AGTRAP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.73544342
2negative regulation of cell killing (GO:0031342)4.73544342
3detection of other organism (GO:0098543)4.62598689
4detection of bacterium (GO:0016045)4.54712151
5leukocyte migration involved in inflammatory response (GO:0002523)4.31297479
6antigen processing and presentation of endogenous antigen (GO:0019883)4.31049748
7macrophage activation involved in immune response (GO:0002281)4.28892568
8ribosomal small subunit assembly (GO:0000028)4.22011524
9leukocyte aggregation (GO:0070486)4.15197527
10detection of external biotic stimulus (GO:0098581)3.80771310
11DNA deamination (GO:0045006)3.72065151
12myeloid cell activation involved in immune response (GO:0002275)3.64401796
13cellular extravasation (GO:0045123)3.61927622
14daunorubicin metabolic process (GO:0044597)3.57023620
15polyketide metabolic process (GO:0030638)3.57023620
16doxorubicin metabolic process (GO:0044598)3.57023620
17antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.55169494
18response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.49715723
19response to host immune response (GO:0052572)3.49715723
20response to peptidoglycan (GO:0032494)3.48846318
21negative regulation of phagocytosis (GO:0050765)3.48544920
22regulation of mast cell degranulation (GO:0043304)3.45654256
23detection of molecule of bacterial origin (GO:0032490)3.41598281
24detection of biotic stimulus (GO:0009595)3.38194658
25leukocyte degranulation (GO:0043299)3.36352180
26pyrimidine nucleoside salvage (GO:0043097)3.36045020
27pyrimidine-containing compound salvage (GO:0008655)3.36045020
28regulation of interferon-beta biosynthetic process (GO:0045357)3.33342620
29immunoglobulin mediated immune response (GO:0016064)3.32416061
30neutrophil mediated immunity (GO:0002446)3.30909640
31viral transcription (GO:0019083)3.28484821
32aminoglycoside antibiotic metabolic process (GO:0030647)3.23311003
33regulation of myeloid leukocyte mediated immunity (GO:0002886)3.20927832
34microglial cell activation (GO:0001774)3.18269354
35B cell mediated immunity (GO:0019724)3.16931386
36regulation of B cell receptor signaling pathway (GO:0050855)3.16394792
37positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.16336164
38negative regulation of lymphocyte mediated immunity (GO:0002707)3.16125114
39translational termination (GO:0006415)3.14366227
40response to host (GO:0075136)3.12374281
41response to host defenses (GO:0052200)3.12374281
42response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.12374281
43macrophage activation (GO:0042116)3.12111390
44regulation of mast cell activation involved in immune response (GO:0033006)3.09440367
45positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.08562801
46pentose-phosphate shunt (GO:0006098)3.07864175
47response to interferon-beta (GO:0035456)3.03992546
48ribosomal small subunit biogenesis (GO:0042274)3.03560115
49positive regulation of mast cell activation (GO:0033005)2.99433609
50maturation of SSU-rRNA (GO:0030490)2.98992676
51regulation of leukocyte degranulation (GO:0043300)2.97926238
52telomere maintenance via semi-conservative replication (GO:0032201)2.97600021
53formation of translation preinitiation complex (GO:0001731)2.94285418
54DNA strand elongation involved in DNA replication (GO:0006271)2.92447708
55NADPH regeneration (GO:0006740)2.92364862
56negative regulation of leukocyte mediated immunity (GO:0002704)2.91428141
57IMP biosynthetic process (GO:0006188)2.88424228
58negative regulation of innate immune response (GO:0045824)2.88041208
59regulation of superoxide anion generation (GO:0032928)2.85733214
60response to interferon-alpha (GO:0035455)2.81951297
61production of molecular mediator involved in inflammatory response (GO:0002532)2.81580444
62regulation of mast cell activation (GO:0033003)2.80606918
63regulation of nuclear cell cycle DNA replication (GO:0033262)2.79714795
64nucleoside salvage (GO:0043174)2.79031475
65SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.78532898
66translational elongation (GO:0006414)2.78189942
67positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.77339358
68myeloid leukocyte mediated immunity (GO:0002444)2.77261290
69DNA strand elongation (GO:0022616)2.76964231
70negative regulation of cytokine production involved in immune response (GO:0002719)2.73912340
71regulation of tolerance induction (GO:0002643)2.72739213
72positive regulation of mast cell activation involved in immune response (GO:0033008)2.71534641
73positive regulation of mast cell degranulation (GO:0043306)2.71534641
74neutrophil activation involved in immune response (GO:0002283)2.71078085
75amino sugar catabolic process (GO:0046348)2.70246549
76regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.69198969
77regulation of gamma-delta T cell activation (GO:0046643)2.69070424
78protein targeting to ER (GO:0045047)2.68414378
79cotranslational protein targeting to membrane (GO:0006613)2.67911397
80telomere maintenance via recombination (GO:0000722)2.66549419
81negative regulation of interleukin-6 production (GO:0032715)2.66083920
82purine nucleotide salvage (GO:0032261)2.62831704
83negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.62227196
