

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.92971254 |
| 2 | proteasome assembly (GO:0043248) | 5.11064048 |
| 3 | rRNA modification (GO:0000154) | 4.75218242 |
| 4 | response to pheromone (GO:0019236) | 4.71850804 |
| 5 | rRNA methylation (GO:0031167) | 4.41870694 |
| 6 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.38163353 |
| 7 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.24850459 |
| 8 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.24352609 |
| 9 | protein complex biogenesis (GO:0070271) | 4.22776254 |
| 10 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 4.14336760 |
| 11 | respiratory chain complex IV assembly (GO:0008535) | 4.12466348 |
| 12 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.12043312 |
| 13 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.12043312 |
| 14 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.12043312 |
| 15 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.11003685 |
| 16 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.11003685 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.10761278 |
| 18 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.06700580 |
| 19 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.06700580 |
| 20 | protein neddylation (GO:0045116) | 4.01986847 |
| 21 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.00030837 |
| 22 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.94696337 |
| 23 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.94696337 |
| 24 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.93342351 |
| 25 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.92611398 |
| 26 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.90468035 |
| 27 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.90468035 |
| 28 | NADH dehydrogenase complex assembly (GO:0010257) | 3.90468035 |
| 29 | peptidyl-histidine modification (GO:0018202) | 3.89518236 |
| 30 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.87868717 |
| 31 | maturation of 5.8S rRNA (GO:0000460) | 3.87116343 |
| 32 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.85751824 |
| 33 | negative regulation of ligase activity (GO:0051352) | 3.85751824 |
| 34 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.81914255 |
| 35 | cullin deneddylation (GO:0010388) | 3.80148323 |
| 36 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.77967545 |
| 37 | cytochrome complex assembly (GO:0017004) | 3.74133745 |
| 38 | mannosylation (GO:0097502) | 3.71329752 |
| 39 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.71168401 |
| 40 | ATP synthesis coupled proton transport (GO:0015986) | 3.63315907 |
| 41 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.63315907 |
| 42 | signal peptide processing (GO:0006465) | 3.59833393 |
| 43 | chaperone-mediated protein transport (GO:0072321) | 3.58342721 |
| 44 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.57707317 |
| 45 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.56847119 |
| 46 | protein deneddylation (GO:0000338) | 3.51852327 |
| 47 | ketone body metabolic process (GO:1902224) | 3.46661380 |
| 48 | pseudouridine synthesis (GO:0001522) | 3.43903707 |
| 49 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.43656525 |
| 50 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.42557019 |
| 51 | branched-chain amino acid catabolic process (GO:0009083) | 3.41139871 |
| 52 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.39238385 |
| 53 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.38264017 |
| 54 | positive regulation of ligase activity (GO:0051351) | 3.28591144 |
| 55 | protein targeting to mitochondrion (GO:0006626) | 3.27797015 |
| 56 | termination of RNA polymerase III transcription (GO:0006386) | 3.27255816 |
| 57 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.27255816 |
| 58 | protein maturation by protein folding (GO:0022417) | 3.27184794 |
| 59 | cellular ketone body metabolic process (GO:0046950) | 3.26570823 |
| 60 | cytidine deamination (GO:0009972) | 3.26162983 |
| 61 | cytidine metabolic process (GO:0046087) | 3.26162983 |
| 62 | cytidine catabolic process (GO:0006216) | 3.26162983 |
| 63 | respiratory electron transport chain (GO:0022904) | 3.25204192 |
| 64 | DNA double-strand break processing (GO:0000729) | 3.25196952 |
