AHNAK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.98314074
2cell adhesion mediated by integrin (GO:0033627)4.92818398
3apoptotic cell clearance (GO:0043277)4.66267816
4hemidesmosome assembly (GO:0031581)4.62229736
5neuron projection extension involved in neuron projection guidance (GO:1902284)4.08207697
6axon extension involved in axon guidance (GO:0048846)4.08207697
7plasma membrane repair (GO:0001778)3.86335441
8regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.80159899
9wound healing, spreading of epidermal cells (GO:0035313)3.75533517
10positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.72104183
11regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.69834431
12endodermal cell differentiation (GO:0035987)3.61643064
13hypotonic response (GO:0006971)3.57371026
14positive regulation of p38MAPK cascade (GO:1900745)3.56835864
15regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.49256333
16substrate-dependent cell migration (GO:0006929)3.44023088
17collagen fibril organization (GO:0030199)3.39452790
18regulation of integrin activation (GO:0033623)3.38908599
19vascular endothelial growth factor signaling pathway (GO:0038084)3.33256474
20cell-substrate junction assembly (GO:0007044)3.32878258
21negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.32283267
22negative regulation of cell killing (GO:0031342)3.32283267
23positive regulation of receptor recycling (GO:0001921)3.22586522
24glomerular visceral epithelial cell development (GO:0072015)3.12318924
25cellular response to interferon-alpha (GO:0035457)2.99757448
26embryonic process involved in female pregnancy (GO:0060136)2.98107823
27positive regulation by symbiont of host defense response (GO:0052509)2.96838030
28modulation by symbiont of host defense response (GO:0052031)2.96838030
29modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.96838030
30modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.96838030
31positive regulation by organism of defense response of other organism involved in symbiotic interact2.96838030
32modulation by symbiont of host immune response (GO:0052553)2.96838030
33protein localization to endosome (GO:0036010)2.96321934
34fibroblast migration (GO:0010761)2.94492142
35protein heterotrimerization (GO:0070208)2.93019111
36skin morphogenesis (GO:0043589)2.89156870
37cortical actin cytoskeleton organization (GO:0030866)2.85549545
38histone H3-K36 demethylation (GO:0070544)2.85194879
39low-density lipoprotein particle clearance (GO:0034383)2.82990662
40cellular extravasation (GO:0045123)2.81505349
41chondrocyte proliferation (GO:0035988)2.81310026
42antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.80999465
43wound healing, spreading of cells (GO:0044319)2.80987380
44response to fluid shear stress (GO:0034405)2.80131240
45negative regulation of erythrocyte differentiation (GO:0045647)2.79770739
46regulation of interferon-beta biosynthetic process (GO:0045357)2.79565778
47regulation of gamma-delta T cell differentiation (GO:0045586)2.78955553
48regulation of necroptotic process (GO:0060544)2.78478965
49sequestering of extracellular ligand from receptor (GO:0035581)2.78458569
50regulation of gamma-delta T cell activation (GO:0046643)2.77527904
51insulin-like growth factor receptor signaling pathway (GO:0048009)2.77224954
52heterotypic cell-cell adhesion (GO:0034113)2.74832038
53negative regulation of granulocyte differentiation (GO:0030853)2.74415152
54positive regulation of gamma-delta T cell activation (GO:0046645)2.73731663
55response to muramyl dipeptide (GO:0032495)2.73492165
56membrane raft organization (GO:0031579)2.72415571
57cytoplasmic mRNA processing body assembly (GO:0033962)2.71545908
58phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.71207579
59natural killer cell mediated immunity (GO:0002228)2.71005288
60natural killer cell mediated cytotoxicity (GO:0042267)2.71005288
61growth hormone receptor signaling pathway (GO:0060396)2.70421617
62retina vasculature morphogenesis in camera-type eye (GO:0061299)2.69557167
63glomerular epithelial cell development (GO:0072310)2.68912144
64regulation of p38MAPK cascade (GO:1900744)2.67827468
65I-kappaB phosphorylation (GO:0007252)2.67754859
66desmosome organization (GO:0002934)2.67581518
67positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.67166091
68antigen processing and presentation of endogenous antigen (GO:0019883)2.63936453
69regulation of interleukin-12 biosynthetic process (GO:0045075)2.61332609
70negative regulation of smooth muscle cell migration (GO:0014912)2.61164833
71detection of molecule of bacterial origin (GO:0032490)2.60160485
72protein localization to cell surface (GO:0034394)2.60036352
73negative regulation of anoikis (GO:2000811)2.59579364
74response to laminar fluid shear stress (GO:0034616)2.59395752
75substrate adhesion-dependent cell spreading (GO:0034446)2.59054778
