

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to redox state (GO:0051775) | 6.95985892 |
| 2 | short-term memory (GO:0007614) | 6.06040118 |
| 3 | positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) | 5.92859312 |
| 4 | axoneme assembly (GO:0035082) | 5.85804317 |
| 5 | prenylation (GO:0097354) | 5.78751880 |
| 6 | protein prenylation (GO:0018342) | 5.78751880 |
| 7 | thalamus development (GO:0021794) | 5.34643653 |
| 8 | L-serine metabolic process (GO:0006563) | 5.32592642 |
| 9 | negative regulation of norepinephrine secretion (GO:0010700) | 5.14112292 |
| 10 | sequestering of actin monomers (GO:0042989) | 5.12385908 |
| 11 | organ formation (GO:0048645) | 5.02299941 |
| 12 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 5.01065052 |
| 13 | histone H3-K4 trimethylation (GO:0080182) | 4.84424081 |
| 14 | fibroblast migration (GO:0010761) | 4.75430713 |
| 15 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 4.70394651 |
| 16 | renal system development (GO:0072001) | 4.59423609 |
| 17 | establishment of nucleus localization (GO:0040023) | 4.52926637 |
| 18 | regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 4.43658856 |
| 19 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 4.40865642 |
| 20 | protein heterotetramerization (GO:0051290) | 4.40550447 |
| 21 | protein-cofactor linkage (GO:0018065) | 4.39114461 |
| 22 | limb bud formation (GO:0060174) | 4.31249563 |
| 23 | regulation of microtubule depolymerization (GO:0031114) | 4.25067023 |
| 24 | cerebellar Purkinje cell layer development (GO:0021680) | 4.14610754 |
| 25 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 4.09720805 |
| 26 | regulation of cardioblast proliferation (GO:0003264) | 4.09720805 |
| 27 | neurotransmitter catabolic process (GO:0042135) | 3.96249062 |
| 28 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.93610769 |
| 29 | regulation of DNA-templated transcription, initiation (GO:2000142) | 3.93129953 |
| 30 | hypotonic response (GO:0006971) | 3.90089379 |
| 31 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.85527392 |
| 32 | layer formation in cerebral cortex (GO:0021819) | 3.85429963 |
| 33 | microtubule bundle formation (GO:0001578) | 3.84715610 |
| 34 | positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) | 3.81482115 |
| 35 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.74825173 |
| 36 | negative regulation of microtubule depolymerization (GO:0007026) | 3.74491930 |
| 37 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 3.72599229 |
| 38 | pancreas development (GO:0031016) | 3.68531441 |
| 39 | intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631) | 3.67455425 |
| 40 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 3.61277367 |
| 41 | positive regulation of ERBB signaling pathway (GO:1901186) | 3.55770156 |
| 42 | nonmotile primary cilium assembly (GO:0035058) | 3.55349859 |
| 43 | rRNA catabolic process (GO:0016075) | 3.50232595 |
| 44 | regulation of autophagic vacuole assembly (GO:2000785) | 3.49037915 |
| 45 | adrenergic receptor signaling pathway (GO:0071875) | 3.47642383 |
| 46 | regulation of cell proliferation involved in heart morphogenesis (GO:2000136) | 3.46490774 |
| 47 | hypothalamus development (GO:0021854) | 3.44312827 |
| 48 | lung vasculature development (GO:0060426) | 3.42951133 |
| 49 | peptidyl-lysine trimethylation (GO:0018023) | 3.37975720 |
| 50 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 3.37348807 |
| 51 | mechanosensory behavior (GO:0007638) | 3.37108860 |
| 52 | protein polyglutamylation (GO:0018095) | 3.37082898 |
| 53 | phosphatidylglycerol biosynthetic process (GO:0006655) | 3.34435223 |
| 54 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.33720276 |
| 55 | forebrain morphogenesis (GO:0048853) | 3.25214764 |
| 56 | artery development (GO:0060840) | 3.24687153 |
| 57 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.22467190 |
| 58 | negative regulation of catecholamine secretion (GO:0033604) | 3.20134949 |
| 59 | retinal ganglion cell axon guidance (GO:0031290) | 3.18680742 |
| 60 | regulation of vacuole organization (GO:0044088) | 3.15207822 |
| 61 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.11555474 |
| 62 | spinal cord motor neuron differentiation (GO:0021522) | 3.09982563 |
| 63 | regulation of female receptivity (GO:0045924) | 3.09243118 |
