

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 8.33306147 |
| 2 | retinal metabolic process (GO:0042574) | 8.18552799 |
| 3 | lung vasculature development (GO:0060426) | 7.78934754 |
| 4 | lung morphogenesis (GO:0060425) | 7.73633591 |
| 5 | platelet dense granule organization (GO:0060155) | 7.22886161 |
| 6 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 7.03572260 |
| 7 | negative regulation of telomere maintenance (GO:0032205) | 6.78099826 |
| 8 | piRNA metabolic process (GO:0034587) | 5.96229114 |
| 9 | negative regulation of execution phase of apoptosis (GO:1900118) | 5.69491302 |
| 10 | histone H3-K36 demethylation (GO:0070544) | 5.59192221 |
| 11 | heparin metabolic process (GO:0030202) | 5.58299615 |
| 12 | heparin biosynthetic process (GO:0030210) | 5.58299615 |
| 13 | regulation of telomere maintenance via telomerase (GO:0032210) | 5.49168130 |
| 14 | positive regulation of mitochondrial fission (GO:0090141) | 5.28718050 |
| 15 | retinoic acid metabolic process (GO:0042573) | 5.02048946 |
| 16 | regulation of histone H3-K27 methylation (GO:0061085) | 4.96798160 |
| 17 | positive regulation of keratinocyte differentiation (GO:0045618) | 4.96253378 |
| 18 | ribosomal small subunit assembly (GO:0000028) | 4.94905637 |
| 19 | endothelial cell morphogenesis (GO:0001886) | 4.92220921 |
| 20 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 4.89748616 |
| 21 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 4.89748616 |
| 22 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 4.69392532 |
| 23 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.44845229 |
| 24 | negative regulation of keratinocyte proliferation (GO:0010839) | 4.35877136 |
| 25 | negative regulation of vascular permeability (GO:0043116) | 4.34899999 |
| 26 | dopamine transport (GO:0015872) | 4.33385204 |
| 27 | regulation of mitochondrial fission (GO:0090140) | 4.23693666 |
| 28 | mannosylation (GO:0097502) | 4.23231900 |
| 29 | regulation of protein polyubiquitination (GO:1902914) | 4.22370769 |
| 30 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.20277575 |
| 31 | thyroid hormone generation (GO:0006590) | 4.12482327 |
| 32 | cellular ketone body metabolic process (GO:0046950) | 4.11187127 |
| 33 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 4.05488832 |
| 34 | protein K6-linked ubiquitination (GO:0085020) | 4.00826350 |
| 35 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.00036711 |
| 36 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.92647224 |
| 37 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 3.92382984 |
| 38 | maturation of SSU-rRNA (GO:0030490) | 3.87077428 |
| 39 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.83038338 |
| 40 | DNA methylation involved in gamete generation (GO:0043046) | 3.83006945 |
| 41 | mitotic cell cycle arrest (GO:0071850) | 3.80987345 |
| 42 | cellular protein catabolic process (GO:0044257) | 3.79346998 |
| 43 | phosphorelay signal transduction system (GO:0000160) | 3.75477168 |
| 44 | regulation of male gonad development (GO:2000018) | 3.72211729 |
| 45 | ribonucleoprotein complex disassembly (GO:0032988) | 3.70245084 |
| 46 | opioid receptor signaling pathway (GO:0038003) | 3.67000377 |
| 47 | regulation of glucokinase activity (GO:0033131) | 3.63995589 |
| 48 | regulation of hexokinase activity (GO:1903299) | 3.63995589 |
| 49 | ketone body metabolic process (GO:1902224) | 3.61024880 |
| 50 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.55941352 |
| 51 | mitochondrial calcium ion transport (GO:0006851) | 3.55045285 |
| 52 | negative regulation of histone methylation (GO:0031061) | 3.51611967 |
| 53 | regulation of telomere maintenance (GO:0032204) | 3.50015822 |
| 54 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.49660200 |
| 55 | regulation of chromatin silencing (GO:0031935) | 3.45274619 |
| 56 | positive regulation of DNA biosynthetic process (GO:2000573) | 3.44694787 |
| 57 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.40456284 |
| 58 | positive regulation of glomerulus development (GO:0090193) | 3.40427553 |
| 59 | thyroid hormone metabolic process (GO:0042403) | 3.39900353 |
| 60 | anterograde synaptic vesicle transport (GO:0048490) | 3.39082197 |
| 61 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.34312371 |
| 62 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.34312371 |
| 63 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.34312371 |
| 64 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 3.30581625 |
| 65 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.29760071 |
| 66 | organic cation transport (GO:0015695) | 3.29390432 |
| 67 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 3.28626324 |
| 68 | auditory receptor cell differentiation (GO:0042491) | 3.26374395 |
| 69 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.24914997 |
| 70 | lipopolysaccharide metabolic process (GO:0008653) | 3.23477931 |
| 71 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 3.21806851 |
| 72 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.19386020 |
| 73 | modulation by symbiont of host immune response (GO:0052553) | 3.19386020 |
| 74 | positive regulation by symbiont of host defense response (GO:0052509) | 3.19386020 |
| 75 | modulation by symbiont of host defense response (GO:0052031) | 3.19386020 |
| 76 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.19386020 |
| 77 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.19386020 |
| 78 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.19291180 |
| 79 | negative regulation of heart growth (GO:0061117) | 3.19102870 |
| 80 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 3.19102870 |
| 81 | phagocytosis, recognition (GO:0006910) | 3.18960160 |
| 82 | negative regulation by host of viral transcription (GO:0043922) | 3.18238763 |
| 83 | secretory granule organization (GO:0033363) | 3.11463823 |
| 84 | L-methionine salvage (GO:0071267) | 3.11352445 |
| 85 | L-methionine biosynthetic process (GO:0071265) | 3.11352445 |
| 86 | amino acid salvage (GO:0043102) | 3.11352445 |
| 87 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.08183859 |
| 88 | ribosomal small subunit biogenesis (GO:0042274) | 3.04577077 |
| 89 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.02982994 |
| 90 | positive regulation of epidermal cell differentiation (GO:0045606) | 3.01414138 |
| 91 | negative regulation of DNA binding (GO:0043392) | 3.00907618 |
| 92 | lateral sprouting from an epithelium (GO:0060601) | 2.95926538 |
| 93 | protein localization to cell surface (GO:0034394) | 2.95433948 |
| 94 | endoderm formation (GO:0001706) | 2.90845080 |
| 95 | viral transcription (GO:0019083) | 2.90217209 |
| 96 | regulation of endothelial cell apoptotic process (GO:2000351) | 2.89685417 |
| 97 | cellular response to interferon-beta (GO:0035458) | 2.88835887 |
| 98 | megakaryocyte development (GO:0035855) | 2.87498959 |
| 99 | negative regulation of sodium ion transport (GO:0010766) | 2.87136652 |
| 100 | drug catabolic process (GO:0042737) | 2.81753481 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 5.13190015 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.08347637 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.93937620 |
| 4 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 3.60860207 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.57740771 |
| 6 | GATA1_22025678_ChIP-Seq_K562_Human | 2.87699689 |
| 7 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.87009642 |
| 8 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.53066399 |
| 9 | FUS_26573619_Chip-Seq_HEK293_Human | 2.40568477 |
| 10 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.36086733 |
| 11 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.33000355 |
| 12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.18795262 |
| 13 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.18337825 |
| 14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 12.9775072 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 1.98317652 |
| 16 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.92273741 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.91902025 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.90525840 |
| 19 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.85236365 |
| 20 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.68026004 |
| 21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.55494715 |
| 22 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.53850870 |
| 23 | AR_20517297_ChIP-Seq_VCAP_Human | 1.50956278 |
| 24 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.50356339 |
| 25 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 1.46967192 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.46926144 |
| 27 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.43048950 |
| 28 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.35022325 |
| 29 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.32963916 |
| 30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.32477569 |
| 31 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.30904478 |
| 32 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.30904478 |
| 33 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.30413110 |
| 34 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.30302332 |
| 35 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.30278540 |
| 36 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.23539666 |
| 37 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.17948470 |
| 38 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.16455815 |
| 39 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.13100818 |
| 40 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.12347461 |
| 41 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.10901399 |
| 42 | P300_19829295_ChIP-Seq_ESCs_Human | 1.10692998 |
| 43 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.08150695 |
| 44 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.07900018 |
| 45 | GATA3_26560356_Chip-Seq_TH2_Human | 1.07564344 |
| 46 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.07158687 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05979736 |
| 48 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.05652268 |
| 49 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05075336 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.05056125 |
| 51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.04071311 |
| 52 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.00153156 |
| 53 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.99665048 |
| 54 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.94999060 |
| 55 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.94076592 |
| 56 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.94018581 |
| 57 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93785622 |
| 58 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93785622 |
| 59 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.91476618 |
| 60 | P300_27268052_Chip-Seq_Bcells_Human | 0.90858441 |
| 61 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.88431156 |
| 62 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.87977902 |
| 63 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.87617568 |
| 64 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.87310584 |
| 65 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.86243712 |
| 66 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.82675200 |
| 67 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.82440104 |
| 68 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.80758539 |
| 69 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.80046843 |
| 70 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.78553493 |
| 71 | AR_25329375_ChIP-Seq_VCAP_Human | 0.78128601 |
| 72 | ERA_21632823_ChIP-Seq_H3396_Human | 0.78021642 |
| 73 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.76830445 |
| 74 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.76741428 |
| 75 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.76422927 |
| 76 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.75604040 |
| 77 | EWS_26573619_Chip-Seq_HEK293_Human | 0.75361926 |
| 78 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.74041262 |
| 79 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.73860858 |
| 80 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.73628669 |
| 81 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73310138 |
| 82 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.73286459 |
| 83 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.71183375 |
| 84 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.71167378 |
| 85 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.70852132 |
| 86 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.70806319 |
| 87 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.69674097 |
| 88 | STAT3_23295773_ChIP-Seq_U87_Human | 0.69610220 |
| 89 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.69489439 |
| 90 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.69019435 |
