ANKRD13C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.25981815
2aminoglycoside antibiotic metabolic process (GO:0030647)5.24763903
3negative regulation of dendrite morphogenesis (GO:0050774)5.13033096
4urate metabolic process (GO:0046415)4.73570846
5nuclear pore organization (GO:0006999)4.70451502
6presynaptic membrane assembly (GO:0097105)4.43266726
7dopamine biosynthetic process (GO:0042416)4.39635572
8cornea development in camera-type eye (GO:0061303)4.28807216
9negative regulation of keratinocyte proliferation (GO:0010839)4.28515903
10neuron cell-cell adhesion (GO:0007158)4.12959344
11pore complex assembly (GO:0046931)4.05658098
12ER overload response (GO:0006983)4.04015915
13drug transmembrane transport (GO:0006855)3.94823051
14regulation of development, heterochronic (GO:0040034)3.90427329
15ribonucleoprotein complex disassembly (GO:0032988)3.76020274
16glycoside metabolic process (GO:0016137)3.73672198
17regulation of synaptic vesicle exocytosis (GO:2000300)3.61012289
18polyol catabolic process (GO:0046174)3.59695455
19glutamate secretion (GO:0014047)3.57352111
20transferrin transport (GO:0033572)3.46700066
21presynaptic membrane organization (GO:0097090)3.44427180
22trivalent inorganic cation transport (GO:0072512)3.41735620
23ferric iron transport (GO:0015682)3.41735620
24mitotic sister chromatid cohesion (GO:0007064)3.40113296
25regulation of timing of cell differentiation (GO:0048505)3.37744779
26neural tube formation (GO:0001841)3.36340274
27postsynaptic membrane organization (GO:0001941)3.34252608
28startle response (GO:0001964)3.25473924
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.21509028
30organic cation transport (GO:0015695)3.20807235
31catechol-containing compound biosynthetic process (GO:0009713)3.20236504
32catecholamine biosynthetic process (GO:0042423)3.20236504
33pre-miRNA processing (GO:0031054)3.16976128
34monoubiquitinated protein deubiquitination (GO:0035520)3.16358245
35protein K11-linked deubiquitination (GO:0035871)3.12436671
36dorsal/ventral axis specification (GO:0009950)3.12365498
37ribosome assembly (GO:0042255)3.09305721
38phosphate ion transport (GO:0006817)3.09097016
39neurotransmitter-gated ion channel clustering (GO:0072578)3.04901843
40regulation of synaptic vesicle transport (GO:1902803)3.04673376
41response to insecticide (GO:0017085)3.04427825
42vocalization behavior (GO:0071625)3.04050228
43negative regulation of dendrite development (GO:2000171)3.02923314
44mechanosensory behavior (GO:0007638)2.99127680
45positive regulation of mitochondrial fission (GO:0090141)2.97791258
46gastrulation with mouth forming second (GO:0001702)2.93717345
47positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.93589803
48mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.93589803
49establishment of integrated proviral latency (GO:0075713)2.92889433
50auditory behavior (GO:0031223)2.92461406
51regulation of cAMP-dependent protein kinase activity (GO:2000479)2.92459299
52positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.89255392
53synaptic vesicle exocytosis (GO:0016079)2.88335747
54negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.87022702
55neurotransmitter biosynthetic process (GO:0042136)2.86945933
56cytoplasmic mRNA processing body assembly (GO:0033962)2.86358973
57positive regulation of neuroblast proliferation (GO:0002052)2.84602938
58membrane assembly (GO:0071709)2.83680284
59regulation of establishment of cell polarity (GO:2000114)2.82738529
60neurotransmitter secretion (GO:0007269)2.81216704
61regulation of RNA export from nucleus (GO:0046831)2.80740329
62negative regulation of synaptic transmission, GABAergic (GO:0032229)2.80512924
63negative regulation of hormone metabolic process (GO:0032351)2.79903225
64negative regulation of hormone biosynthetic process (GO:0032353)2.79903225
65response to pheromone (GO:0019236)2.78341718
66drug transport (GO:0015893)2.77486149
67protein targeting to Golgi (GO:0000042)2.77446364
68regulation of cell maturation (GO:1903429)2.76287858
69non-recombinational repair (GO:0000726)2.74844511
70double-strand break repair via nonhomologous end joining (GO:0006303)2.74844511
71spindle checkpoint (GO:0031577)2.73391176
72organelle disassembly (GO:1903008)2.72889569
73cellular response to ammonium ion (GO:0071242)2.71488835
74excretion (GO:0007588)2.71471239
75regulation of short-term neuronal synaptic plasticity (GO:0048172)2.71055278
76negative regulation of glycogen biosynthetic process (GO:0045719)2.69986377
77synaptic vesicle docking involved in exocytosis (GO:0016081)2.69063018
78establishment of protein localization to Golgi (GO:0072600)2.68689908
79positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.68052260
80mitotic spindle checkpoint (GO:0071174)2.67907746
81regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.67796371
82cellular response to gamma radiation (GO:0071480)2.67566859
83regulation of glucokinase activity (GO:0033131)2.64431663
84regulation of hexokinase activity (GO:1903299)2.64431663
85intraciliary transport (GO:0042073)2.64337907
86regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.63914942
87regulation of mitotic metaphase/anaphase transition (GO:0030071)2.63914942
88spindle assembly checkpoint (GO:0071173)2.63881948
89mitotic spindle assembly checkpoint (GO:0007094)2.63397675
90myelin assembly (GO:0032288)2.62806615
91negative regulation of sister chromatid segregation (GO:0033046)2.61734196
92negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.61734196
93negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.61734196
94negative regulation of mitotic sister chromatid segregation (GO:0033048)2.61734196
95negative regulation of mitotic sister chromatid separation (GO:2000816)2.61734196
96microtubule anchoring (GO:0034453)2.61423608
97regulation of mitotic sister chromatid separation (GO:0010965)2.60419923
98regulation of mitotic sister chromatid segregation (GO:0033047)2.60419923
99regulation of sister chromatid segregation (GO:0033045)2.60419923
100negative regulation of systemic arterial blood pressure (GO:0003085)2.59741351