| 65 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.22922972 |
| 66 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.22918180 |
| 67 | L-methionine biosynthetic process (GO:0071265) | 3.22308466 |
| 68 | amino acid salvage (GO:0043102) | 3.22308466 |
| 69 | L-methionine salvage (GO:0071267) | 3.22308466 |
| 70 | electron transport chain (GO:0022900) | 3.18660413 |
| 71 | regulation of translational termination (GO:0006449) | 3.18609723 |
| 72 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.13471247 |
| 73 | sperm motility (GO:0030317) | 3.13018304 |
| 74 | regulation of cellular amine metabolic process (GO:0033238) | 3.08467844 |
| 75 | positive regulation of cell cycle arrest (GO:0071158) | 3.08027472 |
| 76 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.07750328 |
| 77 | establishment of protein localization to mitochondrion (GO:0072655) | 3.00067516 |
| 78 | protein localization to mitochondrion (GO:0070585) | 2.97058657 |
| 79 | response to gravity (GO:0009629) | 2.95477290 |
| 80 | platelet dense granule organization (GO:0060155) | 2.95473852 |
| 81 | protein refolding (GO:0042026) | 2.94792706 |
| 82 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.89328665 |
| 83 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.88318357 |
| 84 | protein polyglutamylation (GO:0018095) | 2.87644004 |
| 85 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.85656098 |
| 86 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.84223087 |
| 87 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.80466354 |
| 88 | tRNA processing (GO:0008033) | 2.79882568 |
| 89 | regulation of ligase activity (GO:0051340) | 2.78975354 |
| 90 | regulation of immunoglobulin secretion (GO:0051023) | 2.73485431 |
| 91 | branched-chain amino acid metabolic process (GO:0009081) | 2.71361657 |
| 92 | establishment of viral latency (GO:0019043) | 2.69998492 |
| 93 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.69963529 |
| 94 | isotype switching (GO:0045190) | 2.69963529 |
| 95 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.69963529 |
| 96 | protein-cofactor linkage (GO:0018065) | 2.69794233 |
| 97 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.69138073 |
| 98 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.68634278 |
| 99 | signal transduction in response to DNA damage (GO:0042770) | 2.65826981 |
| 100 | negative regulation of protein ubiquitination (GO:0031397) | 2.65339770 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.21206989 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.74501009 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.91779575 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.89593396 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.81031851 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.77310003 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.52775784 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.15575024 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99506115 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.91606981 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.83922943 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.65185860 |
| 13 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.58906110 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.50619265 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.45257380 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.40159094 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.38796021 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.27530235 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.20316253 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.17336856 |
| 21 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.01220372 |
| 22 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.94767927 |
| 23 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.89781199 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.88151163 |
| 25 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.74794539 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.74263178 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.71650711 |
| 28 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.70660697 |
| 29 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.68830503 |
| 30 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.68225292 |
| 31 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.67406096 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.64168794 |
| 33 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.63506353 |
| 34 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.60945233 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.60481726 |
| 36 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.58438349 |
| 37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.56262174 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.53639771 |
| 39 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.51679882 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.51104803 |
| 41 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49857395 |
| 42 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.42804189 |
| 43 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.42359943 |
| 44 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41858500 |
| 45 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.39331432 |
| 46 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.37732843 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.35815232 |
| 48 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.35095307 |
| 49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.28065806 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.24613455 |
| 51 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.21880971 |
| 52 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.20870847 |
| 53 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.18958241 |
| 54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.18682408 |
| 55 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.17941361 |
| 56 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.17916522 |
| 57 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.17107694 |
| 58 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15811345 |
| 59 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.15481885 |
| 60 | FUS_26573619_Chip-Seq_HEK293_Human | 1.13797038 |
| 61 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.12523757 |
| 62 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.12502288 |
| 63 | AR_20517297_ChIP-Seq_VCAP_Human | 1.09817112 |
| 64 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.08809622 |
| 65 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.08016266 |
| 66 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.05615608 |
| 67 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03700543 |
| 68 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03700543 |
| 69 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02914532 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01369680 |
| 71 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.01267498 |
| 72 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99357968 |
| 73 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.99065977 |
| 74 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97067980 |
| 75 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96890003 |
| 76 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96286013 |
| 77 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.96266848 |
| 78 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.95079825 |
| 79 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94886271 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.93761933 |
| 81 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.93761933 |
| 82 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92836328 |
| 83 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91767875 |
| 84 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91671648 |
| 85 | EWS_26573619_Chip-Seq_HEK293_Human | 0.91596294 |
| 86 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91265441 |
| 87 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.90925177 |
| 88 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.90515525 |
| 89 | NCOR_22424771_ChIP-Seq_293T_Human | 0.89845451 |
| 90 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.89407802 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89102095 |
| 92 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.88844694 |
| 93 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.88067047 |
| 94 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.87952957 |
| 95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.87462295 |
| 96 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.87248747 |
| 97 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.86328176 |
| 98 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.85725879 |
| 99 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.84859604 |
| 100 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.84506987 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 3.65477012 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 3.34080764 |
| 3 | MP0008875_abnormal_xenobiotic_pharmacok | 2.92572139 |
| 4 | MP0005410_abnormal_fertilization | 2.81523355 |
| 5 | MP0006036_abnormal_mitochondrial_physio | 2.68470111 |
| 6 | MP0008058_abnormal_DNA_repair | 2.54301561 |
| 7 | MP0003646_muscle_fatigue | 2.32936103 |
| 8 | MP0005671_abnormal_response_to | 2.30130875 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.29938295 |
| 10 | MP0006035_abnormal_mitochondrial_morpho | 2.29370728 |
| 11 | MP0005075_abnormal_melanosome_morpholog | 2.28218499 |
| 12 | MP0001873_stomach_inflammation | 2.24309085 |
| 13 | MP0003718_maternal_effect | 2.23160887 |
| 14 | MP0000569_abnormal_digit_pigmentation | 2.21225321 |
| 15 | MP0000015_abnormal_ear_pigmentation | 2.12745150 |
| 16 | MP0009785_altered_susceptibility_to | 2.02518038 |
| 17 | MP0003786_premature_aging | 2.00455357 |
| 18 | MP0003186_abnormal_redox_activity | 1.97292692 |
| 19 | MP0002095_abnormal_skin_pigmentation | 1.96430393 |
| 20 | MP0005387_immune_system_phenotype | 1.95637245 |
| 21 | MP0001790_abnormal_immune_system | 1.95637245 |
| 22 | MP0002102_abnormal_ear_morphology | 1.88935568 |
| 23 | MP0008872_abnormal_physiological_respon | 1.88785967 |
| 24 | MP0008877_abnormal_DNA_methylation | 1.84385970 |
| 25 | MP0000749_muscle_degeneration | 1.82752587 |
| 26 | MP0005084_abnormal_gallbladder_morpholo | 1.69861612 |
| 27 | MP0003950_abnormal_plasma_membrane | 1.66815595 |
| 28 | MP0003195_calcinosis | 1.66752574 |
| 29 | MP0001661_extended_life_span | 1.65492915 |
| 30 | MP0005408_hypopigmentation | 1.63261353 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.62080465 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.60404428 |
| 33 | MP0002837_dystrophic_cardiac_calcinosis | 1.54872196 |
| 34 | MP0001905_abnormal_dopamine_level | 1.48783017 |
| 35 | MP0008775_abnormal_heart_ventricle | 1.44966498 |
| 36 | MP0004145_abnormal_muscle_electrophysio | 1.41403007 |
| 37 | MP0001764_abnormal_homeostasis | 1.38578814 |
| 38 | MP0002277_abnormal_respiratory_mucosa | 1.36267829 |
| 39 | MP0001529_abnormal_vocalization | 1.36183353 |
| 40 | MP0005253_abnormal_eye_physiology | 1.33791659 |
| 41 | MP0005083_abnormal_biliary_tract | 1.32711038 |
| 42 | MP0010094_abnormal_chromosome_stability | 1.31979510 |
| 43 | MP0003878_abnormal_ear_physiology | 1.31793132 |
| 44 | MP0005377_hearing/vestibular/ear_phenot | 1.31793132 |
| 45 | MP0002166_altered_tumor_susceptibility | 1.28047508 |
| 46 | MP0009333_abnormal_splenocyte_physiolog | 1.27870208 |
| 47 | MP0002006_tumorigenesis | 1.26381589 |
| 48 | MP0002876_abnormal_thyroid_physiology | 1.24399254 |
| 49 | MP0001800_abnormal_humoral_immune | 1.24071676 |
| 50 | MP0000685_abnormal_immune_system | 1.19903545 |
| 51 | MP0001929_abnormal_gametogenesis | 1.19105771 |
| 52 | MP0006054_spinal_hemorrhage | 1.17980376 |
| 53 | MP0005165_increased_susceptibility_to | 1.17642249 |
| 54 | MP0003693_abnormal_embryo_hatching | 1.16981120 |
| 55 | MP0002933_joint_inflammation | 1.11116734 |
| 56 | MP0006072_abnormal_retinal_apoptosis | 1.10582791 |
| 57 | MP0009046_muscle_twitch | 1.10232708 |
| 58 | MP0003436_decreased_susceptibility_to | 1.09267741 |
| 59 | MP0004147_increased_porphyrin_level | 1.08548192 |
| 60 | MP0002138_abnormal_hepatobiliary_system | 1.05569714 |
| 61 | MP0005000_abnormal_immune_tolerance | 1.02839558 |
| 62 | MP0000358_abnormal_cell_content/ | 1.01135051 |
| 63 | MP0003698_abnormal_male_reproductive | 0.99823780 |
| 64 | MP0004142_abnormal_muscle_tone | 0.99452218 |
| 65 | MP0004957_abnormal_blastocyst_morpholog | 0.98535245 |
| 66 | MP0002723_abnormal_immune_serum | 0.97957147 |
| 67 | MP0005174_abnormal_tail_pigmentation | 0.95307535 |
| 68 | MP0001968_abnormal_touch/_nociception | 0.93633611 |
| 69 | MP0005636_abnormal_mineral_homeostasis | 0.92406872 |
| 70 | MP0005310_abnormal_salivary_gland | 0.91479821 |
| 71 | MP0003866_abnormal_defecation | 0.89965918 |
| 72 | MP0002282_abnormal_trachea_morphology | 0.87346672 |
| 73 | MP0010155_abnormal_intestine_physiology | 0.85988961 |
| 74 | MP0005171_absent_coat_pigmentation | 0.81412262 |
| 75 | MP0001853_heart_inflammation | 0.81370561 |
| 76 | MP0002452_abnormal_antigen_presenting | 0.80773397 |
| 77 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.78677701 |
| 78 | MP0002736_abnormal_nociception_after | 0.78072553 |
| 79 | MP0009745_abnormal_behavioral_response | 0.78065996 |
| 80 | MP0002090_abnormal_vision | 0.77726663 |
| 81 | MP0002210_abnormal_sex_determination | 0.76944542 |
| 82 | MP0001501_abnormal_sleep_pattern | 0.76837652 |
| 83 | MP0002822_catalepsy | 0.76376295 |
| 84 | MP0003880_abnormal_central_pattern | 0.76290337 |
| 85 | MP0002272_abnormal_nervous_system | 0.76112116 |
| 86 | MP0005332_abnormal_amino_acid | 0.76031903 |
| 87 | MP0009697_abnormal_copulation | 0.75810101 |
| 88 | MP0008007_abnormal_cellular_replicative | 0.75453802 |
| 89 | MP0002693_abnormal_pancreas_physiology | 0.75448197 |
| 90 | MP0000371_diluted_coat_color | 0.75250476 |
| 91 | MP0000653_abnormal_sex_gland | 0.72870688 |
| 92 | MP0008469_abnormal_protein_level | 0.72831629 |
| 93 | MP0003011_delayed_dark_adaptation | 0.72728104 |
| 94 | MP0002420_abnormal_adaptive_immunity | 0.72201150 |
| 95 | MP0001819_abnormal_immune_cell | 0.72109635 |
| 96 | MP0000647_abnormal_sebaceous_gland | 0.71757970 |
| 97 | MP0005319_abnormal_enzyme/_coenzyme | 0.70837335 |
| 98 | MP0001324_abnormal_eye_pigmentation | 0.70799036 |
| 99 | MP0004484_altered_response_of | 0.70240654 |
| 100 | MP0008873_increased_physiological_sensi | 0.69910368 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.84229644 |
| 2 | Increased CSF lactate (HP:0002490) | 4.76862742 |
| 3 | Hepatocellular necrosis (HP:0001404) | 4.70429044 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.69109952 |
| 5 | Renal Fanconi syndrome (HP:0001994) | 4.63336791 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.56984454 |
| 7 | Hepatic necrosis (HP:0002605) | 4.35704752 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.16231983 |
| 9 | 3-Methylglutaconic aciduria (HP:0003535) | 4.15178161 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 4.11532283 |
| 11 | Acute encephalopathy (HP:0006846) | 4.07594435 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.99770371 |
| 13 | Increased serum lactate (HP:0002151) | 3.53639690 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.37898587 |
| 15 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.35320024 |
| 16 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.33398546 |
| 17 | Large for gestational age (HP:0001520) | 3.19509992 |
| 18 | Cerebral edema (HP:0002181) | 3.18290836 |
| 19 | Congenital stationary night blindness (HP:0007642) | 3.14904388 |
| 20 | Lactic acidosis (HP:0003128) | 3.14066497 |
| 21 | Exertional dyspnea (HP:0002875) | 3.11993733 |
| 22 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.04758645 |
| 23 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.04758645 |
| 24 | Increased serum pyruvate (HP:0003542) | 2.87055651 |
| 25 | Abnormality of glycolysis (HP:0004366) | 2.85732725 |
| 26 | Cerebral hypomyelination (HP:0006808) | 2.83064317 |
| 27 | Stomatitis (HP:0010280) | 2.72805959 |
| 28 | Respiratory difficulties (HP:0002880) | 2.71054513 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.70696114 |
| 30 | Respiratory failure (HP:0002878) | 2.65452360 |
| 31 | Adrenal hypoplasia (HP:0000835) | 2.65369732 |
| 32 | Optic disc pallor (HP:0000543) | 2.63536302 |
| 33 | IgG deficiency (HP:0004315) | 2.63268483 |
| 34 | Exercise intolerance (HP:0003546) | 2.61724365 |
| 35 | Abnormality of renal resorption (HP:0011038) | 2.59778650 |
| 36 | Generalized aminoaciduria (HP:0002909) | 2.57418262 |
| 37 | Type I transferrin isoform profile (HP:0003642) | 2.57403475 |
| 38 | Methylmalonic aciduria (HP:0012120) | 2.51370574 |
| 39 | Lethargy (HP:0001254) | 2.50094623 |
| 40 | Abnormality of urine glucose concentration (HP:0011016) | 2.46452952 |
| 41 | Glycosuria (HP:0003076) | 2.46452952 |
| 42 | CNS demyelination (HP:0007305) | 2.43780835 |
| 43 | Congenital, generalized hypertrichosis (HP:0004540) | 2.33692328 |
| 44 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.30587092 |
| 45 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.30587092 |
| 46 | Abnormal protein glycosylation (HP:0012346) | 2.30587092 |
| 47 | Abnormal glycosylation (HP:0012345) | 2.30587092 |
| 48 | Cholecystitis (HP:0001082) | 2.30173438 |
| 49 | Abnormal gallbladder physiology (HP:0012438) | 2.30173438 |
| 50 | Emotional lability (HP:0000712) | 2.28500384 |
| 51 | Pancreatic cysts (HP:0001737) | 2.25367889 |
| 52 | Hypothermia (HP:0002045) | 2.25005343 |
| 53 | Nephronophthisis (HP:0000090) | 2.24680025 |
| 54 | Abnormality of midbrain morphology (HP:0002418) | 2.24558635 |
| 55 | Molar tooth sign on MRI (HP:0002419) | 2.24558635 |
| 56 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.24552387 |
| 57 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.22857935 |
| 58 | Progressive inability to walk (HP:0002505) | 2.19825212 |
| 59 | Hypoplasia of the fovea (HP:0007750) | 2.13250234 |
| 60 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.13250234 |
| 61 | Abnormality of the renal cortex (HP:0011035) | 2.10642356 |
| 62 | Leukodystrophy (HP:0002415) | 2.10288661 |
| 63 | Abnormal spermatogenesis (HP:0008669) | 2.09867278 |
| 64 | Abnormality of alanine metabolism (HP:0010916) | 2.09190104 |
| 65 | Hyperalaninemia (HP:0003348) | 2.09190104 |
| 66 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.09190104 |
| 67 | Aplastic anemia (HP:0001915) | 2.08854187 |
| 68 | Methylmalonic acidemia (HP:0002912) | 2.07786737 |
| 69 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.06488724 |
| 70 | CNS hypomyelination (HP:0003429) | 2.05932425 |
| 71 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.04138428 |
| 72 | Abnormality of the renal medulla (HP:0100957) | 2.01794299 |
| 73 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.01607706 |
| 74 | Inability to walk (HP:0002540) | 1.98828248 |
| 75 | Type 2 muscle fiber atrophy (HP:0003554) | 1.97681537 |
| 76 | Abnormality of macular pigmentation (HP:0008002) | 1.95739346 |
| 77 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.93042476 |
| 78 | Oral leukoplakia (HP:0002745) | 1.93014672 |
| 79 | Renal cortical cysts (HP:0000803) | 1.90734576 |
| 80 | Severe visual impairment (HP:0001141) | 1.90637562 |
| 81 | Abnormality of T cell physiology (HP:0011840) | 1.89492972 |
| 82 | IgA deficiency (HP:0002720) | 1.87783341 |
| 83 | Attenuation of retinal blood vessels (HP:0007843) | 1.87375097 |
| 84 | Progressive microcephaly (HP:0000253) | 1.85994487 |
| 85 | Abnormality of the pons (HP:0007361) | 1.83998928 |
| 86 | Blindness (HP:0000618) | 1.80038203 |
| 87 | Abnormality of the fovea (HP:0000493) | 1.76023048 |
| 88 | Muscle fiber atrophy (HP:0100295) | 1.75333358 |
| 89 | Polydipsia (HP:0001959) | 1.73871980 |
| 90 | Abnormal drinking behavior (HP:0030082) | 1.73871980 |
| 91 | Hyperphosphaturia (HP:0003109) | 1.73393605 |
| 92 | Polyuria (HP:0000103) | 1.72093439 |
| 93 | Median cleft lip (HP:0000161) | 1.72072624 |
| 94 | X-linked dominant inheritance (HP:0001423) | 1.70883718 |
| 95 | Opisthotonus (HP:0002179) | 1.70861197 |
| 96 | Hypoplasia of the uterus (HP:0000013) | 1.70631545 |
| 97 | Abnormality of methionine metabolism (HP:0010901) | 1.70520214 |
| 98 | Pancytopenia (HP:0001876) | 1.69353127 |
| 99 | Sparse eyelashes (HP:0000653) | 1.68354313 |
| 100 | Amniotic constriction ring (HP:0009775) | 1.67944545 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.81346117 |
| 2 | BCKDK | 3.18984866 |
| 3 | TXK | 2.99490569 |
| 4 | EIF2AK1 | 2.95886115 |
| 5 | TSSK6 | 2.66827671 |
| 6 | MST4 | 2.54785562 |
| 7 | NEK1 | 2.45242671 |
| 8 | EIF2AK3 | 2.38763495 |
| 9 | NUAK1 | 2.29196414 |
| 10 | MAP3K12 | 2.25148030 |
| 11 | VRK1 | 2.15668228 |
| 12 | PHKG2 | 2.14626128 |
| 13 | PHKG1 | 2.14626128 |
| 14 | TLK1 | 2.10492660 |
| 15 | PDK2 | 2.05741957 |
| 16 | TESK1 | 1.99833755 |
| 17 | WNK4 | 1.97775762 |
| 18 | MAP4K2 | 1.91823514 |
| 19 | BUB1 | 1.88412762 |
| 20 | ZAK | 1.77152786 |
| 21 | NME2 | 1.71640178 |
| 22 | MAPKAPK5 | 1.61648407 |
| 23 | LIMK1 | 1.61354791 |
| 24 | PLK3 | 1.60738725 |
| 25 | FRK | 1.60317712 |
| 26 | TAOK3 | 1.54237745 |
| 27 | DAPK1 | 1.50643146 |
| 28 | STK16 | 1.50175863 |
| 29 | SRPK1 | 1.49048370 |
| 30 | TRIM28 | 1.45424033 |
| 31 | PLK2 | 1.27520711 |
| 32 | CSNK1G3 | 1.25227254 |
| 33 | MAPKAPK3 | 1.22118998 |
| 34 | STK39 | 1.21371192 |
| 35 | GRK5 | 1.19551582 |
| 36 | ADRBK2 | 1.18663530 |
| 37 | ARAF | 1.16611320 |
| 38 | INSRR | 1.16048347 |
| 39 | PINK1 | 1.15795370 |
| 40 | MAP2K6 | 1.14621703 |
| 41 | CCNB1 | 1.14456820 |
| 42 | STK38L | 1.10972629 |
| 43 | OXSR1 | 1.06326763 |
| 44 | CSNK1G2 | 1.06080358 |
| 45 | GRK1 | 1.03591766 |
| 46 | CSNK1G1 | 1.01427238 |
| 47 | CSNK1A1L | 1.01217464 |
| 48 | EIF2AK2 | 0.96081707 |
| 49 | MYLK | 0.95461227 |
| 50 | TIE1 | 0.92906155 |
| 51 | BMPR1B | 0.88023589 |
| 52 | TAF1 | 0.87441326 |
| 53 | PTK2B | 0.83404724 |
| 54 | PLK4 | 0.82810662 |
| 55 | IKBKB | 0.81590141 |
| 56 | TESK2 | 0.75872392 |
| 57 | PBK | 0.75643057 |
| 58 | ACVR1B | 0.71485604 |
| 59 | NME1 | 0.71298508 |
| 60 | OBSCN | 0.65177935 |
| 61 | PIM2 | 0.62934703 |
| 62 | WNK3 | 0.61673381 |
| 63 | CAMKK2 | 0.56646933 |
| 64 | KDR | 0.51797884 |
| 65 | ILK | 0.48266940 |
| 66 | WEE1 | 0.45409718 |
| 67 | ATR | 0.45013774 |
| 68 | DAPK2 | 0.43548218 |
| 69 | PRKD3 | 0.42971170 |
| 70 | DAPK3 | 0.42716453 |
| 71 | RPS6KA5 | 0.42601149 |
| 72 | ABL2 | 0.42528385 |
| 73 | TEC | 0.42456600 |
| 74 | LMTK2 | 0.40609852 |
| 75 | PRKG2 | 0.40478111 |
| 76 | ADRBK1 | 0.40029265 |
| 77 | PLK1 | 0.38588794 |
| 78 | CSF1R | 0.37618810 |
| 79 | MAP2K7 | 0.36504013 |
| 80 | ERBB3 | 0.36406871 |
| 81 | PAK4 | 0.34111394 |
| 82 | TTK | 0.33784124 |
| 83 | CSNK2A1 | 0.33328546 |
| 84 | JAK3 | 0.33036371 |
| 85 | PRKCQ | 0.31011846 |
| 86 | MAP3K13 | 0.30914321 |
| 87 | ITK | 0.30416048 |
| 88 | PIK3CG | 0.29574727 |
| 89 | PRKCE | 0.29562886 |
| 90 | PRKCG | 0.28314259 |
| 91 | CSNK2A2 | 0.28059318 |
| 92 | MAPK13 | 0.27881894 |
| 93 | PRKCI | 0.26915720 |
| 94 | CDK7 | 0.26166882 |
| 95 | SYK | 0.24830996 |
| 96 | ERBB4 | 0.24766621 |
| 97 | FLT3 | 0.23960226 |
| 98 | STK38 | 0.23867068 |
| 99 | MOS | 0.22689152 |
| 100 | PRKG1 | 0.22655255 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.60974415 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.36307482 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 2.85323892 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.81563571 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.57141012 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.33189045 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.31789120 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.08646987 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.00221486 |
| 10 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.97849263 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 1.93721539 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.87206470 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.79223631 |
| 14 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.77908249 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.75750320 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.75083841 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.56196287 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.55172538 |
| 19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.51040944 |
| 20 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.50910403 |
| 21 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.49511961 |
| 22 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.49246458 |
| 23 | Ribosome_Homo sapiens_hsa03010 | 1.42757958 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.42667367 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.40111353 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.39926667 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.37709222 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.33839236 |
| 29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.31801244 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.30898623 |
| 31 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30075043 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.27110134 |
| 33 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.25630130 |
| 34 | DNA replication_Homo sapiens_hsa03030 | 1.25379117 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 1.23987069 |
| 36 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.21683397 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.18510444 |
| 38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.18194122 |
| 39 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17580133 |
| 40 | RNA transport_Homo sapiens_hsa03013 | 1.12944532 |
| 41 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.10783711 |
| 42 | Base excision repair_Homo sapiens_hsa03410 | 1.08758526 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.08344271 |
| 44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.06242082 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.05937023 |
| 46 | Phototransduction_Homo sapiens_hsa04744 | 1.03245895 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.02367822 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.00375696 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.99773579 |
| 50 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.98775045 |
| 51 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.95431820 |
| 52 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.94729750 |
| 53 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.94626332 |
| 54 | Carbon metabolism_Homo sapiens_hsa01200 | 0.92868971 |
| 55 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.92774483 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.90734518 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.89378907 |
| 58 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.87520559 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.84254259 |
| 60 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.83362013 |
| 61 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.82866908 |
| 62 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.82277019 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.81611724 |
| 64 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80884319 |
| 65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78620531 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.75970698 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.75337243 |
| 68 | Sulfur relay system_Homo sapiens_hsa04122 | 0.74640387 |
| 69 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.74171486 |
| 70 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.67036227 |
| 71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.66632172 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64298869 |
| 73 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.62836843 |
| 74 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.62387125 |
| 75 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.61688771 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58605442 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.57089076 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.56879827 |
| 79 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.54363334 |
| 80 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.51177917 |
| 81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48687278 |
| 82 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.48013960 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.47772339 |
| 84 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47226129 |
| 85 | Salivary secretion_Homo sapiens_hsa04970 | 0.42100569 |
| 86 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38696171 |
| 87 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.37811806 |
| 88 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.37420893 |
| 89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.36824763 |
| 90 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.36335662 |
| 91 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.34846246 |
| 92 | Measles_Homo sapiens_hsa05162 | 0.34840230 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.34567081 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34143322 |
| 95 | Legionellosis_Homo sapiens_hsa05134 | 0.34025517 |
| 96 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.33234248 |
| 97 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.26843266 |
| 98 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.26654902 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26502890 |
| 100 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26481771 |

