ANKRA2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane organization (GO:0097090)9.15306687
2presynaptic membrane assembly (GO:0097105)7.63408684
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.65742394
4gamma-aminobutyric acid transport (GO:0015812)5.55736631
5nonmotile primary cilium assembly (GO:0035058)4.73511107
6neuron cell-cell adhesion (GO:0007158)4.62110949
7mannosylation (GO:0097502)4.54401498
8ionotropic glutamate receptor signaling pathway (GO:0035235)4.39169106
9protein localization to synapse (GO:0035418)4.23054359
10axoneme assembly (GO:0035082)4.14372775
11synaptic vesicle exocytosis (GO:0016079)4.13365318
12positive regulation of synapse assembly (GO:0051965)4.09972386
13glutamate receptor signaling pathway (GO:0007215)4.02017247
14protein localization to cilium (GO:0061512)4.00905723
15synaptic transmission, glutamatergic (GO:0035249)3.97811135
16protein-cofactor linkage (GO:0018065)3.95572470
17glutamate secretion (GO:0014047)3.95078816
18behavioral response to nicotine (GO:0035095)3.91938561
19regulation of synaptic vesicle exocytosis (GO:2000300)3.90530290
20epithelial cilium movement (GO:0003351)3.90104565
21positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.85848335
22mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.85848335
23regulation of cilium movement (GO:0003352)3.84312215
24negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.83422297
25neuron recognition (GO:0008038)3.75299955
26layer formation in cerebral cortex (GO:0021819)3.71021000
27membrane assembly (GO:0071709)3.70501699
28regulation of synaptic vesicle transport (GO:1902803)3.66570781
29regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.65339479
30regulation of long-term neuronal synaptic plasticity (GO:0048169)3.58557490
31epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.55403637
32positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.54631892
33neuron-neuron synaptic transmission (GO:0007270)3.52577284
34vocalization behavior (GO:0071625)3.52379732
35negative regulation of synaptic transmission, GABAergic (GO:0032229)3.51048355
36regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.50400389
37synaptic vesicle maturation (GO:0016188)3.47961628
38intraciliary transport (GO:0042073)3.47006958
39positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.46508574
40cilium movement (GO:0003341)3.44202095
41regulation of feeding behavior (GO:0060259)3.40840071
42retinal rod cell development (GO:0046548)3.39949997
43regulation of synapse structural plasticity (GO:0051823)3.39599917
44cilium morphogenesis (GO:0060271)3.32716102
45platelet dense granule organization (GO:0060155)3.32444822
46protein targeting to Golgi (GO:0000042)3.31620349
47response to pheromone (GO:0019236)3.26621787
48pyrimidine nucleobase catabolic process (GO:0006208)3.25250458
49pyrimidine dimer repair (GO:0006290)3.24640679
50cilium organization (GO:0044782)3.23836908
51photoreceptor cell development (GO:0042461)3.21739023
52chaperone-mediated protein transport (GO:0072321)3.21302802
53retinal cone cell development (GO:0046549)3.20862430
54neural tube formation (GO:0001841)3.17045508
55cilium assembly (GO:0042384)3.16804133
56mitochondrial fragmentation involved in apoptotic process (GO:0043653)3.16676406
57exploration behavior (GO:0035640)3.16623323
58gamma-aminobutyric acid signaling pathway (GO:0007214)3.15274634
59cellular response to leptin stimulus (GO:0044320)3.14933805
60activated T cell proliferation (GO:0050798)3.13126488
61postsynaptic membrane organization (GO:0001941)3.11113087
62establishment of protein localization to Golgi (GO:0072600)3.10475480
63S-adenosylmethionine metabolic process (GO:0046500)3.09895196
64regulation of neuronal synaptic plasticity (GO:0048168)3.08943017
65positive regulation of mitochondrial fission (GO:0090141)3.08708633
66neurotransmitter-gated ion channel clustering (GO:0072578)3.07927588
67establishment of mitochondrion localization (GO:0051654)3.06980876
68L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.06211324
69protein localization to Golgi apparatus (GO:0034067)3.05256681
70L-fucose catabolic process (GO:0042355)3.05104045
71fucose catabolic process (GO:0019317)3.05104045
72L-fucose metabolic process (GO:0042354)3.05104045
73neuronal action potential propagation (GO:0019227)3.03784166
74negative regulation of microtubule polymerization (GO:0031115)3.03586419
75positive regulation of synaptic transmission, GABAergic (GO:0032230)3.02492422
76eye photoreceptor cell development (GO:0042462)3.02066529
77regulation of glutamate receptor signaling pathway (GO:1900449)3.01000951
78locomotory exploration behavior (GO:0035641)2.98231549
79behavioral response to ethanol (GO:0048149)2.98174910
80regulation of excitatory postsynaptic membrane potential (GO:0060079)2.97182832
81regulation of synapse assembly (GO:0051963)2.97157867
82neuron fate determination (GO:0048664)2.95812716
83positive regulation of pseudopodium assembly (GO:0031274)2.95803623
84short-term memory (GO:0007614)2.95256342
85positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.93962891
86regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.93417285
87regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.92943616
88histone H3-K36 demethylation (GO:0070544)2.92276187
89protein polyglutamylation (GO:0018095)2.89484444
90positive regulation of neurotransmitter secretion (GO:0001956)2.88811343
91synapse assembly (GO:0007416)2.88773690
92GPI anchor biosynthetic process (GO:0006506)2.88692804
93synaptic vesicle docking involved in exocytosis (GO:0016081)2.86527665
94intra-Golgi vesicle-mediated transport (GO:0006891)2.86070333
95positive regulation of dendrite morphogenesis (GO:0050775)2.85843151
96regulation of postsynaptic membrane potential (GO:0060078)2.85680947
97calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.85513952
98regulation of vesicle fusion (GO:0031338)2.85103255
99retrograde transport, vesicle recycling within Golgi (GO:0000301)2.83616040
100G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.82642186
101preassembly of GPI anchor in ER membrane (GO:0016254)2.82615727
102central nervous system projection neuron axonogenesis (GO:0021952)2.82391544
103photoreceptor cell maintenance (GO:0045494)2.81528615
104membrane hyperpolarization (GO:0060081)2.80719921
105positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.80317988
106G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.79665567
107retinal ganglion cell axon guidance (GO:0031290)2.77495796
108positive regulation of membrane potential (GO:0045838)2.77403287
109RNA destabilization (GO:0050779)2.76206149
110negative regulation of response to food (GO:0032096)2.75837652
111negative regulation of appetite (GO:0032099)2.75837652
112protein complex biogenesis (GO:0070271)2.75229723
113sequestering of actin monomers (GO:0042989)2.75140268
114regulation of protein glycosylation (GO:0060049)2.73819821
115regulation of synapse organization (GO:0050807)2.73349949
116amino acid salvage (GO:0043102)2.72913581
117L-methionine salvage (GO:0071267)2.72913581
118L-methionine biosynthetic process (GO:0071265)2.72913581
119regulation of development, heterochronic (GO:0040034)2.72116830
120regulation of microtubule-based movement (GO:0060632)2.71719459
121mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.71193316
122behavioral defense response (GO:0002209)2.70680043
123behavioral fear response (GO:0001662)2.70680043
124positive regulation of oligodendrocyte differentiation (GO:0048714)2.68441401
125positive regulation of synapse maturation (GO:0090129)2.67885462
126fucosylation (GO:0036065)2.67880860
127tachykinin receptor signaling pathway (GO:0007217)2.65873555
128negative regulation of membrane potential (GO:0045837)2.65649161
129magnesium ion transport (GO:0015693)2.64522684
130pyrimidine ribonucleoside catabolic process (GO:0046133)2.64517846
131regulation of synaptic transmission, glutamatergic (GO:0051966)2.64265069
132DNA deamination (GO:0045006)2.63933510
133heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.63568383
134histone H2A acetylation (GO:0043968)2.63383528
135mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.63324682
136mitochondrial respiratory chain complex I assembly (GO:0032981)2.63324682
137NADH dehydrogenase complex assembly (GO:0010257)2.63324682
138axonal fasciculation (GO:0007413)2.62376751
139ATP synthesis coupled proton transport (GO:0015986)2.60813666
140energy coupled proton transport, down electrochemical gradient (GO:0015985)2.60813666
141proline transport (GO:0015824)2.60580790
142cellular ketone body metabolic process (GO:0046950)2.59835041
143regulation of synaptic transmission, GABAergic (GO:0032228)2.59041975
144transmission of nerve impulse (GO:0019226)2.58885146
145cellular potassium ion homeostasis (GO:0030007)2.58663459
146mitochondrion transport along microtubule (GO:0047497)2.58564156
147establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.58564156
148phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.58550438
149inositol phosphate catabolic process (GO:0071545)2.55923312
150GPI anchor metabolic process (GO:0006505)2.54865149
151regulation of microtubule polymerization (GO:0031113)2.54679952
152negative regulation of mast cell activation (GO:0033004)2.54070944
153anterograde axon cargo transport (GO:0008089)2.53815292
154long-term memory (GO:0007616)2.52893959
155positive regulation of neurotransmitter transport (GO:0051590)2.52510679
156positive regulation of dendritic spine development (GO:0060999)2.52430588
157auditory behavior (GO:0031223)2.52415790
158mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.52249656
159C-terminal protein lipidation (GO:0006501)2.52011768
160regulation of pseudopodium assembly (GO:0031272)2.51741071
161regulation of dendritic spine morphogenesis (GO:0061001)2.51739546
162nucleobase catabolic process (GO:0046113)2.51015456
163regulation of neurotransmitter secretion (GO:0046928)2.50768504
164negative regulation of neurotransmitter transport (GO:0051589)2.50181908
165fear response (GO:0042596)2.50104885
166nucleotide transmembrane transport (GO:1901679)2.49990304
167inositol phosphate dephosphorylation (GO:0046855)2.48270467
168phosphorylated carbohydrate dephosphorylation (GO:0046838)2.48270467
169positive regulation of dendrite development (GO:1900006)2.48214133
170vesicle localization (GO:0051648)2.47873814
171regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.47754985
172inner ear receptor stereocilium organization (GO:0060122)2.45944957
173mechanosensory behavior (GO:0007638)2.45085974
174glycolipid biosynthetic process (GO:0009247)2.44401131
175regulation of regulatory T cell differentiation (GO:0045589)2.43217927
176histone H2A ubiquitination (GO:0033522)2.40971840
177cytidine deamination (GO:0009972)2.39796201
178cytidine metabolic process (GO:0046087)2.39796201
179cytidine catabolic process (GO:0006216)2.39796201
180response to leptin (GO:0044321)2.39236056
181protein K48-linked ubiquitination (GO:0070936)2.39140256
182cilium or flagellum-dependent cell motility (GO:0001539)2.38847365
183regulation of glucokinase activity (GO:0033131)2.37950588
184regulation of hexokinase activity (GO:1903299)2.37950588

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.27279640
2GBX2_23144817_ChIP-Seq_PC3_Human3.84787403
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.45244579
4TAF15_26573619_Chip-Seq_HEK293_Human2.87709654
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87370022
6CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.61191003
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.55497028
8REST_21632747_ChIP-Seq_MESCs_Mouse2.54582477
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.40474044
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.33478464
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.29981000
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.25920940
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.19234080
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.11894946
15FUS_26573619_Chip-Seq_HEK293_Human2.10353930
16CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.09022165
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08569418
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.07905841
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.06438468
20* REST_18959480_ChIP-ChIP_MESCs_Mouse2.05551415
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.02060641
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98579622
23AR_21572438_ChIP-Seq_LNCaP_Human1.98030359
24* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.92901358
25MTF2_20144788_ChIP-Seq_MESCs_Mouse1.92670727
26VDR_22108803_ChIP-Seq_LS180_Human1.92330081
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.91238791
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.90410525
29EZH2_27294783_Chip-Seq_ESCs_Mouse1.88232960
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.84840750
31* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.83917359
32SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.79108099
33PCGF2_27294783_Chip-Seq_ESCs_Mouse1.77501557
34IGF1R_20145208_ChIP-Seq_DFB_Human1.77287598
35EZH2_18974828_ChIP-Seq_MESCs_Mouse1.76169367
36RNF2_18974828_ChIP-Seq_MESCs_Mouse1.76169367
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.71983947
38P300_19829295_ChIP-Seq_ESCs_Human1.70718910
39GABP_17652178_ChIP-ChIP_JURKAT_Human1.65709569
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.64088920
41RARB_27405468_Chip-Seq_BRAIN_Mouse1.63336837
42BCAT_22108803_ChIP-Seq_LS180_Human1.60720230
43ZNF274_21170338_ChIP-Seq_K562_Hela1.60479280
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.60277432
45IRF1_19129219_ChIP-ChIP_H3396_Human1.59299501
46EED_16625203_ChIP-ChIP_MESCs_Mouse1.57216807
47RNF2_27304074_Chip-Seq_NSC_Mouse1.56223902
48* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.54892742
49EST1_17652178_ChIP-ChIP_JURKAT_Human1.53709750
50GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51643174
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.47867632
52RBPJ_22232070_ChIP-Seq_NCS_Mouse1.47773567
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47466685
54MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45890416
55ER_23166858_ChIP-Seq_MCF-7_Human1.43757190
56SMAD4_21799915_ChIP-Seq_A2780_Human1.43106409
57GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42576208
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.41178314
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40896801
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40306736
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39976624
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.39906394
63ELF1_17652178_ChIP-ChIP_JURKAT_Human1.38391983
64PCGF2_27294783_Chip-Seq_NPCs_Mouse1.38251230
65HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.37090967
66* VDR_23849224_ChIP-Seq_CD4+_Human1.36574289
67NOTCH1_21737748_ChIP-Seq_TLL_Human1.34544158
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.33034810
69NFE2_27457419_Chip-Seq_LIVER_Mouse1.28449261
70GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28322737
71EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.27863360
72DROSHA_22980978_ChIP-Seq_HELA_Human1.26849672
73HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.26778765
74NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26758914
75EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26713534
76ELK1_19687146_ChIP-ChIP_HELA_Human1.25012963
77CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.24207665
78KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.23732745
79TP53_22573176_ChIP-Seq_HFKS_Human1.22585966
80PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.22025290
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21193268
82TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20430186
83AR_25329375_ChIP-Seq_VCAP_Human1.20288019
84SMAD3_21741376_ChIP-Seq_EPCs_Human1.19299548
85VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18584856
86POU5F1_16153702_ChIP-ChIP_HESCs_Human1.17853368
87SOX2_19829295_ChIP-Seq_ESCs_Human1.17262565
88NANOG_19829295_ChIP-Seq_ESCs_Human1.17262565
89KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16860191
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16022350
91EWS_26573619_Chip-Seq_HEK293_Human1.15656925
92P53_22387025_ChIP-Seq_ESCs_Mouse1.15471262
93SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14809776
94REST_19997604_ChIP-ChIP_NEURONS_Mouse1.14162549
95IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13314751
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.12079711
97FOXA1_21572438_ChIP-Seq_LNCaP_Human1.11967050
98NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.11815367
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.10279848
100CRX_20693478_ChIP-Seq_RETINA_Mouse1.09345889
101FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.08708789
102CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07652875
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05862982
104MYC_18940864_ChIP-ChIP_HL60_Human1.05143968
105* TCF4_22108803_ChIP-Seq_LS180_Human1.03407532
106RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.03121357
107RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.02464762
108SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.01975647
109MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01667578
110CMYC_18555785_Chip-Seq_ESCs_Mouse1.01391383
111IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01159913
112CBP_20019798_ChIP-Seq_JUKART_Human1.01159913
113FOXA1_27270436_Chip-Seq_PROSTATE_Human0.99815642
114FOXA1_25329375_ChIP-Seq_VCAP_Human0.99815642
115PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99690597
116SCL_19346495_ChIP-Seq_HPC-7_Human0.98813729
117OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97963408
118JUN_21703547_ChIP-Seq_K562_Human0.97238844
119ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.97224393
120SMAD_19615063_ChIP-ChIP_OVARY_Human0.97129174
121E2F1_18555785_Chip-Seq_ESCs_Mouse0.96957606
122NANOG_18555785_Chip-Seq_ESCs_Mouse0.96397243
123STAT3_18555785_Chip-Seq_ESCs_Mouse0.96110110
124SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.95075177
125TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.94744413
126TP53_18474530_ChIP-ChIP_U2OS_Human0.94255454
127RING1B_27294783_Chip-Seq_ESCs_Mouse0.93953667
128P53_22127205_ChIP-Seq_FIBROBLAST_Human0.93864799
129LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.93134365
130KDM2B_26808549_Chip-Seq_REH_Human0.93068464
131TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91689671
132RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.91330078
133NR3C1_23031785_ChIP-Seq_PC12_Mouse0.90951730
134E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.90568216
135CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89543558
136SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.88481859
137SOX2_21211035_ChIP-Seq_LN229_Gbm0.85191660
138TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85034850
139POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.85034850
140* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84977795
141STAT3_23295773_ChIP-Seq_U87_Human0.83857327
142ETV2_25802403_ChIP-Seq_MESCs_Mouse0.83721212
143ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82335004
144MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.82296767
145RUNX2_22187159_ChIP-Seq_PCA_Human0.81497690
146FLI1_21867929_ChIP-Seq_TH2_Mouse0.80897183
147SOX9_26525672_Chip-Seq_HEART_Mouse0.80565301
148DNAJC2_21179169_ChIP-ChIP_NT2_Human0.79882712
149* TCF4_23295773_ChIP-Seq_U87_Human0.79738962

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.31035544
2MP0009379_abnormal_foot_pigmentation4.28664164
3MP0004859_abnormal_synaptic_plasticity4.10044135
4MP0004270_analgesia3.34876686
5MP0003635_abnormal_synaptic_transmissio3.18943834
6MP0001188_hyperpigmentation3.06082463
7MP0003122_maternal_imprinting2.86086627
8MP0009745_abnormal_behavioral_response2.62285083
9MP0001529_abnormal_vocalization2.60807660
10MP0002063_abnormal_learning/memory/cond2.50074046
11MP0001968_abnormal_touch/_nociception2.44857163
12MP0002064_seizures2.34291776
13MP0002572_abnormal_emotion/affect_behav2.24477985
14MP0002736_abnormal_nociception_after2.20354899
15MP0002735_abnormal_chemical_nociception2.18929482
16MP0003121_genomic_imprinting2.18925693
17MP0004133_heterotaxia2.16589355
18MP0002734_abnormal_mechanical_nocicepti2.12081880
19MP0006276_abnormal_autonomic_nervous2.11397148
20MP0002272_abnormal_nervous_system2.09238161
21MP0001984_abnormal_olfaction2.05170490
22MP0005423_abnormal_somatic_nervous2.01576176
23MP0001486_abnormal_startle_reflex1.91373760
24MP0005084_abnormal_gallbladder_morpholo1.90845584
25MP0002733_abnormal_thermal_nociception1.90615196
26MP0003329_amyloid_beta_deposits1.89270451
27MP0005171_absent_coat_pigmentation1.85182359
28MP0000778_abnormal_nervous_system1.84419944
29MP0006292_abnormal_olfactory_placode1.76705074
30MP0001905_abnormal_dopamine_level1.74714585
31MP0001970_abnormal_pain_threshold1.73722979
32MP0002067_abnormal_sensory_capabilities1.73631259
33MP0001440_abnormal_grooming_behavior1.71364767
34MP0005645_abnormal_hypothalamus_physiol1.70100101
35MP0000015_abnormal_ear_pigmentation1.69935086
36MP0009046_muscle_twitch1.68527532
37MP0005253_abnormal_eye_physiology1.68285548
38MP0003303_peritoneal_inflammation1.67892416
39MP0005409_darkened_coat_color1.63085935
40MP0002928_abnormal_bile_duct1.62211734
41MP0002184_abnormal_innervation1.62029220
42MP0002557_abnormal_social/conspecific_i1.55078006
43MP0005386_behavior/neurological_phenoty1.53047493
44MP0004924_abnormal_behavior1.53047493
45MP0000372_irregular_coat_pigmentation1.45314599
46MP0003787_abnormal_imprinting1.43107036
47MP0004811_abnormal_neuron_physiology1.38466037
48MP0000955_abnormal_spinal_cord1.37862790
49MP0005499_abnormal_olfactory_system1.37484504
50MP0005394_taste/olfaction_phenotype1.37484504
51MP0005367_renal/urinary_system_phenotyp1.37412799
52MP0000516_abnormal_urinary_system1.37412799
53MP0001919_abnormal_reproductive_system1.37369656
54MP0005174_abnormal_tail_pigmentation1.31346691
55MP0001502_abnormal_circadian_rhythm1.30100764
56MP0005646_abnormal_pituitary_gland1.29740444
57MP0008789_abnormal_olfactory_epithelium1.29730519
58MP0003879_abnormal_hair_cell1.28013782
59MP0002234_abnormal_pharynx_morphology1.27834757
60MP0008569_lethality_at_weaning1.26251172
61MP0001324_abnormal_eye_pigmentation1.26017561
62MP0002102_abnormal_ear_morphology1.25907125
63MP0002638_abnormal_pupillary_reflex1.24918726
64MP0004142_abnormal_muscle_tone1.24305387
65MP0006072_abnormal_retinal_apoptosis1.22513014
66MP0002882_abnormal_neuron_morphology1.22419048
67MP0003890_abnormal_embryonic-extraembry1.22271557
68MP0004742_abnormal_vestibular_system1.20878488
69MP0001986_abnormal_taste_sensitivity1.20638223
70MP0002277_abnormal_respiratory_mucosa1.20320745
71MP0002095_abnormal_skin_pigmentation1.18458450
72MP0001501_abnormal_sleep_pattern1.17421272
73MP0010386_abnormal_urinary_bladder1.16354061
74MP0005187_abnormal_penis_morphology1.14988219
75MP0005551_abnormal_eye_electrophysiolog1.14724651
76MP0002066_abnormal_motor_capabilities/c1.13349319
77MP0008058_abnormal_DNA_repair1.12534794
78MP0000566_synostosis1.12071220
79MP0000631_abnormal_neuroendocrine_gland1.11977178
80MP0000465_gastrointestinal_hemorrhage1.10966728
81MP0003633_abnormal_nervous_system1.10502899
82MP0001764_abnormal_homeostasis1.09922442
83MP0008995_early_reproductive_senescence1.08253145
84MP0008875_abnormal_xenobiotic_pharmacok1.04380630
85MP0000569_abnormal_digit_pigmentation1.03246973
86MP0005195_abnormal_posterior_eye1.02918002
87MP0003868_abnormal_feces_composition1.02271434
88MP0002233_abnormal_nose_morphology0.99630517
89MP0000920_abnormal_myelination0.99165160
90MP0002229_neurodegeneration0.98941106
91MP0002938_white_spotting0.98819736
92MP0001485_abnormal_pinna_reflex0.98591997
93MP0003136_yellow_coat_color0.98428658
94MP0000013_abnormal_adipose_tissue0.97646572
95MP0004147_increased_porphyrin_level0.96726736
96MP0002152_abnormal_brain_morphology0.95370250
97MP0002837_dystrophic_cardiac_calcinosis0.94821477
98MP0005075_abnormal_melanosome_morpholog0.94336552
99MP0001270_distended_abdomen0.93819194
100MP0003011_delayed_dark_adaptation0.93628290
101MP0005671_abnormal_response_to0.93587659
102MP0003195_calcinosis0.91560189
103MP0003631_nervous_system_phenotype0.91216322
104MP0000639_abnormal_adrenal_gland0.91090832
105MP0003252_abnormal_bile_duct0.91014746
106MP0005389_reproductive_system_phenotype0.89393486
107MP0004043_abnormal_pH_regulation0.89280343
108MP0005391_vision/eye_phenotype0.86896260
109MP0002909_abnormal_adrenal_gland0.85428254
110MP0008872_abnormal_physiological_respon0.84008297
111MP0008877_abnormal_DNA_methylation0.83529526
112MP0002752_abnormal_somatic_nervous0.83322425
113MP0001293_anophthalmia0.82888617
114MP0006035_abnormal_mitochondrial_morpho0.82368955
115MP0003724_increased_susceptibility_to0.82012505
116MP0000026_abnormal_inner_ear0.81750799
117MP0002876_abnormal_thyroid_physiology0.80190800
118MP0002822_catalepsy0.79740540
119MP0001963_abnormal_hearing_physiology0.79032980
120MP0002751_abnormal_autonomic_nervous0.78056716
121MP0003119_abnormal_digestive_system0.77369888
122MP0002282_abnormal_trachea_morphology0.76499608
123MP0000647_abnormal_sebaceous_gland0.76200971
124MP0003656_abnormal_erythrocyte_physiolo0.75174809
125MP0000427_abnormal_hair_cycle0.74854546
126MP0001929_abnormal_gametogenesis0.74482320
127MP0004885_abnormal_endolymph0.74143254
128MP0003183_abnormal_peptide_metabolism0.72978084
129MP0001664_abnormal_digestion0.71659074
130MP0002069_abnormal_eating/drinking_beha0.70117101
131MP0005248_abnormal_Harderian_gland0.69307953
132MP0004858_abnormal_nervous_system0.69208196
133MP0003634_abnormal_glial_cell0.68968060
134MP0005410_abnormal_fertilization0.66225003
135MP0008874_decreased_physiological_sensi0.64626928
136MP0004130_abnormal_muscle_cell0.64532808
137MP0000604_amyloidosis0.62762534
138MP0002653_abnormal_ependyma_morphology0.62650585
139MP0000462_abnormal_digestive_system0.62085516
140MP0003698_abnormal_male_reproductive0.62038519
141MP0003646_muscle_fatigue0.61948319
142MP0001663_abnormal_digestive_system0.60948057

Predicted human phenotypes

RankGene SetZ-score
1Retinal dysplasia (HP:0007973)5.67909175
2Type II lissencephaly (HP:0007260)5.44160057
3Cerebellar dysplasia (HP:0007033)4.52890911
4True hermaphroditism (HP:0010459)3.99578680
5Genital tract atresia (HP:0001827)3.97075286
6Pancreatic cysts (HP:0001737)3.94976514
7Focal motor seizures (HP:0011153)3.82616394
8Hepatoblastoma (HP:0002884)3.82601745
9Vaginal atresia (HP:0000148)3.77590921
10Ankle clonus (HP:0011448)3.60639977
11Inability to walk (HP:0002540)3.59373486
12Myokymia (HP:0002411)3.57938515
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.50538753
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.50538753
15Retinal atrophy (HP:0001105)3.48994809
16Neoplasm of the adrenal cortex (HP:0100641)3.41100507
17Molar tooth sign on MRI (HP:0002419)3.37192304
18Abnormality of midbrain morphology (HP:0002418)3.37192304
19Visual hallucinations (HP:0002367)3.34540501
20Lissencephaly (HP:0001339)3.30379307
21Colon cancer (HP:0003003)3.30112471
22Absent speech (HP:0001344)3.22413917
23Chronic hepatic failure (HP:0100626)3.21937538
24Epileptic encephalopathy (HP:0200134)3.18513114
25Poor coordination (HP:0002370)3.11787727
26Progressive inability to walk (HP:0002505)3.06325910
27Nephronophthisis (HP:0000090)2.95745122
28Anterior segment dysgenesis (HP:0007700)2.94022339
29Atonic seizures (HP:0010819)2.87008438
30Severe visual impairment (HP:0001141)2.85524962
31Acute necrotizing encephalopathy (HP:0006965)2.79876362
32Aplasia/Hypoplasia of the brainstem (HP:0007362)2.79797558
33Hypoplasia of the brainstem (HP:0002365)2.79797558
34Short tibia (HP:0005736)2.79689313
35Broad foot (HP:0001769)2.76416618
36Focal seizures (HP:0007359)2.75607888
37Supranuclear gaze palsy (HP:0000605)2.75248281
38Abnormal mitochondria in muscle tissue (HP:0008316)2.71444561
39Limb dystonia (HP:0002451)2.69164850
40Aplasia/Hypoplasia of the tibia (HP:0005772)2.68982362
41Aplasia/Hypoplasia of the tongue (HP:0010295)2.65101151
42Ragged-red muscle fibers (HP:0003200)2.64642258
43Mitochondrial inheritance (HP:0001427)2.64115531
44Polyphagia (HP:0002591)2.62584428
45Thyroiditis (HP:0100646)2.61323545
46Progressive cerebellar ataxia (HP:0002073)2.60004265
47Absence seizures (HP:0002121)2.56118313
48Gait imbalance (HP:0002141)2.55222864
49Buphthalmos (HP:0000557)2.54292535
50Specific learning disability (HP:0001328)2.52399093
51Scanning speech (HP:0002168)2.51654750
52Progressive macrocephaly (HP:0004481)2.48409301
53Postaxial hand polydactyly (HP:0001162)2.48273108
54Dialeptic seizures (HP:0011146)2.46225427
55Severe combined immunodeficiency (HP:0004430)2.44952097
56Amyotrophic lateral sclerosis (HP:0007354)2.43323238
57Severe muscular hypotonia (HP:0006829)2.42056880
58Abnormality of the renal medulla (HP:0100957)2.41550608
59Pachygyria (HP:0001302)2.41547527
60Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.39838454
61Degeneration of the lateral corticospinal tracts (HP:0002314)2.39838454
62Anencephaly (HP:0002323)2.39105254
63Occipital encephalocele (HP:0002085)2.38013913
64Neurofibrillary tangles (HP:0002185)2.37865311
65Renal Fanconi syndrome (HP:0001994)2.35370742
66Mutism (HP:0002300)2.35085208
67Increased hepatocellular lipid droplets (HP:0006565)2.34672663
68Abnormality of the labia minora (HP:0012880)2.33687922
69Tented upper lip vermilion (HP:0010804)2.32310646
70Abnormality of the corticospinal tract (HP:0002492)2.31712562
71Abolished electroretinogram (ERG) (HP:0000550)2.29059350
72Anxiety (HP:0000739)2.27887266
733-Methylglutaconic aciduria (HP:0003535)2.27814436
74Neoplasm of the adrenal gland (HP:0100631)2.26360285
75Broad-based gait (HP:0002136)2.24940984
76Hyperglycinemia (HP:0002154)2.24782495
77Febrile seizures (HP:0002373)2.24481616
78Methylmalonic acidemia (HP:0002912)2.24435134
79Poor suck (HP:0002033)2.20658390
80Spastic gait (HP:0002064)2.20539582
81Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.20412325
82Cystic liver disease (HP:0006706)2.18657317
83Hepatocellular necrosis (HP:0001404)2.17356456
84Aplasia/Hypoplasia of the lens (HP:0008063)2.17195813
85Medial flaring of the eyebrow (HP:0010747)2.16759805
86Increased intramyocellular lipid droplets (HP:0012240)2.15074541
87Hypothermia (HP:0002045)2.14412909
88Truncal ataxia (HP:0002078)2.12203907
89Bile duct proliferation (HP:0001408)2.11520765
90Abnormal biliary tract physiology (HP:0012439)2.11520765
91Agitation (HP:0000713)2.09969790
92Lipid accumulation in hepatocytes (HP:0006561)2.09323227
93Increased CSF lactate (HP:0002490)2.08690069
94Postaxial foot polydactyly (HP:0001830)2.08136068
95Attenuation of retinal blood vessels (HP:0007843)2.06136256
96Decreased testicular size (HP:0008734)2.05510634
97Synostosis involving the elbow (HP:0003938)2.04448326
98Humeroradial synostosis (HP:0003041)2.04448326
99Congenital stationary night blindness (HP:0007642)2.04082611
100Failure to thrive in infancy (HP:0001531)2.03781399
101Cerebral inclusion bodies (HP:0100314)2.03658740
102Abnormal hair whorl (HP:0010721)2.03011665
103Male pseudohermaphroditism (HP:0000037)2.02341677
104Retinitis pigmentosa (HP:0000510)2.02111609
105Amblyopia (HP:0000646)2.01873979
106Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.00527529
107Hemiparesis (HP:0001269)2.00109765
108Abnormal ciliary motility (HP:0012262)2.00014445
109Sclerocornea (HP:0000647)1.98791288
110Nemaline bodies (HP:0003798)1.98291309
111Supernumerary spleens (HP:0009799)1.97390232
112Metaphyseal dysplasia (HP:0100255)1.96940669
113Abnormal respiratory epithelium morphology (HP:0012253)1.96604095
114Abnormal respiratory motile cilium morphology (HP:0005938)1.96604095
115Abnormality of the renal cortex (HP:0011035)1.95939384
116Abnormal respiratory motile cilium physiology (HP:0012261)1.95440681
117Congenital primary aphakia (HP:0007707)1.95267436
118Congenital glaucoma (HP:0001087)1.95232595
119Epileptiform EEG discharges (HP:0011182)1.95089275
120Thyroid-stimulating hormone excess (HP:0002925)1.94984624
121EEG with generalized epileptiform discharges (HP:0011198)1.94555850
122Macroglossia (HP:0000158)1.94194290
123Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.94064928
124Acute encephalopathy (HP:0006846)1.92031560
125Atrophy/Degeneration involving motor neurons (HP:0007373)1.91953339
126Papillary thyroid carcinoma (HP:0002895)1.91925260
127Nephrogenic diabetes insipidus (HP:0009806)1.90691126
128Depression (HP:0000716)1.88995543
129Esotropia (HP:0000565)1.88772687
130Non-midline cleft lip (HP:0100335)1.87914177
131Nephrotic syndrome (HP:0000100)1.87421682
132Type I transferrin isoform profile (HP:0003642)1.87122677
133Meningocele (HP:0002435)1.86824886
134Hyperventilation (HP:0002883)1.86564653
135Asthma (HP:0002099)1.86475658
136Fetal akinesia sequence (HP:0001989)1.86348121
137Rhinitis (HP:0012384)1.84240105
138Broad alveolar ridges (HP:0000187)1.83810954
139Abnormality of macular pigmentation (HP:0008002)1.83392881
140IgG deficiency (HP:0004315)1.83102326
141Drooling (HP:0002307)1.82519482
142Excessive salivation (HP:0003781)1.82519482
143Pancreatic fibrosis (HP:0100732)1.81917756
144Short foot (HP:0001773)1.80924685
145Megalencephaly (HP:0001355)1.79512756
146Bradykinesia (HP:0002067)1.79333214
147Decreased central vision (HP:0007663)1.78948106
148Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.78836961
149Stomatitis (HP:0010280)1.78786631
150Renal cortical cysts (HP:0000803)1.78034337
151Pheochromocytoma (HP:0002666)1.77831231
152Abnormality of the heme biosynthetic pathway (HP:0010472)1.76360761
153Stomach cancer (HP:0012126)1.76339272
154Narrow forehead (HP:0000341)1.75645773
155Concave nail (HP:0001598)1.75469927
156Methylmalonic aciduria (HP:0012120)1.74131444
157Morphological abnormality of the pyramidal tract (HP:0002062)1.73495510
158Thyroid carcinoma (HP:0002890)1.72025665
159Poor eye contact (HP:0000817)1.71501439
160Urinary urgency (HP:0000012)1.71447887
161Neuroendocrine neoplasm (HP:0100634)1.71287772
162Lower limb muscle weakness (HP:0007340)1.70182691
163Multicystic kidney dysplasia (HP:0000003)1.70051945
164Congenital hepatic fibrosis (HP:0002612)1.69727135
165Muscular hypotonia of the trunk (HP:0008936)1.69521655
166Abnormal eating behavior (HP:0100738)1.69417403
167Abnormality of binocular vision (HP:0011514)1.69066307
168Diplopia (HP:0000651)1.69066307
169Hip dysplasia (HP:0001385)1.69061729
170Left ventricular hypertrophy (HP:0001712)1.68390753
171Astigmatism (HP:0000483)1.67356463
172Exertional dyspnea (HP:0002875)1.64300501

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.67170198
2MAP3K123.85950787
3TAOK33.06909618
4MAP2K72.85391171
5MAP4K22.79966778
6TNIK2.79884634
7CSNK1G32.77168218
8WNK32.65033142
9CSNK1G22.51173328
10PNCK2.47539064
11NUAK12.35458740
12FRK2.35228724
13EPHA42.28396193
14CSNK1A1L2.26062455
15TRIM282.23378117
16CASK2.14310332
17ACVR1B2.14195541
18MAPK132.10297804
19FES2.08631884
20MINK12.03314140
21MAP3K91.94420191
22CSNK1G11.94046658
23DYRK21.93417620
24CDK191.92916261
25NTRK31.88829110
26BCKDK1.85641382
27MAP3K41.79379100
28MAP3K61.77227920
29CAMKK21.75064948
30NTRK21.72960126
31ADRBK21.68355634
32DAPK21.64007479
33KSR11.63486027
34MAPK151.62168723
35SCYL21.59181036
36KSR21.50823860
37MUSK1.49301496
38RAF11.48031995
39EPHA31.45386747
40ZAK1.43321022
41ARAF1.39592374
42RPS6KA41.38115480
43SRPK11.35674267
44NME11.34635211
45SIK21.33503696
46MAP2K41.23127019
47DAPK11.22536820
48PHKG11.22457058
49PHKG21.22457058
50WNK41.17071166
51ERBB31.16481579
52GRK11.16444343
53FGFR21.16321918
54MAPKAPK51.15400538
55PAK61.14875188
56DYRK1A1.13477177
57BRD41.11131653
58TLK11.08475175
59STK161.04662812
60CAMK11.04292898
61MARK21.03538718
62RPS6KA51.01756341
63RIPK41.00349216
64TXK0.99020572
65DYRK30.97242642
66PINK10.96698125
67DYRK1B0.96674021
68CDK50.96586053
69FLT30.89844173
70PLK20.87832773
71UHMK10.86183944
72PASK0.86182241
73GRK50.85438530
74STK390.85389792
75KIT0.85031688
76LIMK10.84155840
77CAMKK10.84057027
78MAP3K20.81247605
79CAMK2B0.76953230
80PRPF4B0.76771504
81CAMK2A0.74351297
82TEC0.72692897
83MKNK10.71842781
84GRK70.71430717
85MAP2K60.70507905
86IRAK10.65500847
87MAP4K10.64580201
88INSRR0.63873819
89IKBKE0.62859625
90EIF2AK10.62055535
91ITK0.61782332
92PRKCG0.59723084
93CAMK2G0.59124040
94YES10.59032053
95LMTK20.58801209
96NTRK10.57258951
97CAMK2D0.57222530
98BMPR1B0.56939117
99PAK30.56894984
100VRK10.56459848
101TGFBR10.56292664
102MAP3K130.56159757
103CDK140.55602744
104SYK0.55060409
105MAP3K10.54441590
106MAP3K50.54000670
107ADRBK10.51570376
108MAPK40.51154554
109TNK20.50112942
110CDK11A0.47181341
111BCR0.46314056
112CSF1R0.45884175
113OXSR10.45585774
114CDK180.44899584
115PIM10.44074113
116PRKACA0.43812507
117CDK150.43337592
118LYN0.41797191
119NLK0.41670810
120CAMK1G0.41485621
121STK38L0.41469052
122MYLK0.41123271
123PRKCZ0.40269658
124HIPK20.40227516
125ABL10.39941876
126FER0.39644052
127BRSK20.39322588
128ILK0.39162107
129EIF2AK30.38097901
130MAPK120.37631686
131PRKACB0.36544439
132IRAK20.36027363
133TYRO30.36017143
134ROCK20.35763665
135RET0.35131968
136TESK20.35008033
137LCK0.34779339
138EGFR0.34749480
139CDK30.33958432
140PRKCE0.33279272
141PRKCQ0.32364482
142MAP3K70.32134046
143GRK60.31028930
144PRKD30.30987430
145PIM20.30662338
146CCNB10.30238996
147IKBKB0.28800215
148SIK30.27898606
149MARK30.26982425

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.74524860
2Nicotine addiction_Homo sapiens_hsa050333.09840499
3Regulation of autophagy_Homo sapiens_hsa041402.93101808
4Butanoate metabolism_Homo sapiens_hsa006502.64004499
5Synaptic vesicle cycle_Homo sapiens_hsa047212.62432054
6Circadian entrainment_Homo sapiens_hsa047132.49744094
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.48947647
8Oxidative phosphorylation_Homo sapiens_hsa001902.43591663
9Glutamatergic synapse_Homo sapiens_hsa047242.42410807
10Other types of O-glycan biosynthesis_Homo sapiens_hsa005142.32055839
11Parkinsons disease_Homo sapiens_hsa050122.19386975
12GABAergic synapse_Homo sapiens_hsa047272.19297883
13Sulfur metabolism_Homo sapiens_hsa009202.18179859
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.08200252
15Long-term potentiation_Homo sapiens_hsa047202.04717513
16Alzheimers disease_Homo sapiens_hsa050102.01792329
17Dopaminergic synapse_Homo sapiens_hsa047281.97726821
18Morphine addiction_Homo sapiens_hsa050321.96881884
19Serotonergic synapse_Homo sapiens_hsa047261.95962814
20Long-term depression_Homo sapiens_hsa047301.94687778
21Olfactory transduction_Homo sapiens_hsa047401.80198101
22Linoleic acid metabolism_Homo sapiens_hsa005911.72374879
23Cholinergic synapse_Homo sapiens_hsa047251.70241436
24Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.69826675
25SNARE interactions in vesicular transport_Homo sapiens_hsa041301.68738727
26Protein export_Homo sapiens_hsa030601.65921205
27Renin secretion_Homo sapiens_hsa049241.64799918
28Amphetamine addiction_Homo sapiens_hsa050311.62727816
29Huntingtons disease_Homo sapiens_hsa050161.61917704
30Peroxisome_Homo sapiens_hsa041461.60751682
31Salivary secretion_Homo sapiens_hsa049701.60696183
32Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.60273765
33alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.58545644
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.55079892
35Ribosome_Homo sapiens_hsa030101.53472872
36Cocaine addiction_Homo sapiens_hsa050301.52227598
37Insulin secretion_Homo sapiens_hsa049111.49650873
38Selenocompound metabolism_Homo sapiens_hsa004501.49429754
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48239038
40Taste transduction_Homo sapiens_hsa047421.48231992
41Cardiac muscle contraction_Homo sapiens_hsa042601.47123099
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.46945924
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.46714274
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.46452933
45Nitrogen metabolism_Homo sapiens_hsa009101.45990149
46Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.45222909
47Fanconi anemia pathway_Homo sapiens_hsa034601.44664900
48Collecting duct acid secretion_Homo sapiens_hsa049661.44653747
49Vibrio cholerae infection_Homo sapiens_hsa051101.41755240
50Basal transcription factors_Homo sapiens_hsa030221.39885782
51Caffeine metabolism_Homo sapiens_hsa002321.38644345
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.32836682
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.32243949
54Oxytocin signaling pathway_Homo sapiens_hsa049211.29850092
55Gap junction_Homo sapiens_hsa045401.27413551
56Propanoate metabolism_Homo sapiens_hsa006401.26691321
57Fatty acid elongation_Homo sapiens_hsa000621.23624113
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.16856581
59Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16006474
60Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.10788468
61Gastric acid secretion_Homo sapiens_hsa049711.10066476
62Axon guidance_Homo sapiens_hsa043601.06503757
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.02854562
64Calcium signaling pathway_Homo sapiens_hsa040201.00762995
65GnRH signaling pathway_Homo sapiens_hsa049120.98844377
66Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.97156640
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.96239137
68Chemical carcinogenesis_Homo sapiens_hsa052040.95970399
69Alcoholism_Homo sapiens_hsa050340.93044388
70Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.92166027
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.91527226
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.91359843
73Colorectal cancer_Homo sapiens_hsa052100.89596577
74cAMP signaling pathway_Homo sapiens_hsa040240.89528166
75N-Glycan biosynthesis_Homo sapiens_hsa005100.88826312
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88302203
77Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.87266214
78Type I diabetes mellitus_Homo sapiens_hsa049400.86488169
79Nucleotide excision repair_Homo sapiens_hsa034200.85086295
80Retinol metabolism_Homo sapiens_hsa008300.80681452
81Steroid biosynthesis_Homo sapiens_hsa001000.78852145
82RNA polymerase_Homo sapiens_hsa030200.76761319
83Phototransduction_Homo sapiens_hsa047440.76550390
84Endometrial cancer_Homo sapiens_hsa052130.75864538
85Tryptophan metabolism_Homo sapiens_hsa003800.73655673
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72958786
87Estrogen signaling pathway_Homo sapiens_hsa049150.72387569
88Non-homologous end-joining_Homo sapiens_hsa034500.71477546
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71294800
90Oocyte meiosis_Homo sapiens_hsa041140.71114255
91ABC transporters_Homo sapiens_hsa020100.70981115
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.70601018
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.69644312
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68618982
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.66769057
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66032172
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65147730
98Hedgehog signaling pathway_Homo sapiens_hsa043400.63930846
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.62281923
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.60189498
101Vascular smooth muscle contraction_Homo sapiens_hsa042700.59293813
102p53 signaling pathway_Homo sapiens_hsa041150.58488079
103cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57635818
104ErbB signaling pathway_Homo sapiens_hsa040120.56643186
105Arachidonic acid metabolism_Homo sapiens_hsa005900.56183459
106Purine metabolism_Homo sapiens_hsa002300.55496547
107Melanogenesis_Homo sapiens_hsa049160.55170946
108Primary immunodeficiency_Homo sapiens_hsa053400.53411111
109T cell receptor signaling pathway_Homo sapiens_hsa046600.50744308
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50685623
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50337803
112VEGF signaling pathway_Homo sapiens_hsa043700.49987179
113Platelet activation_Homo sapiens_hsa046110.49738905
114Intestinal immune network for IgA production_Homo sapiens_hsa046720.49697308
115Rheumatoid arthritis_Homo sapiens_hsa053230.48569025
116Glioma_Homo sapiens_hsa052140.48260029
117Circadian rhythm_Homo sapiens_hsa047100.47296185
118Choline metabolism in cancer_Homo sapiens_hsa052310.46663653
119Pancreatic secretion_Homo sapiens_hsa049720.46176413
120RNA degradation_Homo sapiens_hsa030180.45870985
121Mineral absorption_Homo sapiens_hsa049780.45789244
122Metabolic pathways_Homo sapiens_hsa011000.45532664
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.45032035
124Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43199907
125MAPK signaling pathway_Homo sapiens_hsa040100.42575556
126Glycerophospholipid metabolism_Homo sapiens_hsa005640.41825636
127Ras signaling pathway_Homo sapiens_hsa040140.41466435
128Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41182104
129Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.39454141
130Ether lipid metabolism_Homo sapiens_hsa005650.39256501
131beta-Alanine metabolism_Homo sapiens_hsa004100.38957957
132Folate biosynthesis_Homo sapiens_hsa007900.38791297
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38738741
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37908737
135Hematopoietic cell lineage_Homo sapiens_hsa046400.37766722
136Phosphatidylinositol signaling system_Homo sapiens_hsa040700.37521003
137Pyrimidine metabolism_Homo sapiens_hsa002400.37054488
138Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36802210
139Glycerolipid metabolism_Homo sapiens_hsa005610.35723966
140Base excision repair_Homo sapiens_hsa034100.35649906
141Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.35535220
142Renal cell carcinoma_Homo sapiens_hsa052110.35445848
143Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.35213471
144B cell receptor signaling pathway_Homo sapiens_hsa046620.33992934
145Fatty acid metabolism_Homo sapiens_hsa012120.33819003
146Shigellosis_Homo sapiens_hsa051310.32958319
147Thyroid hormone synthesis_Homo sapiens_hsa049180.32605102
148Proteasome_Homo sapiens_hsa030500.32300490
149Transcriptional misregulation in cancer_Homo sapiens_hsa052020.31519687
150Wnt signaling pathway_Homo sapiens_hsa043100.31334778
151Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.31030405
152Endocytosis_Homo sapiens_hsa041440.30270050
153Homologous recombination_Homo sapiens_hsa034400.29076196
154Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28858705
155Legionellosis_Homo sapiens_hsa051340.25568220
156Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.24147807
157Spliceosome_Homo sapiens_hsa030400.23741291
158NOD-like receptor signaling pathway_Homo sapiens_hsa046210.21368159

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