84regulation of T cell tolerance induction (GO:0002664)2.60465599
85antigen processing and presentation via MHC class Ib (GO:0002475)2.60362134
86translational initiation (GO:0006413)2.60243513
87myeloid leukocyte activation (GO:0002274)2.60109031
88pentose metabolic process (GO:0019321)2.59528136
89regulation of dendritic cell antigen processing and presentation (GO:0002604)2.58941690
90positive regulation of B cell differentiation (GO:0045579)2.58808796
91nucleotide salvage (GO:0043173)2.57891795
92DNA replication initiation (GO:0006270)2.57241350
93interferon-gamma-mediated signaling pathway (GO:0060333)2.56531165
94regulation of chemokine biosynthetic process (GO:0045073)2.56265190
95cellular response to zinc ion (GO:0071294)2.56202964
96purine deoxyribonucleotide catabolic process (GO:0009155)2.55206644
97positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.54473479
98IMP metabolic process (GO:0046040)2.53945359
99DNA replication checkpoint (GO:0000076)2.53321619
100establishment of protein localization to endoplasmic reticulum (GO:0072599)2.51655275
101negative regulation of T cell mediated immunity (GO:0002710)2.51508119
102positive regulation of interleukin-8 secretion (GO:2000484)2.51279482
103nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.51093099
104regulation of B cell differentiation (GO:0045577)2.50828534
105regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.49847293
106regulation of gene silencing by RNA (GO:0060966)2.49391277
107regulation of posttranscriptional gene silencing (GO:0060147)2.49391277
108regulation of gene silencing by miRNA (GO:0060964)2.49391277
109defense response to protozoan (GO:0042832)2.48301680
110pinocytosis (GO:0006907)2.47528249
111response to muramyl dipeptide (GO:0032495)2.47343371
112protein localization to endoplasmic reticulum (GO:0070972)2.47291203
113respiratory burst (GO:0045730)2.46787668
114regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.46572249
115ribosomal large subunit biogenesis (GO:0042273)2.45298701
116superoxide anion generation (GO:0042554)2.44225515
117regulation of RIG-I signaling pathway (GO:0039535)2.43917218
118viral life cycle (GO:0019058)2.42807502
119hydrogen peroxide biosynthetic process (GO:0050665)2.42453032
120positive regulation of interferon-alpha production (GO:0032727)2.42390230
121reactive oxygen species biosynthetic process (GO:1903409)2.41398802
122negative regulation of interleukin-12 production (GO:0032695)2.40641561
123interferon-gamma secretion (GO:0072643)2.40301678
124response to protozoan (GO:0001562)2.37711462
125ribonucleoprotein complex biogenesis (GO:0022613)2.37161616
126positive regulation of gamma-delta T cell activation (GO:0046645)2.35946386
127mitotic recombination (GO:0006312)2.35140394
128positive regulation of chemokine biosynthetic process (GO:0045080)2.34827621
129positive regulation by symbiont of host defense response (GO:0052509)2.33178292
130modulation by symbiont of host defense response (GO:0052031)2.33178292
131modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.33178292
132modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.33178292
133positive regulation by organism of defense response of other organism involved in symbiotic interact2.33178292
134modulation by symbiont of host immune response (GO:0052553)2.33178292
135positive regulation of interferon-beta production (GO:0032728)2.29806102
136regulation of interferon-alpha production (GO:0032647)2.29259774
137response to type I interferon (GO:0034340)2.28986053
138proteasome assembly (GO:0043248)2.28295898
139type I interferon signaling pathway (GO:0060337)2.28204614
140cellular response to type I interferon (GO:0071357)2.28204614
141positive regulation of SMAD protein import into nucleus (GO:0060391)2.27545068
142cytokine production involved in immune response (GO:0002367)2.25878947
1433-UTR-mediated mRNA stabilization (GO:0070935)2.25411763
144neutrophil activation (GO:0042119)2.25024159
145antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.22855147
146NIK/NF-kappaB signaling (GO:0038061)2.22140091
147antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.22060103
148antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.22060103
149granulocyte activation (GO:0036230)2.22027022
150cellular protein complex disassembly (GO:0043624)2.21307252
151cellular response to interferon-beta (GO:0035458)2.21081012
152negative regulation of viral genome replication (GO:0045071)2.20905492
153lipoxygenase pathway (GO:0019372)2.18937844
154telomere maintenance via telomere lengthening (GO:0010833)2.18584161
155Arp2/3 complex-mediated actin nucleation (GO:0034314)2.18341479
156regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.17823895
157ribosome biogenesis (GO:0042254)2.16359607
158negative regulation by host of viral transcription (GO:0043922)2.15792334
159antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.15650374
160negative regulation of nitric oxide biosynthetic process (GO:0045019)2.11875508
161regulation of integrin activation (GO:0033623)2.11157755
162lipopolysaccharide-mediated signaling pathway (GO:0031663)2.10912065
163endosome to melanosome transport (GO:0035646)2.09325862
164endosome to pigment granule transport (GO:0043485)2.09325862
