Rank | Gene Set | Z-score |
---|---|---|
1 | plasma membrane repair (GO:0001778) | 4.28217987 |
2 | COPI coating of Golgi vesicle (GO:0048205) | 3.82846292 |
3 | Golgi transport vesicle coating (GO:0048200) | 3.82846292 |
4 | positive regulation of histone deacetylation (GO:0031065) | 3.78489406 |
5 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.71376553 |
6 | stress fiber assembly (GO:0043149) | 3.66468466 |
7 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.62151818 |
8 | mannose metabolic process (GO:0006013) | 3.61188046 |
9 | apoptotic cell clearance (GO:0043277) | 3.56616723 |
10 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.52154845 |
11 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.51896946 |
12 | protein heterotrimerization (GO:0070208) | 3.45482385 |
13 | cell adhesion mediated by integrin (GO:0033627) | 3.44041399 |
14 | endodermal cell differentiation (GO:0035987) | 3.39922633 |
15 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 3.35897675 |
16 | adherens junction assembly (GO:0034333) | 3.35058573 |
17 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 3.31898880 |
18 | epithelial cell-cell adhesion (GO:0090136) | 3.31768570 |
19 | cell-substrate junction assembly (GO:0007044) | 3.27864100 |
20 | protein localization to endosome (GO:0036010) | 3.27222839 |
21 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.26905641 |
22 | skin morphogenesis (GO:0043589) | 3.25909849 |
23 | peptidyl-lysine dimethylation (GO:0018027) | 3.25833211 |
24 | positive regulation of nuclease activity (GO:0032075) | 3.23410745 |
25 | regulation of extracellular matrix disassembly (GO:0010715) | 3.18729029 |
26 | cardiac myofibril assembly (GO:0055003) | 3.14066965 |
27 | activation of Rac GTPase activity (GO:0032863) | 3.12620747 |
28 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.09281737 |
29 | cortical actin cytoskeleton organization (GO:0030866) | 3.07298871 |
30 | peptidyl-proline hydroxylation (GO:0019511) | 2.94779990 |
31 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.94125262 |
32 | basement membrane organization (GO:0071711) | 2.93448188 |
33 | semaphorin-plexin signaling pathway (GO:0071526) | 2.92938476 |
34 | endothelial cell chemotaxis (GO:0035767) | 2.92907903 |
35 | axon extension involved in axon guidance (GO:0048846) | 2.91629189 |
36 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.91629189 |
37 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.90854270 |
38 | protein hydroxylation (GO:0018126) | 2.90539838 |
39 | pinocytosis (GO:0006907) | 2.90289722 |
40 | sarcomere organization (GO:0045214) | 2.90121786 |
41 | proline biosynthetic process (GO:0006561) | 2.89582024 |
42 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.89123473 |
43 | regulation of nuclease activity (GO:0032069) | 2.88539726 |
44 | regulation of tight junction assembly (GO:2000810) | 2.87903393 |
45 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.85631653 |
46 | collagen fibril organization (GO:0030199) | 2.85442020 |
47 | barbed-end actin filament capping (GO:0051016) | 2.84420615 |
48 | regulation of histone H3-K27 methylation (GO:0061085) | 2.84299961 |
49 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.84256847 |
50 | positive regulation of receptor recycling (GO:0001921) | 2.83246110 |
51 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.82155029 |
52 | negative regulation of heart growth (GO:0061117) | 2.80867219 |
53 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 2.80867219 |
54 | focal adhesion assembly (GO:0048041) | 2.80366500 |
55 | cell-substrate adherens junction assembly (GO:0007045) | 2.80366500 |
56 | receptor catabolic process (GO:0032801) | 2.80176226 |
57 | protein retention in ER lumen (GO:0006621) | 2.79845217 |
58 | germ cell migration (GO:0008354) | 2.78116898 |
59 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.77065618 |
60 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.76588257 |
61 | hippo signaling (GO:0035329) | 2.75842191 |
62 | regulation of early endosome to late endosome transport (GO:2000641) | 2.75609177 |
63 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.74069657 |
64 | desmosome organization (GO:0002934) | 2.72476815 |
65 | positive regulation of keratinocyte differentiation (GO:0045618) | 2.71609672 |
66 | embryonic process involved in female pregnancy (GO:0060136) | 2.71183880 |
67 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.71095966 |
68 | growth hormone receptor signaling pathway (GO:0060396) | 2.70174312 |
69 | morphogenesis of an endothelium (GO:0003159) | 2.69109793 |
70 | endothelial tube morphogenesis (GO:0061154) | 2.69109793 |
71 | modulation by symbiont of host cellular process (GO:0044068) | 2.68860209 |
72 | positive regulation of protein deacetylation (GO:0090312) | 2.67370044 |
73 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.67039568 |
74 | cellular response to unfolded protein (GO:0034620) | 2.66940486 |
75 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.61271547 |
76 | ER-nucleus signaling pathway (GO:0006984) | 2.61026463 |
77 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.58239670 |
78 | chondrocyte proliferation (GO:0035988) | 2.58059496 |
79 | pentose-phosphate shunt (GO:0006098) | 2.57773567 |
80 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.57093974 |
81 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.56707472 |
82 | * negative regulation of cell size (GO:0045792) | 2.54103452 |
83 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.53805798 |
84 | response to laminar fluid shear stress (GO:0034616) | 2.53619656 |
85 | glucose 6-phosphate metabolic process (GO:0051156) | 2.53120130 |
86 | embryonic eye morphogenesis (GO:0048048) | 2.52749177 |
87 | hemidesmosome assembly (GO:0031581) | 2.52361909 |