| 91 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.68846945 |
| 92 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.67534230 |
| 93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.66326212 |
| 94 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.65336559 |
| 95 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.64960619 |
| 96 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.64939962 |
| 97 | RXR_22108803_ChIP-Seq_LS180_Human | 0.64359884 |
| 98 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.63628335 |
| 99 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.62606026 |
| 100 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.61871429 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 4.65288926 |
| 2 | MP0001986_abnormal_taste_sensitivity | 4.30944687 |
| 3 | MP0009379_abnormal_foot_pigmentation | 4.11962924 |
| 4 | MP0003136_yellow_coat_color | 3.61680332 |
| 5 | MP0002277_abnormal_respiratory_mucosa | 3.35007289 |
| 6 | MP0000015_abnormal_ear_pigmentation | 3.24531379 |
| 7 | MP0001764_abnormal_homeostasis | 3.14253478 |
| 8 | MP0002653_abnormal_ependyma_morphology | 3.07784354 |
| 9 | MP0001968_abnormal_touch/_nociception | 2.97090418 |
| 10 | MP0002132_abnormal_respiratory_system | 2.88296208 |
| 11 | MP0005645_abnormal_hypothalamus_physiol | 2.82515269 |
| 12 | MP0002928_abnormal_bile_duct | 2.79618508 |
| 13 | MP0005646_abnormal_pituitary_gland | 2.72253435 |
| 14 | MP0005174_abnormal_tail_pigmentation | 2.58425114 |
| 15 | MP0002736_abnormal_nociception_after | 2.48873082 |
| 16 | MP0002876_abnormal_thyroid_physiology | 2.19947569 |
| 17 | MP0000537_abnormal_urethra_morphology | 2.11794087 |
| 18 | MP0000566_synostosis | 2.11629979 |
| 19 | MP0003942_abnormal_urinary_system | 2.04300610 |
| 20 | MP0002095_abnormal_skin_pigmentation | 2.02790583 |
| 21 | MP0005167_abnormal_blood-brain_barrier | 2.02436835 |
| 22 | MP0001486_abnormal_startle_reflex | 1.91423387 |
| 23 | MP0009053_abnormal_anal_canal | 1.83738869 |
| 24 | MP0003646_muscle_fatigue | 1.79384931 |
| 25 | MP0000678_abnormal_parathyroid_gland | 1.77662651 |
| 26 | MP0003828_pulmonary_edema | 1.73844986 |
| 27 | MP0009278_abnormal_bone_marrow | 1.70804295 |
| 28 | MP0002160_abnormal_reproductive_system | 1.70179517 |
| 29 | MP0005389_reproductive_system_phenotype | 1.69987134 |
| 30 | MP0006292_abnormal_olfactory_placode | 1.61407710 |
| 31 | MP0008872_abnormal_physiological_respon | 1.60753509 |
| 32 | MP0003938_abnormal_ear_development | 1.52902987 |
| 33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.48628011 |
| 34 | MP0002282_abnormal_trachea_morphology | 1.40599336 |
| 35 | MP0000467_abnormal_esophagus_morphology | 1.39414770 |
| 36 | MP0001485_abnormal_pinna_reflex | 1.39303788 |
| 37 | MP0003279_aneurysm | 1.32687152 |
| 38 | MP0003943_abnormal_hepatobiliary_system | 1.30349814 |
| 39 | MP0001293_anophthalmia | 1.29810704 |
| 40 | MP0001853_heart_inflammation | 1.26694272 |
| 41 | MP0000569_abnormal_digit_pigmentation | 1.25194602 |
| 42 | MP0003880_abnormal_central_pattern | 1.20512519 |
| 43 | MP0004130_abnormal_muscle_cell | 1.16243169 |
| 44 | MP0002272_abnormal_nervous_system | 1.09906569 |
| 45 | MP0001919_abnormal_reproductive_system | 1.09842764 |
| 46 | MP0004185_abnormal_adipocyte_glucose | 1.04901146 |
| 47 | MP0005647_abnormal_sex_gland | 1.04676711 |
| 48 | MP0003806_abnormal_nucleotide_metabolis | 1.04543245 |
| 49 | MP0000383_abnormal_hair_follicle | 1.03960352 |
| 50 | MP0001324_abnormal_eye_pigmentation | 1.01276670 |
| 51 | MP0001765_abnormal_ion_homeostasis | 0.98345722 |
| 52 | MP0004145_abnormal_muscle_electrophysio | 0.97249705 |
| 53 | MP0003567_abnormal_fetal_cardiomyocyte | 0.95078176 |
| 54 | MP0009745_abnormal_behavioral_response | 0.94852118 |
| 55 | MP0002098_abnormal_vibrissa_morphology | 0.94604880 |
| 56 | MP0002733_abnormal_thermal_nociception | 0.91570400 |
| 57 | MP0002735_abnormal_chemical_nociception | 0.87676293 |
| 58 | MP0004808_abnormal_hematopoietic_stem | 0.87364326 |
| 59 | MP0001502_abnormal_circadian_rhythm | 0.87176287 |
| 60 | MP0001145_abnormal_male_reproductive | 0.86943511 |
| 61 | MP0003300_gastrointestinal_ulcer | 0.85148943 |
| 62 | MP0005636_abnormal_mineral_homeostasis | 0.84846178 |
| 63 | MP0000653_abnormal_sex_gland | 0.83731407 |
| 64 | MP0008058_abnormal_DNA_repair | 0.83037718 |
| 65 | MP0001905_abnormal_dopamine_level | 0.81995185 |
| 66 | MP0002210_abnormal_sex_determination | 0.81884073 |
| 67 | MP0009333_abnormal_splenocyte_physiolog | 0.81258257 |
| 68 | MP0003195_calcinosis | 0.79366969 |
| 69 | MP0003252_abnormal_bile_duct | 0.79354685 |
| 70 | MP0000631_abnormal_neuroendocrine_gland | 0.78925509 |
| 71 | MP0001175_abnormal_lung_morphology | 0.78863829 |
| 72 | MP0004133_heterotaxia | 0.78256811 |
| 73 | MP0001849_ear_inflammation | 0.72690091 |
| 74 | MP0004264_abnormal_extraembryonic_tissu | 0.72401523 |
| 75 | MP0001545_abnormal_hematopoietic_system | 0.71098914 |
| 76 | MP0005397_hematopoietic_system_phenotyp | 0.71098914 |
| 77 | MP0010329_abnormal_lipoprotein_level | 0.67078699 |
| 78 | MP0000049_abnormal_middle_ear | 0.67027594 |
| 79 | MP0000428_abnormal_craniofacial_morphol | 0.67027459 |
| 80 | MP0005551_abnormal_eye_electrophysiolog | 0.66695779 |
| 81 | MP0002127_abnormal_cardiovascular_syste | 0.65197207 |
| 82 | MP0003632_abnormal_nervous_system | 0.65085442 |
| 83 | MP0003698_abnormal_male_reproductive | 0.64820208 |
| 84 | MP0003638_abnormal_response/metabolism_ | 0.64442383 |
| 85 | MP0003122_maternal_imprinting | 0.63856057 |
| 86 | MP0008775_abnormal_heart_ventricle | 0.63161815 |
| 87 | MP0010368_abnormal_lymphatic_system | 0.62616571 |
| 88 | MP0002249_abnormal_larynx_morphology | 0.62045536 |
| 89 | MP0005195_abnormal_posterior_eye | 0.61934346 |
| 90 | MP0004215_abnormal_myocardial_fiber | 0.60563480 |
| 91 | MP0000534_abnormal_ureter_morphology | 0.57631861 |
| 92 | MP0005464_abnormal_platelet_physiology | 0.57371385 |
| 93 | MP0000026_abnormal_inner_ear | 0.56899113 |
| 94 | MP0003186_abnormal_redox_activity | 0.56869157 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.56859261 |
| 96 | MP0003183_abnormal_peptide_metabolism | 0.55936549 |
| 97 | MP0001756_abnormal_urination | 0.54964590 |
| 98 | MP0004142_abnormal_muscle_tone | 0.53168935 |
| 99 | MP0000013_abnormal_adipose_tissue | 0.52985826 |
| 100 | MP0002572_abnormal_emotion/affect_behav | 0.50921051 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type II lissencephaly (HP:0007260) | 5.00320011 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.58482608 |
| 3 | Supernumerary spleens (HP:0009799) | 4.33019158 |
| 4 | Abnormal biliary tract physiology (HP:0012439) | 3.94785706 |
| 5 | Bile duct proliferation (HP:0001408) | 3.94785706 |
| 6 | Abnormality of the costochondral junction (HP:0000919) | 3.87186165 |
| 7 | Cerebral hypomyelination (HP:0006808) | 3.81040213 |
| 8 | Pancreatic cysts (HP:0001737) | 3.67504406 |
| 9 | Tubulointerstitial nephritis (HP:0001970) | 3.64995937 |
| 10 | Asplenia (HP:0001746) | 3.64962941 |
| 11 | Synostosis involving the elbow (HP:0003938) | 3.63544353 |
| 12 | Humeroradial synostosis (HP:0003041) | 3.63544353 |
| 13 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.58330766 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.53499049 |
| 15 | Tubular atrophy (HP:0000092) | 3.32463823 |
| 16 | Abnormality of the diencephalon (HP:0010662) | 3.31496728 |
| 17 | Atonic seizures (HP:0010819) | 3.11402897 |
| 18 | Pancreatic fibrosis (HP:0100732) | 3.09368246 |
| 19 | Optic nerve hypoplasia (HP:0000609) | 3.01978347 |
| 20 | Renal cortical cysts (HP:0000803) | 2.99593178 |
| 21 | Delayed CNS myelination (HP:0002188) | 2.95789303 |
| 22 | Flat cornea (HP:0007720) | 2.89601862 |
| 23 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.85511004 |
| 24 | Febrile seizures (HP:0002373) | 2.83156332 |
| 25 | Retinal dysplasia (HP:0007973) | 2.81235214 |
| 26 | Enlarged kidneys (HP:0000105) | 2.79872928 |
| 27 | Cerebellar dysplasia (HP:0007033) | 2.78607605 |
| 28 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.77741849 |
| 29 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.75615281 |
| 30 | Fused cervical vertebrae (HP:0002949) | 2.74899504 |
| 31 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.71079271 |
| 32 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.69783251 |
| 33 | Elfin facies (HP:0004428) | 2.69710291 |
| 34 | Absent thumb (HP:0009777) | 2.62799091 |
| 35 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.61608348 |
| 36 | Abnormality of the renal cortex (HP:0011035) | 2.60551449 |
| 37 | Rib fusion (HP:0000902) | 2.58610202 |
| 38 | Alveolar cell carcinoma (HP:0006519) | 2.58085966 |
| 39 | Hypochromic anemia (HP:0001931) | 2.56985566 |
| 40 | Delayed epiphyseal ossification (HP:0002663) | 2.56326973 |
| 41 | Septo-optic dysplasia (HP:0100842) | 2.52952489 |
| 42 | Overriding aorta (HP:0002623) | 2.52113563 |
| 43 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.51975352 |
| 44 | Long nose (HP:0003189) | 2.51952360 |
| 45 | Abnormality of alanine metabolism (HP:0010916) | 2.49011086 |
| 46 | Hyperalaninemia (HP:0003348) | 2.49011086 |
| 47 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.49011086 |
| 48 | Generalized aminoaciduria (HP:0002909) | 2.48354656 |
| 49 | Renovascular hypertension (HP:0100817) | 2.47837181 |
| 50 | Severe muscular hypotonia (HP:0006829) | 2.44508841 |
| 51 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.43939983 |
| 52 | Chorioretinal atrophy (HP:0000533) | 2.41691600 |
| 53 | Cystic liver disease (HP:0006706) | 2.36543206 |
| 54 | Absence seizures (HP:0002121) | 2.34298957 |
| 55 | Symptomatic seizures (HP:0011145) | 2.32298768 |
| 56 | Personality changes (HP:0000751) | 2.30200251 |
| 57 | Hyperacusis (HP:0010780) | 2.30074275 |
| 58 | Status epilepticus (HP:0002133) | 2.24137440 |
| 59 | Reticulocytopenia (HP:0001896) | 2.22755357 |
| 60 | Stenosis of the external auditory canal (HP:0000402) | 2.22301029 |
| 61 | Short 1st metacarpal (HP:0010034) | 2.19617018 |
| 62 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.19617018 |
| 63 | Hypoglycemic coma (HP:0001325) | 2.18701309 |
| 64 | Partial agenesis of the corpus callosum (HP:0001338) | 2.17327216 |
| 65 | Short humerus (HP:0005792) | 2.17125533 |
| 66 | Constricted visual fields (HP:0001133) | 2.17041320 |
| 67 | Maternal diabetes (HP:0009800) | 2.16620457 |
| 68 | Renal duplication (HP:0000075) | 2.16236944 |
| 69 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.15592873 |
| 70 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.12090921 |
| 71 | Anterior segment dysgenesis (HP:0007700) | 2.11278993 |
| 72 | Flat capital femoral epiphysis (HP:0003370) | 2.10336790 |
| 73 | Adrenal hypoplasia (HP:0000835) | 2.08702566 |
| 74 | Pendular nystagmus (HP:0012043) | 2.07748663 |
| 75 | Absent/shortened dynein arms (HP:0200106) | 2.06485559 |
| 76 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.06485559 |
| 77 | Hip dysplasia (HP:0001385) | 2.06168558 |
| 78 | True hermaphroditism (HP:0010459) | 2.05650323 |
| 79 | Fibular aplasia (HP:0002990) | 2.05615678 |
| 80 | Polydipsia (HP:0001959) | 2.05291193 |
| 81 | Abnormal drinking behavior (HP:0030082) | 2.05291193 |
| 82 | Congenital stationary night blindness (HP:0007642) | 2.04940184 |
| 83 | Progressive microcephaly (HP:0000253) | 2.03040884 |
| 84 | Natal tooth (HP:0000695) | 2.02867019 |
| 85 | Carpal bone hypoplasia (HP:0001498) | 2.01168881 |
| 86 | Coarctation of aorta (HP:0001680) | 2.00554270 |
| 87 | Epileptic encephalopathy (HP:0200134) | 2.00519576 |
| 88 | Tubulointerstitial abnormality (HP:0001969) | 2.00210296 |
| 89 | Congenital sensorineural hearing impairment (HP:0008527) | 2.00051834 |
| 90 | Sclerocornea (HP:0000647) | 1.99534067 |
| 91 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.99016440 |
| 92 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.99016440 |
| 93 | Unsteady gait (HP:0002317) | 1.98254763 |
| 94 | Delusions (HP:0000746) | 1.96795894 |
| 95 | Lissencephaly (HP:0001339) | 1.96732861 |
| 96 | Esophageal atresia (HP:0002032) | 1.95308242 |
| 97 | Postnatal microcephaly (HP:0005484) | 1.94540518 |
| 98 | Cortical visual impairment (HP:0100704) | 1.94482734 |
| 99 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.93420829 |
| 100 | Pseudobulbar signs (HP:0002200) | 1.92892691 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 7.57240138 |
| 2 | BRSK2 | 5.84069246 |
| 3 | SRPK1 | 4.95703144 |
| 4 | WEE1 | 4.35514740 |
| 5 | TAOK3 | 3.27525723 |
| 6 | ADRBK2 | 3.16185582 |
| 7 | DYRK2 | 2.84133602 |
| 8 | TIE1 | 2.78792201 |
| 9 | WNK4 | 2.45342193 |
| 10 | STK39 | 2.17691035 |
| 11 | BRSK1 | 2.17118199 |
| 12 | ERN1 | 2.07959565 |
| 13 | GRK1 | 1.96339871 |
| 14 | HIPK2 | 1.77747053 |
| 15 | LRRK2 | 1.57873053 |
| 16 | MOS | 1.44844078 |
| 17 | PAK2 | 1.31339394 |
| 18 | FLT3 | 1.25922005 |
| 19 | ABL2 | 1.18083082 |
| 20 | MAP3K5 | 1.13437530 |
| 21 | CCNB1 | 1.10487760 |
| 22 | GRK7 | 1.09067192 |
| 23 | PLK4 | 1.06446663 |
| 24 | ADRBK1 | 1.03765366 |
| 25 | WNK1 | 0.99727847 |
| 26 | VRK2 | 0.98947338 |
| 27 | GRK5 | 0.98341824 |
| 28 | DAPK2 | 0.93191441 |