165production of molecular mediator of immune response (GO:0002440)2.08484025
166regulation of type I interferon-mediated signaling pathway (GO:0060338)2.08171061
167leukotriene metabolic process (GO:0006691)2.08008141

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.47061601
2MYC_18555785_ChIP-Seq_MESCs_Mouse2.82935727
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.64996797
4IRF8_22096565_ChIP-ChIP_GC-B_Human2.61887894
5IRF8_21731497_ChIP-ChIP_J774_Mouse2.60256845
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.43906008
7BP1_19119308_ChIP-ChIP_Hs578T_Human2.41392940
8SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.11811963
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.10693320
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.09221027
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.06313203
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.99545557
13IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.98767001
14EST1_17652178_ChIP-ChIP_JURKAT_Human1.93782786
15MYC_19030024_ChIP-ChIP_MESCs_Mouse1.92588525
16KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.92170566
17KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.92170566
18KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.92170566
19NANOG_18555785_ChIP-Seq_MESCs_Mouse1.91143692
20MYC_18358816_ChIP-ChIP_MESCs_Mouse1.91057942
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.89287625
22MYB_21317192_ChIP-Seq_ERMYB_Mouse1.84559169
23FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.82916948
24SPI1_23547873_ChIP-Seq_NB4_Human1.81572372
25* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.80209656
26FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.77056159
27GABP_17652178_ChIP-ChIP_JURKAT_Human1.76305575
28POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.75540614
29* SPI1_23127762_ChIP-Seq_K562_Human1.73399809
30JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.72888395
31* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.69652163
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.68882268
33TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.68221772
34VDR_21846776_ChIP-Seq_THP-1_Human1.59431589
35KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.59125930
36ETS1_20019798_ChIP-Seq_JURKAT_Human1.58224016
37* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.57824409
38RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.57565615
39ELK3_25401928_ChIP-Seq_HUVEC_Human1.56894479
40SCL_19346495_ChIP-Seq_HPC-7_Human1.56579110
41NELFA_20434984_ChIP-Seq_ESCs_Mouse1.56248737
42CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.55815005
43MYC_22102868_ChIP-Seq_BL_Human1.55679828
44* MAF_26560356_Chip-Seq_TH2_Human1.54476342
45NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.52625452
46* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.52109396
47NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.51732537
48SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.50977320
49CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.50871414
50IRF8_27001747_Chip-Seq_BMDM_Mouse1.50543004
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.49490590
52NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.46930232
53SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.46351871
54E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.44036563
55VDR_23849224_ChIP-Seq_CD4+_Human1.43158886
56* LXR_22292898_ChIP-Seq_THP-1_Human1.43091299
57MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.42884502
58SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.42249717
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.42040732
60IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.40943106
61TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40300263
62PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.40230071
63STAT4_19710469_ChIP-ChIP_TH1__Mouse1.39872058
64TCF3_18692474_ChIP-Seq_MEFs_Mouse1.39195567
65XRN2_22483619_ChIP-Seq_HELA_Human1.37345015
66BCL6_27268052_Chip-Seq_Bcells_Human1.34105871
67POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.32375690
68BRD4_27068464_Chip-Seq_AML-cells_Mouse1.32341043
69PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.31951047
70NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.31030674
71CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.29905145
72RUNX1_22412390_ChIP-Seq_EML_Mouse1.29892059
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29088022
74* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.28740397
75MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27072202
76HOXB4_20404135_ChIP-ChIP_EML_Mouse1.26838410
77PU.1_20513432_ChIP-Seq_Bcells_Mouse1.26428353
78CREB1_15753290_ChIP-ChIP_HEK293T_Human1.25657926
79CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.25287324
80* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.25171766
81* BCOR_27268052_Chip-Seq_Bcells_Human1.23042219
82DCP1A_22483619_ChIP-Seq_HELA_Human1.22219212
83* MAF_26560356_Chip-Seq_TH1_Human1.21798262
84* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.21713801
85FOXP3_21729870_ChIP-Seq_TREG_Human1.21701835
86LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.20916616
87TP63_17297297_ChIP-ChIP_HaCaT_Human1.19009677
