AMDHD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1exogenous drug catabolic process (GO:0042738)8.24305068
2omega-hydroxylase P450 pathway (GO:0097267)8.01290872
3epoxygenase P450 pathway (GO:0019373)7.94450051
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.69239759
5L-phenylalanine catabolic process (GO:0006559)7.69239759
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.34870966
7L-phenylalanine metabolic process (GO:0006558)7.34870966
8aromatic amino acid family catabolic process (GO:0009074)6.91615472
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.33929608
10indole-containing compound catabolic process (GO:0042436)6.24530422
11indolalkylamine catabolic process (GO:0046218)6.24530422
12tryptophan catabolic process (GO:0006569)6.24530422
13kynurenine metabolic process (GO:0070189)6.09935017
14bile acid biosynthetic process (GO:0006699)6.02061945
15tryptophan metabolic process (GO:0006568)5.87470659
16glyoxylate metabolic process (GO:0046487)5.84479980
17urea cycle (GO:0000050)5.82300275
18urea metabolic process (GO:0019627)5.82300275
19negative regulation of fibrinolysis (GO:0051918)5.64263788
20high-density lipoprotein particle remodeling (GO:0034375)5.59763742
21alpha-linolenic acid metabolic process (GO:0036109)5.56232258
22drug metabolic process (GO:0017144)5.49585641
23oxidative demethylation (GO:0070989)5.49238789
24cysteine metabolic process (GO:0006534)5.49172434
25sulfur amino acid catabolic process (GO:0000098)5.47714657
26regulation of fibrinolysis (GO:0051917)5.45479546
27protein carboxylation (GO:0018214)5.39348362
28peptidyl-glutamic acid carboxylation (GO:0017187)5.39348362
29complement activation, alternative pathway (GO:0006957)5.37309671
30nitrogen cycle metabolic process (GO:0071941)5.35307596
31regulation of protein activation cascade (GO:2000257)5.34867740
32intestinal cholesterol absorption (GO:0030299)5.26080797
33serine family amino acid catabolic process (GO:0009071)5.22765352
34bile acid metabolic process (GO:0008206)5.12888313
35opsonization (GO:0008228)5.04681731
36aromatic amino acid family metabolic process (GO:0009072)5.02616082
37regulation of complement activation (GO:0030449)4.99186823
38regulation of plasminogen activation (GO:0010755)4.96422096
39ethanol metabolic process (GO:0006067)4.95406458
40homocysteine metabolic process (GO:0050667)4.94666475
41acute-phase response (GO:0006953)4.91868234
42fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.90605181
43tyrosine metabolic process (GO:0006570)4.89574965
44regulation of cholesterol esterification (GO:0010872)4.87688993
45regulation of humoral immune response (GO:0002920)4.87197426
46reverse cholesterol transport (GO:0043691)4.87065450
47regulation of triglyceride catabolic process (GO:0010896)4.83790455
48protein-lipid complex remodeling (GO:0034368)4.79841603
49macromolecular complex remodeling (GO:0034367)4.79841603
50plasma lipoprotein particle remodeling (GO:0034369)4.79841603
51* alpha-amino acid catabolic process (GO:1901606)4.65923043
52amino-acid betaine metabolic process (GO:0006577)4.63397242
53acylglycerol homeostasis (GO:0055090)4.62707573
54triglyceride homeostasis (GO:0070328)4.62707573
55lysine metabolic process (GO:0006553)4.59855239
56lysine catabolic process (GO:0006554)4.59855239
57negative regulation of protein activation cascade (GO:2000258)4.59256782
58negative regulation of cholesterol transport (GO:0032375)4.58742471
59negative regulation of sterol transport (GO:0032372)4.58742471
60phospholipid efflux (GO:0033700)4.56759337
61killing of cells in other organism involved in symbiotic interaction (GO:0051883)4.54293953
62disruption of cells of other organism involved in symbiotic interaction (GO:0051818)4.54293953
63negative regulation of hemostasis (GO:1900047)4.50687199
64negative regulation of blood coagulation (GO:0030195)4.50687199
65glycine metabolic process (GO:0006544)4.49021396
66coenzyme catabolic process (GO:0009109)4.45420293
67bile acid and bile salt transport (GO:0015721)4.43629780
68cellular ketone body metabolic process (GO:0046950)4.43308515
69indolalkylamine metabolic process (GO:0006586)4.42404567
70plasma lipoprotein particle clearance (GO:0034381)4.40405882
71positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.40191896
72phenylpropanoid metabolic process (GO:0009698)4.35645640
73cellular biogenic amine catabolic process (GO:0042402)4.33851902
74amine catabolic process (GO:0009310)4.33851902
75* cellular amino acid catabolic process (GO:0009063)4.28596308
76serine family amino acid metabolic process (GO:0009069)4.25094654
77cellular glucuronidation (GO:0052695)4.25012430
78cholesterol efflux (GO:0033344)4.24466255
79S-adenosylmethionine metabolic process (GO:0046500)4.15870605
80benzene-containing compound metabolic process (GO:0042537)4.14647685
81cellular modified amino acid catabolic process (GO:0042219)4.12891656
