

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of female receptivity (GO:0045924) | 7.90975305 |
| 2 | female mating behavior (GO:0060180) | 6.83628967 |
| 3 | relaxation of smooth muscle (GO:0044557) | 5.80629203 |
| 4 | meiotic chromosome segregation (GO:0045132) | 5.01466737 |
| 5 | behavioral response to nicotine (GO:0035095) | 4.45591441 |
| 6 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 4.36321289 |
| 7 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.22912675 |
| 8 | indolalkylamine metabolic process (GO:0006586) | 4.10438760 |
| 9 | DNA double-strand break processing (GO:0000729) | 3.95518153 |
| 10 | protein-chromophore linkage (GO:0018298) | 3.84756442 |
| 11 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.75223887 |
| 12 | deoxyribonucleotide catabolic process (GO:0009264) | 3.74052026 |
| 13 | amino acid salvage (GO:0043102) | 3.70135669 |
| 14 | L-methionine salvage (GO:0071267) | 3.70135669 |
| 15 | L-methionine biosynthetic process (GO:0071265) | 3.70135669 |
| 16 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.66742927 |
| 17 | detection of light stimulus involved in visual perception (GO:0050908) | 3.63084368 |
| 18 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.63084368 |
| 19 | multicellular organism reproduction (GO:0032504) | 3.62194385 |
| 20 | indole-containing compound catabolic process (GO:0042436) | 3.51091673 |
| 21 | indolalkylamine catabolic process (GO:0046218) | 3.51091673 |
| 22 | tryptophan catabolic process (GO:0006569) | 3.51091673 |
| 23 | coenzyme catabolic process (GO:0009109) | 3.50523333 |
| 24 | high-density lipoprotein particle remodeling (GO:0034375) | 3.43268201 |
| 25 | behavioral response to ethanol (GO:0048149) | 3.40961382 |
| 26 | methionine biosynthetic process (GO:0009086) | 3.39090336 |
| 27 | protein localization to cilium (GO:0061512) | 3.38912698 |
| 28 | deoxyribose phosphate catabolic process (GO:0046386) | 3.37711652 |
| 29 | neural tube formation (GO:0001841) | 3.34039866 |
| 30 | response to pheromone (GO:0019236) | 3.33246849 |
| 31 | tryptophan metabolic process (GO:0006568) | 3.33007704 |
| 32 | sperm motility (GO:0030317) | 3.32979282 |
| 33 | otic vesicle formation (GO:0030916) | 3.32442100 |
| 34 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.32393872 |
| 35 | dopamine transport (GO:0015872) | 3.32365709 |
| 36 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.31465931 |
| 37 | tachykinin receptor signaling pathway (GO:0007217) | 3.30367353 |
| 38 | transmission of nerve impulse (GO:0019226) | 3.24761473 |
| 39 | methionine metabolic process (GO:0006555) | 3.22400903 |
| 40 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.20140534 |
| 41 | UMP metabolic process (GO:0046049) | 3.20140534 |
| 42 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.20140534 |
| 43 | UMP biosynthetic process (GO:0006222) | 3.20140534 |
| 44 | reverse cholesterol transport (GO:0043691) | 3.19259483 |
| 45 | multicellular organismal reproductive behavior (GO:0033057) | 3.16660933 |
| 46 | long term synaptic depression (GO:0060292) | 3.11425723 |
| 47 | cardiolipin metabolic process (GO:0032048) | 3.08300320 |
| 48 | regulation of hippo signaling (GO:0035330) | 3.03986412 |
| 49 | xenobiotic catabolic process (GO:0042178) | 3.03767053 |
| 50 | adenosine metabolic process (GO:0046085) | 2.98123285 |
| 51 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.96862042 |
| 52 | negative regulation of lipase activity (GO:0060192) | 2.95034444 |
| 53 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.94773180 |
| 54 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.94773180 |
| 55 | ectoderm development (GO:0007398) | 2.94305666 |
| 56 | amine catabolic process (GO:0009310) | 2.90497821 |
| 57 | cellular biogenic amine catabolic process (GO:0042402) | 2.90497821 |
| 58 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 2.89429875 |
| 59 | somite rostral/caudal axis specification (GO:0032525) | 2.88042021 |
| 60 | mast cell activation involved in immune response (GO:0002279) | 2.85366096 |
| 61 | mast cell degranulation (GO:0043303) | 2.85366096 |
| 62 | sulfation (GO:0051923) | 2.81991540 |
| 63 | photoreceptor cell maintenance (GO:0045494) | 2.80118321 |
| 64 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.76914893 |
| 65 | auditory receptor cell stereocilium organization (GO:0060088) | 2.74847195 |
| 66 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.74527377 |
| 67 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.73653106 |
| 68 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.72478310 |
| 69 | S-adenosylmethionine metabolic process (GO:0046500) | 2.72297368 |
| 70 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 2.72267465 |
| 71 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 2.71543163 |
| 72 | limb bud formation (GO:0060174) | 2.71106789 |
| 73 | relaxation of muscle (GO:0090075) | 2.65620837 |
| 74 | male meiosis (GO:0007140) | 2.65455659 |
| 75 | nitric oxide mediated signal transduction (GO:0007263) | 2.64955006 |
| 76 | neuronal action potential (GO:0019228) | 2.63006890 |
| 77 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 2.62970817 |
| 78 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.61586986 |
| 79 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.61107121 |
| 80 | axoneme assembly (GO:0035082) | 2.60125134 |
| 81 | regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 2.59325122 |
| 82 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.58180179 |
| 83 | regulation of DNA-templated transcription, initiation (GO:2000142) | 2.57705449 |
| 84 | indole-containing compound metabolic process (GO:0042430) | 2.57142273 |
| 85 | aspartate family amino acid catabolic process (GO:0009068) | 2.56922902 |
| 86 | regulation of megakaryocyte differentiation (GO:0045652) | 2.56681591 |
| 87 | cilium morphogenesis (GO:0060271) | 2.54994777 |
| 88 | histone H3-K9 methylation (GO:0051567) | 2.53405742 |
| 89 | positive regulation of male gonad development (GO:2000020) | 2.52695037 |
| 90 | amine biosynthetic process (GO:0009309) | 2.52389297 |
| 91 | base-excision repair, AP site formation (GO:0006285) | 2.51825149 |
| 92 | left/right axis specification (GO:0070986) | 2.51292212 |
| 93 | double-strand break repair via homologous recombination (GO:0000724) | 2.50132068 |
| 94 | rhodopsin mediated signaling pathway (GO:0016056) | 2.49423885 |
| 95 | intraciliary transport (GO:0042073) | 2.49283630 |
| 96 | piRNA metabolic process (GO:0034587) | 2.48379960 |
| 97 | kynurenine metabolic process (GO:0070189) | 2.48204486 |
| 98 | regulation of female gonad development (GO:2000194) | 2.47918607 |
| 99 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.47724768 |
| 100 | recombinational repair (GO:0000725) | 2.46499898 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.03410347 |
| 2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.47201883 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.22108725 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 2.55628611 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.54825457 |
| 6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.43448704 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.39673866 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.37461002 |
| 9 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.32414587 |
| 10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.21061628 |
| 11 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.17490460 |
| 12 | * P300_19829295_ChIP-Seq_ESCs_Human | 2.16528803 |
| 13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.13034247 |
| 14 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.12359073 |
| 15 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.07411462 |
| 16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.05012174 |
| 17 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.99669103 |
| 18 | EWS_26573619_Chip-Seq_HEK293_Human | 1.99642150 |
| 19 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.97293312 |
| 20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.96272892 |
| 21 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.94011494 |
| 22 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.90475550 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.88770924 |
| 24 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.86757952 |
| 25 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.83052619 |
| 26 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.79404932 |
| 27 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.79404932 |
| 28 | STAT3_23295773_ChIP-Seq_U87_Human | 1.78587920 |
| 29 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.77443286 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.76856237 |
| 31 | TCF4_23295773_ChIP-Seq_U87_Human | 1.69011098 |
| 32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.67917974 |
| 33 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.64159451 |
| 34 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.62051584 |
| 35 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.59060703 |
| 36 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.59060703 |
| 37 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.58918568 |
| 38 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.55592641 |
| 39 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.55592641 |
| 40 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.55382346 |
| 41 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.47556250 |
| 42 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.46390345 |
| 43 | AR_25329375_ChIP-Seq_VCAP_Human | 1.46129353 |
| 44 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.46022149 |
| 45 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.43257957 |
| 46 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42543489 |
| 47 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.42362412 |
| 48 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.33956032 |
| 49 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.31424238 |
| 50 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.31047692 |
| 51 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.30901827 |
| 52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30857829 |
| 53 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.29437260 |
| 54 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.28291735 |
| 55 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.28256243 |
| 56 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.28088456 |
| 57 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.27192154 |
| 58 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.26551079 |
| 59 | * PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.26313114 |
| 60 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.24638704 |
| 61 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.24013349 |
| 62 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.23433665 |
| 63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.20462203 |
| 64 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.19880611 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.19880611 |
| 66 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.19212152 |
| 67 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.18100978 |
| 68 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.17328566 |
| 69 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.16508578 |
| 70 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.15958933 |
| 71 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.15438087 |
| 72 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.14919232 |
| 73 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.14449694 |
| 74 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.13974135 |
| 75 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12054698 |
| 76 | GATA3_26560356_Chip-Seq_TH2_Human | 1.11388783 |
| 77 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.09293437 |
| 78 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.09048014 |
| 79 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.08783816 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 1.08260797 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.07950399 |
| 82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.06164167 |
| 83 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03719820 |
| 84 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.03107335 |
| 85 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.02112872 |
| 86 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.01379933 |
| 87 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.01344994 |
| 88 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.00926348 |
| 89 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00844747 |
| 90 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.98803322 |
| 91 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.97130649 |
| 92 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95859921 |
| 93 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.95082883 |
| 94 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.94020793 |
| 95 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.93972908 |
| 96 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.92811451 |
| 97 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.92002812 |
| 98 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.92002812 |
| 99 | KDM2B_26808549_Chip-Seq_REH_Human | 0.91862559 |
| 100 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.90978477 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 5.15379546 |
| 2 | MP0009780_abnormal_chondrocyte_physiolo | 4.43460969 |
| 3 | MP0009697_abnormal_copulation | 4.24239669 |
| 4 | MP0002132_abnormal_respiratory_system | 3.53246733 |
| 5 | MP0000372_irregular_coat_pigmentation | 3.15841868 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.74878572 |
| 7 | MP0008004_abnormal_stomach_pH | 2.72292767 |
| 8 | MP0005551_abnormal_eye_electrophysiolog | 2.69270753 |
| 9 | MP0006276_abnormal_autonomic_nervous | 2.67937428 |
| 10 | MP0004043_abnormal_pH_regulation | 2.58085739 |
| 11 | MP0003879_abnormal_hair_cell | 2.49231122 |
| 12 | MP0005410_abnormal_fertilization | 2.38341273 |
| 13 | MP0002102_abnormal_ear_morphology | 2.36991933 |
| 14 | MP0002163_abnormal_gland_morphology | 2.36887389 |
| 15 | MP0008057_abnormal_DNA_replication | 2.29604444 |
| 16 | MP0006054_spinal_hemorrhage | 2.15139742 |
| 17 | MP0005646_abnormal_pituitary_gland | 2.15074939 |
| 18 | MP0001984_abnormal_olfaction | 2.13676140 |
| 19 | MP0008877_abnormal_DNA_methylation | 2.11156974 |
| 20 | MP0002090_abnormal_vision | 2.00950959 |
| 21 | MP0005464_abnormal_platelet_physiology | 1.92376955 |
| 22 | MP0005253_abnormal_eye_physiology | 1.86361684 |
| 23 | MP0001986_abnormal_taste_sensitivity | 1.83761459 |
| 24 | MP0005187_abnormal_penis_morphology | 1.78697896 |
| 25 | MP0004381_abnormal_hair_follicle | 1.70456587 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.61800745 |
| 27 | MP0005360_urolithiasis | 1.56947323 |
| 28 | MP0005075_abnormal_melanosome_morpholog | 1.46931030 |
| 29 | MP0002736_abnormal_nociception_after | 1.46188067 |
| 30 | MP0005171_absent_coat_pigmentation | 1.45690503 |
| 31 | MP0000383_abnormal_hair_follicle | 1.44512980 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.39533112 |
| 33 | MP0008775_abnormal_heart_ventricle | 1.39424908 |
| 34 | MP0003123_paternal_imprinting | 1.37335987 |
| 35 | MP0009046_muscle_twitch | 1.33843526 |
| 36 | MP0004885_abnormal_endolymph | 1.32102593 |
| 37 | MP0001501_abnormal_sleep_pattern | 1.30418533 |
| 38 | MP0008872_abnormal_physiological_respon | 1.22457187 |
| 39 | MP0005379_endocrine/exocrine_gland_phen | 1.21279935 |
| 40 | MP0000230_abnormal_systemic_arterial | 1.20768543 |
| 41 | MP0003878_abnormal_ear_physiology | 1.18574375 |
| 42 | MP0005377_hearing/vestibular/ear_phenot | 1.18574375 |
| 43 | MP0002653_abnormal_ependyma_morphology | 1.15439834 |
| 44 | MP0010329_abnormal_lipoprotein_level | 1.13989032 |
| 45 | MP0008875_abnormal_xenobiotic_pharmacok | 1.12825969 |
| 46 | MP0006035_abnormal_mitochondrial_morpho | 1.09407802 |
| 47 | MP0004085_abnormal_heartbeat | 1.08555238 |
| 48 | MP0002876_abnormal_thyroid_physiology | 1.07675558 |
| 49 | MP0006292_abnormal_olfactory_placode | 1.05581741 |
| 50 | MP0003698_abnormal_male_reproductive | 1.05321956 |
| 51 | MP0002160_abnormal_reproductive_system | 1.01814679 |
| 52 | MP0000631_abnormal_neuroendocrine_gland | 1.01013243 |
| 53 | MP0000647_abnormal_sebaceous_gland | 1.00935751 |
| 54 | MP0003121_genomic_imprinting | 0.99514047 |
| 55 | MP0005167_abnormal_blood-brain_barrier | 0.98454370 |
| 56 | MP0001963_abnormal_hearing_physiology | 0.96467398 |
| 57 | MP0003787_abnormal_imprinting | 0.94176131 |
| 58 | MP0003718_maternal_effect | 0.93030401 |
| 59 | MP0004147_increased_porphyrin_level | 0.91936349 |
| 60 | MP0001756_abnormal_urination | 0.91707845 |
| 61 | MP0002938_white_spotting | 0.89615912 |
| 62 | MP0001486_abnormal_startle_reflex | 0.87318998 |
| 63 | MP0000465_gastrointestinal_hemorrhage | 0.84602322 |
| 64 | MP0000538_abnormal_urinary_bladder | 0.84044826 |
| 65 | MP0003195_calcinosis | 0.81089052 |
| 66 | MP0001293_anophthalmia | 0.80814747 |
| 67 | MP0002272_abnormal_nervous_system | 0.80437380 |
| 68 | MP0010030_abnormal_orbit_morphology | 0.80268249 |
| 69 | MP0005391_vision/eye_phenotype | 0.80095783 |
| 70 | MP0009745_abnormal_behavioral_response | 0.79343750 |
| 71 | MP0003638_abnormal_response/metabolism_ | 0.76943438 |
| 72 | MP0010386_abnormal_urinary_bladder | 0.76551121 |
| 73 | MP0003119_abnormal_digestive_system | 0.74553845 |
| 74 | MP0005174_abnormal_tail_pigmentation | 0.73023853 |
| 75 | MP0001929_abnormal_gametogenesis | 0.72217957 |
| 76 | MP0002210_abnormal_sex_determination | 0.71479091 |
| 77 | MP0003890_abnormal_embryonic-extraembry | 0.70127153 |
| 78 | MP0002735_abnormal_chemical_nociception | 0.69134835 |
| 79 | MP0001324_abnormal_eye_pigmentation | 0.69093580 |
| 80 | MP0000427_abnormal_hair_cycle | 0.67564024 |
| 81 | MP0003880_abnormal_central_pattern | 0.67288836 |
| 82 | MP0002572_abnormal_emotion/affect_behav | 0.66310316 |
| 83 | MP0004133_heterotaxia | 0.66217463 |
| 84 | MP0000653_abnormal_sex_gland | 0.66036049 |
| 85 | MP0005195_abnormal_posterior_eye | 0.65372372 |
| 86 | MP0004084_abnormal_cardiac_muscle | 0.65364136 |
| 87 | MP0002638_abnormal_pupillary_reflex | 0.65107235 |
| 88 | MP0003045_fibrosis | 0.64619789 |
| 89 | MP0004264_abnormal_extraembryonic_tissu | 0.64085148 |
| 90 | MP0002233_abnormal_nose_morphology | 0.64001062 |
| 91 | MP0001529_abnormal_vocalization | 0.60944646 |
| 92 | MP0005395_other_phenotype | 0.60527036 |
| 93 | MP0003950_abnormal_plasma_membrane | 0.59524344 |
| 94 | MP0003938_abnormal_ear_development | 0.59433071 |
| 95 | MP0004215_abnormal_myocardial_fiber | 0.58808615 |
| 96 | MP0002752_abnormal_somatic_nervous | 0.58123008 |
| 97 | MP0003137_abnormal_impulse_conducting | 0.57537230 |
| 98 | MP0003122_maternal_imprinting | 0.57516967 |
| 99 | MP0005394_taste/olfaction_phenotype | 0.57320161 |
| 100 | MP0005499_abnormal_olfactory_system | 0.57320161 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 4.86580427 |
| 2 | True hermaphroditism (HP:0010459) | 4.57321435 |
| 3 | Pancreatic cysts (HP:0001737) | 4.08382999 |
| 4 | Pancreatic fibrosis (HP:0100732) | 4.00258714 |
| 5 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.71567365 |
| 6 | Short chin (HP:0000331) | 3.70051781 |
| 7 | Abnormality of midbrain morphology (HP:0002418) | 3.43973242 |
| 8 | Molar tooth sign on MRI (HP:0002419) | 3.43973242 |
| 9 | Nephronophthisis (HP:0000090) | 3.40781029 |
| 10 | Concave nail (HP:0001598) | 3.33168905 |
| 11 | Attenuation of retinal blood vessels (HP:0007843) | 3.27425663 |
| 12 | Severe visual impairment (HP:0001141) | 3.18790276 |
| 13 | Cystic liver disease (HP:0006706) | 3.13642169 |
| 14 | Abolished electroretinogram (ERG) (HP:0000550) | 3.05290897 |
| 15 | Abnormal biliary tract physiology (HP:0012439) | 3.02981473 |
| 16 | Bile duct proliferation (HP:0001408) | 3.02981473 |
| 17 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.97283780 |
| 18 | Hypoplasia of the fovea (HP:0007750) | 2.97283780 |
| 19 | Progressive inability to walk (HP:0002505) | 2.91846820 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.90302735 |
| 21 | Hypothermia (HP:0002045) | 2.89459853 |
| 22 | Conical tooth (HP:0000698) | 2.84933537 |
| 23 | Thyroiditis (HP:0100646) | 2.73583846 |
| 24 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.68500865 |
| 25 | Male pseudohermaphroditism (HP:0000037) | 2.66793080 |
| 26 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.66322779 |
| 27 | Chronic hepatic failure (HP:0100626) | 2.55497253 |
| 28 | Gaze-evoked nystagmus (HP:0000640) | 2.52737432 |
| 29 | Postaxial foot polydactyly (HP:0001830) | 2.52078526 |
| 30 | Anencephaly (HP:0002323) | 2.51690753 |
| 31 | Abnormality of the fovea (HP:0000493) | 2.51545535 |
| 32 | Abnormality of the renal cortex (HP:0011035) | 2.46787183 |
| 33 | Menorrhagia (HP:0000132) | 2.43972280 |
| 34 | Medial flaring of the eyebrow (HP:0010747) | 2.42396460 |
| 35 | Severe combined immunodeficiency (HP:0004430) | 2.39051926 |
| 36 | Cerebellar dysplasia (HP:0007033) | 2.34573718 |
| 37 | Inability to walk (HP:0002540) | 2.28088403 |
| 38 | Facial diplegia (HP:0001349) | 2.28014677 |
| 39 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.27346103 |
| 40 | Congenital primary aphakia (HP:0007707) | 2.24851742 |
| 41 | Abnormality of macular pigmentation (HP:0008002) | 2.24505701 |
| 42 | Abnormality of eosinophils (HP:0001879) | 2.23899161 |
| 43 | Rimmed vacuoles (HP:0003805) | 2.23678612 |
| 44 | Sclerocornea (HP:0000647) | 2.21356529 |
| 45 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.20659021 |
| 46 | Hypoproteinemia (HP:0003075) | 2.15252634 |
| 47 | Renal cortical cysts (HP:0000803) | 2.14833402 |
| 48 | Abnormality of B cell number (HP:0010975) | 2.14297782 |
| 49 | Prominent supraorbital ridges (HP:0000336) | 2.13785200 |
| 50 | Brittle hair (HP:0002299) | 2.13719074 |
| 51 | Spinal muscular atrophy (HP:0007269) | 2.09963952 |
| 52 | Anhidrosis (HP:0000970) | 2.09540142 |
| 53 | Gait imbalance (HP:0002141) | 2.09205580 |
| 54 | Decreased central vision (HP:0007663) | 2.06896361 |
| 55 | Clumsiness (HP:0002312) | 2.03374475 |
| 56 | Pigmentary retinal degeneration (HP:0001146) | 2.02693994 |
| 57 | Absent eyebrow (HP:0002223) | 2.02091024 |
| 58 | Abnormality of the parathyroid morphology (HP:0011766) | 2.00347172 |
| 59 | Hemiparesis (HP:0001269) | 1.99712647 |
| 60 | Abnormality of alanine metabolism (HP:0010916) | 1.99668395 |
| 61 | Hyperalaninemia (HP:0003348) | 1.99668395 |
| 62 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.99668395 |
| 63 | Thyroid-stimulating hormone excess (HP:0002925) | 1.95972173 |
| 64 | Prolonged bleeding time (HP:0003010) | 1.95944667 |
| 65 | Intestinal atresia (HP:0011100) | 1.95079223 |
| 66 | Broad-based gait (HP:0002136) | 1.92772569 |
| 67 | Hypomagnesemia (HP:0002917) | 1.92409630 |
| 68 | Abnormal drinking behavior (HP:0030082) | 1.91714406 |
| 69 | Polydipsia (HP:0001959) | 1.91714406 |
| 70 | Type II lissencephaly (HP:0007260) | 1.91462691 |
| 71 | Rhinitis (HP:0012384) | 1.91309978 |
| 72 | Disproportionate short-trunk short stature (HP:0003521) | 1.88874391 |
| 73 | Congenital hepatic fibrosis (HP:0002612) | 1.87730369 |
| 74 | Spontaneous abortion (HP:0005268) | 1.87586721 |
| 75 | B lymphocytopenia (HP:0010976) | 1.87549855 |
| 76 | Chronic bronchitis (HP:0004469) | 1.86965408 |
| 77 | Abnormality of the ileum (HP:0001549) | 1.85506598 |
| 78 | Gonadotropin excess (HP:0000837) | 1.85104195 |
| 79 | Astigmatism (HP:0000483) | 1.84947119 |
| 80 | Central scotoma (HP:0000603) | 1.84784754 |
| 81 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.84250468 |
| 82 | Petechiae (HP:0000967) | 1.83262353 |
| 83 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.83044211 |
| 84 | Nephrogenic diabetes insipidus (HP:0009806) | 1.82578877 |
| 85 | Absent speech (HP:0001344) | 1.82347462 |
| 86 | Eosinophilia (HP:0001880) | 1.82241704 |
| 87 | Hypoplastic iliac wings (HP:0002866) | 1.82091073 |
| 88 | Meckel diverticulum (HP:0002245) | 1.81168672 |
| 89 | Premature skin wrinkling (HP:0100678) | 1.80451889 |
| 90 | Epistaxis (HP:0000421) | 1.77453915 |
| 91 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.75770391 |
| 92 | Enlarged kidneys (HP:0000105) | 1.75691684 |
| 93 | Sloping forehead (HP:0000340) | 1.75395619 |
| 94 | Abnormal ciliary motility (HP:0012262) | 1.75155220 |
| 95 | Tubular atrophy (HP:0000092) | 1.75041500 |
| 96 | Mesangial abnormality (HP:0001966) | 1.74074412 |
| 97 | Gonadal dysgenesis (HP:0000133) | 1.73908663 |
| 98 | Dandy-Walker malformation (HP:0001305) | 1.73767440 |
| 99 | Clubbing of toes (HP:0100760) | 1.73720364 |
| 100 | Occipital encephalocele (HP:0002085) | 1.72512752 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LATS1 | 5.27122763 |
| 2 | FRK | 5.22913165 |
| 3 | NUAK1 | 3.82117109 |
| 4 | MST4 | 3.02331438 |
| 5 | ACVR1B | 2.77262601 |
| 6 | PINK1 | 2.28561542 |
| 7 | MUSK | 2.27507776 |
| 8 | BMPR1B | 2.23008094 |
| 9 | TXK | 2.22916351 |
| 10 | IRAK1 | 2.17146998 |
| 11 | ZAK | 2.15910877 |
| 12 | ADRBK2 | 2.15195172 |
| 13 | TLK1 | 2.07671097 |
| 14 | GRK1 | 1.98473690 |
| 15 | IRAK2 | 1.93408487 |
| 16 | TRIM28 | 1.87184363 |
| 17 | KIT | 1.81823064 |
| 18 | MAP2K7 | 1.76603542 |
| 19 | CDC7 | 1.67419853 |
| 20 | MYLK | 1.64706466 |
| 21 | PIK3CG | 1.49032506 |
| 22 | BCKDK | 1.45658458 |
| 23 | PDK2 | 1.40494661 |
| 24 | VRK1 | 1.35747631 |
| 25 | STK39 | 1.35221513 |
| 26 | PLK2 | 1.34711192 |
| 27 | TAOK3 | 1.34164333 |
| 28 | NLK | 1.25422200 |
| 29 | TEC | 1.25040254 |
| 30 | PLK4 | 1.19870894 |
| 31 | STK3 | 1.19119175 |
| 32 | AKT3 | 1.17326218 |
| 33 | ERBB4 | 1.15602843 |
| 34 | MAP4K2 | 1.15300444 |
| 35 | CSNK1G3 | 1.09899944 |
| 36 | TNK2 | 1.05945248 |
| 37 | CSNK1G1 | 1.05750757 |
| 38 | WNK4 | 1.04987963 |
| 39 | WNK3 | 1.03354351 |
| 40 | CSNK1A1L | 1.01135089 |
| 41 | OXSR1 | 0.96087693 |
| 42 | INSRR | 0.92912365 |
| 43 | BCR | 0.88883140 |
| 44 | CDK8 | 0.87214161 |
| 45 | GRK6 | 0.86264593 |
| 46 | CSNK1G2 | 0.86097258 |
| 47 | BTK | 0.84518893 |
| 48 | EPHA3 | 0.82451449 |
| 49 | CDK12 | 0.82014836 |
| 50 | OBSCN | 0.81966115 |
| 51 | ERBB3 | 0.81913864 |
| 52 | MARK3 | 0.78433973 |
| 53 | PTK2B | 0.74593920 |
| 54 | CASK | 0.72438101 |
| 55 | PAK3 | 0.72118738 |
| 56 | TGFBR1 | 0.61760008 |
| 57 | DAPK2 | 0.60372764 |
| 58 | BRSK2 | 0.59976954 |
| 59 | ADRBK1 | 0.57923097 |
| 60 | MKNK2 | 0.56886138 |
| 61 | FER | 0.54583474 |
| 62 | TNIK | 0.51508364 |
| 63 | PIK3CA | 0.49309290 |
| 64 | MAP3K4 | 0.49270287 |
| 65 | PRKCE | 0.49066835 |
| 66 | MAPK15 | 0.46313478 |
| 67 | FLT3 | 0.45341555 |
| 68 | SYK | 0.44541660 |
| 69 | JAK1 | 0.44009456 |
| 70 | MAPK13 | 0.42955431 |
| 71 | STK38L | 0.42944759 |
| 72 | PBK | 0.42928188 |
| 73 | CSNK1A1 | 0.42131669 |
| 74 | RPS6KA5 | 0.41828848 |
| 75 | EGFR | 0.41716483 |
| 76 | STK38 | 0.40839049 |
| 77 | MKNK1 | 0.39360205 |
| 78 | ITK | 0.39339500 |
| 79 | MINK1 | 0.38860749 |
| 80 | CSNK1D | 0.37787066 |
| 81 | RPS6KA4 | 0.37637044 |
| 82 | PRKCQ | 0.36631236 |
| 83 | NEK2 | 0.35791645 |
| 84 | MELK | 0.35351098 |
| 85 | STK16 | 0.32861097 |
| 86 | CDK3 | 0.32193792 |
| 87 | PRKAA1 | 0.31492408 |
| 88 | ROCK1 | 0.31330520 |
| 89 | KDR | 0.30732878 |
| 90 | CAMK2A | 0.29984956 |
| 91 | ERBB2 | 0.29916546 |
| 92 | PRKCG | 0.28001418 |
| 93 | DAPK1 | 0.27420846 |
| 94 | PRKAA2 | 0.24907504 |
| 95 | CHUK | 0.24485801 |
| 96 | SIK3 | 0.24327738 |
| 97 | IKBKB | 0.24125131 |
| 98 | WEE1 | 0.23343502 |
| 99 | ABL1 | 0.23171795 |
| 100 | ATM | 0.22638201 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.65401100 |
| 2 | Phototransduction_Homo sapiens_hsa04744 | 2.61637638 |
| 3 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.53271207 |
| 4 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.50875934 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.30451105 |
| 6 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.26984315 |
| 7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.21845335 |
| 8 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.17683941 |
| 9 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.08633966 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.07201534 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.04331957 |
| 12 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.01371385 |
| 13 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.00406457 |
| 14 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.98400992 |
| 15 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.91468404 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.88214635 |
| 17 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.84109740 |
| 18 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.81180719 |
| 19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.79211473 |
| 20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.76801632 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.72760819 |
| 22 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.71303239 |
| 23 | Nicotine addiction_Homo sapiens_hsa05033 | 1.69931982 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.63209382 |
| 25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.60249850 |
| 26 | Salivary secretion_Homo sapiens_hsa04970 | 1.48861962 |
| 27 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.45300538 |
| 28 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.43987174 |
| 29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.43266913 |
| 30 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.39894631 |
| 31 | ABC transporters_Homo sapiens_hsa02010 | 1.39070797 |
| 32 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.34877067 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.32743404 |
| 34 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.29052182 |
| 35 | Homologous recombination_Homo sapiens_hsa03440 | 1.26519973 |
| 36 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.26508848 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 1.26010268 |
| 38 | Platelet activation_Homo sapiens_hsa04611 | 1.25293657 |
| 39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21211944 |
| 40 | Retinol metabolism_Homo sapiens_hsa00830 | 1.17429659 |
| 41 | Circadian rhythm_Homo sapiens_hsa04710 | 1.17000115 |
| 42 | Taste transduction_Homo sapiens_hsa04742 | 1.16876590 |
| 43 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.16767976 |
| 44 | Lysine degradation_Homo sapiens_hsa00310 | 1.16250583 |
| 45 | Mismatch repair_Homo sapiens_hsa03430 | 1.15463765 |
| 46 | Circadian entrainment_Homo sapiens_hsa04713 | 1.14711724 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.11928413 |
| 48 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.03026401 |
| 49 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97643895 |
| 50 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.94162503 |
| 51 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.94147236 |
| 52 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.93768562 |
| 53 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.92235978 |
| 54 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.89104852 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.87147356 |
| 56 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.86747123 |
| 57 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.84765840 |
| 58 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.84379476 |
| 59 | Purine metabolism_Homo sapiens_hsa00230 | 0.83231618 |
| 60 | Renin secretion_Homo sapiens_hsa04924 | 0.81595186 |
| 61 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.80765273 |
| 62 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.76823111 |
| 63 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.74897803 |
| 64 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.74872096 |
| 65 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.74122238 |
| 66 | DNA replication_Homo sapiens_hsa03030 | 0.72903541 |
| 67 | Alcoholism_Homo sapiens_hsa05034 | 0.72404191 |
| 68 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.72330309 |
| 69 | RNA degradation_Homo sapiens_hsa03018 | 0.70369076 |
| 70 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.70019164 |
| 71 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.69591627 |
| 72 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.68563373 |
| 73 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.67523531 |
| 74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65494233 |
| 75 | Long-term depression_Homo sapiens_hsa04730 | 0.64615813 |
| 76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.62450990 |
| 77 | Morphine addiction_Homo sapiens_hsa05032 | 0.61937270 |
| 78 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61640816 |
| 79 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.61541488 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60449812 |
| 81 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59202962 |
| 82 | GABAergic synapse_Homo sapiens_hsa04727 | 0.58875231 |
| 83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.57867815 |
| 84 | Mineral absorption_Homo sapiens_hsa04978 | 0.55934326 |
| 85 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.54122513 |
| 86 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.53256191 |
| 87 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.51771060 |
| 88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.51602363 |
| 89 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.50598450 |
| 90 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.47560019 |
| 91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.47541802 |
| 92 | Insulin secretion_Homo sapiens_hsa04911 | 0.45971043 |
| 93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.40196083 |
| 94 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.36739700 |
| 95 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.35703673 |
| 96 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.33112998 |
| 97 | Gap junction_Homo sapiens_hsa04540 | 0.32629111 |
| 98 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.31776094 |
| 99 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.31656838 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.30651798 |