| 64 | heart field specification (GO:0003128) | 3.06971762 |
| 65 | secondary heart field specification (GO:0003139) | 3.06971762 |
| 66 | negative regulation of DNA biosynthetic process (GO:2000279) | 3.04680620 |
| 67 | endocardial cushion morphogenesis (GO:0003203) | 3.00711621 |
| 68 | cardiac right ventricle morphogenesis (GO:0003215) | 3.00387683 |
| 69 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.00266619 |
| 70 | otic vesicle formation (GO:0030916) | 2.99942971 |
| 71 | regulation of uterine smooth muscle contraction (GO:0070472) | 2.98763646 |
| 72 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 2.96415490 |
| 73 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.94985844 |
| 74 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.92351544 |
| 75 | positive regulation of dendritic spine development (GO:0060999) | 2.91087300 |
| 76 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.89135725 |
| 77 | lung-associated mesenchyme development (GO:0060484) | 2.86985244 |
| 78 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.86448271 |
| 79 | piRNA metabolic process (GO:0034587) | 2.86010927 |
| 80 | regulation of microtubule polymerization or depolymerization (GO:0031110) | 2.84834629 |
| 81 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 2.84398131 |
| 82 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 2.84398131 |
| 83 | embryonic foregut morphogenesis (GO:0048617) | 2.83018551 |
| 84 | middle ear morphogenesis (GO:0042474) | 2.81919995 |
| 85 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.81205813 |
| 86 | regulation of action potential (GO:0098900) | 2.80648265 |
| 87 | somite development (GO:0061053) | 2.80305397 |
| 88 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.78408736 |
| 89 | serine family amino acid biosynthetic process (GO:0009070) | 2.77416045 |
| 90 | protoporphyrinogen IX metabolic process (GO:0046501) | 2.77286442 |
| 91 | mitochondrion distribution (GO:0048311) | 2.76720582 |
| 92 | respiratory chain complex IV assembly (GO:0008535) | 2.73942023 |
| 93 | thyroid gland development (GO:0030878) | 2.73460679 |
| 94 | cullin deneddylation (GO:0010388) | 2.69793885 |
| 95 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.69578192 |
| 96 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.69430046 |
| 97 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.68180883 |
| 98 | central nervous system neuron development (GO:0021954) | 2.63509271 |
| 99 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.63045344 |
| 100 | protein neddylation (GO:0045116) | 11.3638329 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.82908934 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.11413716 |
| 3 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.81005125 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.65569014 |
| 5 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.30070427 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.27480807 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.24573545 |
| 8 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.24546319 |
| 9 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.08303642 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.06098798 |
| 11 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 2.02929892 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 11.0715215 |
| 13 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.95568975 |
| 14 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.70974567 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.70273557 |
| 16 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.65908499 |
| 17 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.64817447 |
| 18 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.58312752 |
| 19 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.56200282 |
| 20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.53474258 |
| 21 | P300_19829295_ChIP-Seq_ESCs_Human | 1.52701605 |
| 22 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.52576921 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.48316439 |
| 24 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.45387278 |
| 25 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44155763 |
| 26 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.43558210 |
| 27 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.42151916 |
| 28 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.42151916 |
| 29 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.40763478 |
| 30 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39190060 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39136506 |
| 32 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.35892849 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.34609926 |
| 34 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.33132313 |
| 35 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.32886008 |
| 36 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.30949910 |
| 37 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.25333380 |
| 38 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.24980007 |
| 39 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.23962290 |
| 40 | EWS_26573619_Chip-Seq_HEK293_Human | 1.23477575 |
| 41 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.21203792 |
| 42 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.20119675 |
| 43 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.20058465 |
| 44 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.19311396 |
| 45 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.19309161 |
| 46 | TCF4_23295773_ChIP-Seq_U87_Human | 1.15316150 |
| 47 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.15192663 |
| 48 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.14751153 |
| 49 | TP53_16413492_ChIP-PET_HCT116_Human | 1.14497283 |
| 50 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.13861099 |
| 51 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.13457423 |
| 52 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.12462766 |
| 53 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.10474369 |
| 54 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.09919037 |
| 55 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.07280975 |
| 56 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.05847389 |
| 57 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.05847389 |
| 58 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.05279044 |
| 59 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.03200876 |
| 60 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.02400388 |
| 61 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.01029404 |
| 62 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.00689064 |
| 63 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.00279450 |
| 64 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.99777282 |
| 65 | STAT3_23295773_ChIP-Seq_U87_Human | 0.98992704 |
| 66 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.98439622 |
| 67 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97985164 |
| 68 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.97447958 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.97374436 |
| 70 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.95800237 |
| 71 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.95478647 |
| 72 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.95446491 |
| 73 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.94209834 |
| 74 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.93814261 |
| 75 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.92863723 |
| 76 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.92461104 |
| 77 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.92192702 |
| 78 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.90513842 |
| 79 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.90380610 |
| 80 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.89889241 |
| 81 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.89738531 |
| 82 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.87781740 |
| 83 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87662802 |
| 84 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.87261451 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86993449 |
| 86 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.86574571 |
| 87 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.86266529 |
| 88 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.86050102 |
| 89 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.85492258 |
| 90 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.85330618 |