82ethanol oxidation (GO:0006069)4.11506954
83serine family amino acid biosynthetic process (GO:0009070)4.11265073
84arginine metabolic process (GO:0006525)4.11051983
85dicarboxylic acid biosynthetic process (GO:0043650)4.08895585
86aldehyde catabolic process (GO:0046185)4.07905684
87low-density lipoprotein particle remodeling (GO:0034374)4.07459423
88* glutamate metabolic process (GO:0006536)4.05273683
89fibrinolysis (GO:0042730)4.03295296
90negative regulation of coagulation (GO:0050819)4.02870311
91plasma lipoprotein particle assembly (GO:0034377)4.02470246
92negative regulation of wound healing (GO:0061045)3.96191398
93positive regulation of blood coagulation (GO:0030194)3.91671032
94positive regulation of hemostasis (GO:1900048)3.91671032
95blood coagulation, intrinsic pathway (GO:0007597)3.87526271
96* imidazole-containing compound metabolic process (GO:0052803)3.86117052
97ketone body metabolic process (GO:1902224)3.84575404
98cofactor catabolic process (GO:0051187)3.83791401
99drug catabolic process (GO:0042737)3.83389909
100positive regulation of fatty acid biosynthetic process (GO:0045723)3.82226808
101very-low-density lipoprotein particle assembly (GO:0034379)3.78198295
102complement activation, classical pathway (GO:0006958)3.77193469
103uronic acid metabolic process (GO:0006063)3.76920439
104glucuronate metabolic process (GO:0019585)3.76920439
105flavonoid metabolic process (GO:0009812)3.76741983
106alkaloid metabolic process (GO:0009820)3.75871516
107positive regulation of triglyceride lipase activity (GO:0061365)3.75141402
108positive regulation of lipoprotein lipase activity (GO:0051006)3.75141402
109regulation of bile acid biosynthetic process (GO:0070857)3.74523001
110cholesterol homeostasis (GO:0042632)3.74382970
111complement activation (GO:0006956)3.74085525
112* organic acid catabolic process (GO:0016054)3.73890360
113* carboxylic acid catabolic process (GO:0046395)3.73890360
114regulation of apoptotic cell clearance (GO:2000425)3.73525791
115protein activation cascade (GO:0072376)3.73130163
116negative regulation of lipase activity (GO:0060192)3.73061184
117phospholipid homeostasis (GO:0055091)3.71926142
118positive regulation of lipid catabolic process (GO:0050996)3.71720701
119acetyl-CoA metabolic process (GO:0006084)3.69222126
120sterol homeostasis (GO:0055092)3.67970191
121cytolysis (GO:0019835)3.67609935
122regulation of cholesterol homeostasis (GO:2000188)3.64758622
123negative regulation of complement activation (GO:0045916)3.64347620
124short-chain fatty acid metabolic process (GO:0046459)3.64226989
125plasma lipoprotein particle organization (GO:0071827)3.64204028
126acute inflammatory response (GO:0002526)3.63946121
127NAD biosynthetic process (GO:0009435)3.61343677
128protein-lipid complex assembly (GO:0065005)3.60502624
129positive regulation of coagulation (GO:0050820)3.57395834
130nicotinamide nucleotide biosynthetic process (GO:0019359)3.56136201
131protein-lipid complex subunit organization (GO:0071825)3.51046660
132response to mercury ion (GO:0046689)3.37485196
133sodium-independent organic anion transport (GO:0043252)3.33611217

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.41853746
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.21083662
3EGR1_23403033_ChIP-Seq_LIVER_Mouse7.07631529
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.51182994
5* FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.23057534
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.13637594
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.78073419
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.04328027
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.01974787
10TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.09162850
11TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.08124770
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse12.0497707
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.98617467
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.94421591
15MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.68719468
16P68_20966046_ChIP-Seq_HELA_Human1.66430848
17ELF1_20517297_ChIP-Seq_JURKAT_Human1.61846845
18* FOXA2_19822575_ChIP-Seq_HepG2_Human1.58960825
19VDR_21846776_ChIP-Seq_THP-1_Human1.57680479
20HTT_18923047_ChIP-ChIP_STHdh_Human1.57348643
21BCOR_27268052_Chip-Seq_Bcells_Human1.53702619
22CLOCK_20551151_ChIP-Seq_293T_Human1.51786106
23BCL6_27268052_Chip-Seq_Bcells_Human1.49682424
24SMC4_20622854_ChIP-Seq_HELA_Human1.49620076
25GATA1_22025678_ChIP-Seq_K562_Human1.45053223
26TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44818497
27E2F1_20622854_ChIP-Seq_HELA_Human1.40046865
28* HNF4A_19822575_ChIP-Seq_HepG2_Human1.39788301
29RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29220222
30PHF8_20622854_ChIP-Seq_HELA_Human1.28416827
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.28135529