88 | atrioventricular valve morphogenesis (GO:0003181) | 2.51895198 |
89 | negative regulation of viral release from host cell (GO:1902187) | 2.51609661 |
90 | ear development (GO:0043583) | 2.50783470 |
91 | modulation by virus of host morphology or physiology (GO:0019048) | 2.50185673 |
92 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.49771670 |
93 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.49771670 |
94 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.48358324 |
95 | 4-hydroxyproline metabolic process (GO:0019471) | 2.48041989 |
96 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.47276580 |
97 | blood vessel endothelial cell migration (GO:0043534) | 2.46939714 |
98 | polarized epithelial cell differentiation (GO:0030859) | 2.46153662 |
99 | collagen metabolic process (GO:0032963) | 2.45574225 |
100 | regulation of hippo signaling (GO:0035330) | 2.45096552 |
101 | cortical cytoskeleton organization (GO:0030865) | 2.44927464 |
102 | glucose catabolic process (GO:0006007) | 2.44577609 |
103 | substrate-dependent cell migration (GO:0006929) | 2.43520276 |
104 | cell-cell junction maintenance (GO:0045217) | 2.42232148 |
105 | platelet aggregation (GO:0070527) | 2.42225845 |
106 | heterochromatin organization (GO:0070828) | 2.41479629 |
107 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.41339452 |
108 | modulation by virus of host process (GO:0019054) | 2.41212826 |
109 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.40413445 |
110 | surfactant homeostasis (GO:0043129) | 2.40035687 |
111 | cellular response to topologically incorrect protein (GO:0035967) | 2.39800291 |
112 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.39426499 |
113 | extracellular matrix disassembly (GO:0022617) | 2.39150864 |
114 | embryonic foregut morphogenesis (GO:0048617) | 2.38525843 |
115 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.38147474 |
116 | * positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.37771891 |
117 | glial cell proliferation (GO:0014009) | 2.37402302 |
118 | regulation of extracellular matrix organization (GO:1903053) | 2.37324297 |
119 | cellular response to growth hormone stimulus (GO:0071378) | 2.37204287 |
120 | corticosteroid receptor signaling pathway (GO:0031958) | 2.36918298 |
121 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.36405203 |
122 | regulation of translational termination (GO:0006449) | 2.35670769 |
123 | amyloid precursor protein catabolic process (GO:0042987) | 2.35159726 |
124 | collagen catabolic process (GO:0030574) | 2.34804452 |
125 | positive regulation of extracellular matrix organization (GO:1903055) | 2.34558294 |
126 | heart trabecula formation (GO:0060347) | 2.34152069 |
127 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.33328866 |
128 | protein targeting to plasma membrane (GO:0072661) | 2.33278027 |
129 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.33246820 |
130 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.32965756 |
131 | apoptotic process involved in morphogenesis (GO:0060561) | 2.32742837 |
132 | positive regulation of p38MAPK cascade (GO:1900745) | 2.32690452 |
133 | mRNA stabilization (GO:0048255) | 2.32671674 |
134 | RNA stabilization (GO:0043489) | 2.32671674 |
135 | regulation of p38MAPK cascade (GO:1900744) | 2.32266494 |
136 | positive regulation of lamellipodium assembly (GO:0010592) | 2.31824955 |
137 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.30202109 |
138 | regulation of translational fidelity (GO:0006450) | 2.29616510 |
139 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.29601882 |
140 | positive regulation of lamellipodium organization (GO:1902745) | 2.29453174 |
141 | regulation of defense response to virus by virus (GO:0050690) | 2.29124720 |
142 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.28285502 |
143 | hypotonic response (GO:0006971) | 2.27336206 |
144 | positive regulation of protein dephosphorylation (GO:0035307) | 2.25483267 |
145 | regulation of ARF GTPase activity (GO:0032312) | 2.24686479 |
146 | actin filament bundle assembly (GO:0051017) | 2.24449224 |
147 | actin filament bundle organization (GO:0061572) | 2.24449224 |
148 | embryonic camera-type eye morphogenesis (GO:0048596) | 2.23522348 |
149 | activation of JUN kinase activity (GO:0007257) | 2.21774562 |
150 | membrane protein ectodomain proteolysis (GO:0006509) | 2.21103855 |
151 | NADPH regeneration (GO:0006740) | 2.20969635 |
152 | embryo implantation (GO:0007566) | 2.18920310 |
153 | Rho protein signal transduction (GO:0007266) | 2.18321450 |
154 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.18307028 |
155 | eye morphogenesis (GO:0048592) | 2.15945684 |
156 | regulation of cholesterol homeostasis (GO:2000188) | 2.14945072 |
157 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.14207988 |
158 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.12230112 |
159 | response to water (GO:0009415) | 2.11894837 |
160 | regulation of lipid kinase activity (GO:0043550) | 2.10894666 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 4.03807634 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.21918172 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 3.07780004 |
4 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.01221864 |
5 | * EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.79259806 |
6 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.68062440 |
7 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.65032148 |
8 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.50177235 |
9 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.44389060 |
10 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.36797209 |
11 | * CLOCK_20551151_ChIP-Seq_293T_Human | 2.33767472 |
12 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.30091879 |
