ANKIB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)6.78720682
2central nervous system myelination (GO:0022010)6.78720682
3myelination (GO:0042552)4.21690248
4axon ensheathment (GO:0008366)4.20442452
5ensheathment of neurons (GO:0007272)4.20442452
6negative regulation of neurotransmitter secretion (GO:0046929)4.16094865
7import into cell (GO:0098657)3.78966001
8fatty acid elongation (GO:0030497)3.76952231
9positive regulation of neurological system process (GO:0031646)3.73440586
10long-chain fatty acid biosynthetic process (GO:0042759)3.60339548
11negative regulation of neurotransmitter transport (GO:0051589)3.59086286
12UDP-N-acetylglucosamine metabolic process (GO:0006047)3.56126295
13presynaptic membrane assembly (GO:0097105)3.50076268
14myelin maintenance (GO:0043217)3.45497007
15negative regulation of DNA repair (GO:0045738)3.45101714
16nerve growth factor signaling pathway (GO:0038180)3.40192351
17presynaptic membrane organization (GO:0097090)3.35872085
18L-amino acid import (GO:0043092)3.34977554
19nuclear pore complex assembly (GO:0051292)3.29152222
20regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.27388132
21photoreceptor cell differentiation (GO:0046530)3.26834925
22eye photoreceptor cell differentiation (GO:0001754)3.26834925
23urate metabolic process (GO:0046415)3.20012374
24regulation of RNA export from nucleus (GO:0046831)3.18341387
25endocrine hormone secretion (GO:0060986)3.14566418
26regulation of Rac protein signal transduction (GO:0035020)3.11912364
27embryonic retina morphogenesis in camera-type eye (GO:0060059)3.07032652
28establishment of nucleus localization (GO:0040023)3.04723988
29response to lipoprotein particle (GO:0055094)3.03796858
30asymmetric protein localization (GO:0008105)3.02891230
31COPII vesicle coating (GO:0048208)3.02380207
32oligodendrocyte differentiation (GO:0048709)3.02066599
33axonal fasciculation (GO:0007413)2.93453459
34growth hormone receptor signaling pathway (GO:0060396)2.92422087
35cerebral cortex radially oriented cell migration (GO:0021799)2.90720119
36regulation of axon extension involved in axon guidance (GO:0048841)2.88944180
37phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.88621223
38limb bud formation (GO:0060174)2.85937269
39astrocyte development (GO:0014002)2.84817880
40suckling behavior (GO:0001967)2.84591705
41hippo signaling (GO:0035329)2.83358856
42regulation of nucleobase-containing compound transport (GO:0032239)2.82041077
43acrosome assembly (GO:0001675)2.74520942
44ear development (GO:0043583)2.73198373
45positive regulation of oligodendrocyte differentiation (GO:0048714)2.72600736
46insulin-like growth factor receptor signaling pathway (GO:0048009)2.72378544
47amino acid import (GO:0043090)2.70196518
48nucleotide-sugar biosynthetic process (GO:0009226)2.68592675
49regulation of NFAT protein import into nucleus (GO:0051532)2.68291462
50peptidyl-tyrosine autophosphorylation (GO:0038083)2.66747479
51Golgi to endosome transport (GO:0006895)2.62448783
52positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.60561087
53positive regulation of mitotic sister chromatid separation (GO:1901970)2.60561087
54positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.60561087
55negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.59919220
56spermatid nucleus differentiation (GO:0007289)2.57593363
57negative regulation of protein localization to cell surface (GO:2000009)2.55619336
58cellular response to growth hormone stimulus (GO:0071378)2.55564547
59axon extension (GO:0048675)2.53226271
60hemidesmosome assembly (GO:0031581)2.50069121
61nuclear pore organization (GO:0006999)2.48844884
62regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.48748287
63clathrin coat assembly (GO:0048268)2.48634716
64myelin assembly (GO:0032288)2.48070333
65glycosphingolipid biosynthetic process (GO:0006688)2.47741505
66positive regulation of interleukin-17 production (GO:0032740)2.46965435
67protein localization to endosome (GO:0036010)2.44543079
68dendrite morphogenesis (GO:0048813)2.42152919
69regulation of axon guidance (GO:1902667)2.41944533
70mitotic sister chromatid cohesion (GO:0007064)2.41736535
71establishment of protein localization to Golgi (GO:0072600)2.41036881
72production of molecular mediator involved in inflammatory response (GO:0002532)2.41009085
73striatum development (GO:0021756)2.40802000
74Leydig cell differentiation (GO:0033327)2.39805511
75cyclic nucleotide catabolic process (GO:0009214)2.39238861
76regulation of anoikis (GO:2000209)2.38002935
77Rap protein signal transduction (GO:0032486)2.36173722
78magnesium ion transport (GO:0015693)2.36066487
79response to nerve growth factor (GO:1990089)2.35610500
80cellular response to nerve growth factor stimulus (GO:1990090)2.35610500
81myelination in peripheral nervous system (GO:0022011)2.35512510
82peripheral nervous system axon ensheathment (GO:0032292)2.35512510
83membrane tubulation (GO:0097320)2.34814053
84regulation of myelination (GO:0031641)2.34322563
85membrane assembly (GO:0071709)2.33836738
86paraxial mesoderm development (GO:0048339)2.32765820
87desmosome organization (GO:0002934)2.32202645
88positive regulation of glial cell differentiation (GO:0045687)2.32064839
89pore complex assembly (GO:0046931)2.31830131
90positive regulation of T cell cytokine production (GO:0002726)2.31603085
91cytoplasmic mRNA processing body assembly (GO:0033962)2.31579897
92cellular potassium ion homeostasis (GO:0030007)2.31274001
93negative regulation of chondrocyte differentiation (GO:0032331)2.31182626
94neuron projection extension (GO:1990138)2.31128232
95positive regulation of dendritic spine morphogenesis (GO:0061003)2.30982892
96apical protein localization (GO:0045176)2.30218328
97protein targeting to Golgi (GO:0000042)2.30056909
98regulation of transforming growth factor beta2 production (GO:0032909)2.29904018
99collagen fibril organization (GO:0030199)2.29076739
100negative regulation of axon extension involved in axon guidance (GO:0048843)2.29034400
101regulation of histone H3-K27 methylation (GO:0061085)2.28710012
102chondrocyte development (GO:0002063)2.28416359
103negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.28082604
104regulation of clathrin-mediated endocytosis (GO:2000369)2.27732820
105protein palmitoylation (GO:0018345)2.26800435
106cell morphogenesis involved in neuron differentiation (GO:0048667)2.26082711
107positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.24893889
108synaptic vesicle exocytosis (GO:0016079)2.23099545
109retrograde transport, vesicle recycling within Golgi (GO:0000301)2.20905236
110cellular response to vitamin D (GO:0071305)2.20160923
111positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.19747646
112cell adhesion mediated by integrin (GO:0033627)2.19489688
113establishment of mitochondrion localization (GO:0051654)2.18885623
114cholesterol biosynthetic process (GO:0006695)2.18533457
115glycerophospholipid catabolic process (GO:0046475)2.18488272
116negative regulation of keratinocyte proliferation (GO:0010839)2.18121397
117postsynaptic membrane organization (GO:0001941)2.17698502
118myoblast fusion (GO:0007520)2.17652343
119regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.17215163
120central nervous system projection neuron axonogenesis (GO:0021952)2.17125139
121positive regulation of catenin import into nucleus (GO:0035413)2.17077969
122neuron cell-cell adhesion (GO:0007158)2.16176685
123mammary gland alveolus development (GO:0060749)2.15301153
124morphogenesis of an epithelial sheet (GO:0002011)2.15263161
125nucleus localization (GO:0051647)2.14983417
126regulation of collateral sprouting (GO:0048670)2.14736981
127regulation of memory T cell differentiation (GO:0043380)2.14692074
128regulation of protein polyubiquitination (GO:1902914)2.14125637
129positive regulation of cardiac muscle hypertrophy (GO:0010613)2.13970747
130positive regulation of muscle hypertrophy (GO:0014742)2.13970747
131virion attachment to host cell (GO:0019062)2.13871036
132adhesion of symbiont to host cell (GO:0044650)2.13871036
133response to methylmercury (GO:0051597)2.13149064
134positive regulation of astrocyte differentiation (GO:0048711)2.13065939
135positive regulation of protein autophosphorylation (GO:0031954)2.12495323
136negative regulation of fatty acid transport (GO:2000192)2.12048868
137vesicle coating (GO:0006901)2.10562774
138N-acetylglucosamine metabolic process (GO:0006044)2.10174271
139neuron remodeling (GO:0016322)2.10061831
140glycosylceramide metabolic process (GO:0006677)2.09533366
141lipid translocation (GO:0034204)2.08646365
142phospholipid translocation (GO:0045332)2.08646365
143positive regulation of gliogenesis (GO:0014015)2.08231724
144creatine metabolic process (GO:0006600)2.08010275
145negative regulation of axonogenesis (GO:0050771)2.07154766
146positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.06554284
147vesicle transport along microtubule (GO:0047496)2.06340716
148cytoskeleton-dependent cytokinesis (GO:0061640)2.06315818
149neuronal ion channel clustering (GO:0045161)2.05888525
150regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.05498868
151semaphorin-plexin signaling pathway (GO:0071526)2.05444307
152T-helper 1 type immune response (GO:0042088)2.05175342
153regulation of T-helper 2 cell differentiation (GO:0045628)2.05158539
154smooth muscle tissue development (GO:0048745)2.05132283
155organ growth (GO:0035265)2.04989889
156positive regulation of smooth muscle cell migration (GO:0014911)2.02155081
157long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)1.99609679
158activated T cell proliferation (GO:0050798)1.99527060
159regulation of somitogenesis (GO:0014807)1.98972574
160cortical cytoskeleton organization (GO:0030865)1.98753054
161glial cell differentiation (GO:0010001)1.97638971
162sterol biosynthetic process (GO:0016126)1.96924741
163regulation of activation of Janus kinase activity (GO:0010533)1.95223849
164metanephric nephron epithelium development (GO:0072243)1.94557540
165negative regulation of axon extension (GO:0030517)1.93667830
166iron ion import (GO:0097286)1.93643537
167dendritic spine morphogenesis (GO:0060997)1.93260157
168platelet-derived growth factor receptor signaling pathway (GO:0048008)1.92462499
169cortical actin cytoskeleton organization (GO:0030866)1.91905781
170axon development (GO:0061564)1.91711395
171polyol transport (GO:0015791)1.91158347
172membrane protein ectodomain proteolysis (GO:0006509)1.90959655
173transmission of nerve impulse (GO:0019226)1.90551136
174regulation of oligodendrocyte differentiation (GO:0048713)1.90363230
175regulation of lipoprotein metabolic process (GO:0050746)1.89978570
176cerebral cortex cell migration (GO:0021795)1.89511514
177isoprenoid biosynthetic process (GO:0008299)1.89476422
178negative regulation of exocytosis (GO:0045920)1.89352405
179positive regulation of T-helper cell differentiation (GO:0045624)1.88665817
180neuron recognition (GO:0008038)1.87025199
181regulation of homotypic cell-cell adhesion (GO:0034110)1.87007885
182retina vasculature morphogenesis in camera-type eye (GO:0061299)1.85930417
183neutrophil activation involved in immune response (GO:0002283)1.85922975

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.92363711
2GBX2_23144817_ChIP-Seq_PC3_Human3.14516180
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.95210489
4SALL1_21062744_ChIP-ChIP_HESCs_Human2.87361672
5CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.30764824
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.15150714
7CDX2_19796622_ChIP-Seq_MESCs_Mouse2.09229629
8ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89509442
9AR_21572438_ChIP-Seq_LNCaP_Human1.85006187
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.82876301
11JARID2_20064375_ChIP-Seq_MESCs_Mouse1.80765956
12SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.80584937
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.80304346
14POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78382188
15TAF15_26573619_Chip-Seq_HEK293_Human1.78240195
16VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77007192
17EZH2_22144423_ChIP-Seq_EOC_Human1.70976376
18TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.69532195
19FOXM1_26456572_ChIP-Seq_MCF-7_Human1.67917366
20* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.67488244
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.67438758
22TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.66723917
23TRIM28_21343339_ChIP-Seq_HEK293_Human1.62680620
24PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61730984
25WT1_19549856_ChIP-ChIP_CCG9911_Human1.60374468
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59572373
27ZNF217_24962896_ChIP-Seq_MCF-7_Human1.59523684
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.58988804
29AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.58420859
30PIAS1_25552417_ChIP-Seq_VCAP_Human1.57825359
31MTF2_20144788_ChIP-Seq_MESCs_Mouse1.56169671
32TBX3_20139965_ChIP-Seq_ESCs_Mouse1.54363179
33TBX3_20139965_ChIP-Seq_MESCs_Mouse1.54280345
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53343468
35EZH2_18974828_ChIP-Seq_MESCs_Mouse1.52710089
36RNF2_18974828_ChIP-Seq_MESCs_Mouse1.52710089
37SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.50589013
38SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.50492787
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.50180228
40* ER_23166858_ChIP-Seq_MCF-7_Human1.49289760
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46500129
42P300_19829295_ChIP-Seq_ESCs_Human1.45198388
43DROSHA_22980978_ChIP-Seq_HELA_Human1.44954841
44STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.44443399
45BRD4_25478319_ChIP-Seq_HGPS_Human1.44113541
46ESR1_20079471_ChIP-ChIP_T-47D_Human1.43856998
47ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.43211697
48SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.42910506
49EZH2_27304074_Chip-Seq_ESCs_Mouse1.42482358
50TP53_16413492_ChIP-PET_HCT116_Human1.41385262
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.41069720
52EED_16625203_ChIP-ChIP_MESCs_Mouse1.39544874
53* SMAD4_21799915_ChIP-Seq_A2780_Human1.38720940
54TP53_18474530_ChIP-ChIP_U2OS_Human1.38124953
55FLI1_27457419_Chip-Seq_LIVER_Mouse1.37370826
56KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.36974247
57RNF2_27304074_Chip-Seq_ESCs_Mouse1.34785936
58SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.34711450
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.33749405
60NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.33462327
61NRF2_20460467_ChIP-Seq_MEFs_Mouse1.33462327
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.33211128
63NANOG_18555785_Chip-Seq_ESCs_Mouse1.32715778
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.31154571
65AHR_22903824_ChIP-Seq_MCF-7_Human1.30455011
66* STAT3_23295773_ChIP-Seq_U87_Human1.30431129
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.29331011
68JARID2_20075857_ChIP-Seq_MESCs_Mouse1.27358529
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26886719
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.26594423
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.25717456
72SUZ12_27294783_Chip-Seq_ESCs_Mouse1.24532691
73YAP1_20516196_ChIP-Seq_MESCs_Mouse1.24230771
74KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.23414682
75CMYC_18555785_Chip-Seq_ESCs_Mouse1.22929944
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.20250843
77TP63_17297297_ChIP-ChIP_HaCaT_Human1.20203233
78NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.19102494
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19061753
80* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18119058
81CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17462065
82SUZ12_18555785_Chip-Seq_ESCs_Mouse1.15510118
83TOP2B_26459242_ChIP-Seq_MCF-7_Human1.14693280
84EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.14421662
85E2F1_18555785_Chip-Seq_ESCs_Mouse1.14315392
86* TCF4_23295773_ChIP-Seq_U87_Human1.14094628
87SOX9_26525672_Chip-Seq_HEART_Mouse1.13419718
88EZH2_27294783_Chip-Seq_NPCs_Mouse1.13169154
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.13125423
90PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13078217
91TCF4_18268006_ChIP-ChIP_LS174T_Human1.12526517
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11909197
93BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.11835474
94P53_22387025_ChIP-Seq_ESCs_Mouse1.11169707
95ISL1_27105846_Chip-Seq_CPCs_Mouse1.11119622
96DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.10961427
97EWS_26573619_Chip-Seq_HEK293_Human1.10804817
98NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.10796697
99FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.10724748
100KDM2B_26808549_Chip-Seq_REH_Human1.10637293
101STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.10587263
102CBX2_27304074_Chip-Seq_ESCs_Mouse1.10561630
103P300_18555785_Chip-Seq_ESCs_Mouse1.10088597
104* CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08650443
105ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.08314424
106CJUN_26792858_Chip-Seq_BT549_Human1.07439536
107Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.07391234
108EP300_21415370_ChIP-Seq_HL-1_Mouse1.07209358
109SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06236591
110CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.05687482
111CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05207218
112TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05023146
113FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.03994054
114RUNX_20019798_ChIP-Seq_JUKART_Human1.03207315
115VDR_24787735_ChIP-Seq_THP-1_Human1.03084072
116SOX2_21211035_ChIP-Seq_LN229_Gbm1.02908782
117EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02789107
118UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02737174
119WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02611733
120IGF1R_20145208_ChIP-Seq_DFB_Human1.02557892
121EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.01847061
122* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.01785740
123NFE2_27457419_Chip-Seq_LIVER_Mouse1.01170428
124BCAT_22108803_ChIP-Seq_LS180_Human1.00963752
125AR_25329375_ChIP-Seq_VCAP_Human0.99334790
126CTNNB1_20460455_ChIP-Seq_HCT116_Human0.99139956
127FUS_26573619_Chip-Seq_HEK293_Human0.98742550
128CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.98002341
129STAT3_18555785_Chip-Seq_ESCs_Mouse0.96735335
130OCT4_18555785_Chip-Seq_ESCs_Mouse0.96372584
131SOX2_18555785_Chip-Seq_ESCs_Mouse0.96234901
132STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.96165435
133RXR_22108803_ChIP-Seq_LS180_Human0.96078346

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination4.23291141
2MP0008057_abnormal_DNA_replication3.36732994
3MP0005171_absent_coat_pigmentation3.15842550
4MP0003136_yellow_coat_color2.87772373
5MP0003690_abnormal_glial_cell2.75472098
6MP0004742_abnormal_vestibular_system2.62848168
7MP0005409_darkened_coat_color2.55572371
8MP0000569_abnormal_digit_pigmentation2.50537170
9MP0004885_abnormal_endolymph2.36174408
10MP0003705_abnormal_hypodermis_morpholog2.29648458
11MP0003950_abnormal_plasma_membrane2.27021410
12MP0005275_abnormal_skin_tensile2.19477689
13MP0004270_analgesia2.18779639
14MP0001958_emphysema2.17197921
15MP0000778_abnormal_nervous_system2.15819972
16MP0008438_abnormal_cutaneous_collagen2.06004735
17MP0010678_abnormal_skin_adnexa2.05467294
18MP0003880_abnormal_central_pattern1.99075822
19MP0000383_abnormal_hair_follicle1.96224245
20MP0001486_abnormal_startle_reflex1.96175158
21MP0002254_reproductive_system_inflammat1.91914902
22MP0003634_abnormal_glial_cell1.85312036
23MP0003300_gastrointestinal_ulcer1.85268695
24MP0000427_abnormal_hair_cycle1.74627438
25MP0001299_abnormal_eye_distance/1.74428524
26MP0005423_abnormal_somatic_nervous1.72446858
27MP0000428_abnormal_craniofacial_morphol1.72406530
28MP0002090_abnormal_vision1.71637445
29MP0004381_abnormal_hair_follicle1.70911370
30MP0003045_fibrosis1.66217193
31MP0004859_abnormal_synaptic_plasticity1.65931569
32MP0003566_abnormal_cell_adhesion1.60261968
33MP0010352_gastrointestinal_tract_polyps1.59818474
34MP0005360_urolithiasis1.57194278
35MP0001502_abnormal_circadian_rhythm1.56078285
36MP0003329_amyloid_beta_deposits1.56048053
37MP0002138_abnormal_hepatobiliary_system1.53702152
38MP0002009_preneoplasia1.53688025
39MP0005503_abnormal_tendon_morphology1.52713829
40MP0002877_abnormal_melanocyte_morpholog1.51381977
41MP0003091_abnormal_cell_migration1.46425523
42MP0003935_abnormal_craniofacial_develop1.46155571
43MP0003303_peritoneal_inflammation1.44212050
44MP0006082_CNS_inflammation1.43031245
45MP0010234_abnormal_vibrissa_follicle1.41529408
46MP0002064_seizures1.38269179
47MP0001346_abnormal_lacrimal_gland1.37677396
48MP0008877_abnormal_DNA_methylation1.35682961
49MP0003787_abnormal_imprinting1.35565980
50MP0001485_abnormal_pinna_reflex1.35475898
51MP0001790_abnormal_immune_system1.34998478
52MP0005387_immune_system_phenotype1.34998478
53MP0003724_increased_susceptibility_to1.34694612
54MP0001661_extended_life_span1.33960729
55MP0002102_abnormal_ear_morphology1.33385328
56MP0000372_irregular_coat_pigmentation1.32010289
57MP0003632_abnormal_nervous_system1.31457165
58MP0000534_abnormal_ureter_morphology1.31320832
59MP0005257_abnormal_intraocular_pressure1.30915524
60MP0002909_abnormal_adrenal_gland1.30886889
61MP0004134_abnormal_chest_morphology1.29960515
62MP0002272_abnormal_nervous_system1.28431345
63MP0001348_abnormal_lacrimal_gland1.27713360
64MP0000537_abnormal_urethra_morphology1.27020876
65MP0005623_abnormal_meninges_morphology1.25640279
66MP0002184_abnormal_innervation1.25637227
67MP0001177_atelectasis1.24570689
68MP0000762_abnormal_tongue_morphology1.23647231
69MP0009384_cardiac_valve_regurgitation1.20829637
70MP0003635_abnormal_synaptic_transmissio1.18665144
71MP0004043_abnormal_pH_regulation1.16356099
72MP0002736_abnormal_nociception_after1.15888944
73MP0009745_abnormal_behavioral_response1.15668622
74MP0002896_abnormal_bone_mineralization1.15623019
75MP0003941_abnormal_skin_development1.14246169
76MP0000604_amyloidosis1.13296632
77MP0009046_muscle_twitch1.13293445
78MP0003631_nervous_system_phenotype1.12031910
79MP0002084_abnormal_developmental_patter1.11131884
80MP0003123_paternal_imprinting1.10865602
81MP0002998_abnormal_bone_remodeling1.10352026
82MP0000015_abnormal_ear_pigmentation1.10023731
83MP0003633_abnormal_nervous_system1.09936579
84MP0003283_abnormal_digestive_organ1.09427679
85MP0003942_abnormal_urinary_system1.09403253
86MP0003755_abnormal_palate_morphology1.07248490
87MP0003385_abnormal_body_wall1.06266072
88MP0002229_neurodegeneration1.05052975
89MP0005187_abnormal_penis_morphology1.04325538
90MP0003890_abnormal_embryonic-extraembry1.03203749
91MP0001851_eye_inflammation1.03144249
92MP0000579_abnormal_nail_morphology1.01943422
93MP0003861_abnormal_nervous_system0.98956493
94MP0002063_abnormal_learning/memory/cond0.98842757
95MP0000647_abnormal_sebaceous_gland0.95350523
96MP0000733_abnormal_muscle_development0.95218168
97MP0001905_abnormal_dopamine_level0.94886676
98MP0005671_abnormal_response_to0.94301860
99MP0000432_abnormal_head_morphology0.93957639
100MP0002177_abnormal_outer_ear0.93796698
101MP0001963_abnormal_hearing_physiology0.92681077
102MP0005000_abnormal_immune_tolerance0.92643646
103MP0004272_abnormal_basement_membrane0.92525980
104MP0003937_abnormal_limbs/digits/tail_de0.91541509
105MP0000566_synostosis0.91299472
106MP0002168_other_aberrant_phenotype0.91132480
107MP0002133_abnormal_respiratory_system0.89960726
108MP0005388_respiratory_system_phenotype0.89960726
109MP0002233_abnormal_nose_morphology0.89471225
110MP0003938_abnormal_ear_development0.88623996
111MP0004142_abnormal_muscle_tone0.88276702
112MP0004185_abnormal_adipocyte_glucose0.88107986
113MP0005410_abnormal_fertilization0.87658420
114MP0002067_abnormal_sensory_capabilities0.86590837
115MP0002108_abnormal_muscle_morphology0.86420583
116MP0002933_joint_inflammation0.85783527
117MP0003115_abnormal_respiratory_system0.85436278
118MP0002882_abnormal_neuron_morphology0.84840378
119MP0002734_abnormal_mechanical_nocicepti0.84759696
120MP0002572_abnormal_emotion/affect_behav0.84166847
121MP0005058_abnormal_lysosome_morphology0.84125693
122MP0001879_abnormal_lymphatic_vessel0.84110833
123MP0002152_abnormal_brain_morphology0.83356243
124MP0005310_abnormal_salivary_gland0.82961882
125MP0000955_abnormal_spinal_cord0.82486666
126MP0002876_abnormal_thyroid_physiology0.82066308
127MP0003868_abnormal_feces_composition0.81519148
128MP0002295_abnormal_pulmonary_circulatio0.80942729
129MP0000538_abnormal_urinary_bladder0.79587970
130MP0002060_abnormal_skin_morphology0.79325595
131MP0009780_abnormal_chondrocyte_physiolo0.79020876
132MP0009250_abnormal_appendicular_skeleto0.78739649
133MP0008569_lethality_at_weaning0.78045876
134MP0004924_abnormal_behavior0.77916113
135MP0005386_behavior/neurological_phenoty0.77916113
136MP0001915_intracranial_hemorrhage0.77490700
137MP0002166_altered_tumor_susceptibility0.77446637
138MP0002751_abnormal_autonomic_nervous0.76331668
139MP0005408_hypopigmentation0.76022009
140MP0001984_abnormal_olfaction0.75959679
141MP0003121_genomic_imprinting0.75541668
142MP0005551_abnormal_eye_electrophysiolog0.74894068
143MP0000613_abnormal_salivary_gland0.74401105
144MP0001440_abnormal_grooming_behavior0.74121751
145MP0004811_abnormal_neuron_physiology0.74038655
146MP0001286_abnormal_eye_development0.73598233
147MP0005197_abnormal_uvea_morphology0.73378868
148MP0000639_abnormal_adrenal_gland0.73255749
149MP0001188_hyperpigmentation0.72967789
150MP0004233_abnormal_muscle_weight0.72534964
151MP0001501_abnormal_sleep_pattern0.72466694
152MP0003943_abnormal_hepatobiliary_system0.71898717
153MP0000462_abnormal_digestive_system0.71722335
154MP0002066_abnormal_motor_capabilities/c0.70027449
155MP0003195_calcinosis0.69014830
156MP0002006_tumorigenesis0.67883071
157MP0000685_abnormal_immune_system0.67029164
158MP0003252_abnormal_bile_duct0.66515646
159MP0000026_abnormal_inner_ear0.66440966

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)5.05848790
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.05848790
3Tetraparesis (HP:0002273)4.67302058
4Visual hallucinations (HP:0002367)4.40642685
5Neurofibrillary tangles (HP:0002185)4.32489329
6Abnormality of the corticospinal tract (HP:0002492)3.89252844
7Parakeratosis (HP:0001036)3.50691094
8Onion bulb formation (HP:0003383)3.49036168
9Sensory axonal neuropathy (HP:0003390)3.28250584
10Metabolic alkalosis (HP:0200114)3.24562561
11Spastic diplegia (HP:0001264)3.16022443
12Cerebral inclusion bodies (HP:0100314)3.14705699
13Hypoplasia of the iris (HP:0007676)3.14694283
14Insidious onset (HP:0003587)3.11480910
15Termporal pattern (HP:0011008)3.11480910
16Autoimmune hemolytic anemia (HP:0001890)3.11464058
17Increased circulating renin level (HP:0000848)3.05105569
18Stomach cancer (HP:0012126)2.96503803
19Aplasia involving bones of the extremities (HP:0009825)2.93915868
20Aplasia involving bones of the upper limbs (HP:0009823)2.93915868
21Aplasia of the phalanges of the hand (HP:0009802)2.93915868
22Overgrowth (HP:0001548)2.92131028
23Arterial tortuosity (HP:0005116)2.90733294
24Hypomagnesemia (HP:0002917)2.87790180
25Testicular atrophy (HP:0000029)2.79557443
26Hypokalemic alkalosis (HP:0001949)2.75258441
27Peripheral hypomyelination (HP:0007182)2.75062063
28Vascular tortuosity (HP:0004948)2.74388807
29Abnormal auditory evoked potentials (HP:0006958)2.66697452
30Increased neuronal autofluorescent lipopigment (HP:0002074)2.60950209
31Protrusio acetabuli (HP:0003179)2.59582213
32Spastic gait (HP:0002064)2.59389950
33Blue irides (HP:0000635)2.47952102
34Premature rupture of membranes (HP:0001788)2.46330248
35Infantile muscular hypotonia (HP:0008947)2.44276480
36Segmental peripheral demyelination/remyelination (HP:0003481)2.41822337
37Supranuclear gaze palsy (HP:0000605)2.39563814
38Coronal craniosynostosis (HP:0004440)2.37066824
39Papillary thyroid carcinoma (HP:0002895)2.36966202
40Atrophic scars (HP:0001075)2.35577633
41Ankle clonus (HP:0011448)2.35522408
42Scanning speech (HP:0002168)2.30931035
43Heterotopia (HP:0002282)2.30168862
44Aortic dissection (HP:0002647)2.29935700
45White forelock (HP:0002211)2.28587394
46Decreased motor nerve conduction velocity (HP:0003431)2.28223686
47Thickened helices (HP:0000391)2.24389937
48Autoimmune thrombocytopenia (HP:0001973)2.23260633
49Megalencephaly (HP:0001355)2.23020011
50Clumsiness (HP:0002312)2.21114401
51Central scotoma (HP:0000603)2.20030064
52Widely spaced teeth (HP:0000687)2.18854027
53Lower limb muscle weakness (HP:0007340)2.17839338
54Shallow orbits (HP:0000586)2.17523136
55Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.17294063
56Astrocytoma (HP:0009592)2.15747552
57Abnormality of the astrocytes (HP:0100707)2.15747552
58Chin dimple (HP:0010751)2.14405283
59Slow saccadic eye movements (HP:0000514)2.11893741
60Intention tremor (HP:0002080)2.11840537
61Macroorchidism (HP:0000053)2.11454866
62Dysmetria (HP:0001310)2.09464361
63Submucous cleft hard palate (HP:0000176)2.07362274
64Action tremor (HP:0002345)2.05350680
65Bell-shaped thorax (HP:0001591)2.04982165
66Aqueductal stenosis (HP:0002410)2.04010199
67Progressive sensorineural hearing impairment (HP:0000408)2.02449564
68Dyschromatopsia (HP:0007641)2.01854071
69Ankyloglossia (HP:0010296)2.01366421
70Osteolytic defects of the hand bones (HP:0009699)2.00796206
71Osteolytic defects of the phalanges of the hand (HP:0009771)2.00796206
72Akinesia (HP:0002304)1.99950904
73Increased cerebral lipofuscin (HP:0011813)1.98874192
74Patchy hypopigmentation of hair (HP:0011365)1.98607845
75Asymmetry of the thorax (HP:0001555)1.95462548
76Intellectual disability, moderate (HP:0002342)1.95144575
77Alacrima (HP:0000522)1.94972008
78Anteriorly placed anus (HP:0001545)1.94354175
79Drooling (HP:0002307)1.93813909
80Excessive salivation (HP:0003781)1.93813909
81Pulmonic stenosis (HP:0001642)1.91942852
82Curly hair (HP:0002212)1.91911646
83Abnormality of incisor morphology (HP:0011063)1.91681461
84Urinary bladder sphincter dysfunction (HP:0002839)1.91562575
85Hypophosphatemic rickets (HP:0004912)1.91323933
86Spinal rigidity (HP:0003306)1.89788706
87Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.89407305
88Congenital sensorineural hearing impairment (HP:0008527)1.88047602
89Abnormality of magnesium homeostasis (HP:0004921)1.87510639
90Premature skin wrinkling (HP:0100678)1.87013017
91Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.86717413
92Cubitus valgus (HP:0002967)1.86235399
93Abnormality of chloride homeostasis (HP:0011422)1.86000246
94Renovascular hypertension (HP:0100817)1.83201640
95Retinal dysplasia (HP:0007973)1.82897937
96Enlarged penis (HP:0000040)1.82589253
97Bladder diverticulum (HP:0000015)1.82378637
98Abnormality of oral frenula (HP:0000190)1.81740159
99Urinary urgency (HP:0000012)1.81663048
100Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.81532029
101Subacute progressive viral hepatitis (HP:0006572)1.81112072
102Broad metatarsal (HP:0001783)1.80298933
103Mitral stenosis (HP:0001718)1.78913224
104Stomatitis (HP:0010280)1.78784867
105Abnormality of salivation (HP:0100755)1.78118828
106Glioma (HP:0009733)1.77888791
107Long nose (HP:0003189)1.76995892
108Thick nail (HP:0001805)1.76716254
109Bowel diverticulosis (HP:0005222)1.76589516
110Short nail (HP:0001799)1.75232988
111Cupped ear (HP:0000378)1.74849439
112Pheochromocytoma (HP:0002666)1.74590278
113Menstrual irregularities (HP:0000858)1.74160264
114Abnormality of the ischium (HP:0003174)1.73374214
115Deep philtrum (HP:0002002)1.71852549
116Buphthalmos (HP:0000557)1.71701141
117Ependymoma (HP:0002888)1.71498265
118Relative macrocephaly (HP:0004482)1.70811109
119Conical tooth (HP:0000698)1.70784823
120Rhabdomyosarcoma (HP:0002859)1.70548877
121Soft skin (HP:0000977)1.70379476
122Neonatal short-limb short stature (HP:0008921)1.68946668
123Stridor (HP:0010307)1.68894928
124Focal motor seizures (HP:0011153)1.68743146
125Vertebral arch anomaly (HP:0008438)1.68532336
126Autoamputation (HP:0001218)1.68107536
127Steppage gait (HP:0003376)1.68068186
128Ankle contracture (HP:0006466)1.68051777
129Abnormal drinking behavior (HP:0030082)1.67874326
130Polydipsia (HP:0001959)1.67874326
131Partial agenesis of the corpus callosum (HP:0001338)1.67831725
132Synostosis involving the elbow (HP:0003938)1.67112560
133Humeroradial synostosis (HP:0003041)1.67112560
134Abnormality of dentin (HP:0010299)1.66521472
135Neoplasm of the thyroid gland (HP:0100031)1.66243247
136Absent frontal sinuses (HP:0002688)1.66070406
137Femoral bowing (HP:0002980)1.65972406
138Spastic tetraparesis (HP:0001285)1.65726576
139Lower limb amyotrophy (HP:0007210)1.65687917
140Anhidrosis (HP:0000970)1.65365372
141Persistence of primary teeth (HP:0006335)1.62295849
142Absent speech (HP:0001344)1.62185208
143Wormian bones (HP:0002645)1.62121090
144Abnormality of T cell number (HP:0011839)1.61835697
145Hyperventilation (HP:0002883)1.60503588
146Polyuria (HP:0000103)1.60016770
147Aplasia/Hypoplasia of the fibula (HP:0006492)1.60013097
148Medulloblastoma (HP:0002885)1.59617757
149Mixed hearing impairment (HP:0000410)1.58742561
150Scotoma (HP:0000575)1.58656403
151Large earlobe (HP:0009748)1.58575358
152Peritonitis (HP:0002586)1.57972990
153Peripheral demyelination (HP:0011096)1.57862885
154Abnormality of the nasal septum (HP:0000419)1.57539307
155Chronic diarrhea (HP:0002028)1.57278896
156Decreased lacrimation (HP:0000633)1.57048924
157Adrenal hypoplasia (HP:0000835)1.56517050
158Mitral valve prolapse (HP:0001634)1.56464131
159Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.55737287
160Fibular hypoplasia (HP:0003038)1.54139866
161Wide anterior fontanel (HP:0000260)1.53411086
162Transitional cell carcinoma of the bladder (HP:0006740)1.53129154
163Thyroid carcinoma (HP:0002890)1.53126672
164Abnormality of the distal phalanx of the thumb (HP:0009617)1.51487363
165Abnormality of pain sensation (HP:0010832)1.50937076
166Impaired pain sensation (HP:0007328)1.50937076
167Wrist flexion contracture (HP:0001239)1.49554176
168Bladder carcinoma (HP:0002862)1.49178795
169Bladder neoplasm (HP:0009725)1.49178795
170Abnormality of the frontal sinuses (HP:0002687)1.48647823
171Neoplasm of the oral cavity (HP:0100649)1.48095147
172Cutaneous finger syndactyly (HP:0010554)1.46134993
173Missing ribs (HP:0000921)1.45028058
174Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.43529054

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.01223638
2OXSR13.54921072
3PKN23.15406428
4EPHB13.06919776
5WNK42.54329083
6FGFR22.43171360
7PKN12.33727864
8AKT32.26553025
9NEK12.23365972
10WNK12.05376416
11CASK1.78188213
12TNIK1.77714859
13WEE11.76926292
14BCR1.76173604
15MAP3K141.71892290
16PTK21.70354004
17CSNK1A1L1.69830686
18LATS21.68697376
19MARK11.68060687
20PBK1.49236291
21FGFR11.47876071
22MET1.47389671
23WNK31.42439246
24FGR1.38811274
25CSNK1G11.38199770
26NEK61.38096516
27EPHA31.33345002
28MAP3K121.32066804
29NUAK11.28527911
30EIF2AK11.27174633
31SGK4941.26802820
32SGK2231.26802820
33RPS6KB11.24303261
34PRKCQ1.23509115
35NTRK11.21884364
36CSNK1G31.19992929
37IRAK11.18336477
38JAK11.17367235
39TXK1.14670909
40CSNK1G21.14335709
41PDGFRB1.13498724
42DMPK1.12409649
43MAP3K131.08617289
44PNCK1.07317086
45FLT31.07288466
46MAPKAPK51.07013271
47MAP3K21.06807234
48CAMK2G1.06275395
49CLK11.06271079
50BMPR1B1.06189978
51LATS11.06132015
52NEK91.06114411
53ERBB31.04055072
54IRAK21.02271018
55TSSK61.01302985
56BRD41.01182424
57ROCK21.01089659
58RET1.00061656
59CAMK1G0.99745448
60STK38L0.99598998
61MAP3K90.95206842
62ICK0.94043229
63FRK0.93505847
64EPHA40.92715892
65EPHA20.91980096
66MST40.91695986
67PAK30.88881913
68PIK3CA0.88836963
69NTRK20.88285428
70CCNB10.88059940
71CAMK2B0.87086154
72KSR10.86550989
73PAK60.85951059
74MARK20.84067658
75CSK0.83735528
76NLK0.81041880
77ERBB40.80565418
78ITK0.80539888
79STK110.79139288
80BLK0.78868610
81FGFR30.76650456
82FYN0.75463138
83DDR20.74779204
84MAP3K40.74436088
85BMX0.74389215
86CDK50.73834883
87PRKCH0.73398767
88TRIB30.72565743
89LIMK10.70915684
90PRPF4B0.70674649
91PRKCE0.70254020
92TRPM70.69546300
93GSK3A0.68787956
94STK380.67891810
95PRKD20.67425911
96MTOR0.67320063
97SGK10.66017376
98MST1R0.65636735
99PDPK10.63722018
100STK30.63533548
101SCYL20.62989067
102INSRR0.62105969
103SGK30.62098041
104TYRO30.61685580
105JAK30.60754732
106LCK0.60261384
107TRIM280.60203008
108BRSK20.59809770
109PLK20.59020947
110YES10.59000438
111PRKD10.58696157
112RIPK40.58564637
113FGFR40.58304340
114INSR0.58279957
115FER0.58271067
116CAMK1D0.58093734
117TAF10.57428521
118MINK10.56663800
119HCK0.56009548
120UHMK10.55569658
121IRAK40.55297118
122FES0.54236877
123BMPR20.52176980
124PAK20.51647340
125MAPK100.51612707
126TGFBR10.51568509
127IKBKE0.51383629
128CAMK2D0.51101065
129CDK30.50745465
130CAMK2A0.50274095
131NEK20.50115953
132MAPK130.49578748
133ABL10.49215879
134PLK40.48909087
135RPS6KA50.48857094
136ROCK10.48818431
137PDGFRA0.48072954
138MYLK0.45991750
139CSNK1D0.45865213
140BRSK10.45829527
141IKBKB0.45736010
142SGK20.45608275
143NTRK30.45460170
144PDK10.44429802
145EPHB20.43940248
146ATM0.43892710
147CSNK1E0.43874986
148HIPK20.43511192
149EIF2AK30.43249713
150PRKDC0.38661388
151MELK0.37413932
152CDK90.37152533
153MKNK20.36430884
154BRAF0.34651712

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001002.46802367
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.41703817
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99042656
4Hippo signaling pathway_Homo sapiens_hsa043901.73902333
5Allograft rejection_Homo sapiens_hsa053301.72930732
6Axon guidance_Homo sapiens_hsa043601.67645562
7Graft-versus-host disease_Homo sapiens_hsa053321.67138265
8Autoimmune thyroid disease_Homo sapiens_hsa053201.64915039
9Ether lipid metabolism_Homo sapiens_hsa005651.64348494
10Fatty acid elongation_Homo sapiens_hsa000621.63210506
11Endometrial cancer_Homo sapiens_hsa052131.62846823
12Adherens junction_Homo sapiens_hsa045201.61159401
13Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.57242834
14Long-term potentiation_Homo sapiens_hsa047201.54663660
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.42712343
16Sphingolipid metabolism_Homo sapiens_hsa006001.41671818
17Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.41279171
18TGF-beta signaling pathway_Homo sapiens_hsa043501.36862544
19Dorso-ventral axis formation_Homo sapiens_hsa043201.35344964
20MicroRNAs in cancer_Homo sapiens_hsa052061.29579490
21Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.26170576
22mTOR signaling pathway_Homo sapiens_hsa041501.24233269
23Insulin secretion_Homo sapiens_hsa049111.23508602
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.21976434
25N-Glycan biosynthesis_Homo sapiens_hsa005101.21298064
26Wnt signaling pathway_Homo sapiens_hsa043101.20585773
27Estrogen signaling pathway_Homo sapiens_hsa049151.20174557
28Thyroid hormone signaling pathway_Homo sapiens_hsa049191.18677365
29Thyroid hormone synthesis_Homo sapiens_hsa049181.16285340
30Colorectal cancer_Homo sapiens_hsa052101.15501654
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.14474297
32Melanoma_Homo sapiens_hsa052181.13155618
33Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.12679025
34Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.12592309
35Chronic myeloid leukemia_Homo sapiens_hsa052201.12482380
36NF-kappa B signaling pathway_Homo sapiens_hsa040641.12255564
37Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.11660868
38T cell receptor signaling pathway_Homo sapiens_hsa046601.11541613
39Malaria_Homo sapiens_hsa051441.11521219
40Renal cell carcinoma_Homo sapiens_hsa052111.10180990
41mRNA surveillance pathway_Homo sapiens_hsa030151.10057692
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.09881205
43Thyroid cancer_Homo sapiens_hsa052161.08851710
44Hedgehog signaling pathway_Homo sapiens_hsa043401.06752591
45Amphetamine addiction_Homo sapiens_hsa050311.06651603
46Glutamatergic synapse_Homo sapiens_hsa047241.04373331
47Sphingolipid signaling pathway_Homo sapiens_hsa040711.03036741
48Chemokine signaling pathway_Homo sapiens_hsa040621.02136849
49Prolactin signaling pathway_Homo sapiens_hsa049171.01666312
50Sulfur metabolism_Homo sapiens_hsa009201.00388904
51ECM-receptor interaction_Homo sapiens_hsa045120.99860529
52Basal cell carcinoma_Homo sapiens_hsa052170.99360111
53Rheumatoid arthritis_Homo sapiens_hsa053230.99275796
54ErbB signaling pathway_Homo sapiens_hsa040120.98509473
55Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.97630985
56Intestinal immune network for IgA production_Homo sapiens_hsa046720.96582365
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.96354918
58Gap junction_Homo sapiens_hsa045400.95155207
59Dilated cardiomyopathy_Homo sapiens_hsa054140.95075094
60Lysine degradation_Homo sapiens_hsa003100.95038696
61Morphine addiction_Homo sapiens_hsa050320.94866097
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.94587228
63Small cell lung cancer_Homo sapiens_hsa052220.92769070
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92245108
65Choline metabolism in cancer_Homo sapiens_hsa052310.90508298
66Circadian rhythm_Homo sapiens_hsa047100.90426241
67Mineral absorption_Homo sapiens_hsa049780.90394574
68Serotonergic synapse_Homo sapiens_hsa047260.90392419
69Melanogenesis_Homo sapiens_hsa049160.90296876
70Ras signaling pathway_Homo sapiens_hsa040140.90150575
71AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.89954823
72Gastric acid secretion_Homo sapiens_hsa049710.87192168
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.87052536
74Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.86823462
75Oocyte meiosis_Homo sapiens_hsa041140.86406758
76Histidine metabolism_Homo sapiens_hsa003400.85635410
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84208155
78GABAergic synapse_Homo sapiens_hsa047270.83417882
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.83095895
80Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82956763
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82716414
82Osteoclast differentiation_Homo sapiens_hsa043800.81602425
83Pathways in cancer_Homo sapiens_hsa052000.81523868
84B cell receptor signaling pathway_Homo sapiens_hsa046620.81402549
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81400029
86Non-small cell lung cancer_Homo sapiens_hsa052230.81055352
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80849422
88Long-term depression_Homo sapiens_hsa047300.80017321
89Nitrogen metabolism_Homo sapiens_hsa009100.79150642
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.78929673
91Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.78372853
92Asthma_Homo sapiens_hsa053100.78087529
93Toll-like receptor signaling pathway_Homo sapiens_hsa046200.77884575
94Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.77821457
95Cocaine addiction_Homo sapiens_hsa050300.77465045
96Leukocyte transendothelial migration_Homo sapiens_hsa046700.77281141
97Focal adhesion_Homo sapiens_hsa045100.77207829
98Butanoate metabolism_Homo sapiens_hsa006500.76391041
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.76140710
100Endocytosis_Homo sapiens_hsa041440.75742981
101Measles_Homo sapiens_hsa051620.75427287
102Renin secretion_Homo sapiens_hsa049240.75053864
103Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74937944
104Selenocompound metabolism_Homo sapiens_hsa004500.74438395
105Prostate cancer_Homo sapiens_hsa052150.74015367
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.72816594
107Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.72492924
108Taste transduction_Homo sapiens_hsa047420.72438994
109Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.72282928
110Salivary secretion_Homo sapiens_hsa049700.72075601
111Basal transcription factors_Homo sapiens_hsa030220.71156095
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.70270104
113Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70147187
114Viral myocarditis_Homo sapiens_hsa054160.69644344
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.69458162
116Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69345215
117Type I diabetes mellitus_Homo sapiens_hsa049400.69308750
118NOD-like receptor signaling pathway_Homo sapiens_hsa046210.68143166
119VEGF signaling pathway_Homo sapiens_hsa043700.67816608
120Protein digestion and absorption_Homo sapiens_hsa049740.67808637
121Cholinergic synapse_Homo sapiens_hsa047250.67314874
122Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67275263
123African trypanosomiasis_Homo sapiens_hsa051430.67197120
124Salmonella infection_Homo sapiens_hsa051320.66426967
125TNF signaling pathway_Homo sapiens_hsa046680.66397542
126MAPK signaling pathway_Homo sapiens_hsa040100.66076366
127GnRH signaling pathway_Homo sapiens_hsa049120.65646193
128Glioma_Homo sapiens_hsa052140.65377525
129Toxoplasmosis_Homo sapiens_hsa051450.65028925
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.64501482
131Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.64157177
132Vitamin digestion and absorption_Homo sapiens_hsa049770.64036977
133Inositol phosphate metabolism_Homo sapiens_hsa005620.63785148
134Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63607754
135Hematopoietic cell lineage_Homo sapiens_hsa046400.63425101
136Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62989407
137Pancreatic secretion_Homo sapiens_hsa049720.61798075
138cAMP signaling pathway_Homo sapiens_hsa040240.61144937
139Primary immunodeficiency_Homo sapiens_hsa053400.60614013
140Tight junction_Homo sapiens_hsa045300.60047115
141Leishmaniasis_Homo sapiens_hsa051400.59964099
142Fatty acid biosynthesis_Homo sapiens_hsa000610.57810441
143Rap1 signaling pathway_Homo sapiens_hsa040150.57523510
144Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56998543
145Nicotine addiction_Homo sapiens_hsa050330.56925344
146Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.56910126
147Platelet activation_Homo sapiens_hsa046110.56754157
148Circadian entrainment_Homo sapiens_hsa047130.56677230
149Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56461937
150Type II diabetes mellitus_Homo sapiens_hsa049300.55458958
151Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55095907
152Hepatitis C_Homo sapiens_hsa051600.55016872
153Lysosome_Homo sapiens_hsa041420.54855903
154Amoebiasis_Homo sapiens_hsa051460.53813088
155Proteoglycans in cancer_Homo sapiens_hsa052050.52819760
156Pancreatic cancer_Homo sapiens_hsa052120.52271802
157Dopaminergic synapse_Homo sapiens_hsa047280.51812756
158PI3K-Akt signaling pathway_Homo sapiens_hsa041510.51628692

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