32TET1_21451524_ChIP-Seq_MESCs_Mouse1.23044387
33* ELK3_25401928_ChIP-Seq_HUVEC_Human1.21122213
34RXRA_24833708_ChIP-Seq_LIVER_Mouse1.20609900
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19888370
36CTCF_27219007_Chip-Seq_Bcells_Human1.19110605
37CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.18507309
38STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17618305
39TCF7_22412390_ChIP-Seq_EML_Mouse1.17267678
40RAC3_21632823_ChIP-Seq_H3396_Human1.15566025
41SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15147909
42KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10820718
43RACK7_27058665_Chip-Seq_MCF-7_Human1.09972047
44SRY_22984422_ChIP-ChIP_TESTIS_Rat1.09594212
45E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.09533467
46SA1_27219007_Chip-Seq_ERYTHROID_Human1.09380299
47MYC_22102868_ChIP-Seq_BL_Human1.08095343
48SA1_27219007_Chip-Seq_Bcells_Human1.06653836
49ESR1_15608294_ChIP-ChIP_MCF-7_Human1.06482194
50YY1_22570637_ChIP-Seq_MALME-3M_Human1.04775523
51IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.04431229
52CTCF_20526341_ChIP-Seq_ESCs_Human1.03995729
53P300_27268052_Chip-Seq_Bcells_Human1.03767819
54GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.03056649
55STAT6_21828071_ChIP-Seq_BEAS2B_Human1.02585061
56SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02443934
57ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00539498
58KDM2B_26808549_Chip-Seq_SUP-B15_Human1.00380466
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96912633
60CTCF_27219007_Chip-Seq_ERYTHROID_Human0.96263723
61SPI1_20517297_ChIP-Seq_HL60_Human0.96044413
62EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94910878
63ERA_21632823_ChIP-Seq_H3396_Human0.94700161
64PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93889517
65P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.93716541
66PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91202968
67SOX2_27498859_Chip-Seq_STOMACH_Mouse0.90947939
68TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.90130499
69DNAJC2_21179169_ChIP-ChIP_NT2_Human0.89773476
70IRF8_22096565_ChIP-ChIP_GC-B_Human0.86798088
71JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.86664847
72EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.86645484
73VDR_24763502_ChIP-Seq_THP-1_Human0.86575108
74TP63_22573176_ChIP-Seq_HFKS_Human0.85714449
75MAF_26560356_Chip-Seq_TH1_Human0.85576400
76ETS1_21867929_ChIP-Seq_TH2_Mouse0.85568169
77PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.85135003
78SOX2_21211035_ChIP-Seq_LN229_Human0.84464332
79PU.1_20513432_ChIP-Seq_Bcells_Mouse0.84237350
80BRD4_27068464_Chip-Seq_AML-cells_Mouse0.84198478
81CTCF_21964334_Chip-Seq_Bcells_Human0.83454519
82MAF_26560356_Chip-Seq_TH2_Human0.83184910
83AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82998598
84RARG_19884340_ChIP-ChIP_MEFs_Mouse0.82069648
85ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.81969418
86SCL_19346495_ChIP-Seq_HPC-7_Human0.80310586
87GATA4_25053715_ChIP-Seq_YYC3_Human0.79632232
88PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78956451
89EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.78669832
90CTCF_21964334_ChIP-Seq_BJAB-B_Human0.78521482
91ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.78220827
92KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77877097
93* CREB1_26743006_Chip-Seq_LNCaP_Human0.77313092
94KDM2B_26808549_Chip-Seq_DND41_Human0.77048557
95RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.76287970
96SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75847635
97SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.75447224
98BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.75200107
99RARA_24833708_ChIP-Seq_LIVER_Mouse0.74248482
100ZNF263_19887448_ChIP-Seq_K562_Human0.74143189
101Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.71716491
102CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.70231601
103SALL4_18804426_ChIP-ChIP_XEN_Mouse0.66061478
104AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.65750560
105RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.64550886
106RARB_24833708_ChIP-Seq_LIVER_Mouse0.64264775
107ESR2_21235772_ChIP-Seq_MCF-7_Human0.64200280
108NRF2_20460467_ChIP-Seq_MEFs_Mouse0.63979223
109NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.63979223
110NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.62827254
111RAD21_21589869_ChIP-Seq_MESCs_Mouse0.61505807
112NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.60016336
113BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.59973893
114CEBPB_22108803_ChIP-Seq_LS180_Human0.56920152
115NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.56051489
116EGR1_19032775_ChIP-ChIP_M12_Human0.55800369
117LXR_22292898_ChIP-Seq_THP-1_Human0.53566756
118FOXA1_25552417_ChIP-Seq_VCAP_Human0.53084311
119PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.52083167
120AR_20517297_ChIP-Seq_VCAP_Human0.51979474
121MYC_19915707_ChIP-ChIP_AK7_Human0.51861048
122FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.51817271
123STAT3_1855785_ChIP-Seq_MESCs_Mouse0.51566725
124FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.50935888
125E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.48995012
126ESET_19884257_ChIP-Seq_ESCs_Mouse0.48414870
127CBP_21632823_ChIP-Seq_H3396_Human0.47416837
128P53_21459846_ChIP-Seq_SAOS-2_Human0.47212430
129TAF15_26573619_Chip-Seq_HEK293_Human0.46391818
130PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.45170821
131* STAT1_17558387_ChIP-Seq_HELA_Human0.44831439
132CDX2_20551321_ChIP-Seq_CACO-2_Human0.44009182
133PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.43698368
134PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.42786970
135FOXO3_23340844_ChIP-Seq_DLD1_Human0.42545523
136FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.42526065
137GATA1_19941827_ChIP-Seq_MEL_Mouse0.42451652
138GATA1_19941826_ChIP-Seq_K562_Human0.42238616
139TAF2_19829295_ChIP-Seq_ESCs_Human0.42206913
140SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41811577
141FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.41774767
142ESR1_21235772_ChIP-Seq_MCF-7_Human0.41507239
143GATA2_19941826_ChIP-Seq_K562_Human0.39455051
144BCAT_22108803_ChIP-Seq_LS180_Human0.39272207
145ERG_21242973_ChIP-ChIP_JURKAT_Human0.39227593
146ESR1_20079471_ChIP-ChIP_T-47D_Human0.39063737
147MYC_27129775_Chip-Seq_CORNEA_Mouse0.38506932
148PPAR_26484153_Chip-Seq_NCI-H1993_Human0.38201943
149GATA6_25053715_ChIP-Seq_YYC3_Human0.38025355
150* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.37875650
151STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.37444130
152SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.36033608
153SPI1_26923725_Chip-Seq_HPCs_Mouse0.35576478
154CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.34204824
155NCOR_22424771_ChIP-Seq_293T_Human0.33907481
156* LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.33453365
157ERG_20517297_ChIP-Seq_VCAP_Human0.32603590
158BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.32244744
159OCT4_20526341_ChIP-Seq_ESCs_Human0.32086514

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.29475894
2MP0005360_urolithiasis7.60580059
3MP0005085_abnormal_gallbladder_physiolo6.48186452
4MP0005365_abnormal_bile_salt6.18870648
5MP0008875_abnormal_xenobiotic_pharmacok5.09562084
6MP0003806_abnormal_nucleotide_metabolis4.30473271
7MP0003252_abnormal_bile_duct3.94010845
8MP0010329_abnormal_lipoprotein_level3.59010195
9MP0009840_abnormal_foam_cell3.27439703
10MP0005083_abnormal_biliary_tract3.04309534
11MP0003195_calcinosis2.90273520
12MP0005332_abnormal_amino_acid2.77865176
13MP0001666_abnormal_nutrient_absorption2.58923293
14MP0003191_abnormal_cellular_cholesterol2.28013484
15MP0000609_abnormal_liver_physiology2.16125627
16MP0004019_abnormal_vitamin_homeostasis2.11160067
17MP0002118_abnormal_lipid_homeostasis2.09693435
18MP0002138_abnormal_hepatobiliary_system1.99686300
19MP0003868_abnormal_feces_composition1.93329995
20MP0005319_abnormal_enzyme/_coenzyme1.82832341
21MP0001764_abnormal_homeostasis1.70238403
22MP0009697_abnormal_copulation1.62092335
23MP0005584_abnormal_enzyme/coenzyme_acti1.56788082
24MP0005451_abnormal_body_composition1.45913350
25MP0003011_delayed_dark_adaptation1.37768784
26MP0005058_abnormal_lysosome_morphology1.33521087
27MP0003186_abnormal_redox_activity1.28105028
28MP0003656_abnormal_erythrocyte_physiolo1.26072115
29MP0009643_abnormal_urine_homeostasis1.21922055
30MP0000598_abnormal_liver_morphology1.17912643
31MP0003705_abnormal_hypodermis_morpholog1.17624299
32MP0005647_abnormal_sex_gland1.14125183
33MP0002254_reproductive_system_inflammat1.09312980
34MP0000604_amyloidosis1.07737175
35MP0009764_decreased_sensitivity_to1.04626950
36MP0009763_increased_sensitivity_to1.01778150
37MP0010368_abnormal_lymphatic_system0.94650592
38MP0005636_abnormal_mineral_homeostasis0.90406037
39MP0008469_abnormal_protein_level0.89005589
40MP0005410_abnormal_fertilization0.88586452
41MP0009642_abnormal_blood_homeostasis0.86776850
42MP0005408_hypopigmentation0.86465699
43MP0006036_abnormal_mitochondrial_physio0.81431046
44MP0005376_homeostasis/metabolism_phenot0.81245624
45MP0001915_intracranial_hemorrhage0.80427499
46MP0005377_hearing/vestibular/ear_phenot0.79755548
47MP0003878_abnormal_ear_physiology0.79755548
48MP0002876_abnormal_thyroid_physiology0.79736016
49MP0003172_abnormal_lysosome_physiology0.78884785
50MP0009785_altered_susceptibility_to0.78264560
51MP0009765_abnormal_xenobiotic_induced0.77900376
52MP0003879_abnormal_hair_cell0.77549316
53MP0002078_abnormal_glucose_homeostasis0.76975449
54MP0005670_abnormal_white_adipose0.75920700
55MP0005084_abnormal_gallbladder_morpholo0.75239094