13 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.23031154 |
14 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.17863834 |
15 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.15951647 |
16 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.04279885 |
17 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.03481857 |
18 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.00011187 |
19 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.99651911 |
20 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.95879792 |
21 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.95728416 |
22 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.92408001 |
23 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.91482758 |
24 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.90296246 |
25 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.90218209 |
26 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.89743617 |
27 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.87115312 |
28 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.84757628 |
29 | KDM2B_26808549_Chip-Seq_K562_Human | 1.76327536 |
30 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.75948392 |
31 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.75419132 |
32 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.74241051 |
33 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.74178064 |
34 | MAF_26560356_Chip-Seq_TH1_Human | 1.64621206 |
35 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.64191072 |
36 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.62203812 |
37 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.61360596 |
38 | UTX_26944678_Chip-Seq_JUKART_Human | 1.61336688 |
39 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.60849615 |
40 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.58253799 |
41 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.54188667 |
42 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.53767401 |
43 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.52633595 |
44 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.51196846 |
45 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.50758965 |
46 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.50345503 |
47 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.49713506 |
48 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.47732008 |
49 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.44970765 |
50 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.44158991 |
51 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.42105152 |
52 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.40963761 |
53 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.40963761 |
54 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.39928131 |
55 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.37023040 |
56 | SPI1_23127762_ChIP-Seq_K562_Human | 1.36742450 |
57 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.36600464 |
58 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.36403819 |
59 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.35857769 |
60 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.34487208 |
61 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.32471825 |
62 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.30473316 |
63 | * SMC4_20622854_ChIP-Seq_HELA_Human | 1.29873400 |
64 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.29853283 |
65 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.27871010 |
66 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.27241785 |
67 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.26805556 |
68 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.26394174 |
69 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.23471344 |
70 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.23452176 |
71 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.23121406 |
72 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.22811482 |
73 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.22053037 |
74 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.21917747 |
75 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.21213290 |
76 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.20091932 |
77 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.17098842 |
78 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.17029288 |
79 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.16997182 |
80 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.15911447 |
81 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.13927670 |
82 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.13655029 |
83 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.13289095 |
84 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.12134598 |
85 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.11864157 |
86 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.10852064 |
87 | GATA1_19941826_ChIP-Seq_K562_Human | 1.10505492 |
88 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.10318167 |
89 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.09815437 |
90 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.09116300 |
91 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07884359 |
92 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.07001357 |
93 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.06818798 |
94 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.05250393 |
95 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05154793 |
96 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.03990460 |
97 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.03624285 |
98 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.03422209 |
