AMZ1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation by symbiont of host defense response (GO:0052509)5.60688804
2modulation by symbiont of host defense response (GO:0052031)5.60688804
3modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.60688804
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.60688804
5positive regulation by organism of defense response of other organism involved in symbiotic interact5.60688804
6modulation by symbiont of host immune response (GO:0052553)5.60688804
7microglial cell activation (GO:0001774)4.87545299
8macrophage activation involved in immune response (GO:0002281)4.63631782
9regulation of B cell receptor signaling pathway (GO:0050855)4.42865357
10antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.31937803
11regulation of interferon-beta biosynthetic process (GO:0045357)4.22232164
12response to pheromone (GO:0019236)4.14207108
13regulation of hippo signaling (GO:0035330)4.12375657
14neutrophil activation involved in immune response (GO:0002283)4.10947582
15positive regulation of cellular amide metabolic process (GO:0034250)4.00860829
16glycosphingolipid catabolic process (GO:0046479)3.96400753
17prostate gland growth (GO:0060736)3.85019652
18cell morphogenesis involved in neuron differentiation (GO:0048667)3.72746425
19oligosaccharide catabolic process (GO:0009313)3.70318865
20detection of light stimulus involved in sensory perception (GO:0050962)3.69911585
21detection of light stimulus involved in visual perception (GO:0050908)3.69911585
22macrophage activation (GO:0042116)3.69668335
23respiratory burst (GO:0045730)3.67947173
24sphingoid metabolic process (GO:0046519)3.67035817
25response to host immune response (GO:0052572)3.66826001
26response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.66826001
27diol metabolic process (GO:0034311)3.64324700
28negative regulation of cell killing (GO:0031342)3.57649033
29negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.57649033
30myeloid cell activation involved in immune response (GO:0002275)3.57442980
31G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.55535410
32cellular response to ATP (GO:0071318)3.54776766
33positive regulation of antigen processing and presentation (GO:0002579)3.50438944
34activated T cell proliferation (GO:0050798)3.49486036
35glycolipid catabolic process (GO:0019377)3.47564826
36multicellular organism reproduction (GO:0032504)3.46819086
37phagosome maturation (GO:0090382)3.45984307
38ceramide catabolic process (GO:0046514)3.44275166
39regulation of establishment of cell polarity (GO:2000114)3.41813661
40neutrophil activation (GO:0042119)3.39877350
41tryptophan catabolic process (GO:0006569)3.36026204
42indole-containing compound catabolic process (GO:0042436)3.36026204
43indolalkylamine catabolic process (GO:0046218)3.36026204
44sphingosine metabolic process (GO:0006670)3.34735358
45limb bud formation (GO:0060174)3.33436610
46regulation of establishment or maintenance of cell polarity (GO:0032878)3.30599919
47granulocyte activation (GO:0036230)3.29535049
48response to peptidoglycan (GO:0032494)3.23797543
49cellular extravasation (GO:0045123)3.23545141
50superoxide anion generation (GO:0042554)3.23420341
51response to host (GO:0075136)3.21504298
52response to host defenses (GO:0052200)3.21504298
53response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.21504298
54positive regulation of heat generation (GO:0031652)3.20890083
55platelet dense granule organization (GO:0060155)3.14938840
56response to muramyl dipeptide (GO:0032495)3.14513207
57regulation of mast cell degranulation (GO:0043304)3.12908789
58regulation of dendritic cell antigen processing and presentation (GO:0002604)3.10850410
59ovulation from ovarian follicle (GO:0001542)3.10811603
60production of molecular mediator involved in inflammatory response (GO:0002532)3.09168788
61positive regulation of gamma-delta T cell activation (GO:0046645)3.08987303
62mast cell activation (GO:0045576)3.08742094
63behavioral response to nicotine (GO:0035095)3.06553989
64negative regulation of interleukin-17 production (GO:0032700)3.05099075
65immunoglobulin mediated immune response (GO:0016064)3.04758419
66G-protein coupled receptor internalization (GO:0002031)3.03562420
67positive regulation of mast cell degranulation (GO:0043306)3.02659217
68positive regulation of mast cell activation involved in immune response (GO:0033008)3.02659217
69G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.01771825
70regulation of mast cell activation (GO:0033003)3.01738118
71positive regulation of mast cell activation (GO:0033005)3.01239084
72regulation of antigen processing and presentation (GO:0002577)2.98875086
73regulation of mast cell activation involved in immune response (GO:0033006)2.98694473
74cellular ketone body metabolic process (GO:0046950)2.93947253
75L-amino acid import (GO:0043092)2.93709434
76positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.92874479
77I-kappaB phosphorylation (GO:0007252)2.92302797
78neutrophil mediated immunity (GO:0002446)2.91003943
79myeloid dendritic cell differentiation (GO:0043011)2.89880205
80positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.89288330
81kynurenine metabolic process (GO:0070189)2.89248353
82G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.88945638
83myeloid leukocyte activation (GO:0002274)2.86872032
84regulation of myeloid leukocyte mediated immunity (GO:0002886)2.86309857
85positive regulation of monocyte chemotaxis (GO:0090026)2.85394609
86regulation of leukocyte degranulation (GO:0043300)2.82943675
87positive regulation of interferon-alpha production (GO:0032727)2.82896257
88regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.82109633
89NAD biosynthetic process (GO:0009435)2.82023220
90long term synaptic depression (GO:0060292)2.80177319
91startle response (GO:0001964)2.79716706
92coenzyme catabolic process (GO:0009109)2.79611336
93ketone body metabolic process (GO:1902224)2.77678511
94myeloid dendritic cell activation (GO:0001773)2.77166610
95reflex (GO:0060004)2.77015910
96mature B cell differentiation (GO:0002335)2.73589428
97negative regulation of mast cell activation (GO:0033004)2.72791643
98regulation of respiratory system process (GO:0044065)2.72698934
99cardiac right ventricle morphogenesis (GO:0003215)2.72009071
100negative regulation of cytosolic calcium ion concentration (GO:0051481)2.71611683
101regulation of acrosome reaction (GO:0060046)2.70933647
102nitric oxide biosynthetic process (GO:0006809)2.70583704
103mast cell degranulation (GO:0043303)2.70365301
104mast cell activation involved in immune response (GO:0002279)2.70365301
105detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.70201064
106locomotory exploration behavior (GO:0035641)2.69809233
107neuron cell-cell adhesion (GO:0007158)2.69540535
108epithelial cell maturation (GO:0002070)2.69131245
109ionotropic glutamate receptor signaling pathway (GO:0035235)2.68436552
110regulation of heat generation (GO:0031650)2.65716560
111lysosome organization (GO:0007040)2.65683942
112lytic vacuole organization (GO:0080171)2.65683942
113cornea development in camera-type eye (GO:0061303)2.65446301
114pyrimidine-containing compound transmembrane transport (GO:0072531)2.64812240
115purinergic receptor signaling pathway (GO:0035587)2.64760666
116defense response to protozoan (GO:0042832)2.63642868
117regulation of interferon-alpha production (GO:0032647)2.63406262
118regulation of B cell differentiation (GO:0045577)2.62739026
119G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.61860836
120histone H3-K9 methylation (GO:0051567)2.61484817
121positive regulation of B cell differentiation (GO:0045579)2.60361353
122germinal center formation (GO:0002467)2.59351326
123positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.58721891
124amino acid import (GO:0043090)2.58205842
125indolalkylamine metabolic process (GO:0006586)2.58046869
126B cell receptor signaling pathway (GO:0050853)2.57381982
127adenosine receptor signaling pathway (GO:0001973)2.56634073
128sympathetic nervous system development (GO:0048485)2.56301223
129sphingolipid catabolic process (GO:0030149)2.54526485
130regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.52913739
131pseudouridine synthesis (GO:0001522)2.51784841
132negative regulation of synaptic transmission, GABAergic (GO:0032229)2.51622275
133positive regulation of prostaglandin secretion (GO:0032308)2.50922561
134actin filament polymerization (GO:0030041)2.50910627
135sperm motility (GO:0030317)2.49730841
136detection of molecule of bacterial origin (GO:0032490)2.48303411
137central nervous system neuron axonogenesis (GO:0021955)2.47899189
138leukocyte degranulation (GO:0043299)2.45324034
139tryptophan metabolic process (GO:0006568)2.44951750
140Golgi to endosome transport (GO:0006895)2.44446589
141purinergic nucleotide receptor signaling pathway (GO:0035590)2.43666752
142ganglioside metabolic process (GO:0001573)2.43467202
143regulation of platelet aggregation (GO:0090330)2.43380768
144transferrin transport (GO:0033572)2.42437934
145postsynaptic membrane organization (GO:0001941)2.41504328
146regulation of regulated secretory pathway (GO:1903305)2.41434338
147signal peptide processing (GO:0006465)2.41323085
148auditory receptor cell stereocilium organization (GO:0060088)2.41214362
149regulation of translation, ncRNA-mediated (GO:0045974)2.40851146
150negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.40851146
151negative regulation of translation, ncRNA-mediated (GO:0040033)2.40851146
152dendritic cell differentiation (GO:0097028)2.40778958
153fucose catabolic process (GO:0019317)2.40190809
154L-fucose metabolic process (GO:0042354)2.40190809
155L-fucose catabolic process (GO:0042355)2.40190809
156regulation of interleukin-12 biosynthetic process (GO:0045075)2.39945216
157negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.39087672
158positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.38380065
159regulation of ruffle assembly (GO:1900027)2.37842373
160monocyte chemotaxis (GO:0002548)2.36505934
161neuronal action potential (GO:0019228)2.36210264
162lipopolysaccharide-mediated signaling pathway (GO:0031663)2.35965786
163transmission of nerve impulse (GO:0019226)2.35664514
164DNA methylation involved in gamete generation (GO:0043046)2.35188684
165neutrophil chemotaxis (GO:0030593)2.34478186
166negative regulation of cAMP-mediated signaling (GO:0043951)2.34451375
167phagocytosis, engulfment (GO:0006911)2.33899515
168activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.32691872
169piRNA metabolic process (GO:0034587)2.31933805
170glutamate receptor signaling pathway (GO:0007215)2.30661106
171alanine transport (GO:0032328)2.30259934
172acrosome reaction (GO:0007340)2.27882864
173pigment cell differentiation (GO:0050931)2.27532797
174regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.27373309
175regulation of rhodopsin mediated signaling pathway (GO:0022400)2.27200642
176glycerophospholipid catabolic process (GO:0046475)2.26048563
177regulation of calcium ion-dependent exocytosis (GO:0017158)2.25608369
178phasic smooth muscle contraction (GO:0014821)2.25347475
179basic amino acid transport (GO:0015802)2.24727940
180fatty acid transmembrane transport (GO:1902001)2.23264858
181positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.21296132
182photoreceptor cell maintenance (GO:0045494)2.20294294
183spinal cord motor neuron differentiation (GO:0021522)2.20021771
184rhodopsin mediated signaling pathway (GO:0016056)2.19835350
185nucleotide transmembrane transport (GO:1901679)2.19668920
186amine catabolic process (GO:0009310)2.18427433
187cellular biogenic amine catabolic process (GO:0042402)2.18427433
188regulation of Rab GTPase activity (GO:0032313)2.18074265
189positive regulation of Rab GTPase activity (GO:0032851)2.18074265
190establishment of protein localization to Golgi (GO:0072600)2.17976966
191reproduction (GO:0000003)2.17575277
192carnitine transport (GO:0015879)2.17288931
193amino-acid betaine transport (GO:0015838)2.17288931
194positive regulation of meiosis (GO:0045836)2.17268742
195negative regulation of organelle assembly (GO:1902116)2.17243916
196regulation of female receptivity (GO:0045924)2.17165554
197indole-containing compound metabolic process (GO:0042430)2.16446829

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.17455461
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.30725417
3ESR1_20079471_ChIP-ChIP_T-47D_Human4.13072752
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.40264556
5* IRF8_27001747_Chip-Seq_BMDM_Mouse3.30827473
6SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.10400138
7Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.85403391
8VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.76003473
9GBX2_23144817_ChIP-Seq_PC3_Human2.65976165
10ZNF274_21170338_ChIP-Seq_K562_Hela2.64481337
11ESR1_21235772_ChIP-Seq_MCF-7_Human2.63370321
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.56577451
13EZH2_22144423_ChIP-Seq_EOC_Human2.45390027
14IKZF1_21737484_ChIP-ChIP_HCT116_Human2.43318168
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.36676309
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.30750801
17CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.19879756
18ARNT_22903824_ChIP-Seq_MCF-7_Human2.12956636
19ESR2_21235772_ChIP-Seq_MCF-7_Human2.10858783
20NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.08184291
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99663010
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89039582
23SMAD_19615063_ChIP-ChIP_OVARY_Human1.87962226
24ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.87709099
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.86077501
26SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.86026974
27DROSHA_22980978_ChIP-Seq_HELA_Human1.85714244
28VDR_24787735_ChIP-Seq_THP-1_Human1.84997805
29TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.81381015
30POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.81381015
31JARID2_20064375_ChIP-Seq_MESCs_Mouse1.80210926
32STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.79993294
33SPI1_23127762_ChIP-Seq_K562_Human1.71705138
34SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.71370625
35AR_21572438_ChIP-Seq_LNCaP_Human1.70199865
36IGF1R_20145208_ChIP-Seq_DFB_Human1.68441334
37VDR_22108803_ChIP-Seq_LS180_Human1.65520946
38RUNX_20019798_ChIP-Seq_JUKART_Human1.65220726
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.63721027
40PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.62423892
41CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62008151
42PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.59385378
43EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.58519206
44SCL_19346495_ChIP-Seq_HPC-7_Human1.58425340
45BCAT_22108803_ChIP-Seq_LS180_Human1.57903574
46AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56982211
47SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.53076852
48CBP_20019798_ChIP-Seq_JUKART_Human1.51409155
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51409155
50HOXB7_26014856_ChIP-Seq_BT474_Human1.51365235
51STAT3_23295773_ChIP-Seq_U87_Human1.50212287
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49504540
53SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.43026262
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.42731678
55MTF2_20144788_ChIP-Seq_MESCs_Mouse1.42583022
56EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.42061363
57SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.40412369
58SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.39604397
59THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.38656376
60POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37306823
61BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.35234013
62NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.34802918
63* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.33995574
64FUS_26573619_Chip-Seq_HEK293_Human1.33317349
65EZH2_18974828_ChIP-Seq_MESCs_Mouse1.31973795
66RNF2_18974828_ChIP-Seq_MESCs_Mouse1.31973795
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31487810
68LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.31255687
69JARID2_20075857_ChIP-Seq_MESCs_Mouse1.30807733
70REST_21632747_ChIP-Seq_MESCs_Mouse1.29803377
71RXR_22108803_ChIP-Seq_LS180_Human1.28933254
72IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28277978
73* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27957173
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25955941
75ESR1_15608294_ChIP-ChIP_MCF-7_Human1.23705972
76TDRD3_21172665_ChIP-Seq_MCF-7_Human1.23292776
77EWS_26573619_Chip-Seq_HEK293_Human1.22787514
78IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.22576322
79PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.20572814
80ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.19812620
81SUZ12_27294783_Chip-Seq_ESCs_Mouse1.19666367
82TCF4_22108803_ChIP-Seq_LS180_Human1.18917798
83* GATA3_21878914_ChIP-Seq_MCF-7_Human1.17270014
84SPI1_23547873_ChIP-Seq_NB4_Human1.16940604
85FLI1_27457419_Chip-Seq_LIVER_Mouse1.16076941
86NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14882584
87TP53_22573176_ChIP-Seq_HFKS_Human1.14492674
88TOP2B_26459242_ChIP-Seq_MCF-7_Human1.14063056
89NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.12711213
90ER_23166858_ChIP-Seq_MCF-7_Human1.12540812
91CTBP1_25329375_ChIP-Seq_LNCAP_Human1.12202179
92FLI1_21867929_ChIP-Seq_TH2_Mouse1.11441762
93P300_19829295_ChIP-Seq_ESCs_Human1.11359394
94SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11233950
95SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.10795980
96SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.10284052
97RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.10265705
98ERA_21632823_ChIP-Seq_H3396_Human1.10056551
99VDR_24763502_ChIP-Seq_THP-1_Human1.09591395
100SMAD4_21799915_ChIP-Seq_A2780_Human1.09494422
101RARB_27405468_Chip-Seq_BRAIN_Mouse1.09439098
102MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.09246620
103EZH2_27304074_Chip-Seq_ESCs_Mouse1.06843785
104SOX2_19829295_ChIP-Seq_ESCs_Human1.05764209
105NANOG_19829295_ChIP-Seq_ESCs_Human1.05764209
106* RNF2_27304074_Chip-Seq_ESCs_Mouse1.05585607
107FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05485927
108FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.05107139
109FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.04788603
110MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04644933
111SMAD4_21741376_ChIP-Seq_EPCs_Human1.04362434
112EED_16625203_ChIP-ChIP_MESCs_Mouse1.03403280
113EZH2_27294783_Chip-Seq_ESCs_Mouse1.02958424
114CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02732262
115BRD4_27068464_Chip-Seq_AML-cells_Mouse1.02518349
116TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01685873
117CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01286878
118NOTCH1_21737748_ChIP-Seq_TLL_Human1.00541594
119TP53_16413492_ChIP-PET_HCT116_Human1.00529212
120PU_27001747_Chip-Seq_BMDM_Mouse1.00528242
121* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00527530
122ZNF217_24962896_ChIP-Seq_MCF-7_Human0.99879696
123STAT4_19710469_ChIP-ChIP_TH1__Mouse0.99811536
124* PRDM14_20953172_ChIP-Seq_ESCs_Human0.99747605
125TP53_18474530_ChIP-ChIP_U2OS_Human0.99651558
126CJUN_26792858_Chip-Seq_BT549_Human0.99564722
127CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99373278
128TAF15_26573619_Chip-Seq_HEK293_Human0.97861476
129UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97548081
130RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96931750
131AHR_22903824_ChIP-Seq_MCF-7_Human0.95166139
132TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94912233
133LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.94677122
134E2F1_18555785_Chip-Seq_ESCs_Mouse0.93935564
135RUNX1_27514584_Chip-Seq_MCF-7_Human0.93043738
136AR_25329375_ChIP-Seq_VCAP_Human0.92896695
137ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92511824
138GATA1_22025678_ChIP-Seq_K562_Human0.92296636
139MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90859427
140PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90858850
141NANOG_18555785_Chip-Seq_ESCs_Mouse0.90820276
142SMAD3_21741376_ChIP-Seq_EPCs_Human0.90795579
143GATA2_21666600_ChIP-Seq_HMVEC_Human0.90394668
144SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89798315
145* FOXA1_25329375_ChIP-Seq_VCAP_Human0.89552352
146* FOXA1_27270436_Chip-Seq_PROSTATE_Human0.89552352
147CTBP2_25329375_ChIP-Seq_LNCAP_Human0.88884325
148P53_22387025_ChIP-Seq_ESCs_Mouse0.88483942
149SALL1_21062744_ChIP-ChIP_HESCs_Human0.87598224
150GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87550422
151RUNX1_22412390_ChIP-Seq_EML_Mouse0.87382435
152CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.87324283
153NCOR_22424771_ChIP-Seq_293T_Human0.87216437
154KLF5_20875108_ChIP-Seq_MESCs_Mouse0.87026745
155* KDM2B_26808549_Chip-Seq_REH_Human0.86533470
156SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86375390
157OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85769920
158HIF1A_21447827_ChIP-Seq_MCF-7_Human0.85542445
159CMYC_18555785_Chip-Seq_ESCs_Mouse0.85313649
160EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.85238739
161SUZ12_18555785_Chip-Seq_ESCs_Mouse0.85135051
162* TCF4_23295773_ChIP-Seq_U87_Human0.84640875
163RUNX2_22187159_ChIP-Seq_PCA_Human0.83585134

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat6.15359820
2MP0001835_abnormal_antigen_presentation3.89885578
3MP0003172_abnormal_lysosome_physiology3.61204310
4MP0000427_abnormal_hair_cycle3.42550550
5MP0004510_myositis3.41643059
6MP0003136_yellow_coat_color3.39628067
7MP0003880_abnormal_central_pattern3.01860684
8MP0000569_abnormal_digit_pigmentation3.00294483
9MP0006082_CNS_inflammation2.71410075
10MP0003303_peritoneal_inflammation2.69639080
11MP0002419_abnormal_innate_immunity2.67243636
12MP0002148_abnormal_hypersensitivity_rea2.59430280
13MP0004859_abnormal_synaptic_plasticity2.55952955
14MP0003436_decreased_susceptibility_to2.49416063
15MP0003195_calcinosis2.48622338
16MP0001790_abnormal_immune_system2.45422077
17MP0005387_immune_system_phenotype2.45422077
18MP0005000_abnormal_immune_tolerance2.42199736
19MP0005058_abnormal_lysosome_morphology2.29790606
20MP0005174_abnormal_tail_pigmentation2.27135087
21MP0005248_abnormal_Harderian_gland2.25155169
22MP0005551_abnormal_eye_electrophysiolog2.23109618
23MP0002452_abnormal_antigen_presenting2.21145457
24MP0005671_abnormal_response_to2.15103528
25MP0009780_abnormal_chondrocyte_physiolo2.14774284
26MP0001800_abnormal_humoral_immune2.07374200
27MP0000372_irregular_coat_pigmentation2.07237868
28MP0005379_endocrine/exocrine_gland_phen2.04296224
29MP0002723_abnormal_immune_serum1.99574153
30MP0005310_abnormal_salivary_gland1.98663850
31MP0005257_abnormal_intraocular_pressure1.98199397
32MP0001919_abnormal_reproductive_system1.96959615
33MP0005646_abnormal_pituitary_gland1.95161372
34MP0005025_abnormal_response_to1.94803646
35MP0005464_abnormal_platelet_physiology1.93946542
36MP0003690_abnormal_glial_cell1.89084171
37MP0004381_abnormal_hair_follicle1.86175876
38MP0005410_abnormal_fertilization1.84201834
39MP0004742_abnormal_vestibular_system1.82965621
40MP0001819_abnormal_immune_cell1.81008254
41MP0000685_abnormal_immune_system1.79933702
42MP0000538_abnormal_urinary_bladder1.78781651
43MP0002420_abnormal_adaptive_immunity1.78655403
44MP0000015_abnormal_ear_pigmentation1.78116192
45MP0000383_abnormal_hair_follicle1.76723342
46MP0009745_abnormal_behavioral_response1.76335617
47MP0000371_diluted_coat_color1.71632162
48MP0002064_seizures1.68252379
49MP0000604_amyloidosis1.67657021
50MP0003183_abnormal_peptide_metabolism1.66340552
51MP0002736_abnormal_nociception_after1.62360587
52MP0001968_abnormal_touch/_nociception1.60613826
53MP0009785_altered_susceptibility_to1.59940959
54MP0002909_abnormal_adrenal_gland1.59904938
55MP0006072_abnormal_retinal_apoptosis1.59606737
56MP0003635_abnormal_synaptic_transmissio1.58551592
57MP0010678_abnormal_skin_adnexa1.56246167
58MP0005075_abnormal_melanosome_morpholog1.54752076
59MP0003724_increased_susceptibility_to1.54144256
60MP0006276_abnormal_autonomic_nervous1.53100382
61MP0003075_altered_response_to1.52522436
62MP0009046_muscle_twitch1.50593013
63MP0002405_respiratory_system_inflammati1.47724013
64MP0001501_abnormal_sleep_pattern1.47689778
65MP0008872_abnormal_physiological_respon1.40920560
66MP0001853_heart_inflammation1.40748176
67MP0001486_abnormal_startle_reflex1.39213848
68MP0005409_darkened_coat_color1.36988471
69MP0002837_dystrophic_cardiac_calcinosis1.36868491
70MP0002090_abnormal_vision1.36057443
71MP0002735_abnormal_chemical_nociception1.35636352
72MP0005645_abnormal_hypothalamus_physiol1.35062131
73MP0002572_abnormal_emotion/affect_behav1.33106205
74MP0000920_abnormal_myelination1.32961812
75MP0005253_abnormal_eye_physiology1.31512947
76MP0005423_abnormal_somatic_nervous1.29279375
77MP0002063_abnormal_learning/memory/cond1.28661664
78MP0002998_abnormal_bone_remodeling1.28258924
79MP0005389_reproductive_system_phenotype1.26198559
80MP0001533_abnormal_skeleton_physiology1.25026176
81MP0004264_abnormal_extraembryonic_tissu1.22607948
82MP0002102_abnormal_ear_morphology1.22018474
83MP0002693_abnormal_pancreas_physiology1.21518675
84MP0001851_eye_inflammation1.20839042
85MP0001881_abnormal_mammary_gland1.20281452
86MP0000716_abnormal_immune_system1.18577011
87MP0001664_abnormal_digestion1.17446884
88MP0000343_altered_response_to1.14360223
89MP0001440_abnormal_grooming_behavior1.11825894
90MP0010386_abnormal_urinary_bladder1.11786252
91MP0001845_abnormal_inflammatory_respons1.11179670
92MP0000681_abnormal_thyroid_gland1.09949816
93MP0003191_abnormal_cellular_cholesterol1.09844043
94MP0005166_decreased_susceptibility_to1.09053475
95MP0008877_abnormal_DNA_methylation1.09048657
96MP0003936_abnormal_reproductive_system1.08443545
97MP0003448_altered_tumor_morphology1.06719250
98MP0002229_neurodegeneration1.06119413
99MP0003329_amyloid_beta_deposits1.05420314
100MP0002098_abnormal_vibrissa_morphology1.04179716
101MP0002067_abnormal_sensory_capabilities1.03003245
102MP0002398_abnormal_bone_marrow1.02745818
103MP0003300_gastrointestinal_ulcer1.01958648
104MP0002272_abnormal_nervous_system1.01534629
105MP0001756_abnormal_urination1.00932846
106MP0001986_abnormal_taste_sensitivity0.99139417
107MP0001873_stomach_inflammation0.98615103
108MP0000689_abnormal_spleen_morphology0.97432850
109MP0003828_pulmonary_edema0.96688623
110MP0004043_abnormal_pH_regulation0.96138588
111MP0005167_abnormal_blood-brain_barrier0.95619927
112MP0005408_hypopigmentation0.94150712
113MP0002168_other_aberrant_phenotype0.93704243
114MP0005084_abnormal_gallbladder_morpholo0.93003800
115MP0000465_gastrointestinal_hemorrhage0.92385828
116MP0008260_abnormal_autophagy0.92037279
117MP0008469_abnormal_protein_level0.92021884
118MP0002751_abnormal_autonomic_nervous0.91063082
119MP0003787_abnormal_imprinting0.88805572
120MP0004885_abnormal_endolymph0.87397942
121MP0001970_abnormal_pain_threshold0.86297444
122MP0002095_abnormal_skin_pigmentation0.85702148
123MP0009764_decreased_sensitivity_to0.84301164
124MP0000627_abnormal_mammary_gland0.83048565
125MP0010155_abnormal_intestine_physiology0.82425428
126MP0009333_abnormal_splenocyte_physiolog0.82405884
127MP0002734_abnormal_mechanical_nocicepti0.82195802
128MP0009278_abnormal_bone_marrow0.81619460
129MP0002653_abnormal_ependyma_morphology0.81544329
130MP0002722_abnormal_immune_system0.80305592
131MP0002138_abnormal_hepatobiliary_system0.80284536
132MP0002429_abnormal_blood_cell0.80071194
133MP0002075_abnormal_coat/hair_pigmentati0.79699278
134MP0001188_hyperpigmentation0.79483768
135MP0002557_abnormal_social/conspecific_i0.78592572
136MP0002876_abnormal_thyroid_physiology0.78397757
137MP0003634_abnormal_glial_cell0.78207656
138MP0002733_abnormal_thermal_nociception0.77661594
139MP0000470_abnormal_stomach_morphology0.77055447
140MP0001944_abnormal_pancreas_morphology0.76343348
141MP0003698_abnormal_male_reproductive0.74178170
142MP0004924_abnormal_behavior0.73950396
143MP0005386_behavior/neurological_phenoty0.73950396
144MP0003633_abnormal_nervous_system0.73938822
145MP0002184_abnormal_innervation0.73926602
146MP0005367_renal/urinary_system_phenotyp0.72434552
147MP0000516_abnormal_urinary_system0.72434552
148MP0002933_joint_inflammation0.71730590
149MP0005171_absent_coat_pigmentation0.71455929
150MP0003866_abnormal_defecation0.71083345
151MP0004147_increased_porphyrin_level0.71001155
152MP0009384_cardiac_valve_regurgitation0.70881209
153MP0001529_abnormal_vocalization0.69844938
154MP0004883_abnormal_blood_vessel0.69565593
155MP0003879_abnormal_hair_cell0.69426815
156MP0002277_abnormal_respiratory_mucosa0.69184193
157MP0003950_abnormal_plasma_membrane0.67213842
158MP0002160_abnormal_reproductive_system0.66604826
159MP0004233_abnormal_muscle_weight0.65688421
160MP0003045_fibrosis0.64466458
161MP0004019_abnormal_vitamin_homeostasis0.64175819
162MP0001663_abnormal_digestive_system0.64097052
163MP0003806_abnormal_nucleotide_metabolis0.63556595
164MP0001502_abnormal_circadian_rhythm0.63334112
165MP0000647_abnormal_sebaceous_gland0.63070800
166MP0004133_heterotaxia0.62945682
167MP0005195_abnormal_posterior_eye0.62366606
168MP0000026_abnormal_inner_ear0.61060422

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.31277052
2Recurrent bacterial skin infections (HP:0005406)5.76413940
3Eczematoid dermatitis (HP:0000976)5.48313386
4Hyperventilation (HP:0002883)5.38504595
5Congenital stationary night blindness (HP:0007642)5.19542801
6Increased cerebral lipofuscin (HP:0011813)4.87375650
7Abnormality of liposaccharide metabolism (HP:0010968)4.71887802
8Abnormality of glycosphingolipid metabolism (HP:0004343)4.71887802
9Abnormality of glycolipid metabolism (HP:0010969)4.71887802
10Recurrent gram-negative bacterial infections (HP:0005420)4.47217434
11Increased neuronal autofluorescent lipopigment (HP:0002074)4.43372235
12Concave nail (HP:0001598)4.43092248
13Abnormality of macrophages (HP:0004311)4.20657288
14Obstructive lung disease (HP:0006536)4.00492586
15Chronic obstructive pulmonary disease (HP:0006510)4.00492586
16Vacuolated lymphocytes (HP:0001922)3.80845913
17Recurrent skin infections (HP:0001581)3.78501025
18Mediastinal lymphadenopathy (HP:0100721)3.58395725
19Axonal loss (HP:0003447)3.56336495
20Chronic mucocutaneous candidiasis (HP:0002728)3.49065759
21Recurrent cutaneous fungal infections (HP:0011370)3.49065759
22Pancreatic cysts (HP:0001737)3.48074002
23Recurrent fungal infections (HP:0002841)3.42644635
24Disinhibition (HP:0000734)3.37782994
25Agnosia (HP:0010524)3.35046950
26Gingivitis (HP:0000230)3.30270762
27Attenuation of retinal blood vessels (HP:0007843)3.22198736
28Severe visual impairment (HP:0001141)3.21124661
29Systemic lupus erythematosus (HP:0002725)3.20786507
30Abnormality of macular pigmentation (HP:0008002)3.10286965
31Protruding tongue (HP:0010808)3.06191126
32Focal motor seizures (HP:0011153)3.04303575
33Clumsiness (HP:0002312)3.01565248
34Dysostosis multiplex (HP:0000943)3.00808643
35Stomatitis (HP:0010280)2.95950787
36True hermaphroditism (HP:0010459)2.94618603
37Optic neuritis (HP:0100653)2.90574330
38Retrobulbar optic neuritis (HP:0100654)2.90574330
39Amelogenesis imperfecta (HP:0000705)2.89521856