88YY1_21170310_ChIP-Seq_MESCs_Mouse1.18016467
89MYB_26560356_Chip-Seq_TH2_Human1.17971654
90* TFEB_21752829_ChIP-Seq_HELA_Human1.17098783
91ELK1_19687146_ChIP-ChIP_HELA_Human1.16139476
92* MYB_26560356_Chip-Seq_TH1_Human1.16079555
93HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.14815858
94NOTCH1_21737748_ChIP-Seq_TLL_Human1.14230126
95POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.14139423
96MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.14124138
97* SRF_21415370_ChIP-Seq_HL-1_Mouse1.13939137
98STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.13621602
99* ELF1_20517297_ChIP-Seq_JURKAT_Human1.13327771
100E2F1_21310950_ChIP-Seq_MCF-7_Human1.13178262
101MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13122628
102CIITA_25753668_ChIP-Seq_RAJI_Human1.11168193
103PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11149014
104GABP_19822575_ChIP-Seq_HepG2_Human1.10656272
105CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08825376
106SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07720774
107* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.07667266
108THAP11_20581084_ChIP-Seq_MESCs_Mouse1.07231617
109PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.07018785
110SA1_27219007_Chip-Seq_ERYTHROID_Human1.06747835
111* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06649896
112GATA1_22383799_ChIP-Seq_G1ME_Mouse1.06533464
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.06183813
114* VDR_24763502_ChIP-Seq_THP-1_Human1.04933037
115CTCF_26484167_Chip-Seq_Bcells_Mouse1.04446030
116* NCOR1_26117541_ChIP-Seq_K562_Human1.03417530
117* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.03351089
118* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.03253596
119RACK7_27058665_Chip-Seq_MCF-7_Human1.02995656
120GATA2_22383799_ChIP-Seq_G1ME_Mouse1.02040016
121THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.01685523
122GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00373944
123* UTX_26944678_Chip-Seq_JUKART_Human1.00269871
124LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.00075953
125RARG_19884340_ChIP-ChIP_MEFs_Mouse1.00073253
126CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99628651
127STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.99119593
128CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.98619420
129SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97901661
130KLF4_18555785_ChIP-Seq_MESCs_Mouse0.96563684
131TTF2_22483619_ChIP-Seq_HELA_Human0.95936956
132* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.95791234
133TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.95408768
134* TCF7_22412390_ChIP-Seq_EML_Mouse0.95269118
135* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.95003197

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis3.20802569
2MP0001835_abnormal_antigen_presentation2.84292469
3MP0008260_abnormal_autophagy2.80924557
4MP0009785_altered_susceptibility_to2.50077601
5MP0003191_abnormal_cellular_cholesterol2.46523183
6MP0003693_abnormal_embryo_hatching2.44653080
7MP0009278_abnormal_bone_marrow2.37523200
8MP0003436_decreased_susceptibility_to2.35414357
9MP0010352_gastrointestinal_tract_polyps2.33898707
10MP0002148_abnormal_hypersensitivity_rea2.08266347
11MP0005174_abnormal_tail_pigmentation2.00204060
12MP0004957_abnormal_blastocyst_morpholog1.98114516
13MP0005025_abnormal_response_to1.96468280
14MP0000490_abnormal_crypts_of1.91556071
15MP0002396_abnormal_hematopoietic_system1.90920104
16MP0003724_increased_susceptibility_to1.90841278
17MP0005058_abnormal_lysosome_morphology1.88346411
18MP0000685_abnormal_immune_system1.86453120
19MP0002419_abnormal_innate_immunity1.85890890
20MP0003111_abnormal_nucleus_morphology1.85341413
21MP0001545_abnormal_hematopoietic_system1.84095507
22MP0005397_hematopoietic_system_phenotyp1.84095507
23MP0005000_abnormal_immune_tolerance1.83319467
24MP0005671_abnormal_response_to1.82892415
25MP0003077_abnormal_cell_cycle1.77310849
26MP0002452_abnormal_antigen_presenting1.75958578
27MP0003075_altered_response_to1.71760688
28MP0009333_abnormal_splenocyte_physiolog1.70479098
29MP0003300_gastrointestinal_ulcer1.68270692
30MP0001800_abnormal_humoral_immune1.66510955
31MP0010094_abnormal_chromosome_stability1.66151532
32MP0008057_abnormal_DNA_replication1.64012494
33MP0000343_altered_response_to1.61412591
34MP0005387_immune_system_phenotype1.61393179
35MP0001790_abnormal_immune_system1.61393179
36MP0004808_abnormal_hematopoietic_stem1.59584148
37MP0001819_abnormal_immune_cell1.59280913
38MP0002420_abnormal_adaptive_immunity1.58371345
39MP0002723_abnormal_immune_serum1.57203802
40MP0002877_abnormal_melanocyte_morpholog1.56868150
41MP0005451_abnormal_body_composition1.53787300
42MP0010155_abnormal_intestine_physiology1.53549880
43MP0003566_abnormal_cell_adhesion1.52933518
44MP0003186_abnormal_redox_activity1.48687322
45MP0006082_CNS_inflammation1.46548986
46MP0008007_abnormal_cellular_replicative1.46224554
47MP0002405_respiratory_system_inflammati1.46180588
48MP0002398_abnormal_bone_marrow1.45282558
49MP0008058_abnormal_DNA_repair1.45111993
50MP0001853_heart_inflammation1.43116021
51MP0002722_abnormal_immune_system1.36725730
52MP0000858_altered_metastatic_potential1.36296186