99 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.03137939 |
100 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.03137939 |
101 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.02580891 |
102 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.02233234 |
103 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.01709260 |
104 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.01470041 |
105 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.01128861 |
106 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.01039899 |
107 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00154450 |
108 | P68_20966046_ChIP-Seq_HELA_Human | 0.99941593 |
109 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.99297461 |
110 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.99187036 |
111 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98931479 |
112 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.98753068 |
113 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.98673294 |
114 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.98207371 |
115 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.97598088 |
116 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.96258780 |
117 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.95862876 |
118 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94906308 |
119 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.94765182 |
120 | * SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.94726399 |
121 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.93245959 |
122 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.92583557 |
123 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.91882982 |
124 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.91333266 |
125 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.90957072 |
126 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.90901101 |
127 | * MAF_26560356_Chip-Seq_TH2_Human | 0.90741657 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 4.28540582 |
2 | * MP0003705_abnormal_hypodermis_morpholog | 3.48490398 |
3 | MP0003300_gastrointestinal_ulcer | 2.96644424 |
4 | MP0003566_abnormal_cell_adhesion | 2.74849137 |
5 | MP0005451_abnormal_body_composition | 2.69776395 |
6 | MP0010352_gastrointestinal_tract_polyps | 2.60855411 |
7 | MP0002877_abnormal_melanocyte_morpholog | 2.60705944 |
8 | MP0003279_aneurysm | 2.56005527 |
9 | MP0005409_darkened_coat_color | 2.50008156 |
10 | MP0003303_peritoneal_inflammation | 2.47074826 |
11 | MP0006054_spinal_hemorrhage | 2.45460924 |
12 | MP0005623_abnormal_meninges_morphology | 2.45355197 |
13 | MP0005275_abnormal_skin_tensile | 2.33272774 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.33152988 |
15 | MP0001958_emphysema | 2.23764525 |
16 | MP0005076_abnormal_cell_differentiation | 2.23489046 |
17 | MP0004084_abnormal_cardiac_muscle | 2.13331301 |
18 | MP0004272_abnormal_basement_membrane | 2.11026471 |
19 | MP0009278_abnormal_bone_marrow | 2.07605130 |
20 | MP0010234_abnormal_vibrissa_follicle | 2.01742521 |
21 | MP0008260_abnormal_autophagy | 1.96771509 |
22 | MP0002796_impaired_skin_barrier | 1.83030350 |
23 | MP0003453_abnormal_keratinocyte_physiol | 1.82549573 |
24 | * MP0000733_abnormal_muscle_development | 1.80117497 |
25 | MP0000751_myopathy | 1.72833204 |
26 | MP0003091_abnormal_cell_migration | 1.71225851 |
27 | MP0005023_abnormal_wound_healing | 1.67646324 |
28 | MP0005503_abnormal_tendon_morphology | 1.65745883 |
29 | MP0005257_abnormal_intraocular_pressure | 1.64007889 |
30 | MP0004264_abnormal_extraembryonic_tissu | 1.62628594 |
31 | MP0001849_ear_inflammation | 1.59307190 |
32 | MP0004510_myositis | 1.51840557 |
33 | MP0004808_abnormal_hematopoietic_stem | 1.50736536 |
34 | * MP0004087_abnormal_muscle_fiber | 1.45043621 |
35 | MP0000750_abnormal_muscle_regeneration | 1.45003697 |
36 | MP0010368_abnormal_lymphatic_system | 1.44270953 |
37 | MP0004381_abnormal_hair_follicle | 1.44127720 |
38 | MP0002249_abnormal_larynx_morphology | 1.37759535 |
39 | MP0000678_abnormal_parathyroid_gland | 1.36387203 |
40 | MP0004858_abnormal_nervous_system | 1.36120293 |
41 | * MP0010630_abnormal_cardiac_muscle | 1.35645104 |
42 | MP0000767_abnormal_smooth_muscle | 1.33909380 |
43 | MP0005501_abnormal_skin_physiology | 1.33316825 |
44 | MP0000537_abnormal_urethra_morphology | 1.32423953 |
45 | MP0003283_abnormal_digestive_organ | 1.28823985 |
46 | MP0002837_dystrophic_cardiac_calcinosis | 1.28710212 |
47 | MP0004185_abnormal_adipocyte_glucose | 1.23083182 |
48 | MP0008961_abnormal_basal_metabolism | 1.22496642 |
49 | MP0003045_fibrosis | 1.21573632 |
50 | MP0002896_abnormal_bone_mineralization | 1.17777640 |
51 | MP0003329_amyloid_beta_deposits | 1.16496839 |
52 | MP0000569_abnormal_digit_pigmentation | 1.16377880 |
53 | MP0004130_abnormal_muscle_cell | 1.15601592 |
54 | MP0002089_abnormal_postnatal_growth/wei | 1.13638012 |
55 | MP0009384_cardiac_valve_regurgitation | 1.12472188 |
56 | MP0003115_abnormal_respiratory_system | 1.12454809 |
57 | MP0000003_abnormal_adipose_tissue | 1.10108762 |
58 | MP0010307_abnormal_tumor_latency | 1.09775402 |
59 | MP0009053_abnormal_anal_canal | 1.08812162 |
60 | MP0004782_abnormal_surfactant_physiolog | 1.07476651 |
61 | MP0002128_abnormal_blood_circulation | 1.07357655 |
62 | MP0005330_cardiomyopathy | 1.06987856 |
63 | MP0002925_abnormal_cardiovascular_devel | 1.06465076 |
64 | MP0004233_abnormal_muscle_weight | 1.05921827 |
65 | MP0000013_abnormal_adipose_tissue | 1.05253061 |
66 | MP0002060_abnormal_skin_morphology | 1.02797510 |
67 | MP0009780_abnormal_chondrocyte_physiolo | 1.02484918 |
68 | MP0000428_abnormal_craniofacial_morphol | 1.02231741 |
69 | MP0001544_abnormal_cardiovascular_syste | 1.01802305 |
70 | MP0005385_cardiovascular_system_phenoty | 1.01802305 |
71 | MP0002098_abnormal_vibrissa_morphology | 1.01075870 |
72 | MP0005058_abnormal_lysosome_morphology | 1.00408555 |
73 | MP0003828_pulmonary_edema | 0.99765857 |
74 | MP0001915_intracranial_hemorrhage | 0.99663439 |
75 | MP0000467_abnormal_esophagus_morphology | 0.99232949 |
76 | MP0001348_abnormal_lacrimal_gland | 0.99196392 |
77 | MP0006138_congestive_heart_failure | 0.98810346 |
78 | MP0003567_abnormal_fetal_cardiomyocyte | 0.98265508 |
79 | MP0001879_abnormal_lymphatic_vessel | 0.96504357 |
80 | MP0000759_abnormal_skeletal_muscle | 0.96443037 |
81 | MP0003385_abnormal_body_wall | 0.94855270 |
82 | MP0005375_adipose_tissue_phenotype | 0.94780501 |
83 | MP0004947_skin_inflammation | 0.94676087 |
84 | MP0002234_abnormal_pharynx_morphology | 0.94654499 |
85 | MP0001873_stomach_inflammation | 0.94094535 |
86 | MP0000747_muscle_weakness | 0.93998346 |
87 | * MP0000266_abnormal_heart_morphology | 0.91351143 |
88 | MP0001614_abnormal_blood_vessel | 0.91175403 |
89 | MP0005621_abnormal_cell_physiology | 0.90500653 |
90 | MP0004036_abnormal_muscle_relaxation | 0.90475234 |
91 | MP0008775_abnormal_heart_ventricle | 0.89301089 |
92 | MP0002972_abnormal_cardiac_muscle | 0.89251972 |
93 | MP0000858_altered_metastatic_potential | 0.89232075 |
94 | MP0005167_abnormal_blood-brain_barrier | 0.89048740 |
95 | MP0005508_abnormal_skeleton_morphology | 0.88551741 |
96 | * MP0004197_abnormal_fetal_growth/weight/ | 0.88444223 |
97 | MP0001545_abnormal_hematopoietic_system | 0.88077019 |
98 | MP0005397_hematopoietic_system_phenotyp | 0.88077019 |
99 | MP0000534_abnormal_ureter_morphology | 0.86536950 |
100 | MP0010030_abnormal_orbit_morphology | 0.85098132 |
101 | MP0003436_decreased_susceptibility_to | 0.84995906 |
102 | * MP0001216_abnormal_epidermal_layer | 0.84269340 |
103 | MP0003448_altered_tumor_morphology | 0.84042989 |
104 | MP0000462_abnormal_digestive_system | 0.83879314 |
105 | * MP0009931_abnormal_skin_appearance | 0.83851182 |
106 | MP0002998_abnormal_bone_remodeling | 0.83029983 |
107 | MP0003123_paternal_imprinting | 0.82825115 |
108 | MP0001533_abnormal_skeleton_physiology | 0.82555429 |
109 | MP0003172_abnormal_lysosome_physiology | 0.82504250 |
110 | MP0009840_abnormal_foam_cell | 0.82380344 |
111 | MP0002933_joint_inflammation | 0.82302936 |
112 | MP0000627_abnormal_mammary_gland | 0.80989906 |
113 | MP0003763_abnormal_thymus_physiology | 0.80648427 |
114 | MP0002269_muscular_atrophy | 0.80499699 |
115 | MP0003183_abnormal_peptide_metabolism | 0.79513251 |
116 | MP0005666_abnormal_adipose_tissue | 0.79401983 |
117 | MP0003221_abnormal_cardiomyocyte_apopto | 0.78197480 |
118 | MP0000490_abnormal_crypts_of | 0.76031255 |
119 | MP0000685_abnormal_immune_system | 0.75637247 |
120 | MP0003942_abnormal_urinary_system | 0.75197994 |
121 | MP0002106_abnormal_muscle_physiology | 0.74945228 |
122 | * MP0002086_abnormal_extraembryonic_tissu | 0.74632856 |
123 | MP0002396_abnormal_hematopoietic_system | 0.74396071 |
124 | MP0000343_altered_response_to | 0.74236462 |
125 | MP0005464_abnormal_platelet_physiology | 0.74112523 |
126 | MP0005390_skeleton_phenotype | 0.73678353 |
127 | MP0001243_abnormal_dermal_layer | 0.72142547 |
128 | MP0002166_altered_tumor_susceptibility | 0.69416388 |
129 | MP0002108_abnormal_muscle_morphology | 0.69125099 |
130 | MP0001730_embryonic_growth_arrest | 0.69002715 |
131 | MP0000579_abnormal_nail_morphology | 0.68817730 |
132 | MP0010155_abnormal_intestine_physiology | 0.67391969 |
133 | MP0001881_abnormal_mammary_gland | 0.66565901 |
134 | MP0000477_abnormal_intestine_morphology | 0.63694278 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 5.20751283 |
2 | Premature rupture of membranes (HP:0001788) | 4.33067713 |
3 | Cerebral aneurysm (HP:0004944) | 4.21680349 |
4 | Shallow orbits (HP:0000586) | 3.97188149 |
5 | Ankle contracture (HP:0006466) | 3.52536071 |
6 | Hyperacusis (HP:0010780) | 3.31421848 |
7 | Bladder diverticulum (HP:0000015) | 3.18430394 |
8 | Broad face (HP:0000283) | 3.11594492 |
9 | Dilatation of the ascending aorta (HP:0005111) | 3.04812091 |
10 | Aortic aneurysm (HP:0004942) | 3.04394062 |
11 | Aortic dissection (HP:0002647) | 3.01722316 |
12 | Mitral valve prolapse (HP:0001634) | 2.97270890 |
13 | Peritonitis (HP:0002586) | 2.92842989 |
14 | Increased connective tissue (HP:0009025) | 2.89567692 |
15 | Broad metatarsal (HP:0001783) | 2.86951819 |
16 | Cervical subluxation (HP:0003308) | 2.84237591 |
17 | Flat acetabular roof (HP:0003180) | 2.77349236 |
18 | Atrophic scars (HP:0001075) | 2.76827680 |
19 | Subacute progressive viral hepatitis (HP:0006572) | 2.72937489 |
20 | Aneurysm (HP:0002617) | 2.71081305 |
21 | Increased density of long bones (HP:0006392) | 2.70564951 |
22 | Genu recurvatum (HP:0002816) | 2.70043853 |
23 | Distal upper limb amyotrophy (HP:0007149) | 2.70025572 |
24 | Upper limb amyotrophy (HP:0009129) | 2.70025572 |
25 | Distal lower limb muscle weakness (HP:0009053) | 2.67614291 |
26 | Bowel diverticulosis (HP:0005222) | 2.63633361 |
27 | Fragile skin (HP:0001030) | 2.58528454 |
28 | Type 1 muscle fiber predominance (HP:0003803) | 2.53883721 |
29 | J-shaped sella turcica (HP:0002680) | 2.52398080 |
30 | Obstructive sleep apnea (HP:0002870) | 2.50335392 |
31 | Difficulty climbing stairs (HP:0003551) | 2.44787401 |
32 | Long toe (HP:0010511) | 2.35136413 |
33 | Hand muscle atrophy (HP:0009130) | 2.33950190 |
34 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.32694224 |
35 | Short 4th metacarpal (HP:0010044) | 2.32694224 |
36 | Asymmetric septal hypertrophy (HP:0001670) | 2.31496668 |
37 | Ulnar bowing (HP:0003031) | 2.31445713 |
38 | Scapular winging (HP:0003691) | 2.29072315 |
39 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.23788255 |
40 | Renal duplication (HP:0000075) | 2.23369854 |
41 | Biconcave vertebral bodies (HP:0004586) | 2.22053930 |
42 | Wormian bones (HP:0002645) | 2.20793338 |
43 | Right ventricular cardiomyopathy (HP:0011663) | 2.20070367 |
44 | Wrist flexion contracture (HP:0001239) | 2.17521236 |
45 | Increased variability in muscle fiber diameter (HP:0003557) | 2.16995882 |
46 | Striae distensae (HP:0001065) | 2.15925607 |
47 | Elfin facies (HP:0004428) | 2.15312883 |
48 | Blue sclerae (HP:0000592) | 2.14132963 |
49 | Hemorrhage of the eye (HP:0011885) | 2.13829010 |
50 | Spinal rigidity (HP:0003306) | 2.12182201 |
51 | Short nail (HP:0001799) | 2.11429269 |
52 | Achilles tendon contracture (HP:0001771) | 2.10448369 |
53 | Radial bowing (HP:0002986) | 2.09765011 |
54 | Renovascular hypertension (HP:0100817) | 2.09281021 |
55 | Soft skin (HP:0000977) | 2.07714952 |
56 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.05917052 |
57 | Abnormality of the 4th metacarpal (HP:0010012) | 2.05472216 |
58 | Long palpebral fissure (HP:0000637) | 2.05329715 |
59 | Rectal prolapse (HP:0002035) | 2.00208144 |
60 | Hematochezia (HP:0002573) | 1.99299821 |
61 | Limb-girdle muscle atrophy (HP:0003797) | 1.98581650 |
62 | Disproportionate tall stature (HP:0001519) | 1.98506245 |
63 | Insomnia (HP:0100785) | 1.98488363 |
64 | Sudden death (HP:0001699) | 1.97874870 |
65 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.97832001 |
66 | Osteolytic defects of the hand bones (HP:0009699) | 1.97832001 |
67 | Vascular tortuosity (HP:0004948) | 1.97255892 |
68 | Camptodactyly of toe (HP:0001836) | 1.96350247 |
69 | * Deviation of the hallux (HP:0010051) | 1.96171863 |
70 | Interstitial pulmonary disease (HP:0006530) | 1.94296558 |
71 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.93826125 |
72 | Mitral regurgitation (HP:0001653) | 1.93430524 |
73 | * Hallux valgus (HP:0001822) | 1.92516141 |
74 | Dysostosis multiplex (HP:0000943) | 1.92106564 |
75 | Bowing of the arm (HP:0006488) | 1.91525787 |
76 | Bowed forearm bones (HP:0003956) | 1.91525787 |
77 | Flat cornea (HP:0007720) | 1.91271819 |
78 | Hyperparathyroidism (HP:0000843) | 1.90462343 |
79 | Ventricular tachycardia (HP:0004756) | 1.90133445 |
80 | Abnormality of the thoracic spine (HP:0100711) | 1.89051922 |
81 | Distal lower limb amyotrophy (HP:0008944) | 1.88411142 |
82 | Vertebral compression fractures (HP:0002953) | 1.87821054 |
83 | Pointed chin (HP:0000307) | 1.86805833 |
84 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.85988688 |
85 | Abnormality of the Achilles tendon (HP:0005109) | 1.85114774 |
86 | Arterial tortuosity (HP:0005116) | 1.84431768 |
87 | Slender build (HP:0001533) | 1.84372703 |
88 | Hypercortisolism (HP:0001578) | 1.83970138 |
89 | Persistence of primary teeth (HP:0006335) | 1.83727659 |
90 | Abnormality of the peritoneum (HP:0002585) | 1.83407457 |
91 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.83055739 |
92 | Mucopolysacchariduria (HP:0008155) | 1.83055739 |
93 | Stridor (HP:0010307) | 1.83011043 |
94 | Overriding aorta (HP:0002623) | 1.82313590 |
95 | Sparse lateral eyebrow (HP:0005338) | 1.81658327 |
96 | Patellar dislocation (HP:0002999) | 1.81332973 |
97 | Hyperextensible skin (HP:0000974) | 1.79971155 |
98 | Cerebral inclusion bodies (HP:0100314) | 1.79870120 |
99 | Back pain (HP:0003418) | 1.79207560 |
100 | Abnormality of the calcaneus (HP:0008364) | 1.79070515 |
101 | Abnormality of the acetabulum (HP:0003170) | 1.78534424 |
102 | Hyporeflexia of lower limbs (HP:0002600) | 1.77933034 |
103 | Difficulty running (HP:0009046) | 1.77824474 |
104 | Deformed sella turcica (HP:0002681) | 1.77562065 |
105 | Bicuspid aortic valve (HP:0001647) | 1.77241440 |
106 | Abnormal ossification of hand bones (HP:0005921) | 1.76920887 |
107 | Lower limb amyotrophy (HP:0007210) | 1.74666120 |
108 | Cutaneous melanoma (HP:0012056) | 1.74011142 |
109 | Ankyloglossia (HP:0010296) | 1.73494986 |
110 | Subaortic stenosis (HP:0001682) | 1.73191278 |
111 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.73191278 |
112 | Cupped ribs (HP:0000887) | 1.73159392 |
113 | Exercise-induced muscle cramps (HP:0003710) | 1.73023583 |
114 | Advanced eruption of teeth (HP:0006288) | 1.72854445 |
115 | Elbow flexion contracture (HP:0002987) | 1.72219863 |
116 | Muscle fiber splitting (HP:0003555) | 1.72179577 |
117 | Cellulitis (HP:0100658) | 1.71732275 |
118 | Generalized amyotrophy (HP:0003700) | 1.71300912 |
119 | Absent frontal sinuses (HP:0002688) | 1.71272579 |
120 | Overgrowth (HP:0001548) | 1.70679048 |
121 | Dislocated radial head (HP:0003083) | 1.70585961 |
122 | Frequent falls (HP:0002359) | 1.70095146 |
123 | Coxa vara (HP:0002812) | 1.68620659 |
124 | Abnormality of the radial head (HP:0003995) | 1.67315845 |
125 | Eczematoid dermatitis (HP:0000976) | 1.67143175 |
126 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.66594250 |
127 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.66594250 |
128 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.66594250 |
129 | Abnormality of carpal bone ossification (HP:0006257) | 1.66408413 |
130 | Metaphyseal cupping (HP:0003021) | 1.66136039 |
131 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.64059903 |
132 | Abnormality of oral frenula (HP:0000190) | 1.63861801 |
133 | Thin ribs (HP:0000883) | 1.62980136 |
134 | Abnormality of dentin (HP:0010299) | 1.62030894 |
135 | Spinal cord lesions (HP:0100561) | 1.61926762 |
136 | Syringomyelia (HP:0003396) | 1.61926762 |
137 | Bundle branch block (HP:0011710) | 1.61509378 |
138 | Ectopia lentis (HP:0001083) | 1.60120283 |
139 | Bone pain (HP:0002653) | 1.59995717 |
140 | Joint laxity (HP:0001388) | 1.59553741 |
141 | Premature skin wrinkling (HP:0100678) | 1.59151695 |
142 | Abdominal distention (HP:0003270) | 1.58631284 |
143 | Esophageal varix (HP:0002040) | 1.58279504 |
144 | Arnold-Chiari malformation (HP:0002308) | 1.56980731 |
145 | Polygenic inheritance (HP:0010982) | 1.56708528 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EEF2K | 4.14113735 |
2 | TTN | 3.74198573 |
3 | * TRIB3 | 3.44031296 |
4 | MAP3K10 | 3.35813073 |
5 | SMG1 | 3.21189127 |
6 | ERN1 | 2.97130404 |
7 | PRPF4B | 2.90108375 |
8 | RIPK1 | 2.74564539 |
9 | PDGFRA | 2.44805432 |
10 | IRAK3 | 2.32312443 |
11 | EPHA2 | 2.29644070 |
12 | BMX | 1.96425572 |
13 | DMPK | 1.82523342 |
14 | SIK1 | 1.80473095 |
15 | SCYL2 | 1.78868970 |
16 | * PTK6 | 1.75152398 |
17 | DDR2 | 1.73014095 |
18 | PAK4 | 1.66990014 |
19 | TAOK1 | 1.52300931 |
20 | LATS1 | 1.46653815 |
21 | LATS2 | 1.40299342 |
22 | PAK2 | 1.38815158 |
23 | ALK | 1.37802581 |
24 | LMTK2 | 1.36820939 |
25 | EPHB1 | 1.36049304 |
26 | NME2 | 1.35944319 |
27 | KSR2 | 1.35817825 |
28 | PRKD3 | 1.31647384 |
29 | PTK2 | 1.31211126 |
30 | MAP3K13 | 1.29795717 |
31 | * LRRK2 | 1.28303565 |
32 | PRKD2 | 1.20461009 |
33 | TESK1 | 1.19920227 |
34 | EPHB2 | 1.17901036 |
35 | MAP4K1 | 1.16640321 |
36 | MAP2K3 | 1.16321988 |
37 | STK10 | 1.15077244 |
38 | PDGFRB | 1.08439844 |
39 | MARK2 | 1.07707171 |
40 | NEK1 | 1.07635928 |
41 | TGFBR2 | 1.03217358 |
42 | TAOK2 | 1.02794820 |
43 | ICK | 1.00228758 |
44 | PRKCH | 0.98561486 |
45 | * MTOR | 0.98458208 |
46 | SIK2 | 0.98402334 |
47 | MAP3K6 | 0.98012448 |
48 | MAP3K7 | 0.96592809 |
49 | CDK6 | 0.95777908 |
50 | RPS6KA4 | 0.94606848 |
51 | CAMK1D | 0.93473067 |
52 | NEK2 | 0.91886004 |
53 | FLT3 | 0.91363729 |
54 | * PKN2 | 0.91185450 |
55 | RIPK4 | 0.88746979 |
56 | MAP3K8 | 0.87027530 |
57 | IRAK4 | 0.85398759 |
58 | TYK2 | 0.84836327 |
59 | FGFR4 | 0.84585834 |
60 | ZAP70 | 0.83521924 |
61 | RPS6KA2 | 0.81003013 |
62 | ARAF | 0.80119978 |
63 | PAK6 | 0.79263126 |
64 | LIMK1 | 0.79072493 |
65 | * PDPK1 | 0.78564815 |
66 | CAMK1G | 0.77825690 |
67 | IRAK2 | 0.76954833 |
68 | MAPKAPK3 | 0.75340975 |
69 | RPS6KB2 | 0.74429136 |
70 | STK3 | 0.73716879 |
71 | TGFBR1 | 0.73694687 |
72 | * RET | 0.72343399 |
73 | CDK4 | 0.70003855 |
74 | NEK9 | 0.69994012 |
75 | FER | 0.69796376 |
76 | TYRO3 | 0.69317329 |
77 | PAK3 | 0.69266514 |
78 | JAK3 | 0.68691591 |
79 | MAPK11 | 0.68656499 |
80 | MST1R | 0.68514926 |
81 | SIK3 | 0.68299157 |
82 | MAP3K14 | 0.68199575 |
83 | CDK12 | 0.67656729 |
84 | CDK7 | 0.67387238 |
85 | MAP2K1 | 0.67331197 |
86 | FGFR1 | 0.67274613 |
87 | TRPM7 | 0.65885490 |
88 | EPHA3 | 0.65093828 |
89 | TNK2 | 0.64584647 |
90 | FGFR3 | 0.63354254 |
91 | PTK2B | 0.63208518 |
92 | ROCK1 | 0.61324834 |
93 | HCK | 0.61139122 |
94 | CDC42BPA | 0.61070535 |
95 | JAK1 | 0.60097885 |
96 | * ILK | 0.59424627 |
97 | PRKG2 | 0.59005475 |
98 | MAP2K2 | 0.58981100 |
99 | MAP3K1 | 0.58573676 |
100 | MAP3K11 | 0.57382537 |
101 | RPS6KA6 | 0.57339531 |
102 | MAP3K3 | 0.57227741 |
103 | * PRKD1 | 0.54496257 |
104 | DYRK1B | 0.53871711 |
105 | MOS | 0.53645365 |
106 | CSK | 0.52908014 |
107 | JAK2 | 0.50356481 |
108 | MAP3K2 | 0.49431821 |
109 | DAPK3 | 0.49277397 |
110 | STK38 | 0.48782113 |
111 | TESK2 | 0.48592469 |
112 | MAPK12 | 0.47770984 |
113 | GRK6 | 0.47043981 |
114 | NTRK1 | 0.46797943 |
115 | NEK6 | 0.46271106 |
116 | ROCK2 | 0.46155519 |
117 | KDR | 0.45642115 |
118 | MARK3 | 0.45442462 |
119 | BLK | 0.44246181 |
120 | BTK | 0.43815230 |
121 | MET | 0.42792108 |
122 | HIPK2 | 0.42401792 |
123 | STK24 | 0.42271550 |
124 | RPS6KC1 | 0.41574334 |
125 | RPS6KL1 | 0.41574334 |
126 | CSF1R | 0.41482184 |
127 | SGK3 | 0.40858967 |
128 | CHUK | 0.40457308 |
129 | MAP3K9 | 0.40287251 |
130 | BRAF | 0.38511299 |
131 | RPS6KA1 | 0.38182517 |
132 | MELK | 0.37933201 |
133 | MYLK | 0.37702230 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Other glycan degradation_Homo sapiens_hsa00511 | 2.49143035 |
2 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 2.22424192 |
3 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.15313318 |
4 | * Chronic myeloid leukemia_Homo sapiens_hsa05220 | 2.13260161 |
5 | * Focal adhesion_Homo sapiens_hsa04510 | 2.06297137 |
6 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.81107727 |
7 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.80752120 |
8 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.70111004 |
9 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.66220061 |
10 | Amoebiasis_Homo sapiens_hsa05146 | 1.64466791 |
11 | Bladder cancer_Homo sapiens_hsa05219 | 1.63618456 |
12 | Viral myocarditis_Homo sapiens_hsa05416 | 1.63413614 |
13 | * AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.60824040 |
14 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.55564959 |
15 | Adherens junction_Homo sapiens_hsa04520 | 1.51010942 |
16 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.50793228 |
17 | * Small cell lung cancer_Homo sapiens_hsa05222 | 1.44300306 |
18 | Prion diseases_Homo sapiens_hsa05020 | 1.43412488 |
19 | * Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.41568854 |
20 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.36354452 |
21 | * Glioma_Homo sapiens_hsa05214 | 1.34974146 |
22 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.33104990 |
23 | * Pancreatic cancer_Homo sapiens_hsa05212 | 1.32977955 |
24 | * Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.32913519 |
25 | * Platelet activation_Homo sapiens_hsa04611 | 1.29180454 |
26 | * VEGF signaling pathway_Homo sapiens_hsa04370 | 1.27865970 |
27 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.27831366 |
28 | Leishmaniasis_Homo sapiens_hsa05140 | 1.27770957 |
29 | * Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.26111279 |
30 | * Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.24137641 |
31 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.23725137 |
32 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.22668858 |
33 | * Toxoplasmosis_Homo sapiens_hsa05145 | 1.22546200 |
34 | * Endometrial cancer_Homo sapiens_hsa05213 | 1.20635189 |
35 | * mTOR signaling pathway_Homo sapiens_hsa04150 | 1.19298826 |
36 | Shigellosis_Homo sapiens_hsa05131 | 1.17004678 |
37 | * Osteoclast differentiation_Homo sapiens_hsa04380 | 1.16050536 |
38 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.15793459 |
39 | * Insulin resistance_Homo sapiens_hsa04931 | 1.14991429 |
40 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.14271238 |
41 | * ErbB signaling pathway_Homo sapiens_hsa04012 | 1.14228909 |
42 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.09209580 |
43 | * Hepatitis C_Homo sapiens_hsa05160 | 1.06638727 |
44 | * Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.05498406 |
45 | * B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.05418817 |
46 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.04372814 |
47 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.01984057 |
48 | * Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.00941270 |
49 | * Renal cell carcinoma_Homo sapiens_hsa05211 | 1.00815162 |
50 | * Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.99202567 |
51 | * Insulin signaling pathway_Homo sapiens_hsa04910 | 0.98577230 |
52 | * Colorectal cancer_Homo sapiens_hsa05210 | 0.98514602 |
53 | Salmonella infection_Homo sapiens_hsa05132 | 0.98109389 |
54 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.96763344 |
55 | Galactose metabolism_Homo sapiens_hsa00052 | 0.96367199 |
56 | * Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.96346791 |
57 | * Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.96202690 |
58 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.95991511 |
59 | * HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.95960994 |
60 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.95837770 |
61 | Endocytosis_Homo sapiens_hsa04144 | 0.94655418 |
62 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.94385390 |
63 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.93316171 |
64 | Thyroid cancer_Homo sapiens_hsa05216 | 0.93137829 |
65 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.92879298 |
66 | * Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.91665670 |
67 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.90500312 |
68 | * HTLV-I infection_Homo sapiens_hsa05166 | 0.90452989 |
69 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.90171625 |
70 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.88265766 |
71 | * Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.85934203 |
72 | * Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.85701047 |
73 | * Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.85607413 |
74 | * Apoptosis_Homo sapiens_hsa04210 | 0.84852477 |
75 | * Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.83206735 |
76 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.83057093 |
77 | Lysosome_Homo sapiens_hsa04142 | 0.83032500 |
78 | * Hepatitis B_Homo sapiens_hsa05161 | 0.81765917 |
79 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.81696276 |
80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.80550006 |
81 | Lysine degradation_Homo sapiens_hsa00310 | 0.80506361 |
82 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.79533584 |
83 | Gap junction_Homo sapiens_hsa04540 | 0.78671574 |
84 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.76239609 |
85 | * Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.76006270 |
86 | * TNF signaling pathway_Homo sapiens_hsa04668 | 0.75429830 |
87 | * AMPK signaling pathway_Homo sapiens_hsa04152 | 0.73927079 |
88 | * Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.73251759 |
89 | * Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.73103311 |
90 | * Pathways in cancer_Homo sapiens_hsa05200 | 0.73027021 |
91 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.72676571 |
92 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.72597678 |
93 | * Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.71476791 |
94 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.71308437 |
95 | * Influenza A_Homo sapiens_hsa05164 | 0.71228984 |
96 | * Tight junction_Homo sapiens_hsa04530 | 0.70544836 |
97 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.70491445 |
98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.70452296 |
99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.70249498 |
100 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.69664830 |
101 | * Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.67075739 |
102 | * Tuberculosis_Homo sapiens_hsa05152 | 0.66707371 |
103 | Pertussis_Homo sapiens_hsa05133 | 0.66211986 |
104 | * cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.62845160 |
105 | * Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.62312474 |
106 | * Prostate cancer_Homo sapiens_hsa05215 | 0.61365017 |
107 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.61313155 |
108 | Melanogenesis_Homo sapiens_hsa04916 | 0.61134164 |
109 | * Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.61083441 |
110 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.61043594 |
111 | * T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.60988355 |
112 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.59538189 |
113 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.59306544 |
114 | Legionellosis_Homo sapiens_hsa05134 | 0.58845130 |
115 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.58442628 |
116 | * FoxO signaling pathway_Homo sapiens_hsa04068 | 0.58425584 |
117 | Malaria_Homo sapiens_hsa05144 | 0.57852567 |
118 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.57240953 |
119 | Long-term potentiation_Homo sapiens_hsa04720 | 0.53948514 |
120 | Axon guidance_Homo sapiens_hsa04360 | 0.48394495 |
121 | * Measles_Homo sapiens_hsa05162 | 0.48370773 |