ANKRD27

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.72566543
2IMP biosynthetic process (GO:0006188)4.56787576
3nuclear pore complex assembly (GO:0051292)4.27907033
4folic acid-containing compound biosynthetic process (GO:0009396)4.26867050
5IMP metabolic process (GO:0046040)4.18860312
6nuclear pore organization (GO:0006999)4.14712029
7negative regulation of erythrocyte differentiation (GO:0045647)4.12007218
8protein localization to kinetochore (GO:0034501)4.01713005
9mitotic nuclear envelope disassembly (GO:0007077)4.01072845
10regulation of RNA export from nucleus (GO:0046831)3.98532460
11DNA strand elongation involved in DNA replication (GO:0006271)3.85173280
12nuclear envelope disassembly (GO:0051081)3.77192100
13membrane disassembly (GO:0030397)3.77192100
14DNA replication initiation (GO:0006270)3.73506920
15protoporphyrinogen IX metabolic process (GO:0046501)3.71658556
16nucleobase biosynthetic process (GO:0046112)3.71090234
17DNA strand elongation (GO:0022616)3.66820237
18negative regulation of phagocytosis (GO:0050765)3.53552814
19regulation of translational termination (GO:0006449)3.49578138
20mitotic sister chromatid cohesion (GO:0007064)3.40933196
21DNA duplex unwinding (GO:0032508)3.40083699
22telomere maintenance via semi-conservative replication (GO:0032201)3.39242285
23pore complex assembly (GO:0046931)3.39100734
24proline biosynthetic process (GO:0006561)3.36365971
25DNA geometric change (GO:0032392)3.36050746
26ribosomal small subunit assembly (GO:0000028)3.35807801
27regulation of nucleobase-containing compound transport (GO:0032239)3.33594533
28NIK/NF-kappaB signaling (GO:0038061)3.23416899
29COPI coating of Golgi vesicle (GO:0048205)3.22804933
30Golgi transport vesicle coating (GO:0048200)3.22804933
31DNA synthesis involved in DNA repair (GO:0000731)3.20701895
32antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.20239288
33antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.20239288
34protein localization to chromosome, centromeric region (GO:0071459)3.19595518
35protein export from nucleus (GO:0006611)3.07776828
36negative regulation of histone methylation (GO:0031061)3.06139311
37telomere maintenance via recombination (GO:0000722)3.05767574
38mitotic chromosome condensation (GO:0007076)3.05014721
39purine nucleobase biosynthetic process (GO:0009113)3.04999919
40erythrocyte maturation (GO:0043249)3.04503402
41regulation of translational fidelity (GO:0006450)3.04095473
42regulation of histone H3-K4 methylation (GO:0051569)3.02222582
43formation of translation preinitiation complex (GO:0001731)3.01621620
44negative regulation of DNA repair (GO:0045738)3.01005667
45glucocorticoid receptor signaling pathway (GO:0042921)2.99833213
46regulation of histone H3-K9 methylation (GO:0051570)2.99196070
47mitotic sister chromatid segregation (GO:0000070)2.96322413
48sister chromatid segregation (GO:0000819)2.94126646
49protein-DNA complex disassembly (GO:0032986)2.94083427
50nucleosome disassembly (GO:0006337)2.94083427
51mitotic recombination (GO:0006312)2.93566646
52regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.92761708
53nuclear envelope organization (GO:0006998)2.92266132
543-UTR-mediated mRNA stabilization (GO:0070935)2.92011926
55protoporphyrinogen IX biosynthetic process (GO:0006782)2.91481477
56negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.88625647
57embryonic process involved in female pregnancy (GO:0060136)2.86622914
58regulation of histone H3-K27 methylation (GO:0061085)2.85881332
59DNA replication checkpoint (GO:0000076)2.84980370
60tetrahydrofolate metabolic process (GO:0046653)2.82576958
61telomere maintenance via telomere lengthening (GO:0010833)2.82091453
62regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.81833107
63chromosome condensation (GO:0030261)2.79732797
64DNA replication-dependent nucleosome assembly (GO:0006335)2.77258378
65DNA replication-dependent nucleosome organization (GO:0034723)2.77258378
66viral mRNA export from host cell nucleus (GO:0046784)2.77055973
67regulation of spindle organization (GO:0090224)2.76909624
68poly(A)+ mRNA export from nucleus (GO:0016973)2.74676654
69translesion synthesis (GO:0019985)2.74652850
70regulation of mitotic spindle organization (GO:0060236)2.74451392
71necroptotic process (GO:0070266)2.73600304
72histone H2B ubiquitination (GO:0033523)2.73276973
73pentose-phosphate shunt (GO:0006098)2.70074437
74DNA conformation change (GO:0071103)2.69651333
75antigen processing and presentation of endogenous antigen (GO:0019883)2.68215820
76corticosteroid receptor signaling pathway (GO:0031958)2.65268218
77pinocytosis (GO:0006907)2.64998671
78cellular protein complex localization (GO:0034629)2.64307227
79negative regulation of RNA splicing (GO:0033119)2.61913184
80megakaryocyte development (GO:0035855)2.60013035
81spliceosomal tri-snRNP complex assembly (GO:0000244)2.59818359
82postreplication repair (GO:0006301)2.59708678
83pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.59044027
84regulation of histone methylation (GO:0031060)2.58836747
85somatic diversification of immune receptors via somatic mutation (GO:0002566)2.58508315
86somatic hypermutation of immunoglobulin genes (GO:0016446)2.58508315
87histone-serine phosphorylation (GO:0035404)2.58213674
88DNA packaging (GO:0006323)2.57937919
89mRNA transport (GO:0051028)2.57898104
90protein complex localization (GO:0031503)2.57839480
91dosage compensation (GO:0007549)2.56596632
92DNA topological change (GO:0006265)2.55103928
93positive regulation of chromosome segregation (GO:0051984)2.54217688
94T cell apoptotic process (GO:0070231)2.53682833
95negative regulation of mRNA metabolic process (GO:1903312)2.53429222
96definitive hemopoiesis (GO:0060216)2.53398396
97NADPH regeneration (GO:0006740)2.52855156
98peptidyl-lysine dimethylation (GO:0018027)2.52724805
99snRNA metabolic process (GO:0016073)2.52258574
100heterochromatin organization (GO:0070828)2.51738131
101establishment of chromosome localization (GO:0051303)2.51033828
102chromatin remodeling at centromere (GO:0031055)2.50738376
103pre-miRNA processing (GO:0031054)2.48674924
104chromosome segregation (GO:0007059)2.48593113
105tRNA aminoacylation for protein translation (GO:0006418)2.48434128
106mRNA export from nucleus (GO:0006406)2.47205156
107positive regulation of gamma-delta T cell activation (GO:0046645)2.46539862
108monoubiquitinated protein deubiquitination (GO:0035520)2.45398632
109positive regulation of histone methylation (GO:0031062)2.45388528
110positive regulation of protein import into nucleus, translocation (GO:0033160)2.45376241
111regulation of DNA damage checkpoint (GO:2000001)2.44612146
112mitotic metaphase plate congression (GO:0007080)2.44516724
113telomere maintenance (GO:0000723)2.44513733
114erythrocyte development (GO:0048821)2.44190419
115CENP-A containing nucleosome assembly (GO:0034080)2.44024069
116pteridine-containing compound biosynthetic process (GO:0042559)2.43788612
117nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.43089718
118negative regulation of necroptotic process (GO:0060546)2.43043600
119telomere organization (GO:0032200)2.41776310
120chromatin assembly (GO:0031497)2.41600415
121pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.41514352
122UMP biosynthetic process (GO:0006222)2.41514352
123pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.41514352
124UMP metabolic process (GO:0046049)2.41514352
125granulocyte differentiation (GO:0030851)2.41158149
126histone H3-K36 demethylation (GO:0070544)2.40688849
127chromatin assembly or disassembly (GO:0006333)2.40556516
128regulation of necroptotic process (GO:0060544)2.40463867
129ribosome biogenesis (GO:0042254)2.39910044
130regulation of sister chromatid cohesion (GO:0007063)2.39219094
131RNA export from nucleus (GO:0006405)2.38743878
132nucleotide-excision repair, DNA gap filling (GO:0006297)2.38672390
133nucleobase-containing small molecule interconversion (GO:0015949)2.38643821
134hepatocyte apoptotic process (GO:0097284)2.38444206
135peptidyl-arginine omega-N-methylation (GO:0035247)2.38372979
136nuclear export (GO:0051168)2.38162665
137regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.35676920
138regulation of nuclear cell cycle DNA replication (GO:0033262)2.34956508
139negative regulation of mRNA processing (GO:0050686)2.33339934
140base-excision repair (GO:0006284)2.33133469
141protein localization to chromosome (GO:0034502)2.32723139
142positive regulation of B cell differentiation (GO:0045579)2.32500596
143metaphase plate congression (GO:0051310)2.31075151
144DNA replication-independent nucleosome organization (GO:0034724)2.30662403
145DNA replication-independent nucleosome assembly (GO:0006336)2.30662403
146maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.29371113
147mRNA stabilization (GO:0048255)2.28729510
148RNA stabilization (GO:0043489)2.28729510
149maturation of SSU-rRNA (GO:0030490)2.28342916
150regulation of protein heterodimerization activity (GO:0043497)2.26969839
151snRNA processing (GO:0016180)2.26300156
152mRNA cleavage (GO:0006379)2.26034392
153ribosome assembly (GO:0042255)2.25995480

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.39429651
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.58528930
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.43165545
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.32648986
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.01928766
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.95986777
7MYC_22102868_ChIP-Seq_BL_Human2.64615825
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.41286357
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.19346477
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.15261127
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.04185106
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.02911465
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.01123220
14SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.96167685
15GATA1_22025678_ChIP-Seq_K562_Human1.95418928
16STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.86027869
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.84668332
18NELFA_20434984_ChIP-Seq_ESCs_Mouse1.83957522
19SCL_19346495_ChIP-Seq_HPC-7_Human1.82983601
20RBPJ_22232070_ChIP-Seq_NCS_Mouse1.77897649
21ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.77744706
22VDR_21846776_ChIP-Seq_THP-1_Human1.76283226
23ELF1_17652178_ChIP-ChIP_JURKAT_Human1.75957205
24CIITA_25753668_ChIP-Seq_RAJI_Human1.75671198
25MYB_21317192_ChIP-Seq_ERMYB_Mouse1.74965035
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.71837215
27* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69999024
28EST1_17652178_ChIP-ChIP_JURKAT_Human1.68019257
29AR_21909140_ChIP-Seq_LNCAP_Human1.67815667
30MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.64299203
31* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.60709655
32XRN2_22483619_ChIP-Seq_HELA_Human1.57577104
33PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.54062582
34NCOR1_26117541_ChIP-Seq_K562_Human1.54022630
35KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.53334371
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52951747
37ZNF263_19887448_ChIP-Seq_K562_Human1.52138489
38IRF8_22096565_ChIP-ChIP_GC-B_Human1.51568750
39STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.50741233
40SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.50246526
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.49684001
42FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.48497300
43VDR_23849224_ChIP-Seq_CD4+_Human1.44736347
44KDM5A_27292631_Chip-Seq_BREAST_Human1.42717645
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.42235516
46ETS1_20019798_ChIP-Seq_JURKAT_Human1.41881087
47CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.41653211
48FOXP3_21729870_ChIP-Seq_TREG_Human1.40408175
49TFEB_21752829_ChIP-Seq_HELA_Human1.39525072
50* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.38796040
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.36668562
52NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.35787737
53MYB_26560356_Chip-Seq_TH2_Human1.35383277
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34191861
55* GATA1_19941826_ChIP-Seq_K562_Human1.33441161
56MYB_26560356_Chip-Seq_TH1_Human1.32643834
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31818467
58* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.31439038
59CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.31171247
60* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.30504179
61* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.30106229
62ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29877513
63MAF_26560356_Chip-Seq_TH1_Human1.29317325
64SPI1_23547873_ChIP-Seq_NB4_Human1.28918963
65FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.28611444
66GABP_17652178_ChIP-ChIP_JURKAT_Human1.28106626
67KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.26388585
68TCF7_22412390_ChIP-Seq_EML_Mouse1.25595501
69* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.25144019
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.23944794
71BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23579758
72CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23555893
73GABP_19822575_ChIP-Seq_HepG2_Human1.23003030
74STAT3_1855785_ChIP-Seq_MESCs_Mouse1.22395197
75NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22357599
76UTX_26944678_Chip-Seq_JUKART_Human1.21384805
77JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.19398929
78RUNX1_22412390_ChIP-Seq_EML_Mouse1.18535655
79DCP1A_22483619_ChIP-Seq_HELA_Human1.17828325
80CHD1_26751641_Chip-Seq_LNCaP_Human1.16676972
81NANOG_18555785_ChIP-Seq_MESCs_Mouse1.16515260
82ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.14734947
83YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14319950
84IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.13468548
85GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12567345
86TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11810905
87HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.11490408
88CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.10574299
89* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09860565
90TTF2_22483619_ChIP-Seq_HELA_Human1.09528012
91KLF4_18555785_ChIP-Seq_MESCs_Mouse1.08283484
92ELK1_19687146_ChIP-ChIP_HELA_Human1.07994079
93* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07839235
94FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07735841
95STAT4_19710469_ChIP-ChIP_TH1__Mouse1.07288229
96* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.05283548
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04366073
98NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.04307997
99* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.04221334
100KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04077981
101RACK7_27058665_Chip-Seq_MCF-7_Human1.03377744
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02690535
103DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02156088
104TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01751121
105TP63_17297297_ChIP-ChIP_HaCaT_Human1.01456629
106ATF3_27146783_Chip-Seq_COLON_Human1.01311354
107THAP11_20581084_ChIP-Seq_MESCs_Mouse1.01116323
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01104184
109KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.00933856
110CLOCK_20551151_ChIP-Seq_293T_Human0.99597232
111IRF8_21731497_ChIP-ChIP_J774_Mouse0.97909312
112TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97861849
113VDR_24763502_ChIP-Seq_THP-1_Human0.97833960
114CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97328658
115* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96874581
116SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96369028
117KDM2B_26808549_Chip-Seq_DND41_Human0.95494143
118ELK3_25401928_ChIP-Seq_HUVEC_Human0.94090184
119KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93483395
120POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93303670
121CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.93107951
122KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.92927502
123KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.92378856

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.59076990
2MP0002396_abnormal_hematopoietic_system3.34905594
3MP0010094_abnormal_chromosome_stability3.08729175
4MP0005451_abnormal_body_composition3.02874889
5MP0003111_abnormal_nucleus_morphology3.01809764
6MP0008057_abnormal_DNA_replication3.00620523
7MP0003693_abnormal_embryo_hatching2.77132880
8MP0003077_abnormal_cell_cycle2.65052394
9MP0004957_abnormal_blastocyst_morpholog2.56581364
10MP0010307_abnormal_tumor_latency2.48737862
11MP0003763_abnormal_thymus_physiology2.29038041
12MP0005397_hematopoietic_system_phenotyp2.13835923
13MP0001545_abnormal_hematopoietic_system2.13835923
14MP0004808_abnormal_hematopoietic_stem2.09607024
15MP0003705_abnormal_hypodermis_morpholog2.05277437
16MP0008260_abnormal_autophagy1.88502769
17MP0008007_abnormal_cellular_replicative1.83591658
18MP0002166_altered_tumor_susceptibility1.75198326
19MP0003806_abnormal_nucleotide_metabolis1.72814619
20MP0003566_abnormal_cell_adhesion1.70511780
21MP0002398_abnormal_bone_marrow1.66937492
22MP0005464_abnormal_platelet_physiology1.65623087
23MP0000685_abnormal_immune_system1.63273398
24MP0000350_abnormal_cell_proliferation1.62774520
25MP0004233_abnormal_muscle_weight1.60860761
26MP0002006_tumorigenesis1.59259160
27MP0008058_abnormal_DNA_repair1.59225267
28MP0001730_embryonic_growth_arrest1.59007003
29MP0001835_abnormal_antigen_presentation1.57399329
30MP0003123_paternal_imprinting1.56443762
31MP0005023_abnormal_wound_healing1.54140847
32MP0002009_preneoplasia1.51575161
33MP0002796_impaired_skin_barrier1.51307295
34MP0009333_abnormal_splenocyte_physiolog1.49105467
35MP0002722_abnormal_immune_system1.48089133
36MP0005076_abnormal_cell_differentiation1.46108135
37MP0000689_abnormal_spleen_morphology1.45187924
38MP0003300_gastrointestinal_ulcer1.41841151
39MP0000703_abnormal_thymus_morphology1.41637735
40MP0002019_abnormal_tumor_incidence1.39837050
41MP0005501_abnormal_skin_physiology1.38519074
42MP0001915_intracranial_hemorrhage1.37709741
43MP0006054_spinal_hemorrhage1.36596662
44MP0001800_abnormal_humoral_immune1.36018838
45MP0000490_abnormal_crypts_of1.34569809
46MP0001849_ear_inflammation1.34472675
47MP0005621_abnormal_cell_physiology1.34354046
48MP0010234_abnormal_vibrissa_follicle1.31205164
49MP0003191_abnormal_cellular_cholesterol1.30707143
50MP0004147_increased_porphyrin_level1.28288900
51MP0003453_abnormal_keratinocyte_physiol1.28283498
52MP0000858_altered_metastatic_potential1.28228447
53MP0002429_abnormal_blood_cell1.27363979
54MP0001661_extended_life_span1.27082763
55MP0003221_abnormal_cardiomyocyte_apopto1.23422922
56MP0000716_abnormal_immune_system1.23157090
57MP0003656_abnormal_erythrocyte_physiolo1.22671965
58MP0000358_abnormal_cell_content/1.21047665
59MP0002405_respiratory_system_inflammati1.19352785
60MP0009672_abnormal_birth_weight1.18556321
61MP0001853_heart_inflammation1.18328774
62MP0005384_cellular_phenotype1.18011440
63MP0003436_decreased_susceptibility_to1.17879343
64MP0005666_abnormal_adipose_tissue1.16542608
65MP0002420_abnormal_adaptive_immunity1.16487595
66MP0000313_abnormal_cell_death1.16123948
67MP0001672_abnormal_embryogenesis/_devel1.15996289
68MP0005380_embryogenesis_phenotype1.15996289
69MP0002086_abnormal_extraembryonic_tissu1.15884521
70MP0001697_abnormal_embryo_size1.15215330
71MP0001819_abnormal_immune_cell1.15109936
72MP0002452_abnormal_antigen_presenting1.14719978
73MP0008438_abnormal_cutaneous_collagen1.13545562
74MP0002080_prenatal_lethality1.13369384
75MP0003984_embryonic_growth_retardation1.12362854
76MP0000465_gastrointestinal_hemorrhage1.10419663
77MP0005058_abnormal_lysosome_morphology1.10345079
78MP0002088_abnormal_embryonic_growth/wei1.09753558
79MP0006035_abnormal_mitochondrial_morpho1.07734316
80MP0008932_abnormal_embryonic_tissue1.07250871
81MP0002723_abnormal_immune_serum1.07242280
82MP0004264_abnormal_extraembryonic_tissu1.05757737
83MP0005671_abnormal_response_to1.05602309
84MP0001348_abnormal_lacrimal_gland0.99901918
85MP0004947_skin_inflammation0.99122897
86MP0001873_stomach_inflammation0.98560771
87MP0009931_abnormal_skin_appearance0.98171009
88MP0002877_abnormal_melanocyte_morpholog0.97498954
89MP0003303_peritoneal_inflammation0.97269846
90MP0000598_abnormal_liver_morphology0.97113578
91MP0004197_abnormal_fetal_growth/weight/0.96053221
92MP0005083_abnormal_biliary_tract0.95696747
93MP0005275_abnormal_skin_tensile0.95641392
94MP0002139_abnormal_hepatobiliary_system0.95517197
95MP0005025_abnormal_response_to0.95468856
96MP0009785_altered_susceptibility_to0.94163676
97MP0003786_premature_aging0.93923127
98MP0000015_abnormal_ear_pigmentation0.92972206
99MP0001216_abnormal_epidermal_layer0.92283856
100MP0003718_maternal_effect0.91799083
101MP0002419_abnormal_innate_immunity0.90403304
102MP0001243_abnormal_dermal_layer0.90042519
103MP0001764_abnormal_homeostasis0.88252156
104MP0005365_abnormal_bile_salt0.86413996
105MP0001845_abnormal_inflammatory_respons0.86145933
106MP0010155_abnormal_intestine_physiology0.85623774
107MP0005075_abnormal_melanosome_morpholog0.84937763
108MP0001851_eye_inflammation0.84603898
109MP0010630_abnormal_cardiac_muscle0.84521041
110MP0001790_abnormal_immune_system0.83767671
111MP0005387_immune_system_phenotype0.83767671
112MP0002060_abnormal_skin_morphology0.83343787
113MP0009697_abnormal_copulation0.83220738
114MP0005000_abnormal_immune_tolerance0.80901227
115MP0003279_aneurysm0.80710979
116MP0009278_abnormal_bone_marrow0.79596915
117MP0002084_abnormal_developmental_patter0.79556595
118MP0003172_abnormal_lysosome_physiology0.79286838
119MP0003943_abnormal_hepatobiliary_system0.79191662
120MP0000609_abnormal_liver_physiology0.79047369
121MP0004185_abnormal_adipocyte_glucose0.77379258
122MP0008877_abnormal_DNA_methylation0.75890500
123MP0005375_adipose_tissue_phenotype0.75667813
124MP0005670_abnormal_white_adipose0.75398745
125MP0002085_abnormal_embryonic_tissue0.75298905
126MP0003567_abnormal_fetal_cardiomyocyte0.74491595
127MP0009703_decreased_birth_body0.73655744
128MP0000377_abnormal_hair_follicle0.72545765
129MP0001727_abnormal_embryo_implantation0.71275614
130MP0003091_abnormal_cell_migration0.67564956
131MP0008004_abnormal_stomach_pH0.65885645
132MP0010678_abnormal_skin_adnexa0.65673857
133MP0000747_muscle_weakness0.62702673

Predicted human phenotypes

RankGene SetZ-score
1Thrombocytosis (HP:0001894)3.92722823
2Reticulocytosis (HP:0001923)3.32495119
3Progressive muscle weakness (HP:0003323)3.25050544
4Cutaneous melanoma (HP:0012056)3.09434390
5Aplastic anemia (HP:0001915)3.05874537
6Ankyloglossia (HP:0010296)2.93670856
7Insidious onset (HP:0003587)2.84702736
8Termporal pattern (HP:0011008)2.84702736
9Chromsome breakage (HP:0040012)2.84636996
10Abnormality of the fingertips (HP:0001211)2.83634357
11Progressive external ophthalmoplegia (HP:0000590)2.81787711
12Abnormal platelet volume (HP:0011876)2.81313343
13Birth length less than 3rd percentile (HP:0003561)2.73736380
14Increased mean platelet volume (HP:0011877)2.72537338
15Myelodysplasia (HP:0002863)2.72362511
16Abnormal gallbladder physiology (HP:0012438)2.71405145
17Cholecystitis (HP:0001082)2.71405145
18Microvesicular hepatic steatosis (HP:0001414)2.68547786
19Amaurosis fugax (HP:0100576)2.67103489
20Deep philtrum (HP:0002002)2.60001837
21Abnormality of oral frenula (HP:0000190)2.59167537
22Dysmetric saccades (HP:0000641)2.58148685
23Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.56315270
24Volvulus (HP:0002580)2.55811316
25Protrusio acetabuli (HP:0003179)2.54501090
26Acute lymphatic leukemia (HP:0006721)2.52753468
27Cervical subluxation (HP:0003308)2.46346188
28Ependymoma (HP:0002888)2.45304649
29Abnormality of pyrimidine metabolism (HP:0004353)2.41584652
30Agnosia (HP:0010524)2.39950479
31Recurrent viral infections (HP:0004429)2.38732955
32Acute myeloid leukemia (HP:0004808)2.37939809
33Abnormality of chromosome stability (HP:0003220)2.36218014
34Fatigue (HP:0012378)2.35823318
35Biconcave vertebral bodies (HP:0004586)2.35714914
36Broad face (HP:0000283)2.34167538
37Abnormality of the calcaneus (HP:0008364)2.34013685
38Basal cell carcinoma (HP:0002671)2.33459754
39Chromosomal breakage induced by crosslinking agents (HP:0003221)2.29103635
40Broad palm (HP:0001169)2.28852154
41Colon cancer (HP:0003003)2.26553005
42Medulloblastoma (HP:0002885)2.25437374
43Hyperacusis (HP:0010780)2.22824336
44Multiple enchondromatosis (HP:0005701)2.21256235
45Distal lower limb amyotrophy (HP:0008944)2.19793560
46Abnormal platelet function (HP:0011869)2.18470018
47Impaired platelet aggregation (HP:0003540)2.18470018
48Squamous cell carcinoma (HP:0002860)2.17243478
49Petechiae (HP:0000967)2.14950039
50Syringomyelia (HP:0003396)2.14873098
51Spinal cord lesions (HP:0100561)2.14873098
52Epistaxis (HP:0000421)2.14255301
53Abnormality of the heme biosynthetic pathway (HP:0010472)2.13255382
54Septate vagina (HP:0001153)2.11235741
55IgM deficiency (HP:0002850)2.10844801
56Abnormality of the anterior horn cell (HP:0006802)2.10807200
57Degeneration of anterior horn cells (HP:0002398)2.10807200
58Increased nuchal translucency (HP:0010880)2.09221501
59Polycythemia (HP:0001901)2.08206565
60Insomnia (HP:0100785)2.06564307
61Heterotopia (HP:0002282)2.03516401
62Hypertensive crisis (HP:0100735)2.03497244
63Colitis (HP:0002583)2.02091518
64Increased density of long bones (HP:0006392)2.01192184
65Cholelithiasis (HP:0001081)2.00247378
66Gastrointestinal inflammation (HP:0004386)1.99996636
6711 pairs of ribs (HP:0000878)1.98741675
68Oral leukoplakia (HP:0002745)1.96737469
69Reticulocytopenia (HP:0001896)1.96120421
70Abnormality of the thoracic spine (HP:0100711)1.95668734
71Viral hepatitis (HP:0006562)1.95604040
72Absent thumb (HP:0009777)1.94782671
73Nephroblastoma (Wilms tumor) (HP:0002667)1.94721089
74Mesomelia (HP:0003027)1.91581663
75Neonatal hypoglycemia (HP:0001998)1.90497926
76Flat acetabular roof (HP:0003180)1.90239518
77Rhabdomyosarcoma (HP:0002859)1.89252002
78Poikilocytosis (HP:0004447)1.88653426
79Selective tooth agenesis (HP:0001592)1.88184596
80Orthostatic hypotension (HP:0001278)1.86822370
81Cellulitis (HP:0100658)1.86422649
82Centrally nucleated skeletal muscle fibers (HP:0003687)1.85948764
83Abnormality of T cells (HP:0002843)1.85817236
84High pitched voice (HP:0001620)1.85690387
85Aplasia/Hypoplasia of the uvula (HP:0010293)1.84738517
86T lymphocytopenia (HP:0005403)1.84537441
87Ragged-red muscle fibers (HP:0003200)1.84514273
88Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.83183791
89Short 4th metacarpal (HP:0010044)1.83183791
90Abnormal number of erythroid precursors (HP:0012131)1.83070994
91Deviation of the thumb (HP:0009603)1.81679237
92Bone marrow hypocellularity (HP:0005528)1.79871549
93Poikiloderma (HP:0001029)1.79738739
94Meckel diverticulum (HP:0002245)1.79382964
95Prolonged bleeding time (HP:0003010)1.79079124
96Abnormality of cells of the erythroid lineage (HP:0012130)1.78632537
97Periodontitis (HP:0000704)1.77956902
98Abnormality of T cell physiology (HP:0011840)1.77847246
99Prominent nose (HP:0000448)1.77531124
100Increased connective tissue (HP:0009025)1.77284812
101Cafe-au-lait spot (HP:0000957)1.76493232
102Thoracic kyphosis (HP:0002942)1.76490919
103Sandal gap (HP:0001852)1.76124339
104Pallor (HP:0000980)1.75895872
105Abnormality of the ileum (HP:0001549)1.75710099
106Clubbing of toes (HP:0100760)1.75304958
107Asymmetry of the thorax (HP:0001555)1.74305209
108Recurrent fungal infections (HP:0002841)1.74023462
109Persistence of primary teeth (HP:0006335)1.73389192
110Abnormal large intestine physiology (HP:0012700)1.73310182
111Inflammation of the large intestine (HP:0002037)1.72766889
112Ectopic kidney (HP:0000086)1.72754282
113Embryonal renal neoplasm (HP:0011794)1.72463106
114Long palpebral fissure (HP:0000637)1.72317121
115Slow saccadic eye movements (HP:0000514)1.72048124
116Biliary tract neoplasm (HP:0100574)1.69888393
117Elevated erythrocyte sedimentation rate (HP:0003565)1.69575767
118Aplasia/Hypoplasia of the thymus (HP:0010515)1.69573917
119Relative macrocephaly (HP:0004482)1.69558873
120Abnormality of T cell number (HP:0011839)1.69289518
121Entropion (HP:0000621)1.69156850
122Acanthocytosis (HP:0001927)1.68816103
123Lymphoma (HP:0002665)1.68754243
124Skin tags (HP:0010609)1.68676386
125Metaphyseal cupping (HP:0003021)1.68435209
126Premature ovarian failure (HP:0008209)1.67538960
127Abnormality of reticulocytes (HP:0004312)1.66714655
128Prominent metopic ridge (HP:0005487)1.66247119
129Deformed tarsal bones (HP:0008119)1.66067898
130Bowel incontinence (HP:0002607)1.65762712
131Autoimmune hemolytic anemia (HP:0001890)1.65621389
132Abnormality of DNA repair (HP:0003254)1.65271038
133Adenoma sebaceum (HP:0009720)1.65093786
134Angiofibromas (HP:0010615)1.65093786
135Long eyelashes (HP:0000527)1.64677216
136Abnormality of the preputium (HP:0100587)1.64668983
137Abnormality of iron homeostasis (HP:0011031)1.64369299
138Missing ribs (HP:0000921)1.62968485
139Abnormal gallbladder morphology (HP:0012437)1.62541287
140Increased IgE level (HP:0003212)1.62004410
141Arterial thrombosis (HP:0004420)1.61871609
142Radial bowing (HP:0002986)1.61148889
143Spontaneous hematomas (HP:0007420)1.60924851
144Gastrointestinal carcinoma (HP:0002672)1.60656255
145Malignant gastrointestinal tract tumors (HP:0006749)1.60656255
146Abnormality of nail color (HP:0100643)1.60441439
147Germ cell neoplasia (HP:0100728)1.60247628
148Gingival bleeding (HP:0000225)1.60119132
149Micronodular cirrhosis (HP:0001413)1.59479556
150Neoplasm of the oral cavity (HP:0100649)1.59077751
151Hypochromic microcytic anemia (HP:0004840)1.58776613
152Osteomyelitis (HP:0002754)1.58161398
153Abnormal delayed hypersensitivity skin test (HP:0002963)1.56991751
154Hypergonadotropic hypogonadism (HP:0000815)1.56887881
155Neoplasm of the respiratory system (HP:0100606)1.56152218
156Sparse lateral eyebrow (HP:0005338)1.56098994
157Lower limb hyperreflexia (HP:0002395)1.56090009
158Abnormal foot bone ossification (HP:0010675)1.56005112
159Genu recurvatum (HP:0002816)1.55980816
160Progressive hearing impairment (HP:0001730)1.55973831
161Astrocytoma (HP:0009592)1.55791912
162Abnormality of the astrocytes (HP:0100707)1.55791912
163Proximal placement of thumb (HP:0009623)1.55539197
164Osteolytic defects of the phalanges of the hand (HP:0009771)1.54880508
165Osteolytic defects of the hand bones (HP:0009699)1.54880508
166Seborrheic dermatitis (HP:0001051)1.54619586
167Deep palmar crease (HP:0006191)1.54561314
168Freckling (HP:0001480)1.54098117

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.12110758
2PKN23.22626743
3PRPF4B3.16387578
4CDC73.02116294
5FLT32.62088029
6SMG12.57496129
7IRAK32.51594343
8STK102.37422921
9PBK2.35743512
10MAP4K12.25032323
11NEK22.04763073
12RPS6KB21.99296316
13TRIB31.94717329
14TSSK61.93407518
15MAP2K31.91688176
16ICK1.84531531
17WEE11.82029458
18JAK31.73581734
19RPS6KA41.62581075
20PIM21.62218161
21PASK1.61869165
22SCYL21.60621182
23BRSK21.53281904
24CDK121.53144951
25TGFBR11.52658385
26MAP3K61.49752629
27NEK11.48415362
28ATR1.44733913
29RIPK41.42570661
30TAOK21.42544131
31NEK91.42361522
32TTK1.40135296
33TAOK31.39901058
34MAP3K101.34828558
35ZAP701.32929712
36MAPKAPK31.32336784
37KIT1.29929942
38MAP3K81.26004032
39PIM11.24426374
40CDK71.23973734
41CDK41.22978735
42ACVR1B1.21814591
43TYK21.17143999
44ALK1.15974735
45EPHA31.15850358
46BTK1.15595745
47SIK11.14330959
48ERN11.13967228
49BUB11.13291518
50MST1R1.13113381
51BMX1.12916132
52KSR21.12126636
53LRRK21.10302144
54TXK1.10288012
55LATS11.10271366
56TRPM71.02561383
57PLK10.98972533
58FGFR30.96525481
59TGFBR20.96321198
60FGFR40.95773357
61AURKB0.93889213
62EIF2AK10.92444679
63BRD40.92101484
64SRPK10.91157063
65BCKDK0.88604051
66CDK60.88168168
67CHEK10.87488449
68NME20.86966488
69RPS6KA60.82252027
70TAOK10.80662842
71PLK30.78897062
72TEC0.78420718
73MAP3K140.77211063
74ATM0.77099170
75EIF2AK30.76752995
76MAPK110.76298527
77PAK20.75703475
78MTOR0.74174522
79MAP3K50.73593659
80CHUK0.73532389
81CDK80.72414128
82BRAF0.72118520
83MAP3K10.71863133
84CSF1R0.69818132
85BRSK10.69202316
86RPS6KC10.68382694
87RPS6KL10.68382694
88FRK0.68199191
89MAP3K130.67384449
90TBK10.66782219
91TTN0.66369719
92MARK20.66115813
93MELK0.66027346
94CDK20.65163023
95JAK20.64390557
96STK40.63281119
97BMPR20.62744999
98LATS20.61965748
99RPS6KB10.61438176
100PAK40.61251603
101RPS6KA20.60885193
102PTK60.60376089
103EPHA20.60210625
104CHEK20.59846560
105ITK0.58792869
106CCNB10.58420735
107STK240.57462389
108PLK40.56790573
109GRK60.56692262
110PDGFRA0.56601278
111ILK0.56556692
112AURKA0.56519803
113TESK20.55865849
114CDK90.55815907
115LCK0.54713855
116JAK10.54547608
117DYRK30.54307162
118RET0.53385990
119STK30.52211016
120SYK0.51905942
121MAPKAPK20.51012895
122MST40.50273547
123CDK10.49820597
124IKBKB0.49682823
125CLK10.49278134
126MATK0.48958741
127RAF10.47838220
128CAMK1G0.47581608
129MAP3K110.46731574
130ARAF0.45253289
131AKT20.44370558
132MAP2K20.41362972
133PDPK10.40353206
134MET0.39688864
135MAP3K70.39397116
136KSR10.37471691

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.34384037
2Mismatch repair_Homo sapiens_hsa034303.39806034
3One carbon pool by folate_Homo sapiens_hsa006702.99016248
4Base excision repair_Homo sapiens_hsa034102.58384296
5Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.45894851
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.43392530
7Cell cycle_Homo sapiens_hsa041102.30370781
8RNA transport_Homo sapiens_hsa030132.23178217
9Homologous recombination_Homo sapiens_hsa034402.08768869
10Nucleotide excision repair_Homo sapiens_hsa034202.05625740
11Spliceosome_Homo sapiens_hsa030401.90362093
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.80226873
13Non-homologous end-joining_Homo sapiens_hsa034501.58618033
14p53 signaling pathway_Homo sapiens_hsa041151.57348662
15Antigen processing and presentation_Homo sapiens_hsa046121.46546337
16Fanconi anemia pathway_Homo sapiens_hsa034601.45764932
17Biosynthesis of amino acids_Homo sapiens_hsa012301.41135870
18RNA degradation_Homo sapiens_hsa030181.38685745
19Pyrimidine metabolism_Homo sapiens_hsa002401.31846764
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.27408971
21Viral carcinogenesis_Homo sapiens_hsa052031.26331034
22Herpes simplex infection_Homo sapiens_hsa051681.24697592
23Ribosome_Homo sapiens_hsa030101.21021381
24Pentose phosphate pathway_Homo sapiens_hsa000301.18311525
25Thyroid cancer_Homo sapiens_hsa052161.17768215
26Selenocompound metabolism_Homo sapiens_hsa004501.17620687
27Cyanoamino acid metabolism_Homo sapiens_hsa004601.17135214
28Renal cell carcinoma_Homo sapiens_hsa052111.14300830
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.13630820
30Leishmaniasis_Homo sapiens_hsa051401.13431190
31NF-kappa B signaling pathway_Homo sapiens_hsa040641.12912822
32mRNA surveillance pathway_Homo sapiens_hsa030151.12786210
33Measles_Homo sapiens_hsa051621.11890882
34Acute myeloid leukemia_Homo sapiens_hsa052211.11138367
35VEGF signaling pathway_Homo sapiens_hsa043701.08770615
36Epstein-Barr virus infection_Homo sapiens_hsa051691.07062855
37Chronic myeloid leukemia_Homo sapiens_hsa052201.06966976
38Small cell lung cancer_Homo sapiens_hsa052221.05475769
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.03313813
40ErbB signaling pathway_Homo sapiens_hsa040121.01971465
41Prostate cancer_Homo sapiens_hsa052150.99520969
42Adherens junction_Homo sapiens_hsa045200.99246234
43Proteasome_Homo sapiens_hsa030500.99172887
44Primary immunodeficiency_Homo sapiens_hsa053400.98794598
45HTLV-I infection_Homo sapiens_hsa051660.96564951
46Lysine degradation_Homo sapiens_hsa003100.96458790
47Inositol phosphate metabolism_Homo sapiens_hsa005620.94601699
48Apoptosis_Homo sapiens_hsa042100.93179267
49RNA polymerase_Homo sapiens_hsa030200.91089349
50MicroRNAs in cancer_Homo sapiens_hsa052060.91077262
51Systemic lupus erythematosus_Homo sapiens_hsa053220.90492497
52Hepatitis B_Homo sapiens_hsa051610.90150476
53Legionellosis_Homo sapiens_hsa051340.90065035
54Thyroid hormone signaling pathway_Homo sapiens_hsa049190.87704474
55Glioma_Homo sapiens_hsa052140.86037697
56B cell receptor signaling pathway_Homo sapiens_hsa046620.84009161
57Toxoplasmosis_Homo sapiens_hsa051450.82569473
58Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.82052130
59Transcriptional misregulation in cancer_Homo sapiens_hsa052020.81551055
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.79333339
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.78629645
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.78241043
63Hepatitis C_Homo sapiens_hsa051600.78124797
64Pancreatic cancer_Homo sapiens_hsa052120.77112210
65Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.75500685
66Jak-STAT signaling pathway_Homo sapiens_hsa046300.74466260
67Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73583444
68Insulin signaling pathway_Homo sapiens_hsa049100.71718385
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71645666
70Non-small cell lung cancer_Homo sapiens_hsa052230.70209393
71mTOR signaling pathway_Homo sapiens_hsa041500.70014254
72Carbon metabolism_Homo sapiens_hsa012000.69978836
73Fructose and mannose metabolism_Homo sapiens_hsa000510.69372715
74Influenza A_Homo sapiens_hsa051640.69211229
75Oocyte meiosis_Homo sapiens_hsa041140.68269526
76Basal transcription factors_Homo sapiens_hsa030220.68060236
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67990695
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.67724587
79Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.67548096
80Leukocyte transendothelial migration_Homo sapiens_hsa046700.65432096
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.65174607
82TNF signaling pathway_Homo sapiens_hsa046680.64187574
83Alcoholism_Homo sapiens_hsa050340.64126897
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.63849649
85Shigellosis_Homo sapiens_hsa051310.62557601
86Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.62074414
87Prolactin signaling pathway_Homo sapiens_hsa049170.61678068
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60851187
89Colorectal cancer_Homo sapiens_hsa052100.60271694
90Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59315299
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.58861822
92Proteoglycans in cancer_Homo sapiens_hsa052050.58642695
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.58271483
94T cell receptor signaling pathway_Homo sapiens_hsa046600.57960782
95Osteoclast differentiation_Homo sapiens_hsa043800.57656096
96Notch signaling pathway_Homo sapiens_hsa043300.57423186
97Insulin resistance_Homo sapiens_hsa049310.57076147
98Hematopoietic cell lineage_Homo sapiens_hsa046400.57062662
99N-Glycan biosynthesis_Homo sapiens_hsa005100.56850964
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56398059
101HIF-1 signaling pathway_Homo sapiens_hsa040660.56027204
102Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.55651059
103AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.53436395
104Toll-like receptor signaling pathway_Homo sapiens_hsa046200.53251641
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52827999
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52646278
107Platelet activation_Homo sapiens_hsa046110.52392210
108Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52122070
109Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.51966510
110Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.50241816
111Choline metabolism in cancer_Homo sapiens_hsa052310.50080324
112AMPK signaling pathway_Homo sapiens_hsa041520.50037925
113Staphylococcus aureus infection_Homo sapiens_hsa051500.49824072
114Other glycan degradation_Homo sapiens_hsa005110.49292382
115Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49030750
116Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48191897
117Purine metabolism_Homo sapiens_hsa002300.47625084
118Arginine biosynthesis_Homo sapiens_hsa002200.45759541
119Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44829363
120Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.43904537
121Endometrial cancer_Homo sapiens_hsa052130.42731714
122Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.42534754
123Primary bile acid biosynthesis_Homo sapiens_hsa001200.41698187
124Melanoma_Homo sapiens_hsa052180.41125572
125Bladder cancer_Homo sapiens_hsa052190.40952611
126Galactose metabolism_Homo sapiens_hsa000520.40830125
127Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40566381

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