40Albinism (HP:0001022)2.87208153
41Prostate neoplasm (HP:0100787)2.85318497
42Molar tooth sign on MRI (HP:0002419)2.80886275
43Abnormality of midbrain morphology (HP:0002418)2.80886275
44Nephronophthisis (HP:0000090)2.80686300
45Absent speech (HP:0001344)2.79830966
46Type II lissencephaly (HP:0007260)2.77096143
47Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.76332265
48Absent frontal sinuses (HP:0002688)2.75992695
49Pancreatic fibrosis (HP:0100732)2.75652796
50Glomerulonephritis (HP:0000099)2.74262489
51Myositis (HP:0100614)2.69289043
52Abnormality of mucopolysaccharide metabolism (HP:0011020)2.65333319
53Abnormality of polysaccharide metabolism (HP:0011012)2.65333319
54Abnormality of glycosaminoglycan metabolism (HP:0004371)2.65333319
55Abnormality of the renal medulla (HP:0100957)2.64503985
56Mutism (HP:0002300)2.58556493
57J-shaped sella turcica (HP:0002680)2.58344306
58Congenital sensorineural hearing impairment (HP:0008527)2.56532212
59Inappropriate behavior (HP:0000719)2.55151904
60Diplopia (HP:0000651)2.54644836
61Abnormality of binocular vision (HP:0011514)2.54644836
62Abnormal ciliary motility (HP:0012262)2.53458351
63Orchitis (HP:0100796)2.51527344
64Meningitis (HP:0001287)2.50551846
65Mucopolysacchariduria (HP:0008155)2.50104441
66Urinary glycosaminoglycan excretion (HP:0003541)2.50104441
67Elevated erythrocyte sedimentation rate (HP:0003565)2.47884963
68Medial flaring of the eyebrow (HP:0010747)2.47448575
69Widely spaced teeth (HP:0000687)2.44812625
70Bony spicule pigmentary retinopathy (HP:0007737)2.42073873
71Decreased electroretinogram (ERG) amplitude (HP:0000654)2.41211623
72Neonatal respiratory distress (HP:0002643)2.40964879
73Progressive cerebellar ataxia (HP:0002073)2.39423896
74Supranuclear gaze palsy (HP:0000605)2.38859163
75Hemiparesis (HP:0001269)2.38176411
76Tubular atrophy (HP:0000092)2.37494046
77Polydipsia (HP:0001959)2.33809756
78Abnormal drinking behavior (HP:0030082)2.33809756
79Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.28605698
80Neuronal loss in central nervous system (HP:0002529)2.27285801
81Apathy (HP:0000741)2.26791908
82Vasculitis (HP:0002633)2.26448538
83Prolonged bleeding time (HP:0003010)2.26150360
84IgM deficiency (HP:0002850)2.24309902
85Abnormality of the renal cortex (HP:0011035)2.23335047
86Recurrent viral infections (HP:0004429)2.23160016
87Recurrent pneumonia (HP:0006532)2.22547282
88Ketosis (HP:0001946)2.21984877
89Abnormal rod and cone electroretinograms (HP:0008323)2.20466087
90Focal seizures (HP:0007359)2.20260228
91Neurofibrillary tangles (HP:0002185)2.19980339
92Large for gestational age (HP:0001520)2.19016642
93Breast carcinoma (HP:0003002)2.18569481
94Loss of speech (HP:0002371)2.18058798
95Colitis (HP:0002583)2.17167090
96Metaphyseal dysplasia (HP:0100255)2.15585029
97Aplasia/Hypoplasia of the tongue (HP:0010295)2.14295154
98Diminished motivation (HP:0000745)2.14218323
99Cellulitis (HP:0100658)2.13675317
100Gait imbalance (HP:0002141)2.12268188
101Cystic liver disease (HP:0006706)2.09738518
102Inability to walk (HP:0002540)2.08661607
103Cheilitis (HP:0100825)2.08104659
104Febrile seizures (HP:0002373)2.07957405
105Gaze-evoked nystagmus (HP:0000640)2.06180276
106Chronic otitis media (HP:0000389)2.05154879
107Abolished electroretinogram (ERG) (HP:0000550)2.05128826
108Abnormality of dental color (HP:0011073)2.04807500
109Inflammation of the large intestine (HP:0002037)2.04527117
110Abnormal delayed hypersensitivity skin test (HP:0002963)2.01317259
111Cerebellar dysplasia (HP:0007033)2.00090965
112Osteomyelitis (HP:0002754)1.99706519
113Pulmonary infiltrates (HP:0002113)1.99489064
114Visual hallucinations (HP:0002367)1.97887281
115Chromosomal breakage induced by crosslinking agents (HP:0003221)1.97316636
116Mesangial abnormality (HP:0001966)1.96257808
117Congenital primary aphakia (HP:0007707)1.95961818
118Ketoacidosis (HP:0001993)1.95774354
119Generalized hypopigmentation (HP:0007513)1.94072401
120Thoracic kyphosis (HP:0002942)1.93635623
121Short 1st metacarpal (HP:0010034)1.91685701
122Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.91685701
123Polyuria (HP:0000103)1.90792037
124Congenital hepatic fibrosis (HP:0002612)1.90402461
125Spontaneous hematomas (HP:0007420)1.90244081
126Type I diabetes mellitus (HP:0100651)1.89384526
127Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.89086286
128Hepatosplenomegaly (HP:0001433)1.89008701
129Hemoptysis (HP:0002105)1.87963773
130Abnormality of the pons (HP:0007361)1.85219059
131Urticaria (HP:0001025)1.84913473
132Pendular nystagmus (HP:0012043)1.84717083
133Pachygyria (HP:0001302)1.84229768
134Hypoplasia of the pons (HP:0012110)1.83937442
135Basal ganglia calcification (HP:0002135)1.83331143
136Upper limb muscle weakness (HP:0003484)1.82878845
137Recurrent lower respiratory tract infections (HP:0002783)1.81884544
138Myocardial infarction (HP:0001658)1.81697290
139Genetic anticipation (HP:0003743)1.81145932
140Abnormality of the frontal sinuses (HP:0002687)1.80997074
141Stomach cancer (HP:0012126)1.80252548
142Tetany (HP:0001281)1.79909211
143Epiphyseal dysplasia (HP:0002656)1.79796082
144Intellectual disability, progressive (HP:0006887)1.79772079
145Poor head control (HP:0002421)1.78575127
146Gastrointestinal inflammation (HP:0004386)1.77881392
147Deformed sella turcica (HP:0002681)1.77059537
148Spondylolisthesis (HP:0003302)1.76451711
149Peripheral demyelination (HP:0011096)1.75524016
150Submucous cleft hard palate (HP:0000176)1.74979707
151Ocular albinism (HP:0001107)1.74762902
152Furrowed tongue (HP:0000221)1.73920832
153Leukocytosis (HP:0001974)1.73402691
154Macroglossia (HP:0000158)1.72213547
155Lower limb amyotrophy (HP:0007210)1.71928294
156Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.71877105
157Bile duct proliferation (HP:0001408)1.71455450
158Abnormal biliary tract physiology (HP:0012439)1.71455450
159Joint hemorrhage (HP:0005261)1.71313033
160Thick nail (HP:0001805)1.70832606
161Tongue fasciculations (HP:0001308)1.70674991
162Obstructive sleep apnea (HP:0002870)1.69927257
163Progressive inability to walk (HP:0002505)1.69830830
164Abnormality of the sella turcica (HP:0002679)1.69708827
165Genital tract atresia (HP:0001827)1.69339812
166Parakeratosis (HP:0001036)1.69095519
167Periodontitis (HP:0000704)1.68621785
168Disproportionate short-trunk short stature (HP:0003521)1.68403295
169Agammaglobulinemia (HP:0004432)1.68189963
170Dialeptic seizures (HP:0011146)1.67783446
171Cerebral inclusion bodies (HP:0100314)1.67487316
172Dementia (HP:0000726)1.67398506
173Distal lower limb amyotrophy (HP:0008944)1.67386436
174Lissencephaly (HP:0001339)1.66971697
175Broad-based gait (HP:0002136)1.66368888
176EEG with generalized epileptiform discharges (HP:0011198)1.65560152
177Generalized hypopigmentation of hair (HP:0011358)1.65500932
178Decreased central vision (HP:0007663)1.64710618
179Nephrogenic diabetes insipidus (HP:0009806)1.63567354
180Meningioma (HP:0002858)1.62478794
181Abnormality of the femoral head (HP:0003368)1.61782482
182Infertility (HP:0000789)1.61681183

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK6.22342381
2RIPK44.73494507
3TESK24.02170411
4IRAK43.55702502
5FES3.42576835
6MAP4K13.38935448
7MUSK3.32147788
8PINK13.15922244
9MAPKAPK33.01741806
10MAP4K23.01193875
11CASK2.78555994
12SIK22.74494884
13EPHA42.63103921
14MAP3K142.50635343
15IRAK32.32393470
16BLK2.30395692
17ACVR1B2.19487675
18SIK32.16843124
19MAP3K132.02048447
20INSRR1.95794218
21KIT1.84938593
22TGFBR21.82138621
23TBK11.81585981
24GRK71.78586106
25NTRK31.78339508
26FGR1.76155370
27WNK31.68324817
28MAPK131.63237833
29ZAK1.59838017
30STK38L1.59559815
31CSF1R1.58126121
32LATS11.50883440
33BMPR21.49079137
34JAK31.48940631
35SYK1.46687263
36TRIM281.44243753
37HCK1.40360126
38TXK1.39196350
39IKBKB1.39184452
40TNIK1.38064607
41IKBKE1.37905188
42TYK21.25724876
43CAMK1G1.22367254
44BMPR1B1.21959685
45IRAK21.20183004
46ADRBK21.18445693
47RPS6KB21.16792848
48CSK1.16650579
49YES11.15361815
50LYN1.14135126
51TEC1.13348051
52EIF2AK31.12955105
53CLK11.11692391
54PIK3CA1.10678313
55EPHB11.09900620
56AKT31.09387352
57CAMK1D1.08834489
58DAPK21.03626022
59STK381.03050103
60LCK1.00377322
61MAP2K70.99820963
62FER0.96786855
63PRKD20.95700008
64NTRK20.95688653
65JAK10.95412355
66NUAK10.94078790
67TLK10.93746182
68BTK0.92937196
69MARK30.90268276
70MAP2K20.89826990
71ADRBK10.83146489
72MAP2K10.83093813
73PLK20.82680011
74PNCK0.82598985
75PKN20.81992235
76CAMKK10.80298700
77PRKCQ0.79869115
78IRAK10.79838731
79MAP3K90.78374581
80MAP3K40.77921744
81MAPK150.77768734
82MAP2K60.76421978
83NEK60.76237519
84GRK10.73156444
85MAP3K120.71917209
86TNK20.71330548
87PDK10.71124334
88EPHA30.69014420
89ZAP700.68651788
90PKN10.68321869
91ABL20.68309552
92DMPK0.68148558
93MYLK0.67194658
94CAMK2D0.65471896
95PTK2B0.64945617
96PRKCI0.64357944
97ITK0.64200628
98SGK20.63856559
99PDPK10.63833331
100JAK20.63542982
101PRKCZ0.63094877
102CAMK2B0.62647708
103PHKG10.62012346
104PHKG20.62012346
105PRKD30.61634030
106GRK50.60104880
107NTRK10.59789344
108FYN0.59542579
109TAOK10.59092729
110PRPF4B0.58905726
111CAMK2G0.58266502
112RPS6KA20.57439212
113TAOK30.57091870
114DAPK10.56627692
115CAMKK20.55763757
116ABL10.55303581
117PRKCD0.52723301
118CDK50.52247144
119PRKAA20.52236238
120SGK4940.52155844
121SGK2230.52155844
122CSNK1A10.52130716
123PAK30.51439498
124CAMK2A0.51327024
125PDGFRB0.51110273
126TAOK20.50875639
127STK30.49639370
128GRK60.49291906
129MAPK70.48680093
130CHUK0.48426410
131CSNK1A1L0.48138757
132SGK10.47557015
133MINK10.46920449
134MAPK120.46255398
135TAF10.45965819
136PRKCG0.45877173
137EGFR0.45533550
138CSNK1D0.44821176
139EIF2AK20.44626035
140MOS0.44023666
141STK110.40917107
142DYRK1A0.39628847
143LIMK10.39627035
144MST40.39531271
145INSR0.38714014
146NME10.38062001
147CAMK10.37919880
148WNK40.37852973
149PRKCE0.37113688
150PRKD10.35733979
151MARK10.35307872
152MAP3K10.35228060
153MAPK80.34842906
154MATK0.34594530
155ERBB20.34130562
156NEK90.33862382
157KSR10.33784596
158CSNK1G30.32114543
159TGFBR10.31678935
160RIPK10.31508320
161SRC0.31266472
162TESK10.31154590
163RPS6KA60.28917185
164RPS6KB10.27784445
165DYRK20.26415293
166CSNK1G20.26315820

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.68864805
2Other glycan degradation_Homo sapiens_hsa005112.53114741
3Collecting duct acid secretion_Homo sapiens_hsa049662.38792636
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.24733473
5Osteoclast differentiation_Homo sapiens_hsa043802.22796631
6Leishmaniasis_Homo sapiens_hsa051402.19751084
7Glycosaminoglycan degradation_Homo sapiens_hsa005312.12797218
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.10453887
9Rheumatoid arthritis_Homo sapiens_hsa053232.08789371
10Lysosome_Homo sapiens_hsa041422.01152327
11Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.97605203
12B cell receptor signaling pathway_Homo sapiens_hsa046621.93511046
13ABC transporters_Homo sapiens_hsa020101.91525452
14Nicotine addiction_Homo sapiens_hsa050331.84802273
15Tuberculosis_Homo sapiens_hsa051521.83402314
16Phagosome_Homo sapiens_hsa041451.77036375
17Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.74208999
18Butanoate metabolism_Homo sapiens_hsa006501.74040008
19Synaptic vesicle cycle_Homo sapiens_hsa047211.72780271
20Toll-like receptor signaling pathway_Homo sapiens_hsa046201.66955911
21Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.64817373
22Morphine addiction_Homo sapiens_hsa050321.63442995
23Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.60089439
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.57340964
25Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.56855680
26Staphylococcus aureus infection_Homo sapiens_hsa051501.53694606
27NF-kappa B signaling pathway_Homo sapiens_hsa040641.51433321
28Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.49935223
29alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.49925972
30Nitrogen metabolism_Homo sapiens_hsa009101.47919502
31Chemokine signaling pathway_Homo sapiens_hsa040621.42063892
32Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.39809772
33Ether lipid metabolism_Homo sapiens_hsa005651.39807790
34Circadian rhythm_Homo sapiens_hsa047101.34352526
35Olfactory transduction_Homo sapiens_hsa047401.33692467
36Pertussis_Homo sapiens_hsa051331.33273721
37Glutamatergic synapse_Homo sapiens_hsa047241.30207482
38Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.26568115
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.26233417
40Graft-versus-host disease_Homo sapiens_hsa053321.23875639
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22016090