53MP0003448_altered_tumor_morphology1.35388736
54MP0000689_abnormal_spleen_morphology1.34898834
55MP0002254_reproductive_system_inflammat1.34792808
56MP0000716_abnormal_immune_system1.33991541
57MP0005083_abnormal_biliary_tract1.32165737
58MP0003763_abnormal_thymus_physiology1.31649820
59MP0005464_abnormal_platelet_physiology1.30995288
60MP0003828_pulmonary_edema1.28244302
61MP0001845_abnormal_inflammatory_respons1.26652237
62MP0002429_abnormal_blood_cell1.26037910
63MP0002006_tumorigenesis1.24181147
64MP0004947_skin_inflammation1.18079176
65MP0001533_abnormal_skeleton_physiology1.17475625
66MP0003567_abnormal_fetal_cardiomyocyte1.16644243
67MP0001873_stomach_inflammation1.16574261
68MP0005166_decreased_susceptibility_to1.16106174
69MP0003303_peritoneal_inflammation1.12917386
70MP0004883_abnormal_blood_vessel1.12383175
71MP0003172_abnormal_lysosome_physiology1.12304394
72MP0004381_abnormal_hair_follicle1.11196135
73MP0002998_abnormal_bone_remodeling1.10051643
74MP0010307_abnormal_tumor_latency1.09131811
75MP0002019_abnormal_tumor_incidence1.08625887
76MP0008004_abnormal_stomach_pH1.07276710
77MP0001851_eye_inflammation1.07223488
78MP0005164_abnormal_response_to1.06757869
79MP0000703_abnormal_thymus_morphology1.06426496
80MP0003786_premature_aging1.05848608
81MP0002166_altered_tumor_susceptibility1.05243463
82MP0009840_abnormal_foam_cell1.05073975
83MP0005023_abnormal_wound_healing1.04797148
84MP0005075_abnormal_melanosome_morpholog1.04568115
85MP0009763_increased_sensitivity_to1.03311000
86MP0000465_gastrointestinal_hemorrhage1.01527855
87MP0000371_diluted_coat_color1.00468670
88MP0008469_abnormal_protein_level1.00085137
89MP0000313_abnormal_cell_death0.99335074
90MP0000015_abnormal_ear_pigmentation0.95677444
91MP0001849_ear_inflammation0.95625656
92MP0005319_abnormal_enzyme/_coenzyme0.95235964
93MP0006036_abnormal_mitochondrial_physio0.94311535
94MP0004264_abnormal_extraembryonic_tissu0.94117676
95MP0002277_abnormal_respiratory_mucosa0.92951088
96MP0006035_abnormal_mitochondrial_morpho0.91254137
97MP0000350_abnormal_cell_proliferation0.90805528
98MP0006054_spinal_hemorrhage0.90498563
99MP0005310_abnormal_salivary_gland0.89753411
100MP0008932_abnormal_embryonic_tissue0.89238751
101MP0002095_abnormal_skin_pigmentation0.86738509
102MP0004510_myositis0.85653648
103MP0003941_abnormal_skin_development0.84247773
104MP0003183_abnormal_peptide_metabolism0.81227473
105MP0002086_abnormal_extraembryonic_tissu0.81223490
106MP0001958_emphysema0.81180927
107MP0003453_abnormal_keratinocyte_physiol0.80517038
108MP0009765_abnormal_xenobiotic_induced0.79902677
109MP0002136_abnormal_kidney_physiology0.77953756
110MP0003795_abnormal_bone_structure0.77303987
111MP0004133_heterotaxia0.76566441
112MP0009764_decreased_sensitivity_to0.76428532
113MP0004782_abnormal_surfactant_physiolog0.76250852
114MP0008873_increased_physiological_sensi0.74271158
115MP0003646_muscle_fatigue0.74184939
116MP0002132_abnormal_respiratory_system0.73991640
117MP0003279_aneurysm0.73914864
118MP0005380_embryogenesis_phenotype0.73356299
119MP0001672_abnormal_embryogenesis/_devel0.73356299
120MP0001542_abnormal_bone_strength0.73272407
121MP0002933_joint_inflammation0.72271042
122MP0005390_skeleton_phenotype0.72063858
123MP0004858_abnormal_nervous_system0.71496020
124MP0003984_embryonic_growth_retardation0.71481296
125MP0003136_yellow_coat_color0.71452892
126MP0006292_abnormal_olfactory_placode0.71353265
127MP0005076_abnormal_cell_differentiation0.70688756
128MP0003866_abnormal_defecation0.70312870
129MP0002653_abnormal_ependyma_morphology0.69823196
130MP0001663_abnormal_digestive_system0.69315174
131MP0002088_abnormal_embryonic_growth/wei0.69159660
132MP0003656_abnormal_erythrocyte_physiolo0.68978008
133MP0000604_amyloidosis0.63249904
134MP0000358_abnormal_cell_content/0.60096957
135MP0005165_increased_susceptibility_to0.58045467
136MP0003011_delayed_dark_adaptation0.56446659

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.81703750
2Eczematoid dermatitis (HP:0000976)4.41286032
3Recurrent bacterial skin infections (HP:0005406)4.01033648
4Abnormality of macrophages (HP:0004311)3.91455387
5Reticulocytopenia (HP:0001896)3.58516551
6Myositis (HP:0100614)3.46696531
7Hepatosplenomegaly (HP:0001433)3.27368786
8Vacuolated lymphocytes (HP:0001922)3.18669203
9Elevated erythrocyte sedimentation rate (HP:0003565)3.17308372
10Episodic fever (HP:0001954)3.05263183
11Purpura (HP:0000979)2.97921435
12Gastrointestinal infarctions (HP:0005244)2.97575079
13Increased serum ferritin (HP:0003281)2.97070829
14Encephalitis (HP:0002383)2.93606665
15Amyloidosis (HP:0011034)2.92750449
16Loss of speech (HP:0002371)2.91923313
17Mediastinal lymphadenopathy (HP:0100721)2.87191480
18Increased IgE level (HP:0003212)2.82115423
19Hypochromic microcytic anemia (HP:0004840)2.80901006
20Orchitis (HP:0100796)2.77753227
21Abnormality of cells of the erythroid lineage (HP:0012130)2.74149903
22Recurrent fungal infections (HP:0002841)2.72712800
23Abnormal number of erythroid precursors (HP:0012131)2.71150366
24Thrombocytosis (HP:0001894)2.70470107
25Keratoconjunctivitis sicca (HP:0001097)2.67685635
26Chronic mucocutaneous candidiasis (HP:0002728)2.65163323
27Recurrent cutaneous fungal infections (HP:0011370)2.65163323