| 29 | MATK | 0.92071730 |
| 30 | MAP3K11 | 0.90643981 |
| 31 | ARAF | 0.88211750 |
| 32 | EIF2AK2 | 0.86255293 |
| 33 | MAP3K7 | 0.85950599 |
| 34 | SYK | 0.83090622 |
| 35 | MAP3K9 | 0.82975711 |
| 36 | CSF1R | 0.82413658 |
| 37 | MAP3K13 | 0.82036155 |
| 38 | NTRK1 | 0.79205577 |
| 39 | TEC | 0.79089135 |
| 40 | CASK | 0.77396671 |
| 41 | CSNK1A1 | 0.75265562 |
| 42 | ITK | 0.73349957 |
| 43 | MAPK13 | 0.71819847 |
| 44 | TGFBR2 | 0.70524567 |
| 45 | CAMK1 | 0.64793873 |
| 46 | KIT | 0.63666570 |
| 47 | IGF1R | 0.62659099 |
| 48 | MAP2K2 | 0.61858755 |
| 49 | PIK3CA | 0.59065326 |
| 50 | MAP4K2 | 0.58993229 |
| 51 | PRKAA2 | 0.57280492 |
| 52 | DYRK1B | 0.56331087 |
| 53 | BMPR1B | 0.52903541 |
| 54 | BTK | 0.50528463 |
| 55 | PRKCE | 0.49809980 |
| 56 | VRK1 | 0.49543046 |
| 57 | PRKCQ | 0.48064481 |
| 58 | BCKDK | 0.46030694 |
| 59 | CSNK1E | 0.45344919 |
| 60 | MAP2K4 | 0.45339835 |
| 61 | PRKCG | 0.44279069 |
| 62 | BRAF | 0.43957539 |
| 63 | WNK3 | 0.42184426 |
| 64 | BMX | 0.40622509 |
| 65 | MAPK15 | 0.39161213 |
| 66 | MAP4K1 | 0.38652595 |
| 67 | LIMK1 | 0.36826400 |
| 68 | EPHA4 | 0.33117251 |
| 69 | PDK1 | 0.32002468 |
| 70 | RPS6KA1 | 0.31024382 |
| 71 | IRAK3 | 0.30323445 |
| 72 | LCK | 0.30211164 |
| 73 | PRKCI | 0.28927514 |
| 74 | PDK2 | 0.28509919 |
| 75 | PIM2 | 0.28437782 |
| 76 | EGFR | 0.28119122 |
| 77 | MAP2K7 | 0.26645071 |
| 78 | TGFBR1 | 0.26554319 |
| 79 | STK10 | 0.25922116 |
| 80 | RPS6KB1 | 0.25726444 |
| 81 | MAP3K6 | 0.25502580 |
| 82 | NUAK1 | 0.25354953 |
| 83 | ERBB2 | 0.25271779 |
| 84 | MAP3K4 | 0.24472162 |
| 85 | RPS6KA6 | 0.24062576 |
| 86 | MELK | 0.23911295 |
| 87 | MAPKAPK5 | 0.23416177 |
| 88 | ATR | 0.22022475 |
| 89 | FRK | 0.22015258 |
| 90 | PAK3 | 0.21296520 |
| 91 | PRKG1 | 0.21271873 |
| 92 | TNK2 | 0.21204142 |
| 93 | CSNK2A2 | 0.20901660 |
| 94 | AKT1 | 0.20769634 |
| 95 | MAPK11 | 0.20216769 |
| 96 | NME1 | 0.19973932 |
| 97 | ABL1 | 0.19384463 |
| 98 | PRKCD | 0.19262159 |
| 99 | PRKCZ | 0.18788159 |
| 100 | AURKA | 0.18549882 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sulfur relay system_Homo sapiens_hsa04122 | 3.89169498 |
| 2 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.54284500 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.39484926 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.21001344 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.93498135 |
| 6 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.90491726 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.59911861 |
| 8 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.54284424 |
| 9 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.39162594 |
| 10 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.19897329 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.13973646 |
| 12 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.13356281 |
| 13 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.00497337 |
| 14 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.98639793 |
| 15 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.90263335 |
| 16 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.80945871 |
| 17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.75733792 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.57154348 |
| 19 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.49532189 |
| 20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.48725680 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.48506281 |
| 22 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.45263093 |
| 23 | Parkinsons disease_Homo sapiens_hsa05012 | 1.41241002 |
| 24 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.40557990 |
| 25 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.38001854 |
| 26 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.33544520 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.29404643 |
| 28 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.26784963 |
| 29 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.26502520 |
| 30 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.20677401 |
| 31 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.20637439 |
| 32 | Allograft rejection_Homo sapiens_hsa05330 | 1.17329507 |
| 33 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.13589183 |
| 34 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.12421659 |
| 35 | Protein export_Homo sapiens_hsa03060 | 1.10073829 |
| 36 | Asthma_Homo sapiens_hsa05310 | 1.09182412 |
| 37 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.07614881 |
| 38 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.07438700 |
| 39 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.07234005 |
| 40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.06941288 |
| 41 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.03116796 |
| 42 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.02422256 |
| 43 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.01323629 |
| 44 | Spliceosome_Homo sapiens_hsa03040 | 0.97124702 |
| 45 | Alzheimers disease_Homo sapiens_hsa05010 | 0.93873237 |
| 46 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84042642 |
| 47 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.83794872 |
| 48 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82196428 |
| 49 | Huntingtons disease_Homo sapiens_hsa05016 | 0.80954976 |
| 50 | RNA polymerase_Homo sapiens_hsa03020 | 0.79459739 |
| 51 | Other glycan degradation_Homo sapiens_hsa00511 | 0.76351731 |
| 52 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.75901489 |
| 53 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.75469218 |
| 54 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.73102538 |
| 55 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.71953068 |
| 56 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.71812128 |
| 57 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.71580731 |
| 58 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.71368073 |
| 59 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.70718984 |
| 60 | Insulin secretion_Homo sapiens_hsa04911 | 0.69699813 |
| 61 | Peroxisome_Homo sapiens_hsa04146 | 0.69539515 |
| 62 | Morphine addiction_Homo sapiens_hsa05032 | 0.68661458 |
| 63 | RNA transport_Homo sapiens_hsa03013 | 0.68327603 |
| 64 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.66286662 |
| 65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.65047207 |
| 66 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.62884304 |
| 67 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.58969653 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57734008 |
| 69 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57475784 |
| 70 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.56276089 |
| 71 | RNA degradation_Homo sapiens_hsa03018 | 0.56141464 |
| 72 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.55324767 |
| 73 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.54965937 |
| 74 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.54025025 |
| 75 | Mineral absorption_Homo sapiens_hsa04978 | 0.53884594 |
| 76 | Alcoholism_Homo sapiens_hsa05034 | 0.52605107 |
| 77 | Melanoma_Homo sapiens_hsa05218 | 0.50866900 |
| 78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.50818860 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48260986 |
| 80 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.46874928 |
| 81 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46726384 |
| 82 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44373903 |
| 83 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.44042625 |
| 84 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39591645 |
| 85 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.39493064 |
| 86 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.38570433 |
| 87 | Metabolic pathways_Homo sapiens_hsa01100 | 0.36434561 |
| 88 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.35644665 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.35325217 |
| 90 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.33385702 |
| 91 | Histidine metabolism_Homo sapiens_hsa00340 | 0.30631518 |
| 92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.30545538 |
| 93 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.30442658 |
| 94 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.30416815 |
| 95 | Cocaine addiction_Homo sapiens_hsa05030 | 0.29866734 |
| 96 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.29682684 |
| 97 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.29244648 |
| 98 | ABC transporters_Homo sapiens_hsa02010 | 0.28153795 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.28077799 |
| 100 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.26562078 |

