ANKRD24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-amino acid import (GO:0043092)5.35669530
2positive regulation of synapse maturation (GO:0090129)5.20532672
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.02389584
4amino acid import (GO:0043090)4.86099491
5cerebellar granule cell differentiation (GO:0021707)4.61461229
6regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.60579584
7synaptic vesicle docking involved in exocytosis (GO:0016081)4.47899281
8positive regulation of dendritic spine development (GO:0060999)4.46542104
9regulation of synaptic plasticity (GO:0048167)4.32689463
10synaptic vesicle maturation (GO:0016188)4.31721606
11positive regulation of dendritic spine morphogenesis (GO:0061003)4.31362067
12regulation of synapse structural plasticity (GO:0051823)4.28488975
13locomotory exploration behavior (GO:0035641)4.23726265
14positive regulation of neurotransmitter transport (GO:0051590)4.14488038
15regulation of synapse maturation (GO:0090128)4.14059656
16regulation of neurotransmitter levels (GO:0001505)4.11920667
17regulation of ARF protein signal transduction (GO:0032012)4.10907652
18embryonic camera-type eye morphogenesis (GO:0048596)4.06824053
19negative regulation of dendrite morphogenesis (GO:0050774)4.05652029
20axon ensheathment in central nervous system (GO:0032291)4.03700688
21central nervous system myelination (GO:0022010)4.03700688
22regulation of excitatory postsynaptic membrane potential (GO:0060079)4.01866148
23regulation of voltage-gated calcium channel activity (GO:1901385)4.00018424
24positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.98997702
25cytoskeletal anchoring at plasma membrane (GO:0007016)3.93819874
26chondrocyte proliferation (GO:0035988)3.88305545
27synaptic vesicle exocytosis (GO:0016079)3.88064621
28regulation of dendritic spine morphogenesis (GO:0061001)3.86603541
29negative regulation of synaptic transmission, GABAergic (GO:0032229)3.85412881
30positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.85032125
31vocalization behavior (GO:0071625)3.83599984
32positive regulation of guanylate cyclase activity (GO:0031284)3.80180621
33protein retention in ER lumen (GO:0006621)3.79778396
34neurotransmitter-gated ion channel clustering (GO:0072578)3.79412283
35regulation of neurotransmitter transport (GO:0051588)3.77932566
36G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.77392701
37layer formation in cerebral cortex (GO:0021819)3.73935479
38regulation of guanylate cyclase activity (GO:0031282)3.73782083
39dendritic spine morphogenesis (GO:0060997)3.72945493
40regulation of postsynaptic membrane potential (GO:0060078)3.71209185
41response to pheromone (GO:0019236)3.68171872
42somite development (GO:0061053)3.67180389
43positive regulation of prostaglandin secretion (GO:0032308)3.62254102
44cellular potassium ion homeostasis (GO:0030007)3.61087775
45positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.59809371
46regulation of dendritic spine development (GO:0060998)3.58918383
47regulation of synaptic vesicle exocytosis (GO:2000300)3.57777547
48regulation of vesicle fusion (GO:0031338)3.57211444
49maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.54779401
50long-term memory (GO:0007616)3.54755712
51cerebellar Purkinje cell differentiation (GO:0021702)3.50056756
52synaptic vesicle endocytosis (GO:0048488)3.45454816
53glycine transport (GO:0015816)3.43983046
54glutamate secretion (GO:0014047)3.42716509
55dendritic spine organization (GO:0097061)3.41404671
56acidic amino acid transport (GO:0015800)3.38785770
57activation of protein kinase A activity (GO:0034199)3.38640867
58auditory receptor cell differentiation (GO:0042491)3.34686226
59cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.33461309
60regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.32038745
61phosphorelay signal transduction system (GO:0000160)3.30713465
62regulation of synaptic transmission (GO:0050804)3.30237838
63positive regulation of dendrite development (GO:1900006)3.27044521
64chemosensory behavior (GO:0007635)3.24299780
65neurotransmitter secretion (GO:0007269)3.23978655
66cell migration in hindbrain (GO:0021535)3.23357366
67negative regulation of T cell differentiation in thymus (GO:0033085)3.22675497
68membrane depolarization (GO:0051899)3.21615299
69embryonic eye morphogenesis (GO:0048048)3.20135368
70regulation of glutamate receptor signaling pathway (GO:1900449)3.17448254
71gamma-aminobutyric acid signaling pathway (GO:0007214)3.17305108
72sodium ion export (GO:0071436)3.16807346
73vesicle docking involved in exocytosis (GO:0006904)3.14937218
74regulation of synaptic vesicle transport (GO:1902803)3.13284212
75dicarboxylic acid transport (GO:0006835)3.12664499
76regulation of exocytosis (GO:0017157)3.12329463
77regulation of prostaglandin secretion (GO:0032306)3.10078388
78membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.09621361
79establishment of synaptic vesicle localization (GO:0097480)3.09466788
80synaptic vesicle transport (GO:0048489)3.09466788
81potassium ion homeostasis (GO:0055075)3.09281040
82positive regulation of icosanoid secretion (GO:0032305)3.08192403
83neuromuscular process (GO:0050905)3.07591255
84neuromuscular process controlling posture (GO:0050884)3.06745109
85regulation of dendrite morphogenesis (GO:0048814)3.04276198
86L-glutamate transport (GO:0015813)3.02009798
87synaptic transmission (GO:0007268)3.00643315
88ionotropic glutamate receptor signaling pathway (GO:0035235)2.98779036
89neurotransmitter uptake (GO:0001504)2.97293151
90neuromuscular synaptic transmission (GO:0007274)2.97057859
91negative regulation of alpha-beta T cell differentiation (GO:0046639)2.95314890
92regulation of calcium ion-dependent exocytosis (GO:0017158)2.94864601
93regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.93408466
94proline transport (GO:0015824)2.92456887
95cell communication by electrical coupling (GO:0010644)2.92147237
96regulation of neuronal synaptic plasticity (GO:0048168)2.90764954
97synaptic transmission, glutamatergic (GO:0035249)2.89830480
98sulfate transmembrane transport (GO:1902358)2.89258944
99gamma-aminobutyric acid transport (GO:0015812)2.87303053
100cellular sodium ion homeostasis (GO:0006883)2.85293620
101polyketide metabolic process (GO:0030638)2.83679681
102doxorubicin metabolic process (GO:0044598)2.83679681
103daunorubicin metabolic process (GO:0044597)2.83679681
104response to auditory stimulus (GO:0010996)2.81610407
105regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.80666971
106exploration behavior (GO:0035640)2.76721785
107smooth muscle tissue development (GO:0048745)2.76545680
108positive regulation of synaptic transmission, GABAergic (GO:0032230)2.75515207
109positive regulation of fatty acid transport (GO:2000193)2.74518979
110membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.73209881
111potassium ion import (GO:0010107)2.73120427
112neuronal action potential propagation (GO:0019227)2.70357333
113righting reflex (GO:0060013)2.68618407
114cerebellar Purkinje cell layer development (GO:0021680)2.66607350
115membrane hyperpolarization (GO:0060081)2.66582023
116long term synaptic depression (GO:0060292)2.65310493
117auditory behavior (GO:0031223)2.63639740
118neurotransmitter transport (GO:0006836)2.63577290
119insulin secretion (GO:0030073)2.61954994
120neuromuscular process controlling balance (GO:0050885)2.61287088
121cell communication involved in cardiac conduction (GO:0086065)2.61145413
122neuron cell-cell adhesion (GO:0007158)2.60634389
123postsynaptic membrane organization (GO:0001941)2.60213070
124protein localization to synapse (GO:0035418)2.59810428
125glutamate receptor signaling pathway (GO:0007215)2.59117459
126cardiac conduction (GO:0061337)2.58580303
127GDP-mannose metabolic process (GO:0019673)2.57267081
128transmission of nerve impulse (GO:0019226)2.57136378
129membrane depolarization during action potential (GO:0086010)2.56847555
130striatum development (GO:0021756)2.55106735
131auditory receptor cell stereocilium organization (GO:0060088)2.54179547
132N-glycan processing (GO:0006491)2.52985335
133neuronal ion channel clustering (GO:0045161)2.52434234
134positive regulation of T cell differentiation in thymus (GO:0033089)2.52427809
135regulation of neurotransmitter secretion (GO:0046928)2.52043689
136startle response (GO:0001964)2.51390654
137regulation of long-term neuronal synaptic plasticity (GO:0048169)2.50617660
138neuron-neuron synaptic transmission (GO:0007270)2.50351906
139innervation (GO:0060384)2.47394269
140vesicle transport along microtubule (GO:0047496)2.44528947
141positive regulation of neurotransmitter secretion (GO:0001956)2.43603229
142multicellular organismal signaling (GO:0035637)2.43582330
143membrane repolarization during action potential (GO:0086011)2.42239956
144negative regulation of cytosolic calcium ion concentration (GO:0051481)2.41741936
145retinal rod cell development (GO:0046548)2.41250191
146inner ear receptor cell differentiation (GO:0060113)2.41243617
147regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.40334202
148positive regulation of membrane potential (GO:0045838)2.40046935
149G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.39240635
150detection of calcium ion (GO:0005513)2.38969613
151inner ear receptor cell development (GO:0060119)2.38026393
152retinal cone cell development (GO:0046549)2.36982950

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.19609058
2THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.26056172
3GBX2_23144817_ChIP-Seq_PC3_Human2.88293337
4* DROSHA_22980978_ChIP-Seq_HELA_Human2.61118292
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.53641320
6IKZF1_21737484_ChIP-ChIP_HCT116_Human2.52472297
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.49960018
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.45139725
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.34803830
10EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.32999670
11ERG_21242973_ChIP-ChIP_JURKAT_Human2.29769777
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.27065935
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.26450869
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.26450869
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.25965820
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.25669282
17REST_21632747_ChIP-Seq_MESCs_Mouse2.23616171
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.20794756
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.17625962
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.14267728
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.14143754
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.10950867
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.10327907
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.02681842
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.98850514
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.97006911
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.73449436
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.69502991
29STAT6_21828071_ChIP-Seq_BEAS2B_Human1.69176773
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.68631123
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.63693942
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.63262004
33* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.55055127
34ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.53756234
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46067361
36TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.42830668
37CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41497687
38RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.41212697
39BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39849680
40WT1_25993318_ChIP-Seq_PODOCYTE_Human1.39489055
41RING1B_27294783_Chip-Seq_ESCs_Mouse1.38253670
42SMC4_20622854_ChIP-Seq_HELA_Human1.37705346
43VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.37045067
44MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.35553556
45ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31661072
46* P68_20966046_ChIP-Seq_HELA_Human1.31346429
47AHR_22903824_ChIP-Seq_MCF-7_Human1.30374878
48CREB1_26743006_Chip-Seq_LNCaP_Human1.27709235
49KDM2B_26808549_Chip-Seq_DND41_Human1.27378207
50GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.26972794
51RING1B_27294783_Chip-Seq_NPCs_Mouse1.23803239
52KDM2B_26808549_Chip-Seq_K562_Human1.22089174
53SMAD4_21799915_ChIP-Seq_A2780_Human1.21529160
54SRY_22984422_ChIP-ChIP_TESTIS_Rat1.21281896
55SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.21058027
56ZNF274_21170338_ChIP-Seq_K562_Hela1.20579343
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.20405818
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.20090913
59* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.19376757
60* OCT4_19829295_ChIP-Seq_ESCs_Human1.17887203
61SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.16151689
62GATA1_26923725_Chip-Seq_HPCs_Mouse1.15570103
63ARNT_22903824_ChIP-Seq_MCF-7_Human1.15130047
64DNAJC2_21179169_ChIP-ChIP_NT2_Human1.14011467
65P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12960958
66AR_19668381_ChIP-Seq_PC3_Human1.12850136
67ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.10779876
68UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.10689991
69TET1_21451524_ChIP-Seq_MESCs_Mouse1.09410354
70PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05943762
71CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05807187
72SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.05719042
73CBX2_27304074_Chip-Seq_ESCs_Mouse1.04898028
74TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.04300090
75KLF4_19829295_ChIP-Seq_ESCs_Human1.02554020
76PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.02404526
77SMAD3_21741376_ChIP-Seq_ESCs_Human1.00621663
78PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00106950
79YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99956318
80PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.99950637
81NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.99443504
82KDM2B_26808549_Chip-Seq_JURKAT_Human0.97937007
83STAT3_23295773_ChIP-Seq_U87_Human0.97358165
84PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96813138
85CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96106894
86* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.95933420
87* DPY_21335234_ChIP-Seq_ESCs_Mouse0.95437878
88DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.95420629
89CTCF_27219007_Chip-Seq_Bcells_Human0.95379074
90EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.94258830
91RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93917752
92ELK4_26923725_Chip-Seq_MESODERM_Mouse0.93386806
93ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93229212
94ESR1_20079471_ChIP-ChIP_T-47D_Human0.93083347
95CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92573987
96KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.92408771
97* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.92205017
98SA1_27219007_Chip-Seq_ERYTHROID_Human0.91957873
99ZFP281_27345836_Chip-Seq_ESCs_Mouse0.91326609
100SMAD3_21741376_ChIP-Seq_EPCs_Human0.91031201
101* TCF7_22412390_ChIP-Seq_EML_Mouse0.90849114
102AR_25329375_ChIP-Seq_VCAP_Human0.90828143
103TCF4_23295773_ChIP-Seq_U87_Human0.90556236
104AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.89101537
105MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.88653266
106* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88526435
107SMAD3_21741376_ChIP-Seq_HESCs_Human0.88236064
108SOX2_21211035_ChIP-Seq_LN229_Gbm0.87976694
109SA1_27219007_Chip-Seq_Bcells_Human0.87923059
110ZFP281_18757296_ChIP-ChIP_E14_Mouse0.87901207
111SMAD4_21741376_ChIP-Seq_ESCs_Human0.87171834
112SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86839814
113TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.85688464
114* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.85289052
115RXR_22108803_ChIP-Seq_LS180_Human0.84721387
116TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.84564771
117TP53_20018659_ChIP-ChIP_R1E_Mouse0.84430167
118EGR1_19032775_ChIP-ChIP_M12_Human0.83525004
119OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.83007228
120TP53_23651856_ChIP-Seq_MEFs_Mouse0.82985926
121SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82313993
122GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.82009956
123NR3C1_23031785_ChIP-Seq_PC12_Mouse0.81616543
124* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81544904
125TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80945537
126POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.80945537
127SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.80931952
128FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80532429
129* RACK7_27058665_Chip-Seq_MCF-7_Human0.80415195
130MYC_19915707_ChIP-ChIP_AK7_Human0.80386523
131LXR_22292898_ChIP-Seq_THP-1_Human0.80161252
132SMAD4_21741376_ChIP-Seq_HESCs_Human0.80058012
133* SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.79983609
134TET1_21490601_ChIP-Seq_MESCs_Mouse0.79355106
135NANOG_18555785_Chip-Seq_ESCs_Mouse0.79154236
136TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.78412567
137TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.78243705
138ESR2_21235772_ChIP-Seq_MCF-7_Human0.77731075
139RNF2_27304074_Chip-Seq_NSC_Mouse0.77666740
140WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.77584132
141NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.77417533
142SOX3_22085726_ChIP-Seq_NPCs_Mouse0.77327988
143MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.76830607
144RUNX2_22187159_ChIP-Seq_PCA_Human0.76729219
145P300_19829295_ChIP-Seq_ESCs_Human0.76451130
146RUNX1_26923725_Chip-Seq_HPCs_Mouse0.76004320

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003283_abnormal_digestive_organ7.19402647
2MP0005377_hearing/vestibular/ear_phenot6.50873399
3MP0003878_abnormal_ear_physiology6.50873399
4MP0002822_catalepsy6.24550894
5MP0003879_abnormal_hair_cell3.65752737
6MP0004859_abnormal_synaptic_plasticity3.24047236
7MP0001485_abnormal_pinna_reflex3.06037894
8MP0005167_abnormal_blood-brain_barrier2.77816349
9MP0003329_amyloid_beta_deposits2.62136402
10MP0002909_abnormal_adrenal_gland2.46552591
11MP0005645_abnormal_hypothalamus_physiol2.25926435
12MP0001486_abnormal_startle_reflex2.04656164
13MP0003690_abnormal_glial_cell2.02282965
14MP0003635_abnormal_synaptic_transmissio1.97703546
15MP0009780_abnormal_chondrocyte_physiolo1.91045444
16MP0009046_muscle_twitch1.76025149
17MP0000920_abnormal_myelination1.71301858
18MP0001963_abnormal_hearing_physiology1.66562683
19MP0009745_abnormal_behavioral_response1.62946069
20MP0002653_abnormal_ependyma_morphology1.62816205
21MP0005646_abnormal_pituitary_gland1.62232955
22MP0004043_abnormal_pH_regulation1.59628217
23MP0001984_abnormal_olfaction1.56833914
24MP0005423_abnormal_somatic_nervous1.56382598
25MP0002063_abnormal_learning/memory/cond1.53875524
26MP0001501_abnormal_sleep_pattern1.51218878
27MP0003123_paternal_imprinting1.50941131
28MP0000569_abnormal_digit_pigmentation1.48880664
29MP0002064_seizures1.47718182
30MP0001177_atelectasis1.46755489
31MP0002272_abnormal_nervous_system1.45938816
32MP0003880_abnormal_central_pattern1.45929549
33MP0004270_analgesia1.42539985
34MP0000026_abnormal_inner_ear1.42481948
35MP0003787_abnormal_imprinting1.42393670
36MP0002572_abnormal_emotion/affect_behav1.38034853
37MP0001968_abnormal_touch/_nociception1.31124198
38MP0010386_abnormal_urinary_bladder1.29663559
39MP0002557_abnormal_social/conspecific_i1.29538307
40MP0004858_abnormal_nervous_system1.29393807
41MP0000604_amyloidosis1.28010441
42MP0001502_abnormal_circadian_rhythm1.26823312
43MP0002734_abnormal_mechanical_nocicepti1.26643512
44MP0002067_abnormal_sensory_capabilities1.25075550
45MP0004885_abnormal_endolymph1.23776931
46MP0003941_abnormal_skin_development1.15594257
47MP0003634_abnormal_glial_cell1.15132836
48MP0003122_maternal_imprinting1.12076786
49MP0000678_abnormal_parathyroid_gland1.10100768
50MP0002184_abnormal_innervation1.09970167
51MP0006072_abnormal_retinal_apoptosis1.07238141
52MP0001905_abnormal_dopamine_level1.05552817
53MP0001970_abnormal_pain_threshold1.04551828
54MP0002735_abnormal_chemical_nociception1.03996939
55MP0004924_abnormal_behavior1.03891888
56MP0005386_behavior/neurological_phenoty1.03891888
57MP0002736_abnormal_nociception_after1.02405364
58MP0005551_abnormal_eye_electrophysiolog1.02235799
59MP0002733_abnormal_thermal_nociception1.01619377
60MP0003633_abnormal_nervous_system1.01250696
61MP0000462_abnormal_digestive_system1.00751138
62MP0002638_abnormal_pupillary_reflex1.00587684
63MP0008874_decreased_physiological_sensi1.00324940
64MP0003045_fibrosis0.99774295
65MP0003632_abnormal_nervous_system0.99591618
66MP0003172_abnormal_lysosome_physiology0.97524868
67MP0005394_taste/olfaction_phenotype0.95880847
68MP0005499_abnormal_olfactory_system0.95880847
69MP0001348_abnormal_lacrimal_gland0.95218715
70MP0002229_neurodegeneration0.93594674
71MP0002882_abnormal_neuron_morphology0.92940356
72MP0001944_abnormal_pancreas_morphology0.92239921
73MP0004742_abnormal_vestibular_system0.90960950
74MP0008569_lethality_at_weaning0.88136689
75MP0000955_abnormal_spinal_cord0.87947805
76MP0001440_abnormal_grooming_behavior0.86744689
77MP0001188_hyperpigmentation0.82212992
78MP0009278_abnormal_bone_marrow0.81771750
79MP0004811_abnormal_neuron_physiology0.81171454
80MP0001986_abnormal_taste_sensitivity0.80898925
81MP0002693_abnormal_pancreas_physiology0.79786199
82MP0000778_abnormal_nervous_system0.79722620
83MP0008789_abnormal_olfactory_epithelium0.78314645
84MP0002751_abnormal_autonomic_nervous0.74765326
85MP0004510_myositis0.74464292
86MP0005535_abnormal_body_temperature0.73833635
87MP0002066_abnormal_motor_capabilities/c0.73484359
88MP0004145_abnormal_muscle_electrophysio0.72808266
89MP0008877_abnormal_DNA_methylation0.72068910
90MP0008872_abnormal_physiological_respon0.71643764
91MP0005253_abnormal_eye_physiology0.70925856
92MP0002249_abnormal_larynx_morphology0.70610658
93MP0006276_abnormal_autonomic_nervous0.70605480
94MP0001765_abnormal_ion_homeostasis0.70475878
95MP0001346_abnormal_lacrimal_gland0.70145697
96MP0009384_cardiac_valve_regurgitation0.69971087
97MP0005409_darkened_coat_color0.69679859
98MP0003183_abnormal_peptide_metabolism0.66916999
99MP0002752_abnormal_somatic_nervous0.66528169
100MP0000631_abnormal_neuroendocrine_gland0.65827011
101MP0003938_abnormal_ear_development0.65216216
102MP0008961_abnormal_basal_metabolism0.64693156
103MP0000579_abnormal_nail_morphology0.64063881
104MP0000566_synostosis0.63586773
105MP0006292_abnormal_olfactory_placode0.63427968
106MP0003705_abnormal_hypodermis_morpholog0.62416892
107MP0005623_abnormal_meninges_morphology0.61656982
108MP0001299_abnormal_eye_distance/0.61330607
109MP0000003_abnormal_adipose_tissue0.61228838
110MP0004142_abnormal_muscle_tone0.60549279
111MP0008260_abnormal_autophagy0.60366018
112MP0005310_abnormal_salivary_gland0.59671756
113MP0005220_abnormal_exocrine_pancreas0.59249633
114MP0003861_abnormal_nervous_system0.58743895
115MP0002009_preneoplasia0.57840830
116MP0000013_abnormal_adipose_tissue0.57536150
117MP0002089_abnormal_postnatal_growth/wei0.57510773
118MP0010769_abnormal_survival0.56758417
119MP0001666_abnormal_nutrient_absorption0.56577120
120MP0005171_absent_coat_pigmentation0.56353698
121MP0009672_abnormal_birth_weight0.55933119
122MP0003953_abnormal_hormone_level0.55026609
123MP0003137_abnormal_impulse_conducting0.54960022
124MP0002896_abnormal_bone_mineralization0.54095501
125MP0005166_decreased_susceptibility_to0.53832058
126MP0003075_altered_response_to0.53798003
127MP0002069_abnormal_eating/drinking_beha0.53374652
128MP0004130_abnormal_muscle_cell0.53273942
129MP0002873_normal_phenotype0.52998983
130MP0010768_mortality/aging0.52904291
131MP0003191_abnormal_cellular_cholesterol0.52088292
132MP0002169_no_abnormal_phenotype0.51623040
133MP0002152_abnormal_brain_morphology0.51587191
134MP0003631_nervous_system_phenotype0.51237940
135MP0010770_preweaning_lethality0.50687672
136MP0002082_postnatal_lethality0.50687672
137MP0004085_abnormal_heartbeat0.49336085
138MP0003956_abnormal_body_size0.48917307
139MP0001943_abnormal_respiration0.47451984

Predicted human phenotypes

RankGene SetZ-score
1Ankle clonus (HP:0011448)5.05410220
2Diplopia (HP:0000651)5.05283235
3Abnormality of binocular vision (HP:0011514)5.05283235
4Neurofibrillary tangles (HP:0002185)4.56129274
5Obstructive sleep apnea (HP:0002870)4.24169868
6Symphalangism affecting the phalanges of the hand (HP:0009773)4.18108719
7Focal motor seizures (HP:0011153)4.04865334
8Annular pancreas (HP:0001734)3.86461467
9Febrile seizures (HP:0002373)3.78758004
10Cerebral inclusion bodies (HP:0100314)3.74230325
11Spastic gait (HP:0002064)3.72218596
12Torticollis (HP:0000473)3.64950857
13Urinary bladder sphincter dysfunction (HP:0002839)3.63131660
14Abnormality of the middle phalanges of the toes (HP:0010183)3.54295511
15Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.46150589
16Papilledema (HP:0001085)3.41789045
17Dysmetria (HP:0001310)3.41177211
18Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)3.40822501
19Abnormality of the 1st metacarpal (HP:0010009)3.39634473
20Abnormality of the proximal phalanges of the hand (HP:0009834)3.36258298
21Impaired vibration sensation in the lower limbs (HP:0002166)3.32646980
22Neuronal loss in central nervous system (HP:0002529)3.31564355
23Abnormality of the distal phalanx of the thumb (HP:0009617)3.30784753
24Tetraplegia (HP:0002445)3.30167544
25Abnormal eating behavior (HP:0100738)3.28294556
26Mutism (HP:0002300)3.21175024
27Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)3.20640654
28Short tibia (HP:0005736)3.19926272
29Relative macrocephaly (HP:0004482)3.19865248
30Epileptic encephalopathy (HP:0200134)3.18104178
31Truncal ataxia (HP:0002078)3.17570036
32Cupped ribs (HP:0000887)3.13637151
33Focal dystonia (HP:0004373)3.09759708
34Intention tremor (HP:0002080)3.08915014
35Delusions (HP:0000746)3.06168968
36Flared iliac wings (HP:0002869)3.04424933
37Depression (HP:0000716)3.02927356
38Unilateral renal agenesis (HP:0000122)2.98119200
39Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.96108626
40Apathy (HP:0000741)2.93831737
41Status epilepticus (HP:0002133)2.92371697
42Cerebral hypomyelination (HP:0006808)2.90865530
43Aplasia/Hypoplasia of the tibia (HP:0005772)2.89632841
44Insomnia (HP:0100785)2.87410159
45Focal seizures (HP:0007359)2.87038545
46Myokymia (HP:0002411)2.86993054
47Craniofacial dystonia (HP:0012179)2.85086641
48Abnormality of the phalanges of the hallux (HP:0010057)2.83722022
49Clonus (HP:0002169)2.82515116
50Broad palm (HP:0001169)2.81638133
51Bradykinesia (HP:0002067)2.81423471
52Urinary urgency (HP:0000012)2.80065654
53Limb dystonia (HP:0002451)2.79178495
54Hip dysplasia (HP:0001385)2.74479023
55Hemiplegia (HP:0002301)2.74174762
56Visual hallucinations (HP:0002367)2.73786355
57Bronchomalacia (HP:0002780)2.72968409
58Peripheral hypomyelination (HP:0007182)2.70492119
59Congenital sensorineural hearing impairment (HP:0008527)2.67324054
60Sleep apnea (HP:0010535)2.67138878
61Akinesia (HP:0002304)2.66167306
62Lower limb muscle weakness (HP:0007340)2.58035012
63Anxiety (HP:0000739)2.57079552
64Diminished motivation (HP:0000745)2.56750996
65Flat acetabular roof (HP:0003180)2.56179182
66Impaired smooth pursuit (HP:0007772)2.54488421
67Flat capital femoral epiphysis (HP:0003370)2.53152999
68Neonatal short-limb short stature (HP:0008921)2.52206057
69Short phalanx of the thumb (HP:0009660)2.51521316
70Short middle phalanx of finger (HP:0005819)2.50333106
71Amblyopia (HP:0000646)2.49038750
72Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.46379205
73Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)2.46014482
74Aplasia involving bones of the upper limbs (HP:0009823)2.45834635
75Aplasia of the phalanges of the hand (HP:0009802)2.45834635
76Aplasia involving bones of the extremities (HP:0009825)2.45834635
77Prolonged QT interval (HP:0001657)2.45234907
78Aplasia/Hypoplasia involving the pelvis (HP:0009103)2.44182828
79Abnormal social behavior (HP:0012433)2.43134441
80Impaired social interactions (HP:0000735)2.43134441
81Short thorax (HP:0010306)2.42955602
82Stereotypic behavior (HP:0000733)2.42253233
83Atonic seizures (HP:0010819)2.41613958
84Rigidity (HP:0002063)2.40901284
85Lower limb amyotrophy (HP:0007210)2.40764474
86Abnormality of calcium-phosphate metabolism (HP:0100530)2.38754953
87Impaired vibratory sensation (HP:0002495)2.37083849
88Spinal canal stenosis (HP:0003416)2.34704254
89Abnormality of the 2nd finger (HP:0004100)2.32929980
90Spastic tetraparesis (HP:0001285)2.32573447
91Hypoplastic ischia (HP:0003175)2.31277811
92Dysdiadochokinesis (HP:0002075)2.28917215
93Bundle branch block (HP:0011710)2.26656054
94Retinal atrophy (HP:0001105)2.25452920
95Aplasia/hypoplasia of the femur (HP:0005613)2.24533290
96Turricephaly (HP:0000262)2.23529317
97Absence seizures (HP:0002121)2.22405911
98Abnormal EKG (HP:0003115)2.17989448
99Abnormality of ocular smooth pursuit (HP:0000617)2.15483951
100Spinal cord compression (HP:0002176)2.15350789
101Congenital stationary night blindness (HP:0007642)2.13968363
102Decreased circulating renin level (HP:0003351)2.13957146
103Shawl scrotum (HP:0000049)2.13674698
104Generalized tonic-clonic seizures (HP:0002069)2.12590183
105Abnormality of the epiphysis of the femoral head (HP:0010574)2.12063944
106Scanning speech (HP:0002168)2.11636808
107Pointed chin (HP:0000307)2.10365260
108Abnormality of the lower motor neuron (HP:0002366)2.10297575
109Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.09522038
110Action tremor (HP:0002345)2.09010942
111Flattened epiphyses (HP:0003071)2.08652869
112Abnormality of the epiphyses of the hand (HP:0005924)2.07213188
113Postural instability (HP:0002172)2.06984047
114Hemiparesis (HP:0001269)2.05044451
115Abnormality of polysaccharide metabolism (HP:0011012)2.04299219
116Abnormality of glycosaminoglycan metabolism (HP:0004371)2.04299219
117Abnormality of mucopolysaccharide metabolism (HP:0011020)2.04299219
118Ovoid vertebral bodies (HP:0003300)2.04276614
119Rapidly progressive (HP:0003678)2.04245464
120Hypoplastic ilia (HP:0000946)2.04175568
121Thickened helices (HP:0000391)2.04113355
122Choreoathetosis (HP:0001266)2.04094783
123Abnormality of the femoral head (HP:0003368)2.03380321
124Megalencephaly (HP:0001355)2.02086728
125Hyperparathyroidism (HP:0000843)2.02076123
126Upper limb amyotrophy (HP:0009129)2.01976224
127Distal upper limb amyotrophy (HP:0007149)2.01976224
128Heart block (HP:0012722)2.01754219
129Hypoplastic iliac wings (HP:0002866)2.00827651
130Hip contracture (HP:0003273)2.00609937
131Supranuclear gaze palsy (HP:0000605)2.00407924
132Absent phalangeal crease (HP:0006109)2.00379255
133Progressive cerebellar ataxia (HP:0002073)1.99798759
134Hypoplasia of the ulna (HP:0003022)1.98940616
135Dementia (HP:0000726)1.98198719
136Lower limb asymmetry (HP:0100559)1.98160733
137Ventricular fibrillation (HP:0001663)1.97952127
138Abnormality of the ischium (HP:0003174)1.97691583
139Bradycardia (HP:0001662)1.96879666
140Abnormal vertebral ossification (HP:0100569)1.94640988
141Dialeptic seizures (HP:0011146)1.93780983
142Dysmetric saccades (HP:0000641)1.93497767
143Intestinal fistula (HP:0100819)1.93350363
144Abnormality of carpal bone ossification (HP:0006257)1.92355467
145Split foot (HP:0001839)1.92144766
146Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843)1.91646034
147Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.91244900
148Abnormality of femoral epiphyses (HP:0006499)1.91244900
149Abnormality of saccadic eye movements (HP:0000570)1.91104572
150Abnormal finger flexion creases (HP:0006143)1.91083905
151Rectovaginal fistula (HP:0000143)1.90387210
152Rectal fistula (HP:0100590)1.90387210
153Abnormality of renin-angiotensin system (HP:0000847)1.90138920
154Short femoral neck (HP:0100864)1.88782065
155Incomplete penetrance (HP:0003829)1.88688577
156Urinary glycosaminoglycan excretion (HP:0003541)1.87461194
157Mucopolysacchariduria (HP:0008155)1.87461194
158Increased circulating renin level (HP:0000848)1.86405068
159Agitation (HP:0000713)1.84734930
160Lumbar hyperlordosis (HP:0002938)1.84264597
161Abnormal atrioventricular conduction (HP:0005150)1.83806226
162EEG with generalized epileptiform discharges (HP:0011198)1.83562504
163Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.83561337
164Syncope (HP:0001279)1.82949667
165Epileptiform EEG discharges (HP:0011182)1.82574336
166Hand muscle atrophy (HP:0009130)1.81452856
167Slow saccadic eye movements (HP:0000514)1.81272653
168Hyperacusis (HP:0010780)1.81142279
169Vertebral clefting (HP:0008428)1.81065434
170Genetic anticipation (HP:0003743)1.80024456
171Short humerus (HP:0005792)1.79787907
172Micromelia (HP:0002983)1.78046156
173Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.77695477
174Vertebral hypoplasia (HP:0008417)1.77695477
175Hypercortisolism (HP:0001578)1.77505233
176Hypsarrhythmia (HP:0002521)1.76890779
177Poor eye contact (HP:0000817)1.76845457
178Abnormality of the middle phalanges of the hand (HP:0009833)1.75586513
179Atrioventricular block (HP:0001678)1.74899142
180CNS hypomyelination (HP:0003429)1.74495519

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R5.26235330
2MAP3K123.63706249
3NTRK33.58130853
4PIK3CA3.17539787
5MAP3K42.97008227
6DDR22.74899625
7INSRR2.58001982
8MAPK152.56374868
9TNIK2.43732553
10MAP3K92.19999819
11AKT31.91676789
12EPHA41.82344880
13PLK21.79927705
14CDK191.76712883
15RIPK41.75759413
16MAP2K71.75543974
17LATS21.71063979
18ARAF1.68585034
19MET1.68243515
20DAPK21.63113586
21MAP2K41.57348724
22IRAK31.53012414
23NTRK21.48833612
24SIK21.46961561
25TYRO31.45093892
26CASK1.41174205
27MARK11.38926919
28STK381.36858342
29UHMK11.36103744
30PINK11.34216426
31WNK41.26785747
32NTRK11.25501460
33PRKD31.25094601
34TNK21.19548133
35WNK11.15971733
36MAP3K11.13299180
37CDC42BPA1.12726093
38CDK151.11386823
39CAMKK11.08272418
40PRKCH1.07654962
41DAPK11.06439123
42CDK11A1.06185615
43CDK181.05963026
44MINK11.05817472
45CAMK11.02461972
46YES11.02175081
47MAP2K20.94421705
48MAPK120.91975947
49CDK50.91878924
50CDK140.90685165
51ERBB30.89502373
52CAMK2D0.88284172
53MAPK130.87508180
54PHKG20.87023237
55PHKG10.87023237
56PAK60.86102564
57MAP3K110.84582960
58HIPK20.83375957
59SGK20.80390920
60GRK50.79093160
61WNK30.79041977
62FGFR20.78186226
63PAK30.77895609
64BRSK10.77770716
65PRKD20.76977032
66PDK10.76279384
67MAP3K20.75873485
68SGK10.74840771
69PDPK10.71960211
70CAMKK20.71852097
71SIK30.69865755
72TRIB30.69692793
73PRKCE0.69403505
74RIPK10.68407156
75BRAF0.68397477
76MATK0.67800674
77ICK0.66955573
78CAMK1G0.66813939
79BMPR20.65538451
80SGK4940.65493483
81SGK2230.65493483
82CAMK1D0.65266075
83SGK30.63956038
84ALK0.63862431
85PRKCG0.63805715
86PKN10.63278668
87PRKG20.59608189
88CDK30.59355084
89PRPF4B0.58713394
90BMX0.57386393
91OXSR10.55926660
92TAOK30.55505275
93MAP2K60.55175198
94CAMK2A0.55028188
95IRAK20.52769140
96MARK20.52751859
97FER0.51759773
98LMTK20.50671452
99PRKCZ0.48922976
100NEK60.48631664
101MAP3K130.48292475
102DYRK1B0.46618953
103MAP2K10.46558616
104CAMK40.45600700
105KSR20.44917365
106ERBB20.44804696
107CAMK2G0.43308404
108TESK10.42870307
109CAMK2B0.42285340
110RPS6KB10.41647041
111BRD40.41557905
112GRK10.40123213
113FYN0.38530874
114MAPK80.38481615
115STK110.38353423
116LIMK10.37041623
117EEF2K0.36520539
118RPS6KA30.35356836
119ROCK20.34921272
120DAPK30.34568012
121TAOK10.33223874
122PDGFRA0.32760432
123SMG10.32604210
124MAP3K70.32602824
125MAPK100.32472165
126GSK3B0.32379485
127FRK0.32191857
128TRPM70.32078239
129SIK10.31652537
130RPS6KA20.31458149
131DYRK1A0.30853928
132PRKCA0.30023444
133MAP3K60.29598071
134FES0.28469085
135ROCK10.26132721
136SRC0.25158927
137RET0.25131761
138MAPK70.23551941
139CSNK1E0.23031000

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009204.51039234
2Sulfur relay system_Homo sapiens_hsa041223.55855887
3Synaptic vesicle cycle_Homo sapiens_hsa047212.62315384
4Nicotine addiction_Homo sapiens_hsa050332.60825581
5Insulin secretion_Homo sapiens_hsa049112.42455452
6Vitamin B6 metabolism_Homo sapiens_hsa007502.17567009
7Olfactory transduction_Homo sapiens_hsa047402.02639543
8GABAergic synapse_Homo sapiens_hsa047272.01656982
9Maturity onset diabetes of the young_Homo sapiens_hsa049501.97549394
10Pancreatic secretion_Homo sapiens_hsa049721.96572448
11Circadian entrainment_Homo sapiens_hsa047131.91946518
12Morphine addiction_Homo sapiens_hsa050321.91227308
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.86217989
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.84763969
15Taste transduction_Homo sapiens_hsa047421.82787002
16Salivary secretion_Homo sapiens_hsa049701.75620915
17Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.72381875
18Glutamatergic synapse_Homo sapiens_hsa047241.66442423
19Type II diabetes mellitus_Homo sapiens_hsa049301.65548578
20Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.63589927
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.55752239
22Amphetamine addiction_Homo sapiens_hsa050311.50217858
23Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.47363569
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46070380
25Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.44857164
26Phototransduction_Homo sapiens_hsa047441.40343811
27Long-term potentiation_Homo sapiens_hsa047201.35836656
28Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.33102322
29Mineral absorption_Homo sapiens_hsa049781.30722776
30Gastric acid secretion_Homo sapiens_hsa049711.28721348
31Type I diabetes mellitus_Homo sapiens_hsa049401.28638170
32Cholinergic synapse_Homo sapiens_hsa047251.26970725
33Cocaine addiction_Homo sapiens_hsa050301.21569017
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.21447118
35Calcium signaling pathway_Homo sapiens_hsa040201.20442681
36Dopaminergic synapse_Homo sapiens_hsa047281.19856852
37Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.17220424
38Serotonergic synapse_Homo sapiens_hsa047261.11955104
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.08496503
40Collecting duct acid secretion_Homo sapiens_hsa049661.07198020
41ErbB signaling pathway_Homo sapiens_hsa040121.04249713
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.03776847
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01046147
44cAMP signaling pathway_Homo sapiens_hsa040241.00270162
45GnRH signaling pathway_Homo sapiens_hsa049120.99585811
46Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99110277
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94681510
48Bile secretion_Homo sapiens_hsa049760.94032142
49Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.90680100
50Protein digestion and absorption_Homo sapiens_hsa049740.88801599
51Oocyte meiosis_Homo sapiens_hsa041140.88073480
52VEGF signaling pathway_Homo sapiens_hsa043700.87117132
53Renin secretion_Homo sapiens_hsa049240.86737206
54Oxytocin signaling pathway_Homo sapiens_hsa049210.84630387
55Long-term depression_Homo sapiens_hsa047300.83674842
56Rap1 signaling pathway_Homo sapiens_hsa040150.79833892
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.76487566
58Arginine biosynthesis_Homo sapiens_hsa002200.76147398
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75532410
60Hedgehog signaling pathway_Homo sapiens_hsa043400.75507610
61Estrogen signaling pathway_Homo sapiens_hsa049150.75239240
62Vascular smooth muscle contraction_Homo sapiens_hsa042700.73742274
63Glucagon signaling pathway_Homo sapiens_hsa049220.73651459
64Vibrio cholerae infection_Homo sapiens_hsa051100.72391918
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71135244
66Histidine metabolism_Homo sapiens_hsa003400.70277560
67Melanogenesis_Homo sapiens_hsa049160.69128941
68Inositol phosphate metabolism_Homo sapiens_hsa005620.67985513
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.66902104
70Dilated cardiomyopathy_Homo sapiens_hsa054140.64992433
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64612052
72Arginine and proline metabolism_Homo sapiens_hsa003300.64105411
73Circadian rhythm_Homo sapiens_hsa047100.63997997
74Lysosome_Homo sapiens_hsa041420.61684472
75Gap junction_Homo sapiens_hsa045400.60235804
76Cardiac muscle contraction_Homo sapiens_hsa042600.60009616
77Prolactin signaling pathway_Homo sapiens_hsa049170.58839974
78Glioma_Homo sapiens_hsa052140.58399509
79Ovarian steroidogenesis_Homo sapiens_hsa049130.57663212
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.57256582
81Notch signaling pathway_Homo sapiens_hsa043300.56228161
82Endocytosis_Homo sapiens_hsa041440.55897731
83Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55319207
84SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54821150
85Thyroid hormone synthesis_Homo sapiens_hsa049180.53856393
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53835213
87mTOR signaling pathway_Homo sapiens_hsa041500.53790452
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.53268640
89Glycosaminoglycan degradation_Homo sapiens_hsa005310.51130008
90N-Glycan biosynthesis_Homo sapiens_hsa005100.50497945
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.50444025
92Axon guidance_Homo sapiens_hsa043600.50256760
93Dorso-ventral axis formation_Homo sapiens_hsa043200.49743910
94Fructose and mannose metabolism_Homo sapiens_hsa000510.49674611
95Choline metabolism in cancer_Homo sapiens_hsa052310.48854025
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48062441
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47986937
98MAPK signaling pathway_Homo sapiens_hsa040100.47939326
99Other glycan degradation_Homo sapiens_hsa005110.46097486
100Toll-like receptor signaling pathway_Homo sapiens_hsa046200.45126027
101Rheumatoid arthritis_Homo sapiens_hsa053230.44314233
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44228188
103Butanoate metabolism_Homo sapiens_hsa006500.42396251
104Endometrial cancer_Homo sapiens_hsa052130.41794789
105alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41701141
106Chemokine signaling pathway_Homo sapiens_hsa040620.41696063
107Tight junction_Homo sapiens_hsa045300.40893356
108Prion diseases_Homo sapiens_hsa050200.40518772
109Insulin signaling pathway_Homo sapiens_hsa049100.38991139
110Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38108426
111Ras signaling pathway_Homo sapiens_hsa040140.38042201
112Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.36645750
113Wnt signaling pathway_Homo sapiens_hsa043100.35115261
114Alcoholism_Homo sapiens_hsa050340.34365384
115Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33433809
116AMPK signaling pathway_Homo sapiens_hsa041520.33294763
1172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.32896543
118Fat digestion and absorption_Homo sapiens_hsa049750.32863934
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.32407076
120Fatty acid biosynthesis_Homo sapiens_hsa000610.27214097
121HIF-1 signaling pathway_Homo sapiens_hsa040660.25844620
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.24724253
123beta-Alanine metabolism_Homo sapiens_hsa004100.24662751
124Hippo signaling pathway_Homo sapiens_hsa043900.23921319
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.23543614
126Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.21834381

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