

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | centriole replication (GO:0007099) | 7.25874852 |
| 2 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 6.61119637 |
| 3 | N-acetylneuraminate metabolic process (GO:0006054) | 6.53867129 |
| 4 | positive regulation of histone deacetylation (GO:0031065) | 5.99327927 |
| 5 | regulation of MHC class II biosynthetic process (GO:0045346) | 5.97718643 |
| 6 | positive regulation of protein deacetylation (GO:0090312) | 5.28312040 |
| 7 | protoporphyrinogen IX metabolic process (GO:0046501) | 5.04190538 |
| 8 | centriole assembly (GO:0098534) | 4.86553446 |
| 9 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 4.79256083 |
| 10 | cellular extravasation (GO:0045123) | 4.78735007 |
| 11 | N-acetylglucosamine metabolic process (GO:0006044) | 4.77383905 |
| 12 | behavioral response to nicotine (GO:0035095) | 4.56794970 |
| 13 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.06638306 |
| 14 | kynurenine metabolic process (GO:0070189) | 4.03448444 |
| 15 | amino sugar catabolic process (GO:0046348) | 3.99967857 |
| 16 | base-excision repair, AP site formation (GO:0006285) | 3.97923016 |
| 17 | indole-containing compound catabolic process (GO:0042436) | 3.97638844 |
| 18 | indolalkylamine catabolic process (GO:0046218) | 3.97638844 |
| 19 | tryptophan catabolic process (GO:0006569) | 3.97638844 |
| 20 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.91119324 |
| 21 | thalamus development (GO:0021794) | 3.90311104 |
| 22 | regulation of chemokine biosynthetic process (GO:0045073) | 3.85929316 |
| 23 | microglial cell activation (GO:0001774) | 3.77979099 |
| 24 | tachykinin receptor signaling pathway (GO:0007217) | 3.73072059 |
| 25 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.70627718 |
| 26 | regulation of growth of symbiont in host (GO:0044126) | 3.70627718 |
| 27 | negative regulation of growth of symbiont in host (GO:0044130) | 3.70627718 |
| 28 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.70627718 |
| 29 | regulation of histone deacetylation (GO:0031063) | 3.62557188 |
| 30 | response to misfolded protein (GO:0051788) | 3.61895540 |
| 31 | regulation of action potential (GO:0098900) | 3.58776538 |
| 32 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.48001979 |
| 33 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.48001979 |
| 34 | reactive oxygen species biosynthetic process (GO:1903409) | 3.46512569 |
| 35 | reciprocal meiotic recombination (GO:0007131) | 3.43148551 |
| 36 | reciprocal DNA recombination (GO:0035825) | 3.43148551 |
| 37 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.42970965 |
| 38 | epithelial cilium movement (GO:0003351) | 3.41672864 |
| 39 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.41488869 |
| 40 | behavioral response to ethanol (GO:0048149) | 3.39552690 |
| 41 | neutrophil mediated immunity (GO:0002446) | 3.22428086 |
| 42 | prostate gland growth (GO:0060736) | 3.21184928 |
| 43 | seminiferous tubule development (GO:0072520) | 3.21047182 |
| 44 | tryptophan metabolic process (GO:0006568) | 3.17576169 |
| 45 | central nervous system neuron axonogenesis (GO:0021955) | 3.16315370 |
| 46 | limb bud formation (GO:0060174) | 3.14514206 |
| 47 | heme biosynthetic process (GO:0006783) | 3.13054673 |
| 48 | regulation of protein deacetylation (GO:0090311) | 3.09401641 |
| 49 | response to folic acid (GO:0051593) | 3.08920724 |
| 50 | somatic diversification of immunoglobulins (GO:0016445) | 3.03881261 |
| 51 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 3.02925549 |
| 52 | cytokinetic process (GO:0032506) | 3.00663275 |
| 53 | aromatic amino acid family catabolic process (GO:0009074) | 3.00581813 |
| 54 | indolalkylamine metabolic process (GO:0006586) | 3.00534838 |
| 55 | glucosamine-containing compound metabolic process (GO:1901071) | 2.98348607 |
| 56 | neural tube formation (GO:0001841) | 2.98193746 |
| 57 | ventricular system development (GO:0021591) | 2.96662483 |
| 58 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 2.95797863 |
| 59 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.94924036 |
| 60 | response to pheromone (GO:0019236) | 2.93330061 |
| 61 | glutamate receptor signaling pathway (GO:0007215) | 2.92588069 |
| 62 | neuronal action potential propagation (GO:0019227) | 2.91024815 |
| 63 | phosphatidylethanolamine metabolic process (GO:0046337) | 2.90138722 |
| 64 | defense response to fungus (GO:0050832) | 2.86098988 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.84190865 |
| 66 | neuronal action potential (GO:0019228) | 2.83680348 |
| 67 | cellular ketone body metabolic process (GO:0046950) | 2.83640967 |
| 68 | cellular response to superoxide (GO:0071451) | 2.82023596 |
| 69 | cellular response to oxygen radical (GO:0071450) | 2.82023596 |
| 70 | removal of superoxide radicals (GO:0019430) | 2.82023596 |
| 71 | negative regulation of multicellular organism growth (GO:0040015) | 2.81147026 |
| 72 | ketone body metabolic process (GO:1902224) | 2.75930181 |
| 73 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.75335780 |
| 74 | detection of light stimulus involved in visual perception (GO:0050908) | 2.75335780 |
| 75 | pyrimidine dimer repair (GO:0006290) | 2.73670514 |
| 76 | regulation of memory T cell differentiation (GO:0043380) | 2.73403659 |
| 77 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.73247098 |
| 78 | isotype switching (GO:0045190) | 2.73247098 |
| 79 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.73247098 |
| 80 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 2.72969272 |
| 81 | negative regulation of mast cell activation (GO:0033004) | 2.69842219 |
| 82 | disruption of cells of other organism (GO:0044364) | 2.69625923 |
| 83 | killing of cells of other organism (GO:0031640) | 2.69625923 |
| 84 | response to oxygen radical (GO:0000305) | 2.69587815 |
| 85 | early endosome to late endosome transport (GO:0045022) | 2.67568063 |
| 86 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.67421821 |
| 87 | protein polyglutamylation (GO:0018095) | 2.66429150 |
| 88 | synaptic transmission, cholinergic (GO:0007271) | 2.64002287 |
| 89 | cellular response to cadmium ion (GO:0071276) | 2.60963019 |
| 90 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.60573103 |
| 91 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 2.59705540 |
| 92 | sex differentiation (GO:0007548) | 2.59621467 |
| 93 | cilium movement (GO:0003341) | 2.59041347 |
| 94 | acrosome reaction (GO:0007340) | 2.56595466 |
| 95 | macrophage chemotaxis (GO:0048246) | 2.56512196 |
| 96 | fucose catabolic process (GO:0019317) | 2.54864648 |
| 97 | L-fucose metabolic process (GO:0042354) | 2.54864648 |
| 98 | L-fucose catabolic process (GO:0042355) | 2.54864648 |
| 99 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.53384913 |
| 100 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.53384913 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 4.29832269 |
| 2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.10994531 |
| 3 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.71121880 |
| 4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.26622992 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 2.97054377 |
| 6 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.70399968 |
| 7 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.68166445 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.64536377 |
| 9 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.61630142 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.51601064 |
| 11 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.39723019 |
| 12 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.35952977 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.31928486 |
| 14 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.09992900 |
| 15 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.04993409 |
| 16 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.92972947 |
| 17 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.89766833 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.88216265 |
| 19 | P300_19829295_ChIP-Seq_ESCs_Human | 1.87969171 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 1.87505754 |
| 21 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.80133094 |
| 22 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.75602744 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.75493628 |
| 24 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.74107942 |
| 25 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.73291421 |
| 26 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.72658145 |
| 27 | TCF4_23295773_ChIP-Seq_U87_Human | 1.66984084 |
| 28 | STAT3_23295773_ChIP-Seq_U87_Human | 1.66754522 |
| 29 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.65160752 |
| 30 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.64328810 |
| 31 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.63086245 |
| 32 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.61492965 |
| 33 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.60009202 |
| 34 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.58325371 |
| 35 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.58323546 |
| 36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.54315757 |
| 37 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.52088595 |
| 38 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.50132177 |
| 39 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.49152332 |
| 40 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.48936009 |
| 41 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.46757553 |
| 42 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.46371294 |
| 43 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.45721325 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44338179 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43092989 |
| 46 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.40842569 |
| 47 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.39896624 |
| 48 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.36791176 |
| 49 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.36791176 |
| 50 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36394734 |
| 51 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.36029785 |
| 52 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35062396 |
| 53 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.32281342 |
| 54 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.30508283 |
| 55 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29625853 |
| 56 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29625853 |
| 57 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.28668705 |
| 58 | AR_25329375_ChIP-Seq_VCAP_Human | 1.28355332 |
| 59 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.26806052 |
| 60 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26806052 |
| 61 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.26686798 |
| 62 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.26500371 |
| 63 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25795917 |
| 64 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.25200880 |
| 65 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.22197248 |
| 66 | RXR_22108803_ChIP-Seq_LS180_Human | 1.21868442 |
| 67 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.20380566 |
| 68 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.19446958 |
| 69 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.19200658 |
| 70 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.16438739 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14657265 |
| 72 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14657265 |
| 73 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14402527 |
| 74 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13902801 |
| 75 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.12958346 |
| 76 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.12241788 |
| 77 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.12113730 |
| 78 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.10814002 |
| 79 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.10226902 |
| 80 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.09689179 |
| 81 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.09465050 |
| 82 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.08768172 |
| 83 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.08701240 |
| 84 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.07841517 |
| 85 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.07072319 |
| 86 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.06262974 |
| 87 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05863640 |
| 88 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.04096059 |
| 89 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03416273 |
| 90 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03081026 |
| 91 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.02894850 |
| 92 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.02260557 |
| 93 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.00843125 |
| 94 | KDM2B_26808549_Chip-Seq_REH_Human | 0.99423063 |
| 95 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.98788200 |
| 96 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.98624639 |
| 97 | TBL1_22424771_ChIP-Seq_293T_Human | 0.98594895 |
| 98 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.97435069 |
| 99 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.95216923 |
| 100 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94459899 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005083_abnormal_biliary_tract | 6.14407109 |
| 2 | MP0003252_abnormal_bile_duct | 4.10485777 |
| 3 | MP0008961_abnormal_basal_metabolism | 3.24940718 |
| 4 | MP0005670_abnormal_white_adipose | 3.19289799 |
| 5 | MP0008058_abnormal_DNA_repair | 2.96916391 |
| 6 | MP0004043_abnormal_pH_regulation | 2.94119914 |
| 7 | MP0001529_abnormal_vocalization | 2.93565658 |
| 8 | MP0000569_abnormal_digit_pigmentation | 2.68926301 |
| 9 | MP0002736_abnormal_nociception_after | 2.64251099 |
| 10 | MP0001968_abnormal_touch/_nociception | 2.61365744 |
| 11 | MP0005085_abnormal_gallbladder_physiolo | 2.53100098 |
| 12 | MP0005365_abnormal_bile_salt | 2.46571982 |
| 13 | MP0003195_calcinosis | 2.24845817 |
| 14 | MP0008872_abnormal_physiological_respon | 2.15821412 |
| 15 | MP0001501_abnormal_sleep_pattern | 2.13521986 |
| 16 | MP0004885_abnormal_endolymph | 2.11795121 |
| 17 | MP0002735_abnormal_chemical_nociception | 2.10313393 |
| 18 | MP0008057_abnormal_DNA_replication | 2.03008313 |
| 19 | MP0010386_abnormal_urinary_bladder | 2.01695512 |
| 20 | MP0005551_abnormal_eye_electrophysiolog | 1.98917481 |
| 21 | MP0002102_abnormal_ear_morphology | 1.95243213 |
| 22 | MP0009745_abnormal_behavioral_response | 1.71575623 |
| 23 | MP0010329_abnormal_lipoprotein_level | 1.67447769 |
| 24 | MP0004924_abnormal_behavior | 1.64729290 |
| 25 | MP0005386_behavior/neurological_phenoty | 1.64729290 |
| 26 | MP0004742_abnormal_vestibular_system | 1.64479326 |
| 27 | MP0008877_abnormal_DNA_methylation | 1.62588304 |
| 28 | MP0003880_abnormal_central_pattern | 1.59650516 |
| 29 | MP0009046_muscle_twitch | 1.53260591 |
| 30 | MP0003787_abnormal_imprinting | 1.51249766 |
| 31 | MP0002837_dystrophic_cardiac_calcinosis | 1.43926978 |
| 32 | MP0001502_abnormal_circadian_rhythm | 1.43134420 |
| 33 | MP0004270_analgesia | 1.42895979 |
| 34 | MP0005367_renal/urinary_system_phenotyp | 1.42884292 |
| 35 | MP0000516_abnormal_urinary_system | 1.42884292 |
| 36 | MP0002638_abnormal_pupillary_reflex | 1.39254478 |
| 37 | MP0002909_abnormal_adrenal_gland | 1.35460131 |
| 38 | MP0002272_abnormal_nervous_system | 1.33063133 |
| 39 | MP0005253_abnormal_eye_physiology | 1.32202019 |
| 40 | MP0001986_abnormal_taste_sensitivity | 1.31932853 |
| 41 | MP0002064_seizures | 1.31155454 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.30785901 |
| 43 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25607762 |
| 44 | MP0002067_abnormal_sensory_capabilities | 1.19715933 |
| 45 | MP0000631_abnormal_neuroendocrine_gland | 1.17499149 |
| 46 | MP0002572_abnormal_emotion/affect_behav | 1.17406346 |
| 47 | MP0003635_abnormal_synaptic_transmissio | 1.17203420 |
| 48 | MP0001486_abnormal_startle_reflex | 1.17120376 |
| 49 | MP0000015_abnormal_ear_pigmentation | 1.15899949 |
| 50 | MP0009115_abnormal_fat_cell | 1.12842926 |
| 51 | MP0002876_abnormal_thyroid_physiology | 1.10917438 |
| 52 | MP0004142_abnormal_muscle_tone | 1.10652050 |
| 53 | MP0000383_abnormal_hair_follicle | 1.10207362 |
| 54 | MP0001970_abnormal_pain_threshold | 1.08982046 |
| 55 | MP0005084_abnormal_gallbladder_morpholo | 1.07342162 |
| 56 | MP0001984_abnormal_olfaction | 1.05176928 |
| 57 | MP0000003_abnormal_adipose_tissue | 1.00909260 |
| 58 | MP0003121_genomic_imprinting | 1.00608731 |
| 59 | MP0005408_hypopigmentation | 1.00437196 |
| 60 | MP0002822_catalepsy | 0.97179673 |
| 61 | MP0002734_abnormal_mechanical_nocicepti | 0.96542472 |
| 62 | MP0006072_abnormal_retinal_apoptosis | 0.95552338 |
| 63 | MP0005646_abnormal_pituitary_gland | 0.90139762 |
| 64 | MP0000427_abnormal_hair_cycle | 0.89754033 |
| 65 | MP0002653_abnormal_ependyma_morphology | 0.86521953 |
| 66 | MP0002063_abnormal_learning/memory/cond | 0.85703883 |
| 67 | MP0002693_abnormal_pancreas_physiology | 0.85568252 |
| 68 | MP0002733_abnormal_thermal_nociception | 0.85518233 |
| 69 | MP0005334_abnormal_fat_pad | 0.84353321 |
| 70 | MP0003718_maternal_effect | 0.83410069 |
| 71 | MP0006292_abnormal_olfactory_placode | 0.79664867 |
| 72 | MP0004019_abnormal_vitamin_homeostasis | 0.77034195 |
| 73 | MP0002229_neurodegeneration | 0.76781645 |
| 74 | MP0000778_abnormal_nervous_system | 0.76264883 |
| 75 | MP0005410_abnormal_fertilization | 0.76210724 |
| 76 | MP0005448_abnormal_energy_balance | 0.74878295 |
| 77 | MP0002118_abnormal_lipid_homeostasis | 0.74351169 |
| 78 | MP0003123_paternal_imprinting | 0.74069822 |
| 79 | MP0002882_abnormal_neuron_morphology | 0.72675866 |
| 80 | MP0003011_delayed_dark_adaptation | 0.72650387 |
| 81 | MP0003878_abnormal_ear_physiology | 0.72221780 |
| 82 | MP0005377_hearing/vestibular/ear_phenot | 0.72221780 |
| 83 | MP0003698_abnormal_male_reproductive | 0.70688050 |
| 84 | MP0006276_abnormal_autonomic_nervous | 0.70026935 |
| 85 | MP0003890_abnormal_embryonic-extraembry | 0.69835933 |
| 86 | MP0000955_abnormal_spinal_cord | 0.69449120 |
| 87 | MP0005174_abnormal_tail_pigmentation | 0.68784628 |
| 88 | MP0002234_abnormal_pharynx_morphology | 0.67665509 |
| 89 | MP0001324_abnormal_eye_pigmentation | 0.67043870 |
| 90 | MP0003633_abnormal_nervous_system | 0.66538234 |
| 91 | MP0001270_distended_abdomen | 0.65767368 |
| 92 | MP0001944_abnormal_pancreas_morphology | 0.65105358 |
| 93 | MP0002078_abnormal_glucose_homeostasis | 0.64800706 |
| 94 | MP0009643_abnormal_urine_homeostasis | 0.64527482 |
| 95 | MP0003646_muscle_fatigue | 0.62832733 |
| 96 | MP0002095_abnormal_skin_pigmentation | 0.61646537 |
| 97 | MP0000230_abnormal_systemic_arterial | 0.61473218 |
| 98 | MP0005266_abnormal_metabolism | 0.61168410 |
| 99 | MP0002752_abnormal_somatic_nervous | 0.61102992 |
| 100 | MP0005195_abnormal_posterior_eye | 0.59932434 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent speech (HP:0001344) | 4.90993627 |
| 2 | Genetic anticipation (HP:0003743) | 4.63052808 |
| 3 | Hyperventilation (HP:0002883) | 4.48158283 |
| 4 | Progressive cerebellar ataxia (HP:0002073) | 4.36963158 |
| 5 | Protruding tongue (HP:0010808) | 4.13520702 |
| 6 | Broad-based gait (HP:0002136) | 3.87151206 |
| 7 | Gaze-evoked nystagmus (HP:0000640) | 3.74691241 |
| 8 | Molar tooth sign on MRI (HP:0002419) | 3.31207222 |
| 9 | Abnormality of midbrain morphology (HP:0002418) | 3.31207222 |
| 10 | Febrile seizures (HP:0002373) | 3.21992587 |
| 11 | Drooling (HP:0002307) | 3.08856549 |
| 12 | Abnormality of the prostate (HP:0008775) | 3.01819471 |
| 13 | Abnormality of the renal cortex (HP:0011035) | 3.01493190 |
| 14 | Pancreatic cysts (HP:0001737) | 2.97671573 |
| 15 | Exotropia (HP:0000577) | 2.94349703 |
| 16 | Widely spaced teeth (HP:0000687) | 2.93638446 |
| 17 | Conical tooth (HP:0000698) | 2.90368090 |
| 18 | Pendular nystagmus (HP:0012043) | 2.87182332 |
| 19 | Prostate neoplasm (HP:0100787) | 2.86408612 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.85973576 |
| 21 | Nephronophthisis (HP:0000090) | 2.85287344 |
| 22 | Excessive salivation (HP:0003781) | 2.83735144 |
| 23 | True hermaphroditism (HP:0010459) | 2.82433133 |
| 24 | Fair hair (HP:0002286) | 2.75184798 |
| 25 | Progressive inability to walk (HP:0002505) | 2.70994904 |
| 26 | Action tremor (HP:0002345) | 2.69275129 |
| 27 | Intestinal atresia (HP:0011100) | 2.67871230 |
| 28 | Medial flaring of the eyebrow (HP:0010747) | 2.67408156 |
| 29 | Atonic seizures (HP:0010819) | 2.61613852 |
| 30 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.48592127 |
| 31 | Generalized hypopigmentation of hair (HP:0011358) | 2.47910654 |
| 32 | Inability to walk (HP:0002540) | 2.47791327 |
| 33 | Pancreatic fibrosis (HP:0100732) | 2.47576847 |
| 34 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.44216214 |
| 35 | Congenital stationary night blindness (HP:0007642) | 2.41238271 |
| 36 | Keratoconus (HP:0000563) | 2.39771019 |
| 37 | Increased corneal curvature (HP:0100692) | 2.39771019 |
| 38 | Congenital sensorineural hearing impairment (HP:0008527) | 2.38290403 |
| 39 | Intellectual disability, progressive (HP:0006887) | 2.36766107 |
| 40 | Clumsiness (HP:0002312) | 2.35479083 |
| 41 | Focal motor seizures (HP:0011153) | 2.35069961 |
| 42 | Epidermoid cyst (HP:0200040) | 2.28873554 |
| 43 | Attenuation of retinal blood vessels (HP:0007843) | 2.26989606 |
| 44 | Hypokalemic alkalosis (HP:0001949) | 2.20207893 |
| 45 | Dialeptic seizures (HP:0011146) | 2.18143668 |
| 46 | Severe visual impairment (HP:0001141) | 2.16781371 |
| 47 | Lissencephaly (HP:0001339) | 2.16776932 |
| 48 | Dysmetric saccades (HP:0000641) | 2.16767931 |
| 49 | Focal seizures (HP:0007359) | 2.16490112 |
| 50 | Absence seizures (HP:0002121) | 2.15927287 |
| 51 | Intellectual disability, severe (HP:0010864) | 2.14755962 |
| 52 | Clubbing of toes (HP:0100760) | 2.13065155 |
| 53 | Tubulointerstitial fibrosis (HP:0005576) | 2.12596067 |
| 54 | Cystic liver disease (HP:0006706) | 2.11771087 |
| 55 | Tubulointerstitial abnormality (HP:0001969) | 2.10928819 |
| 56 | Gait imbalance (HP:0002141) | 2.10633595 |
| 57 | Hypothermia (HP:0002045) | 2.10409540 |
| 58 | Dysdiadochokinesis (HP:0002075) | 2.10039899 |
| 59 | Abnormality of the hepatic vasculature (HP:0006707) | 2.01655783 |
| 60 | Hypoproteinemia (HP:0003075) | 1.99807851 |
| 61 | Abnormality of the ileum (HP:0001549) | 1.98915993 |
| 62 | Neonatal respiratory distress (HP:0002643) | 1.98735717 |
| 63 | Macroglossia (HP:0000158) | 1.96836499 |
| 64 | Blue irides (HP:0000635) | 1.94948732 |
| 65 | Progressive microcephaly (HP:0000253) | 1.94766313 |
| 66 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.94349407 |
| 67 | Meckel diverticulum (HP:0002245) | 1.94003869 |
| 68 | Metabolic alkalosis (HP:0200114) | 1.93606828 |
| 69 | Astigmatism (HP:0000483) | 1.93374305 |
| 70 | Inappropriate behavior (HP:0000719) | 1.92436456 |
| 71 | Tubular atrophy (HP:0000092) | 1.92234640 |
| 72 | Retinitis pigmentosa (HP:0000510) | 1.90532920 |
| 73 | Hypochromic microcytic anemia (HP:0004840) | 1.89576707 |
| 74 | Postaxial foot polydactyly (HP:0001830) | 1.88073191 |
| 75 | Genital tract atresia (HP:0001827) | 1.86858867 |
| 76 | Congenital primary aphakia (HP:0007707) | 1.86699202 |
| 77 | Abnormality of incisor morphology (HP:0011063) | 1.83913787 |
| 78 | Neoplasm of the adrenal cortex (HP:0100641) | 1.83269490 |
| 79 | Abolished electroretinogram (ERG) (HP:0000550) | 1.83188311 |
| 80 | Hypoalbuminemia (HP:0003073) | 1.82287949 |
| 81 | Abnormal albumin level (HP:0012116) | 1.82287949 |
| 82 | Abnormality of the metopic suture (HP:0005556) | 1.81067015 |
| 83 | Abnormality of male internal genitalia (HP:0000022) | 1.80716356 |
| 84 | Abnormality of macular pigmentation (HP:0008002) | 1.79688739 |
| 85 | Volvulus (HP:0002580) | 1.79491499 |
| 86 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.79433978 |
| 87 | Postural instability (HP:0002172) | 1.79243354 |
| 88 | Pachygyria (HP:0001302) | 1.78699391 |
| 89 | Congenital hepatic fibrosis (HP:0002612) | 1.77146597 |
| 90 | Type II lissencephaly (HP:0007260) | 1.77032708 |
| 91 | Vaginal atresia (HP:0000148) | 1.75760001 |
| 92 | Polyuria (HP:0000103) | 1.75493435 |
| 93 | Postaxial hand polydactyly (HP:0001162) | 1.74614842 |
| 94 | Ketoacidosis (HP:0001993) | 1.74171310 |
| 95 | Impaired smooth pursuit (HP:0007772) | 1.73899915 |
| 96 | Abnormality of chloride homeostasis (HP:0011422) | 1.73703086 |
| 97 | Long nose (HP:0003189) | 1.71679796 |
| 98 | Median cleft lip (HP:0000161) | 1.70875593 |
| 99 | Renal cortical cysts (HP:0000803) | 1.70629410 |
| 100 | Oculomotor apraxia (HP:0000657) | 1.70081469 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CCNB1 | 6.66106463 |
| 2 | NEK2 | 4.92467518 |
| 3 | CAMKK2 | 4.72895023 |
| 4 | FRK | 4.21873981 |
| 5 | TAF1 | 3.57364786 |
| 6 | CAMK1D | 3.33663836 |
| 7 | CASK | 2.85499064 |
| 8 | CAMK1G | 2.45267500 |
| 9 | NUAK1 | 2.27176607 |
| 10 | MAPK13 | 2.00836599 |
| 11 | VRK2 | 1.98875487 |
| 12 | MAP3K4 | 1.78121801 |
| 13 | MARK1 | 1.61352344 |
| 14 | STK38L | 1.59094188 |
| 15 | CAMKK1 | 1.57502518 |
| 16 | GRK1 | 1.57367121 |
| 17 | TNIK | 1.51553864 |
| 18 | MAP2K7 | 1.49610570 |
| 19 | WNK4 | 1.48920748 |
| 20 | MAP3K7 | 1.36420920 |
| 21 | CDK19 | 1.32269618 |
| 22 | OXSR1 | 1.29677168 |
| 23 | VRK1 | 1.24038245 |
| 24 | MAP4K2 | 1.14846131 |
| 25 | WNK3 | 1.02421409 |
| 26 | CAMK1 | 1.00987145 |
| 27 | TAOK3 | 0.99100484 |
| 28 | BMPR1B | 0.97677227 |
| 29 | GRK5 | 0.96082000 |
| 30 | MAPKAPK5 | 0.95567372 |
| 31 | PINK1 | 0.94146560 |
| 32 | DYRK2 | 0.91703677 |
| 33 | TXK | 0.91245714 |
| 34 | CSNK1G1 | 0.91076157 |
| 35 | ADRBK2 | 0.88959416 |
| 36 | DYRK1A | 0.88570724 |
| 37 | BRSK2 | 0.88519766 |
| 38 | PIK3CA | 0.86585585 |
| 39 | CSNK1G3 | 0.86400688 |
| 40 | AKT3 | 0.84627654 |
| 41 | PRKCE | 0.84057504 |
| 42 | ACVR1B | 0.82529074 |
| 43 | CSNK1G2 | 0.80161264 |
| 44 | INSRR | 0.79274195 |
| 45 | CHUK | 0.78873515 |
| 46 | SIK2 | 0.70962000 |
| 47 | CSNK1A1L | 0.70560312 |
| 48 | SMG1 | 0.69852583 |
| 49 | PRKAA2 | 0.68565368 |
| 50 | PRKCH | 0.66946951 |
| 51 | SGK2 | 0.65797511 |
| 52 | BCR | 0.64819725 |
| 53 | TNK2 | 0.64635659 |
| 54 | CAMK4 | 0.61725714 |
| 55 | PTK2B | 0.61298882 |
| 56 | PRKCG | 0.60524825 |
| 57 | PDK2 | 0.58786066 |
| 58 | MKNK2 | 0.58203790 |
| 59 | PIK3CG | 0.56342456 |
| 60 | NTRK3 | 0.55098089 |
| 61 | PHKG1 | 0.54272900 |
| 62 | PHKG2 | 0.54272900 |
| 63 | PAK3 | 0.53247946 |
| 64 | DAPK2 | 0.52931053 |
| 65 | ADRBK1 | 0.52903756 |
| 66 | WNK1 | 0.48536512 |
| 67 | MATK | 0.47277435 |
| 68 | DAPK1 | 0.47155037 |
| 69 | ERBB3 | 0.45939114 |
| 70 | PRKG1 | 0.40965535 |
| 71 | TESK2 | 0.40537244 |
| 72 | EIF2AK2 | 0.36946383 |
| 73 | CDK3 | 0.35342584 |
| 74 | SGK1 | 0.35178227 |
| 75 | MAP2K4 | 0.33951030 |
| 76 | TRPM7 | 0.33621916 |
| 77 | PKN1 | 0.33346698 |
| 78 | PLK3 | 0.33219441 |
| 79 | PLK2 | 0.33175941 |
| 80 | HIPK2 | 0.32715862 |
| 81 | CSNK1A1 | 0.32242698 |
| 82 | DYRK3 | 0.30275740 |
| 83 | CSNK1D | 0.29507631 |
| 84 | ERBB2 | 0.29369410 |
| 85 | PRKACA | 0.28579741 |
| 86 | MAP3K6 | 0.27417035 |
| 87 | MAP2K6 | 0.26294687 |
| 88 | PRKCA | 0.25453042 |
| 89 | ERN1 | 0.25344699 |
| 90 | ZAK | 0.23972746 |
| 91 | PLK4 | 0.23748503 |
| 92 | STK3 | 0.23544440 |
| 93 | CAMK2A | 0.23230543 |
| 94 | PRKCZ | 0.22578239 |
| 95 | SYK | 0.21908925 |
| 96 | RPS6KB2 | 0.21030169 |
| 97 | WEE1 | 0.20819717 |
| 98 | STK38 | 0.20502878 |
| 99 | MKNK1 | 0.20492994 |
| 100 | PRKAA1 | 0.20345243 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.03353387 |
| 2 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.72857625 |
| 3 | Phototransduction_Homo sapiens_hsa04744 | 2.50542043 |
| 4 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.48887433 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.43457806 |
| 6 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.42524195 |
| 7 | Nicotine addiction_Homo sapiens_hsa05033 | 2.27788500 |
| 8 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.17008379 |
| 9 | Taste transduction_Homo sapiens_hsa04742 | 2.14431178 |
| 10 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.12838943 |
| 11 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.09730578 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.09461744 |
| 13 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.06295582 |
| 14 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.04415088 |
| 15 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.02059525 |
| 16 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.00547375 |
| 17 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.90768974 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.86716235 |
| 19 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.83195561 |
| 20 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.83116446 |
| 21 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.83058274 |
| 22 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.73364894 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.71780900 |
| 24 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.70703091 |
| 25 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.65437431 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.58476307 |
| 27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.50990459 |
| 28 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.45506467 |
| 29 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.41342459 |
| 30 | Olfactory transduction_Homo sapiens_hsa04740 | 1.39154765 |
| 31 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.39113864 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.38619125 |
| 33 | Histidine metabolism_Homo sapiens_hsa00340 | 1.35670991 |
| 34 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.34131149 |
| 35 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.30760501 |
| 36 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.27128817 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.26033799 |
| 38 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.25483554 |
| 39 | Insulin secretion_Homo sapiens_hsa04911 | 1.22612812 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.19871283 |
| 41 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.18604946 |
| 42 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.10673101 |
| 43 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.10669212 |
| 44 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.10080783 |
| 45 | Cocaine addiction_Homo sapiens_hsa05030 | 1.10045245 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 1.06850542 |
| 47 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.06065647 |
| 48 | ABC transporters_Homo sapiens_hsa02010 | 1.02925360 |
| 49 | Circadian entrainment_Homo sapiens_hsa04713 | 1.00945215 |
| 50 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.97354425 |
| 51 | Morphine addiction_Homo sapiens_hsa05032 | 0.94224631 |
| 52 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.91320201 |
| 53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.91094826 |
| 54 | Circadian rhythm_Homo sapiens_hsa04710 | 0.86272288 |
| 55 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.82200490 |
| 56 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.80253180 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.80200114 |
| 58 | GABAergic synapse_Homo sapiens_hsa04727 | 0.76600714 |
| 59 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.76273097 |
| 60 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.72745976 |
| 61 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.71411642 |
| 62 | Long-term depression_Homo sapiens_hsa04730 | 0.68411048 |
| 63 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.67241465 |
| 64 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.66370365 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65888316 |
| 66 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.64225568 |
| 67 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.64196283 |
| 68 | Axon guidance_Homo sapiens_hsa04360 | 0.63550541 |
| 69 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.62305708 |
| 70 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61861057 |
| 71 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.60686971 |
| 72 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.60162135 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.59882903 |
| 74 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.59647602 |
| 75 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.57461497 |
| 76 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.52353905 |
| 77 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.51231073 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51105981 |
| 79 | Base excision repair_Homo sapiens_hsa03410 | 0.50685693 |
| 80 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.48927374 |
| 81 | Salivary secretion_Homo sapiens_hsa04970 | 0.47710185 |
| 82 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.47686690 |
| 83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.46994901 |
| 84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42742844 |
| 85 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.42104320 |
| 86 | Lysine degradation_Homo sapiens_hsa00310 | 0.41044017 |
| 87 | Renin secretion_Homo sapiens_hsa04924 | 0.39742414 |
| 88 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.39594569 |
| 89 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.37149348 |
| 90 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.37140179 |
| 91 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.36693246 |
| 92 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.32455458 |
| 93 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.29430418 |
| 94 | Protein export_Homo sapiens_hsa03060 | 0.27835227 |
| 95 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.27460231 |
| 96 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.26316855 |
| 97 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.25690370 |
| 98 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.24769448 |
| 99 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.23031770 |
| 100 | RNA degradation_Homo sapiens_hsa03018 | 0.22648655 |