101embryonic camera-type eye morphogenesis (GO:0048596)2.59392735
102DNA double-strand break processing (GO:0000729)2.58547076
103histone H2A ubiquitination (GO:0033522)2.58536342
104regulation of establishment or maintenance of cell polarity (GO:0032878)2.57600821
105regulation of centriole replication (GO:0046599)2.56009951
106positive regulation of cell fate commitment (GO:0010455)2.55864608
107histone H2A acetylation (GO:0043968)2.55683201
108glial cell proliferation (GO:0014009)2.55294756
109keratinocyte development (GO:0003334)2.55211492
110negative regulation of chromosome segregation (GO:0051985)2.53113630
111response to parathyroid hormone (GO:0071107)2.51688211
112phagosome maturation (GO:0090382)2.51507167
113COPII vesicle coating (GO:0048208)2.50098553
114histone H2A monoubiquitination (GO:0035518)2.50061077
115locomotory exploration behavior (GO:0035641)2.49502956
116protein prenylation (GO:0018342)2.47539938
117prenylation (GO:0097354)2.47539938
118negative regulation of neurotransmitter secretion (GO:0046929)2.47458289
119morphogenesis of an epithelial sheet (GO:0002011)2.46908149
120trivalent inorganic anion homeostasis (GO:0072506)2.46729156
121phosphate ion homeostasis (GO:0055062)2.46729156
122metaphase plate congression (GO:0051310)2.46055181
123oligosaccharide catabolic process (GO:0009313)2.45278063
124retrograde transport, vesicle recycling within Golgi (GO:0000301)2.44614168
125neuron-neuron synaptic transmission (GO:0007270)2.44568933
126renal absorption (GO:0070293)2.44444441
127olfactory bulb development (GO:0021772)2.44407193
128ether lipid metabolic process (GO:0046485)2.44117268
129dopamine metabolic process (GO:0042417)2.43639953
130proline transport (GO:0015824)2.43484362
131vitamin transmembrane transport (GO:0035461)2.43144226
132fibroblast migration (GO:0010761)2.43034348
133sister chromatid segregation (GO:0000819)2.42379194
134regulation of long-term neuronal synaptic plasticity (GO:0048169)2.41699174
135membrane repolarization during action potential (GO:0086011)2.41680011
136regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.41047713
137regulation of mitotic spindle checkpoint (GO:1903504)2.41047713
138secondary heart field specification (GO:0003139)2.40899865
139heart field specification (GO:0003128)2.40899865
140serotonin receptor signaling pathway (GO:0007210)2.40874934
141regulation of integrin-mediated signaling pathway (GO:2001044)2.40742039
142long-term synaptic potentiation (GO:0060291)2.40740613
143neurotransmitter transport (GO:0006836)2.40150748
144prostate gland growth (GO:0060736)2.39897617
145DNA ligation (GO:0006266)2.39820716
146insulin secretion (GO:0030073)2.39793832
147positive regulation of membrane potential (GO:0045838)2.39260683
148regulation of neurotransmitter secretion (GO:0046928)2.39156661
149negative regulation of neurotransmitter transport (GO:0051589)2.38915032
150histone mRNA metabolic process (GO:0008334)2.38299801
151mitotic cytokinesis (GO:0000281)2.37972500
152artery development (GO:0060840)2.37701656
153regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.37005173
154membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.36989312
155positive regulation of cardiac muscle cell differentiation (GO:2000727)2.35903828
156detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.35828582
157response to X-ray (GO:0010165)2.35414415
158drug catabolic process (GO:0042737)2.34915164
159negative regulation of DNA recombination (GO:0045910)2.34658291
160synaptic vesicle maturation (GO:0016188)2.34651395
161signal peptide processing (GO:0006465)2.34568802
162mitotic metaphase plate congression (GO:0007080)2.34027787
163regulation of coenzyme metabolic process (GO:0051196)2.33981403
164regulation of cofactor metabolic process (GO:0051193)2.33981403
165mitotic nuclear envelope disassembly (GO:0007077)2.33829258
166regulation of Rac protein signal transduction (GO:0035020)2.32987115
167regulation of synaptic transmission, GABAergic (GO:0032228)2.32437353
168energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.32272547
169ATP hydrolysis coupled proton transport (GO:0015991)2.32272547
170polyol transport (GO:0015791)2.31886587
171sodium ion transport (GO:0006814)2.31351981
172nonribosomal peptide biosynthetic process (GO:0019184)2.31099901
173negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.30734297
174regulation of chromosome segregation (GO:0051983)2.30306404
175regulation of acyl-CoA biosynthetic process (GO:0050812)2.30232049
176phosphate ion transmembrane transport (GO:0035435)2.30065024
177neurotransmitter metabolic process (GO:0042133)2.30000207
178regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.29197193
179phenol-containing compound biosynthetic process (GO:0046189)2.27876505
180regulation of transforming growth factor beta1 production (GO:0032908)2.27472692
181synaptic vesicle endocytosis (GO:0048488)2.27019774
182regulation of DNA-templated transcription, initiation (GO:2000142)2.26804114
183membrane disassembly (GO:0030397)2.26549685
184nuclear envelope disassembly (GO:0051081)2.26549685
185positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.25701370
186positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.25701370
187positive regulation of mitotic sister chromatid separation (GO:1901970)2.25701370
188hindbrain development (GO:0030902)2.25325286
189negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.24737043
190inositol phosphate catabolic process (GO:0071545)2.24275991
191positive regulation of actin filament depolymerization (GO:0030836)2.23743107
192regulation of glutamate receptor signaling pathway (GO:1900449)2.23671865
193regulation of growth hormone secretion (GO:0060123)2.23287562
194pyrimidine dimer repair (GO:0006290)2.22897170
195astrocyte differentiation (GO:0048708)2.21542717
196UDP-N-acetylglucosamine metabolic process (GO:0006047)2.20742943

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.75508605
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.01522203
3RBPJ_22232070_ChIP-Seq_NCS_Mouse2.73707182
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.55928425
5FLI1_27457419_Chip-Seq_LIVER_Mouse2.54822945
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.52804746
7* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.50314926
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.41800574
9E2F4_17652178_ChIP-ChIP_JURKAT_Human2.40403544
10VDR_22108803_ChIP-Seq_LS180_Human2.36306915
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.36295068
12HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.33927995
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.30944171
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.30335536
15ELK1_19687146_ChIP-ChIP_HELA_Human2.28212096
16PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.26009068
17PCGF2_27294783_Chip-Seq_ESCs_Mouse2.22276188
18PIAS1_25552417_ChIP-Seq_VCAP_Human2.20824724
19P300_19829295_ChIP-Seq_ESCs_Human2.10426769
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08787495
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.06738084
22E2F7_22180533_ChIP-Seq_HELA_Human2.01516549
23* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.99605966
24SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.98751419
25SMAD4_21799915_ChIP-Seq_A2780_Human1.98554964
26WT1_19549856_ChIP-ChIP_CCG9911_Human1.95160542
27GABP_17652178_ChIP-ChIP_JURKAT_Human1.90246115
28TAF15_26573619_Chip-Seq_HEK293_Human1.89319793
29PADI4_21655091_ChIP-ChIP_MCF-7_Human1.86288927
30NANOG_18555785_Chip-Seq_ESCs_Mouse1.83043669
31PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.82873868
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.82569664
33IGF1R_20145208_ChIP-Seq_DFB_Human1.82362572
34SUZ12_27294783_Chip-Seq_NPCs_Mouse1.79789844
35ZNF217_24962896_ChIP-Seq_MCF-7_Human1.78924730
36TOP2B_26459242_ChIP-Seq_MCF-7_Human1.78387128
37FOXM1_23109430_ChIP-Seq_U2OS_Human1.77746680
38OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.74791965
39FUS_26573619_Chip-Seq_HEK293_Human1.73521614
40TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.72326015
41* STAT3_23295773_ChIP-Seq_U87_Human1.71837335
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.70061829
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.69843043
44ZNF274_21170338_ChIP-Seq_K562_Hela1.64596718
45ER_23166858_ChIP-Seq_MCF-7_Human1.64102697
46MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.62693587
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.62482382
48AR_21572438_ChIP-Seq_LNCaP_Human1.61824657
49E2F1_18555785_Chip-Seq_ESCs_Mouse1.61743834
50PCGF2_27294783_Chip-Seq_NPCs_Mouse1.60196587
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55672156
52NFE2_27457419_Chip-Seq_LIVER_Mouse1.54248653
53P53_22387025_ChIP-Seq_ESCs_Mouse1.51695961
54* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.51166784
55EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.50962293
56RNF2_27304074_Chip-Seq_NSC_Mouse1.50306007
57EZH2_27294783_Chip-Seq_NPCs_Mouse1.49994834
58JUN_21703547_ChIP-Seq_K562_Human1.48889650
59CMYC_18555785_Chip-Seq_ESCs_Mouse1.48411067
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47656195
61SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.47314539
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47058383
63BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.46021323
64SUZ12_18555785_Chip-Seq_ESCs_Mouse1.44053494
65EST1_17652178_ChIP-ChIP_JURKAT_Human1.43894624
66AR_25329375_ChIP-Seq_VCAP_Human1.43204703
67STAT3_18555785_Chip-Seq_ESCs_Mouse1.42774159
68SOX2_18555785_Chip-Seq_ESCs_Mouse1.42061106
69EWS_26573619_Chip-Seq_HEK293_Human1.41352863
70TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.39794390
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.39285488
72VDR_23849224_ChIP-Seq_CD4+_Human1.38763985
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.38443965
74NR3C1_21868756_ChIP-Seq_MCF10A_Human1.37699074
75RXR_22108803_ChIP-Seq_LS180_Human1.37188514
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.36979312
77SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.36928409
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36730566
79BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36333722
80HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.36065891
81NMYC_18555785_Chip-Seq_ESCs_Mouse1.35558765
82NRF2_20460467_ChIP-Seq_MEFs_Mouse1.34597409
83NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.34597409
84RUNX2_22187159_ChIP-Seq_PCA_Human1.34319606
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34164471
86TCF4_22108803_ChIP-Seq_LS180_Human1.33556546
87SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.32306398
88CREB1_15753290_ChIP-ChIP_HEK293T_Human1.31795901
89TCF4_23295773_ChIP-Seq_U87_Human1.31377354
90* ARNT_22903824_ChIP-Seq_MCF-7_Human1.30863350
91TP53_18474530_ChIP-ChIP_U2OS_Human1.29895212
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.28628669
93ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.28555788
94P300_18555785_Chip-Seq_ESCs_Mouse1.28060139
95EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.27907852
96AR_21909140_ChIP-Seq_LNCAP_Human1.27761754
97FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.26206867
98CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.24988103
99BCAT_22108803_ChIP-Seq_LS180_Human1.24346511
100SOX2_21211035_ChIP-Seq_LN229_Gbm1.23637243
101BRD4_25478319_ChIP-Seq_HGPS_Human1.23540783
102TCF4_18268006_ChIP-ChIP_LS174T_Human1.21681877
103* OCT4_18555785_Chip-Seq_ESCs_Mouse1.21504572
104PRDM14_20953172_ChIP-Seq_ESCs_Human1.20014811
105FOXM1_26456572_ChIP-Seq_MCF-7_Human1.18576353
106* AHR_22903824_ChIP-Seq_MCF-7_Human1.18437944
107MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.17430825
108MYC_18940864_ChIP-ChIP_HL60_Human1.16445254
109RUNX1_27457419_Chip-Seq_LIVER_Mouse1.16267829
110SOX9_26525672_Chip-Seq_HEART_Mouse1.16031604
111KLF4_18555785_Chip-Seq_ESCs_Mouse1.14436461
112P53_22127205_ChIP-Seq_FIBROBLAST_Human1.14222418
113RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13963644
114SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13267123
115FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.12262611
116CDX2_22108803_ChIP-Seq_LS180_Human1.11361730
117CRX_20693478_ChIP-Seq_RETINA_Mouse1.11190633
118CDX2_19796622_ChIP-Seq_MESCs_Mouse1.11173563
119TBX3_20139965_ChIP-Seq_ESCs_Mouse1.11119442
120JARID2_20064375_ChIP-Seq_MESCs_Mouse1.10979256
121MYCN_18555785_ChIP-Seq_MESCs_Mouse1.10889643
122TBX3_20139965_ChIP-Seq_MESCs_Mouse1.10515786
123IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10160810
124CBP_20019798_ChIP-Seq_JUKART_Human1.10160810
125NANOG_19829295_ChIP-Seq_ESCs_Human1.09829299
126SOX2_19829295_ChIP-Seq_ESCs_Human1.09829299
127REST_21632747_ChIP-Seq_MESCs_Mouse1.09638077
128* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09220470
129SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.09020984
130ZFX_18555785_Chip-Seq_ESCs_Mouse1.08919029
131CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08728789
132TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.08629121
133CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07397598
134PU1_27457419_Chip-Seq_LIVER_Mouse1.07252531
135TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05871660
136SMAD1_18555785_Chip-Seq_ESCs_Mouse1.05476794
137CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.04339234
138YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03923260
139EZH2_27304074_Chip-Seq_ESCs_Mouse1.03519961
140* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03513084
141SOX2_16153702_ChIP-ChIP_HESCs_Human1.02091088
142FLI1_21867929_ChIP-Seq_TH2_Mouse1.00538139
143REST_19997604_ChIP-ChIP_NEURONS_Mouse1.00297979
144NELFA_20434984_ChIP-Seq_ESCs_Mouse0.99496072
145FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98796220
146TP63_19390658_ChIP-ChIP_HaCaT_Human0.98395884
147SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.98283744
148FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.97899307

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004043_abnormal_pH_regulation4.56919472
2MP0002876_abnormal_thyroid_physiology3.67123157
3MP0006292_abnormal_olfactory_placode3.51635263
4MP0003195_calcinosis3.05294169
5MP0005257_abnormal_intraocular_pressure2.99901751
6MP0002877_abnormal_melanocyte_morpholog2.94864566
7MP0009780_abnormal_chondrocyte_physiolo2.71137408
8MP0004270_analgesia2.68804219
9MP0001188_hyperpigmentation2.68797181
10MP0002009_preneoplasia2.63756982
11MP0010234_abnormal_vibrissa_follicle2.63134319
12MP0008789_abnormal_olfactory_epithelium2.59858271
13MP0002138_abnormal_hepatobiliary_system2.52800474
14MP0002735_abnormal_chemical_nociception2.47734101
15MP0010352_gastrointestinal_tract_polyps2.43583196
16MP0005499_abnormal_olfactory_system2.42187202
17MP0005394_taste/olfaction_phenotype2.42187202
18MP0006054_spinal_hemorrhage2.41459449
19MP0002734_abnormal_mechanical_nocicepti2.33427197
20MP0010386_abnormal_urinary_bladder2.29087116
21MP0003787_abnormal_imprinting2.28058847
22MP0000538_abnormal_urinary_bladder2.21899123
23MP0005646_abnormal_pituitary_gland2.19540365
24MP0003635_abnormal_synaptic_transmissio2.17029722
25MP0001177_atelectasis2.15707546
26MP0004885_abnormal_endolymph2.14505181
27MP0004859_abnormal_synaptic_plasticity2.10572295
28MP0002063_abnormal_learning/memory/cond2.08433116
29MP0002102_abnormal_ear_morphology2.07652719
30MP0004019_abnormal_vitamin_homeostasis2.05883457
31MP0001765_abnormal_ion_homeostasis1.99192145
32MP0009745_abnormal_behavioral_response1.99191231
33MP0005332_abnormal_amino_acid1.98001853
34MP0008058_abnormal_DNA_repair1.97809556
35MP0001756_abnormal_urination1.97560102
36MP0005171_absent_coat_pigmentation1.89974977
37MP0003221_abnormal_cardiomyocyte_apopto1.84894435
38MP0002234_abnormal_pharynx_morphology1.82188339
39MP0009046_muscle_twitch1.78772974
40MP0001968_abnormal_touch/_nociception1.75985870
41MP0005623_abnormal_meninges_morphology1.75104119
42MP0002736_abnormal_nociception_after1.74884372
43MP0003879_abnormal_hair_cell1.67660524
44MP0002064_seizures1.67399368
45MP0005367_renal/urinary_system_phenotyp1.67036632
46MP0000516_abnormal_urinary_system1.67036632
47MP0002572_abnormal_emotion/affect_behav1.66134312
48MP0003937_abnormal_limbs/digits/tail_de1.65563469
49MP0010678_abnormal_skin_adnexa1.63875194
50MP0001486_abnormal_startle_reflex1.60029379
51MP0001905_abnormal_dopamine_level1.59361938
52MP0001529_abnormal_vocalization1.53307494
53MP0002697_abnormal_eye_size1.48835126
54MP0002938_white_spotting1.48381383
55MP0003077_abnormal_cell_cycle1.48361467
56MP0003880_abnormal_central_pattern1.48204223
57MP0001293_anophthalmia1.44965861
58MP0010094_abnormal_chromosome_stability1.43826367
59MP0008007_abnormal_cellular_replicative1.43781695
60MP0000778_abnormal_nervous_system1.37746904
61MP0002233_abnormal_nose_morphology1.37057840
62MP0004782_abnormal_surfactant_physiolog1.35462667
63MP0001286_abnormal_eye_development1.35091737
64MP0005310_abnormal_salivary_gland1.34742454
65MP0009643_abnormal_urine_homeostasis1.34619693
66MP0002733_abnormal_thermal_nociception1.34567789
67MP0003385_abnormal_body_wall1.32689050
68MP0000647_abnormal_sebaceous_gland1.31446993
69MP0000428_abnormal_craniofacial_morphol1.31244944
70MP0002163_abnormal_gland_morphology1.30006035
71MP0005084_abnormal_gallbladder_morpholo1.28776205
72MP0002067_abnormal_sensory_capabilities1.27566938
73MP0005535_abnormal_body_temperature1.27173213
74MP0003111_abnormal_nucleus_morphology1.26935394
75MP0006072_abnormal_retinal_apoptosis1.25793421
76MP0001986_abnormal_taste_sensitivity1.22763343
77MP0008932_abnormal_embryonic_tissue1.22551182
78MP0005187_abnormal_penis_morphology1.22093574
79MP0004957_abnormal_blastocyst_morpholog1.20735483
80MP0005636_abnormal_mineral_homeostasis1.20105375
81MP0002084_abnormal_developmental_patter1.18135909
82MP0003755_abnormal_palate_morphology1.17574526
83MP0002177_abnormal_outer_ear1.17075621
84MP0005379_endocrine/exocrine_gland_phen1.16107073
85MP0001970_abnormal_pain_threshold1.15875798
86MP0005360_urolithiasis1.15258378
87MP0005408_hypopigmentation1.15042650
88MP0000383_abnormal_hair_follicle1.13343203
89MP0001963_abnormal_hearing_physiology1.13264236
90MP0001984_abnormal_olfaction1.13030509
91MP0003183_abnormal_peptide_metabolism1.12392206
92MP0004197_abnormal_fetal_growth/weight/1.12204884
93MP0003935_abnormal_craniofacial_develop1.11904947
94MP0002092_abnormal_eye_morphology1.11454434
95MP0002136_abnormal_kidney_physiology1.11145072
96MP0005391_vision/eye_phenotype1.10611267
97MP0002751_abnormal_autonomic_nervous1.09973273
98MP0002822_catalepsy1.09709335
99MP0005253_abnormal_eye_physiology1.08764934
100MP0002272_abnormal_nervous_system1.06222548
101MP0002090_abnormal_vision1.04431885
102MP0003890_abnormal_embryonic-extraembry1.04406506
103MP0004924_abnormal_behavior1.03160860
104MP0005386_behavior/neurological_phenoty1.03160860
105MP0006276_abnormal_autonomic_nervous1.02831655
106MP0009703_decreased_birth_body1.01711960
107MP0000613_abnormal_salivary_gland0.99399731
108MP0003567_abnormal_fetal_cardiomyocyte0.97512822
109MP0009697_abnormal_copulation0.95792721
110MP0002184_abnormal_innervation0.94969909
111MP0001346_abnormal_lacrimal_gland0.94941958
112MP0003693_abnormal_embryo_hatching0.94530011
113MP0000003_abnormal_adipose_tissue0.93817341
114MP0003941_abnormal_skin_development0.93023826
115MP0000049_abnormal_middle_ear0.92879549
116MP0001919_abnormal_reproductive_system0.92767896
117MP0005388_respiratory_system_phenotype0.92398202
118MP0002133_abnormal_respiratory_system0.92398202
119MP0002909_abnormal_adrenal_gland0.92378432
120MP0001485_abnormal_pinna_reflex0.91998251
121MP0002168_other_aberrant_phenotype0.91465884
122MP0001697_abnormal_embryo_size0.91443862
123MP0004811_abnormal_neuron_physiology0.91441002
124MP0000013_abnormal_adipose_tissue0.91006087
125MP0004742_abnormal_vestibular_system0.90571910
126MP0005197_abnormal_uvea_morphology0.90181252
127MP0002557_abnormal_social/conspecific_i0.89697346
128MP0001440_abnormal_grooming_behavior0.89687322
129MP0000230_abnormal_systemic_arterial0.88846182
130MP0005248_abnormal_Harderian_gland0.88656906
131MP0005389_reproductive_system_phenotype0.88622989
132MP0001542_abnormal_bone_strength0.88183686
133MP0008995_early_reproductive_senescence0.87515370
134MP0005645_abnormal_hypothalamus_physiol0.86296774
135MP0000372_irregular_coat_pigmentation0.85852925
136MP0001730_embryonic_growth_arrest0.85764030
137MP0003121_genomic_imprinting0.84235784
138MP0002928_abnormal_bile_duct0.84182137
139MP0001299_abnormal_eye_distance/0.84146222
140MP0001501_abnormal_sleep_pattern0.84074585
141MP0004264_abnormal_extraembryonic_tissu0.83717637
142MP0001672_abnormal_embryogenesis/_devel0.82314795
143MP0005380_embryogenesis_phenotype0.82314795
144MP0000427_abnormal_hair_cycle0.81553845
145MP0000631_abnormal_neuroendocrine_gland0.80815160
146MP0000569_abnormal_digit_pigmentation0.80082494
147MP0009053_abnormal_anal_canal0.79980092
148MP0002638_abnormal_pupillary_reflex0.79058954
149MP0010307_abnormal_tumor_latency0.78762072
150MP0004134_abnormal_chest_morphology0.78655461
151MP0002160_abnormal_reproductive_system0.78473421
152MP0003984_embryonic_growth_retardation0.77878835
153MP0002088_abnormal_embryonic_growth/wei0.77334377
154MP0008877_abnormal_DNA_methylation0.77312990
155MP0003786_premature_aging0.77209019
156MP0001664_abnormal_digestion0.77164130
157MP0002066_abnormal_motor_capabilities/c0.76777969
158MP0005275_abnormal_skin_tensile0.76331738
159MP0003861_abnormal_nervous_system0.75953431
160MP0000015_abnormal_ear_pigmentation0.75882805
161MP0001340_abnormal_eyelid_morphology0.75557863
162MP0005395_other_phenotype0.75046989
163MP0002139_abnormal_hepatobiliary_system0.73950923
164MP0008260_abnormal_autophagy0.73444173
165MP0000955_abnormal_spinal_cord0.73299591
166MP0000681_abnormal_thyroid_gland0.72026667
167MP0003119_abnormal_digestive_system0.71906963
168MP0002085_abnormal_embryonic_tissue0.71497556
169MP0009250_abnormal_appendicular_skeleto0.70945344
170MP0000350_abnormal_cell_proliferation0.70138219
171MP0008057_abnormal_DNA_replication0.69677362

Predicted human phenotypes

RankGene SetZ-score
1Increased circulating renin level (HP:0000848)4.67758421
2Hypokalemic alkalosis (HP:0001949)4.57814820
3Metabolic alkalosis (HP:0200114)4.55843094
4Hypomagnesemia (HP:0002917)4.50398254
5Hyperactive renin-angiotensin system (HP:0000841)4.42935974
6Gout (HP:0001997)4.23419341
7Abnormality of chloride homeostasis (HP:0011422)4.07815756
8Papillary thyroid carcinoma (HP:0002895)3.73634790
9Polyuria (HP:0000103)3.73421794
10Abnormal urine output (HP:0012590)3.52599090
11Thyroid carcinoma (HP:0002890)3.48198914
12Abnormality of renal excretion (HP:0011036)3.44875909
13Abnormality of magnesium homeostasis (HP:0004921)3.40331880
14Tetany (HP:0001281)3.37434145
15Hypothermia (HP:0002045)3.35830930
16Delayed epiphyseal ossification (HP:0002663)3.25617129
17Hyperaldosteronism (HP:0000859)3.21656605
18Hyperuricemia (HP:0002149)3.19538172
19Increased purine levels (HP:0004368)3.19538172
20Atonic seizures (HP:0010819)3.14325566
21Abnormality of renin-angiotensin system (HP:0000847)3.13188842
22Abnormal drinking behavior (HP:0030082)3.10738599
23Polydipsia (HP:0001959)3.10738599
24Hyperventilation (HP:0002883)3.09416257
25Cortical dysplasia (HP:0002539)3.06955245
26Limb dystonia (HP:0002451)3.04866803
27Proximal tubulopathy (HP:0000114)2.99091291
28Volvulus (HP:0002580)2.97023690
29Progressive inability to walk (HP:0002505)2.96729435
30Abnormal hair whorl (HP:0010721)2.92045052
31Hypokalemia (HP:0002900)2.90315048
32Focal motor seizures (HP:0011153)2.87729783
33Renal salt wasting (HP:0000127)2.81321968
34Alveolar cell carcinoma (HP:0006519)2.76965416
35Febrile seizures (HP:0002373)2.74092311
36Alkalosis (HP:0001948)2.69864689
37Neoplasm of the tracheobronchial system (HP:0100552)2.63052180
38Pheochromocytoma (HP:0002666)2.61151644
39Abnormality of the fovea (HP:0000493)2.58438796
40Renal tubular acidosis (HP:0001947)2.58320939
41Cerebellar dysplasia (HP:0007033)2.58029914
42Fetal akinesia sequence (HP:0001989)2.54711619
43Gait imbalance (HP:0002141)2.53327283
44Medulloblastoma (HP:0002885)2.49033621
45Congenital primary aphakia (HP:0007707)2.48737032
46Curly hair (HP:0002212)2.48232011
47Abnormality of potassium homeostasis (HP:0011042)2.46834537
48Termporal pattern (HP:0011008)2.43992444
49Insidious onset (HP:0003587)2.43992444
50Entropion (HP:0000621)2.39522711
51Abnormality of purine metabolism (HP:0004352)2.37388010
52Medial flaring of the eyebrow (HP:0010747)2.36608156
53Biliary tract neoplasm (HP:0100574)2.36303078
54Nephrogenic diabetes insipidus (HP:0009806)2.36183319
55Metaphyseal irregularity (HP:0003025)2.30770730
56Intestinal atresia (HP:0011100)2.29389912
57Disproportionate short-trunk short stature (HP:0003521)2.25925044
58Aqueductal stenosis (HP:0002410)2.21440330
59Neoplasm of the small intestine (HP:0100833)2.19762956
60Cutaneous melanoma (HP:0012056)2.19415895
61Amyotrophic lateral sclerosis (HP:0007354)2.18500009
62Abnormality of calcium-phosphate metabolism (HP:0100530)2.17975811
63Aplasia/Hypoplasia of the lens (HP:0008063)2.17879773
64Broad foot (HP:0001769)2.17150347
65Abnormality of the astrocytes (HP:0100707)2.15986752
66Astrocytoma (HP:0009592)2.15986752
67Genital tract atresia (HP:0001827)2.14751528
68Generalized hypopigmentation of hair (HP:0011358)2.14631397
69Renal cortical cysts (HP:0000803)2.10958470
70Absent eyebrow (HP:0002223)2.10767149
71Osteomalacia (HP:0002749)2.09584033
72Hyperglycinuria (HP:0003108)2.09579956
73Neuroendocrine neoplasm (HP:0100634)2.08551837
74Pulmonic stenosis (HP:0001642)2.08460362
75Widely patent fontanelles and sutures (HP:0004492)2.08453318
76Type II lissencephaly (HP:0007260)2.07959871
77Long clavicles (HP:0000890)2.06941245
78Abnormality of the labia minora (HP:0012880)2.06926258
79Vaginal atresia (HP:0000148)2.06430119
80Fair hair (HP:0002286)2.06272168
81Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.05254866
82Optic nerve hypoplasia (HP:0000609)2.04988379
83Epileptic encephalopathy (HP:0200134)2.04588632
84Progressive cerebellar ataxia (HP:0002073)2.04469954
85Abnormality of the musculature of the pelvis (HP:0001469)2.03320217
86Abnormality of the hip-girdle musculature (HP:0001445)2.03320217
87Neoplasm of the adrenal cortex (HP:0100641)2.03293736
88Blue irides (HP:0000635)2.02021568
89Menstrual irregularities (HP:0000858)2.01937524
90Irregular epiphyses (HP:0010582)2.01612588
91Tetraparesis (HP:0002273)1.99559032
92Inability to walk (HP:0002540)1.99297675
93Rhabdomyosarcoma (HP:0002859)1.98700899
94Hepatoblastoma (HP:0002884)1.97552827
95Sensory axonal neuropathy (HP:0003390)1.96141833
96Lissencephaly (HP:0001339)1.95068953
97Shawl scrotum (HP:0000049)1.93811039
98Decreased circulating renin level (HP:0003351)1.93715571
99Epiphyseal dysplasia (HP:0002656)1.93585816
100Large earlobe (HP:0009748)1.92993190
101Abnormal pancreas size (HP:0012094)1.92571002
102Potter facies (HP:0002009)1.91830769
103Facial shape deformation (HP:0011334)1.91830769
104Abnormality of the nasal septum (HP:0000419)1.90775809
105Spinal cord lesions (HP:0100561)1.90048031
106Syringomyelia (HP:0003396)1.90048031
107Abnormality of glutamine family amino acid metabolism (HP:0010902)1.88076177
108Hypophosphatemia (HP:0002148)1.87155496
109Submucous cleft hard palate (HP:0000176)1.87062174
110Cystic hygroma (HP:0000476)1.87058545
111Flat capital femoral epiphysis (HP:0003370)1.87041988
112Symptomatic seizures (HP:0011145)1.85530624
113Hyperglycinemia (HP:0002154)1.85287149
114Generalized aminoaciduria (HP:0002909)1.84347009
115Aplasia of the musculature (HP:0100854)1.80642427
116Abnormality of incisor morphology (HP:0011063)1.80302542
117Exercise-induced muscle cramps (HP:0003710)1.80264496
118Glucose intolerance (HP:0000833)1.79340591
119Relative macrocephaly (HP:0004482)1.79322040
120Hyperglycemia (HP:0003074)1.77601731
121Neoplasm of the rectum (HP:0100743)1.77426911
122Micropenis (HP:0000054)1.76770466
123Oligodactyly (hands) (HP:0001180)1.76027443
124Glycosuria (HP:0003076)1.75889026
125Abnormality of urine glucose concentration (HP:0011016)1.75889026
126Enlarged epiphyses (HP:0010580)1.75605126
127Abnormal auditory evoked potentials (HP:0006958)1.75103517
128Stillbirth (HP:0003826)1.74925227
129Barrel-shaped chest (HP:0001552)1.73894727
130Specific learning disability (HP:0001328)1.73809013
131Spinal muscular atrophy (HP:0007269)1.73730275
132Autoamputation (HP:0001218)1.73341874
133Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.72987871
134Abnormality of proline metabolism (HP:0010907)1.71857842
135Hydroxyprolinuria (HP:0003080)1.71857842
136Hyperphosphaturia (HP:0003109)1.71023989
137Enlarged kidneys (HP:0000105)1.70875397
138Congenital glaucoma (HP:0001087)1.70825989
139Poor coordination (HP:0002370)1.70539682
140Tongue fasciculations (HP:0001308)1.69122678
141Unilateral renal agenesis (HP:0000122)1.67622576
142Drooling (HP:0002307)1.67127038
143Excessive salivation (HP:0003781)1.67127038
144Neoplasm of the thyroid gland (HP:0100031)1.65584439
145Prostate neoplasm (HP:0100787)1.65494220
146Adrenal overactivity (HP:0002717)1.65409688
147Diminished movement (HP:0002374)1.65039174
148Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.64336926
149Glioma (HP:0009733)1.64170746
150Hypoplastic pelvis (HP:0008839)1.64111711
151Tubular atrophy (HP:0000092)1.63330888
152Hypoplasia of the fovea (HP:0007750)1.63233458
153Aplasia/Hypoplasia of the fovea (HP:0008060)1.63233458
154Decreased muscle mass (HP:0003199)1.62329687
155Short foot (HP:0001773)1.62266986
156Chromosomal breakage induced by crosslinking agents (HP:0003221)1.62021500
157Absence seizures (HP:0002121)1.61969022
158Abnormal eating behavior (HP:0100738)1.61254623
159Decreased testicular size (HP:0008734)1.61105149
160Neoplasm of the colon (HP:0100273)1.60995958
161Progressive external ophthalmoplegia (HP:0000590)1.60878188
162Absent speech (HP:0001344)1.60601417
163Failure to thrive in infancy (HP:0001531)1.60527524
164Spastic paraplegia (HP:0001258)1.60241918
165Aplasia/Hypoplasia of the brainstem (HP:0007362)1.60077741
166Hypoplasia of the brainstem (HP:0002365)1.60077741
167Breast carcinoma (HP:0003002)1.59413548
168Ependymoma (HP:0002888)1.58567068
169Labial hypoplasia (HP:0000066)1.57913749
170Chin dimple (HP:0010751)1.57842898
171Short middle phalanx of the 5th finger (HP:0004220)1.57826052
172Abnormal biliary tract morphology (HP:0012440)1.57762422
173Urinary urgency (HP:0000012)1.57360652
174Overlapping toe (HP:0001845)1.57335754
175Paraplegia (HP:0010550)1.57129884
176Short tibia (HP:0005736)1.57083496
177Abnormality of chromosome stability (HP:0003220)1.56876213
178Spastic diplegia (HP:0001264)1.56112045
179Thyroiditis (HP:0100646)1.55877264
180Aplasia/Hypoplasia of the tibia (HP:0005772)1.54867338
181Bifid tongue (HP:0010297)1.53736204
182Shoulder girdle muscle weakness (HP:0003547)1.53679570
183Scanning speech (HP:0002168)1.53513514
184Hip dysplasia (HP:0001385)1.53439513
185Deep philtrum (HP:0002002)1.52619574
186Colon cancer (HP:0003003)1.51104903
187Pelvic girdle muscle weakness (HP:0003749)1.51065397

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.90556215
2AKT33.65037831
3STK38L3.49270187
4WNK33.28733847
5WNK43.11076722
6OXSR12.90164821
7EIF2AK32.89076445
8FRK2.88719039
9TRIM282.85431711
10SGK22.39878320
11PBK2.25619779
12PLK22.19393740
13ZAK2.08003790
14BMPR21.97789340
15SGK4941.96564134
16SGK2231.96564134
17BCR1.92838811
18BRD41.87800063
19MKNK21.79146625
20MST41.79081333
21ERBB31.74269021
22NEK11.70199392
23MAP2K71.68115231
24SIK31.66791457
25STK391.61199982
26MAP3K141.59284385
27NTRK31.57382936
28PRPF4B1.57136387
29STK241.53424922
30SGK31.50894274
31CSNK1G11.50275618
32CSNK1G31.49649713
33LATS11.49423117
34IRAK31.49261114
35CSNK1A1L1.46140481
36MAP3K41.45382031
37LATS21.38029433
38INSRR1.37058664
39CCNB11.33428654
40TNIK1.31918082
41RPS6KA41.31834753
42BRSK21.27346799
43BUB11.25940049
44MARK11.24809198
45PDK21.24805146
46NEK61.22863568
47DYRK31.19405496
48PLK31.17376596
49WEE11.16320035
50PRKD31.16024062
51PAK61.12472468
52GRK51.05334960
53EPHA41.04147112
54EPHA31.03120064
55MINK11.02661416
56WNK10.97513590
57CDK60.96532661
58ERBB40.95909876
59SGK10.92740730
60MAP3K120.92326954
61NEK20.91345394
62STK380.90421751
63RAF10.89116264
64PDK30.88225441
65PDK40.88225441
66STK30.87010478
67NEK90.86886596
68PRKCE0.84481231
69TTK0.84191458
70ACVR1B0.83758861
71NUAK10.82031843
72PLK10.77042272
73MAPK130.76402513
74PRKCG0.73277994
75PTK2B0.73205512
76DYRK1A0.73177549
77TSSK60.72541412
78STK160.71761806
79YES10.70536778
80BMPR1B0.69585342
81KSR10.67546984
82VRK10.67178409
83MAP3K20.64540749
84PIM20.64033298
85RIPK40.63924718
86DAPK20.62632310
87SCYL20.61971387
88BRAF0.61472188
89ATM0.61258553
90FER0.58929875
91CDK80.58365904
92CDK30.57239930
93MAP3K60.57207309
94TAF10.56280835
95ADRBK20.55449893
96PRKCI0.54831628
97CAMK2A0.54561205
98PINK10.54258028
99CHUK0.53352434
100MAP3K30.53205788
101PIK3CA0.52886539
102NME10.49803833
103PRKCH0.49569396
104EEF2K0.49196907
105MKNK10.48848982
106CDK50.48125173
107RPS6KB10.47998177
108CHEK10.47184034
109EIF2AK20.46326449
110LIMK10.46305681
111ATR0.46305194
112CDC70.45217711
113CAMKK20.44180617
114CAMK2B0.44044247
115BRSK10.43458719
116MAP2K40.42065198
117PLK40.40798370
118CSNK1G20.38547212
119GSK3A0.37967386
120MAP3K50.37798539
121ICK0.37758906
122FGFR10.37259854
123DAPK10.37254131
124CSNK1D0.37118549
125HIPK20.36756090
126TRPM70.36705603
127AURKB0.36626985
128PRKAA10.33898762
129TNK20.33812220
130MAPK70.33761268
131CHEK20.33550686
132SRPK10.32946738
133MST1R0.32255953
134CDK140.30916871
135PIM10.30286458
136PDGFRA0.29195767
137CSNK1E0.28519538
138PAK30.27871673
139MAP2K10.27623032
140TGFBR20.27522569
141MAPKAPK50.27083078
142CAMK2G0.26869770
143MAPK100.26764031
144PRKCZ0.26415150
145EIF2AK10.25761404
146PRKACA0.24917710
147MAP3K90.24499980
148CSNK1A10.24338826
149RPS6KA30.23853393
150TXK0.23158412

Predicted pathways (KEGG)

RankGene SetZ-score
1Collecting duct acid secretion_Homo sapiens_hsa049663.92347619
2Non-homologous end-joining_Homo sapiens_hsa034503.47340058
3Synaptic vesicle cycle_Homo sapiens_hsa047212.96874197
4Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.48167083
5Nicotine addiction_Homo sapiens_hsa050332.39427615
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.36433269
7RNA transport_Homo sapiens_hsa030132.13622564
8Amphetamine addiction_Homo sapiens_hsa050312.12190452
9Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.10102457
10Ubiquitin mediated proteolysis_Homo sapiens_hsa041202.00587447
11p53 signaling pathway_Homo sapiens_hsa041151.97204672
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.96440410
13mRNA surveillance pathway_Homo sapiens_hsa030151.94593376
14Cell cycle_Homo sapiens_hsa041101.92935076
15Vibrio cholerae infection_Homo sapiens_hsa051101.90442220
16Oocyte meiosis_Homo sapiens_hsa041141.89719606
17Sulfur metabolism_Homo sapiens_hsa009201.88807648
18Long-term potentiation_Homo sapiens_hsa047201.87225672
19RNA degradation_Homo sapiens_hsa030181.85252089
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.84617514
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.84567235
22Butanoate metabolism_Homo sapiens_hsa006501.83951181
23Fanconi anemia pathway_Homo sapiens_hsa034601.77417616
24Vitamin B6 metabolism_Homo sapiens_hsa007501.76052296
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.75433273
26Insulin secretion_Homo sapiens_hsa049111.70983734
27Olfactory transduction_Homo sapiens_hsa047401.63388539
28Serotonergic synapse_Homo sapiens_hsa047261.63183640
29Cocaine addiction_Homo sapiens_hsa050301.59685861
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.59557030
31Dopaminergic synapse_Homo sapiens_hsa047281.59300125
32GABAergic synapse_Homo sapiens_hsa047271.58317484
33Selenocompound metabolism_Homo sapiens_hsa004501.57906640
34Spliceosome_Homo sapiens_hsa030401.57538630
35Rheumatoid arthritis_Homo sapiens_hsa053231.55258478
36Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.50908482
37Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.50415744
38Morphine addiction_Homo sapiens_hsa050321.47831548
39Nucleotide excision repair_Homo sapiens_hsa034201.38886703
40Taste transduction_Homo sapiens_hsa047421.37564705
41Vitamin digestion and absorption_Homo sapiens_hsa049771.33045207
42Glutamatergic synapse_Homo sapiens_hsa047241.32766205
43Alcoholism_Homo sapiens_hsa050341.30453416
44Mineral absorption_Homo sapiens_hsa049781.29857308
45Hedgehog signaling pathway_Homo sapiens_hsa043401.28500986
46Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.27726628
47Circadian entrainment_Homo sapiens_hsa047131.27093573
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.21613924
49Adherens junction_Homo sapiens_hsa045201.15903100
50SNARE interactions in vesicular transport_Homo sapiens_hsa041301.15173680
51Renin secretion_Homo sapiens_hsa049241.14454689
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.13294271
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.13139393
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12742007
55Protein export_Homo sapiens_hsa030601.11838903
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10733557
57Long-term depression_Homo sapiens_hsa047301.09707942
58Gastric acid secretion_Homo sapiens_hsa049711.05480774
59Thyroid hormone synthesis_Homo sapiens_hsa049181.05375070
60Cyanoamino acid metabolism_Homo sapiens_hsa004601.03362320
61Circadian rhythm_Homo sapiens_hsa047101.01252118
62Cholinergic synapse_Homo sapiens_hsa047251.00799428
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98705743
64MicroRNAs in cancer_Homo sapiens_hsa052060.97393956
65Salivary secretion_Homo sapiens_hsa049700.96973109
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96151928
67Phototransduction_Homo sapiens_hsa047440.95245667
68Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.94740790
69Wnt signaling pathway_Homo sapiens_hsa043100.93469633
70Basal transcription factors_Homo sapiens_hsa030220.91575306
71Cysteine and methionine metabolism_Homo sapiens_hsa002700.91310358
72Sphingolipid metabolism_Homo sapiens_hsa006000.89946963
73Thyroid cancer_Homo sapiens_hsa052160.88894319
74Colorectal cancer_Homo sapiens_hsa052100.88133541
75Endometrial cancer_Homo sapiens_hsa052130.87068418
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.86506293
77Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85661328
78Peroxisome_Homo sapiens_hsa041460.85635187
79Mismatch repair_Homo sapiens_hsa034300.83516975
80Inositol phosphate metabolism_Homo sapiens_hsa005620.82821611
81ErbB signaling pathway_Homo sapiens_hsa040120.82784065
82Steroid biosynthesis_Homo sapiens_hsa001000.81954203
83Regulation of autophagy_Homo sapiens_hsa041400.81532469
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.79398880
85Dorso-ventral axis formation_Homo sapiens_hsa043200.78821832
86Type I diabetes mellitus_Homo sapiens_hsa049400.78430075
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76562140
88N-Glycan biosynthesis_Homo sapiens_hsa005100.75632573
89Melanoma_Homo sapiens_hsa052180.74567818
90Prostate cancer_Homo sapiens_hsa052150.72249494
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.71871323
92Biosynthesis of amino acids_Homo sapiens_hsa012300.70536157
93Phagosome_Homo sapiens_hsa041450.70331389
94Protein digestion and absorption_Homo sapiens_hsa049740.69864321
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.69839418
96Lysine degradation_Homo sapiens_hsa003100.68052280
97Fatty acid elongation_Homo sapiens_hsa000620.68051143
98cAMP signaling pathway_Homo sapiens_hsa040240.66289405
99Proteoglycans in cancer_Homo sapiens_hsa052050.66221985
100Basal cell carcinoma_Homo sapiens_hsa052170.66034132
101Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64675385
102FoxO signaling pathway_Homo sapiens_hsa040680.64392980
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.62505931
104mTOR signaling pathway_Homo sapiens_hsa041500.61022424
105Arachidonic acid metabolism_Homo sapiens_hsa005900.60437217
106Viral carcinogenesis_Homo sapiens_hsa052030.59511497
107Type II diabetes mellitus_Homo sapiens_hsa049300.59057733
108Purine metabolism_Homo sapiens_hsa002300.58581384
109Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.57961025
110Proteasome_Homo sapiens_hsa030500.57845789
111RNA polymerase_Homo sapiens_hsa030200.57360819
112Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57321220
113Aldosterone synthesis and secretion_Homo sapiens_hsa049250.56164390
114Ether lipid metabolism_Homo sapiens_hsa005650.53644045
115Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53612216
116Axon guidance_Homo sapiens_hsa043600.52538288
117Propanoate metabolism_Homo sapiens_hsa006400.51671561
118Small cell lung cancer_Homo sapiens_hsa052220.51562488
119Melanogenesis_Homo sapiens_hsa049160.49662655
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.48999731
121Ras signaling pathway_Homo sapiens_hsa040140.48863510
122Calcium signaling pathway_Homo sapiens_hsa040200.47345169
123Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.46986294
124Phenylalanine metabolism_Homo sapiens_hsa003600.46664303
125Hippo signaling pathway_Homo sapiens_hsa043900.46214175
126TGF-beta signaling pathway_Homo sapiens_hsa043500.45741499
127Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45205942
128Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44729829
129cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44348333
130Oxytocin signaling pathway_Homo sapiens_hsa049210.44017982
131Choline metabolism in cancer_Homo sapiens_hsa052310.43493663
132Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.42992644
133Tight junction_Homo sapiens_hsa045300.42578354
134Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.42154494
135Pentose phosphate pathway_Homo sapiens_hsa000300.41894417
136Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40816304
137Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40771998
138Glycerophospholipid metabolism_Homo sapiens_hsa005640.39886685
139Pathways in cancer_Homo sapiens_hsa052000.39215085
140Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38394851
141Base excision repair_Homo sapiens_hsa034100.38202755
142Renin-angiotensin system_Homo sapiens_hsa046140.38001610
143Glioma_Homo sapiens_hsa052140.36639483
144Prolactin signaling pathway_Homo sapiens_hsa049170.36063789
145Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.35517885
146Glucagon signaling pathway_Homo sapiens_hsa049220.34143182
147Pyruvate metabolism_Homo sapiens_hsa006200.33876737
148GnRH signaling pathway_Homo sapiens_hsa049120.32553616
149Gap junction_Homo sapiens_hsa045400.31920074
150MAPK signaling pathway_Homo sapiens_hsa040100.31898958
151Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.31659803
152Vascular smooth muscle contraction_Homo sapiens_hsa042700.30407742

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »