

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chromatin remodeling at centromere (GO:0031055) | 5.32800303 |
| 2 | histone exchange (GO:0043486) | 5.17604904 |
| 3 | CENP-A containing nucleosome assembly (GO:0034080) | 5.03530138 |
| 4 | establishment of integrated proviral latency (GO:0075713) | 4.87749834 |
| 5 | DNA double-strand break processing (GO:0000729) | 4.67758222 |
| 6 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.49245197 |
| 7 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.49245197 |
| 8 | regulation of helicase activity (GO:0051095) | 4.47900069 |
| 9 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.39637016 |
| 10 | DNA replication checkpoint (GO:0000076) | 4.35330138 |
| 11 | regulation of gene silencing by RNA (GO:0060966) | 4.19315086 |
| 12 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.19315086 |
| 13 | regulation of gene silencing by miRNA (GO:0060964) | 4.19315086 |
| 14 | DNA replication-independent nucleosome organization (GO:0034724) | 4.14517477 |
| 15 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.14517477 |
| 16 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 4.07904141 |
| 17 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 4.07904141 |
| 18 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 4.07904141 |
| 19 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 4.07904141 |
| 20 | negative regulation of sister chromatid segregation (GO:0033046) | 4.07904141 |
| 21 | negative regulation of chromosome segregation (GO:0051985) | 4.00873384 |
| 22 | pre-miRNA processing (GO:0031054) | 3.96727419 |
| 23 | telomere maintenance via telomerase (GO:0007004) | 3.94427608 |
| 24 | IMP biosynthetic process (GO:0006188) | 3.93916011 |
| 25 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.85529590 |
| 26 | mitotic metaphase plate congression (GO:0007080) | 3.80927402 |
| 27 | spindle checkpoint (GO:0031577) | 3.79303847 |
| 28 | heterochromatin organization (GO:0070828) | 3.79189808 |
| 29 | protein localization to kinetochore (GO:0034501) | 3.77079431 |
| 30 | mitotic spindle checkpoint (GO:0071174) | 3.68477253 |
| 31 | establishment of viral latency (GO:0019043) | 3.67661657 |
| 32 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.64631078 |
| 33 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.64631078 |
| 34 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.64631078 |
| 35 | chaperone-mediated protein transport (GO:0072321) | 3.62560984 |
| 36 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.60510308 |
| 37 | IMP metabolic process (GO:0046040) | 3.60009836 |
| 38 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.58894627 |
| 39 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.58894627 |
| 40 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.55491653 |
| 41 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.55491653 |
| 42 | L-serine metabolic process (GO:0006563) | 3.53619122 |
| 43 | regulation of sister chromatid segregation (GO:0033045) | 3.49094299 |
| 44 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.49094299 |
| 45 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.49094299 |
| 46 | mitotic spindle assembly checkpoint (GO:0007094) | 3.45585422 |
| 47 | purine nucleobase biosynthetic process (GO:0009113) | 3.45234736 |
| 48 | protein complex localization (GO:0031503) | 3.44550291 |
| 49 | DNA strand elongation (GO:0022616) | 3.38851371 |
| 50 | mitotic G2/M transition checkpoint (GO:0044818) | 3.38484679 |
| 51 | spindle assembly checkpoint (GO:0071173) | 3.38238990 |
| 52 | ribosome assembly (GO:0042255) | 3.37514555 |
| 53 | negative regulation of telomerase activity (GO:0051974) | 3.37343538 |
| 54 | negative regulation of DNA recombination (GO:0045910) | 3.35715921 |
| 55 | ATP-dependent chromatin remodeling (GO:0043044) | 3.34371637 |
| 56 | nuclear pore complex assembly (GO:0051292) | 3.33282666 |
| 57 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.33213454 |
| 58 | negative regulation of mitosis (GO:0045839) | 3.30570416 |
| 59 | metaphase plate congression (GO:0051310) | 3.30524810 |
| 60 | proteasome assembly (GO:0043248) | 3.26794389 |
| 61 | anterior/posterior axis specification, embryo (GO:0008595) | 3.23979202 |
| 62 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.22876092 |
| 63 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.22876092 |
| 64 | regulation of chromosome segregation (GO:0051983) | 3.22606997 |
| 65 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.20453693 |
| 66 | RNA-dependent DNA replication (GO:0006278) | 3.20318650 |
| 67 | DNA damage response, detection of DNA damage (GO:0042769) | 3.19217252 |
| 68 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.17705811 |
| 69 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.17695514 |
| 70 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.15830068 |
| 71 | synapsis (GO:0007129) | 3.14310006 |
| 72 | regulation of centriole replication (GO:0046599) | 3.13858699 |
| 73 | nucleobase biosynthetic process (GO:0046112) | 3.11029277 |
| 74 | nuclear pore organization (GO:0006999) | 3.09781658 |
| 75 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.09534155 |
| 76 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.07556036 |
| 77 | termination of RNA polymerase III transcription (GO:0006386) | 3.07556036 |
| 78 | telomere maintenance via telomere lengthening (GO:0010833) | 3.06963658 |
| 79 | response to X-ray (GO:0010165) | 3.04444433 |
| 80 | non-recombinational repair (GO:0000726) | 3.02778899 |
| 81 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.02778899 |
| 82 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.00910305 |
| 83 | lysine catabolic process (GO:0006554) | 3.00011276 |
| 84 | lysine metabolic process (GO:0006553) | 3.00011276 |
| 85 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.98856405 |
| 86 | regulation of histone H3-K9 methylation (GO:0051570) | 2.97301531 |
| 87 | negative regulation of nuclear division (GO:0051784) | 2.97243718 |
| 88 | replication fork processing (GO:0031297) | 2.94084386 |
| 89 | regulation of spindle checkpoint (GO:0090231) | 2.92943567 |
| 90 | histone mRNA metabolic process (GO:0008334) | 2.92552300 |
| 91 | rRNA modification (GO:0000154) | 2.91873081 |
| 92 | mitotic sister chromatid cohesion (GO:0007064) | 2.90958639 |
| 93 | kinetochore organization (GO:0051383) | 2.89580798 |
| 94 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.89523693 |
| 95 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) | 2.89399432 |
| 96 | telomere maintenance via recombination (GO:0000722) | 2.89065474 |
| 97 | chromatin assembly or disassembly (GO:0006333) | 2.89019148 |
| 98 | mitotic recombination (GO:0006312) | 2.87429020 |
| 99 | paraxial mesoderm development (GO:0048339) | 2.85409878 |
| 100 | kinetochore assembly (GO:0051382) | 2.81638560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.69100646 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.80989978 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.76629069 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.35368241 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.08114597 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.05341610 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.86536352 |
| 8 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.85832820 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.84804464 |
| 10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.65989919 |
| 11 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.65037641 |
| 12 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.59182885 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.39188507 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.34293090 |
| 15 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.26640469 |
| 16 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.17064270 |
| 17 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.16250345 |
| 18 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.16250345 |
| 19 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.16250345 |
| 20 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.15106992 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.11390132 |
| 22 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.11327410 |
| 23 | FUS_26573619_Chip-Seq_HEK293_Human | 2.07502019 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.05155606 |
| 25 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.04477008 |
| 26 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.03869078 |
| 27 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 2.00339530 |
| 28 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.87823384 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.85736579 |
| 30 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.82763236 |
| 31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.82585624 |
| 32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.81491291 |
| 33 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.70889114 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.70833690 |
| 35 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.70296474 |
| 36 | VDR_22108803_ChIP-Seq_LS180_Human | 1.69732086 |
| 37 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69686608 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.68929528 |
| 39 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.67773608 |
| 40 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.66251738 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.63818957 |
| 42 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.60672977 |
| 43 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58692587 |
| 44 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.58144124 |
| 45 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.57505209 |
| 46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.57300545 |
| 47 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.56355122 |
| 48 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52531135 |
| 49 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.51904918 |
| 50 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.50160708 |
| 51 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.46558819 |
| 52 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.42511792 |
| 53 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.41737188 |
| 54 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.37911700 |
| 55 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.34985784 |
| 56 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.34771427 |
| 57 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.31859825 |
| 58 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31127518 |
| 59 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.27026575 |
| 60 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.25946126 |
| 61 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.24870066 |
| 62 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.23629645 |
| 63 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.22528554 |
| 64 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.21584099 |
| 65 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.18366981 |
| 66 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.18208641 |
| 67 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.18149065 |
| 68 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.17937442 |
| 69 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.14138513 |
| 70 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.13388257 |
| 71 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.11396095 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10205045 |
| 73 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08098529 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.06826783 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.06488662 |
| 76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.06232171 |
| 77 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03477048 |
| 78 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.03463651 |
| 79 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.03241405 |
| 80 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.03087059 |
| 81 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.00809022 |
| 82 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.99335720 |
| 83 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.98212126 |
| 84 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.97316727 |
| 85 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.96727768 |
| 86 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96727768 |
| 87 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.95830786 |
| 88 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.92629986 |
| 89 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.92034830 |
| 90 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.91497752 |
| 91 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.89509960 |
| 92 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88624715 |
| 93 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.86927923 |
| 94 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.86313357 |
| 95 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.85219588 |
| 96 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.85208532 |
| 97 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.84424514 |
| 98 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.83972561 |
| 99 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.81275412 |
| 100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.80421003 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003941_abnormal_skin_development | 5.43175705 |
| 2 | MP0003693_abnormal_embryo_hatching | 3.86870288 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.76083461 |
| 4 | MP0010094_abnormal_chromosome_stability | 3.37732050 |
| 5 | MP0004957_abnormal_blastocyst_morpholog | 3.34299941 |
| 6 | MP0002254_reproductive_system_inflammat | 3.30667888 |
| 7 | MP0008058_abnormal_DNA_repair | 3.22166522 |
| 8 | MP0001188_hyperpigmentation | 3.16593631 |
| 9 | MP0003111_abnormal_nucleus_morphology | 3.05612593 |
| 10 | MP0003890_abnormal_embryonic-extraembry | 2.92305952 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.89258090 |
| 12 | MP0003718_maternal_effect | 2.70326031 |
| 13 | MP0003136_yellow_coat_color | 2.61741568 |
| 14 | MP0008057_abnormal_DNA_replication | 2.55093306 |
| 15 | MP0008932_abnormal_embryonic_tissue | 2.40867192 |
| 16 | MP0008007_abnormal_cellular_replicative | 2.37778987 |
| 17 | MP0003077_abnormal_cell_cycle | 2.35876261 |
| 18 | MP0001293_anophthalmia | 2.32080194 |
| 19 | MP0009672_abnormal_birth_weight | 2.01814715 |
| 20 | MP0003567_abnormal_fetal_cardiomyocyte | 2.00159815 |
| 21 | MP0005410_abnormal_fertilization | 1.75437296 |
| 22 | MP0003123_paternal_imprinting | 1.71554025 |
| 23 | MP0006072_abnormal_retinal_apoptosis | 1.71398664 |
| 24 | MP0009697_abnormal_copulation | 1.67122504 |
| 25 | MP0003937_abnormal_limbs/digits/tail_de | 1.66310335 |
| 26 | MP0003119_abnormal_digestive_system | 1.64408008 |
| 27 | MP0003787_abnormal_imprinting | 1.63931276 |
| 28 | MP0003315_abnormal_perineum_morphology | 1.61555538 |
| 29 | MP0003121_genomic_imprinting | 1.54977518 |
| 30 | MP0000579_abnormal_nail_morphology | 1.53359049 |
| 31 | MP0001984_abnormal_olfaction | 1.47861920 |
| 32 | MP0001730_embryonic_growth_arrest | 1.45541940 |
| 33 | MP0001529_abnormal_vocalization | 1.37451615 |
| 34 | MP0004133_heterotaxia | 1.37366991 |
| 35 | MP0003786_premature_aging | 1.34066957 |
| 36 | MP0001929_abnormal_gametogenesis | 1.29490072 |
| 37 | MP0002084_abnormal_developmental_patter | 1.28825153 |
| 38 | MP0010352_gastrointestinal_tract_polyps | 1.28642411 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.27851513 |
| 40 | MP0002085_abnormal_embryonic_tissue | 1.27807874 |
| 41 | MP0000350_abnormal_cell_proliferation | 1.26837610 |
| 42 | MP0001286_abnormal_eye_development | 1.25596855 |
| 43 | MP0009703_decreased_birth_body | 1.24695503 |
| 44 | MP0001485_abnormal_pinna_reflex | 1.22643241 |
| 45 | MP0002697_abnormal_eye_size | 1.21425119 |
| 46 | MP0002102_abnormal_ear_morphology | 1.19354446 |
| 47 | MP0002938_white_spotting | 1.17007140 |
| 48 | MP0002160_abnormal_reproductive_system | 1.15632775 |
| 49 | MP0001177_atelectasis | 1.15209372 |
| 50 | MP0010307_abnormal_tumor_latency | 1.14835299 |
| 51 | MP0001672_abnormal_embryogenesis/_devel | 1.14116931 |
| 52 | MP0005380_embryogenesis_phenotype | 1.14116931 |
| 53 | MP0001697_abnormal_embryo_size | 1.13118720 |
| 54 | MP0002233_abnormal_nose_morphology | 1.10670650 |
| 55 | MP0001299_abnormal_eye_distance/ | 1.09580277 |
| 56 | MP0002210_abnormal_sex_determination | 1.09304371 |
| 57 | MP0010030_abnormal_orbit_morphology | 1.07141402 |
| 58 | MP0005499_abnormal_olfactory_system | 1.07054187 |
| 59 | MP0005394_taste/olfaction_phenotype | 1.07054187 |
| 60 | MP0002090_abnormal_vision | 1.06139027 |
| 61 | MP0003698_abnormal_male_reproductive | 1.06038387 |
| 62 | MP0001145_abnormal_male_reproductive | 1.04897961 |
| 63 | MP0002736_abnormal_nociception_after | 1.00540860 |
| 64 | MP0002751_abnormal_autonomic_nervous | 0.99752350 |
| 65 | MP0000653_abnormal_sex_gland | 0.97225576 |
| 66 | MP0004197_abnormal_fetal_growth/weight/ | 0.96994602 |
| 67 | MP0005395_other_phenotype | 0.96480031 |
| 68 | MP0002111_abnormal_tail_morphology | 0.92316259 |
| 69 | MP0002080_prenatal_lethality | 0.92287840 |
| 70 | MP0005377_hearing/vestibular/ear_phenot | 0.90659984 |
| 71 | MP0003878_abnormal_ear_physiology | 0.90659984 |
| 72 | MP0003984_embryonic_growth_retardation | 0.90073947 |
| 73 | MP0002088_abnormal_embryonic_growth/wei | 0.89850093 |
| 74 | MP0000049_abnormal_middle_ear | 0.89809007 |
| 75 | MP0008789_abnormal_olfactory_epithelium | 0.88523280 |
| 76 | MP0002277_abnormal_respiratory_mucosa | 0.87717490 |
| 77 | MP0008995_early_reproductive_senescence | 0.86466017 |
| 78 | MP0000537_abnormal_urethra_morphology | 0.80331590 |
| 79 | MP0002796_impaired_skin_barrier | 0.79846731 |
| 80 | MP0003806_abnormal_nucleotide_metabolis | 0.78014751 |
| 81 | MP0003186_abnormal_redox_activity | 0.78000743 |
| 82 | MP0000631_abnormal_neuroendocrine_gland | 0.77473676 |
| 83 | MP0002161_abnormal_fertility/fecundity | 0.76228247 |
| 84 | MP0000428_abnormal_craniofacial_morphol | 0.74276567 |
| 85 | MP0003861_abnormal_nervous_system | 0.72412021 |
| 86 | MP0003122_maternal_imprinting | 0.71062717 |
| 87 | MP0003755_abnormal_palate_morphology | 0.69895917 |
| 88 | MP0000313_abnormal_cell_death | 0.69653550 |
| 89 | MP0002086_abnormal_extraembryonic_tissu | 0.69603624 |
| 90 | MP0005389_reproductive_system_phenotype | 0.69177559 |
| 91 | MP0006036_abnormal_mitochondrial_physio | 0.68677032 |
| 92 | MP0005253_abnormal_eye_physiology | 0.67625805 |
| 93 | MP0005391_vision/eye_phenotype | 0.67358257 |
| 94 | MP0005551_abnormal_eye_electrophysiolog | 0.67265032 |
| 95 | MP0000762_abnormal_tongue_morphology | 0.66795442 |
| 96 | MP0003137_abnormal_impulse_conducting | 0.66229086 |
| 97 | MP0004019_abnormal_vitamin_homeostasis | 0.63552513 |
| 98 | MP0001119_abnormal_female_reproductive | 0.61570240 |
| 99 | MP0003938_abnormal_ear_development | 0.61441318 |
| 100 | MP0000432_abnormal_head_morphology | 0.60286867 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Colon cancer (HP:0003003) | 4.58685632 |
| 2 | Abnormality of the labia minora (HP:0012880) | 4.54034170 |
| 3 | Septo-optic dysplasia (HP:0100842) | 3.87398470 |
| 4 | Meckel diverticulum (HP:0002245) | 3.32713215 |
| 5 | Abnormal lung lobation (HP:0002101) | 3.29353229 |
| 6 | Abnormality of chromosome stability (HP:0003220) | 3.26670876 |
| 7 | Abnormality of the ileum (HP:0001549) | 3.21544260 |
| 8 | Chromsome breakage (HP:0040012) | 3.21350256 |
| 9 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.13709405 |
| 10 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.08573463 |
| 11 | Birth length less than 3rd percentile (HP:0003561) | 3.01139247 |
| 12 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.94344152 |
| 13 | Multiple enchondromatosis (HP:0005701) | 2.90377797 |
| 14 | Embryonal renal neoplasm (HP:0011794) | 2.89676773 |
| 15 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.88060240 |
| 16 | Abnormality of the preputium (HP:0100587) | 2.75801378 |
| 17 | Bilateral microphthalmos (HP:0007633) | 2.74985866 |
| 18 | Chronic bronchitis (HP:0004469) | 2.63989499 |
| 19 | Ependymoma (HP:0002888) | 2.62980662 |
| 20 | Hypoglycemic seizures (HP:0002173) | 2.60168751 |
| 21 | Abnormality of serum amino acid levels (HP:0003112) | 2.57243740 |
| 22 | Hyperglycinemia (HP:0002154) | 2.52358024 |
| 23 | Abnormality of methionine metabolism (HP:0010901) | 2.52321350 |
| 24 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.50015648 |
| 25 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.48409247 |
| 26 | Hepatoblastoma (HP:0002884) | 2.46279803 |
| 27 | Small intestinal stenosis (HP:0012848) | 2.45649357 |
| 28 | Duodenal stenosis (HP:0100867) | 2.45649357 |
| 29 | Stenosis of the external auditory canal (HP:0000402) | 2.41007298 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.40903620 |
| 31 | Rhabdomyosarcoma (HP:0002859) | 2.39375886 |
| 32 | Lipid accumulation in hepatocytes (HP:0006561) | 2.36877840 |
| 33 | Facial cleft (HP:0002006) | 2.36228537 |
| 34 | Abnormality of the duodenum (HP:0002246) | 2.34727975 |
| 35 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.32173545 |
| 36 | Bifid tongue (HP:0010297) | 2.31504754 |
| 37 | Absent septum pellucidum (HP:0001331) | 2.30653309 |
| 38 | Optic nerve hypoplasia (HP:0000609) | 2.28751299 |
| 39 | Medulloblastoma (HP:0002885) | 2.28301711 |
| 40 | Volvulus (HP:0002580) | 2.27987591 |
| 41 | Abnormality of the septum pellucidum (HP:0007375) | 2.27299419 |
| 42 | Abnormality of homocysteine metabolism (HP:0010919) | 2.24004685 |
| 43 | Homocystinuria (HP:0002156) | 2.24004685 |
| 44 | Methylmalonic acidemia (HP:0002912) | 2.23150936 |
| 45 | Agnosia (HP:0010524) | 2.22708872 |
| 46 | Spastic diplegia (HP:0001264) | 2.19410659 |
| 47 | Maternal diabetes (HP:0009800) | 2.17889812 |
| 48 | Abnormal hair whorl (HP:0010721) | 2.17615588 |
| 49 | Choanal stenosis (HP:0000452) | 2.17317944 |
| 50 | Absent radius (HP:0003974) | 2.14648946 |
| 51 | Acute encephalopathy (HP:0006846) | 2.14239161 |
| 52 | Acute necrotizing encephalopathy (HP:0006965) | 2.12934319 |
| 53 | Absent eyebrow (HP:0002223) | 2.11751931 |
| 54 | Carpal bone hypoplasia (HP:0001498) | 2.11289074 |
| 55 | Abnormality of glycine metabolism (HP:0010895) | 2.10833427 |
| 56 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.10833427 |
| 57 | Triphalangeal thumb (HP:0001199) | 2.10784920 |
| 58 | Ectopic kidney (HP:0000086) | 2.08884247 |
| 59 | Biliary tract neoplasm (HP:0100574) | 2.07948114 |
| 60 | Breast aplasia (HP:0100783) | 2.06070467 |
| 61 | Esophageal atresia (HP:0002032) | 2.05432708 |
| 62 | Reduced antithrombin III activity (HP:0001976) | 2.05408738 |
| 63 | Megaloblastic anemia (HP:0001889) | 2.04137644 |
| 64 | Hyperglycinuria (HP:0003108) | 2.03993119 |
| 65 | Intestinal atresia (HP:0011100) | 2.01247220 |
| 66 | Sloping forehead (HP:0000340) | 2.01072575 |
| 67 | Sensory axonal neuropathy (HP:0003390) | 2.00199190 |
| 68 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.99474902 |
| 69 | Absent forearm bone (HP:0003953) | 1.98214746 |
| 70 | Aplasia involving forearm bones (HP:0009822) | 1.98214746 |
| 71 | Neoplasm of the colon (HP:0100273) | 1.96339595 |
| 72 | Abolished electroretinogram (ERG) (HP:0000550) | 1.96088321 |
| 73 | Glioma (HP:0009733) | 1.95570743 |
| 74 | Cellular immunodeficiency (HP:0005374) | 1.95152204 |
| 75 | Supernumerary spleens (HP:0009799) | 1.95055120 |
| 76 | Anophthalmia (HP:0000528) | 1.94842927 |
| 77 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.88709546 |
| 78 | Neoplasm of the adrenal gland (HP:0100631) | 1.88207263 |
| 79 | Abnormal number of incisors (HP:0011064) | 1.87689768 |
| 80 | Neoplasm of the adrenal cortex (HP:0100641) | 1.87655366 |
| 81 | Reticulocytopenia (HP:0001896) | 1.86016231 |
| 82 | Horseshoe kidney (HP:0000085) | 1.85284140 |
| 83 | Aplastic anemia (HP:0001915) | 1.84616289 |
| 84 | Gastrointestinal atresia (HP:0002589) | 1.82807333 |
| 85 | Symptomatic seizures (HP:0011145) | 1.80873461 |
| 86 | Selective tooth agenesis (HP:0001592) | 1.80337736 |
| 87 | Methylmalonic aciduria (HP:0012120) | 1.79942090 |
| 88 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.79284741 |
| 89 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.79284741 |
| 90 | Absent thumb (HP:0009777) | 1.78955788 |
| 91 | Pendular nystagmus (HP:0012043) | 1.78090622 |
| 92 | Median cleft lip (HP:0000161) | 1.77827461 |
| 93 | Neoplasm of the oral cavity (HP:0100649) | 1.76435796 |
| 94 | Hypoplastic female external genitalia (HP:0012815) | 1.74927432 |
| 95 | Myelomeningocele (HP:0002475) | 1.74729592 |
| 96 | Oral leukoplakia (HP:0002745) | 1.74010147 |
| 97 | Cleft eyelid (HP:0000625) | 1.73800621 |
| 98 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.73492434 |
| 99 | Abnormality of the clitoris (HP:0000056) | 1.73385788 |
| 100 | Clubbing of toes (HP:0100760) | 1.73071288 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDC7 | 4.16560516 |
| 2 | BUB1 | 3.77993373 |
| 3 | TNIK | 3.55310890 |
| 4 | ZAK | 3.47613554 |
| 5 | TTK | 3.21828041 |
| 6 | MKNK2 | 3.10545302 |
| 7 | PBK | 2.92162589 |
| 8 | TSSK6 | 2.66119333 |
| 9 | SRPK1 | 2.51770020 |
| 10 | WNK3 | 2.45551663 |
| 11 | PLK3 | 2.45430816 |
| 12 | MKNK1 | 2.39692730 |
| 13 | VRK2 | 2.28703112 |
| 14 | PLK4 | 2.24190847 |
| 15 | TAF1 | 2.23010220 |
| 16 | MST4 | 2.15934640 |
| 17 | PINK1 | 2.15738362 |
| 18 | NUAK1 | 2.09364490 |
| 19 | BMPR1B | 1.84585433 |
| 20 | VRK1 | 1.83408667 |
| 21 | ACVR1B | 1.83399422 |
| 22 | TRIM28 | 1.82858020 |
| 23 | BRSK2 | 1.72714986 |
| 24 | PLK1 | 1.71160609 |
| 25 | STK16 | 1.55962736 |
| 26 | EIF2AK3 | 1.45049045 |
| 27 | NEK1 | 1.42423143 |
| 28 | NME1 | 1.36579128 |
| 29 | DYRK2 | 1.31549690 |
| 30 | DYRK3 | 1.30964118 |
| 31 | STK38L | 1.26978624 |
| 32 | NEK2 | 1.25190831 |
| 33 | WEE1 | 1.25093864 |
| 34 | NLK | 1.19413120 |
| 35 | TLK1 | 1.09851004 |
| 36 | MARK3 | 1.08696168 |
| 37 | CSNK1G1 | 1.04322203 |
| 38 | ERBB4 | 1.01174453 |
| 39 | CASK | 1.00796864 |
| 40 | ATR | 0.99941207 |
| 41 | CHEK2 | 0.97155301 |
| 42 | ALK | 0.96863624 |
| 43 | GRK1 | 0.93125500 |
| 44 | ATM | 0.91842040 |
| 45 | AURKB | 0.88824469 |
| 46 | STK3 | 0.87915858 |
| 47 | LATS1 | 0.87672143 |
| 48 | CDK19 | 0.87633230 |
| 49 | PNCK | 0.84737763 |
| 50 | FGFR2 | 0.75178194 |
| 51 | STK4 | 0.74508730 |
| 52 | EIF2AK1 | 0.74311196 |
| 53 | OXSR1 | 0.74275960 |
| 54 | FGFR1 | 0.73716205 |
| 55 | CHEK1 | 0.71935952 |
| 56 | PDK2 | 0.70632944 |
| 57 | RPS6KA5 | 0.69985961 |
| 58 | CDK3 | 0.65384266 |
| 59 | BRSK1 | 0.64354807 |
| 60 | CSNK1G2 | 0.63211842 |
| 61 | MAP3K10 | 0.62902322 |
| 62 | TGFBR1 | 0.62273382 |
| 63 | TIE1 | 0.61816466 |
| 64 | CSNK1E | 0.57722328 |
| 65 | PLK2 | 0.56166137 |
| 66 | FRK | 0.52675643 |
| 67 | NME2 | 0.52468439 |
| 68 | CSNK1G3 | 0.52143488 |
| 69 | PRKCG | 0.51961101 |
| 70 | EIF2AK2 | 0.51418395 |
| 71 | PRKDC | 0.48974615 |
| 72 | PASK | 0.48949400 |
| 73 | CDK7 | 0.46531755 |
| 74 | CSNK2A2 | 0.46274131 |
| 75 | RPS6KA4 | 0.45749559 |
| 76 | CSNK2A1 | 0.45748779 |
| 77 | CDK1 | 0.45136972 |
| 78 | STK24 | 0.44550397 |
| 79 | BRAF | 0.43675906 |
| 80 | CSNK1A1L | 0.43101944 |
| 81 | BRD4 | 0.41005529 |
| 82 | CDK2 | 0.39573478 |
| 83 | CAMK1G | 0.39470474 |
| 84 | LATS2 | 0.38612482 |
| 85 | MAP3K9 | 0.37497676 |
| 86 | MELK | 0.36612282 |
| 87 | AURKA | 0.35272466 |
| 88 | CSNK1A1 | 0.34280263 |
| 89 | INSRR | 0.33503634 |
| 90 | MAP4K2 | 0.29124747 |
| 91 | OBSCN | 0.29082151 |
| 92 | MAP3K4 | 0.27552038 |
| 93 | BCR | 0.27185103 |
| 94 | FLT3 | 0.26146531 |
| 95 | PRKCE | 0.25795905 |
| 96 | SGK494 | 0.24486537 |
| 97 | SGK223 | 0.24486537 |
| 98 | PAK4 | 0.22776145 |
| 99 | MAP2K7 | 0.22368557 |
| 100 | EGFR | 0.22301280 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mismatch repair_Homo sapiens_hsa03430 | 3.59581429 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 3.39212559 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.29837060 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.17888489 |
| 5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.03042446 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.87441035 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.80829101 |
| 8 | RNA transport_Homo sapiens_hsa03013 | 2.26737452 |
| 9 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 2.11831894 |
| 10 | Spliceosome_Homo sapiens_hsa03040 | 2.04176015 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 1.99777441 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 1.99677987 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 1.98761392 |
| 14 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.92436945 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.90890220 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.90548684 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.82926003 |
| 18 | Cell cycle_Homo sapiens_hsa04110 | 1.80291880 |
| 19 | Base excision repair_Homo sapiens_hsa03410 | 1.78468644 |
| 20 | Protein export_Homo sapiens_hsa03060 | 1.75473045 |
| 21 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.73120850 |
| 22 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.71562551 |
| 23 | Parkinsons disease_Homo sapiens_hsa05012 | 1.69162306 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.68115823 |
| 25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.67028123 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.66360800 |
| 27 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.66341188 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.57025053 |
| 29 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.47970789 |
| 30 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.44998003 |
| 31 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.37463375 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.35727592 |
| 33 | Huntingtons disease_Homo sapiens_hsa05016 | 1.35423129 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35252810 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.35233756 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.26984447 |
| 37 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.24417495 |
| 38 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.20374156 |
| 39 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.16368656 |
| 40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.12698134 |
| 41 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.07967748 |
| 42 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.04701673 |
| 43 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.01274798 |
| 44 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.98352815 |
| 45 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.95789592 |
| 46 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.93261820 |
| 47 | Alzheimers disease_Homo sapiens_hsa05010 | 0.92135072 |
| 48 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.92086069 |
| 49 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86259658 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84797546 |
| 51 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.83119242 |
| 52 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82334886 |
| 53 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.81542080 |
| 54 | Carbon metabolism_Homo sapiens_hsa01200 | 0.78642425 |
| 55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.73039176 |
| 56 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.71770396 |
| 57 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.71189778 |
| 58 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71025505 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.70402211 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66790910 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63950901 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.63445814 |
| 63 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.62845918 |
| 64 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.61972414 |
| 65 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.61856198 |
| 66 | Nicotine addiction_Homo sapiens_hsa05033 | 0.60670219 |
| 67 | Phototransduction_Homo sapiens_hsa04744 | 0.60581431 |
| 68 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.58991139 |
| 69 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.58903388 |
| 70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57441196 |
| 71 | Tight junction_Homo sapiens_hsa04530 | 0.56642116 |
| 72 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.56626531 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.55294449 |
| 74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.54291541 |
| 75 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.53396229 |
| 76 | Alcoholism_Homo sapiens_hsa05034 | 0.52783739 |
| 77 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.52623535 |
| 78 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52076396 |
| 79 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.51815763 |
| 80 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.51724689 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50934938 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.50615549 |
| 83 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.49089472 |
| 84 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46376777 |
| 85 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.45582396 |
| 86 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45489234 |
| 87 | Lysine degradation_Homo sapiens_hsa00310 | 0.44147331 |
| 88 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.43567070 |
| 89 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.41884660 |
| 90 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.41099141 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.36734249 |
| 92 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.35073358 |
| 93 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.34740757 |
| 94 | Adherens junction_Homo sapiens_hsa04520 | 0.32095035 |
| 95 | Thyroid cancer_Homo sapiens_hsa05216 | 0.31292862 |
| 96 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.29504543 |
| 97 | Gap junction_Homo sapiens_hsa04540 | 0.29088555 |
| 98 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.28897756 |
| 99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.28324628 |
| 100 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.26192843 |