| 91 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.84757299 |
| 92 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.84687465 |
| 93 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.84306853 |
| 94 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.84263476 |
| 95 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.83242285 |
| 96 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.83149577 |
| 97 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.83026417 |
| 98 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.82309667 |
| 99 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.81858521 |
| 100 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.81267097 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002736_abnormal_nociception_after | 3.74668830 |
| 2 | MP0004147_increased_porphyrin_level | 3.27010966 |
| 3 | MP0002735_abnormal_chemical_nociception | 2.83942898 |
| 4 | MP0009780_abnormal_chondrocyte_physiolo | 2.83870948 |
| 5 | MP0003283_abnormal_digestive_organ | 2.80382922 |
| 6 | MP0001188_hyperpigmentation | 2.69293973 |
| 7 | MP0002876_abnormal_thyroid_physiology | 2.65344990 |
| 8 | MP0002249_abnormal_larynx_morphology | 2.56342074 |
| 9 | MP0003646_muscle_fatigue | 2.52301879 |
| 10 | MP0003122_maternal_imprinting | 2.49912979 |
| 11 | MP0003186_abnormal_redox_activity | 2.43229808 |
| 12 | MP0003123_paternal_imprinting | 2.42288618 |
| 13 | MP0001968_abnormal_touch/_nociception | 2.25940990 |
| 14 | MP0001984_abnormal_olfaction | 2.25302457 |
| 15 | MP0002282_abnormal_trachea_morphology | 2.20521022 |
| 16 | MP0009046_muscle_twitch | 2.17948880 |
| 17 | MP0000631_abnormal_neuroendocrine_gland | 2.15674083 |
| 18 | MP0002751_abnormal_autonomic_nervous | 1.97620851 |
| 19 | MP0000537_abnormal_urethra_morphology | 1.97253738 |
| 20 | MP0003941_abnormal_skin_development | 1.96536444 |
| 21 | MP0005367_renal/urinary_system_phenotyp | 1.95946422 |
| 22 | MP0000516_abnormal_urinary_system | 1.95946422 |
| 23 | MP0000049_abnormal_middle_ear | 1.88298943 |
| 24 | MP0008569_lethality_at_weaning | 1.82498595 |
| 25 | MP0001293_anophthalmia | 1.81612444 |
| 26 | MP0002557_abnormal_social/conspecific_i | 1.79167089 |
| 27 | MP0004142_abnormal_muscle_tone | 1.76066276 |
| 28 | MP0001440_abnormal_grooming_behavior | 1.75273606 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.68310512 |
| 30 | MP0003121_genomic_imprinting | 1.67657689 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.66871797 |
| 32 | MP0004145_abnormal_muscle_electrophysio | 1.59468367 |
| 33 | MP0003937_abnormal_limbs/digits/tail_de | 1.59188722 |
| 34 | MP0008775_abnormal_heart_ventricle | 1.58561474 |
| 35 | MP0003755_abnormal_palate_morphology | 1.58222747 |
| 36 | MP0000681_abnormal_thyroid_gland | 1.58220051 |
| 37 | MP0001919_abnormal_reproductive_system | 1.57361866 |
| 38 | MP0002184_abnormal_innervation | 1.55621352 |
| 39 | MP0003119_abnormal_digestive_system | 1.52238463 |
| 40 | MP0002234_abnormal_pharynx_morphology | 1.51619341 |
| 41 | MP0002132_abnormal_respiratory_system | 1.48447884 |
| 42 | MP0005551_abnormal_eye_electrophysiolog | 1.47305166 |
| 43 | MP0002063_abnormal_learning/memory/cond | 1.45150580 |
| 44 | MP0005365_abnormal_bile_salt | 1.44139593 |
| 45 | MP0004130_abnormal_muscle_cell | 1.43952036 |
| 46 | MP0005257_abnormal_intraocular_pressure | 1.40639181 |
| 47 | MP0002009_preneoplasia | 1.39253656 |
| 48 | MP0002177_abnormal_outer_ear | 1.37124412 |
| 49 | MP0005220_abnormal_exocrine_pancreas | 1.34551138 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.29149767 |
| 51 | MP0004885_abnormal_endolymph | 1.28583571 |
| 52 | MP0008007_abnormal_cellular_replicative | 1.27832871 |
| 53 | MP0000427_abnormal_hair_cycle | 1.27225806 |
| 54 | MP0003638_abnormal_response/metabolism_ | 1.23505171 |
| 55 | MP0000955_abnormal_spinal_cord | 1.22278443 |
| 56 | MP0002089_abnormal_postnatal_growth/wei | 1.17904614 |
| 57 | MP0002160_abnormal_reproductive_system | 1.12053986 |
| 58 | MP0006054_spinal_hemorrhage | 1.10435816 |
| 59 | MP0002572_abnormal_emotion/affect_behav | 1.08844267 |
| 60 | MP0009053_abnormal_anal_canal | 1.07514005 |
| 61 | MP0002067_abnormal_sensory_capabilities | 1.07156576 |
| 62 | MP0002837_dystrophic_cardiac_calcinosis | 1.05582701 |
| 63 | MP0003935_abnormal_craniofacial_develop | 1.05451423 |
| 64 | MP0006276_abnormal_autonomic_nervous | 1.05349535 |