42Intestinal immune network for IgA production_Homo sapiens_hsa046721.20872405
43Salmonella infection_Homo sapiens_hsa051321.17028211
44Insulin secretion_Homo sapiens_hsa049111.16976809
45NOD-like receptor signaling pathway_Homo sapiens_hsa046211.16552819
46Measles_Homo sapiens_hsa051621.15378739
47Circadian entrainment_Homo sapiens_hsa047131.12896376
48Serotonergic synapse_Homo sapiens_hsa047261.11115515
49T cell receptor signaling pathway_Homo sapiens_hsa046601.10220600
50Linoleic acid metabolism_Homo sapiens_hsa005911.09631003
51Malaria_Homo sapiens_hsa051441.09154310
52Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.07668420
53Salivary secretion_Homo sapiens_hsa049701.07001801
54GABAergic synapse_Homo sapiens_hsa047271.06955349
55Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.06813921
56Hematopoietic cell lineage_Homo sapiens_hsa046401.06695701
57Cholinergic synapse_Homo sapiens_hsa047251.06457637
58Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.06356927
59Fanconi anemia pathway_Homo sapiens_hsa034601.05111207
60Shigellosis_Homo sapiens_hsa051311.01891514
61Asthma_Homo sapiens_hsa053101.01122012
62Vibrio cholerae infection_Homo sapiens_hsa051101.01049227
63Allograft rejection_Homo sapiens_hsa053300.97985866
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97409371
65Ovarian steroidogenesis_Homo sapiens_hsa049130.96653841
66African trypanosomiasis_Homo sapiens_hsa051430.96152321
67Renin secretion_Homo sapiens_hsa049240.95676037
68Steroid hormone biosynthesis_Homo sapiens_hsa001400.95597060
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.94876564
70Tryptophan metabolism_Homo sapiens_hsa003800.94714299
71Taste transduction_Homo sapiens_hsa047420.94521477
72RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.94484637
73Long-term potentiation_Homo sapiens_hsa047200.93086470
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.92891637
75Basal transcription factors_Homo sapiens_hsa030220.92608933
76Platelet activation_Homo sapiens_hsa046110.90341430
77Calcium signaling pathway_Homo sapiens_hsa040200.90194865
78Cocaine addiction_Homo sapiens_hsa050300.89677853
79TNF signaling pathway_Homo sapiens_hsa046680.87444739
80Long-term depression_Homo sapiens_hsa047300.87085328
81Propanoate metabolism_Homo sapiens_hsa006400.86983782
82Sphingolipid metabolism_Homo sapiens_hsa006000.86914425
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84517511
84Toxoplasmosis_Homo sapiens_hsa051450.84073021
85Sulfur relay system_Homo sapiens_hsa041220.83947206
86Influenza A_Homo sapiens_hsa051640.82973985
87GnRH signaling pathway_Homo sapiens_hsa049120.81728717
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.81046155
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.80539767
90Primary immunodeficiency_Homo sapiens_hsa053400.80528512
91Gastric acid secretion_Homo sapiens_hsa049710.79970991
92Vascular smooth muscle contraction_Homo sapiens_hsa042700.79403376
93RNA polymerase_Homo sapiens_hsa030200.79150625
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.78835686
95Mineral absorption_Homo sapiens_hsa049780.78098935
96Aldosterone synthesis and secretion_Homo sapiens_hsa049250.77553577
97Selenocompound metabolism_Homo sapiens_hsa004500.75968234
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.75900099
99Dopaminergic synapse_Homo sapiens_hsa047280.75367805
100Oxytocin signaling pathway_Homo sapiens_hsa049210.74853668
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74511176
102Apoptosis_Homo sapiens_hsa042100.72933381
103Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72543904
104Amphetamine addiction_Homo sapiens_hsa050310.72402326
105Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71488759
106Type II diabetes mellitus_Homo sapiens_hsa049300.71158391
107Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.70569544
108Dorso-ventral axis formation_Homo sapiens_hsa043200.69801389
109cAMP signaling pathway_Homo sapiens_hsa040240.68598958
110Sulfur metabolism_Homo sapiens_hsa009200.67619646
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.67228372
112Type I diabetes mellitus_Homo sapiens_hsa049400.66654899
113Antigen processing and presentation_Homo sapiens_hsa046120.66229189
114Melanoma_Homo sapiens_hsa052180.65875383
115Choline metabolism in cancer_Homo sapiens_hsa052310.64328664
116Pancreatic cancer_Homo sapiens_hsa052120.63435796
117Leukocyte transendothelial migration_Homo sapiens_hsa046700.63172688
118Jak-STAT signaling pathway_Homo sapiens_hsa046300.62829060
119Estrogen signaling pathway_Homo sapiens_hsa049150.62716001
120Glioma_Homo sapiens_hsa052140.62583810
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62574303
122Inositol phosphate metabolism_Homo sapiens_hsa005620.61435859
123Prolactin signaling pathway_Homo sapiens_hsa049170.61271138
124MAPK signaling pathway_Homo sapiens_hsa040100.61084031
125Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60973350
126Hepatitis B_Homo sapiens_hsa051610.60551241
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60112182
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.59553189
129Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.57761032
130Legionellosis_Homo sapiens_hsa051340.57674695
131Primary bile acid biosynthesis_Homo sapiens_hsa001200.57366382
132Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56669825
133Vitamin digestion and absorption_Homo sapiens_hsa049770.56060600
134Endocytosis_Homo sapiens_hsa041440.53353302
135ErbB signaling pathway_Homo sapiens_hsa040120.53002051
136Caffeine metabolism_Homo sapiens_hsa002320.52580350
137Chronic myeloid leukemia_Homo sapiens_hsa052200.52533961
138AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52381488
139Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.52140937
140Homologous recombination_Homo sapiens_hsa034400.49272744
141beta-Alanine metabolism_Homo sapiens_hsa004100.46951570
142Insulin resistance_Homo sapiens_hsa049310.43763959
143Autoimmune thyroid disease_Homo sapiens_hsa053200.39973551
144Chemical carcinogenesis_Homo sapiens_hsa052040.36794222
145Bladder cancer_Homo sapiens_hsa052190.34397923
146Glycerophospholipid metabolism_Homo sapiens_hsa005640.32841300

Most similar genes based on co-expression Upload to Enrichr

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