

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | telomere maintenance via semi-conservative replication (GO:0032201) | 5.25599450 |
| 2 | pyrimidine nucleotide catabolic process (GO:0006244) | 5.13481458 |
| 3 | DNA double-strand break processing (GO:0000729) | 5.02229453 |
| 4 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.92171352 |
| 5 | DNA replication checkpoint (GO:0000076) | 4.84239324 |
| 6 | telomere maintenance via recombination (GO:0000722) | 4.72111986 |
| 7 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 4.70390105 |
| 8 | DNA strand elongation (GO:0022616) | 4.60749530 |
| 9 | chromatin remodeling at centromere (GO:0031055) | 4.39890483 |
| 10 | mitotic recombination (GO:0006312) | 4.38652746 |
| 11 | CENP-A containing nucleosome assembly (GO:0034080) | 4.32694258 |
| 12 | dopamine transport (GO:0015872) | 4.20051151 |
| 13 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.91583669 |
| 14 | histone exchange (GO:0043486) | 3.90795962 |
| 15 | viral mRNA export from host cell nucleus (GO:0046784) | 3.88842935 |
| 16 | DNA ligation (GO:0006266) | 3.87654335 |
| 17 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.83836050 |
| 18 | sequestering of actin monomers (GO:0042989) | 3.81508355 |
| 19 | establishment of viral latency (GO:0019043) | 3.79759374 |
| 20 | establishment of integrated proviral latency (GO:0075713) | 3.79191842 |
| 21 | replication fork processing (GO:0031297) | 3.76588476 |
| 22 | cysteine metabolic process (GO:0006534) | 3.74037516 |
| 23 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.71157411 |
| 24 | response to misfolded protein (GO:0051788) | 3.70323144 |
| 25 | somite rostral/caudal axis specification (GO:0032525) | 3.68832560 |
| 26 | nucleoside diphosphate catabolic process (GO:0009134) | 3.67841960 |
| 27 | positive thymic T cell selection (GO:0045059) | 3.66597009 |
| 28 | DNA strand renaturation (GO:0000733) | 3.66013585 |
| 29 | translesion synthesis (GO:0019985) | 3.65439439 |
| 30 | telomere maintenance via telomere lengthening (GO:0010833) | 3.65356250 |
| 31 | mismatch repair (GO:0006298) | 3.64806861 |
| 32 | synapsis (GO:0007129) | 3.63470119 |
| 33 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.62542605 |
| 34 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.62542605 |
| 35 | postreplication repair (GO:0006301) | 3.60178486 |
| 36 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.58151700 |
| 37 | protein-cofactor linkage (GO:0018065) | 3.55669764 |
| 38 | regulation of mesoderm development (GO:2000380) | 3.54298751 |
| 39 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.50363364 |
| 40 | DNA synthesis involved in DNA repair (GO:0000731) | 3.50128622 |
| 41 | synaptonemal complex assembly (GO:0007130) | 3.43319232 |
| 42 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.41086217 |
| 43 | meiosis I (GO:0007127) | 3.39352265 |
| 44 | chromosome organization involved in meiosis (GO:0070192) | 3.38361225 |
| 45 | reciprocal meiotic recombination (GO:0007131) | 3.34561071 |
| 46 | reciprocal DNA recombination (GO:0035825) | 3.34561071 |
| 47 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.30090433 |
| 48 | cytochrome complex assembly (GO:0017004) | 3.27455639 |
| 49 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 3.24066122 |
| 50 | positive T cell selection (GO:0043368) | 3.19231393 |
| 51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.16968646 |
| 52 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.16733521 |
| 53 | UMP biosynthetic process (GO:0006222) | 3.16733521 |
| 54 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.16733521 |
| 55 | UMP metabolic process (GO:0046049) | 3.16733521 |
| 56 | synaptonemal complex organization (GO:0070193) | 3.15860497 |
| 57 | DNA biosynthetic process (GO:0071897) | 3.15496245 |
| 58 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.13529851 |
| 59 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.13464640 |
| 60 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.13464640 |
| 61 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.13464640 |
| 62 | pyrimidine ribonucleotide metabolic process (GO:0009218) | 3.12196624 |
| 63 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.12154155 |
| 64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.12154155 |
| 65 | recombinational repair (GO:0000725) | 3.11997558 |
| 66 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.10022419 |
| 67 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.08982466 |
| 68 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.08474193 |
| 69 | DNA replication-independent nucleosome organization (GO:0034724) | 3.08474193 |
| 70 | endothelial tube morphogenesis (GO:0061154) | 3.07141036 |
| 71 | morphogenesis of an endothelium (GO:0003159) | 3.07141036 |
| 72 | proteasome assembly (GO:0043248) | 3.04594590 |
| 73 | telomere maintenance (GO:0000723) | 3.04049875 |
| 74 | catecholamine transport (GO:0051937) | 3.03272041 |
| 75 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.02845307 |
| 76 | DNA recombination (GO:0006310) | 3.02718158 |
| 77 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 3.02560120 |
| 78 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.00558734 |
| 79 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.00558734 |
| 80 | protein complex biogenesis (GO:0070271) | 3.00328498 |
| 81 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.98885154 |
| 82 | DNA damage response, detection of DNA damage (GO:0042769) | 2.98084007 |
| 83 | base-excision repair (GO:0006284) | 2.96921356 |
| 84 | telomere organization (GO:0032200) | 2.96300113 |
| 85 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.95558144 |
| 86 | regulation of meiosis I (GO:0060631) | 2.89586381 |
| 87 | double-strand break repair via homologous recombination (GO:0000724) | 2.87344726 |
| 88 | piRNA metabolic process (GO:0034587) | 2.86500131 |
| 89 | respiratory chain complex IV assembly (GO:0008535) | 2.86049590 |
| 90 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.85009645 |
| 91 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.85009645 |
| 92 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.84479277 |
| 93 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.82715487 |
| 94 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.82197063 |
| 95 | negative regulation of ligase activity (GO:0051352) | 2.81867680 |
| 96 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.81867680 |
| 97 | resolution of meiotic recombination intermediates (GO:0000712) | 2.80951967 |
| 98 | positive regulation of meiotic cell cycle (GO:0051446) | 2.79884492 |
| 99 | negative T cell selection (GO:0043383) | 2.79486122 |
| 100 | serine family amino acid biosynthetic process (GO:0009070) | 2.78451170 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.37278015 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.96500477 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.68172805 |
| 4 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.39669163 |
| 5 | IRF1_19129219_ChIP-ChIP_H3396_Human | 3.37710278 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.35556908 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.79390695 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.69406605 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.68122241 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.62183948 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.51061345 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.41127079 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.35484749 |
| 14 | EWS_26573619_Chip-Seq_HEK293_Human | 2.32271565 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.19374653 |
| 16 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.11961591 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.04438354 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.00682831 |
| 19 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.97869045 |
| 20 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.95227893 |
| 21 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.91262651 |
| 22 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.87644325 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.85649261 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.72063288 |
| 25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.72057819 |
| 26 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.70942850 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.69558028 |
| 28 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.67448383 |
| 29 | FUS_26573619_Chip-Seq_HEK293_Human | 1.67007471 |
| 30 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.63473973 |
| 31 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.58385258 |
| 32 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.57739964 |
| 33 | P300_19829295_ChIP-Seq_ESCs_Human | 1.57517791 |
| 34 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.56948808 |
| 35 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.54414041 |
| 36 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.53756753 |
| 37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.53675132 |
| 38 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.53375511 |
| 39 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.50489569 |
| 40 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.45981448 |
| 41 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.45350413 |
| 42 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.42694134 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.39840724 |
| 44 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.38134979 |
| 45 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.37963182 |
| 46 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.35475448 |
| 47 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.31028186 |
| 48 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.31028186 |
| 49 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30331321 |
| 50 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.29813844 |
| 51 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.26098726 |
| 52 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.25907567 |
| 53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.25325421 |
| 54 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.24038324 |
| 55 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.23691561 |
| 56 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.22435259 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.21021617 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.19754296 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18923050 |
| 60 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.17861309 |
| 61 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.17560348 |
| 62 | NCOR_22424771_ChIP-Seq_293T_Human | 1.15977534 |
| 63 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.15501821 |
| 64 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.14526877 |
| 65 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.13376170 |
| 66 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.12870427 |
| 67 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.10759739 |
| 68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.10296716 |
| 69 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08771050 |
| 70 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08771050 |
| 71 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.07432419 |
| 72 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.06912772 |
| 73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.06459525 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.05936984 |
| 75 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.05772512 |
| 76 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.04396700 |
| 77 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03876712 |
| 78 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03815358 |
| 79 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02500544 |
| 80 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 1.02090673 |
| 81 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.02086994 |
| 82 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.00842787 |
| 83 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.99166758 |
| 84 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.98183927 |
| 85 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96851286 |
| 86 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.96654914 |
| 87 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.96645722 |
| 88 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.96215050 |
| 89 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.95717348 |
| 90 | AR_25329375_ChIP-Seq_VCAP_Human | 0.94249260 |
| 91 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.93788154 |
| 92 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.93681976 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.92257151 |
| 94 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.92000277 |
| 95 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.91496870 |
| 96 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.90927024 |
| 97 | STAT3_23295773_ChIP-Seq_U87_Human | 0.90885349 |
| 98 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.89866306 |
| 99 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.88400052 |
| 100 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.88211835 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 4.46328169 |
| 2 | MP0003123_paternal_imprinting | 3.59622923 |
| 3 | MP0003787_abnormal_imprinting | 3.52798832 |
| 4 | MP0010094_abnormal_chromosome_stability | 3.49317357 |
| 5 | MP0003890_abnormal_embryonic-extraembry | 3.24480594 |
| 6 | MP0002102_abnormal_ear_morphology | 2.96078076 |
| 7 | MP0003283_abnormal_digestive_organ | 2.83727461 |
| 8 | MP0000372_irregular_coat_pigmentation | 2.46916519 |
| 9 | MP0002163_abnormal_gland_morphology | 2.35082713 |
| 10 | MP0001529_abnormal_vocalization | 2.31433877 |
| 11 | MP0003878_abnormal_ear_physiology | 2.19172339 |
| 12 | MP0005377_hearing/vestibular/ear_phenot | 2.19172339 |
| 13 | MP0010386_abnormal_urinary_bladder | 2.17398849 |
| 14 | MP0000427_abnormal_hair_cycle | 2.10640172 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.09340892 |
| 16 | MP0008057_abnormal_DNA_replication | 2.02420258 |
| 17 | MP0003111_abnormal_nucleus_morphology | 2.01293756 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.93868676 |
| 19 | MP0001764_abnormal_homeostasis | 1.91549774 |
| 20 | MP0004133_heterotaxia | 1.83736473 |
| 21 | MP0002736_abnormal_nociception_after | 1.82794988 |
| 22 | MP0005171_absent_coat_pigmentation | 1.74842198 |
| 23 | MP0003183_abnormal_peptide_metabolism | 1.74385939 |
| 24 | MP0006292_abnormal_olfactory_placode | 1.68810634 |
| 25 | MP0004957_abnormal_blastocyst_morpholog | 1.64247474 |
| 26 | MP0009697_abnormal_copulation | 1.63918831 |
| 27 | MP0008872_abnormal_physiological_respon | 1.62375797 |
| 28 | MP0003121_genomic_imprinting | 1.59703160 |
| 29 | MP0005379_endocrine/exocrine_gland_phen | 1.58026863 |
| 30 | MP0002210_abnormal_sex_determination | 1.48749181 |
| 31 | MP0001929_abnormal_gametogenesis | 1.47919108 |
| 32 | MP0003119_abnormal_digestive_system | 1.46532037 |
| 33 | MP0000569_abnormal_digit_pigmentation | 1.46274256 |
| 34 | MP0006072_abnormal_retinal_apoptosis | 1.44706443 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.42821366 |
| 36 | MP0000490_abnormal_crypts_of | 1.42005393 |
| 37 | MP0002837_dystrophic_cardiac_calcinosis | 1.41417796 |
| 38 | MP0003786_premature_aging | 1.32861603 |
| 39 | MP0001119_abnormal_female_reproductive | 1.32826882 |
| 40 | MP0001145_abnormal_male_reproductive | 1.31661218 |
| 41 | MP0005645_abnormal_hypothalamus_physiol | 1.30360929 |
| 42 | MP0000653_abnormal_sex_gland | 1.27792036 |
| 43 | MP0001485_abnormal_pinna_reflex | 1.27192787 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.25768348 |
| 45 | MP0004147_increased_porphyrin_level | 1.24794765 |
| 46 | MP0003136_yellow_coat_color | 1.22784650 |
| 47 | MP0003567_abnormal_fetal_cardiomyocyte | 1.18636836 |
| 48 | MP0002160_abnormal_reproductive_system | 1.18437469 |
| 49 | MP0006054_spinal_hemorrhage | 1.18332556 |
| 50 | MP0004742_abnormal_vestibular_system | 1.15745895 |
| 51 | MP0008932_abnormal_embryonic_tissue | 1.15251451 |
| 52 | MP0005389_reproductive_system_phenotype | 1.15234396 |
| 53 | MP0000613_abnormal_salivary_gland | 1.13122400 |
| 54 | MP0000631_abnormal_neuroendocrine_gland | 1.11919255 |
| 55 | MP0001293_anophthalmia | 1.11325977 |
| 56 | MP0001963_abnormal_hearing_physiology | 1.11131932 |
| 57 | MP0003195_calcinosis | 1.10637113 |
| 58 | MP0000647_abnormal_sebaceous_gland | 1.10369080 |
| 59 | MP0000026_abnormal_inner_ear | 1.08504164 |
| 60 | MP0005671_abnormal_response_to | 1.07420085 |
| 61 | MP0003950_abnormal_plasma_membrane | 1.07247844 |
| 62 | MP0008995_early_reproductive_senescence | 1.05510533 |
| 63 | MP0005310_abnormal_salivary_gland | 1.05506922 |
| 64 | MP0000538_abnormal_urinary_bladder | 1.04857311 |
| 65 | MP0008004_abnormal_stomach_pH | 1.03920455 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 1.02868361 |
| 67 | MP0002751_abnormal_autonomic_nervous | 1.02506680 |
| 68 | MP0002938_white_spotting | 1.02077059 |
| 69 | MP0005253_abnormal_eye_physiology | 1.01965649 |
| 70 | MP0002933_joint_inflammation | 0.97715708 |
| 71 | MP0003941_abnormal_skin_development | 0.96922209 |
| 72 | MP0003137_abnormal_impulse_conducting | 0.95769315 |
| 73 | MP0003698_abnormal_male_reproductive | 0.95641657 |
| 74 | MP0004215_abnormal_myocardial_fiber | 0.92948672 |
| 75 | MP0010368_abnormal_lymphatic_system | 0.92702767 |
| 76 | MP0002735_abnormal_chemical_nociception | 0.90636789 |
| 77 | MP0005220_abnormal_exocrine_pancreas | 0.90458266 |
| 78 | MP0005408_hypopigmentation | 0.88523335 |
| 79 | MP0001919_abnormal_reproductive_system | 0.86362654 |
| 80 | MP0000383_abnormal_hair_follicle | 0.85611738 |
| 81 | MP0002009_preneoplasia | 0.85447703 |
| 82 | MP0003077_abnormal_cell_cycle | 0.84427334 |
| 83 | MP0008007_abnormal_cellular_replicative | 0.81233456 |
| 84 | MP0004019_abnormal_vitamin_homeostasis | 0.78894682 |
| 85 | MP0000462_abnormal_digestive_system | 0.78756548 |
| 86 | MP0003699_abnormal_female_reproductive | 0.77838977 |
| 87 | MP0000049_abnormal_middle_ear | 0.77035135 |
| 88 | MP0005332_abnormal_amino_acid | 0.76721131 |
| 89 | MP0004145_abnormal_muscle_electrophysio | 0.76613080 |
| 90 | MP0003936_abnormal_reproductive_system | 0.76276938 |
| 91 | MP0000516_abnormal_urinary_system | 0.71312186 |
| 92 | MP0005367_renal/urinary_system_phenotyp | 0.71312186 |
| 93 | MP0003937_abnormal_limbs/digits/tail_de | 0.68126361 |
| 94 | MP0003880_abnormal_central_pattern | 0.65329211 |
| 95 | MP0003866_abnormal_defecation | 0.62786553 |
| 96 | MP0005187_abnormal_penis_morphology | 0.60279240 |
| 97 | MP0001286_abnormal_eye_development | 0.60020429 |
| 98 | MP0004924_abnormal_behavior | 0.59597530 |
| 99 | MP0005386_behavior/neurological_phenoty | 0.59597530 |
| 100 | MP0001486_abnormal_startle_reflex | 0.58417027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type II lissencephaly (HP:0007260) | 6.16651539 |
| 2 | Intestinal atresia (HP:0011100) | 5.30348107 |
| 3 | Retinal dysplasia (HP:0007973) | 4.33286970 |
| 4 | Oligodactyly (hands) (HP:0001180) | 4.28167909 |
| 5 | Carpal bone hypoplasia (HP:0001498) | 3.89162866 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.75033941 |
| 7 | Severe combined immunodeficiency (HP:0004430) | 3.69709086 |
| 8 | Abnormality of the parathyroid morphology (HP:0011766) | 3.65852947 |
| 9 | Cerebellar dysplasia (HP:0007033) | 3.58379175 |
| 10 | Congenital stationary night blindness (HP:0007642) | 3.57790440 |
| 11 | Gonadotropin excess (HP:0000837) | 3.46133141 |
| 12 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.30560973 |
| 13 | Combined immunodeficiency (HP:0005387) | 3.25262058 |
| 14 | 3-Methylglutaconic aciduria (HP:0003535) | 3.12466449 |
| 15 | Anterior segment dysgenesis (HP:0007700) | 3.09827838 |
| 16 | Colon cancer (HP:0003003) | 3.08310295 |
| 17 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.94886280 |
| 18 | Oligodactyly (HP:0012165) | 2.92815533 |
| 19 | Hypothermia (HP:0002045) | 2.92024294 |
| 20 | Esophageal atresia (HP:0002032) | 2.91215165 |
| 21 | Gastrointestinal atresia (HP:0002589) | 2.88805701 |
| 22 | Acute necrotizing encephalopathy (HP:0006965) | 2.74181260 |
| 23 | Aqueductal stenosis (HP:0002410) | 2.71735218 |
| 24 | Amelogenesis imperfecta (HP:0000705) | 2.65604090 |
| 25 | Aplasia involving forearm bones (HP:0009822) | 2.64301954 |
| 26 | Absent forearm bone (HP:0003953) | 2.64301954 |
| 27 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.58085445 |
| 28 | Panhypogammaglobulinemia (HP:0003139) | 2.56940154 |
| 29 | Absent radius (HP:0003974) | 2.53877422 |
| 30 | Lissencephaly (HP:0001339) | 2.51567868 |
| 31 | Pancreatic cysts (HP:0001737) | 2.49984857 |
| 32 | Abnormality of the duodenum (HP:0002246) | 2.49758087 |
| 33 | Dandy-Walker malformation (HP:0001305) | 2.43357219 |
| 34 | Mitochondrial inheritance (HP:0001427) | 2.42467160 |
| 35 | Thyroiditis (HP:0100646) | 2.41695429 |
| 36 | Biliary tract neoplasm (HP:0100574) | 2.40558641 |
| 37 | Volvulus (HP:0002580) | 2.37876978 |
| 38 | Small intestinal stenosis (HP:0012848) | 2.37553855 |
| 39 | Duodenal stenosis (HP:0100867) | 2.37553855 |
| 40 | Abnormality of the ileum (HP:0001549) | 2.36608197 |
| 41 | Increased CSF lactate (HP:0002490) | 2.36287299 |
| 42 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.34461074 |
| 43 | Hypoplasia of the fovea (HP:0007750) | 2.32393417 |
| 44 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.32393417 |
| 45 | Chin dimple (HP:0010751) | 2.29427910 |
| 46 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.29269226 |
| 47 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.27059891 |
| 48 | Anencephaly (HP:0002323) | 2.24030845 |
| 49 | Hepatocellular necrosis (HP:0001404) | 2.20311053 |
| 50 | Abnormality of chromosome stability (HP:0003220) | 2.19723641 |
| 51 | Progressive macrocephaly (HP:0004481) | 2.18579172 |
| 52 | Meckel diverticulum (HP:0002245) | 2.18510888 |
| 53 | Optic nerve hypoplasia (HP:0000609) | 2.17799994 |
| 54 | Occipital encephalocele (HP:0002085) | 2.16819565 |
| 55 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.14835120 |
| 56 | Abnormal lung lobation (HP:0002101) | 2.13975854 |
| 57 | Hepatic necrosis (HP:0002605) | 2.13541648 |
| 58 | Bilateral microphthalmos (HP:0007633) | 2.13174212 |
| 59 | Irregular epiphyses (HP:0010582) | 2.12069702 |
| 60 | Triphalangeal thumb (HP:0001199) | 2.10746503 |
| 61 | Abnormal biliary tract physiology (HP:0012439) | 2.09714326 |
| 62 | Bile duct proliferation (HP:0001408) | 2.09714326 |
| 63 | Acute encephalopathy (HP:0006846) | 2.08974009 |
| 64 | Supernumerary spleens (HP:0009799) | 2.07506652 |
| 65 | True hermaphroditism (HP:0010459) | 2.07398736 |
| 66 | Abnormality of the fovea (HP:0000493) | 2.06019679 |
| 67 | Patellar aplasia (HP:0006443) | 2.05491623 |
| 68 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.03473406 |
| 69 | Broad ribs (HP:0000885) | 2.02997044 |
| 70 | Intellectual disability, profound (HP:0002187) | 2.02035127 |
| 71 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.02001151 |
| 72 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.00819341 |
| 73 | Abnormality of the labia minora (HP:0012880) | 1.99787844 |
| 74 | Ankle clonus (HP:0011448) | 1.99704258 |
| 75 | Double outlet right ventricle (HP:0001719) | 1.98864444 |
| 76 | Congenital malformation of the right heart (HP:0011723) | 1.98864444 |
| 77 | Non-midline cleft lip (HP:0100335) | 1.97983138 |
| 78 | Hypoproteinemia (HP:0003075) | 1.97000393 |
| 79 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.96789378 |
| 80 | Mixed hearing impairment (HP:0000410) | 1.96415392 |
| 81 | Megaloblastic anemia (HP:0001889) | 1.93032820 |
| 82 | Hypoplasia of the ulna (HP:0003022) | 1.91325921 |
| 83 | Chorioretinal coloboma (HP:0000567) | 1.90988259 |
| 84 | Neoplasm of the colon (HP:0100273) | 1.90891126 |
| 85 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.90797325 |
| 86 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.90316812 |
| 87 | Nuclear cataract (HP:0100018) | 1.89662128 |
| 88 | Ectopic kidney (HP:0000086) | 1.89221403 |
| 89 | Cerebral edema (HP:0002181) | 1.87445368 |
| 90 | Hypoplastic pelvis (HP:0008839) | 1.87119388 |
| 91 | Preaxial hand polydactyly (HP:0001177) | 1.86234010 |
| 92 | Abnormality of chromosome segregation (HP:0002916) | 1.83702583 |
| 93 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.82498787 |
| 94 | Absent epiphyses (HP:0010577) | 1.82498787 |
| 95 | Fair hair (HP:0002286) | 1.82216184 |
| 96 | Impaired proprioception (HP:0010831) | 1.81211460 |
| 97 | Anophthalmia (HP:0000528) | 1.80916313 |
| 98 | Neoplasm of the small intestine (HP:0100833) | 1.80509773 |
| 99 | Tinnitus (HP:0000360) | 1.80005547 |
| 100 | Rhabdomyosarcoma (HP:0002859) | 1.79975663 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.83554199 |
| 2 | PLK4 | 3.46081281 |
| 3 | FRK | 3.28711768 |
| 4 | VRK1 | 3.11152377 |
| 5 | ERBB4 | 2.78645975 |
| 6 | WEE1 | 2.54041330 |
| 7 | KDR | 2.22627530 |
| 8 | NUAK1 | 2.05470297 |
| 9 | CDC7 | 1.86172710 |
| 10 | BUB1 | 1.86075938 |
| 11 | BRSK2 | 1.82944126 |
| 12 | ADRBK2 | 1.74511341 |
| 13 | BMPR1B | 1.73207059 |
| 14 | TAF1 | 1.71720666 |
| 15 | WNK3 | 1.65091439 |
| 16 | GRK1 | 1.63242945 |
| 17 | ACVR1B | 1.60562637 |
| 18 | PLK3 | 1.59059589 |
| 19 | ERBB3 | 1.58541722 |
| 20 | DMPK | 1.57398876 |
| 21 | MST4 | 1.57119227 |
| 22 | BRSK1 | 1.53722470 |
| 23 | MELK | 1.53599679 |
| 24 | MAP3K4 | 1.51594555 |
| 25 | MYLK | 1.50845535 |
| 26 | ZAK | 1.49707666 |
| 27 | NLK | 1.47718765 |
| 28 | CAMKK2 | 1.44105677 |
| 29 | GRK5 | 1.35736476 |
| 30 | CSNK1G1 | 1.34853684 |
| 31 | WNK4 | 1.32661860 |
| 32 | BCR | 1.31334856 |
| 33 | MKNK1 | 1.31111760 |
| 34 | CSNK1G3 | 1.29962744 |
| 35 | CSNK1A1L | 1.27228738 |
| 36 | PLK2 | 1.19457534 |
| 37 | SRPK1 | 1.18973844 |
| 38 | TNIK | 1.18573114 |
| 39 | CSNK1G2 | 1.15172020 |
| 40 | EIF2AK3 | 1.14811260 |
| 41 | MAP2K7 | 1.14797309 |
| 42 | TSSK6 | 1.14196431 |
| 43 | ADRBK1 | 1.10562215 |
| 44 | MAPK13 | 1.08612881 |
| 45 | EIF2AK1 | 0.93001101 |
| 46 | TIE1 | 0.92874447 |
| 47 | TLK1 | 0.92670168 |
| 48 | IRAK2 | 0.92034127 |
| 49 | YES1 | 0.90458346 |
| 50 | PLK1 | 0.90068341 |
| 51 | BMX | 0.88761624 |
| 52 | TXK | 0.86883629 |
| 53 | ATR | 0.86385201 |
| 54 | MKNK2 | 0.83609100 |
| 55 | PASK | 0.83546251 |
| 56 | INSRR | 0.83188538 |
| 57 | TTK | 0.83142300 |
| 58 | CHEK2 | 0.83091728 |
| 59 | TGFBR1 | 0.76080026 |
| 60 | UHMK1 | 0.75335138 |
| 61 | CDK3 | 0.68190194 |
| 62 | AURKB | 0.67462658 |
| 63 | EIF2AK2 | 0.67449687 |
| 64 | MAP3K6 | 0.66222092 |
| 65 | CDK7 | 0.60983230 |
| 66 | CSNK1A1 | 0.60150374 |
| 67 | IRAK1 | 0.56370861 |
| 68 | MARK3 | 0.56285013 |
| 69 | STK16 | 0.55886820 |
| 70 | WNK1 | 0.55434823 |
| 71 | GRK6 | 0.54318781 |
| 72 | MAPK15 | 0.51709498 |
| 73 | TGFBR2 | 0.50453356 |
| 74 | ATM | 0.47751156 |
| 75 | PTK2B | 0.46478435 |
| 76 | GRK7 | 0.45865258 |
| 77 | TESK2 | 0.44835658 |
| 78 | OBSCN | 0.43954638 |
| 79 | TRIM28 | 0.42636988 |
| 80 | STK38L | 0.41518300 |
| 81 | CDK18 | 0.40124277 |
| 82 | CAMKK1 | 0.39614135 |
| 83 | FGR | 0.38628691 |
| 84 | CDK15 | 0.38584280 |
| 85 | FGFR2 | 0.38047663 |
| 86 | CSNK1D | 0.37545681 |
| 87 | CSNK2A1 | 0.36416258 |
| 88 | LIMK1 | 0.36367387 |
| 89 | CDK14 | 0.36358970 |
| 90 | SIK2 | 0.36099483 |
| 91 | PRKCQ | 0.35465804 |
| 92 | TAOK3 | 0.35053956 |
| 93 | GSK3A | 0.33469246 |
| 94 | DDR2 | 0.33228373 |
| 95 | STK11 | 0.32811484 |
| 96 | DYRK1B | 0.28255705 |
| 97 | PRKCG | 0.27572661 |
| 98 | CDK11A | 0.26444603 |
| 99 | NEK6 | 0.25954067 |
| 100 | PRKACA | 0.23838172 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mismatch repair_Homo sapiens_hsa03430 | 5.42222937 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 4.38597584 |
| 3 | Homologous recombination_Homo sapiens_hsa03440 | 4.36667793 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 4.10089858 |
| 5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.32980163 |
| 6 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.11470456 |
| 7 | Base excision repair_Homo sapiens_hsa03410 | 2.69158080 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.49614454 |
| 9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.41963006 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.33140855 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.31687062 |
| 12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.04434744 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.03886381 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.93347037 |
| 15 | Asthma_Homo sapiens_hsa05310 | 1.52082267 |
| 16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.51726968 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.42990699 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.42218935 |
| 19 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.36453851 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.36405683 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.32812093 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.31435848 |
| 23 | Purine metabolism_Homo sapiens_hsa00230 | 1.28007473 |
| 24 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.27434194 |
| 25 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.25061992 |
| 26 | Allograft rejection_Homo sapiens_hsa05330 | 1.23619572 |
| 27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.23095884 |
| 28 | Cell cycle_Homo sapiens_hsa04110 | 1.18338000 |
| 29 | RNA transport_Homo sapiens_hsa03013 | 1.17868894 |
| 30 | Spliceosome_Homo sapiens_hsa03040 | 1.13837470 |
| 31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.11394701 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.09565327 |
| 33 | RNA polymerase_Homo sapiens_hsa03020 | 1.09348643 |
| 34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.08379779 |
| 35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.03162918 |
| 36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.00667090 |
| 37 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.95314646 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.94807623 |
| 39 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.94602582 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94493967 |
| 41 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.92196948 |
| 42 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.86889155 |
| 43 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.83815370 |
| 44 | Alzheimers disease_Homo sapiens_hsa05010 | 0.82474708 |
| 45 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.81373312 |
| 46 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.79213910 |
| 47 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.76672316 |
| 48 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.74398355 |
| 49 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.72938335 |
| 50 | Taste transduction_Homo sapiens_hsa04742 | 0.71602544 |
| 51 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.70681803 |
| 52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.69885495 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.68020613 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.67660587 |
| 55 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.66131837 |
| 56 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65991359 |
| 57 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.65841454 |
| 58 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.62756597 |
| 59 | Ribosome_Homo sapiens_hsa03010 | 0.60579144 |
| 60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60519995 |
| 61 | ABC transporters_Homo sapiens_hsa02010 | 0.57656330 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.55468819 |
| 63 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.53576857 |
| 64 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53340445 |
| 65 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.50977346 |
| 66 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.50200009 |
| 67 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.49408332 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48752443 |
| 69 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.45024573 |
| 70 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.44820436 |
| 71 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.42545652 |
| 72 | Renin secretion_Homo sapiens_hsa04924 | 0.40437187 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39154785 |
| 74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.38440441 |
| 75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37217387 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.34852257 |
| 77 | HTLV-I infection_Homo sapiens_hsa05166 | 0.34845411 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.34666670 |
| 79 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.34575241 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33477583 |
| 81 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33044524 |
| 82 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.32870666 |
| 83 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.32713184 |
| 84 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.32472473 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.30178829 |
| 86 | Histidine metabolism_Homo sapiens_hsa00340 | 0.28234828 |
| 87 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.26858556 |
| 88 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.24737360 |
| 89 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.23281365 |
| 90 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.23257535 |
| 91 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.22654934 |
| 92 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.22425559 |
| 93 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.21102881 |
| 94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.20235325 |
| 95 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.19070269 |
| 96 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.18873173 |
| 97 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.18449833 |
| 98 | Phagosome_Homo sapiens_hsa04145 | 0.17494940 |
| 99 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.15584585 |
| 100 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.15154155 |