| 65 | MP0002102_abnormal_ear_morphology | 1.04660654 |
| 66 | MP0000230_abnormal_systemic_arterial | 0.99445458 |
| 67 | MP0000377_abnormal_hair_follicle | 0.99251583 |
| 68 | MP0008872_abnormal_physiological_respon | 0.98980596 |
| 69 | MP0000778_abnormal_nervous_system | 0.98652192 |
| 70 | MP0002932_abnormal_joint_morphology | 0.96463596 |
| 71 | MP0004742_abnormal_vestibular_system | 0.96178353 |
| 72 | MP0002090_abnormal_vision | 0.95788755 |
| 73 | MP0003787_abnormal_imprinting | 0.93412932 |
| 74 | MP0002697_abnormal_eye_size | 0.92706064 |
| 75 | MP0002233_abnormal_nose_morphology | 0.90616135 |
| 76 | MP0001486_abnormal_startle_reflex | 0.89832696 |
| 77 | MP0009745_abnormal_behavioral_response | 0.89042650 |
| 78 | MP0002272_abnormal_nervous_system | 0.88414986 |
| 79 | MP0002752_abnormal_somatic_nervous | 0.87797554 |
| 80 | MP0002928_abnormal_bile_duct | 0.87486508 |
| 81 | MP0003938_abnormal_ear_development | 0.87464333 |
| 82 | MP0003656_abnormal_erythrocyte_physiolo | 0.86411835 |
| 83 | MP0001756_abnormal_urination | 0.85622962 |
| 84 | MP0005389_reproductive_system_phenotype | 0.85360763 |
| 85 | MP0003880_abnormal_central_pattern | 0.85266211 |
| 86 | MP0003385_abnormal_body_wall | 0.82266874 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.81617901 |
| 88 | MP0001286_abnormal_eye_development | 0.81559252 |
| 89 | MP0002116_abnormal_craniofacial_bone | 0.77319075 |
| 90 | MP0005391_vision/eye_phenotype | 0.74396450 |
| 91 | MP0002006_tumorigenesis | 0.73691913 |
| 92 | MP0001944_abnormal_pancreas_morphology | 0.72414183 |
| 93 | MP0003633_abnormal_nervous_system | 0.72294130 |
| 94 | MP0001970_abnormal_pain_threshold | 0.71577495 |
| 95 | MP0002064_seizures | 0.70822721 |
| 96 | MP0004811_abnormal_neuron_physiology | 0.69944024 |
| 97 | MP0000358_abnormal_cell_content/ | 0.69117859 |
| 98 | MP0002095_abnormal_skin_pigmentation | 0.68578376 |
| 99 | MP0002069_abnormal_eating/drinking_beha | 0.68108772 |
| 100 | MP0002938_white_spotting | 0.67968288 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Deep palmar crease (HP:0006191) | 7.77476279 |
| 2 | Facial cleft (HP:0002006) | 6.81056136 |
| 3 | Broad-based gait (HP:0002136) | 5.32084489 |
| 4 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.76906515 |
| 5 | Abnormality of the aortic arch (HP:0012303) | 3.75348112 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.63372309 |
| 7 | Bilateral microphthalmos (HP:0007633) | 3.61696494 |
| 8 | Limb hypertonia (HP:0002509) | 3.57918589 |
| 9 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.43102779 |
| 10 | Curly hair (HP:0002212) | 3.37397703 |
| 11 | Capillary hemangiomas (HP:0005306) | 3.30901482 |
| 12 | Hyperglycinemia (HP:0002154) | 3.30326515 |
| 13 | Impulsivity (HP:0100710) | 3.14221270 |
| 14 | Disinhibition (HP:0000734) | 3.09924390 |
| 15 | Wide intermamillary distance (HP:0006610) | 3.06183862 |
| 16 | Cutaneous finger syndactyly (HP:0010554) | 3.01391230 |
| 17 | Cerebral inclusion bodies (HP:0100314) | 3.00500045 |
| 18 | Abnormality of the lower motor neuron (HP:0002366) | 3.00495121 |
| 19 | Abnormality of the labia minora (HP:0012880) | 2.89635580 |
| 20 | Large eyes (HP:0001090) | 2.84012479 |
| 21 | 3-Methylglutaconic aciduria (HP:0003535) | 2.78295498 |
| 22 | Relative macrocephaly (HP:0004482) | 2.76405465 |
| 23 | Attenuation of retinal blood vessels (HP:0007843) | 2.74142496 |
| 24 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.71348705 |
| 25 | Short tibia (HP:0005736) | 2.70893002 |
| 26 | Constricted visual fields (HP:0001133) | 2.67293239 |
| 27 | Hip dysplasia (HP:0001385) | 2.66535345 |
| 28 | Knee flexion contracture (HP:0006380) | 2.65109833 |
| 29 | Hepatic necrosis (HP:0002605) | 2.65000587 |
| 30 | Insidious onset (HP:0003587) | 2.61888794 |
| 31 | Termporal pattern (HP:0011008) | 2.61888794 |
| 32 | Gait imbalance (HP:0002141) | 2.60888800 |
| 33 | Cutaneous syndactyly (HP:0012725) | 2.58653765 |
| 34 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.53884251 |
| 35 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.52796454 |
| 36 | Bifid tongue (HP:0010297) | 2.51140446 |
| 37 | Acute encephalopathy (HP:0006846) | 2.51044501 |
| 38 | Ankle contracture (HP:0006466) | 2.45893958 |
| 39 | Genetic anticipation (HP:0003743) | 2.45718411 |
| 40 | Pancreatic cysts (HP:0001737) | 2.43870080 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.43610606 |
| 42 | Genital tract atresia (HP:0001827) | 2.41515580 |
| 43 | Vaginal atresia (HP:0000148) | 2.38333396 |
| 44 | Insomnia (HP:0100785) | 2.34983369 |
| 45 | Agitation (HP:0000713) | 2.34777691 |
| 46 | Absent eyebrow (HP:0002223) | 2.34563985 |
| 47 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.34312866 |
| 48 | Nephrogenic diabetes insipidus (HP:0009806) | 2.31431967 |
| 49 | Short chin (HP:0000331) | 2.29579492 |
| 50 | Mitochondrial inheritance (HP:0001427) | 2.28779367 |
| 51 | Intention tremor (HP:0002080) | 2.28330657 |
| 52 | Congenital primary aphakia (HP:0007707) | 2.27544030 |
| 53 | Inappropriate behavior (HP:0000719) | 2.27149940 |
| 54 | Anophthalmia (HP:0000528) | 2.18006827 |
| 55 | Megalencephaly (HP:0001355) | 2.16807900 |
| 56 | Absent eyelashes (HP:0000561) | 2.15214456 |
| 57 | Polyphagia (HP:0002591) | 2.12561117 |
| 58 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.11958466 |
| 59 | Aplasia of the phalanges of the hand (HP:0009802) | 2.11958466 |
| 60 | Aplasia involving bones of the extremities (HP:0009825) | 2.11958466 |
| 61 | Pheochromocytoma (HP:0002666) | 2.04555199 |
| 62 | Increased serum lactate (HP:0002151) | 2.03625982 |
| 63 | Increased CSF lactate (HP:0002490) | 1.98566894 |
| 64 | Facial hemangioma (HP:0000329) | 1.97711251 |
| 65 | Tented upper lip vermilion (HP:0010804) | 1.97216131 |
| 66 | Acute lymphatic leukemia (HP:0006721) | 1.97155429 |
| 67 | Disproportionate short-trunk short stature (HP:0003521) | 1.95972868 |
| 68 | Long palpebral fissure (HP:0000637) | 1.95728161 |
| 69 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.94118321 |
| 70 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.94118321 |
| 71 | Intestinal atresia (HP:0011100) | 1.93772181 |
| 72 | Cystic hygroma (HP:0000476) | 1.93511386 |
| 73 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.92843591 |
| 74 | Poor coordination (HP:0002370) | 1.89293635 |
| 75 | Atresia of the external auditory canal (HP:0000413) | 1.89110850 |
| 76 | Neuroendocrine neoplasm (HP:0100634) | 1.86047570 |
| 77 | Abnormality of the thoracic spine (HP:0100711) | 1.85973298 |
| 78 | Myokymia (HP:0002411) | 1.85892041 |
| 79 | Progressive visual loss (HP:0000529) | 1.84684241 |
| 80 | Fibular aplasia (HP:0002990) | 1.81554640 |
| 81 | Hypoplasia of the odontoid process (HP:0003311) | 1.81534561 |
| 82 | High anterior hairline (HP:0009890) | 1.80667231 |
| 83 | Gonadotropin excess (HP:0000837) | 1.80476849 |
| 84 | Renal hypoplasia (HP:0000089) | 1.75213803 |
| 85 | Postaxial foot polydactyly (HP:0001830) | 1.72697853 |
| 86 | Diminished motivation (HP:0000745) | 1.72348608 |
| 87 | Abnormality of the metopic suture (HP:0005556) | 1.71517120 |
| 88 | Postaxial hand polydactyly (HP:0001162) | 1.70530099 |
| 89 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.68746276 |
| 90 | Amyotrophic lateral sclerosis (HP:0007354) | 1.68311450 |
| 91 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.67553861 |
| 92 | Acute necrotizing encephalopathy (HP:0006965) | 1.67348934 |
| 93 | Gaze-evoked nystagmus (HP:0000640) | 1.66830576 |
| 94 | Elfin facies (HP:0004428) | 1.66316221 |
| 95 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.66196038 |
| 96 | Broad distal phalanx of finger (HP:0009836) | 1.65708308 |
| 97 | Restlessness (HP:0000711) | 1.64040952 |
| 98 | Preaxial hand polydactyly (HP:0001177) | 1.63091694 |
| 99 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.62787879 |
| 100 | Scrotal hypoplasia (HP:0000046) | 1.62008362 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MARK1 | 6.27204766 |
| 2 | AKT3 | 5.02456539 |
| 3 | TRIM28 | 4.85035064 |
| 4 | STK39 | 3.06455408 |
| 5 | SIK3 | 2.78102413 |
| 6 | WNK4 | 2.49402557 |
| 7 | OXSR1 | 2.24975659 |
| 8 | MAP3K3 | 2.23470256 |
| 9 | WNK1 | 2.06518137 |
| 10 | CDK19 | 2.05348606 |
| 11 | LIMK1 | 1.94687561 |
| 12 | BMPR1B | 1.92725755 |
| 13 | CASK | 1.84099228 |
| 14 | GRK1 | 1.76439165 |
| 15 | BCR | 1.63429725 |
| 16 | MINK1 | 1.59298067 |
| 17 | WNK3 | 1.53363866 |
| 18 | MST4 | 1.52434421 |
| 19 | MKNK2 | 1.40130067 |
| 20 | SGK2 | 1.34461389 |
| 21 | MAP4K2 | 1.32240373 |
| 22 | RPS6KA4 | 1.15316117 |
| 23 | TSSK6 | 1.15067668 |
| 24 | DYRK1A | 1.12642958 |
| 25 | TAOK3 | 1.11946915 |
| 26 | STK38 | 1.09640262 |
| 27 | FRK | 1.08352655 |
| 28 | SGK3 | 1.05313005 |
| 29 | SGK223 | 1.01936709 |
| 30 | SGK494 | 1.01936709 |
| 31 | BRAF | 1.00923394 |
| 32 | MET | 0.98081363 |
| 33 | TNIK | 0.93978694 |
| 34 | MKNK1 | 0.92729578 |
| 35 | CSNK1D | 0.90469327 |
| 36 | CHEK2 | 0.85067925 |
| 37 | MAP3K4 | 0.83942190 |
| 38 | STK3 | 0.83785313 |
| 39 | RPS6KA5 | 0.82660288 |
| 40 | PIK3CG | 0.80880714 |
| 41 | STK4 | 0.80161828 |
| 42 | BCKDK | 0.76677725 |
| 43 | NTRK2 | 0.76476799 |
| 44 | WEE1 | 0.76228156 |
| 45 | CSNK1A1L | 0.72385601 |
| 46 | MAPK13 | 0.72161420 |
| 47 | CSNK1G1 | 0.70543548 |
| 48 | ROCK1 | 0.70192740 |
| 49 | CSNK2A2 | 0.68698632 |
| 50 | SIK2 | 0.68653765 |
| 51 | ZAK | 0.67373708 |
| 52 | DYRK2 | 0.67162376 |
| 53 | NUAK1 | 0.66659193 |
| 54 | OBSCN | 0.65264187 |
| 55 | CSNK1E | 0.64837516 |
| 56 | PRKCG | 0.62962106 |
| 57 | CDK18 | 0.59651487 |
| 58 | PKN2 | 0.59319068 |
| 59 | DAPK3 | 0.59034714 |
| 60 | SGK1 | 0.57057012 |
| 61 | ATR | 0.56860780 |
| 62 | INSRR | 0.56558944 |
| 63 | EIF2AK3 | 0.56353181 |
| 64 | ABL2 | 0.54309296 |
| 65 | CSNK1A1 | 0.54281461 |
| 66 | KSR1 | 0.53823050 |
| 67 | FGFR2 | 0.52517951 |
| 68 | PHKG2 | 0.51301869 |
| 69 | PHKG1 | 0.51301869 |
| 70 | TEC | 0.50672360 |
| 71 | PRKCQ | 0.49869538 |
| 72 | CDK8 | 0.49668969 |
| 73 | FGFR1 | 0.49167599 |
| 74 | EIF2AK2 | 0.47506040 |
| 75 | CAMK2A | 0.47361277 |
| 76 | CDK14 | 0.46853509 |
| 77 | DYRK3 | 0.46809495 |
| 78 | CSNK1G2 | 0.46473081 |
| 79 | AKT1 | 0.46033765 |
| 80 | ERBB2 | 0.45843714 |
| 81 | GSK3A | 0.45479921 |
| 82 | PRKG1 | 0.43457637 |
| 83 | CDK15 | 0.41428443 |
| 84 | CAMK1G | 0.40933268 |
| 85 | CDC42BPA | 0.39816121 |
| 86 | CSNK2A1 | 0.38959525 |
| 87 | CDK11A | 0.38945982 |
| 88 | RPS6KA3 | 0.38680684 |
| 89 | PRKCE | 0.37567245 |
| 90 | EGFR | 0.35360317 |
| 91 | PLK3 | 0.35000235 |
| 92 | AKT2 | 0.34071239 |
| 93 | CAMK2D | 0.34033220 |
| 94 | CDK5 | 0.32974066 |
| 95 | PAK3 | 0.30676679 |
| 96 | PRKACA | 0.29106679 |
| 97 | PRKDC | 0.28640435 |
| 98 | PRKCI | 0.27734672 |
| 99 | PDGFRB | 0.27600783 |
| 100 | ADRBK2 | 0.26901254 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Caffeine metabolism_Homo sapiens_hsa00232 | 5.14275510 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.84657736 |
| 3 | Basal transcription factors_Homo sapiens_hsa03022 | 3.09934679 |
| 4 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.97698505 |
| 5 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.70884776 |
| 6 | Phototransduction_Homo sapiens_hsa04744 | 2.52264941 |
| 7 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.50703986 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.42360167 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.34312844 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.99651178 |
| 11 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.98373376 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 1.91425654 |
| 13 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.74217230 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.67568141 |
| 15 | Parkinsons disease_Homo sapiens_hsa05012 | 1.67369310 |
| 16 | RNA transport_Homo sapiens_hsa03013 | 1.59664312 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.54050065 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.52543097 |
| 19 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.52283468 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.32618607 |
| 21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.30324647 |
| 22 | Alzheimers disease_Homo sapiens_hsa05010 | 1.25704563 |
| 23 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.19796866 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.18483274 |
| 25 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.11758054 |
| 26 | Olfactory transduction_Homo sapiens_hsa04740 | 1.11639441 |
| 27 | Huntingtons disease_Homo sapiens_hsa05016 | 1.10660397 |
| 28 | Renin secretion_Homo sapiens_hsa04924 | 1.05720022 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.03146681 |
| 30 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.03014710 |
| 31 | Salivary secretion_Homo sapiens_hsa04970 | 1.01130920 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.00951874 |
| 33 | Nicotine addiction_Homo sapiens_hsa05033 | 0.97094271 |
| 34 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.95773459 |
| 35 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.93313866 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91111435 |
| 37 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.85800716 |
| 38 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.85748536 |
| 39 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.84688973 |
| 40 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.83075681 |
| 41 | Circadian entrainment_Homo sapiens_hsa04713 | 0.83070257 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.82440181 |
| 43 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.80178824 |
| 44 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.78677635 |
| 45 | Circadian rhythm_Homo sapiens_hsa04710 | 0.78255714 |
| 46 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.76412190 |
| 47 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.75606630 |
| 48 | Taste transduction_Homo sapiens_hsa04742 | 0.75282796 |
| 49 | DNA replication_Homo sapiens_hsa03030 | 0.74373429 |
| 50 | Proteasome_Homo sapiens_hsa03050 | 0.73543372 |
| 51 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.73348960 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72705578 |
| 53 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.70614534 |
| 54 | GABAergic synapse_Homo sapiens_hsa04727 | 0.70418530 |
| 55 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.69790534 |
| 56 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68999913 |
| 57 | Long-term depression_Homo sapiens_hsa04730 | 0.66433138 |
| 58 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.66165708 |
| 59 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.65366917 |
| 60 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.64159541 |
| 61 | Morphine addiction_Homo sapiens_hsa05032 | 0.63982163 |
| 62 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.63191613 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.62009028 |
| 64 | Platelet activation_Homo sapiens_hsa04611 | 0.61839552 |
| 65 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61044089 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.60625809 |
| 67 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.59594499 |
| 68 | Protein export_Homo sapiens_hsa03060 | 0.58606057 |
| 69 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.57855997 |
| 70 | Glioma_Homo sapiens_hsa05214 | 0.57702152 |
| 71 | Melanoma_Homo sapiens_hsa05218 | 0.56575235 |
| 72 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55317770 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.52824264 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.52678025 |
| 75 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.51419290 |
| 76 | Ribosome_Homo sapiens_hsa03010 | 0.49815040 |
| 77 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.47774026 |
| 78 | Insulin secretion_Homo sapiens_hsa04911 | 0.45871853 |
| 79 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.43912784 |
| 80 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.43659529 |
| 81 | Endometrial cancer_Homo sapiens_hsa05213 | 0.43405707 |
| 82 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.43342322 |
| 83 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.43314619 |
| 84 | RNA degradation_Homo sapiens_hsa03018 | 0.42912437 |
| 85 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.42282692 |
| 86 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.41171267 |
| 87 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.40584026 |
| 88 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.40329344 |
| 89 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.40046309 |
| 90 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39870400 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.39197466 |
| 92 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38231436 |
| 93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38158243 |
| 94 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37273072 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.37101981 |
| 96 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.36711839 |
| 97 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.36106688 |
| 98 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35567546 |
| 99 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.35297354 |
| 100 | Bile secretion_Homo sapiens_hsa04976 | 0.34899398 |