56MP0002249_abnormal_larynx_morphology0.72895708
57MP0002971_abnormal_brown_adipose0.71836578
58MP0005220_abnormal_exocrine_pancreas0.71205844
59MP0001545_abnormal_hematopoietic_system0.69313156
60MP0005397_hematopoietic_system_phenotyp0.69313156
61MP0005334_abnormal_fat_pad0.68695345
62MP0004130_abnormal_muscle_cell0.67701412
63MP0001661_extended_life_span0.66866813
64MP0005535_abnormal_body_temperature0.66798112
65MP0003690_abnormal_glial_cell0.66535892
66MP0005266_abnormal_metabolism0.66012554
67MP0009053_abnormal_anal_canal0.64771211
68MP0002282_abnormal_trachea_morphology0.62861819
69MP0003329_amyloid_beta_deposits0.62582044
70MP0009333_abnormal_splenocyte_physiolog0.62553155
71MP0000639_abnormal_adrenal_gland0.61443979
72MP0002089_abnormal_postnatal_growth/wei0.60776115
73MP0002419_abnormal_innate_immunity0.58355772
74MP0003303_peritoneal_inflammation0.58298283
75MP0005025_abnormal_response_to0.57573799
76MP0001756_abnormal_urination0.57350124
77MP0001986_abnormal_taste_sensitivity0.57347889
78MP0000685_abnormal_immune_system0.57122543
79MP0006035_abnormal_mitochondrial_morpho0.56928280
80MP0005023_abnormal_wound_healing0.56724023
81MP0005448_abnormal_energy_balance0.54808027
82MP0005464_abnormal_platelet_physiology0.53884023
83MP0002933_joint_inflammation0.51713238
84MP0002822_catalepsy0.51120755
85MP0002332_abnormal_exercise_endurance0.49772163
86MP0000678_abnormal_parathyroid_gland0.48073105
87MP0005395_other_phenotype0.48070690
88MP0003638_abnormal_response/metabolism_0.46819878
89MP0008874_decreased_physiological_sensi0.45420654
90MP0003718_maternal_effect0.45371094
91MP0000566_synostosis0.45364558
92MP0002928_abnormal_bile_duct0.45237500
93MP0008873_increased_physiological_sensi0.44327992
94MP0002136_abnormal_kidney_physiology0.43991469
95MP0003724_increased_susceptibility_to0.43723540
96MP0004381_abnormal_hair_follicle0.43667804
97MP0003436_decreased_susceptibility_to0.43453399
98MP0005409_darkened_coat_color0.43158557
99MP0004782_abnormal_surfactant_physiolog0.41274207
100MP0003075_altered_response_to0.40820475
101MP0002837_dystrophic_cardiac_calcinosis0.40286432
102MP0003953_abnormal_hormone_level0.39839638
103MP0005076_abnormal_cell_differentiation0.39591880
104MP0005248_abnormal_Harderian_gland0.39207285
105MP0010155_abnormal_intestine_physiology0.39048280
106MP0005375_adipose_tissue_phenotype0.38916397
107MP0008260_abnormal_autophagy0.38431023
108MP0005166_decreased_susceptibility_to0.37843757
109MP0008872_abnormal_physiological_respon0.36949424
110MP0009672_abnormal_birth_weight0.36433211
111MP0000858_altered_metastatic_potential0.36419733
112MP0001851_eye_inflammation0.34741808
113MP0005666_abnormal_adipose_tissue0.34469327
114MP0000579_abnormal_nail_morphology0.34305625
115MP0006082_CNS_inflammation0.33682396
116MP0002796_impaired_skin_barrier0.32807868
117MP0000249_abnormal_blood_vessel0.32422412
118MP0004883_abnormal_blood_vessel0.32390909
119MP0000230_abnormal_systemic_arterial0.31985466
120MP0001853_heart_inflammation0.31962515
121MP0001243_abnormal_dermal_layer0.31955053
122MP0009115_abnormal_fat_cell0.31884230
123MP0009384_cardiac_valve_regurgitation0.31767812
124MP0002168_other_aberrant_phenotype0.30809913
125MP0002970_abnormal_white_adipose0.30035794
126MP0001845_abnormal_inflammatory_respons0.28514095
127MP0001881_abnormal_mammary_gland0.27501981
128MP0002132_abnormal_respiratory_system0.25290068
129MP0005164_abnormal_response_to0.25279005
130MP0002060_abnormal_skin_morphology0.23620966
131MP0002090_abnormal_vision0.22353669

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.50643201
2Deep venous thrombosis (HP:0002625)7.45415735
3Intrahepatic cholestasis (HP:0001406)7.39448905
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.78720185
5Prolonged partial thromboplastin time (HP:0003645)6.61728062
6Hypobetalipoproteinemia (HP:0003563)6.46188481
7Xanthomatosis (HP:0000991)6.31626095
8Hyperlipoproteinemia (HP:0010980)5.61234902
9Complement deficiency (HP:0004431)5.36043523
10Joint hemorrhage (HP:0005261)4.84143721
11Hypolipoproteinemia (HP:0010981)4.81130206
12Hyperammonemia (HP:0001987)4.62505196
13Epidermoid cyst (HP:0200040)4.57981700
14Abnormality of the common coagulation pathway (HP:0010990)4.45824695
15Hyperglycinemia (HP:0002154)4.42682228
16Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.40388500
17Abnormality of methionine metabolism (HP:0010901)4.37996303
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.32805208
19Ketosis (HP:0001946)4.23493121
20Abnormality of glutamine family amino acid metabolism (HP:0010902)4.19879626
21Hypoalphalipoproteinemia (HP:0003233)4.19281232
22Abnormality of aspartate family amino acid metabolism (HP:0010899)4.18609183
23Fat malabsorption (HP:0002630)4.15047749
24Hyperglycinuria (HP:0003108)3.92527532
25Abnormality of pyrimidine metabolism (HP:0004353)3.91866649
26Abnormality of complement system (HP:0005339)3.90995223
27Abnormality of serine family amino acid metabolism (HP:0010894)3.90766352
28Abnormality of glycine metabolism (HP:0010895)3.90766352
29Hypoglycemic coma (HP:0001325)3.78947581
30Abnormality of the intrinsic pathway (HP:0010989)3.77494105
31Conjugated hyperbilirubinemia (HP:0002908)3.77443833
32Hypercholesterolemia (HP:0003124)3.64816270
33Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.39053120
34Hyperbilirubinemia (HP:0002904)3.36098455
35Abnormality of fatty-acid metabolism (HP:0004359)3.32792360
36Steatorrhea (HP:0002570)3.11747471
37Delayed CNS myelination (HP:0002188)3.09966567
38Abnormality of serum amino acid levels (HP:0003112)3.09354361
39Abnormality of nucleobase metabolism (HP:0010932)3.06468501
40Purpura (HP:0000979)3.03235785
41Spontaneous abortion (HP:0005268)3.02574438
42Hepatocellular carcinoma (HP:0001402)3.00569482
43Myocardial infarction (HP:0001658)2.99223976
44Hypochromic microcytic anemia (HP:0004840)2.97435009
45Ketoacidosis (HP:0001993)2.96174322
46Skin nodule (HP:0200036)2.82838651
47Metabolic acidosis (HP:0001942)2.75110364
48Systemic lupus erythematosus (HP:0002725)2.74392630
49Abnormality of purine metabolism (HP:0004352)2.63769428
50Lethargy (HP:0001254)2.60265310
51Acanthocytosis (HP:0001927)2.59836601
52Vascular calcification (HP:0004934)2.57453946
53Increased serum ferritin (HP:0003281)2.55331890
54Dicarboxylic aciduria (HP:0003215)2.54844335
55Abnormality of dicarboxylic acid metabolism (HP:0010995)2.54844335
56Abnormal gallbladder morphology (HP:0012437)2.49374060
57Spastic diplegia (HP:0001264)2.46934668
58Mitral stenosis (HP:0001718)2.46463343
59Cerebral edema (HP:0002181)2.45472760
60Glomerulonephritis (HP:0000099)2.43223704
61Cholelithiasis (HP:0001081)2.42440726
62Epistaxis (HP:0000421)2.42020217
63Gout (HP:0001997)2.41356170
64Hypoglycemic seizures (HP:0002173)2.40936035
65Neonatal onset (HP:0003623)2.38089497
66Irritability (HP:0000737)2.36483700
67Recurrent gram-negative bacterial infections (HP:0005420)2.34967973
68Amyloidosis (HP:0011034)2.34231725
69Cholecystitis (HP:0001082)2.31593412
70Abnormal gallbladder physiology (HP:0012438)2.31593412
71Cardiovascular calcification (HP:0011915)2.28138439
72Malnutrition (HP:0004395)2.25842378
73Osteomalacia (HP:0002749)2.24491168
74Gingival bleeding (HP:0000225)2.22452309
75Neonatal hypoglycemia (HP:0001998)2.21138043
76Elevated alkaline phosphatase (HP:0003155)2.18570953
77Esophageal varix (HP:0002040)2.18385465
78Menorrhagia (HP:0000132)2.14973560
79Pancreatitis (HP:0001733)2.14215564
80Joint swelling (HP:0001386)2.13878884
81Sensorimotor neuropathy (HP:0007141)2.12953876
82Brushfield spots (HP:0001088)2.12825873
83Thrombophlebitis (HP:0004418)2.10925715
84Enlarged kidneys (HP:0000105)2.09556729
85Abnormality of alkaline phosphatase activity (HP:0004379)2.07607113
86Late onset (HP:0003584)2.06314700
87Vomiting (HP:0002013)2.05394173
88Poikilocytosis (HP:0004447)2.04011125
89Fair hair (HP:0002286)2.03732286
90Abnormality of the gallbladder (HP:0005264)2.02355159
91Hemorrhage of the eye (HP:0011885)2.00871555
92Opisthotonus (HP:0002179)2.00199736
93Abnormality of the Achilles tendon (HP:0005109)2.00182796
94Generalized aminoaciduria (HP:0002909)1.98650982
95Cerebral palsy (HP:0100021)1.98072962
96Hyperinsulinemic hypoglycemia (HP:0000825)1.95329028
97Abnormality of iron homeostasis (HP:0011031)1.92228127
98Rickets (HP:0002748)1.91858472
99Abnormality of transition element cation homeostasis (HP:0011030)1.88747090
100Abnormal cartilage morphology (HP:0002763)1.87791695
101Renal cortical cysts (HP:0000803)1.86156787
102Hypophosphatemic rickets (HP:0004912)1.85741929
103Hydroxyprolinuria (HP:0003080)1.83529266
104Abnormality of proline metabolism (HP:0010907)1.83529266
105Alkalosis (HP:0001948)1.83515102
106Elevated hepatic transaminases (HP:0002910)1.81700449
107Abnormal enzyme/coenzyme activity (HP:0012379)1.80811889
108Reduced antithrombin III activity (HP:0001976)1.80156952
109Gangrene (HP:0100758)1.79837065
110Status epilepticus (HP:0002133)1.77974740
111Hypertriglyceridemia (HP:0002155)1.75151515
112Arthropathy (HP:0003040)1.74725380
113Abnormal platelet function (HP:0011869)1.73514632
114Impaired platelet aggregation (HP:0003540)1.73514632
115Nephritis (HP:0000123)1.72759232
116Abnormality of vitamin metabolism (HP:0100508)1.72105868
117Pulmonary embolism (HP:0002204)1.71605403
118Abnormality of polysaccharide metabolism (HP:0011012)1.70635013
119Abnormality of glycosaminoglycan metabolism (HP:0004371)1.70635013
120Abnormality of mucopolysaccharide metabolism (HP:0011020)1.70635013
121Urinary glycosaminoglycan excretion (HP:0003541)1.69895685
122Mucopolysacchariduria (HP:0008155)1.69895685
123Increased mean platelet volume (HP:0011877)1.62780751
124Reticulocytosis (HP:0001923)1.60539105
125Abnormal platelet volume (HP:0011876)1.60000011
126Anorexia (HP:0002039)1.54039587
127Orchitis (HP:0100796)1.52580488
128Hypophosphatemia (HP:0002148)1.50980722
129Potter facies (HP:0002009)1.48117815
130Facial shape deformation (HP:0011334)1.48117815
131Prolonged bleeding time (HP:0003010)1.45817945

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.12739527
2FGFR44.73515739
3SIK14.61780188
4ERN14.22547180
5TAOK33.11440095
6INSRR2.99446999
7ERBB42.91948644
8CDK122.34099225
9MAP2K42.30358244
10PKN22.26023003
11MAP4K12.15866585
12MST1R2.15385615
13FLT31.99633875
14MAPK111.91398045
15AKT31.90157988
16PIK3CG1.81152933
17TYK21.77388183
18TRIB31.72851840
19TNK21.64708617
20LATS11.60673382
21DAPK21.55229356
22PTK61.51546119
23ABL21.47508801
24FGFR21.43940456
25NEK91.38189126
26BLK1.37875297
27ZAP701.36896977
28FRK1.36378080
29PRPF4B1.34251699
30EPHA21.31311701
31KDR1.30402204
32TESK21.30016652
33JAK21.25133077
34MAP3K71.22170534
35SIK21.19436743
36WNK41.19060696
37DDR21.13259675
38PINK11.12275925
39PRKAA21.11044922
40TBK11.10517509
41MAP3K101.09422817
42GRK61.08042548
43MAP3K141.07436578
44ERBB21.04676096
45JAK11.04139220
46MAP2K31.02758324
47MAPK40.98512337
48SMG10.98062337
49MAPK150.95006308
50PRKCZ0.92198613
51EPHB10.88732906
52MET0.87103957
53MAPKAPK30.82812684
54STK38L0.82465554
55MAPK120.82014814
56CDK60.81193912
57EPHA30.80904504
58IKBKB0.79807106
59MAP3K30.78482212
60CHUK0.78146511
61STK380.77583879
62MARK20.77321856
63TIE10.76968215
64CDC42BPA0.76641793
65EEF2K0.75006880
66PRKACG0.74894375
67MAP3K110.74303808
68MAP3K20.73444255
69DYRK1B0.71897291
70CSK0.71689622
71CAMK2G0.70839453
72MAP2K60.65363745
73IRAK30.64999094
74GSK3A0.64954498
75PRKAA10.63902091
76CDK70.63534753
77SGK30.62260383
78FGFR30.61829657
79CSF1R0.61312805
80CAMK1D0.61220254
81IKBKE0.59809980
82PRKD20.59488839
83TESK10.59136231
84MAPK70.58514283
85RIPK10.57913899
86TGFBR20.57359660
87PTK20.56976162
88PRKCQ0.54506954
89CSNK1G10.53806308
90TAOK10.53752599
91MAP3K130.51458666
92KIT0.50903218
93RPS6KA60.50367596
94RPS6KC10.50326001
95RPS6KL10.50326001
96PDPK10.50155127
97TTN0.48061897
98LMTK20.47130124
99GRK10.46937597
100MAP4K20.46883487
101SYK0.46529324
102SGK20.45331087
103EPHA40.44907770
104IGF1R0.44540003
105KSR20.43960604
106LCK0.43240008
107HIPK20.42898280
108CDK40.42114701
109TAOK20.42022747
110HCK0.41637366
111MAPK30.41327794
112PKN10.41185236
113PIK3CA0.41145619
114RET0.40081766
115BTK0.39763475
116PRKCG0.39377824
117MAP3K50.39165899
118MAP2K10.39120557
119MELK0.38521129
120JAK30.37994354
121ICK0.37587056
122IRAK40.37179107
123RPS6KA10.36288172
124PBK0.35923511
125MTOR0.34712300
126MAPK10.34558542
127CSNK1G20.34043683
128EGFR0.33951228
129PRKG20.33633258
130CSNK1G30.32251278
131PDK10.31405477
132CAMK40.31302885
133SGK2230.30127870
134SGK4940.30127870
135MAP3K60.30096112
136MAP3K10.28379972
137IRAK10.25400686
138PRKCA0.25288671
139LATS20.23864632
140IRAK20.23518783
141CSNK1A1L0.22812574
142ABL10.20790145
143MAP2K20.20466587
144BMX0.19086359
145CAMK1G0.18889943
146ITK0.18767906

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.56916845
2Nitrogen metabolism_Homo sapiens_hsa009103.68033716
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.43646944
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.34393985
5Arginine biosynthesis_Homo sapiens_hsa002203.14439277
6Complement and coagulation cascades_Homo sapiens_hsa046102.78256216
7Tryptophan metabolism_Homo sapiens_hsa003802.69340857
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.65738666
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.63849465
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.59003162
11Fatty acid degradation_Homo sapiens_hsa000712.47177191
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.37227611
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.24193091
14Butanoate metabolism_Homo sapiens_hsa006502.12730170
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.12199147
16Peroxisome_Homo sapiens_hsa041462.08018837
17Chemical carcinogenesis_Homo sapiens_hsa052041.94736322
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.91873663
19Steroid hormone biosynthesis_Homo sapiens_hsa001401.91405276
20Propanoate metabolism_Homo sapiens_hsa006401.90709490
21PPAR signaling pathway_Homo sapiens_hsa033201.84794003
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.78813922
23Fatty acid metabolism_Homo sapiens_hsa012121.77581981
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.77554756
25Staphylococcus aureus infection_Homo sapiens_hsa051501.76822221
26Caffeine metabolism_Homo sapiens_hsa002321.75605250
27* Histidine metabolism_Homo sapiens_hsa003401.70426688
28beta-Alanine metabolism_Homo sapiens_hsa004101.70387724
29Retinol metabolism_Homo sapiens_hsa008301.69530520
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.65982177
31Selenocompound metabolism_Homo sapiens_hsa004501.61331340
32Phenylalanine metabolism_Homo sapiens_hsa003601.58654926
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.57941329
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.52365039
352-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.51397709
36Bile secretion_Homo sapiens_hsa049761.48699171
37Tyrosine metabolism_Homo sapiens_hsa003501.46666199
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.36611767
39Sulfur metabolism_Homo sapiens_hsa009201.35980245
40Pyruvate metabolism_Homo sapiens_hsa006201.34539873
41Fatty acid elongation_Homo sapiens_hsa000621.31648286
42Starch and sucrose metabolism_Homo sapiens_hsa005001.26586846
43Folate biosynthesis_Homo sapiens_hsa007901.22532282
44Biosynthesis of amino acids_Homo sapiens_hsa012301.22520288
45Steroid biosynthesis_Homo sapiens_hsa001001.21461005
46ABC transporters_Homo sapiens_hsa020101.20527924
47Fat digestion and absorption_Homo sapiens_hsa049751.14511352
48Carbon metabolism_Homo sapiens_hsa012001.12074739
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.06378626
50Cyanoamino acid metabolism_Homo sapiens_hsa004600.98917811
51Maturity onset diabetes of the young_Homo sapiens_hsa049500.97469010
52Arginine and proline metabolism_Homo sapiens_hsa003300.96931281
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.96083334
54Vitamin B6 metabolism_Homo sapiens_hsa007500.95052830
55Sulfur relay system_Homo sapiens_hsa041220.94643019
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86955683
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.84493220
58Vitamin digestion and absorption_Homo sapiens_hsa049770.84237358
59Lysine degradation_Homo sapiens_hsa003100.80586289
60One carbon pool by folate_Homo sapiens_hsa006700.79070413
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68934433
62Other glycan degradation_Homo sapiens_hsa005110.68357666
63Glycerolipid metabolism_Homo sapiens_hsa005610.65077928
64Glutathione metabolism_Homo sapiens_hsa004800.64412828
65Pentose phosphate pathway_Homo sapiens_hsa000300.56534913
66Pertussis_Homo sapiens_hsa051330.54824348
67Fatty acid biosynthesis_Homo sapiens_hsa000610.52203355
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.45694608
69* Metabolic pathways_Homo sapiens_hsa011000.45413294
70Prion diseases_Homo sapiens_hsa050200.36503479
71Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35405850
72Galactose metabolism_Homo sapiens_hsa000520.24845696
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24238755
74Insulin resistance_Homo sapiens_hsa049310.22646712
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.21665670
76Fructose and mannose metabolism_Homo sapiens_hsa000510.21348611
77Linoleic acid metabolism_Homo sapiens_hsa005910.20938027
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.18154156
79Glycerophospholipid metabolism_Homo sapiens_hsa005640.15389851
80Glucagon signaling pathway_Homo sapiens_hsa049220.09441067
81AMPK signaling pathway_Homo sapiens_hsa041520.01097425
82Ether lipid metabolism_Homo sapiens_hsa00565-0.2485648
83Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2434777
84Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2359752
85Amoebiasis_Homo sapiens_hsa05146-0.2358883
86Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2310141
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2070036
88Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.2038277
89Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1992370
90Renin-angiotensin system_Homo sapiens_hsa04614-0.1980351
91Hepatitis C_Homo sapiens_hsa05160-0.1788142
92Protein digestion and absorption_Homo sapiens_hsa04974-0.1739380
93Influenza A_Homo sapiens_hsa05164-0.1708719
94Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1681824
95Vascular smooth muscle contraction_Homo sapiens_hsa04270-0.1633615
96Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1612303
97Serotonergic synapse_Homo sapiens_hsa04726-0.1571514
98Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1546298
99NF-kappa B signaling pathway_Homo sapiens_hsa04064-0.1530574
100Mineral absorption_Homo sapiens_hsa04978-0.1509315
101African trypanosomiasis_Homo sapiens_hsa05143-0.1411278
102Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1381814
103Regulation of autophagy_Homo sapiens_hsa04140-0.1372792
104Acute myeloid leukemia_Homo sapiens_hsa05221-0.1111456
105Insulin signaling pathway_Homo sapiens_hsa04910-0.1052667
106Platelet activation_Homo sapiens_hsa04611-0.0999987
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0918333
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0886829
109Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0711087
110Sphingolipid metabolism_Homo sapiens_hsa00600-0.0604445
111Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532-0.0550265
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0476669
113Pancreatic secretion_Homo sapiens_hsa04972-0.0436540
114Lysosome_Homo sapiens_hsa04142-0.0380332

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