AMBP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.53946323
2L-phenylalanine catabolic process (GO:0006559)7.53946323
3L-phenylalanine metabolic process (GO:0006558)7.22658378
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.22658378
5aromatic amino acid family catabolic process (GO:0009074)6.75029059
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.47662117
7tryptophan catabolic process (GO:0006569)6.07978130
8indole-containing compound catabolic process (GO:0042436)6.07978130
9indolalkylamine catabolic process (GO:0046218)6.07978130
10kynurenine metabolic process (GO:0070189)5.97878010
11bile acid biosynthetic process (GO:0006699)5.89154509
12negative regulation of fibrinolysis (GO:0051918)5.86563694
13regulation of plasminogen activation (GO:0010755)5.82001776
14exogenous drug catabolic process (GO:0042738)5.78615461
15glyoxylate metabolic process (GO:0046487)5.78592280
16epoxygenase P450 pathway (GO:0019373)5.78558834
17high-density lipoprotein particle remodeling (GO:0034375)5.75889938
18tryptophan metabolic process (GO:0006568)5.72804564
19urea cycle (GO:0000050)5.69370302
20urea metabolic process (GO:0019627)5.69370302
21regulation of fibrinolysis (GO:0051917)5.63659419
22alpha-linolenic acid metabolic process (GO:0036109)5.50233621
23regulation of protein activation cascade (GO:2000257)5.49329680
24protein carboxylation (GO:0018214)5.46720895
25peptidyl-glutamic acid carboxylation (GO:0017187)5.46720895
26complement activation, alternative pathway (GO:0006957)5.43725557
27sulfur amino acid catabolic process (GO:0000098)5.32335941
28cysteine metabolic process (GO:0006534)5.31176322
29nitrogen cycle metabolic process (GO:0071941)5.22907320
30intestinal cholesterol absorption (GO:0030299)5.15969381
31regulation of complement activation (GO:0030449)5.10678286
32reverse cholesterol transport (GO:0043691)5.08318257
33serine family amino acid catabolic process (GO:0009071)5.06827119
34regulation of cholesterol esterification (GO:0010872)5.06687146
35omega-hydroxylase P450 pathway (GO:0097267)5.05683753
36bile acid metabolic process (GO:0008206)5.04043791
37plasma lipoprotein particle remodeling (GO:0034369)4.94916738
38protein-lipid complex remodeling (GO:0034368)4.94916738
39macromolecular complex remodeling (GO:0034367)4.94916738
40regulation of triglyceride catabolic process (GO:0010896)4.94318560
41aromatic amino acid family metabolic process (GO:0009072)4.90994353
42negative regulation of blood coagulation (GO:0030195)4.89595774
43negative regulation of hemostasis (GO:1900047)4.89595774
44fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.83653589
45phospholipid efflux (GO:0033700)4.77207006
46tyrosine metabolic process (GO:0006570)4.76123108
47homocysteine metabolic process (GO:0050667)4.72777838
48acylglycerol homeostasis (GO:0055090)4.69295720
49triglyceride homeostasis (GO:0070328)4.69295720
50negative regulation of sterol transport (GO:0032372)4.61851087
51negative regulation of cholesterol transport (GO:0032375)4.61851087
52regulation of apoptotic cell clearance (GO:2000425)4.60167454
53alpha-amino acid catabolic process (GO:1901606)4.59481682
54regulation of humoral immune response (GO:0002920)4.59179261
55plasma lipoprotein particle clearance (GO:0034381)4.56171482
56positive regulation of blood coagulation (GO:0030194)4.55393647
57positive regulation of hemostasis (GO:1900048)4.55393647
58amino-acid betaine metabolic process (GO:0006577)4.54092549
59lysine metabolic process (GO:0006553)4.53819092
60lysine catabolic process (GO:0006554)4.53819092
61negative regulation of coagulation (GO:0050819)4.48220535
62protein-lipid complex subunit organization (GO:0071825)4.46842374
63glycine metabolic process (GO:0006544)4.38857562
64negative regulation of wound healing (GO:0061045)4.38565557
65cellular ketone body metabolic process (GO:0046950)4.38447638
66cholesterol efflux (GO:0033344)4.37864113
67bile acid and bile salt transport (GO:0015721)4.35678536
68indolalkylamine metabolic process (GO:0006586)4.30978491
69imidazole-containing compound metabolic process (GO:0052803)4.30785052
70drug metabolic process (GO:0017144)4.30783845
71coenzyme catabolic process (GO:0009109)4.29558968
72cellular amino acid catabolic process (GO:0009063)4.22405504
73glutamate metabolic process (GO:0006536)4.22153937
74amine catabolic process (GO:0009310)4.21114986
75cellular biogenic amine catabolic process (GO:0042402)4.21114986
76plasma lipoprotein particle assembly (GO:0034377)4.19517449
77ethanol metabolic process (GO:0006067)4.18148745
78phenylpropanoid metabolic process (GO:0009698)4.18093013
79positive regulation of coagulation (GO:0050820)4.16830283
80serine family amino acid metabolic process (GO:0009069)4.15506237
81fibrinolysis (GO:0042730)4.15004074
82cellular glucuronidation (GO:0052695)4.14938094
83negative regulation of complement activation (GO:0045916)4.14515236
84benzene-containing compound metabolic process (GO:0042537)4.09249968
85low-density lipoprotein particle remodeling (GO:0034374)4.07651190
86cellular modified amino acid catabolic process (GO:0042219)4.04759675
87dicarboxylic acid biosynthetic process (GO:0043650)4.02419629
88arginine metabolic process (GO:0006525)4.02209604
89serine family amino acid biosynthetic process (GO:0009070)4.00184627
90blood coagulation, intrinsic pathway (GO:0007597)3.99802157
91ethanol oxidation (GO:0006069)3.99473432
92aldehyde catabolic process (GO:0046185)3.99336184
93oxidative demethylation (GO:0070989)3.97740791
94positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.93546277
95positive regulation of lipoprotein lipase activity (GO:0051006)3.91350451
96positive regulation of triglyceride lipase activity (GO:0061365)3.91350451
97positive regulation of fatty acid biosynthetic process (GO:0045723)3.87133634
98very-low-density lipoprotein particle assembly (GO:0034379)3.84693617
99drug catabolic process (GO:0042737)3.82952727
100negative regulation of lipase activity (GO:0060192)3.82717899
101phospholipid homeostasis (GO:0055091)3.82230448
102complement activation, classical pathway (GO:0006958)3.81698086
103positive regulation of lipid catabolic process (GO:0050996)3.80482320
104protein activation cascade (GO:0072376)3.80052563
105cholesterol homeostasis (GO:0042632)3.79989721
106proline metabolic process (GO:0006560)3.79437464
107ketone body metabolic process (GO:1902224)3.79345915
108complement activation (GO:0006956)3.77439082
109plasma lipoprotein particle organization (GO:0071827)3.77169234
110protein-lipid complex assembly (GO:0065005)3.75996604
111sterol homeostasis (GO:0055092)3.73680512
112cytolysis (GO:0019835)3.68790562
113carboxylic acid catabolic process (GO:0046395)3.68583309
114organic acid catabolic process (GO:0016054)3.68583309
115uronic acid metabolic process (GO:0006063)3.67995419
116glucuronate metabolic process (GO:0019585)3.67995419
117regulation of bile acid biosynthetic process (GO:0070857)3.67384175
118acute-phase response (GO:0006953)3.66823339
119heme transport (GO:0015886)3.62264040
120regulation of cholesterol homeostasis (GO:2000188)3.62106591
121lipoprotein metabolic process (GO:0042157)3.60713035
122negative regulation of protein activation cascade (GO:2000258)3.58886266
123acetyl-CoA metabolic process (GO:0006084)3.58879957
124short-chain fatty acid metabolic process (GO:0046459)3.58457715
125acute inflammatory response (GO:0002526)3.54206945
126regulation of lipoprotein particle clearance (GO:0010984)3.49407080
127cholesterol transport (GO:0030301)3.45325143
128sterol transport (GO:0015918)3.45325143
129doxorubicin metabolic process (GO:0044598)3.40110868
130daunorubicin metabolic process (GO:0044597)3.40110868
131polyketide metabolic process (GO:0030638)3.40110868
132positive regulation of extracellular matrix organization (GO:1903055)3.35001151

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.36831485
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.19316617
3EGR1_23403033_ChIP-Seq_LIVER_Mouse7.04970992
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.49076284
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.29417210
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.21251493
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.86698619
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.08048287
9* NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.01959384
10TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.07913738
11HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.03252212
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse12.0815406
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.97764201
14* FOXA2_19822575_ChIP-Seq_HepG2_Human1.62026212
15CLOCK_20551151_ChIP-Seq_293T_Human1.60974909
16HTT_18923047_ChIP-ChIP_STHdh_Human1.54943133
17GATA1_22025678_ChIP-Seq_K562_Human1.53608361
18CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.49326574
19* HNF4A_19822575_ChIP-Seq_HepG2_Human1.41454030
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.31161843
21TRIM28_21343339_ChIP-Seq_HEK293_Human1.26536710
22PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.26282400
23RXRA_24833708_ChIP-Seq_LIVER_Mouse1.20430185
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.18239270
25STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17874247
26ESR1_15608294_ChIP-ChIP_MCF-7_Human1.14808546
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.11214384
28TCF4_18268006_ChIP-ChIP_LS174T_Human1.10845021
29ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01484951
30TP63_17297297_ChIP-ChIP_HaCaT_Human0.98829343
31IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.96736865
32SOX2_27498859_Chip-Seq_STOMACH_Mouse0.95455620
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.94176946
34PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.89841233
35IRF8_22096565_ChIP-ChIP_GC-B_Human0.87418876
36RARG_19884340_ChIP-ChIP_MEFs_Mouse0.86095481
37PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.84086020
38ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.83271021
39GATA4_25053715_ChIP-Seq_YYC3_Human0.82262132
40AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82004673
41AR_21909140_ChIP-Seq_LNCAP_Human0.81594345
42SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.80238192
43ZNF263_19887448_ChIP-Seq_K562_Human0.78331565
44ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.76932472
45POU5F1_16518401_ChIP-PET_MESCs_Mouse0.76554356
46RARA_24833708_ChIP-Seq_LIVER_Mouse0.75937793
47SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.75571691
48KAP1_22055183_ChIP-Seq_ESCs_Mouse0.74574246
49BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74458141
50CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.70965095
51Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.70763828
52HIF1A_21447827_ChIP-Seq_MCF-7_Human0.69806418
53FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.69341247
54AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.67832728
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.66785478
56SOX2_21211035_ChIP-Seq_LN229_Human0.66462187
57ESR2_21235772_ChIP-Seq_MCF-7_Human0.66181389
58RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.65142961
59GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.65082533
60RAC3_21632823_ChIP-Seq_H3396_Human0.64868917
61RARB_24833708_ChIP-Seq_LIVER_Mouse0.64435734
62* SALL4_18804426_ChIP-ChIP_XEN_Mouse0.64246442
63NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.63488254
64NRF2_20460467_ChIP-Seq_MEFs_Mouse0.63488254
65DNAJC2_21179169_ChIP-ChIP_NT2_Human0.63293557
66NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.62432696
67BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.60235692
68NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.60112739
69NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.60108557
70RAD21_21589869_ChIP-Seq_MESCs_Mouse0.59924915
71NFIB_24661679_ChIP-Seq_LUNG_Mouse0.59754140
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.58304422
73SMC4_20622854_ChIP-Seq_HELA_Human0.57759452
74CEBPB_22108803_ChIP-Seq_LS180_Human0.57264085
75NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.56928006
76CSB_26484114_Chip-Seq_FIBROBLAST_Human0.56651850
77PCGF2_27294783_Chip-Seq_NPCs_Mouse0.55830936
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.55503845
79NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.55409332
80JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.54462605
81LXR_22292898_ChIP-Seq_THP-1_Human0.54064126
82EGR1_19032775_ChIP-ChIP_M12_Human0.53717694
83SMAD1_18555785_Chip-Seq_ESCs_Mouse0.53411031
84STAT3_1855785_ChIP-Seq_MESCs_Mouse0.53406949
85NFE2_27457419_Chip-Seq_LIVER_Mouse0.53236629
86AR_20517297_ChIP-Seq_VCAP_Human0.52670233
87SOX11_22085726_ChIP-Seq_ESNs_Mouse0.52533152
88* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.52447359
89* GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.52363646
90* FOXA1_25552417_ChIP-Seq_VCAP_Human0.51873735
91* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.50281961
92* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.49656229
93* MYC_19915707_ChIP-ChIP_AK7_Human0.48770831
94ESRRB_18555785_Chip-Seq_ESCs_Mouse0.48686790
95* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.48502104
96EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.48456262
97GATA1_19941826_ChIP-Seq_K562_Human0.47684585
98CBP_21632823_ChIP-Seq_H3396_Human0.47480664
99RUNX1_27457419_Chip-Seq_LIVER_Mouse0.47247974
100PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.47224185
101ESET_19884257_ChIP-Seq_ESCs_Mouse0.46528730
102P53_21459846_ChIP-Seq_SAOS-2_Human0.46347057
103ELF1_20517297_ChIP-Seq_JURKAT_Human0.46317164
104ESR1_21235772_ChIP-Seq_MCF-7_Human0.46278100
105SRY_22984422_ChIP-ChIP_TESTIS_Rat0.46110670
106PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.44727182
107STAT1_17558387_ChIP-Seq_HELA_Human0.44436281
108GATA1_19941827_ChIP-Seq_MEL_Mouse0.43856673
109FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.43362139
110CDX2_20551321_ChIP-Seq_CACO-2_Human0.43328054
111SPI1_20517297_ChIP-Seq_HL60_Human0.43032916
112GATA3_24758297_ChIP-Seq_MCF-7_Human0.42946032
113E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.42816360
114FOXO3_23340844_ChIP-Seq_DLD1_Human0.42457358
115GATA6_25053715_ChIP-Seq_YYC3_Human0.42375464
116PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.42197197
117E2F1_20622854_ChIP-Seq_HELA_Human0.42008328
118GATA2_19941826_ChIP-Seq_K562_Human0.42007324
119TAF2_19829295_ChIP-Seq_ESCs_Human0.41925520
120PPAR_26484153_Chip-Seq_NCI-H1993_Human0.39960398
121* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.39251824
122ESR1_20079471_ChIP-ChIP_T-47D_Human0.38376609
123STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.38087365
124TAF15_26573619_Chip-Seq_HEK293_Human0.37557204
125CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.36118525
126BCAT_22108803_ChIP-Seq_LS180_Human0.36091958
127ERG_21242973_ChIP-ChIP_JURKAT_Human0.36052608
128ERG_20517297_ChIP-Seq_VCAP_Human0.34819033
129* MYC_27129775_Chip-Seq_CORNEA_Mouse0.34527903
130LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.33901407
131CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.33704802
132NCOR_22424771_ChIP-Seq_293T_Human0.33640364
133FOXH1_21741376_ChIP-Seq_EPCs_Human0.33386018
134* SPI1_26923725_Chip-Seq_HPCs_Mouse0.33226484
135SOX2_20726797_ChIP-Seq_SW620_Human0.32730141
136CDX2_22108803_ChIP-Seq_LS180_Human0.32695702

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.28330408
2MP0005360_urolithiasis7.47102535
3MP0005085_abnormal_gallbladder_physiolo6.42443956
4MP0005365_abnormal_bile_salt6.20670435
5MP0008875_abnormal_xenobiotic_pharmacok5.00988951
6MP0003806_abnormal_nucleotide_metabolis4.23649390
7MP0003252_abnormal_bile_duct3.92031739
8MP0010329_abnormal_lipoprotein_level3.63197752
9MP0009840_abnormal_foam_cell3.37026317
10MP0005083_abnormal_biliary_tract3.16298256
11MP0003195_calcinosis2.82791029
12MP0005332_abnormal_amino_acid2.73205380
13MP0001666_abnormal_nutrient_absorption2.63290745
14MP0003191_abnormal_cellular_cholesterol2.45803976
15MP0000609_abnormal_liver_physiology2.18266692
16MP0004019_abnormal_vitamin_homeostasis2.12576934
17MP0002118_abnormal_lipid_homeostasis2.10188590
18MP0002138_abnormal_hepatobiliary_system2.08247386
19MP0003122_maternal_imprinting2.00208961
20MP0003868_abnormal_feces_composition1.95629322
21MP0005319_abnormal_enzyme/_coenzyme1.81975190
22MP0001764_abnormal_homeostasis1.67802695
23MP0009697_abnormal_copulation1.63656264
24MP0005584_abnormal_enzyme/coenzyme_acti1.55451373
25MP0003011_delayed_dark_adaptation1.50009592
26MP0001915_intracranial_hemorrhage1.46499640
27MP0000566_synostosis1.44633629
28MP0003656_abnormal_erythrocyte_physiolo1.33899617
29MP0005451_abnormal_body_composition1.33762313
30MP0002089_abnormal_postnatal_growth/wei1.28411492
31MP0003186_abnormal_redox_activity1.25976300
32MP0009643_abnormal_urine_homeostasis1.23745053
33MP0005058_abnormal_lysosome_morphology1.23591114
34MP0000598_abnormal_liver_morphology1.19831683
35MP0003705_abnormal_hypodermis_morpholog1.15062476
36MP0000604_amyloidosis1.12758082
37MP0005647_abnormal_sex_gland1.10971891
38MP0002254_reproductive_system_inflammat1.04466594
39MP0009764_decreased_sensitivity_to1.04330524
40MP0009763_increased_sensitivity_to1.03126147
41MP0010368_abnormal_lymphatic_system1.00780586
42MP0003123_paternal_imprinting0.98818065
43MP0005636_abnormal_mineral_homeostasis0.95947236
44MP0003172_abnormal_lysosome_physiology0.91323585
45MP0008469_abnormal_protein_level0.90592207
46MP0005084_abnormal_gallbladder_morpholo0.90243098
47MP0009642_abnormal_blood_homeostasis0.88280097
48MP0005408_hypopigmentation0.87046090
49MP0005220_abnormal_exocrine_pancreas0.82803142
50MP0006036_abnormal_mitochondrial_physio0.81506891
51MP0005376_homeostasis/metabolism_phenot0.80088427
52MP0002078_abnormal_glucose_homeostasis0.79645284
53MP0009765_abnormal_xenobiotic_induced0.77847958
54MP0005670_abnormal_white_adipose0.75035581
55MP0002876_abnormal_thyroid_physiology0.73912060
56MP0003879_abnormal_hair_cell0.71092007
57MP0002971_abnormal_brown_adipose0.70701490
58MP0005334_abnormal_fat_pad0.68487358
59MP0009053_abnormal_anal_canal0.68332812
60MP0003690_abnormal_glial_cell0.67148596
61MP0001661_extended_life_span0.66411794
62MP0004130_abnormal_muscle_cell0.65714360
63MP0004272_abnormal_basement_membrane0.64827357
64MP0005535_abnormal_body_temperature0.64658431
65MP0003329_amyloid_beta_deposits0.64466728
66MP0005167_abnormal_blood-brain_barrier0.63107475
67MP0005266_abnormal_metabolism0.63083057
68MP0000639_abnormal_adrenal_gland0.62814408
69MP0005187_abnormal_penis_morphology0.59654571
70MP0001756_abnormal_urination0.58744432
71MP0002282_abnormal_trachea_morphology0.57878758
72MP0005464_abnormal_platelet_physiology0.57824570
73MP0005448_abnormal_energy_balance0.55335922
74MP0006035_abnormal_mitochondrial_morpho0.54017542
75MP0002928_abnormal_bile_duct0.53769539
76MP0005409_darkened_coat_color0.52929946
77MP0005395_other_phenotype0.48983791
78MP0003638_abnormal_response/metabolism_0.45666978
79MP0002822_catalepsy0.45142849
80MP0008873_increased_physiological_sensi0.44994036
81MP0003718_maternal_effect0.44945917
82MP0002136_abnormal_kidney_physiology0.44735539
83MP0009780_abnormal_chondrocyte_physiolo0.43559849
84MP0005023_abnormal_wound_healing0.43555060
85MP0005257_abnormal_intraocular_pressure0.42950102
86MP0003436_decreased_susceptibility_to0.42546469
87MP0008874_decreased_physiological_sensi0.41998720
88MP0002249_abnormal_larynx_morphology0.41949843
89MP0003724_increased_susceptibility_to0.41444998
90MP0003953_abnormal_hormone_level0.41376281
91MP0003075_altered_response_to0.40814590
92MP0004782_abnormal_surfactant_physiolog0.39277939
93MP0002837_dystrophic_cardiac_calcinosis0.39071937
94MP0009672_abnormal_birth_weight0.38431658
95MP0005166_decreased_susceptibility_to0.38199911
96MP0005248_abnormal_Harderian_gland0.37230132
97MP0003632_abnormal_nervous_system0.36694899
98MP0003567_abnormal_fetal_cardiomyocyte0.36070750
99MP0005666_abnormal_adipose_tissue0.35869264
100MP0008872_abnormal_physiological_respon0.35387216
101MP0000920_abnormal_myelination0.34478378
102MP0000579_abnormal_nail_morphology0.34103385
103MP0005377_hearing/vestibular/ear_phenot0.33990364
104MP0003878_abnormal_ear_physiology0.33990364
105MP0009384_cardiac_valve_regurgitation0.33981398
106MP0002090_abnormal_vision0.33732479
107MP0004381_abnormal_hair_follicle0.33601913
108MP0004883_abnormal_blood_vessel0.33438351
109MP0002796_impaired_skin_barrier0.32688881
110MP0003950_abnormal_plasma_membrane0.32589701
111MP0006054_spinal_hemorrhage0.32524729
112MP0009115_abnormal_fat_cell0.32493810
113MP0003183_abnormal_peptide_metabolism0.32313457
114MP0001243_abnormal_dermal_layer0.32253986
115MP0000249_abnormal_blood_vessel0.32224405
116MP0000003_abnormal_adipose_tissue0.31963025
117MP0001324_abnormal_eye_pigmentation0.30832128
118MP0003121_genomic_imprinting0.30792416
119MP0002168_other_aberrant_phenotype0.30369575
120MP0002970_abnormal_white_adipose0.30363865
121MP0001845_abnormal_inflammatory_respons0.29326273
122MP0000230_abnormal_systemic_arterial0.28942056
123MP0001881_abnormal_mammary_gland0.28937391
124MP0006082_CNS_inflammation0.28663931
125MP0001853_heart_inflammation0.27709947
126MP0003566_abnormal_cell_adhesion0.27603015
127MP0002909_abnormal_adrenal_gland0.27175520
128MP0002933_joint_inflammation0.27147064
129MP0005164_abnormal_response_to0.27040662
130MP0003943_abnormal_hepatobiliary_system0.26423242
131MP0003941_abnormal_skin_development0.26332907
132MP0000858_altered_metastatic_potential0.25872388
133MP0003115_abnormal_respiratory_system0.25861401
134MP0002132_abnormal_respiratory_system0.25449117
135MP0004264_abnormal_extraembryonic_tissu0.24773877
136MP0001944_abnormal_pancreas_morphology0.24746314

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.53412362
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.37461013
3Intrahepatic cholestasis (HP:0001406)7.26490456
4Prolonged partial thromboplastin time (HP:0003645)6.69487133
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.64349620
6Hypobetalipoproteinemia (HP:0003563)6.44692422
7Xanthomatosis (HP:0000991)6.31106886
8Hyperlipoproteinemia (HP:0010980)5.52113880
9Complement deficiency (HP:0004431)5.49805557
10Joint hemorrhage (HP:0005261)4.92789631
11Hypolipoproteinemia (HP:0010981)4.86798153
12Abnormality of the common coagulation pathway (HP:0010990)4.64561439
13Hyperammonemia (HP:0001987)4.55797366
14Epidermoid cyst (HP:0200040)4.46403520
15Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.43974899
16Hyperglycinemia (HP:0002154)4.33260670
17Hypoalphalipoproteinemia (HP:0003233)4.26830417
18Abnormality of methionine metabolism (HP:0010901)4.24150716
19Ketosis (HP:0001946)4.21551545
20Abnormality of sulfur amino acid metabolism (HP:0004339)4.18652951
21Fat malabsorption (HP:0002630)4.13795047
22Abnormality of glutamine family amino acid metabolism (HP:0010902)4.08798426
23Abnormality of aspartate family amino acid metabolism (HP:0010899)4.06087938
24Abnormality of complement system (HP:0005339)4.01926369
25Hypoglycemic coma (HP:0001325)3.95755490
26Abnormality of the intrinsic pathway (HP:0010989)3.87468099
27Abnormality of glycine metabolism (HP:0010895)3.82444304
28Abnormality of serine family amino acid metabolism (HP:0010894)3.82444304
29Hyperglycinuria (HP:0003108)3.81854687
30Abnormality of pyrimidine metabolism (HP:0004353)3.80013702
31Conjugated hyperbilirubinemia (HP:0002908)3.69166964
32Hypercholesterolemia (HP:0003124)3.63356752
33Hyperbilirubinemia (HP:0002904)3.38300045
34Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.32026939
35Abnormality of fatty-acid metabolism (HP:0004359)3.27203095
36Spontaneous abortion (HP:0005268)3.24295423
37Steatorrhea (HP:0002570)3.10433174
38Purpura (HP:0000979)3.09798105
39Hypochromic microcytic anemia (HP:0004840)3.05457552
40Hepatocellular carcinoma (HP:0001402)3.02521819
41Abnormality of nucleobase metabolism (HP:0010932)3.02194758
42Abnormality of serum amino acid levels (HP:0003112)3.01587417
43Ketoacidosis (HP:0001993)3.00421416
44Delayed CNS myelination (HP:0002188)2.98578401
45Myocardial infarction (HP:0001658)2.91324947
46Systemic lupus erythematosus (HP:0002725)2.77733497
47Skin nodule (HP:0200036)2.77314472
48Osteomalacia (HP:0002749)2.72603382
49Acanthocytosis (HP:0001927)2.72081353
50Metabolic acidosis (HP:0001942)2.71596072
51Abnormality of purine metabolism (HP:0004352)2.63285286
52Hypoglycemic seizures (HP:0002173)2.61142389
53Lethargy (HP:0001254)2.56567076
54Abnormal gallbladder morphology (HP:0012437)2.54377476
55Glomerulonephritis (HP:0000099)2.53542505
56Vascular calcification (HP:0004934)2.51771504
57Abnormal gallbladder physiology (HP:0012438)2.51520433
58Cholecystitis (HP:0001082)2.51520433
59Dicarboxylic aciduria (HP:0003215)2.51468844
60Abnormality of dicarboxylic acid metabolism (HP:0010995)2.51468844
61Arthropathy (HP:0003040)2.51019822
62Cholelithiasis (HP:0001081)2.47121538
63Gout (HP:0001997)2.44496973
64Recurrent gram-negative bacterial infections (HP:0005420)2.43694641
65Amyloidosis (HP:0011034)2.43659717
66Spastic diplegia (HP:0001264)2.41986590
67Mitral stenosis (HP:0001718)2.40864627
68Cerebral edema (HP:0002181)2.40537002
69Gingival bleeding (HP:0000225)2.36412293
70Pulmonary embolism (HP:0002204)2.33893093
71Irritability (HP:0000737)2.33673050
72Neonatal onset (HP:0003623)2.32097379
73Reduced antithrombin III activity (HP:0001976)2.30417908
74Abnormality of the Achilles tendon (HP:0005109)2.29683107
75Esophageal varix (HP:0002040)2.28450371
76Abnormality of carpal bone ossification (HP:0006257)2.26515129
77Abnormal tarsal ossification (HP:0008369)2.26322535
78Cardiovascular calcification (HP:0011915)2.23025529
79Late onset (HP:0003584)2.22347041
80Malnutrition (HP:0004395)2.19643381
81Menorrhagia (HP:0000132)2.18807405
82Thrombophlebitis (HP:0004418)2.17792957
83Enlarged kidneys (HP:0000105)2.16348100
84Poikilocytosis (HP:0004447)2.14642772
85Pancreatitis (HP:0001733)2.13821117
86Hyperinsulinemic hypoglycemia (HP:0000825)2.13534752
87Sensorimotor neuropathy (HP:0007141)2.10535563
88Brushfield spots (HP:0001088)2.10296512
89Increased serum pyruvate (HP:0003542)2.09265299
90Abnormality of the gallbladder (HP:0005264)2.05664782
91Vomiting (HP:0002013)2.03352699
92Generalized aminoaciduria (HP:0002909)2.00794678
93Hemorrhage of the eye (HP:0011885)2.00311865
94Opisthotonus (HP:0002179)1.98620273
95Abnormality of iron homeostasis (HP:0011031)1.98586532
96Potter facies (HP:0002009)1.97917040
97Facial shape deformation (HP:0011334)1.97917040
98Abnormality of transition element cation homeostasis (HP:0011030)1.95197484
99Rickets (HP:0002748)1.91677212
100Abnormality of glycolysis (HP:0004366)1.88317320
101Abnormal cartilage morphology (HP:0002763)1.86088541
102Bifid scrotum (HP:0000048)1.85945975
103Hyperglycemia (HP:0003074)1.84506369
104Renal cortical cysts (HP:0000803)1.81616917
105Hypophosphatemic rickets (HP:0004912)1.81595595
106Abnormal enzyme/coenzyme activity (HP:0012379)1.80935890
107Abnormality of proline metabolism (HP:0010907)1.79706995
108Hydroxyprolinuria (HP:0003080)1.79706995
109Elevated hepatic transaminases (HP:0002910)1.79332698
110Pancreatic islet-cell hyperplasia (HP:0004510)1.78954631
111Nephritis (HP:0000123)1.78497951
112Alkalosis (HP:0001948)1.76344773
113Gangrene (HP:0100758)1.74391278
114Broad alveolar ridges (HP:0000187)1.73602817
115Status epilepticus (HP:0002133)1.73111838
116Abnormality of the lumbar spine (HP:0100712)1.72546407
117Reticulocytosis (HP:0001923)1.72342701
118Hyperphosphaturia (HP:0003109)1.71695191
119Epistaxis (HP:0000421)1.71539729
120Flat acetabular roof (HP:0003180)1.68512025
121Glycosuria (HP:0003076)1.67103345
122Abnormality of urine glucose concentration (HP:0011016)1.67103345
123Fair hair (HP:0002286)1.66598023
124Increased serum ferritin (HP:0003281)1.64940642
125Elevated alkaline phosphatase (HP:0003155)1.63151163
126Abnormal hand bone ossification (HP:0010660)1.62633250
127Vaginal fistula (HP:0004320)1.62517184
128Abnormal ossification of hand bones (HP:0005921)1.61149162
129Joint swelling (HP:0001386)1.59218217
130Abnormal delivery (HP:0001787)1.58745810
131Abnormality of alkaline phosphatase activity (HP:0004379)1.55764318
132Small epiphyses (HP:0010585)1.53573552
133Back pain (HP:0003418)1.52816248
134Widely patent fontanelles and sutures (HP:0004492)1.52006795
135Abnormality of the nasal septum (HP:0000419)1.51243578

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.07554606
2FGFR44.66626259
3SIK14.46736057
4ERN14.46008175
5TAOK33.18952942
6INSRR3.07939770
7ERBB43.01685079
8WNK42.77998155
9CDK122.50968848
10MAP2K42.24397351
11PKN22.20153518
12MST1R2.19288350
13MAPK111.96233296
14FLT31.91508336
15TYRO31.90678176
16FGFR11.88935866
17PIK3CG1.86409889
18TRIB31.81983450
19PDGFRA1.79698219
20TYK21.70915366
21LATS11.65613985
22DAPK21.62489699
23PTK61.56979675
24NEK91.48744760
25AKT31.47596786
26ABL21.47198054
27FRK1.44888515
28EIF2AK11.32274075
29KDR1.31477014
30FGFR21.30147641
31JAK21.24455661
32WNK11.15178661
33MAP3K71.12904761
34PRKAA21.09788297
35MAPK151.09471622
36NTRK31.09010903
37GRK61.08482085
38ERBB21.07981061
39TBK11.04206367
40MAP3K101.02787326
41PINK11.02287367
42MAP2K31.02127536
43JAK11.00227677
44EEF2K0.99845951
45SIK20.97504576
46MAPK40.94877614
47SMG10.94824757
48MAP3K30.92507268
49MET0.92027515
50MAP3K140.90038781
51EPHA20.89982321
52PRKCZ0.89121722
53EPHB10.87327498
54MAP3K110.86928255
55EPHA30.84220139
56DDR20.83299114
57CDK60.81164716
58STK38L0.81036988
59CDK70.80273135
60DYRK1B0.80156271
61MAPKAPK30.77768106
62PRKACG0.77119015
63SGK10.76508558
64CSNK1E0.75920064
65MAPK120.75019557
66CAMK2G0.73687282
67TIE10.71985470
68RIPK10.71087431
69CAMK1D0.70534596
70CSK0.69337056
71GSK3A0.69095308
72RPS6KB10.66396538
73KSR20.64307973
74PRKAA10.62762648
75MAP2K60.62661852
76PTK20.62535636
77NEK10.61935423
78BRSK10.59961836
79CSNK1D0.59218904
80IRAK30.58029211
81BRSK20.57273260
82TGFBR20.57047001
83SGK30.56301627
84FGFR30.55076474
85MAPK70.52214045
86IKBKE0.51820815
87CSF1R0.50650257
88MAP2K10.50549083
89PRKG10.48478364
90PDPK10.48204940
91PRKCQ0.48113782
92CSNK2A20.46300975
93CSNK1G10.45942860
94CDC42BPA0.45733649
95SRC0.45223233
96TAOK20.44670636
97GRK10.44283783
98MAP3K50.43603032
99RPS6KA30.43400702
100IGF1R0.43173504
101CDK40.42710944
102FGR0.41406192
103BCR0.40729143
104RET0.40122629
105CSNK2A10.39824436
106PRKCG0.39237100
107MTOR0.39186395
108MAP3K130.39106516
109CDK80.38841894
110SCYL20.38821064
111SGK20.38323793
112EPHA40.37451314
113PKN10.37197478
114PBK0.36470202
115ICK0.35631081
116EGFR0.35063036
117PRKACA0.34484299
118PRKCB0.33844262
119MAP3K60.33395679
120MAP3K10.32725958
121MAP2K20.32296848
122CAMK40.31732827
123LMTK20.29312394
124PDK20.29247977
125SGK2230.28399599
126SGK4940.28399599
127PDK10.28330539
128STK390.28278680
129MAPK30.26512558
130PAK30.26351008
131PRKACB0.26245032
132CDK90.25763084
133PRKCA0.25401681
134CSNK1G20.24706686
135MATK0.24483248
136CSNK1G30.23111161
137IRAK10.21940622
138CAMK1G0.21002160
139BMX0.20781318
140LATS20.20694814
141ABL10.19963703
142MAP3K20.19600006
143PIK3CA0.19483616

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.51830647
2Nitrogen metabolism_Homo sapiens_hsa009103.67025716
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.41703873
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.32170030
5Arginine biosynthesis_Homo sapiens_hsa002203.10762796
6Complement and coagulation cascades_Homo sapiens_hsa046102.88732099
7Tryptophan metabolism_Homo sapiens_hsa003802.67029173
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.64039761
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.62655114
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.56432011
11Fatty acid degradation_Homo sapiens_hsa000712.47152737
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.35620421
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.20866026
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.12908759
15Butanoate metabolism_Homo sapiens_hsa006502.11920550
16Peroxisome_Homo sapiens_hsa041462.05229280
17Chemical carcinogenesis_Homo sapiens_hsa052041.94127512
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.90867685
19Histidine metabolism_Homo sapiens_hsa003401.90045795
20Propanoate metabolism_Homo sapiens_hsa006401.89215598
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.86459873
22PPAR signaling pathway_Homo sapiens_hsa033201.85256748
23Staphylococcus aureus infection_Homo sapiens_hsa051501.81805128
24Fatty acid metabolism_Homo sapiens_hsa012121.78420842
25Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.74195266
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.73235936
27Caffeine metabolism_Homo sapiens_hsa002321.68863442
28beta-Alanine metabolism_Homo sapiens_hsa004101.67951828
29Retinol metabolism_Homo sapiens_hsa008301.66306684
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.60890050
31Selenocompound metabolism_Homo sapiens_hsa004501.60489246
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58091805
33Phenylalanine metabolism_Homo sapiens_hsa003601.55994271
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.52035508
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.49555557
36Bile secretion_Homo sapiens_hsa049761.46768433
37Tyrosine metabolism_Homo sapiens_hsa003501.43245218
38Sulfur metabolism_Homo sapiens_hsa009201.36570114
39Pyruvate metabolism_Homo sapiens_hsa006201.35422184
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.33073171
41Fatty acid elongation_Homo sapiens_hsa000621.31503004
42Starch and sucrose metabolism_Homo sapiens_hsa005001.27988117
43Steroid biosynthesis_Homo sapiens_hsa001001.24203616
44Fat digestion and absorption_Homo sapiens_hsa049751.23628190
45Folate biosynthesis_Homo sapiens_hsa007901.23399208
46Biosynthesis of amino acids_Homo sapiens_hsa012301.22376396
47ABC transporters_Homo sapiens_hsa020101.20021378
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.16737790
49Carbon metabolism_Homo sapiens_hsa012001.13554190
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01738004
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01671914
52Vitamin B6 metabolism_Homo sapiens_hsa007501.00135599
53Cyanoamino acid metabolism_Homo sapiens_hsa004600.98266282
54Arginine and proline metabolism_Homo sapiens_hsa003300.96480320
55Sulfur relay system_Homo sapiens_hsa041220.95656546
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87680017
57Vitamin digestion and absorption_Homo sapiens_hsa049770.87068565
58Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.80988326
59Lysine degradation_Homo sapiens_hsa003100.80503007
60One carbon pool by folate_Homo sapiens_hsa006700.77946333
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71420033
62Glutathione metabolism_Homo sapiens_hsa004800.68718588
63Glycerolipid metabolism_Homo sapiens_hsa005610.67325507
64Other glycan degradation_Homo sapiens_hsa005110.66047076
65Pentose phosphate pathway_Homo sapiens_hsa000300.60750781
66Fatty acid biosynthesis_Homo sapiens_hsa000610.51651499
67Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48228591
68Metabolic pathways_Homo sapiens_hsa011000.45680965
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.45649596
70Pertussis_Homo sapiens_hsa051330.41903163
71Prion diseases_Homo sapiens_hsa050200.39266403
72Galactose metabolism_Homo sapiens_hsa000520.27356660
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25944927
74Fructose and mannose metabolism_Homo sapiens_hsa000510.25736252
75Insulin resistance_Homo sapiens_hsa049310.22821886
76N-Glycan biosynthesis_Homo sapiens_hsa005100.21815285
77Linoleic acid metabolism_Homo sapiens_hsa005910.21639292
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.20814380
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.20747519
80Glycerophospholipid metabolism_Homo sapiens_hsa005640.15427155
81Glucagon signaling pathway_Homo sapiens_hsa049220.09982155
82Mineral absorption_Homo sapiens_hsa049780.08755793
83AMPK signaling pathway_Homo sapiens_hsa041520.01350649
84Ether lipid metabolism_Homo sapiens_hsa00565-0.2456288
85Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2413391
86Amoebiasis_Homo sapiens_hsa05146-0.2372805
87Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2252904
88Bladder cancer_Homo sapiens_hsa05219-0.2217780
89Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563-0.2078558
90Circadian rhythm_Homo sapiens_hsa04710-0.2044002
91Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1901288
92Renin-angiotensin system_Homo sapiens_hsa04614-0.1855193
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1839951
94Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1747072
95Hepatitis C_Homo sapiens_hsa05160-0.1703233
96Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1564055
97Regulation of autophagy_Homo sapiens_hsa04140-0.1494136
98Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1489970
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1462508
100African trypanosomiasis_Homo sapiens_hsa05143-0.1370934
101ECM-receptor interaction_Homo sapiens_hsa04512-0.1131114
102Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1056195
103Insulin signaling pathway_Homo sapiens_hsa04910-0.1002867
104Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0934986
105Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0843854
106Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0497230
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0456520
108Sphingolipid metabolism_Homo sapiens_hsa00600-0.0034371

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