76detection of other organism (GO:0098543)2.57034812
77antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.56875710
78NLS-bearing protein import into nucleus (GO:0006607)2.56153851
79basement membrane organization (GO:0071711)2.55598180
80negative regulation of fatty acid transport (GO:2000192)2.54384497
81collagen metabolic process (GO:0032963)2.53670961
82negative thymic T cell selection (GO:0045060)2.52828940
83platelet-derived growth factor receptor signaling pathway (GO:0048008)2.52393992
84positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.52169553
85mannose metabolic process (GO:0006013)2.52129495
86pinocytosis (GO:0006907)2.51973088
87cellular response to ethanol (GO:0071361)2.51941279
88cytoskeletal anchoring at plasma membrane (GO:0007016)2.51569726
89integrin-mediated signaling pathway (GO:0007229)2.51260787
90positive thymic T cell selection (GO:0045059)2.49398246
91dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.48856932
92negative T cell selection (GO:0043383)2.47561020
93collagen catabolic process (GO:0030574)2.46332111
94semaphorin-plexin signaling pathway (GO:0071526)2.45256426
95mesodermal cell differentiation (GO:0048333)2.44865478
96positive T cell selection (GO:0043368)2.44786723
97multicellular organismal macromolecule metabolic process (GO:0044259)2.43629198
98surfactant homeostasis (GO:0043129)2.43438346
99regulation of B cell receptor signaling pathway (GO:0050855)2.43109003
100positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.42905244
101positive regulation of natural killer cell differentiation (GO:0032825)2.42769038
102negative regulation of lipid storage (GO:0010888)2.42140009
103cortical cytoskeleton organization (GO:0030865)2.42133006
104renal filtration (GO:0097205)2.41846992
105iron ion import (GO:0097286)2.40992698
106cellular response to vitamin (GO:0071295)2.40826830
107cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.39636595
108regulation of membrane protein ectodomain proteolysis (GO:0051043)2.39305260
109regulation of extracellular matrix disassembly (GO:0010715)2.38699957
110regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.38581755
111mesenchymal-epithelial cell signaling (GO:0060638)2.38488927
112barbed-end actin filament capping (GO:0051016)2.38475899
113hepatocyte apoptotic process (GO:0097284)2.38471684
114cellular response to epinephrine stimulus (GO:0071872)2.36735180
115cell-substrate adherens junction assembly (GO:0007045)2.35255639
116focal adhesion assembly (GO:0048041)2.35255639
117positive regulation of Cdc42 GTPase activity (GO:0043089)2.34188522
118detection of external biotic stimulus (GO:0098581)2.33916361
119regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.33695904
120positive regulation of cholesterol efflux (GO:0010875)2.33516283
121regulation of tight junction assembly (GO:2000810)2.33456264
122stress fiber assembly (GO:0043149)2.31432108
123negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.30524328
124nuclear pore complex assembly (GO:0051292)2.29872073
125multicellular organismal metabolic process (GO:0044236)2.29695289
126regulation of histone H3-K27 methylation (GO:0061085)2.29411568
127positive regulation of endothelial cell apoptotic process (GO:2000353)2.28872545
128adherens junction assembly (GO:0034333)2.28413015
129Notch signaling involved in heart development (GO:0061314)2.27977858
130multicellular organismal catabolic process (GO:0044243)2.27000331
131mRNA transcription (GO:0009299)2.26852184
132cellular response to growth hormone stimulus (GO:0071378)2.26071006
133positive regulation of interferon-alpha production (GO:0032727)2.25968927
134detection of bacterium (GO:0016045)2.25863475
135regulation of protein polyubiquitination (GO:1902914)2.25602400
136extracellular matrix disassembly (GO:0022617)2.25349674
137macrophage activation involved in immune response (GO:0002281)2.25291626
138T cell selection (GO:0045058)2.25009018
139fibril organization (GO:0097435)2.24666476
140negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.24568321
141regulation of anoikis (GO:2000209)2.22918143
142negative regulation of T cell mediated immunity (GO:0002710)2.21027100
143leukocyte aggregation (GO:0070486)2.20123698
144thymic T cell selection (GO:0045061)2.19834167
145lipid translocation (GO:0034204)2.19652411
146phospholipid translocation (GO:0045332)2.19652411
147antigen processing and presentation via MHC class Ib (GO:0002475)2.17265135
148regulation of ARF protein signal transduction (GO:0032012)2.17157707
149extracellular matrix assembly (GO:0085029)2.14917887
150import into cell (GO:0098657)2.12996748
151positive regulation of blood vessel endothelial cell migration (GO:0043536)2.12420657
152negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.12184044
153regulation of macrophage cytokine production (GO:0010935)2.10420816
154membrane protein ectodomain proteolysis (GO:0006509)2.09789272
155pericardium development (GO:0060039)2.09534743
156positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.08369769
157positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.08365956
158positive regulation of extracellular matrix organization (GO:1903055)2.07863186
159JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.07783236

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.71734493
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.03285798
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.42309407
4TRIM28_21343339_ChIP-Seq_HEK293_Human2.99044137
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.81882494
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.80569509
7RARG_19884340_ChIP-ChIP_MEFs_Mouse2.76926161
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.69838850
9Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.65106094
10SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.46904042
11STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.28239332
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.25671625
13CLOCK_20551151_ChIP-Seq_293T_Human2.18832100
14GATA2_21666600_ChIP-Seq_HMVEC_Human2.08514861
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.07790400
16* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.06605613
17* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.06605613
18TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.04299919
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.02338606
20PPAR_26484153_Chip-Seq_NCI-H1993_Human2.02274015
21SMAD_19615063_ChIP-ChIP_OVARY_Human2.01999728
22CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.00334136
23CJUN_26792858_Chip-Seq_BT549_Human2.00240331
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.98760612
25CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.98259500
26IRF8_27001747_Chip-Seq_BMDM_Mouse1.98189622
27* FOXO3_23340844_ChIP-Seq_DLD1_Human1.97977941
28ESR1_21235772_ChIP-Seq_MCF-7_Human1.97483894
29* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.94953575
30BRD4_25478319_ChIP-Seq_HGPS_Human1.93234572
31* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.92890874
32IRF8_21731497_ChIP-ChIP_J774_Mouse1.89888380
33* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.89500929
34* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.88660902
35ESR1_20079471_ChIP-ChIP_T-47D_Human1.87892968
36* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.68641323
37* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.65344429
38* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.62473097
39BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.62302898
40SCL_19346495_ChIP-Seq_HPC-7_Human1.61691021
41ESR2_21235772_ChIP-Seq_MCF-7_Human1.61076095
42* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.60964411
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.60875007
44CDX2_19796622_ChIP-Seq_MESCs_Mouse1.59534702
45* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.59109060
46TP53_16413492_ChIP-PET_HCT116_Human1.57025364
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.53946110
48IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.51532811
49FOXM1_23109430_ChIP-Seq_U2OS_Human1.50462956
50* ELK3_25401928_ChIP-Seq_HUVEC_Human1.47365791
51VDR_24787735_ChIP-Seq_THP-1_Human1.47365447
52SPI1_23127762_ChIP-Seq_K562_Human1.46091657
53WT1_19549856_ChIP-ChIP_CCG9911_Human1.44733620
54GATA1_19941826_ChIP-Seq_K562_Human1.44330363
55* EP300_21415370_ChIP-Seq_HL-1_Mouse1.43942828
56SALL1_21062744_ChIP-ChIP_HESCs_Human1.43077802
57BP1_19119308_ChIP-ChIP_Hs578T_Human1.42994375
58MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.42806715
59NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.42653564
60NRF2_20460467_ChIP-Seq_MEFs_Mouse1.42653564
61RUNX_20019798_ChIP-Seq_JUKART_Human1.41170801
62P300_27058665_Chip-Seq_ZR-75-30cells_Human1.36368868
63NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.34410614
64* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.33021957
65JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.32668534
66NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.30882757
67JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.30625203
68GATA1_22025678_ChIP-Seq_K562_Human1.30371714
69UBF1/2_26484160_Chip-Seq_HMECs_Human1.24819128
70* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.24500730
71TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24026367
72* KDM2B_26808549_Chip-Seq_JURKAT_Human1.23298790
73* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.23031716
74CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.20526908
75* TCF7_22412390_ChIP-Seq_EML_Mouse1.20340255
76KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.20230565
77NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.19701571
78SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19067901
79TCF4_18268006_ChIP-ChIP_LS174T_Human1.18883023
80STAT6_21828071_ChIP-Seq_BEAS2B_Human1.18865077
81TBX20_22328084_ChIP-Seq_HEART_Mouse1.18560173
82TBX20_22080862_ChIP-Seq_HEART_Mouse1.18560173
83* GATA1_19941827_ChIP-Seq_MEL_Mouse1.18430903
84CTNNB1_20460455_ChIP-Seq_HCT116_Human1.18359819
85* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17949198
86* GATA2_19941826_ChIP-Seq_K562_Human1.17428726
87RUNX1_22412390_ChIP-Seq_EML_Mouse1.16097896
88AHR_22903824_ChIP-Seq_MCF-7_Human1.15677974
89PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14511542
90* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.14384147
91* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.14317487
92* SOX2_20726797_ChIP-Seq_SW620_Human1.14218091
93ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.13577519
94* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.13522875
95MYB_26560356_Chip-Seq_TH1_Human1.12616263
96* MYB_26560356_Chip-Seq_TH2_Human1.12598771
97SOX2_27498859_Chip-Seq_STOMACH_Mouse1.12055248
98FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11684354
99SALL4_18804426_ChIP-ChIP_XEN_Mouse1.10549875
100VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10469299
101ATF3_27146783_Chip-Seq_COLON_Human1.10041703
102PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09027586
103PU_27001747_Chip-Seq_BMDM_Mouse1.08814044
104RUNX1_27514584_Chip-Seq_MCF-7_Human1.08728341
105VDR_24763502_ChIP-Seq_THP-1_Human1.08156384
106* KDM2B_26808549_Chip-Seq_K562_Human1.06687922
107* KDM2B_26808549_Chip-Seq_DND41_Human1.05739065
108PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.04998230
109* FOXA2_19822575_ChIP-Seq_HepG2_Human1.04545523
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.04244582
111ARNT_22903824_ChIP-Seq_MCF-7_Human1.03949485
112RXR_22108803_ChIP-Seq_LS180_Human1.02967385
113NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.01535758
114TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01146108
115* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00915030
116* MAF_26560356_Chip-Seq_TH1_Human1.00388655
117* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99252679
118SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97618322
119VDR_21846776_ChIP-Seq_THP-1_Human0.97383938
120NFIB_24661679_ChIP-Seq_LUNG_Mouse0.97042849

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.82278983
2MP0000569_abnormal_digit_pigmentation4.82880057
3MP0005275_abnormal_skin_tensile4.07623397
4MP0003705_abnormal_hypodermis_morpholog3.92822820
5MP0001958_emphysema2.92637509
6MP0003566_abnormal_cell_adhesion2.73046228
7MP0003300_gastrointestinal_ulcer2.67916560
8MP0003091_abnormal_cell_migration2.36229511
9MP0010352_gastrointestinal_tract_polyps2.35909891
10MP0003279_aneurysm2.33392728
11MP0002060_abnormal_skin_morphology2.17875752
12MP0003191_abnormal_cellular_cholesterol2.14097394
13MP0005076_abnormal_cell_differentiation2.06329402
14MP0008260_abnormal_autophagy2.02587396
15MP0002166_altered_tumor_susceptibility2.00544173
16MP0005409_darkened_coat_color1.98203020
17MP0005503_abnormal_tendon_morphology1.94995786
18MP0003045_fibrosis1.90980365
19MP0004272_abnormal_basement_membrane1.90836598
20MP0003763_abnormal_thymus_physiology1.85775527
21MP0005023_abnormal_wound_healing1.84967070
22MP0005451_abnormal_body_composition1.83228712
23MP0009278_abnormal_bone_marrow1.78547595
24MP0000733_abnormal_muscle_development1.74753751
25MP0004883_abnormal_blood_vessel1.62137515
26MP0002006_tumorigenesis1.60486901
27MP0005257_abnormal_intraocular_pressure1.53716636
28MP0002009_preneoplasia1.52681564
29MP0001243_abnormal_dermal_layer1.52329498
30MP0004947_skin_inflammation1.52131323
31MP0005164_abnormal_response_to1.50794860
32MP0005623_abnormal_meninges_morphology1.49780340
33MP0003303_peritoneal_inflammation1.46429077
34MP0000767_abnormal_smooth_muscle1.40577216
35MP0004185_abnormal_adipocyte_glucose1.28431479
36MP0002168_other_aberrant_phenotype1.27805198
37MP0003448_altered_tumor_morphology1.27634561
38MP0005058_abnormal_lysosome_morphology1.27577826
39MP0004381_abnormal_hair_follicle1.26526107
40MP0002877_abnormal_melanocyte_morpholog1.25915038
41MP0010234_abnormal_vibrissa_follicle1.24608889
42MP0010307_abnormal_tumor_latency1.23663067
43MP0002332_abnormal_exercise_endurance1.20700656
44MP0001299_abnormal_eye_distance/1.20218417
45MP0010368_abnormal_lymphatic_system1.17529343
46MP0003828_pulmonary_edema1.16628889
47MP0003453_abnormal_keratinocyte_physiol1.13316517
48MP0002998_abnormal_bone_remodeling1.12185268
49MP0003950_abnormal_plasma_membrane1.12000231
50MP0002254_reproductive_system_inflammat1.10731064
51MP0000751_myopathy1.10599262
52MP0004510_myositis1.09279277
53MP0004264_abnormal_extraembryonic_tissu1.08620346
54MP0001533_abnormal_skeleton_physiology1.06121369
55MP0003436_decreased_susceptibility_to1.05734090
56MP0000371_diluted_coat_color1.04142197
57MP0004130_abnormal_muscle_cell1.02915270
58MP0002933_joint_inflammation1.02611465
59MP0009384_cardiac_valve_regurgitation1.01976717
60MP0000383_abnormal_hair_follicle1.01473776
61MP0003656_abnormal_erythrocyte_physiolo1.01308196
62MP0002405_respiratory_system_inflammati0.98036187
63MP0002896_abnormal_bone_mineralization0.97764567
64MP0000750_abnormal_muscle_regeneration0.97740390
65MP0005508_abnormal_skeleton_morphology0.97654456
66MP0001800_abnormal_humoral_immune0.97399646
67MP0005397_hematopoietic_system_phenotyp0.96503800
68MP0001545_abnormal_hematopoietic_system0.96503800
69MP0000685_abnormal_immune_system0.96328118
70MP0000249_abnormal_blood_vessel0.95458604
71MP0005174_abnormal_tail_pigmentation0.95404509
72MP0010678_abnormal_skin_adnexa0.95153503
73MP0000749_muscle_degeneration0.93163464
74MP0002419_abnormal_innate_immunity0.92438803
75MP0003172_abnormal_lysosome_physiology0.92195919
76MP0006138_congestive_heart_failure0.92061914
77MP0001835_abnormal_antigen_presentation0.92021499
78MP0009780_abnormal_chondrocyte_physiolo0.91637129
79MP0006054_spinal_hemorrhage0.91252861
80MP0010630_abnormal_cardiac_muscle0.90888715
81MP0002796_impaired_skin_barrier0.90594773
82MP0000858_altered_metastatic_potential0.90237894
83MP0005390_skeleton_phenotype0.89864850
84MP0003724_increased_susceptibility_to0.89698243
85MP0005666_abnormal_adipose_tissue0.89369658
86MP0005595_abnormal_vascular_smooth0.88887491
87MP0004808_abnormal_hematopoietic_stem0.88704068
88MP0001879_abnormal_lymphatic_vessel0.86872881
89MP0001915_intracranial_hemorrhage0.86463951
90MP0000015_abnormal_ear_pigmentation0.86159110
91MP0001849_ear_inflammation0.86140913
92MP0002295_abnormal_pulmonary_circulatio0.85816424
93* MP0005025_abnormal_response_to0.85765658
94MP0010155_abnormal_intestine_physiology0.84766379
95MP0005501_abnormal_skin_physiology0.84438496
96MP0004087_abnormal_muscle_fiber0.83574095
97MP0003690_abnormal_glial_cell0.83405154
98MP0001873_stomach_inflammation0.83237536
99* MP0002420_abnormal_adaptive_immunity0.82607864
100MP0006082_CNS_inflammation0.82115199
101MP0005171_absent_coat_pigmentation0.82061734
102MP0008004_abnormal_stomach_pH0.81609834
103MP0002108_abnormal_muscle_morphology0.81503402
104MP0000427_abnormal_hair_cycle0.81476489
105* MP0001819_abnormal_immune_cell0.81467839
106MP0002133_abnormal_respiratory_system0.80685379
107MP0005388_respiratory_system_phenotype0.80685379
108MP0005375_adipose_tissue_phenotype0.79577638
109MP0003329_amyloid_beta_deposits0.79440944
110MP0005387_immune_system_phenotype0.77692125
111MP0001790_abnormal_immune_system0.77692125
112MP0000013_abnormal_adipose_tissue0.77384590
113MP0000604_amyloidosis0.77254034
114MP0002128_abnormal_blood_circulation0.76676542
115MP0002925_abnormal_cardiovascular_devel0.76605372
116MP0001542_abnormal_bone_strength0.76143075
117MP0002452_abnormal_antigen_presenting0.75050766
118MP0000627_abnormal_mammary_gland0.74941960
119MP0000465_gastrointestinal_hemorrhage0.74563513
120MP0001216_abnormal_epidermal_layer0.73997114
121MP0001191_abnormal_skin_condition0.72960557
122MP0000003_abnormal_adipose_tissue0.72074788
123MP0005197_abnormal_uvea_morphology0.71952598
124MP0005464_abnormal_platelet_physiology0.71835612
125MP0001851_eye_inflammation0.70754154
126MP0002396_abnormal_hematopoietic_system0.70660677
127MP0001614_abnormal_blood_vessel0.69939557
128MP0005000_abnormal_immune_tolerance0.69615020
129MP0010771_integument_phenotype0.68579305
130MP0004084_abnormal_cardiac_muscle0.68277630
131MP0005621_abnormal_cell_physiology0.67765101
132MP0003795_abnormal_bone_structure0.66641305

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.83218225
2Ankle contracture (HP:0006466)4.36243322
3Increased connective tissue (HP:0009025)4.30569288
4Protrusio acetabuli (HP:0003179)4.30190944
5Cerebral aneurysm (HP:0004944)3.98213133
6Osteolytic defects of the phalanges of the hand (HP:0009771)3.97535962
7Osteolytic defects of the hand bones (HP:0009699)3.97535962
8Shallow orbits (HP:0000586)3.85599050
9Atrophic scars (HP:0001075)3.50116163
10Aortic dissection (HP:0002647)3.46858233
11Cervical subluxation (HP:0003308)3.44836607
12Aortic aneurysm (HP:0004942)3.38497954
13Absent frontal sinuses (HP:0002688)3.32776007
14Broad metatarsal (HP:0001783)3.28845015
15Dilatation of the ascending aorta (HP:0005111)3.18768753
16Eczematoid dermatitis (HP:0000976)3.18322599
17Thick nail (HP:0001805)3.14371460
18Distal lower limb amyotrophy (HP:0008944)3.14271476
19Mitral valve prolapse (HP:0001634)3.12855309
20Increased density of long bones (HP:0006392)3.05760498
21Fragile skin (HP:0001030)3.02398027
22Alopecia of scalp (HP:0002293)2.95365940
23Peritonitis (HP:0002586)2.89233898
24Hematochezia (HP:0002573)2.84571740
25Wrist flexion contracture (HP:0001239)2.82769441
26Short nail (HP:0001799)2.77835055
27Spinal cord lesions (HP:0100561)2.74391721
28Syringomyelia (HP:0003396)2.74391721
29Urethral obstruction (HP:0000796)2.72195796
30Difficulty climbing stairs (HP:0003551)2.65288078
31Myocardial infarction (HP:0001658)2.56342686
32Ulnar bowing (HP:0003031)2.55491970
33Recurrent bacterial skin infections (HP:0005406)2.51197921
34Radial bowing (HP:0002986)2.48344742
35Soft skin (HP:0000977)2.45348811
36Lower limb amyotrophy (HP:0007210)2.43374905
37Interstitial pulmonary disease (HP:0006530)2.39785644
38Type 1 muscle fiber predominance (HP:0003803)2.39205629
39Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.37790123
40Glucose intolerance (HP:0000833)2.34780629
41Wormian bones (HP:0002645)2.33137216
42Genu recurvatum (HP:0002816)2.33095605
43Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.31813874
44Spinal rigidity (HP:0003306)2.28686105
45Follicular hyperkeratosis (HP:0007502)2.26591210
46T lymphocytopenia (HP:0005403)2.25604464
47Gingivitis (HP:0000230)2.24993750
48Milia (HP:0001056)2.24185715
49Aneurysm (HP:0002617)2.23744659
50Mildly elevated creatine phosphokinase (HP:0008180)2.20510708
51Vertebral compression fractures (HP:0002953)2.19614628
52Spontaneous hematomas (HP:0007420)2.19493586
53Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.19043624
54Short 4th metacarpal (HP:0010044)2.19043624
55Broad face (HP:0000283)2.18338300
56Thin bony cortex (HP:0002753)2.16171376
57Persistence of primary teeth (HP:0006335)2.15019268
58Scapular winging (HP:0003691)2.14736723
59Hyporeflexia of lower limbs (HP:0002600)2.11269593
60Abnormality of the frontal sinuses (HP:0002687)2.09785667
61Bladder diverticulum (HP:0000015)2.08465677
62Long toe (HP:0010511)2.05363299
63Periodontitis (HP:0000704)2.05242013
64Spondylolisthesis (HP:0003302)2.05032336
65Abnormality of the fingertips (HP:0001211)2.04211146
66Tibial bowing (HP:0002982)2.03461646
67Flat acetabular roof (HP:0003180)2.02023401
68Abnormality of oral frenula (HP:0000190)2.00014515
69Abnormality of the radial head (HP:0003995)1.98439124
70Blue sclerae (HP:0000592)1.97785800
71Distal lower limb muscle weakness (HP:0009053)1.96988094
72Abnormal glucose tolerance (HP:0001952)1.96104885
73Abnormality of the nasal septum (HP:0000419)1.95835368
74Bowed forearm bones (HP:0003956)1.94909955
75Bowing of the arm (HP:0006488)1.94909955
76Striae distensae (HP:0001065)1.94365807
77Increased mean platelet volume (HP:0011877)1.94035586
78Abnormality of T cell number (HP:0011839)1.93814362
79Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.93630284
80Narrow palate (HP:0000189)1.93178715
81Frequent falls (HP:0002359)1.92860175
82Mitral regurgitation (HP:0001653)1.90570556
83Camptodactyly of toe (HP:0001836)1.89063359
84Muscle fiber splitting (HP:0003555)1.87918158
85Slender build (HP:0001533)1.87620223
86Abnormality of skeletal muscle fiber size (HP:0012084)1.87518291
87Elbow flexion contracture (HP:0002987)1.86197654
88Coarse hair (HP:0002208)1.85862758
89Colitis (HP:0002583)1.83856605
90Pulmonary artery stenosis (HP:0004415)1.83768216
91Cellulitis (HP:0100658)1.83664597
92Distal upper limb amyotrophy (HP:0007149)1.83595314
93Upper limb amyotrophy (HP:0009129)1.83595314
94Aortic regurgitation (HP:0001659)1.82929688
95Vascular tortuosity (HP:0004948)1.81915363
96Ankyloglossia (HP:0010296)1.81476252
97Submucous cleft hard palate (HP:0000176)1.81145629
98Hypoplasia of the iris (HP:0007676)1.79883289
99Broad ribs (HP:0000885)1.79151171
100Prostate neoplasm (HP:0100787)1.76241984
101Mesomelia (HP:0003027)1.75580675
102Difficulty running (HP:0009046)1.74984557
103Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.74753091
104Abnormal platelet volume (HP:0011876)1.74733794
105Arterial tortuosity (HP:0005116)1.74529767
106Increased IgE level (HP:0003212)1.73968708
107Abnormality of macrophages (HP:0004311)1.72326715
108Right ventricular cardiomyopathy (HP:0011663)1.71672515
109Delayed closure of the anterior fontanelle (HP:0001476)1.71594782
110Joint laxity (HP:0001388)1.71083263
111Subacute progressive viral hepatitis (HP:0006572)1.70062586
112Abnormality of the distal phalanges of the toes (HP:0010182)1.69944049
113Overgrowth (HP:0001548)1.69841107
114Cerebral inclusion bodies (HP:0100314)1.67662144
115Abnormality of the calcaneus (HP:0008364)1.67289927
116Amyloidosis (HP:0011034)1.66822752
117Mitral stenosis (HP:0001718)1.66304075
118Recurrent abscess formation (HP:0002722)1.65407354
119Abnormality of the distal phalanx of the thumb (HP:0009617)1.64252168
120Hypoplastic ischia (HP:0003175)1.64158887
121Bruising susceptibility (HP:0000978)1.62746792
122Increased variability in muscle fiber diameter (HP:0003557)1.61993517
123Abnormality of the 4th metacarpal (HP:0010012)1.61796026
124Gingival bleeding (HP:0000225)1.61779472
125Dislocated radial head (HP:0003083)1.60644929
126Natal tooth (HP:0000695)1.60478005
127Viral hepatitis (HP:0006562)1.59908743
128Advanced eruption of teeth (HP:0006288)1.58899713
129Long eyelashes (HP:0000527)1.57836044
130Abnormal ossification of hand bones (HP:0005921)1.57248371
131Recurrent skin infections (HP:0001581)1.57156571
132Gastrointestinal infarctions (HP:0005244)1.56898287
133Myositis (HP:0100614)1.56335453
134Recurrent gram-negative bacterial infections (HP:0005420)1.54326569

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN6.06053092
2RIPK12.87144819
3CAMK1D2.83859081
4TRIB32.69128936
5PRPF4B2.65971642
6DDR22.60795554
7LATS12.33004923
8TRPM72.30280717
9SIK12.15598246
10PDGFRA2.13812079
11CAMK1G2.02847645
12JAK11.98436200
13CDK121.94042478
14BLK1.81740945
15PTK61.67438821
16TGFBR21.65737339
17MAP3K141.63227709
18PDGFRB1.62459495
19TYK21.52986780
20JAK31.51946985
21DMPK1.43453747
22FRK1.43191823
23PKN21.42810774
24FGFR31.41523432
25EPHA21.41322635
26MAP3K61.40672224
27STK101.39924772
28STK31.33668701
29FGFR41.33512002
30NEK91.30466155
31CDC42BPA1.30244466
32PIK3CG1.29977444
33EPHB11.28505841
34SCYL21.28453076
35STK381.27766448
36ICK1.27349052
37WNK11.22815316
38KIT1.20867895
39CDK61.20315387
40BMX1.19861402
41PAK21.19292072
42LRRK21.17536840
43PTK21.15221886
44NUAK11.13344753
45EPHA31.12578144
46FER1.12493258
47TBK11.12335775
48AKT31.11505389
49RPS6KA41.08792798
50* MTOR1.06191702
51MAP3K101.03269363
52FGFR21.02575900
53MAP3K31.02039325
54MST1R1.01931003
55GRK61.01315175
56SGK21.01228616
57CSK0.98563960
58MYLK0.97628878
59CSF1R0.97424903
60MAP3K10.96740501
61PIK3CA0.95389297
62CHUK0.94794299
63BTK0.92863477
64EEF2K0.92591332
65FES0.91797677
66HCK0.90754903
67MET0.89104065
68PAK40.88454914
69BMPR20.88235303
70TAOK30.86178723
71MAPK70.85910498
72MOS0.85569659
73KSR20.85178138
74IKBKB0.85055665
75MAP2K30.81824717
76ITK0.80491476
77IKBKE0.76295302
78ERN10.74908934
79PRKCH0.74307982
80FGFR10.70092426
81LATS20.67457947
82MAP3K130.66571917
83PDPK10.66039943
84INSR0.63840833
85FGR0.63771956
86SIK20.63680709
87YES10.63671065
88MELK0.62466237
89ROCK10.61593319
90NLK0.60859971
91SGK4940.59353173
92SGK2230.59353173
93SYK0.58811433
94EGFR0.58384109
95MARK30.58189419
96SMG10.56926834
97MAPK120.56093224
98LCK0.56063362
99NEK60.55249408
100PDK10.54565619
101MAP4K10.53694129
102JAK20.53376021
103STK40.53096949
104GSK3A0.52565483
105ZAK0.52242266
106TEC0.52180576
107CAMKK20.51361594
108MAP3K20.49217617
109ZAP700.48941947
110SGK30.47730800
111PRKAA20.45965946
112PRKD10.44630581
113ABL10.44232064
114MAP3K70.44109405
115RIPK40.43122359
116MARK20.42358553
117EPHB20.41962211
118SRC0.41945040
119IGF1R0.41110152
120RET0.40145420
121LMTK20.39865006
122EIF2AK20.39512248
123RPS6KA20.39403044
124PTK2B0.39274376
125CDK90.37171360
126BRD40.35122619
127FYN0.33641788
128MAP3K80.30297292
129RPS6KL10.29563998
130RPS6KC10.29563998
131PRKD20.29295369
132PIM10.29069977

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.70264731
2Focal adhesion_Homo sapiens_hsa045102.22351239
3Small cell lung cancer_Homo sapiens_hsa052222.05860016
4Malaria_Homo sapiens_hsa051441.96130626
5Proteoglycans in cancer_Homo sapiens_hsa052051.90739752
6Caffeine metabolism_Homo sapiens_hsa002321.87873962
7Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.81720594
8Adherens junction_Homo sapiens_hsa045201.79715118
9Amoebiasis_Homo sapiens_hsa051461.71002032
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.68981922
11Osteoclast differentiation_Homo sapiens_hsa043801.68882096
12Toxoplasmosis_Homo sapiens_hsa051451.68705649
13Viral myocarditis_Homo sapiens_hsa054161.66401562
14Leishmaniasis_Homo sapiens_hsa051401.63064396
15Chronic myeloid leukemia_Homo sapiens_hsa052201.61451545
16Leukocyte transendothelial migration_Homo sapiens_hsa046701.61441648
17MicroRNAs in cancer_Homo sapiens_hsa052061.61230488
18Other glycan degradation_Homo sapiens_hsa005111.48409688
19TNF signaling pathway_Homo sapiens_hsa046681.45999699
20Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.45318155
21NF-kappa B signaling pathway_Homo sapiens_hsa040641.44188285
22Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.42803819
23Dilated cardiomyopathy_Homo sapiens_hsa054141.41169662
24Regulation of actin cytoskeleton_Homo sapiens_hsa048101.40775630
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.39298105
26Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.38935876
27Platelet activation_Homo sapiens_hsa046111.31744152
28Pancreatic cancer_Homo sapiens_hsa052121.27861942
29Apoptosis_Homo sapiens_hsa042101.27712797
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27257646
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.23776738
32Salmonella infection_Homo sapiens_hsa051321.21849463
33Toll-like receptor signaling pathway_Homo sapiens_hsa046201.21161088
34Shigellosis_Homo sapiens_hsa051311.19879740
35Measles_Homo sapiens_hsa051621.18660463
36B cell receptor signaling pathway_Homo sapiens_hsa046621.16975346
37Tuberculosis_Homo sapiens_hsa051521.14722453
38Pertussis_Homo sapiens_hsa051331.12709102
39Staphylococcus aureus infection_Homo sapiens_hsa051501.11508409
40Inositol phosphate metabolism_Homo sapiens_hsa005621.07708397
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.07593158
42Thyroid cancer_Homo sapiens_hsa052161.05175001
43Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04741641
44GnRH signaling pathway_Homo sapiens_hsa049121.04681634
45Adipocytokine signaling pathway_Homo sapiens_hsa049201.04482959
46Phagosome_Homo sapiens_hsa041451.04331797
47mTOR signaling pathway_Homo sapiens_hsa041501.02211129
48ErbB signaling pathway_Homo sapiens_hsa040121.01086411
49TGF-beta signaling pathway_Homo sapiens_hsa043501.00936277
50Insulin resistance_Homo sapiens_hsa049311.00917403
51Acute myeloid leukemia_Homo sapiens_hsa052210.99386650
52PI3K-Akt signaling pathway_Homo sapiens_hsa041510.98973573
53Influenza A_Homo sapiens_hsa051640.98762874
54Jak-STAT signaling pathway_Homo sapiens_hsa046300.98066745
55Hepatitis B_Homo sapiens_hsa051610.97799347
56Choline metabolism in cancer_Homo sapiens_hsa052310.97323036
57Prostate cancer_Homo sapiens_hsa052150.96414247
58Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.95563775
59Protein digestion and absorption_Homo sapiens_hsa049740.93099474
60Hematopoietic cell lineage_Homo sapiens_hsa046400.90049440
61Type II diabetes mellitus_Homo sapiens_hsa049300.86510559
62Viral carcinogenesis_Homo sapiens_hsa052030.86255443
63Melanoma_Homo sapiens_hsa052180.86132419
64Glioma_Homo sapiens_hsa052140.85844151
65HTLV-I infection_Homo sapiens_hsa051660.85530832
66Rap1 signaling pathway_Homo sapiens_hsa040150.84956713
67Lysosome_Homo sapiens_hsa041420.84499753
68Hepatitis C_Homo sapiens_hsa051600.84355002
69Lysine degradation_Homo sapiens_hsa003100.83720405
70T cell receptor signaling pathway_Homo sapiens_hsa046600.83553328
71Bladder cancer_Homo sapiens_hsa052190.82249037
72Legionellosis_Homo sapiens_hsa051340.82147237
73Pathways in cancer_Homo sapiens_hsa052000.82061771
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.81250172
75Dorso-ventral axis formation_Homo sapiens_hsa043200.80932583
76Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.79513678
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.78800964
78Antigen processing and presentation_Homo sapiens_hsa046120.78336533
79Renin-angiotensin system_Homo sapiens_hsa046140.77307334
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.77291392
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.76995013
82Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.76479743
83Estrogen signaling pathway_Homo sapiens_hsa049150.76425499
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75636869
85Renal cell carcinoma_Homo sapiens_hsa052110.75344675
86Glycosaminoglycan degradation_Homo sapiens_hsa005310.73746869
87Chemokine signaling pathway_Homo sapiens_hsa040620.73654833
88Insulin signaling pathway_Homo sapiens_hsa049100.73508036
89HIF-1 signaling pathway_Homo sapiens_hsa040660.73168879
90Endocytosis_Homo sapiens_hsa041440.73081605
91Notch signaling pathway_Homo sapiens_hsa043300.72940221
92Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72083137
93VEGF signaling pathway_Homo sapiens_hsa043700.70827412
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70698148
95FoxO signaling pathway_Homo sapiens_hsa040680.69500790
96Central carbon metabolism in cancer_Homo sapiens_hsa052300.68601096
97Endometrial cancer_Homo sapiens_hsa052130.67009527
98Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66989738
99Hippo signaling pathway_Homo sapiens_hsa043900.66456535
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.65706916
101Prolactin signaling pathway_Homo sapiens_hsa049170.65652610
102RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64608101
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63971203
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63823973
105Colorectal cancer_Homo sapiens_hsa052100.63219447
106MAPK signaling pathway_Homo sapiens_hsa040100.61308610
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60876441
108AMPK signaling pathway_Homo sapiens_hsa041520.60875617
109Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.60301484
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.60180455
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.60168282
112Non-small cell lung cancer_Homo sapiens_hsa052230.60153197
113Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60131273
114Long-term potentiation_Homo sapiens_hsa047200.59083938
115Ras signaling pathway_Homo sapiens_hsa040140.56301466
116Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.52722612

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