28Recurrent gram-negative bacterial infections (HP:0005420)2.63926044
29Pustule (HP:0200039)2.63700710
30Agnosia (HP:0010524)2.63623424
31Chromsome breakage (HP:0040012)2.62648610
32Aplastic anemia (HP:0001915)2.60121668
33Autoimmune thrombocytopenia (HP:0001973)2.60023236
34Chromosomal breakage induced by crosslinking agents (HP:0003221)2.57090256
35Petechiae (HP:0000967)2.56516503
36IgM deficiency (HP:0002850)2.56388584
37Abnormality of iron homeostasis (HP:0011031)2.54467413
38Epistaxis (HP:0000421)2.52662585
39Recurrent viral infections (HP:0004429)2.50322867
40Chest pain (HP:0100749)2.43251117
41Gingivitis (HP:0000230)2.42405918
42Keratoconjunctivitis (HP:0001096)2.41316851
43Nausea (HP:0002018)2.41272689
44Interstitial pulmonary disease (HP:0006530)2.38695052
45Systemic lupus erythematosus (HP:0002725)2.38412254
46Chronic obstructive pulmonary disease (HP:0006510)2.37749725
47Obstructive lung disease (HP:0006536)2.37749725
48Abnormality of T cell physiology (HP:0011840)2.35611055
49Gingival bleeding (HP:0000225)2.34341694
50Poikiloderma (HP:0001029)2.29420623
51Progressive neurologic deterioration (HP:0002344)2.28176038
52Hypertensive crisis (HP:0100735)2.27650755
53Type I transferrin isoform profile (HP:0003642)2.26759530
54Hypochromic anemia (HP:0001931)2.26641304
55Abnormality of the heme biosynthetic pathway (HP:0010472)2.25253196
56Amaurosis fugax (HP:0100576)2.21998251
57Optic neuritis (HP:0100653)2.20713423
58Retrobulbar optic neuritis (HP:0100654)2.20713423
59Granulocytopenia (HP:0001913)2.20597880
60Hypergammaglobulinemia (HP:0010702)2.19351062
61Poor head control (HP:0002421)2.19090362
62Hemoptysis (HP:0002105)2.15631877
63Increased IgM level (HP:0003496)2.15597205
64Pallor (HP:0000980)2.14942267
65Gastrointestinal inflammation (HP:0004386)2.14785394
66Spontaneous hematomas (HP:0007420)2.14685650
67Selective tooth agenesis (HP:0001592)2.14014943
68Abnormality of the nasal mucosa (HP:0000433)2.13553274
69Inflammation of the large intestine (HP:0002037)2.11259871
70Pulmonary infiltrates (HP:0002113)2.10926723
71Eosinophilia (HP:0001880)2.09380375
72Recurrent skin infections (HP:0001581)2.08596921
73Leukocytosis (HP:0001974)2.08231678
74Carpal bone hypoplasia (HP:0001498)2.07798015
7511 pairs of ribs (HP:0000878)2.06593384
76Premature loss of primary teeth (HP:0006323)2.03855791
77Acute hepatic failure (HP:0006554)2.02187584
78Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.00991860
79Abnormal delayed hypersensitivity skin test (HP:0002963)2.00955075
80Microcytic anemia (HP:0001935)2.00427227
81Urticaria (HP:0001025)1.99256858
82Abnormality of T cells (HP:0002843)1.98962212
83Abnormality of transition element cation homeostasis (HP:0011030)1.98760546
84Distal lower limb muscle weakness (HP:0009053)1.98040693
85Myelodysplasia (HP:0002863)1.97035965
86Multiple enchondromatosis (HP:0005701)1.97015274
87Arterial thrombosis (HP:0004420)1.96265982
88Abnormal gallbladder physiology (HP:0012438)1.95686328
89Cholecystitis (HP:0001082)1.95686328
90Cellulitis (HP:0100658)1.95596303
91Aplasia/Hypoplasia of the sacrum (HP:0008517)1.95455141
92Lymphopenia (HP:0001888)1.93734349
93Basal ganglia calcification (HP:0002135)1.91799385
94Abnormal platelet volume (HP:0011876)1.91703807
95Rough bone trabeculation (HP:0100670)1.91472312
96Bone marrow hypocellularity (HP:0005528)1.91205980
97Spinal muscular atrophy (HP:0007269)1.90993039
98Osteomyelitis (HP:0002754)1.90890020
99Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.87116828
100Meningitis (HP:0001287)1.85855280
101Albinism (HP:0001022)1.84963136
102Panhypogammaglobulinemia (HP:0003139)1.84537887
103Disinhibition (HP:0000734)1.83771265
104Absent thumb (HP:0009777)1.83172840
105Vasculitis (HP:0002633)1.83127131
106Lymphoma (HP:0002665)1.83041585
107Metaphyseal cupping (HP:0003021)1.81955849
108Abnormality of chromosome stability (HP:0003220)1.81401103
109Nasal polyposis (HP:0100582)1.80881022
110Abnormality of eosinophils (HP:0001879)1.80270292
111Sepsis (HP:0100806)1.79451306
112Gangrene (HP:0100758)1.79384593
113Splenomegaly (HP:0001744)1.79337949
114Severe visual impairment (HP:0001141)1.77901730
115Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.77806332
116Decreased activity of mitochondrial respiratory chain (HP:0008972)1.77806332
117Pulmonary embolism (HP:0002204)1.77197090
118Anorexia (HP:0002039)1.76454622
119Ragged-red muscle fibers (HP:0003200)1.75901173
120Respiratory difficulties (HP:0002880)1.75785004
121Periodontitis (HP:0000704)1.75460294
122Skin rash (HP:0000988)1.75396019
123Abnormality of the anterior horn cell (HP:0006802)1.74788784
124Degeneration of anterior horn cells (HP:0002398)1.74788784
125Aplasia/hypoplasia of the humerus (HP:0006507)1.74264909
126Cervical subluxation (HP:0003308)1.72912583
127Prostate neoplasm (HP:0100787)1.72395176
128Abnormality of liposaccharide metabolism (HP:0010968)1.71437112
129Abnormality of glycosphingolipid metabolism (HP:0004343)1.71437112
130Abnormality of glycolipid metabolism (HP:0010969)1.71437112
131Proximal tubulopathy (HP:0000114)1.70546719
132Basal cell carcinoma (HP:0002671)1.69955389
133Stomatitis (HP:0010280)1.68940710
134Generalized aminoaciduria (HP:0002909)1.67772392
135Colon cancer (HP:0003003)1.66831042
136Increased cerebral lipofuscin (HP:0011813)1.66154434
137Meckel diverticulum (HP:0002245)1.65551309
138Mucopolysacchariduria (HP:0008155)1.64426310
139Urinary glycosaminoglycan excretion (HP:0003541)1.64426310
140Chronic otitis media (HP:0000389)1.64161341
141Prolonged bleeding time (HP:0003010)1.64042704
142Tracheoesophageal fistula (HP:0002575)1.63939406
143Entropion (HP:0000621)1.63088634
144Abnormality of B cell number (HP:0010975)1.62024732
145B lymphocytopenia (HP:0010976)1.62024732
146Skin ulcer (HP:0200042)1.61905417
147Abnormality of the ileum (HP:0001549)1.61720236
148Dysostosis multiplex (HP:0000943)1.60827316
149Increased neuronal autofluorescent lipopigment (HP:0002074)1.59998600
150Abnormal protein N-linked glycosylation (HP:0012347)1.59378688
151Abnormal glycosylation (HP:0012345)1.59378688

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK32.96902307
2NME22.86858501
3TESK22.52068221
4MAP4K12.46381191
5IRAK42.39411164
6TNK22.31407915
7VRK22.19092599
8KIT2.17931278
9BLK2.14576327
10WEE12.14252924
11EPHA22.08532114
12MAP2K32.08027722
13FES2.02427837
14FLT31.97036602
15ZAP701.96430986
16TAOK11.95121658
17TXK1.81718369
18TYK21.76961734
19FGR1.72452805
20TAOK21.71030911
21MAP3K141.66918807
22TBK11.65459220
23BUB11.62195882
24ERN11.59570063
25TGFBR21.57912052
26CDK121.53281362
27JAK31.52788983
28MATK1.52647411
29MAPKAPK31.48276350
30IKBKB1.46263669
31PIM21.45427252
32CSF1R1.42022789
33PIM11.41714583
34STK101.41407036
35RPS6KB21.39861788
36TEC1.39261113
37PAK41.35070069
38BTK1.34937943
39CDK71.34402264
40TGFBR11.32572158
41STK41.32174126
42ZAK1.31729261
43KDR1.29219374
44TESK11.28566181
45NEK21.26779757
46PRPF4B1.25189844
47TTK1.24969065
48BRSK21.22171761
49SMG11.19111742
50STK161.18764998
51TIE11.16231617
52CLK11.15854348
53RPS6KA41.13488191
54CDK191.12053554
55IKBKE1.10151151
56MAP3K11.07947837
57ARAF1.05855377
58SIK31.05752896
59PLK41.04470117
60LRRK21.01995122
61SRPK11.01020969
62MAP3K111.00453500
63DYRK30.97888458
64ACVR1B0.97717873
65CSK0.96443882
66EIF2AK30.95903601
67EIF2AK10.93620551
68EEF2K0.93510581
69TTN0.93339752
70YES10.92023666
71ATR0.91146588
72CDK40.90876468
73NEK90.90792339
74MAP3K60.88308698
75PTK60.87141833
76CHUK0.86546406
77NEK10.86482598
78PASK0.85720492
79HCK0.81988428
80BMX0.79417136
81JAK20.77524952
82MARK30.77434688
83ABL20.76830958
84STK30.76475658
85PLK10.76237384
86MAP2K60.75187872
87AURKB0.75101626
88PRKD20.74986861
89LCK0.74934843
90CDC70.74756193
91LYN0.72321237
92GRK70.72181785
93PKN20.71866276
94TLK10.71667958
95VRK10.70539486
96SYK0.70416187
97NLK0.70211776
98IRAK20.69219083
99NME10.68993928
100MAP3K80.67356067
101PRKG20.66938848
102PAK10.66781803
103TAOK30.66610562
104RPS6KL10.65992970
105RPS6KC10.65992970
106RPS6KA60.63625277
107EIF2AK20.63460339
108PBK0.62762084
109MAP3K50.61022676
110ITK0.59963028
111SCYL20.59533088
112RIPK10.57388946
113MYLK0.57306279
114MAP3K30.57268669
115EPHB10.56005840
116BCKDK0.53697496
117MAP3K130.53346346
118PTK2B0.53008860
119IRAK10.52472302
120TRPM70.52147877
121SIK10.49200291
122RIPK40.48541266
123KSR20.47664735
124JAK10.46515165
125TRIB30.45372828
126PDPK10.44932943
127GRK60.44678362
128PDK20.44615240
129MST40.44354423
130AKT30.43939583
131BMPR20.43891060
132MAPKAPK20.43462977
133MKNK20.43174387
134FYN0.41058316
135CHEK20.40872644
136MOS0.40003690
137LIMK10.39258881
138PRKCD0.38802409
139PDK10.38656011
140DAPK10.38021842
141RAF10.37922220
142PRKCQ0.33736412
143MARK20.29581563
144CDC42BPA0.26069724
145BRAF0.25701388

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.18793958
2Ribosome_Homo sapiens_hsa030103.00661373
3Mismatch repair_Homo sapiens_hsa034302.79387242
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.30283201
5Leishmaniasis_Homo sapiens_hsa051402.16333722
6Base excision repair_Homo sapiens_hsa034102.15299805
7Other glycan degradation_Homo sapiens_hsa005112.14829667
8Homologous recombination_Homo sapiens_hsa034402.12066643
9Proteasome_Homo sapiens_hsa030502.02944487
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.97380366
11Legionellosis_Homo sapiens_hsa051341.91568866
12RNA polymerase_Homo sapiens_hsa030201.87644651
13NF-kappa B signaling pathway_Homo sapiens_hsa040641.78778486
14Spliceosome_Homo sapiens_hsa030401.65930291
15Nucleotide excision repair_Homo sapiens_hsa034201.55539500
16Antigen processing and presentation_Homo sapiens_hsa046121.55096644
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.55074157
18Pyrimidine metabolism_Homo sapiens_hsa002401.53233342
19Herpes simplex infection_Homo sapiens_hsa051681.52619000
20RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.50559204
21RNA transport_Homo sapiens_hsa030131.50452290
22Fanconi anemia pathway_Homo sapiens_hsa034601.45125223
23Measles_Homo sapiens_hsa051621.43319586
24p53 signaling pathway_Homo sapiens_hsa041151.40402312
25Oxidative phosphorylation_Homo sapiens_hsa001901.39685490
26Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.39651656
27Type I diabetes mellitus_Homo sapiens_hsa049401.39232353
28Allograft rejection_Homo sapiens_hsa053301.36584588
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.36040743
30Hematopoietic cell lineage_Homo sapiens_hsa046401.35167126
31One carbon pool by folate_Homo sapiens_hsa006701.33716277
32Pertussis_Homo sapiens_hsa051331.33049660
33Primary immunodeficiency_Homo sapiens_hsa053401.32703988
34Toll-like receptor signaling pathway_Homo sapiens_hsa046201.30824958
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.25403621
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.24258125
37Staphylococcus aureus infection_Homo sapiens_hsa051501.21770394
38Cell cycle_Homo sapiens_hsa041101.19567497
39Non-homologous end-joining_Homo sapiens_hsa034501.17808491
40Intestinal immune network for IgA production_Homo sapiens_hsa046721.17487110
41Parkinsons disease_Homo sapiens_hsa050121.16192224
42Graft-versus-host disease_Homo sapiens_hsa053321.15895619
43Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.15576345
44Malaria_Homo sapiens_hsa051441.14747006
45Asthma_Homo sapiens_hsa053101.13275514
46Lysosome_Homo sapiens_hsa041421.12993796
47Apoptosis_Homo sapiens_hsa042101.12475306
48Influenza A_Homo sapiens_hsa051641.12195253
49Osteoclast differentiation_Homo sapiens_hsa043801.09551035
50Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.05488750
51Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.03672187
52Toxoplasmosis_Homo sapiens_hsa051450.99275253
53Epstein-Barr virus infection_Homo sapiens_hsa051690.98321968
54Arachidonic acid metabolism_Homo sapiens_hsa005900.96997820
55Tuberculosis_Homo sapiens_hsa051520.96925449
56Jak-STAT signaling pathway_Homo sapiens_hsa046300.96865924
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.95195168
58Shigellosis_Homo sapiens_hsa051310.94965832
59Collecting duct acid secretion_Homo sapiens_hsa049660.93722465
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90829424
61Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.90166388
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89006956
63TNF signaling pathway_Homo sapiens_hsa046680.85685160
64Fatty acid elongation_Homo sapiens_hsa000620.84211064
65RNA degradation_Homo sapiens_hsa030180.83787146
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.83132874
67Acute myeloid leukemia_Homo sapiens_hsa052210.82551071
68Pentose phosphate pathway_Homo sapiens_hsa000300.81243059
69Galactose metabolism_Homo sapiens_hsa000520.81185178
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.80297342
71Folate biosynthesis_Homo sapiens_hsa007900.79549654
72Huntingtons disease_Homo sapiens_hsa050160.79431210
73Salmonella infection_Homo sapiens_hsa051320.79290408
74Viral myocarditis_Homo sapiens_hsa054160.78601705
75Small cell lung cancer_Homo sapiens_hsa052220.76562112
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75073682
77Fructose and mannose metabolism_Homo sapiens_hsa000510.73549407
78Basal transcription factors_Homo sapiens_hsa030220.73338845
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.71189793
80Purine metabolism_Homo sapiens_hsa002300.70361358
81B cell receptor signaling pathway_Homo sapiens_hsa046620.67031205
82Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.66212166
83Notch signaling pathway_Homo sapiens_hsa043300.65740369
84Viral carcinogenesis_Homo sapiens_hsa052030.65145810
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64285728
86T cell receptor signaling pathway_Homo sapiens_hsa046600.62100433
87Hepatitis B_Homo sapiens_hsa051610.61980525
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.60434621
89Alzheimers disease_Homo sapiens_hsa050100.59987805
90HTLV-I infection_Homo sapiens_hsa051660.59792874
91Endocytosis_Homo sapiens_hsa041440.59367981
92Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58704993
93Regulation of autophagy_Homo sapiens_hsa041400.56706959
94Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53974081
95Autoimmune thyroid disease_Homo sapiens_hsa053200.52386436
96Glutathione metabolism_Homo sapiens_hsa004800.51059112
97Phagosome_Homo sapiens_hsa041450.49412918
98Rheumatoid arthritis_Homo sapiens_hsa053230.49000925
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.48701045
100N-Glycan biosynthesis_Homo sapiens_hsa005100.48230095
101Thyroid cancer_Homo sapiens_hsa052160.47335476
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46814957
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46803201
104African trypanosomiasis_Homo sapiens_hsa051430.45310107
105Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.44861309
106Chronic myeloid leukemia_Homo sapiens_hsa052200.43144285
107mRNA surveillance pathway_Homo sapiens_hsa030150.41816573
108Hepatitis C_Homo sapiens_hsa051600.41189088
109HIF-1 signaling pathway_Homo sapiens_hsa040660.40926632
110Sulfur relay system_Homo sapiens_hsa041220.40802263
111Vibrio cholerae infection_Homo sapiens_hsa051100.40076991
112Systemic lupus erythematosus_Homo sapiens_hsa053220.38416128
113Amoebiasis_Homo sapiens_hsa051460.37933753
114Chemokine signaling pathway_Homo sapiens_hsa040620.37870865
115Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.37524638
116Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37254413
117Renin-angiotensin system_Homo sapiens_hsa046140.37012993
118Platelet activation_Homo sapiens_hsa046110.34931249
119Carbon metabolism_Homo sapiens_hsa012000.30765675
120Pancreatic cancer_Homo sapiens_hsa052120.29344471
121Bladder cancer_Homo sapiens_hsa052190.28978109

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »