

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.37581388 |
| 2 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.98073711 |
| 3 | cellular response to leptin stimulus (GO:0044320) | 4.95973420 |
| 4 | negative regulation of cell killing (GO:0031342) | 4.57169706 |
| 5 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.57169706 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.50823304 |
| 7 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.42800526 |
| 8 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.40449602 |
| 9 | mannose metabolic process (GO:0006013) | 4.31862848 |
| 10 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.19096442 |
| 11 | positive thymic T cell selection (GO:0045059) | 4.14538847 |
| 12 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.14333247 |
| 13 | regulation of gamma-delta T cell activation (GO:0046643) | 4.13979263 |
| 14 | ribosomal small subunit assembly (GO:0000028) | 4.12045332 |
| 15 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.08063309 |
| 16 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.02492138 |
| 17 | ATP synthesis coupled proton transport (GO:0015986) | 3.94963297 |
| 18 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.94963297 |
| 19 | negative thymic T cell selection (GO:0045060) | 3.94755688 |
| 20 | response to leptin (GO:0044321) | 3.88234702 |
| 21 | B cell receptor signaling pathway (GO:0050853) | 3.86927359 |
| 22 | mitochondrion morphogenesis (GO:0070584) | 3.84673623 |
| 23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.82208804 |
| 24 | regulation of histone H3-K27 methylation (GO:0061085) | 3.77158356 |
| 25 | substrate-dependent cell migration (GO:0006929) | 3.71720370 |
| 26 | negative T cell selection (GO:0043383) | 3.71371387 |
| 27 | induction of positive chemotaxis (GO:0050930) | 3.66202689 |
| 28 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.66126089 |
| 29 | thymic T cell selection (GO:0045061) | 3.63879493 |
| 30 | respiratory electron transport chain (GO:0022904) | 3.62006494 |
| 31 | protein complex biogenesis (GO:0070271) | 3.61768187 |
| 32 | limb bud formation (GO:0060174) | 3.61137232 |
| 33 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.58665309 |
| 34 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.58665309 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 3.58665309 |
| 36 | GTP biosynthetic process (GO:0006183) | 3.55111522 |
| 37 | electron transport chain (GO:0022900) | 3.53879631 |
| 38 | positive regulation of granulocyte differentiation (GO:0030854) | 3.53051344 |
| 39 | positive T cell selection (GO:0043368) | 3.50239556 |
| 40 | detection of bacterium (GO:0016045) | 3.48646689 |
| 41 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.48342191 |
| 42 | dopamine transport (GO:0015872) | 3.47092861 |
| 43 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.46822634 |
| 44 | T cell selection (GO:0045058) | 3.45220472 |
| 45 | detection of other organism (GO:0098543) | 3.45204454 |
| 46 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.45112964 |
| 47 | response to muramyl dipeptide (GO:0032495) | 3.42460730 |
| 48 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.42244174 |
| 49 | histone H3-K36 demethylation (GO:0070544) | 3.41417820 |
| 50 | presynaptic membrane assembly (GO:0097105) | 3.40298477 |
| 51 | establishment of integrated proviral latency (GO:0075713) | 3.39512234 |
| 52 | cullin deneddylation (GO:0010388) | 3.38408015 |
| 53 | presynaptic membrane organization (GO:0097090) | 3.36766826 |
| 54 | startle response (GO:0001964) | 3.32129057 |
| 55 | germinal center formation (GO:0002467) | 3.31151312 |
| 56 | positive regulation of protein autophosphorylation (GO:0031954) | 3.30572201 |
| 57 | proteasome assembly (GO:0043248) | 3.29005549 |
| 58 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.24895518 |
| 59 | positive regulation of B cell differentiation (GO:0045579) | 3.20924438 |
| 60 | DNA damage response, detection of DNA damage (GO:0042769) | 3.20480466 |
| 61 | negative regulation of glucose import (GO:0046325) | 3.19899375 |
| 62 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.17433993 |
| 63 | activated T cell proliferation (GO:0050798) | 3.17327541 |
| 64 | positive regulation of Rap GTPase activity (GO:0032854) | 3.16597314 |
| 65 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.16153293 |
| 66 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.15744724 |
| 67 | neuron cell-cell adhesion (GO:0007158) | 3.15631164 |
| 68 | positive regulation of mitochondrial fission (GO:0090141) | 3.12692554 |
| 69 | response to interleukin-15 (GO:0070672) | 3.12416165 |
| 70 | intraciliary transport (GO:0042073) | 3.12033246 |
| 71 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.07292193 |
| 72 | protein deneddylation (GO:0000338) | 3.06618356 |
| 73 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.06483676 |
| 74 | retinal ganglion cell axon guidance (GO:0031290) | 3.06229507 |
| 75 | histone H3-K9 demethylation (GO:0033169) | 3.05476225 |
| 76 | neuron fate determination (GO:0048664) | 3.04436872 |
| 77 | neuronal stem cell maintenance (GO:0097150) | 3.02810419 |
| 78 | ribosomal small subunit biogenesis (GO:0042274) | 3.02120696 |
| 79 | S-adenosylmethionine metabolic process (GO:0046500) | 2.99601485 |
| 80 | CTP biosynthetic process (GO:0006241) | 2.99548133 |
| 81 | CTP metabolic process (GO:0046036) | 2.99548133 |
| 82 | detection of external biotic stimulus (GO:0098581) | 2.95303987 |
| 83 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.94315050 |
| 84 | regulation of B cell differentiation (GO:0045577) | 2.93988174 |
| 85 | regulation of granulocyte differentiation (GO:0030852) | 2.92713551 |
| 86 | tolerance induction (GO:0002507) | 2.89384089 |
| 87 | amino acid salvage (GO:0043102) | 2.89360024 |
| 88 | L-methionine salvage (GO:0071267) | 2.89360024 |
| 89 | L-methionine biosynthetic process (GO:0071265) | 2.89360024 |
| 90 | axon ensheathment in central nervous system (GO:0032291) | 2.88220593 |
| 91 | central nervous system myelination (GO:0022010) | 2.88220593 |
| 92 | leukocyte aggregation (GO:0070486) | 2.87805775 |
| 93 | histone H3-K4 trimethylation (GO:0080182) | 2.86963257 |
| 94 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.84625100 |
| 95 | translational termination (GO:0006415) | 2.84507076 |
| 96 | UTP biosynthetic process (GO:0006228) | 2.84260727 |
| 97 | regulation of ARF GTPase activity (GO:0032312) | 2.83452251 |
| 98 | viral transcription (GO:0019083) | 2.82263574 |
| 99 | protein targeting to mitochondrion (GO:0006626) | 2.80367440 |
| 100 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.78366001 |
| 101 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.78366001 |
| 102 | modulation by symbiont of host immune response (GO:0052553) | 2.78366001 |
| 103 | positive regulation by symbiont of host defense response (GO:0052509) | 2.78366001 |
| 104 | modulation by symbiont of host defense response (GO:0052031) | 2.78366001 |
| 105 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.78366001 |
| 106 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.77705992 |
| 107 | negative regulation of B cell mediated immunity (GO:0002713) | 2.77705992 |
| 108 | oligodendrocyte differentiation (GO:0048709) | 2.77646332 |
| 109 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.75577674 |
| 110 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.75085037 |
| 111 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.75085037 |
| 112 | cotranslational protein targeting to membrane (GO:0006613) | 2.74151480 |
| 113 | respiratory chain complex IV assembly (GO:0008535) | 2.73039023 |
| 114 | regulation of tolerance induction (GO:0002643) | 2.72670835 |
| 115 | short-term memory (GO:0007614) | 2.71818269 |
| 116 | cellular extravasation (GO:0045123) | 2.71689931 |
| 117 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.71276101 |
| 118 | chaperone-mediated protein transport (GO:0072321) | 2.70484655 |
| 119 | histone lysine demethylation (GO:0070076) | 2.70426958 |
| 120 | termination of RNA polymerase III transcription (GO:0006386) | 2.68786565 |
| 121 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.68786565 |
| 122 | regulation of necroptotic process (GO:0060544) | 2.68716294 |
| 123 | positive regulation of tolerance induction (GO:0002645) | 2.68040073 |
| 124 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.67735176 |
| 125 | regulation of ARF protein signal transduction (GO:0032012) | 2.67552258 |
| 126 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.67520924 |
| 127 | establishment of viral latency (GO:0019043) | 2.67220124 |
| 128 | establishment of protein localization to mitochondrion (GO:0072655) | 2.67098544 |
| 129 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.66800782 |
| 130 | protein targeting to ER (GO:0045047) | 2.66282226 |
| 131 | UTP metabolic process (GO:0046051) | 2.65301384 |
| 132 | regulation of Rap GTPase activity (GO:0032317) | 2.65132050 |
| 133 | phospholipid scrambling (GO:0017121) | 2.64581376 |
| 134 | GMP metabolic process (GO:0046037) | 2.64567652 |
| 135 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.64002285 |
| 136 | cranial nerve development (GO:0021545) | 2.63810571 |
| 137 | protein-cofactor linkage (GO:0018065) | 2.63488711 |
| 138 | negative regulation of myotube differentiation (GO:0010832) | 2.62922652 |
| 139 | negative regulation of T cell mediated immunity (GO:0002710) | 2.62103166 |
| 140 | positive regulation of neuroblast proliferation (GO:0002052) | 2.61770904 |
| 141 | regulation of apoptotic cell clearance (GO:2000425) | 2.61165871 |
| 142 | T cell migration (GO:0072678) | 2.60938845 |
| 143 | protein neddylation (GO:0045116) | 2.60900360 |
| 144 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.59692991 |
| 145 | epithelial cilium movement (GO:0003351) | 2.59324031 |
| 146 | Peyers patch development (GO:0048541) | 2.58285148 |
| 147 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.58285148 |
| 148 | detection of biotic stimulus (GO:0009595) | 2.58247729 |
| 149 | catecholamine transport (GO:0051937) | 2.57563354 |
| 150 | nonmotile primary cilium assembly (GO:0035058) | 2.57556307 |
| 151 | embryonic forelimb morphogenesis (GO:0035115) | 2.57418333 |
| 152 | histone demethylation (GO:0016577) | 2.55526231 |
| 153 | protein localization to endoplasmic reticulum (GO:0070972) | 2.54379587 |
| 154 | protein localization to mitochondrion (GO:0070585) | 2.53677318 |
| 155 | auditory behavior (GO:0031223) | 2.53141176 |
| 156 | negative regulation of type 2 immune response (GO:0002829) | 2.53009353 |
| 157 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.52820140 |
| 158 | macrophage activation involved in immune response (GO:0002281) | 2.52750421 |
| 159 | positive regulation of synapse assembly (GO:0051965) | 2.51734318 |
| 160 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.51295109 |
| 161 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.51283596 |
| 162 | detection of molecule of bacterial origin (GO:0032490) | 2.51028101 |
| 163 | negative regulation of granulocyte differentiation (GO:0030853) | 2.50736370 |
| 164 | cochlea development (GO:0090102) | 2.50658798 |
| 165 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.49858956 |
| 166 | definitive hemopoiesis (GO:0060216) | 2.49417573 |
| 167 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.49270489 |
| 168 | intracellular protein transmembrane import (GO:0044743) | 2.49006716 |
| 169 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.48820692 |
| 170 | interkinetic nuclear migration (GO:0022027) | 2.48672266 |
| 171 | regulation of mitochondrial translation (GO:0070129) | 2.48047056 |
| 172 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.47216839 |
| 173 | spliceosomal complex assembly (GO:0000245) | 2.45505560 |
| 174 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.45032302 |
| 175 | negative regulation of adaptive immune response (GO:0002820) | 2.44596906 |
| 176 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 2.44003133 |
| 177 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.43907142 |
| 178 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.43764894 |
| 179 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.43502378 |
| 180 | response to type I interferon (GO:0034340) | 2.42908859 |
| 181 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.41539303 |
| 182 | fatty acid elongation (GO:0030497) | 2.40018228 |
| 183 | response to peptidoglycan (GO:0032494) | 2.39950568 |
| 184 | cellular response to ethanol (GO:0071361) | 2.39633314 |
| 185 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.39135953 |
| 186 | DNA ligation (GO:0006266) | 2.38177340 |
| 187 | cellular response to fatty acid (GO:0071398) | 2.38145855 |
| 188 | facial nerve structural organization (GO:0021612) | 2.37996836 |
| 189 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.37957501 |
| 190 | centriole replication (GO:0007099) | 2.37439419 |
| 191 | negative regulation of humoral immune response (GO:0002921) | 2.37151180 |
| 192 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.36850344 |
| 193 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.35179745 |
| 194 | cellular response to type I interferon (GO:0071357) | 2.33601701 |
| 195 | type I interferon signaling pathway (GO:0060337) | 2.33601701 |
| 196 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.32864612 |
| 197 | embryonic process involved in female pregnancy (GO:0060136) | 2.32037492 |
| 198 | histone H4 deacetylation (GO:0070933) | 2.32007131 |
| 199 | activation of JUN kinase activity (GO:0007257) | 2.31137334 |
| 200 | immunoglobulin mediated immune response (GO:0016064) | 2.30588609 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 4.23685029 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.07566336 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.04159467 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.65631470 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.30460494 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.19095983 |
| 7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.18935502 |
| 8 | MYC_22102868_ChIP-Seq_BL_Human | 2.94784712 |
| 9 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.82471402 |
| 10 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.81871500 |
| 11 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.75306541 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.72263352 |
| 13 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.63415953 |
| 14 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.62472228 |
| 15 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.61552573 |
| 16 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.54508821 |
| 17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.49636546 |
| 18 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.49071227 |
| 19 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.42935084 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 2.42336121 |
| 21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.41104757 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.40685383 |
| 23 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.37138774 |
| 24 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.36137737 |
| 25 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.36107236 |
| 26 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.36065974 |
| 27 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.33478111 |
| 28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.32824627 |
| 29 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.29191962 |
| 30 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.26127695 |
| 31 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.25852767 |
| 32 | MAF_26560356_Chip-Seq_TH1_Human | 2.24349887 |
| 33 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.23922611 |
| 34 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.22716768 |
| 35 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.21057138 |
| 36 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.18885462 |
| 37 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.18488740 |
| 38 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.11300978 |
| 39 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.11038574 |
| 40 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.10306727 |
| 41 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.05309945 |
| 42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.03562902 |
| 43 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.02640431 |
| 44 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.01294865 |
| 45 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.97542193 |
| 46 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.94299018 |
| 47 | UTX_26944678_Chip-Seq_JUKART_Human | 1.91477418 |
| 48 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.89785768 |
| 49 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89440797 |
| 50 | EWS_26573619_Chip-Seq_HEK293_Human | 1.89013641 |
| 51 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.88790245 |
| 52 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.88510800 |
| 53 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.87961026 |
| 54 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.87903485 |
| 55 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.86298170 |
| 56 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.84946483 |
| 57 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.84855599 |
| 58 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.82142518 |
| 59 | SPI1_23127762_ChIP-Seq_K562_Human | 1.81561138 |
| 60 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.81204177 |
| 61 | * MYB_26560356_Chip-Seq_TH2_Human | 1.79188599 |
| 62 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.78707124 |
| 63 | MYB_26560356_Chip-Seq_TH1_Human | 1.78051590 |
| 64 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.76816262 |
| 65 | P300_19829295_ChIP-Seq_ESCs_Human | 1.76418169 |
| 66 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.75145344 |
| 67 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.75006534 |
| 68 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.74923865 |
| 69 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.74391216 |
| 70 | MAF_26560356_Chip-Seq_TH2_Human | 1.74193185 |
| 71 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.71974151 |
| 72 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.71523557 |
| 73 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.68421280 |
| 74 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.66780026 |
| 75 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.66024194 |
| 76 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.65682123 |
| 77 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.62802258 |
| 78 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.61697998 |
| 79 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.61668852 |
| 80 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.60715168 |
| 81 | GATA1_19941826_ChIP-Seq_K562_Human | 1.58308030 |
| 82 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.58006056 |
| 83 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.56998308 |
| 84 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.55247647 |
| 85 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.54482164 |
| 86 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.54378236 |
| 87 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.54130123 |
| 88 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.51097995 |
| 89 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.50541686 |
| 90 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.48862253 |
| 91 | KDM2B_26808549_Chip-Seq_K562_Human | 1.48109856 |
| 92 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.44222841 |
| 93 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.44222841 |
| 94 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.44170808 |
| 95 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.43451252 |
| 96 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.42993547 |
| 97 | VDR_22108803_ChIP-Seq_LS180_Human | 1.41617154 |
| 98 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.40294134 |
| 99 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.40175737 |
| 100 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.39494096 |
| 101 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.38967868 |
| 102 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.38934418 |
| 103 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.38389880 |
| 104 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.37654814 |
| 105 | GATA1_22025678_ChIP-Seq_K562_Human | 1.36578241 |
| 106 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.36574929 |
| 107 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.36160361 |
| 108 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.32583757 |
| 109 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.32262903 |
| 110 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.30468587 |
| 111 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.28634645 |
| 112 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.28523115 |
| 113 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.28049670 |
| 114 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.26721104 |
| 115 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.26096162 |
| 116 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.26019439 |
| 117 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.25309091 |
| 118 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.25087504 |
| 119 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.24352413 |
| 120 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23969323 |
| 121 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.22922013 |
| 122 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.21766113 |
| 123 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.21727952 |
| 124 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.21130361 |
| 125 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.20764644 |
| 126 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.19703445 |
| 127 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.19656343 |
| 128 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.19024440 |
| 129 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.18700798 |
| 130 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.18603937 |
| 131 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.18469398 |
| 132 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.17667971 |
| 133 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.17650455 |
| 134 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.17219866 |
| 135 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.17178739 |
| 136 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.15225402 |
| 137 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.14675618 |
| 138 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13877862 |
| 139 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.12957446 |
| 140 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.12260452 |
| 141 | JUN_21703547_ChIP-Seq_K562_Human | 1.11513770 |
| 142 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.10234062 |
| 143 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.09991401 |
| 144 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.09375906 |
| 145 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.09305023 |
| 146 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.09037958 |
| 147 | GATA2_19941826_ChIP-Seq_K562_Human | 1.08626373 |
| 148 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.08532366 |
| 149 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.08163839 |
| 150 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.08044000 |
| 151 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.06971759 |
| 152 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.06621334 |
| 153 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.06551506 |
| 154 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.06270805 |
| 155 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05150561 |
| 156 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.04762501 |
| 157 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04646329 |
| 158 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.04068048 |
| 159 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.03869857 |
| 160 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.03621929 |
| 161 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.03035434 |
| 162 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.02339799 |
| 163 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.02268041 |
| 164 | * GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02221739 |
| 165 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.02189364 |
| 166 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.02159906 |
| 167 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.01035723 |
| 168 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.00573694 |
| 169 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.00382084 |
| 170 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.00252763 |
| 171 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.99965723 |
| 172 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.99781533 |
| 173 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.99696921 |
| 174 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99128630 |
| 175 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.98512544 |
| 176 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.98254315 |
| 177 | * TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.97966564 |
| 178 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.97267092 |
| 179 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.96570053 |
| 180 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.96473960 |
| 181 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.96285335 |
| 182 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.96205131 |
| 183 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.95230952 |
| 184 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.94966094 |
| 185 | P68_20966046_ChIP-Seq_HELA_Human | 0.94756127 |
| 186 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.94656692 |
| 187 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.94452351 |
| 188 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.94297698 |
| 189 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.94074694 |
| 190 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.93854540 |
| 191 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.93088388 |
| 192 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.92561164 |
| 193 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.92251342 |
| 194 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.91804991 |
| 195 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.91790191 |
| 196 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.91780377 |
| 197 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.91523074 |
| 198 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.91059500 |
| 199 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.90995287 |
| 200 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90690522 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010368_abnormal_lymphatic_system | 4.40182633 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.12377843 |
| 3 | MP0003436_decreased_susceptibility_to | 3.41552656 |
| 4 | MP0003880_abnormal_central_pattern | 3.37448708 |
| 5 | MP0003763_abnormal_thymus_physiology | 3.22207688 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.09713272 |
| 7 | MP0003172_abnormal_lysosome_physiology | 3.00215303 |
| 8 | MP0002396_abnormal_hematopoietic_system | 2.98677405 |
| 9 | MP0006276_abnormal_autonomic_nervous | 2.97707422 |
| 10 | MP0000537_abnormal_urethra_morphology | 2.91006503 |
| 11 | MP0009697_abnormal_copulation | 2.87209149 |
| 12 | MP0003303_peritoneal_inflammation | 2.84367383 |
| 13 | MP0002102_abnormal_ear_morphology | 2.71630381 |
| 14 | MP0001800_abnormal_humoral_immune | 2.70268734 |
| 15 | MP0000685_abnormal_immune_system | 2.67206000 |
| 16 | MP0005387_immune_system_phenotype | 2.57561596 |
| 17 | MP0001790_abnormal_immune_system | 2.57561596 |
| 18 | MP0003315_abnormal_perineum_morphology | 2.40100105 |
| 19 | MP0001879_abnormal_lymphatic_vessel | 2.32552668 |
| 20 | MP0003136_yellow_coat_color | 2.28747461 |
| 21 | MP0003724_increased_susceptibility_to | 2.27760268 |
| 22 | MP0006292_abnormal_olfactory_placode | 2.27251086 |
| 23 | MP0003300_gastrointestinal_ulcer | 2.26807879 |
| 24 | MP0004147_increased_porphyrin_level | 2.25570981 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 2.24954081 |
| 26 | MP0001529_abnormal_vocalization | 2.23909409 |
| 27 | MP0002132_abnormal_respiratory_system | 2.22581994 |
| 28 | MP0005025_abnormal_response_to | 2.19148579 |
| 29 | MP0005000_abnormal_immune_tolerance | 2.16969009 |
| 30 | MP0002419_abnormal_innate_immunity | 2.14744157 |
| 31 | MP0000778_abnormal_nervous_system | 2.12442290 |
| 32 | MP0002723_abnormal_immune_serum | 2.11941261 |
| 33 | MP0003122_maternal_imprinting | 2.11462560 |
| 34 | MP0001905_abnormal_dopamine_level | 2.08687047 |
| 35 | MP0002420_abnormal_adaptive_immunity | 2.08580948 |
| 36 | MP0005076_abnormal_cell_differentiation | 2.07605465 |
| 37 | MP0005671_abnormal_response_to | 2.05519077 |
| 38 | MP0001819_abnormal_immune_cell | 2.05064699 |
| 39 | MP0002452_abnormal_antigen_presenting | 1.98843806 |
| 40 | MP0010155_abnormal_intestine_physiology | 1.97086968 |
| 41 | MP0002938_white_spotting | 1.89808104 |
| 42 | MP0002405_respiratory_system_inflammati | 1.88820101 |
| 43 | MP0002398_abnormal_bone_marrow | 1.87025665 |
| 44 | MP0005187_abnormal_penis_morphology | 1.83627465 |
| 45 | MP0004133_heterotaxia | 1.82604102 |
| 46 | MP0002166_altered_tumor_susceptibility | 1.82143287 |
| 47 | MP0009250_abnormal_appendicular_skeleto | 1.80179633 |
| 48 | MP0009278_abnormal_bone_marrow | 1.76839046 |
| 49 | MP0005058_abnormal_lysosome_morphology | 1.75958411 |
| 50 | MP0005451_abnormal_body_composition | 1.75259635 |
| 51 | MP0002736_abnormal_nociception_after | 1.74783852 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.74759311 |
| 53 | MP0000716_abnormal_immune_system | 1.73371748 |
| 54 | MP0003690_abnormal_glial_cell | 1.71214005 |
| 55 | MP0005408_hypopigmentation | 1.70346372 |
| 56 | MP0004808_abnormal_hematopoietic_stem | 1.64671613 |
| 57 | MP0000703_abnormal_thymus_morphology | 1.63517716 |
| 58 | MP0004947_skin_inflammation | 1.62654596 |
| 59 | MP0002933_joint_inflammation | 1.61123743 |
| 60 | MP0002139_abnormal_hepatobiliary_system | 1.61108240 |
| 61 | MP0005423_abnormal_somatic_nervous | 1.59603578 |
| 62 | MP0002751_abnormal_autonomic_nervous | 1.58546098 |
| 63 | MP0005464_abnormal_platelet_physiology | 1.58394108 |
| 64 | MP0000631_abnormal_neuroendocrine_gland | 1.57716918 |
| 65 | MP0003866_abnormal_defecation | 1.54771373 |
| 66 | MP0008789_abnormal_olfactory_epithelium | 1.48114008 |
| 67 | MP0009785_altered_susceptibility_to | 1.47290672 |
| 68 | MP0002722_abnormal_immune_system | 1.47198784 |
| 69 | MP0003183_abnormal_peptide_metabolism | 1.47094292 |
| 70 | MP0004270_analgesia | 1.45822443 |
| 71 | MP0000049_abnormal_middle_ear | 1.44725104 |
| 72 | MP0001299_abnormal_eye_distance/ | 1.44368974 |
| 73 | MP0001533_abnormal_skeleton_physiology | 1.43883174 |
| 74 | MP0000689_abnormal_spleen_morphology | 1.43421409 |
| 75 | MP0002249_abnormal_larynx_morphology | 1.41149690 |
| 76 | MP0008260_abnormal_autophagy | 1.40702868 |
| 77 | MP0001851_eye_inflammation | 1.39735659 |
| 78 | MP0001873_stomach_inflammation | 1.39446866 |
| 79 | MP0005666_abnormal_adipose_tissue | 1.38829235 |
| 80 | MP0003121_genomic_imprinting | 1.38523791 |
| 81 | MP0001188_hyperpigmentation | 1.37135578 |
| 82 | MP0002429_abnormal_blood_cell | 1.36222407 |
| 83 | MP0001984_abnormal_olfaction | 1.36132317 |
| 84 | MP0003191_abnormal_cellular_cholesterol | 1.35871378 |
| 85 | MP0001545_abnormal_hematopoietic_system | 1.35393735 |
| 86 | MP0005397_hematopoietic_system_phenotyp | 1.35393735 |
| 87 | MP0001270_distended_abdomen | 1.33768895 |
| 88 | MP0002735_abnormal_chemical_nociception | 1.32238384 |
| 89 | MP0000858_altered_metastatic_potential | 1.29860818 |
| 90 | MP0002998_abnormal_bone_remodeling | 1.29722993 |
| 91 | MP0009333_abnormal_splenocyte_physiolog | 1.29169398 |
| 92 | MP0002233_abnormal_nose_morphology | 1.28803502 |
| 93 | MP0003705_abnormal_hypodermis_morpholog | 1.28063249 |
| 94 | MP0002184_abnormal_innervation | 1.27334907 |
| 95 | MP0008932_abnormal_embryonic_tissue | 1.26741962 |
| 96 | MP0006082_CNS_inflammation | 1.26573740 |
| 97 | MP0003938_abnormal_ear_development | 1.26528542 |
| 98 | MP0003091_abnormal_cell_migration | 1.24481762 |
| 99 | MP0000372_irregular_coat_pigmentation | 1.23538051 |
| 100 | MP0003755_abnormal_palate_morphology | 1.21639343 |
| 101 | MP0003942_abnormal_urinary_system | 1.20377909 |
| 102 | MP0001845_abnormal_inflammatory_respons | 1.19651581 |
| 103 | MP0002009_preneoplasia | 1.19460759 |
| 104 | MP0001958_emphysema | 1.19435907 |
| 105 | MP0005360_urolithiasis | 1.19019352 |
| 106 | MP0009115_abnormal_fat_cell | 1.17782536 |
| 107 | MP0005365_abnormal_bile_salt | 1.16992174 |
| 108 | MP0003828_pulmonary_edema | 1.16920299 |
| 109 | MP0003868_abnormal_feces_composition | 1.16457746 |
| 110 | MP0004130_abnormal_muscle_cell | 1.16027140 |
| 111 | MP0002734_abnormal_mechanical_nocicepti | 1.15609507 |
| 112 | MP0004145_abnormal_muscle_electrophysio | 1.15586465 |
| 113 | MP0005646_abnormal_pituitary_gland | 1.13432751 |
| 114 | MP0001849_ear_inflammation | 1.09727568 |
| 115 | MP0003656_abnormal_erythrocyte_physiolo | 1.09670372 |
| 116 | MP0004883_abnormal_blood_vessel | 1.07593999 |
| 117 | MP0005171_absent_coat_pigmentation | 1.05433465 |
| 118 | MP0004142_abnormal_muscle_tone | 1.05267810 |
| 119 | MP0002177_abnormal_outer_ear | 1.04950770 |
| 120 | MP0004185_abnormal_adipocyte_glucose | 1.04673870 |
| 121 | MP0000026_abnormal_inner_ear | 1.01296559 |
| 122 | MP0003890_abnormal_embryonic-extraembry | 1.01050835 |
| 123 | MP0009384_cardiac_valve_regurgitation | 1.00985612 |
| 124 | MP0003385_abnormal_body_wall | 1.00724527 |
| 125 | MP0002876_abnormal_thyroid_physiology | 0.99503199 |
| 126 | MP0005220_abnormal_exocrine_pancreas | 0.97913094 |
| 127 | MP0001853_heart_inflammation | 0.97291380 |
| 128 | MP0003279_aneurysm | 0.97092608 |
| 129 | MP0003861_abnormal_nervous_system | 0.96796270 |
| 130 | MP0003937_abnormal_limbs/digits/tail_de | 0.96588782 |
| 131 | MP0004885_abnormal_endolymph | 0.96053505 |
| 132 | MP0005085_abnormal_gallbladder_physiolo | 0.95387074 |
| 133 | MP0002127_abnormal_cardiovascular_syste | 0.95363708 |
| 134 | MP0008469_abnormal_protein_level | 0.95243513 |
| 135 | MP0002971_abnormal_brown_adipose | 0.95032424 |
| 136 | MP0000955_abnormal_spinal_cord | 0.95017413 |
| 137 | MP0002272_abnormal_nervous_system | 0.93529031 |
| 138 | MP0005375_adipose_tissue_phenotype | 0.92882804 |
| 139 | MP0002163_abnormal_gland_morphology | 0.92505282 |
| 140 | MP0002067_abnormal_sensory_capabilities | 0.92407216 |
| 141 | MP0005310_abnormal_salivary_gland | 0.92073598 |
| 142 | MP0005409_darkened_coat_color | 0.89230385 |
| 143 | MP0005394_taste/olfaction_phenotype | 0.89074564 |
| 144 | MP0005499_abnormal_olfactory_system | 0.89074564 |
| 145 | MP0000249_abnormal_blood_vessel | 0.88882866 |
| 146 | MP0002063_abnormal_learning/memory/cond | 0.88841151 |
| 147 | MP0009053_abnormal_anal_canal | 0.88704451 |
| 148 | MP0003635_abnormal_synaptic_transmissio | 0.87979243 |
| 149 | MP0004381_abnormal_hair_follicle | 0.87529044 |
| 150 | MP0002557_abnormal_social/conspecific_i | 0.87499430 |
| 151 | MP0005164_abnormal_response_to | 0.86752583 |
| 152 | MP0000465_gastrointestinal_hemorrhage | 0.84594041 |
| 153 | MP0001340_abnormal_eyelid_morphology | 0.84331306 |
| 154 | MP0002006_tumorigenesis | 0.83981754 |
| 155 | MP0002282_abnormal_trachea_morphology | 0.83765469 |
| 156 | MP0002733_abnormal_thermal_nociception | 0.81246707 |
| 157 | MP0002148_abnormal_hypersensitivity_rea | 0.81196189 |
| 158 | MP0002752_abnormal_somatic_nervous | 0.80309413 |
| 159 | MP0003718_maternal_effect | 0.79095070 |
| 160 | MP0001440_abnormal_grooming_behavior | 0.78653476 |
| 161 | MP0002572_abnormal_emotion/affect_behav | 0.78468073 |
| 162 | MP0009745_abnormal_behavioral_response | 0.78270881 |
| 163 | MP0008961_abnormal_basal_metabolism | 0.77569379 |
| 164 | MP0002152_abnormal_brain_morphology | 0.77502542 |
| 165 | MP0001663_abnormal_digestive_system | 0.76378123 |
| 166 | MP0001286_abnormal_eye_development | 0.74923750 |
| 167 | MP0006035_abnormal_mitochondrial_morpho | 0.74532978 |
| 168 | MP0003567_abnormal_fetal_cardiomyocyte | 0.74475966 |
| 169 | MP0003195_calcinosis | 0.74107283 |
| 170 | MP0010329_abnormal_lipoprotein_level | 0.73860611 |
| 171 | MP0006072_abnormal_retinal_apoptosis | 0.73609778 |
| 172 | MP0001485_abnormal_pinna_reflex | 0.73130693 |
| 173 | MP0004215_abnormal_myocardial_fiber | 0.72032973 |
| 174 | MP0001486_abnormal_startle_reflex | 0.72032109 |
| 175 | MP0001970_abnormal_pain_threshold | 0.71454450 |
| 176 | MP0002064_seizures | 0.70914315 |
| 177 | MP0001915_intracranial_hemorrhage | 0.70436570 |
| 178 | MP0002638_abnormal_pupillary_reflex | 0.69744083 |
| 179 | MP0004264_abnormal_extraembryonic_tissu | 0.69209223 |
| 180 | MP0008057_abnormal_DNA_replication | 0.68350030 |
| 181 | MP0008995_early_reproductive_senescence | 0.68304699 |
| 182 | MP0003045_fibrosis | 0.68240273 |
| 183 | MP0005388_respiratory_system_phenotype | 0.68037369 |
| 184 | MP0002133_abnormal_respiratory_system | 0.68037369 |
| 185 | MP0000609_abnormal_liver_physiology | 0.67194906 |
| 186 | MP0002882_abnormal_neuron_morphology | 0.66414767 |
| 187 | MP0008875_abnormal_xenobiotic_pharmacok | 0.66003589 |
| 188 | MP0005503_abnormal_tendon_morphology | 0.65520090 |
| 189 | MP0001986_abnormal_taste_sensitivity | 0.64210202 |
| 190 | MP0003453_abnormal_keratinocyte_physiol | 0.62799701 |
| 191 | MP0001348_abnormal_lacrimal_gland | 0.62520061 |
| 192 | MP0005390_skeleton_phenotype | 0.61021297 |
| 193 | MP0005621_abnormal_cell_physiology | 0.60451078 |
| 194 | MP0009763_increased_sensitivity_to | 0.59654483 |
| 195 | MP0003795_abnormal_bone_structure | 0.58848506 |
| 196 | MP0000767_abnormal_smooth_muscle | 0.58824610 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | High anterior hairline (HP:0009890) | 4.97319978 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.37860293 |
| 3 | Abnormality of the columella (HP:0009929) | 4.35380213 |
| 4 | Eczematoid dermatitis (HP:0000976) | 4.02546711 |
| 5 | Supernumerary spleens (HP:0009799) | 3.84977747 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.80624369 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.79224800 |
| 8 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 3.76585922 |
| 9 | Acute encephalopathy (HP:0006846) | 3.64706705 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.54955723 |
| 11 | Colitis (HP:0002583) | 3.45695432 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.37368235 |
| 13 | Abnormality of the fingertips (HP:0001211) | 3.26027536 |
| 14 | Median cleft lip (HP:0000161) | 3.20263269 |
| 15 | Abnormality of the frontal sinuses (HP:0002687) | 3.19117468 |
| 16 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 3.18528078 |
| 17 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.05400693 |
| 18 | Panhypogammaglobulinemia (HP:0003139) | 3.03992996 |
| 19 | Nasal polyposis (HP:0100582) | 2.97748643 |
| 20 | Increased CSF lactate (HP:0002490) | 2.95827277 |
| 21 | Myositis (HP:0100614) | 2.95622237 |
| 22 | Retinal dysplasia (HP:0007973) | 2.93257991 |
| 23 | Papilledema (HP:0001085) | 2.91700394 |
| 24 | Gastrointestinal inflammation (HP:0004386) | 2.90223731 |
| 25 | Gastrointestinal infarctions (HP:0005244) | 2.89801186 |
| 26 | Agammaglobulinemia (HP:0004432) | 2.89227679 |
| 27 | Recurrent sinusitis (HP:0011108) | 2.88774665 |
| 28 | Increased hepatocellular lipid droplets (HP:0006565) | 2.87474679 |
| 29 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.86861831 |
| 30 | Inflammation of the large intestine (HP:0002037) | 2.85009823 |
| 31 | Gait imbalance (HP:0002141) | 2.81473316 |
| 32 | Recurrent bacterial skin infections (HP:0005406) | 2.79960483 |
| 33 | Obstructive sleep apnea (HP:0002870) | 2.77937928 |
| 34 | Recurrent fungal infections (HP:0002841) | 2.75184477 |
| 35 | Chronic otitis media (HP:0000389) | 2.74541382 |
| 36 | Prolonged bleeding time (HP:0003010) | 2.74321842 |
| 37 | Increased IgE level (HP:0003212) | 2.74033424 |
| 38 | Meningitis (HP:0001287) | 2.73985089 |
| 39 | Recurrent abscess formation (HP:0002722) | 2.71097228 |
| 40 | Recurrent bronchitis (HP:0002837) | 2.71014180 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.70019871 |
| 42 | Lipid accumulation in hepatocytes (HP:0006561) | 2.69302951 |
| 43 | Cerebral edema (HP:0002181) | 2.67270354 |
| 44 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.66783508 |
| 45 | Renal Fanconi syndrome (HP:0001994) | 2.66292063 |
| 46 | Congenital primary aphakia (HP:0007707) | 2.62948348 |
| 47 | Hypothermia (HP:0002045) | 2.60804028 |
| 48 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.57982666 |
| 49 | Deep venous thrombosis (HP:0002625) | 2.56148297 |
| 50 | Abnormality of glycolysis (HP:0004366) | 2.56129109 |
| 51 | Increased serum pyruvate (HP:0003542) | 2.56129109 |
| 52 | Abnormality of the nasal mucosa (HP:0000433) | 2.54418498 |
| 53 | Spontaneous hematomas (HP:0007420) | 2.52631285 |
| 54 | Hepatic necrosis (HP:0002605) | 2.52114739 |
| 55 | Asplenia (HP:0001746) | 2.51868090 |
| 56 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.50316815 |
| 57 | Recurrent cutaneous fungal infections (HP:0011370) | 2.50316815 |
| 58 | Recurrent viral infections (HP:0004429) | 2.49687891 |
| 59 | Optic disc pallor (HP:0000543) | 2.49373867 |
| 60 | Gingivitis (HP:0000230) | 2.48815775 |
| 61 | Vasculitis (HP:0002633) | 2.48294289 |
| 62 | Hyperventilation (HP:0002883) | 2.47528877 |
| 63 | Abnormality of the axillary hair (HP:0100134) | 2.45796822 |
| 64 | Abnormality of secondary sexual hair (HP:0009888) | 2.45796822 |
| 65 | Cellulitis (HP:0100658) | 2.44736813 |
| 66 | Gastrointestinal stroma tumor (HP:0100723) | 2.38543729 |
| 67 | Mediastinal lymphadenopathy (HP:0100721) | 2.35511297 |
| 68 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.34972411 |
| 69 | 3-Methylglutaconic aciduria (HP:0003535) | 2.34449542 |
| 70 | Poor suck (HP:0002033) | 2.33156391 |
| 71 | Recurrent skin infections (HP:0001581) | 2.32665906 |
| 72 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.32379213 |
| 73 | Bronchiectasis (HP:0002110) | 2.32204965 |
| 74 | Cerebral aneurysm (HP:0004944) | 2.32091571 |
| 75 | Broad palm (HP:0001169) | 2.29852969 |
| 76 | Abnormal ciliary motility (HP:0012262) | 2.29440231 |
| 77 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.27340990 |
| 78 | Nephrogenic diabetes insipidus (HP:0009806) | 2.26666814 |
| 79 | Abnormality of the incisor (HP:0000676) | 2.26466049 |
| 80 | Flat acetabular roof (HP:0003180) | 2.26037127 |
| 81 | Orchitis (HP:0100796) | 2.25302227 |
| 82 | Complement deficiency (HP:0004431) | 2.25123491 |
| 83 | Viral hepatitis (HP:0006562) | 2.24221640 |
| 84 | Abnormality of the peritoneum (HP:0002585) | 2.23223558 |
| 85 | Glomerulonephritis (HP:0000099) | 2.22954123 |
| 86 | Emphysema (HP:0002097) | 2.22286184 |
| 87 | Hypoplastic heart (HP:0001961) | 2.21765436 |
| 88 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.20869993 |
| 89 | Single umbilical artery (HP:0001195) | 2.20869993 |
| 90 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.20869993 |
| 91 | Hemorrhage of the eye (HP:0011885) | 2.20818149 |
| 92 | Recurrent otitis media (HP:0000403) | 2.20094209 |
| 93 | Limb dystonia (HP:0002451) | 2.19722737 |
| 94 | Pustule (HP:0200039) | 2.18082753 |
| 95 | Epistaxis (HP:0000421) | 2.17393613 |
| 96 | Metaphyseal cupping (HP:0003021) | 2.16639881 |
| 97 | Optic neuritis (HP:0100653) | 2.15947175 |
| 98 | Retrobulbar optic neuritis (HP:0100654) | 2.15947175 |
| 99 | True hermaphroditism (HP:0010459) | 2.15099020 |
| 100 | Lissencephaly (HP:0001339) | 2.14972945 |
| 101 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.13560514 |
| 102 | Fair hair (HP:0002286) | 2.11896737 |
| 103 | Chronic hepatic failure (HP:0100626) | 2.11230267 |
| 104 | Occipital encephalocele (HP:0002085) | 2.10888300 |
| 105 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.10270751 |
| 106 | Bronchitis (HP:0012387) | 2.10108107 |
| 107 | Leukodystrophy (HP:0002415) | 2.10064462 |
| 108 | Pulmonary embolism (HP:0002204) | 2.08320116 |
| 109 | Amniotic constriction ring (HP:0009775) | 2.08145618 |
| 110 | Abnormality of placental membranes (HP:0011409) | 2.08145618 |
| 111 | T lymphocytopenia (HP:0005403) | 2.07844450 |
| 112 | Gingival bleeding (HP:0000225) | 2.06739539 |
| 113 | Chronic obstructive pulmonary disease (HP:0006510) | 2.06463088 |
| 114 | Obstructive lung disease (HP:0006536) | 2.06463088 |
| 115 | Hypoplastic left heart (HP:0004383) | 2.05974832 |
| 116 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.05894049 |
| 117 | Abnormality of macrophages (HP:0004311) | 2.04112845 |
| 118 | Broad face (HP:0000283) | 2.03779385 |
| 119 | Rimmed vacuoles (HP:0003805) | 2.02167158 |
| 120 | Exercise intolerance (HP:0003546) | 2.01465592 |
| 121 | Multiple lipomas (HP:0001012) | 2.00672144 |
| 122 | Aplasia of the musculature (HP:0100854) | 1.99770488 |
| 123 | Systemic lupus erythematosus (HP:0002725) | 1.99701924 |
| 124 | Absent/shortened dynein arms (HP:0200106) | 1.99371349 |
| 125 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.99371349 |
| 126 | Vaginal atresia (HP:0000148) | 1.99338630 |
| 127 | Dislocated radial head (HP:0003083) | 1.98812579 |
| 128 | Genital tract atresia (HP:0001827) | 1.98245738 |
| 129 | Enlarged kidneys (HP:0000105) | 1.97738943 |
| 130 | Encephalitis (HP:0002383) | 1.97142223 |
| 131 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.96983823 |
| 132 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.95972942 |
| 133 | Abnormality of complement system (HP:0005339) | 1.95712685 |
| 134 | Lactic acidosis (HP:0003128) | 1.94291237 |
| 135 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.93787067 |
| 136 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.93787067 |
| 137 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.93567508 |
| 138 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.93567508 |
| 139 | Diastasis recti (HP:0001540) | 1.93044861 |
| 140 | Pulmonary infiltrates (HP:0002113) | 1.93024687 |
| 141 | Respiratory failure (HP:0002878) | 1.92976881 |
| 142 | Abnormal pupillary function (HP:0007686) | 1.92291896 |
| 143 | Abnormality of T cell number (HP:0011839) | 1.90706035 |
| 144 | X-linked dominant inheritance (HP:0001423) | 1.90234888 |
| 145 | Fatigue (HP:0012378) | 1.89678531 |
| 146 | Chest pain (HP:0100749) | 1.88633587 |
| 147 | Pancreatic fibrosis (HP:0100732) | 1.88460010 |
| 148 | Peritonitis (HP:0002586) | 1.88419771 |
| 149 | Abnormality of the radial head (HP:0003995) | 1.87707661 |
| 150 | Pancreatic cysts (HP:0001737) | 1.86976009 |
| 151 | Thin bony cortex (HP:0002753) | 1.85216613 |
| 152 | Aortic aneurysm (HP:0004942) | 1.84479837 |
| 153 | Rhinitis (HP:0012384) | 1.84328632 |
| 154 | Microvesicular hepatic steatosis (HP:0001414) | 1.83827857 |
| 155 | Polygenic inheritance (HP:0010982) | 1.83797110 |
| 156 | Restrictive lung disease (HP:0002091) | 1.83464298 |
| 157 | Methylmalonic acidemia (HP:0002912) | 1.83359254 |
| 158 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.81387056 |
| 159 | Aneurysm (HP:0002617) | 1.80964597 |
| 160 | Slow saccadic eye movements (HP:0000514) | 1.80850466 |
| 161 | Arterial tortuosity (HP:0005116) | 1.80415667 |
| 162 | Type II lissencephaly (HP:0007260) | 1.79955912 |
| 163 | Progressive cerebellar ataxia (HP:0002073) | 1.79630560 |
| 164 | Chronic sinusitis (HP:0011109) | 1.78765066 |
| 165 | Fibular hypoplasia (HP:0003038) | 1.77614395 |
| 166 | Type 2 muscle fiber atrophy (HP:0003554) | 1.77393046 |
| 167 | Dysostosis multiplex (HP:0000943) | 1.77332676 |
| 168 | Hemoptysis (HP:0002105) | 1.76450331 |
| 169 | Increased serum lactate (HP:0002151) | 1.76277980 |
| 170 | Humeroradial synostosis (HP:0003041) | 1.76022075 |
| 171 | Synostosis involving the elbow (HP:0003938) | 1.76022075 |
| 172 | Interstitial pulmonary disease (HP:0006530) | 1.75930756 |
| 173 | Increased intramyocellular lipid droplets (HP:0012240) | 1.74912628 |
| 174 | Mucopolysacchariduria (HP:0008155) | 1.74862371 |
| 175 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.74862371 |
| 176 | Granulocytopenia (HP:0001913) | 1.74146793 |
| 177 | Arterial thrombosis (HP:0004420) | 1.73779024 |
| 178 | Postaxial hand polydactyly (HP:0001162) | 1.73775601 |
| 179 | Postnatal microcephaly (HP:0005484) | 1.73759718 |
| 180 | Methylmalonic aciduria (HP:0012120) | 1.73273919 |
| 181 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.70513038 |
| 182 | Poor coordination (HP:0002370) | 1.69783594 |
| 183 | Spinal cord lesions (HP:0100561) | 1.69759291 |
| 184 | Syringomyelia (HP:0003396) | 1.69759291 |
| 185 | Hypochromic anemia (HP:0001931) | 1.69183400 |
| 186 | Osteomyelitis (HP:0002754) | 1.68931909 |
| 187 | Cupped ribs (HP:0000887) | 1.68799563 |
| 188 | Sclerocornea (HP:0000647) | 1.67772621 |
| 189 | Exertional dyspnea (HP:0002875) | 1.66788978 |
| 190 | Hydroureter (HP:0000072) | 1.66609102 |
| 191 | Congenital, generalized hypertrichosis (HP:0004540) | 1.66550171 |
| 192 | Anomalous pulmonary venous return (HP:0010772) | 1.64729054 |
| 193 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.64596585 |
| 194 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.64596585 |
| 195 | Macrocytic anemia (HP:0001972) | 1.64374738 |
| 196 | Lethargy (HP:0001254) | 1.64016390 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIB3 | 3.17469137 |
| 2 | CASK | 3.15281968 |
| 3 | STK16 | 3.13714673 |
| 4 | RIPK4 | 3.04195455 |
| 5 | MAP4K1 | 2.95425237 |
| 6 | PRPF4B | 2.77005339 |
| 7 | MARK1 | 2.69394828 |
| 8 | MAP3K13 | 2.67303161 |
| 9 | MAP3K12 | 2.61171424 |
| 10 | BMPR1B | 2.45867919 |
| 11 | ERN1 | 2.44582790 |
| 12 | FGFR4 | 2.43569864 |
| 13 | EPHB2 | 2.41759781 |
| 14 | TNIK | 2.37493714 |
| 15 | PNCK | 2.34451967 |
| 16 | SRPK1 | 2.33400920 |
| 17 | TYK2 | 2.32659917 |
| 18 | TIE1 | 2.30165788 |
| 19 | CSNK1G3 | 2.27041466 |
| 20 | BLK | 2.25969740 |
| 21 | STK39 | 2.04351119 |
| 22 | FGFR3 | 2.03267272 |
| 23 | MUSK | 1.94189647 |
| 24 | MKNK1 | 1.91703586 |
| 25 | UHMK1 | 1.91283692 |
| 26 | MKNK2 | 1.89918330 |
| 27 | MAP3K7 | 1.87291412 |
| 28 | BCR | 1.81631880 |
| 29 | NTRK3 | 1.81153323 |
| 30 | MAP3K10 | 1.79562416 |
| 31 | DYRK2 | 1.75806177 |
| 32 | CDK12 | 1.73881525 |
| 33 | SIK2 | 1.71106240 |
| 34 | MAP2K3 | 1.68578569 |
| 35 | BUB1 | 1.67640312 |
| 36 | MAP3K14 | 1.66905845 |
| 37 | CSNK1G2 | 1.65840546 |
| 38 | MAPK15 | 1.65206632 |
| 39 | ZAP70 | 1.64284679 |
| 40 | MAPK13 | 1.63556755 |
| 41 | TGFBR1 | 1.63366040 |
| 42 | LIMK1 | 1.61230185 |
| 43 | RIPK1 | 1.61139055 |
| 44 | CSNK1G1 | 1.60786582 |
| 45 | IRAK2 | 1.59353706 |
| 46 | MARK2 | 1.57209601 |
| 47 | YES1 | 1.57089568 |
| 48 | CSNK1A1L | 1.56866341 |
| 49 | NME2 | 1.53386873 |
| 50 | MAP2K7 | 1.51026244 |
| 51 | BTK | 1.50798570 |
| 52 | TNK2 | 1.50377419 |
| 53 | EEF2K | 1.49800470 |
| 54 | CSK | 1.46580318 |
| 55 | TAOK2 | 1.46183326 |
| 56 | JAK1 | 1.41000811 |
| 57 | JAK3 | 1.40987222 |
| 58 | SIK1 | 1.39471542 |
| 59 | PKN2 | 1.38254270 |
| 60 | VRK1 | 1.32039809 |
| 61 | CDC42BPA | 1.30438151 |
| 62 | ITK | 1.30362186 |
| 63 | CAMKK2 | 1.29095872 |
| 64 | PLK4 | 1.26386139 |
| 65 | NTRK2 | 1.25168176 |
| 66 | OXSR1 | 1.24506490 |
| 67 | ERBB3 | 1.23585649 |
| 68 | SYK | 1.22157382 |
| 69 | BRD4 | 1.21998765 |
| 70 | TBK1 | 1.19250254 |
| 71 | CLK1 | 1.17487961 |
| 72 | TYRO3 | 1.16570513 |
| 73 | ACVR1B | 1.13078055 |
| 74 | MAPK7 | 1.12770431 |
| 75 | MINK1 | 1.09278456 |
| 76 | CSF1R | 1.08669969 |
| 77 | IKBKE | 1.08378880 |
| 78 | ICK | 1.08344865 |
| 79 | HCK | 1.07107027 |
| 80 | KIT | 1.06744642 |
| 81 | FER | 1.06706405 |
| 82 | MYLK | 1.04850382 |
| 83 | MAPK12 | 1.04590996 |
| 84 | CDK19 | 1.04321054 |
| 85 | KSR2 | 1.03989205 |
| 86 | RET | 1.03643289 |
| 87 | GRK6 | 1.03390625 |
| 88 | CAMKK1 | 1.01727894 |
| 89 | GRK1 | 1.00933438 |
| 90 | IRAK4 | 0.98527264 |
| 91 | MAP3K2 | 0.98388578 |
| 92 | HIPK2 | 0.98070855 |
| 93 | MAP3K6 | 0.97030811 |
| 94 | KSR1 | 0.96892746 |
| 95 | TESK2 | 0.96201783 |
| 96 | PTK6 | 0.95997329 |
| 97 | NLK | 0.95270667 |
| 98 | NME1 | 0.94020025 |
| 99 | SMG1 | 0.93393169 |
| 100 | PDGFRA | 0.92000374 |
| 101 | TXK | 0.90294740 |
| 102 | TEC | 0.89034631 |
| 103 | JAK2 | 0.88911335 |
| 104 | IRAK1 | 0.87411049 |
| 105 | LCK | 0.86934093 |
| 106 | PDK1 | 0.86642841 |
| 107 | SIK3 | 0.85707311 |
| 108 | WNK4 | 0.85384993 |
| 109 | GRK7 | 0.85037043 |
| 110 | PLK2 | 0.82342904 |
| 111 | PDPK1 | 0.82293102 |
| 112 | TAOK3 | 0.82090542 |
| 113 | LYN | 0.81765432 |
| 114 | EPHB1 | 0.79709067 |
| 115 | MAPK11 | 0.79519448 |
| 116 | WEE1 | 0.79002486 |
| 117 | PDGFRB | 0.78747752 |
| 118 | BRAF | 0.78471625 |
| 119 | MAP2K6 | 0.78151200 |
| 120 | CDK4 | 0.77609427 |
| 121 | CDK6 | 0.77496503 |
| 122 | FGFR2 | 0.77450859 |
| 123 | BCKDK | 0.77441036 |
| 124 | CAMK2A | 0.76650345 |
| 125 | NEK9 | 0.76142950 |
| 126 | CDK8 | 0.75743030 |
| 127 | FGR | 0.75277418 |
| 128 | TRPM7 | 0.74292358 |
| 129 | MAP3K1 | 0.73567841 |
| 130 | WNK1 | 0.72990751 |
| 131 | PBK | 0.72193185 |
| 132 | CAMK2B | 0.69430133 |
| 133 | PRKD2 | 0.67479496 |
| 134 | AURKA | 0.65181105 |
| 135 | EIF2AK3 | 0.64055446 |
| 136 | MARK3 | 0.62866224 |
| 137 | AKT3 | 0.62294728 |
| 138 | CAMK2D | 0.62234322 |
| 139 | SGK3 | 0.61264373 |
| 140 | ADRBK1 | 0.61001331 |
| 141 | CAMK2G | 0.60185713 |
| 142 | DYRK1B | 0.59409366 |
| 143 | FES | 0.57780694 |
| 144 | LRRK2 | 0.55813242 |
| 145 | RPS6KL1 | 0.55600325 |
| 146 | RPS6KC1 | 0.55600325 |
| 147 | ZAK | 0.55226460 |
| 148 | MTOR | 0.55093367 |
| 149 | SGK2 | 0.55008033 |
| 150 | MAPKAPK5 | 0.53955885 |
| 151 | WNK3 | 0.53702097 |
| 152 | PLK3 | 0.51718552 |
| 153 | PRKCQ | 0.50972759 |
| 154 | FYN | 0.50065644 |
| 155 | EPHA3 | 0.48716853 |
| 156 | MELK | 0.48009604 |
| 157 | ROCK2 | 0.47859514 |
| 158 | OBSCN | 0.47384510 |
| 159 | STK24 | 0.46679577 |
| 160 | PRKAA2 | 0.46154558 |
| 161 | STK11 | 0.45872212 |
| 162 | EPHA4 | 0.45614201 |
| 163 | MAP2K2 | 0.45213054 |
| 164 | PASK | 0.44862844 |
| 165 | MAP2K4 | 0.44403500 |
| 166 | PRKCH | 0.44136111 |
| 167 | CAMK1 | 0.43956434 |
| 168 | DYRK1A | 0.43465320 |
| 169 | RPS6KA6 | 0.43423747 |
| 170 | DYRK3 | 0.42205096 |
| 171 | ABL2 | 0.42118367 |
| 172 | CDK7 | 0.42019101 |
| 173 | ERBB2 | 0.41959909 |
| 174 | CSNK2A2 | 0.41785072 |
| 175 | PINK1 | 0.41643278 |
| 176 | IKBKB | 0.41601676 |
| 177 | ADRBK2 | 0.40531037 |
| 178 | CSNK2A1 | 0.38813137 |
| 179 | PAK3 | 0.38535249 |
| 180 | EIF2AK1 | 0.37940359 |
| 181 | CDK14 | 0.36469533 |
| 182 | CAMK4 | 0.35715217 |
| 183 | RPS6KB1 | 0.34586178 |
| 184 | AURKB | 0.33717027 |
| 185 | CDK5 | 0.33673103 |
| 186 | FRK | 0.33109795 |
| 187 | INSRR | 0.32095345 |
| 188 | TLK1 | 0.31719653 |
| 189 | GRK5 | 0.31382278 |
| 190 | PRKACA | 0.30847204 |
| 191 | PRKCE | 0.29195932 |
| 192 | MAP3K11 | 0.28577107 |
| 193 | PRKACB | 0.27888403 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.90652913 |
| 2 | Parkinsons disease_Homo sapiens_hsa05012 | 3.61184785 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.57896780 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.47006093 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.32464968 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 2.87935121 |
| 7 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.68401775 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.61143597 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.49558832 |
| 10 | Other glycan degradation_Homo sapiens_hsa00511 | 2.36255983 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.22108777 |
| 12 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.10328959 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.09860661 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 2.05724679 |
| 15 | Leishmaniasis_Homo sapiens_hsa05140 | 1.98350982 |
| 16 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.82853634 |
| 17 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.77769665 |
| 18 | Spliceosome_Homo sapiens_hsa03040 | 1.76867167 |
| 19 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.76749625 |
| 20 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.76177993 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.73637871 |
| 22 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.71997411 |
| 23 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.71799305 |
| 24 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.70840926 |
| 25 | Allograft rejection_Homo sapiens_hsa05330 | 1.64953343 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.60251748 |
| 27 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.59630260 |
| 28 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.59456295 |
| 29 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.59193206 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.58786227 |
| 31 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.55260459 |
| 32 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.54494401 |
| 33 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.52614987 |
| 34 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.50848365 |
| 35 | Homologous recombination_Homo sapiens_hsa03440 | 1.49886114 |
| 36 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.46971525 |
| 37 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.42577875 |
| 38 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.42472686 |
| 39 | DNA replication_Homo sapiens_hsa03030 | 1.41008680 |
| 40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38727719 |
| 41 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.36386506 |
| 42 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.35173969 |
| 43 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.34846420 |
| 44 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.34111807 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.32283159 |
| 46 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.32163375 |
| 47 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.31536777 |
| 48 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.29981526 |
| 49 | Asthma_Homo sapiens_hsa05310 | 1.24236458 |
| 50 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.23298419 |
| 51 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.23279771 |
| 52 | Influenza A_Homo sapiens_hsa05164 | 1.22493511 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.22122244 |
| 54 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.21351809 |
| 55 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.21286288 |
| 56 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.20780476 |
| 57 | Measles_Homo sapiens_hsa05162 | 1.18776765 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.16064706 |
| 59 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.15817266 |
| 60 | Tuberculosis_Homo sapiens_hsa05152 | 1.15667457 |
| 61 | Platelet activation_Homo sapiens_hsa04611 | 1.15350418 |
| 62 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.14193581 |
| 63 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.14181199 |
| 64 | Peroxisome_Homo sapiens_hsa04146 | 1.13850936 |
| 65 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.13395270 |
| 66 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.13373798 |
| 67 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.12986785 |
| 68 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.09913693 |
| 69 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.08844028 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.08758078 |
| 71 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.08654714 |
| 72 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.08557464 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 1.08347171 |
| 74 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.08231947 |
| 75 | RNA degradation_Homo sapiens_hsa03018 | 1.07719029 |
| 76 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.07601588 |
| 77 | Mismatch repair_Homo sapiens_hsa03430 | 1.06496304 |
| 78 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.05625488 |
| 79 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.04779942 |
| 80 | Nicotine addiction_Homo sapiens_hsa05033 | 1.03496191 |
| 81 | Hepatitis B_Homo sapiens_hsa05161 | 1.03018040 |
| 82 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.02652203 |
| 83 | Hepatitis C_Homo sapiens_hsa05160 | 1.02185764 |
| 84 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.01383801 |
| 85 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.00439331 |
| 86 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.99588334 |
| 87 | ABC transporters_Homo sapiens_hsa02010 | 0.99572666 |
| 88 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.99437408 |
| 89 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.98928112 |
| 90 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.98750007 |
| 91 | Axon guidance_Homo sapiens_hsa04360 | 0.98719708 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.97359374 |
| 93 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.96653509 |
| 94 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.96309881 |
| 95 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.96208957 |
| 96 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.96056317 |
| 97 | Basal transcription factors_Homo sapiens_hsa03022 | 0.95325861 |
| 98 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.94792182 |
| 99 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.94173799 |
| 100 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.94025192 |
| 101 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.93870316 |
| 102 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.93578722 |
| 103 | Insulin resistance_Homo sapiens_hsa04931 | 0.93571061 |
| 104 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.93482973 |
| 105 | Endometrial cancer_Homo sapiens_hsa05213 | 0.93167719 |
| 106 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.92582830 |
| 107 | Viral myocarditis_Homo sapiens_hsa05416 | 0.90688437 |
| 108 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90445897 |
| 109 | GABAergic synapse_Homo sapiens_hsa04727 | 0.87817936 |
| 110 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.87672762 |
| 111 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.86658059 |
| 112 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.86289899 |
| 113 | Colorectal cancer_Homo sapiens_hsa05210 | 0.85811038 |
| 114 | Sulfur relay system_Homo sapiens_hsa04122 | 0.85386458 |
| 115 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.84389888 |
| 116 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.84179607 |
| 117 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.83726324 |
| 118 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.82778952 |
| 119 | Metabolic pathways_Homo sapiens_hsa01100 | 0.82307828 |
| 120 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.81897469 |
| 121 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.81131829 |
| 122 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.80340248 |
| 123 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.80016737 |
| 124 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.79719877 |
| 125 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.79572912 |
| 126 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.79349670 |
| 127 | Long-term potentiation_Homo sapiens_hsa04720 | 0.78913000 |
| 128 | Malaria_Homo sapiens_hsa05144 | 0.78267912 |
| 129 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.77954759 |
| 130 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.77884180 |
| 131 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.77672116 |
| 132 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.76564039 |
| 133 | Circadian entrainment_Homo sapiens_hsa04713 | 0.76551287 |
| 134 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.75752748 |
| 135 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.75384678 |
| 136 | Base excision repair_Homo sapiens_hsa03410 | 0.74486050 |
| 137 | Pertussis_Homo sapiens_hsa05133 | 0.74294709 |
| 138 | Histidine metabolism_Homo sapiens_hsa00340 | 0.73876761 |
| 139 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73498704 |
| 140 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.72692702 |
| 141 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.72324886 |
| 142 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.72257968 |
| 143 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.71900568 |
| 144 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.70358091 |
| 145 | Prostate cancer_Homo sapiens_hsa05215 | 0.70045338 |
| 146 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69469655 |
| 147 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.68316506 |
| 148 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68224673 |
| 149 | Glioma_Homo sapiens_hsa05214 | 0.67643897 |
| 150 | Amoebiasis_Homo sapiens_hsa05146 | 0.66737419 |
| 151 | HTLV-I infection_Homo sapiens_hsa05166 | 0.66629304 |
| 152 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.65906042 |
| 153 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.65078313 |
| 154 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63072390 |
| 155 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.62895621 |
| 156 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.61915913 |
| 157 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.61573744 |
| 158 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61131114 |
| 159 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.61035039 |
| 160 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59613629 |
| 161 | Apoptosis_Homo sapiens_hsa04210 | 0.59521773 |
| 162 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58779718 |
| 163 | RNA transport_Homo sapiens_hsa03013 | 0.58328707 |
| 164 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.58309644 |
| 165 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.56021260 |
| 166 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.55916053 |
| 167 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.53962343 |
| 168 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.53783227 |
| 169 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.52025426 |
| 170 | Alcoholism_Homo sapiens_hsa05034 | 0.49175367 |
| 171 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.48909270 |
| 172 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.48240154 |
| 173 | Lysine degradation_Homo sapiens_hsa00310 | 0.48156591 |
| 174 | Cell cycle_Homo sapiens_hsa04110 | 0.48153673 |
| 175 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47908015 |
| 176 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.47218874 |
| 177 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.47115820 |
| 178 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.46742179 |
| 179 | Focal adhesion_Homo sapiens_hsa04510 | 0.46372940 |
| 180 | Taste transduction_Homo sapiens_hsa04742 | 0.46088644 |
| 181 | Renin secretion_Homo sapiens_hsa04924 | 0.45830541 |
| 182 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.45225500 |
| 183 | Morphine addiction_Homo sapiens_hsa05032 | 0.44829817 |
| 184 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.44657365 |
| 185 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.43761683 |
| 186 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.43489348 |
| 187 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.40920727 |
| 188 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40156548 |
| 189 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.40010465 |
| 190 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.39864666 |
| 191 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.37958963 |
| 192 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.37190657 |
| 193 | Cocaine addiction_Homo sapiens_hsa05030 | 0.37049782 |
| 194 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.35656545 |
| 195 | Gap junction_Homo sapiens_hsa04540 | 0.35256485 |
| 196 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33144932 |
| 197 | Long-term depression_Homo sapiens_hsa04730 | 0.30954072 |
| 198 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.29343153 |
| 199 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.28208589 |

