AR_21572438_ChIP-Seq_LNCaP_Human1.26049792
99AR_20517297_ChIP-Seq_VCAP_Human1.25934985
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.25900340
101CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.25568041
102ERG_20517297_ChIP-Seq_VCAP_Human1.25304883
103ER_23166858_ChIP-Seq_MCF-7_Human1.24709631
104CTCF_20526341_ChIP-Seq_ESCs_Human1.24498424
105CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24103478
106OCT4_20526341_ChIP-Seq_ESCs_Human1.23597420
107SMAD4_21799915_ChIP-Seq_A2780_Human1.23299331
108NANOG_20526341_ChIP-Seq_ESCs_Human1.22867006
109NFYA_21822215_ChIP-Seq_K562_Human1.21644250
110* SMAD3_21741376_ChIP-Seq_EPCs_Human1.21585469
111FOXA1_21572438_ChIP-Seq_LNCaP_Human1.21531909
112TCF4_22108803_ChIP-Seq_LS180_Human1.21003906
113* CEBPB_22108803_ChIP-Seq_LS180_Human1.20441607
114IRF8_21731497_ChIP-ChIP_J774_Mouse1.19710978
115FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.19307395
116ELF1_20517297_ChIP-Seq_JURKAT_Human1.19215560
117PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.18355504
118TCF4_23295773_ChIP-Seq_U87_Human1.18259602
119TAF2_19829295_ChIP-Seq_ESCs_Human1.18121843
120* GATA3_21878914_ChIP-Seq_MCF-7_Human1.17851609
121TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.17616238
122CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.16866236
123SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.16630826
124SALL1_21062744_ChIP-ChIP_HESCs_Human1.15951105
125AR_25329375_ChIP-Seq_VCAP_Human1.15944351
126ESR1_20079471_ChIP-ChIP_T-47D_Human1.15682172
127P300_27268052_Chip-Seq_Bcells_Human1.15530891
128AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15394048
129HOXB7_26014856_ChIP-Seq_BT474_Human1.15103991
130E2F1_20622854_ChIP-Seq_HELA_Human1.15091346
131TP63_22573176_ChIP-Seq_HFKS_Human1.13270088
132GF1_26923725_Chip-Seq_HPCs_Mouse1.12453318
133EWS_26573619_Chip-Seq_HEK293_Human1.11205568
134RUNX2_22187159_ChIP-Seq_PCA_Human1.11036828
135ELK4_26923725_Chip-Seq_MESODERM_Mouse1.09594139
136* SMC4_20622854_ChIP-Seq_HELA_Human1.09316633
137* PHF8_20622854_ChIP-Seq_HELA_Human1.09293073
138CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08448338
139CTCF_27219007_Chip-Seq_Bcells_Human1.07484410
140CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07424116
141P300_19829295_ChIP-Seq_ESCs_Human1.06913742
142PRDM14_20953172_ChIP-Seq_ESCs_Human1.06646449
143RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.06343085
144EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.05283445
145LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04538815
146PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03765474
147FUS_26573619_Chip-Seq_HEK293_Human1.03268898
148TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02494193
149TAF15_26573619_Chip-Seq_HEK293_Human1.01588905
150TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.01577606
151IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00922990
152CBP_20019798_ChIP-Seq_JUKART_Human1.00922990
153CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98563952
154WDR5_24793694_ChIP-Seq_LNCAP_Human0.97807944
155GF1B_26923725_Chip-Seq_HPCs_Mouse0.97559361
156EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97004935
157RUNX1_26923725_Chip-Seq_HPCs_Mouse0.96353400
158IRF8_22096565_ChIP-ChIP_GC-B_Human0.95860678
159NR3C1_21868756_ChIP-Seq_MCF10A_Human0.94900748
160MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94312402
161STAT3_23295773_ChIP-Seq_U87_Human0.94038519
162NFYB_21822215_ChIP-Seq_K562_Human0.93142300
163TBL1_22424771_ChIP-Seq_293T_Human0.91149602
164RBPJ_22232070_ChIP-Seq_NCS_Mouse0.90795746
165ETV1_20927104_ChIP-Seq_GIST48_Human0.90542864
166SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.87170363
167TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86965102
168GATA3_21867929_ChIP-Seq_TH1_Mouse0.86925721
169RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.86877362
170PHF8_20622853_ChIP-Seq_HELA_Human0.85924777
171TP63_19390658_ChIP-ChIP_HaCaT_Human0.85675373
172* GATA3_21867929_ChIP-Seq_CD8_Mouse0.84930331

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.76206325
2MP0008875_abnormal_xenobiotic_pharmacok5.90981079
3MP0008877_abnormal_DNA_methylation4.06578085
4MP0003698_abnormal_male_reproductive3.77655606
5MP0001929_abnormal_gametogenesis3.56984890
6MP0004043_abnormal_pH_regulation3.28354406
7MP0002210_abnormal_sex_determination2.93338543
8MP0008058_abnormal_DNA_repair2.90444242
9MP0008057_abnormal_DNA_replication2.69043767
10MP0001984_abnormal_olfaction2.52616711
11MP0002160_abnormal_reproductive_system2.45334671
12MP0006292_abnormal_olfactory_placode2.43630640
13MP0000566_synostosis2.33289325
14MP0002653_abnormal_ependyma_morphology2.29367708
15MP0001188_hyperpigmentation2.25782551
16MP0009780_abnormal_chondrocyte_physiolo2.20851587
17MP0001145_abnormal_male_reproductive2.19558018
18MP0002132_abnormal_respiratory_system2.14132489
19MP0000653_abnormal_sex_gland2.06248558
20MP0000569_abnormal_digit_pigmentation2.06045713
21MP0002282_abnormal_trachea_morphology2.01498708
22MP0005083_abnormal_biliary_tract1.93508520
23MP0001485_abnormal_pinna_reflex1.93163126
24MP0002161_abnormal_fertility/fecundity1.91951093
25MP0001765_abnormal_ion_homeostasis1.89826056
26MP0008007_abnormal_cellular_replicative1.89562558
27MP0005646_abnormal_pituitary_gland1.89019407
28MP0004019_abnormal_vitamin_homeostasis1.86619565
29MP0004782_abnormal_surfactant_physiolog1.73630512
30MP0000015_abnormal_ear_pigmentation1.70388004
31MP0002102_abnormal_ear_morphology1.69804884
32MP0000383_abnormal_hair_follicle1.68977800
33MP0009697_abnormal_copulation1.68474267
34MP0003195_calcinosis1.66711778
35MP0003786_premature_aging1.65415210
36MP0010094_abnormal_chromosome_stability1.65305829
37MP0002735_abnormal_chemical_nociception1.61933398
38MP0005389_reproductive_system_phenotype1.59804149
39MP0002277_abnormal_respiratory_mucosa1.58156801
40MP0008789_abnormal_olfactory_epithelium1.55413592
41MP0008995_early_reproductive_senescence1.50599653
42MP0003136_yellow_coat_color1.49852316
43MP0000678_abnormal_parathyroid_gland1.43091830
44MP0005365_abnormal_bile_salt1.42783135
45MP0005499_abnormal_olfactory_system1.40803474
46MP0005394_taste/olfaction_phenotype1.40803474
47MP0005636_abnormal_mineral_homeostasis1.36351185
48MP0001835_abnormal_antigen_presentation1.30769745
49MP0002876_abnormal_thyroid_physiology1.30329817
50MP0005310_abnormal_salivary_gland1.30234280
51MP0002909_abnormal_adrenal_gland1.29617469
52MP0005645_abnormal_hypothalamus_physiol1.27895574
53MP0008872_abnormal_physiological_respon1.25615783
54MP0003878_abnormal_ear_physiology1.25545199
55MP0005377_hearing/vestibular/ear_phenot1.25545199
56MP0005647_abnormal_sex_gland1.24273209
57MP0005075_abnormal_melanosome_morpholog1.23536086
58MP0002163_abnormal_gland_morphology1.22059666
59MP0010678_abnormal_skin_adnexa1.21927035
60MP0001119_abnormal_female_reproductive1.21798476
61MP0005171_absent_coat_pigmentation1.19599592
62MP0003941_abnormal_skin_development1.19570165
63MP0003111_abnormal_nucleus_morphology1.17836635
64MP0005395_other_phenotype1.15891893
65MP0001968_abnormal_touch/_nociception1.12429588
66MP0004381_abnormal_hair_follicle1.12128591
67MP0003787_abnormal_imprinting1.11118222
68MP0005085_abnormal_gallbladder_physiolo1.10677432
69MP0002148_abnormal_hypersensitivity_rea1.09048196
70MP0005551_abnormal_eye_electrophysiolog1.08980431
71MP0000372_irregular_coat_pigmentation1.08395756
72MP0002139_abnormal_hepatobiliary_system1.04664421
73MP0001346_abnormal_lacrimal_gland1.03696482
74MP0002734_abnormal_mechanical_nocicepti1.02804190
75MP0001986_abnormal_taste_sensitivity1.01973926
76MP0003718_maternal_effect1.00561479
77MP0005670_abnormal_white_adipose0.97829209
78MP0001970_abnormal_pain_threshold0.96388444
79MP0009643_abnormal_urine_homeostasis0.96252776
80MP0005174_abnormal_tail_pigmentation0.94996309
81MP0005253_abnormal_eye_physiology0.94082706
82MP0009785_altered_susceptibility_to0.93834268
83MP0005379_endocrine/exocrine_gland_phen0.93520908
84MP0001486_abnormal_startle_reflex0.93151719
85MP0002138_abnormal_hepatobiliary_system0.92367811
86MP0005084_abnormal_gallbladder_morpholo0.91029517
87MP0002638_abnormal_pupillary_reflex0.89921511
88MP0005220_abnormal_exocrine_pancreas0.89712572
89MP0010386_abnormal_urinary_bladder0.86667569
90MP0003763_abnormal_thymus_physiology0.85714324
91MP0002136_abnormal_kidney_physiology0.85348839
92MP0008004_abnormal_stomach_pH0.84612948
93MP0001502_abnormal_circadian_rhythm0.84035195
94MP0005195_abnormal_posterior_eye0.82729338
95MP0004134_abnormal_chest_morphology0.82711519
96MP0003646_muscle_fatigue0.82563390
97MP0003693_abnormal_embryo_hatching0.78684960
98MP0000049_abnormal_middle_ear0.78261044
99MP0009745_abnormal_behavioral_response0.78149787
100MP0002229_neurodegeneration0.77596369
101MP0005671_abnormal_response_to0.77505909
102MP0001919_abnormal_reproductive_system0.77358157
103MP0002405_respiratory_system_inflammati0.77072874
104MP0005623_abnormal_meninges_morphology0.77033052
105MP0003656_abnormal_erythrocyte_physiolo0.76859266
106MP0002095_abnormal_skin_pigmentation0.76294462
107MP0001944_abnormal_pancreas_morphology0.75932932
108MP0002249_abnormal_larynx_morphology0.75800189
109MP0002928_abnormal_bile_duct0.75771488
110MP0002736_abnormal_nociception_after0.74948835
111MP0001324_abnormal_eye_pigmentation0.70837610
112MP0000026_abnormal_inner_ear0.69328821
113MP0001270_distended_abdomen0.67814258
114MP0001756_abnormal_urination0.67375548
115MP0010329_abnormal_lipoprotein_level0.67115829
116MP0005332_abnormal_amino_acid0.66980861
117MP0003011_delayed_dark_adaptation0.66964696
118MP0009046_muscle_twitch0.66772185
119MP0001186_pigmentation_phenotype0.66613315
120MP0005408_hypopigmentation0.66483177
121MP0001293_anophthalmia0.66085707
122MP0004742_abnormal_vestibular_system0.66078789
123MP0005391_vision/eye_phenotype0.64838939
124MP0000427_abnormal_hair_cycle0.64249590
125MP0002837_dystrophic_cardiac_calcinosis0.64128436
126MP0003077_abnormal_cell_cycle0.64092545
127MP0002938_white_spotting0.64036437
128MP0003890_abnormal_embryonic-extraembry0.63965008
129MP0009764_decreased_sensitivity_to0.63828962
130MP0002557_abnormal_social/conspecific_i0.63457001
131MP0003252_abnormal_bile_duct0.63171048
132MP0005423_abnormal_somatic_nervous0.61885435
133MP0002233_abnormal_nose_morphology0.59903141
134MP0001545_abnormal_hematopoietic_system0.59676295
135MP0005397_hematopoietic_system_phenotyp0.59676295
136MP0005503_abnormal_tendon_morphology0.59398748
137MP0000613_abnormal_salivary_gland0.58181151
138MP0006072_abnormal_retinal_apoptosis0.57965972
139MP0003943_abnormal_hepatobiliary_system0.57196549
140MP0001790_abnormal_immune_system0.56783090
141MP0005387_immune_system_phenotype0.56783090
142MP0002272_abnormal_nervous_system0.55944846
143MP0000631_abnormal_neuroendocrine_gland0.55551311
144MP0001664_abnormal_digestion0.55146373
145MP0002572_abnormal_emotion/affect_behav0.54964316
146MP0002177_abnormal_outer_ear0.54924489
147MP0004133_heterotaxia0.52996612
148MP0005409_darkened_coat_color0.52429701
149MP0001963_abnormal_hearing_physiology0.52127373
150MP0004808_abnormal_hematopoietic_stem0.52096682
151MP0002168_other_aberrant_phenotype0.51844834

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)8.57120363
2Absent/shortened dynein arms (HP:0200106)8.57120363
3Abnormal respiratory motile cilium physiology (HP:0012261)7.54394481
4Abnormal respiratory epithelium morphology (HP:0012253)6.51071379
5Abnormal respiratory motile cilium morphology (HP:0005938)6.51071379
6Abnormal ciliary motility (HP:0012262)6.26923598
7Rhinitis (HP:0012384)6.18948577
8Chronic bronchitis (HP:0004469)5.51629907
9Nephronophthisis (HP:0000090)4.14064167
10Tubulointerstitial nephritis (HP:0001970)3.90808127
11Bronchiectasis (HP:0002110)3.79187483
12Male infertility (HP:0003251)3.67747465
13Abnormality of the renal medulla (HP:0100957)3.55602270
14Infertility (HP:0000789)3.50421394
15Chromosomal breakage induced by crosslinking agents (HP:0003221)3.49355273
16Nasal polyposis (HP:0100582)3.47348353
17True hermaphroditism (HP:0010459)3.36836045
18Pancreatic fibrosis (HP:0100732)3.30915835
19Medial flaring of the eyebrow (HP:0010747)3.30783529
20Bronchitis (HP:0012387)3.13982763
21Molar tooth sign on MRI (HP:0002419)3.11573653
22Abnormality of midbrain morphology (HP:0002418)3.11573653
23Postaxial foot polydactyly (HP:0001830)3.06044604
24Chromsome breakage (HP:0040012)3.06035638
25Congenital hepatic fibrosis (HP:0002612)2.77895685
26Chronic otitis media (HP:0000389)2.74886759
27Median cleft lip (HP:0000161)2.74636428
28Recurrent sinusitis (HP:0011108)2.68355626
29Abnormality of the nasal mucosa (HP:0000433)2.66315555
30Abnormality of the renal cortex (HP:0011035)2.59475333
31Abnormal spermatogenesis (HP:0008669)2.53465276
32Pancreatic cysts (HP:0001737)2.52764979
33Chronic hepatic failure (HP:0100626)2.51103019
34Tubulointerstitial abnormality (HP:0001969)2.49711846
35Nephrogenic diabetes insipidus (HP:0009806)2.47946255
36Facial cleft (HP:0002006)2.47284772
37Congenital primary aphakia (HP:0007707)2.44454963
38Hyperactive renin-angiotensin system (HP:0000841)2.44064213
39Recurrent otitis media (HP:0000403)2.42795472
40Fibular hypoplasia (HP:0003038)2.38731274
41Gait imbalance (HP:0002141)2.33838420
42Cystic liver disease (HP:0006706)2.32659513
43Abnormality of molar (HP:0011077)2.30459590
44Abnormality of molar morphology (HP:0011070)2.30459590
45Azoospermia (HP:0000027)2.29925457
46Anencephaly (HP:0002323)2.29336881
47Aplasia/Hypoplasia of the tongue (HP:0010295)2.28778364
48Aplasia/Hypoplasia of the uvula (HP:0010293)2.26810395
49Abnormality of permanent molar morphology (HP:0011071)2.25727914
50Abnormality of the dental root (HP:0006486)2.25727914
51Taurodontia (HP:0000679)2.25727914
52Tubular atrophy (HP:0000092)2.24348469
53Bile duct proliferation (HP:0001408)2.21005669
54Abnormal biliary tract physiology (HP:0012439)2.21005669
55Atelectasis (HP:0100750)2.20347515
56Ectopic kidney (HP:0000086)2.16597947
57Sclerocornea (HP:0000647)2.15805019
58Meckel diverticulum (HP:0002245)2.14372648
59Abnormality of the dental pulp (HP:0006479)2.12601234
60Decreased circulating renin level (HP:0003351)2.11842111
61Bell-shaped thorax (HP:0001591)2.11240481
62Occipital encephalocele (HP:0002085)2.09715208
63Poor coordination (HP:0002370)2.08986613
64Impulsivity (HP:0100710)2.08537736
65Preaxial hand polydactyly (HP:0001177)2.07884469
66Abnormality of the preputium (HP:0100587)2.07842073
67Postaxial hand polydactyly (HP:0001162)2.06799773
68Renal dysplasia (HP:0000110)2.05708359
69Absent rod-and cone-mediated responses on ERG (HP:0007688)2.04754971
70Abnormality of the ileum (HP:0001549)2.04290648
71Clubbing of toes (HP:0100760)2.03955677
72Asplenia (HP:0001746)2.01382502
73Aplasia/Hypoplasia of the spleen (HP:0010451)2.00813033
74Supernumerary spleens (HP:0009799)2.00169549
75Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.8652686
76Furrowed tongue (HP:0000221)1.99924949
77Male pseudohermaphroditism (HP:0000037)1.98864083
78Abnormal rod and cone electroretinograms (HP:0008323)1.94990700
79Prostate neoplasm (HP:0100787)1.94504639
80Stage 5 chronic kidney disease (HP:0003774)1.93162765
81Retrobulbar optic neuritis (HP:0100654)1.90971287
82Optic neuritis (HP:0100653)1.90971287
83Congenital stationary night blindness (HP:0007642)1.90161043
84Decreased central vision (HP:0007663)1.89976609
85Abnormality of dentin (HP:0010299)1.87570759
86Abnormality of chromosome stability (HP:0003220)1.86308167
87Aplasia/Hypoplasia of the lens (HP:0008063)1.85636306
88Nephropathy (HP:0000112)1.84206810
89Hyperkalemia (HP:0002153)1.83529854
9011 pairs of ribs (HP:0000878)1.79562482
91Short thorax (HP:0010306)1.78740681
92Abnormal drinking behavior (HP:0030082)1.77185304
93Polydipsia (HP:0001959)1.77185304
94Abnormality of the renal collecting system (HP:0004742)1.71998777
95Alveolar cell carcinoma (HP:0006519)1.70993121
96Oculomotor apraxia (HP:0000657)1.70863837
97Bony spicule pigmentary retinopathy (HP:0007737)1.70624555
98Dyschromatopsia (HP:0007641)1.70552520
99Genital tract atresia (HP:0001827)1.70177348
100Nephroblastoma (Wilms tumor) (HP:0002667)1.67420309
101Abnormality of the anterior horn cell (HP:0006802)1.66466891
102Degeneration of anterior horn cells (HP:0002398)1.66466891
103Vaginal atresia (HP:0000148)1.66350668
104Sloping forehead (HP:0000340)1.66267324
105Optic nerve hypoplasia (HP:0000609)1.65444046
106Astigmatism (HP:0000483)1.64406591
107Duplicated collecting system (HP:0000081)1.63244366
108Aganglionic megacolon (HP:0002251)1.62213225
109Aplasia/Hypoplasia of the fibula (HP:0006492)1.61998129
110Renal cortical cysts (HP:0000803)1.58421645
111Renal salt wasting (HP:0000127)1.58282898
112Embryonal renal neoplasm (HP:0011794)1.57905533
113Oligohydramnios (HP:0001562)1.55709765
114Chronic sinusitis (HP:0011109)1.55590342
115Recurrent bronchitis (HP:0002837)1.55551334
116Cone-rod dystrophy (HP:0000548)1.55500067
117Attenuation of retinal blood vessels (HP:0007843)1.54520426
118Abnormality of renin-angiotensin system (HP:0000847)1.48554918
119Abnormality of macular pigmentation (HP:0008002)1.48452386
120Abnormality of chloride homeostasis (HP:0011422)1.41265599
121Polyuria (HP:0000103)1.40561695
122Hyperaldosteronism (HP:0000859)1.34716692
123Retinitis pigmentosa (HP:0000510)1.33620910
124Abolished electroretinogram (ERG) (HP:0000550)1.31040886
125Severe visual impairment (HP:0001141)1.30391973
126Abnormality of renal excretion (HP:0011036)1.28956877
127Hypokalemic alkalosis (HP:0001949)1.23898689
128Abnormality of the hepatic vasculature (HP:0006707)1.20398686
129Absent speech (HP:0001344)1.19601537
130Abnormal urine output (HP:0012590)1.19285263
131Type II lissencephaly (HP:0007260)1.17760144
132Portal hypertension (HP:0001409)1.14955772
133Holoprosencephaly (HP:0001360)1.10827188
134Fetal akinesia sequence (HP:0001989)1.09922170
135Prominent nasal bridge (HP:0000426)1.08610084
136Multicystic kidney dysplasia (HP:0000003)1.08579871
137Tubulointerstitial fibrosis (HP:0005576)1.05554499
138Hyponatremia (HP:0002902)1.05126205
139Absent frontal sinuses (HP:0002688)1.05022934
140Pendular nystagmus (HP:0012043)1.03036375
141Disproportionate short-trunk short stature (HP:0003521)1.01466745

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK35.61614868
2PDK45.61614868
3MST44.48558585
4PDK23.95157733
5ZAK3.09447700
6TESK12.36139901
7TLK12.10486950
8PLK42.07308005
9PRPF4B2.03187783
10MAPK152.00058536
11TXK1.96120717
12NME11.95295115
13STK38L1.91814075
14IRAK11.86693049
15MAPKAPK31.86299572
16MAP4K21.75155725
17MAP3K141.73964212
18BMPR1B1.73216906
19ERBB31.72549259
20PRKD31.68782009
21TAOK21.64704001
22BMPR21.59540608
23ACVR1B1.54449811
24INSRR1.52465430
25SRPK11.50303324
26PINK11.49631125
27GRK11.46684560
28TTK1.45315834
29EIF2AK21.44422122
30IRAK31.44219433
31STK31.43648613
32AKT31.34782853
33CDK31.31244385
34IRAK41.30628619
35CASK1.30346855
36YES11.29472051
37CLK11.26984408
38CCNB11.24238911
39NEK61.23723523
40PNCK1.23077191
41NUAK11.20423480
42MAP3K21.19627579
43PTK2B1.16485640
44NEK21.15327432
45ATR1.14607094
46ICK1.14397930
47BCR1.09002879
48SGK21.08327759
49MAP2K71.05298017
50ADRBK21.02824078
51STK380.95405564
52CHEK20.94657885
53WNK40.92415367
54TEC0.89669667
55PASK0.89442533
56CSK0.88394805
57OXSR10.88249351
58MKNK20.87148971
59VRK10.86029140
60BRD40.82072649
61PRKCI0.80896177
62IRAK20.80856089
63CHUK0.78111363
64STK160.76612281
65ADRBK10.76457727
66MAP3K70.76163316
67PRKCQ0.72186280
68GRK60.72019420
69MAP3K40.69887016
70WNK10.68103792
71ATM0.67617110
72IKBKB0.66897526
73TNIK0.66258861
74CDK190.65679184
75IKBKE0.64124823
76NLK0.63264531
77PLK30.62015612
78SIK30.61350142
79PLK10.60841437
80MAP2K60.60315687
81STK240.57997486
82BRSK20.57971393
83STK40.52790873
84CHEK10.52755354
85LATS10.52518941
86STK390.52323478
87EEF2K0.52111142
88RPS6KB10.51249966
89CDC70.50515079
90CDK120.50204114
91SGK30.49143610
92ERBB20.48365281
93MAP2K20.47764143
94SGK2230.47633532
95SGK4940.47633532
96TAOK30.46645640
97CDK80.46225594
98MAPK130.44501685
99BRAF0.44310211
100STK100.44273732
101TRPM70.44006469
102MAPKAPK50.43369314
103DYRK1B0.42638420
104WEE10.41962613
105MKNK10.41917429
106EPHA20.41325638
107FGFR20.41047951
108MUSK0.40811220
109EIF2AK30.40594269
110BTK0.40557600
111TBK10.40253642
112PRKACA0.39435729
113PRKAA20.39162610
114BLK0.38939481
115DYRK30.38560252
116PDPK10.36115258
117PRKCZ0.35807710
118PIM10.35545822
119FER0.34486379
120RPS6KA50.33646105
121PBK0.33409868
122PRKCA0.32616787
123FRK0.32590166
124PRKCD0.32483927
125WNK30.31517051
126CDK70.31270385
127SGK10.30908938
128PRKCE0.30722618
129CAMKK20.29840989
130TNK20.29705365
131PDK10.29311696
132TIE10.29056336
133PIK3CG0.28689771
134MAP3K30.28091723
135HIPK20.27748884
136EPHA30.27560908
137PRKCG0.27530658
138JAK30.27145333
139CAMKK10.26910167
140ITK0.26511829
141MST1R0.25809665
142NEK90.25455148
143PLK20.25352465
144PRKG10.24983584
145STK110.23572547
146EPHB10.23558100
147ROCK10.22365940
148AURKA0.20780474
149ABL10.20737511
150TGFBR10.20033602
151DYRK20.19495384

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034604.07553894
2Histidine metabolism_Homo sapiens_hsa003403.38921236
3Phenylalanine metabolism_Homo sapiens_hsa003603.15713382
4Basal transcription factors_Homo sapiens_hsa030223.09917222
5Vitamin B6 metabolism_Homo sapiens_hsa007503.09336561
6Tyrosine metabolism_Homo sapiens_hsa003502.58003764
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.53458754
8Caffeine metabolism_Homo sapiens_hsa002322.53225396
9Homologous recombination_Homo sapiens_hsa034402.38865962
10beta-Alanine metabolism_Homo sapiens_hsa004102.35031253
11Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.28371315
12Phototransduction_Homo sapiens_hsa047441.97867178
13Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.96191203
14Graft-versus-host disease_Homo sapiens_hsa053321.87825852
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.76673346
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.72726730
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.70629015
18Autoimmune thyroid disease_Homo sapiens_hsa053201.68907951
19Glutathione metabolism_Homo sapiens_hsa004801.68585129
20Allograft rejection_Homo sapiens_hsa053301.67325285
21NF-kappa B signaling pathway_Homo sapiens_hsa040641.66317039
22Base excision repair_Homo sapiens_hsa034101.62567554
23Butanoate metabolism_Homo sapiens_hsa006501.62455466
24Non-homologous end-joining_Homo sapiens_hsa034501.55673399
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.54951826
26Fatty acid degradation_Homo sapiens_hsa000711.51604971
27Purine metabolism_Homo sapiens_hsa002301.51065307
28Arachidonic acid metabolism_Homo sapiens_hsa005901.46782910
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.39835387
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.38759928
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.38438435
32Peroxisome_Homo sapiens_hsa041461.36292663
33Sphingolipid metabolism_Homo sapiens_hsa006001.36143485
34mRNA surveillance pathway_Homo sapiens_hsa030151.35472164
35Primary bile acid biosynthesis_Homo sapiens_hsa001201.34049979
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.32267888
37Measles_Homo sapiens_hsa051621.31666512
38Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.29370648
39RNA degradation_Homo sapiens_hsa030181.27167817
40Herpes simplex infection_Homo sapiens_hsa051681.26201426
41Cell cycle_Homo sapiens_hsa041101.23716715
42Linoleic acid metabolism_Homo sapiens_hsa005911.19411617
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17361224
44Steroid hormone biosynthesis_Homo sapiens_hsa001401.17167956
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12620748
46Retinol metabolism_Homo sapiens_hsa008301.11984573
47Rheumatoid arthritis_Homo sapiens_hsa053231.10675035
48Pyrimidine metabolism_Homo sapiens_hsa002401.10098970
49Tryptophan metabolism_Homo sapiens_hsa003801.08838884
50Influenza A_Homo sapiens_hsa051641.07607000
51Antigen processing and presentation_Homo sapiens_hsa046121.05822960
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04953762
53Legionellosis_Homo sapiens_hsa051341.04009963
54Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.03502803
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01648081
56Nitrogen metabolism_Homo sapiens_hsa009101.00543845
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97878624
58Olfactory transduction_Homo sapiens_hsa047400.96676242
59Nucleotide excision repair_Homo sapiens_hsa034200.95845534
60Taste transduction_Homo sapiens_hsa047420.95619783
61Dorso-ventral axis formation_Homo sapiens_hsa043200.95318383
62Type I diabetes mellitus_Homo sapiens_hsa049400.94630488
63Salivary secretion_Homo sapiens_hsa049700.92123548
64Hematopoietic cell lineage_Homo sapiens_hsa046400.91248097
65Fatty acid biosynthesis_Homo sapiens_hsa000610.90686096
66Toll-like receptor signaling pathway_Homo sapiens_hsa046200.88174552
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87656147
68RNA polymerase_Homo sapiens_hsa030200.86948340
69Asthma_Homo sapiens_hsa053100.86777742
70Primary immunodeficiency_Homo sapiens_hsa053400.85877491
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.82390381
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81405350
73DNA replication_Homo sapiens_hsa030300.80782438
74Mineral absorption_Homo sapiens_hsa049780.80260366
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79306208
76Hedgehog signaling pathway_Homo sapiens_hsa043400.78847217
77RNA transport_Homo sapiens_hsa030130.77546878
78Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.77369232
79Mismatch repair_Homo sapiens_hsa034300.76670775
80p53 signaling pathway_Homo sapiens_hsa041150.76101826
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75652923
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.74161047
83Malaria_Homo sapiens_hsa051440.73790782
84ABC transporters_Homo sapiens_hsa020100.73080874
85Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.72790566
86TNF signaling pathway_Homo sapiens_hsa046680.72551912
87Oxidative phosphorylation_Homo sapiens_hsa001900.72072557
88Ovarian steroidogenesis_Homo sapiens_hsa049130.71578145
89Glycerolipid metabolism_Homo sapiens_hsa005610.71203554
90Starch and sucrose metabolism_Homo sapiens_hsa005000.70894174
91Ether lipid metabolism_Homo sapiens_hsa005650.70205607
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70072349
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68377518
94Other glycan degradation_Homo sapiens_hsa005110.68215633
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67451005
96Vitamin digestion and absorption_Homo sapiens_hsa049770.66729076
97Tight junction_Homo sapiens_hsa045300.66060160
98Protein export_Homo sapiens_hsa030600.65669887
99Circadian rhythm_Homo sapiens_hsa047100.65167802
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.63317977
101Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62786875
102Metabolic pathways_Homo sapiens_hsa011000.62487326
103Serotonergic synapse_Homo sapiens_hsa047260.61251779
104Epstein-Barr virus infection_Homo sapiens_hsa051690.58653730
105Huntingtons disease_Homo sapiens_hsa050160.58215880
106Nicotine addiction_Homo sapiens_hsa050330.57081265
107Leishmaniasis_Homo sapiens_hsa051400.57068535
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56012616
109Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.54978089
110Inositol phosphate metabolism_Homo sapiens_hsa005620.54417871
111Phagosome_Homo sapiens_hsa041450.52847286
112Chemical carcinogenesis_Homo sapiens_hsa052040.51176645
113Glucagon signaling pathway_Homo sapiens_hsa049220.51097632
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49662710
115Spliceosome_Homo sapiens_hsa030400.49467987
116Toxoplasmosis_Homo sapiens_hsa051450.49229124
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48340467
118Regulation of autophagy_Homo sapiens_hsa041400.48004442
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47648418
120PPAR signaling pathway_Homo sapiens_hsa033200.47012256
121Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.44808604
122Cardiac muscle contraction_Homo sapiens_hsa042600.44634622
123HTLV-I infection_Homo sapiens_hsa051660.42984726
124Morphine addiction_Homo sapiens_hsa050320.42479462
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40455211
126Selenocompound metabolism_Homo sapiens_hsa004500.39540849
127Sulfur relay system_Homo sapiens_hsa041220.39171314
128Wnt signaling pathway_Homo sapiens_hsa043100.38985688
129Propanoate metabolism_Homo sapiens_hsa006400.38538396
130Calcium signaling pathway_Homo sapiens_hsa040200.37662885
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.37516863
132Basal cell carcinoma_Homo sapiens_hsa052170.37062653
133Glycerophospholipid metabolism_Homo sapiens_hsa005640.36775290
134cAMP signaling pathway_Homo sapiens_hsa040240.36418088
135Oocyte meiosis_Homo sapiens_hsa041140.35636914
136Amphetamine addiction_Homo sapiens_hsa050310.34391667
137Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33659081
138Collecting duct acid secretion_Homo sapiens_hsa049660.33480298
139Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.33477483
140Fat digestion and absorption_Homo sapiens_hsa049750.29318019
141Complement and coagulation cascades_Homo sapiens_hsa046100.26165522
142Arginine and proline metabolism_Homo sapiens_hsa003300.24067908
143Alzheimers disease_Homo sapiens_hsa050100.21610699
144Parkinsons disease_Homo sapiens_hsa050120.20481254
145Fatty acid metabolism_Homo sapiens_hsa012120.18872145
146Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18391461
147Sulfur metabolism_Homo sapiens_hsa009200.18210581

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »