ANKRD29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuronal action potential propagation (GO:0019227)5.71943395
2neuron cell-cell adhesion (GO:0007158)5.13585287
3postsynaptic membrane organization (GO:0001941)5.09881125
4presynaptic membrane assembly (GO:0097105)4.95929994
5vocalization behavior (GO:0071625)4.77170899
6negative regulation of synaptic transmission, GABAergic (GO:0032229)4.74605375
7synaptic vesicle exocytosis (GO:0016079)4.54456594
8positive regulation of triglyceride biosynthetic process (GO:0010867)4.44028061
9regulation of synaptic vesicle exocytosis (GO:2000300)4.41091729
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.40727544
11response to pheromone (GO:0019236)4.37557072
12protein localization to synapse (GO:0035418)4.36919238
13presynaptic membrane organization (GO:0097090)4.35839529
14negative regulation of dendrite morphogenesis (GO:0050774)4.23004285
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.17464780
16regulation of short-term neuronal synaptic plasticity (GO:0048172)4.12688661
17synaptic vesicle maturation (GO:0016188)4.08703920
18neurotransmitter-gated ion channel clustering (GO:0072578)4.03113950
19regulation of triglyceride biosynthetic process (GO:0010866)4.01110305
20glutamate secretion (GO:0014047)3.96671949
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.95822393
22positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003573.92234643
23surfactant homeostasis (GO:0043129)3.91988823
24regulation of glutamate receptor signaling pathway (GO:1900449)3.88938848
25neurofilament cytoskeleton organization (GO:0060052)3.86641164
26mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.83336240
27regulation of triglyceride catabolic process (GO:0010896)3.80561492
28neurotransmitter secretion (GO:0007269)3.79277897
29regulation of synaptic vesicle transport (GO:1902803)3.78803811
30lipid particle organization (GO:0034389)3.64819811
31gamma-aminobutyric acid transport (GO:0015812)3.60963313
32regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.60378714
33cellular response to pH (GO:0071467)3.58908794
34negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.58735301
35transepithelial transport (GO:0070633)3.57789357
36ionotropic glutamate receptor signaling pathway (GO:0035235)3.57678524
37detection of calcium ion (GO:0005513)3.55725662
38chemical homeostasis within a tissue (GO:0048875)3.50672422
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.49356370
40positive regulation of synaptic transmission, GABAergic (GO:0032230)3.45520071
41positive regulation of action potential (GO:0045760)3.43683744
42neuromuscular process controlling posture (GO:0050884)3.42597182
43negative regulation of dendrite development (GO:2000171)3.41169345
44positive regulation of synapse assembly (GO:0051965)3.40979793
45chaperone-mediated protein transport (GO:0072321)3.38791995
46respiratory electron transport chain (GO:0022904)3.34068245
47positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.32766065
48glutamate receptor signaling pathway (GO:0007215)3.31309494
49GTP biosynthetic process (GO:0006183)3.31144083
50mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.30605253
51exploration behavior (GO:0035640)3.30208963
52neuron-neuron synaptic transmission (GO:0007270)3.28679035
53electron transport chain (GO:0022900)3.27673169
54regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.24763080
55regulation of synaptic transmission, GABAergic (GO:0032228)3.24080508
56gamma-aminobutyric acid signaling pathway (GO:0007214)3.23955207
57regulation of alkaline phosphatase activity (GO:0010692)3.20241484
58cell migration involved in sprouting angiogenesis (GO:0002042)3.20237342
59neurotransmitter transport (GO:0006836)3.16622284
60short-term memory (GO:0007614)3.16024012
61regulation of respiratory system process (GO:0044065)3.13399274
62synaptic transmission, glutamatergic (GO:0035249)3.10937754
63calcium-mediated signaling using intracellular calcium source (GO:0035584)3.10936717
64synapse assembly (GO:0007416)3.07157170
65transmission of nerve impulse (GO:0019226)3.04582869
66locomotory exploration behavior (GO:0035641)3.03303861
67cellular response to cholesterol (GO:0071397)3.02231237
68regulation of neuronal synaptic plasticity (GO:0048168)3.00915865
69positive regulation of triglyceride metabolic process (GO:0090208)3.00801278
70positive regulation of neurotransmitter transport (GO:0051590)2.98340847
71proline transport (GO:0015824)2.98306166
72energy coupled proton transport, down electrochemical gradient (GO:0015985)2.96637395
73ATP synthesis coupled proton transport (GO:0015986)2.96637395
74regulation of neurotransmitter levels (GO:0001505)2.96098793
75regulation of long-term neuronal synaptic plasticity (GO:0048169)2.96022601
76positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.93111449
77innervation (GO:0060384)2.92971801
78positive regulation of membrane potential (GO:0045838)2.90874933
79regulation of lipoprotein particle clearance (GO:0010984)2.88623797
80synaptic vesicle docking involved in exocytosis (GO:0016081)2.87346540
81startle response (GO:0001964)2.87030144
82regulation of excitatory postsynaptic membrane potential (GO:0060079)2.86916695
83neuromuscular synaptic transmission (GO:0007274)2.86674779
84cell migration in hindbrain (GO:0021535)2.86472911
85regulation of neurotransmitter secretion (GO:0046928)2.85171686
86striatum development (GO:0021756)2.84203545
87positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.81621060
88membrane assembly (GO:0071709)2.81143832
89metanephric nephron tubule development (GO:0072234)2.80936039
90metanephric tubule development (GO:0072170)2.80936039
91regulation of respiratory gaseous exchange (GO:0043576)2.80923088
92mitochondrial respiratory chain complex I assembly (GO:0032981)2.80422056
93NADH dehydrogenase complex assembly (GO:0010257)2.80422056
94mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.80422056
95response to histamine (GO:0034776)2.80325911
96neuron recognition (GO:0008038)2.79738494
97platelet dense granule organization (GO:0060155)2.79643050
98positive regulation of neurotransmitter secretion (GO:0001956)2.79486125
99peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.79454575
100regulation of synapse assembly (GO:0051963)2.78318076
101positive regulation of vasculogenesis (GO:2001214)2.77431075
102ATP hydrolysis coupled proton transport (GO:0015991)2.77429948
103energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.77429948
104toxin metabolic process (GO:0009404)2.77201727
105hindbrain development (GO:0030902)2.77061980
106mechanosensory behavior (GO:0007638)2.76500523
107membrane depolarization during action potential (GO:0086010)2.76465610
108tonic smooth muscle contraction (GO:0014820)2.75504371
109negative regulation of appetite (GO:0032099)2.74746444
110negative regulation of response to food (GO:0032096)2.74746444
111brain morphogenesis (GO:0048854)2.74506259
112regulation of vasculogenesis (GO:2001212)2.73906368
113regulation of synaptic transmission, glutamatergic (GO:0051966)2.73584244
114response to dietary excess (GO:0002021)2.73283431
115long-term synaptic potentiation (GO:0060291)2.70915898
116regulation of neurotransmitter transport (GO:0051588)2.70176023
117auditory behavior (GO:0031223)2.70050427
118regulation of synapse structural plasticity (GO:0051823)2.68547626
119regulation of vesicle fusion (GO:0031338)2.68155397
120metanephric mesenchyme development (GO:0072075)2.67398439
121synaptic transmission (GO:0007268)2.67175590
122UTP biosynthetic process (GO:0006228)2.66428662
123regulation of postsynaptic membrane potential (GO:0060078)2.65862195
124UTP metabolic process (GO:0046051)2.65567360
125positive regulation of potassium ion transmembrane transport (GO:1901381)2.65234426
126cellular response to sterol (GO:0036315)2.63426000
127artery development (GO:0060840)2.62269416
128righting reflex (GO:0060013)2.62181521
129positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.62170495
130membrane depolarization (GO:0051899)2.62155033
131cerebellar Purkinje cell differentiation (GO:0021702)2.62129495
132positive regulation of protein kinase C signaling (GO:0090037)2.61885041
133smooth muscle tissue development (GO:0048745)2.61360018
134response to auditory stimulus (GO:0010996)2.61052444
135peripheral nervous system neuron development (GO:0048935)2.59646086
136regulation of protein kinase A signaling (GO:0010738)2.59197672
137serotonin receptor signaling pathway (GO:0007210)2.58890464
138regulation of voltage-gated calcium channel activity (GO:1901385)2.58228831
139axon ensheathment in central nervous system (GO:0032291)2.57148800
140central nervous system myelination (GO:0022010)2.57148800
141G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.55450533
142cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.55050298
143adult walking behavior (GO:0007628)2.54469745
144protein-cofactor linkage (GO:0018065)2.53952841
145type B pancreatic cell proliferation (GO:0044342)2.53589188
146protein complex biogenesis (GO:0070271)2.53356866
147action potential (GO:0001508)2.52565905
148urinary tract smooth muscle contraction (GO:0014848)2.52200006
149learning (GO:0007612)2.52171011
150adult behavior (GO:0030534)2.51255493
151artery smooth muscle contraction (GO:0014824)2.50968646
152response to gravity (GO:0009629)2.48092581
153kidney mesenchyme development (GO:0072074)2.46055843
154dendritic spine morphogenesis (GO:0060997)2.45449157
155regulation of triglyceride metabolic process (GO:0090207)2.45078950
156metanephric nephron epithelium development (GO:0072243)2.44123212
157negative regulation of complement activation (GO:0045916)2.43104292
158sequestering of actin monomers (GO:0042989)2.42255128
159neuronal action potential (GO:0019228)2.41003475
160positive regulation of sodium ion transmembrane transport (GO:1902307)2.39961435
161regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640)2.39563388
162inner ear receptor stereocilium organization (GO:0060122)2.38379484
163regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178)2.38237597
164nucleoside diphosphate phosphorylation (GO:0006165)2.37433208
165neurotransmitter catabolic process (GO:0042135)2.37325641
166somite rostral/caudal axis specification (GO:0032525)2.37019983
167positive regulation of phosphatase activity (GO:0010922)2.33278299
168lymphangiogenesis (GO:0001946)2.32409004
169neuron projection extension involved in neuron projection guidance (GO:1902284)2.31219686
170axon extension involved in axon guidance (GO:0048846)2.31219686
171parturition (GO:0007567)2.31162354
172protein heterotrimerization (GO:0070208)2.28261432
173detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.27815092
174amino acid salvage (GO:0043102)2.25569039
175L-methionine salvage (GO:0071267)2.25569039
176L-methionine biosynthetic process (GO:0071265)2.25569039
177regulation of cell communication by electrical coupling (GO:0010649)2.25301142
178vascular smooth muscle contraction (GO:0014829)2.24972445
179cellular response to leptin stimulus (GO:0044320)2.22923983
180response to nitrosative stress (GO:0051409)2.21074657
181inositol phosphate-mediated signaling (GO:0048016)2.18121401
182axonal fasciculation (GO:0007413)2.17861194
183respiratory gaseous exchange (GO:0007585)2.17855422
184metanephric epithelium development (GO:0072207)2.17323627
185negative regulation of protein activation cascade (GO:2000258)2.15389348
186mitochondrial respiratory chain complex assembly (GO:0033108)2.14225906

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.52503622
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.08307663
3GBX2_23144817_ChIP-Seq_PC3_Human4.01333999
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.80795149
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.25203387
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.16416800
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.08695838
8TAF15_26573619_Chip-Seq_HEK293_Human2.92347927
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.72395540
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.68344531
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.68344531
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.68100620
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.61518416
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.58927717
15IGF1R_20145208_ChIP-Seq_DFB_Human2.53718252
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.51452313
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.46035820
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.33088992
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.31090484
20ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30818108
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.21315275
22REST_21632747_ChIP-Seq_MESCs_Mouse2.20720696
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.19242852
24BMI1_23680149_ChIP-Seq_NPCS_Mouse2.10864143
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.10644852
26TRIM28_21343339_ChIP-Seq_HEK293_Human2.09637854
27EZH2_27294783_Chip-Seq_ESCs_Mouse2.03972710
28CTBP2_25329375_ChIP-Seq_LNCAP_Human2.03724773
29SUZ12_27294783_Chip-Seq_ESCs_Mouse2.03236546
30RNF2_27304074_Chip-Seq_ESCs_Mouse2.01206535
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.98865967
32AR_21572438_ChIP-Seq_LNCaP_Human1.96263768
33P300_19829295_ChIP-Seq_ESCs_Human1.88362972
34PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.85747880
35SMAD4_21799915_ChIP-Seq_A2780_Human1.81522174
36PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.79476554
37IKZF1_21737484_ChIP-ChIP_HCT116_Human1.69925834
38REST_18959480_ChIP-ChIP_MESCs_Mouse1.68541596
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.67515022
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.67499051
41CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62084941
42SMAD_19615063_ChIP-ChIP_OVARY_Human1.59074760
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.57932304
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.57556821
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.54621206
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.53244852
47EP300_21415370_ChIP-Seq_HL-1_Mouse1.53170989
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52173179
49ZNF274_21170338_ChIP-Seq_K562_Hela1.50658493
50AR_25329375_ChIP-Seq_VCAP_Human1.49499134
51* CJUN_26792858_Chip-Seq_BT549_Human1.49457420
52RNF2_27304074_Chip-Seq_NSC_Mouse1.49373904
53* PIAS1_25552417_ChIP-Seq_VCAP_Human1.45831177
54* SMAD3_21741376_ChIP-Seq_EPCs_Human1.45205710
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45096381
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44280551
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.43746001
58ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.41935968
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41446618
60CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.40738657
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.39959479
62VDR_22108803_ChIP-Seq_LS180_Human1.36985479
63* AHR_22903824_ChIP-Seq_MCF-7_Human1.36449073
64DROSHA_22980978_ChIP-Seq_HELA_Human1.34489320
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34384762
66CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.33931642
67RARB_27405468_Chip-Seq_BRAIN_Mouse1.29318842
68BCAT_22108803_ChIP-Seq_LS180_Human1.28531391
69SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28382815
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.28256157
71FUS_26573619_Chip-Seq_HEK293_Human1.27507684
72ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25380853
73TP53_18474530_ChIP-ChIP_U2OS_Human1.24822531
74ER_23166858_ChIP-Seq_MCF-7_Human1.24501511
75E2F1_18555785_Chip-Seq_ESCs_Mouse1.22336559
76CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21832085
77PRDM14_20953172_ChIP-Seq_ESCs_Human1.20131368
78HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.19655087
79RARG_19884340_ChIP-ChIP_MEFs_Mouse1.19338225
80P53_22387025_ChIP-Seq_ESCs_Mouse1.18754586
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.17733192
82STAT3_23295773_ChIP-Seq_U87_Human1.16760859
83UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16199608
84TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.15607705
85RUNX2_22187159_ChIP-Seq_PCA_Human1.14424275
86* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.14290910
87JUN_21703547_ChIP-Seq_K562_Human1.13842270
88TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12293483
89CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11849873
90ESR1_21235772_ChIP-Seq_MCF-7_Human1.11566651
91PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.11391649
92* ARNT_22903824_ChIP-Seq_MCF-7_Human1.10561614
93SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09345257
94ERG_21242973_ChIP-ChIP_JURKAT_Human1.07963909
95ETV2_25802403_ChIP-Seq_MESCs_Mouse1.07809546
96CMYC_18555785_Chip-Seq_ESCs_Mouse1.07075662
97ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.07037513
98SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06838109
99MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06709842
100SOX2_21211035_ChIP-Seq_LN229_Gbm1.06571271
101KDM2B_26808549_Chip-Seq_REH_Human1.06134285
102NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.05807499
103NRF2_20460467_ChIP-Seq_MEFs_Mouse1.05807499
104RING1B_27294783_Chip-Seq_ESCs_Mouse1.05630806
105KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05560533
106MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05299179
107TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04919963
108POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04919963
109EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04407306
110FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.02674647
111TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02253178
112P300_18555785_Chip-Seq_ESCs_Mouse1.02141570
113SOX2_18555785_Chip-Seq_ESCs_Mouse1.01526969
114NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01348119
115TCF4_23295773_ChIP-Seq_U87_Human1.00652306
116STAT3_18555785_Chip-Seq_ESCs_Mouse1.00147099
117PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99754579
118BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98805575
119EWS_26573619_Chip-Seq_HEK293_Human0.98711145
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.98633711
121NMYC_18555785_Chip-Seq_ESCs_Mouse0.98544908
122TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97713098
123CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.96975395
124TCF4_22108803_ChIP-Seq_LS180_Human0.96855770
125FOXM1_26456572_ChIP-Seq_MCF-7_Human0.96151593
126NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.95771915
127IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.95122920
128CBP_20019798_ChIP-Seq_JUKART_Human0.95122920
129TP53_16413492_ChIP-PET_HCT116_Human0.94972073
130CDX2_22108803_ChIP-Seq_LS180_Human0.93617870
131STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93150867
132PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.91577152

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.47526373
2MP0000569_abnormal_digit_pigmentation5.23013883
3MP0004859_abnormal_synaptic_plasticity3.80773934
4MP0009046_muscle_twitch3.59450502
5MP0002735_abnormal_chemical_nociception3.39261878
6MP0003635_abnormal_synaptic_transmissio3.28294244
7MP0005503_abnormal_tendon_morphology3.19155941
8MP0001968_abnormal_touch/_nociception3.13413817
9MP0006276_abnormal_autonomic_nervous3.08762131
10MP0004270_analgesia2.98120035
11MP0009745_abnormal_behavioral_response2.97777767
12MP0002064_seizures2.81198702
13MP0002736_abnormal_nociception_after2.78134434
14MP0002734_abnormal_mechanical_nocicepti2.63429468
15MP0002272_abnormal_nervous_system2.53978416
16MP0002063_abnormal_learning/memory/cond2.47440509
17MP0009379_abnormal_foot_pigmentation2.46819364
18MP0002572_abnormal_emotion/affect_behav2.44397595
19MP0001486_abnormal_startle_reflex2.43355645
20MP0001188_hyperpigmentation2.40116642
21MP0001958_emphysema2.38836601
22MP0002067_abnormal_sensory_capabilities2.25078602
23MP0001501_abnormal_sleep_pattern2.23380300
24MP0003283_abnormal_digestive_organ2.20074506
25MP0005275_abnormal_skin_tensile2.17616586
26MP0002733_abnormal_thermal_nociception2.15266488
27MP0003950_abnormal_plasma_membrane2.10939911
28MP0001970_abnormal_pain_threshold2.08834406
29MP0001986_abnormal_taste_sensitivity2.03096341
30MP0002184_abnormal_innervation1.94950600
31MP0008569_lethality_at_weaning1.92111130
32MP0008438_abnormal_cutaneous_collagen1.91457576
33MP0001440_abnormal_grooming_behavior1.85388013
34MP0001542_abnormal_bone_strength1.85343091
35MP0004142_abnormal_muscle_tone1.84434036
36MP0002557_abnormal_social/conspecific_i1.84142146
37MP0005084_abnormal_gallbladder_morpholo1.83898990
38MP0010368_abnormal_lymphatic_system1.82762023
39MP0002876_abnormal_thyroid_physiology1.78926833
40MP0004858_abnormal_nervous_system1.77802940
41MP0002822_catalepsy1.69819967
42MP0004782_abnormal_surfactant_physiolog1.62871861
43MP0005595_abnormal_vascular_smooth1.54836146
44MP0005386_behavior/neurological_phenoty1.53865377
45MP0004924_abnormal_behavior1.53865377
46MP0001905_abnormal_dopamine_level1.52166713
47MP0005409_darkened_coat_color1.51545991
48MP0000778_abnormal_nervous_system1.49405214
49MP0001984_abnormal_olfaction1.49361536
50MP0002295_abnormal_pulmonary_circulatio1.44829062
51MP0005646_abnormal_pituitary_gland1.43596404
52MP0002139_abnormal_hepatobiliary_system1.43295784
53MP0003136_yellow_coat_color1.42099424
54MP0004043_abnormal_pH_regulation1.40497172
55MP0003879_abnormal_hair_cell1.39456895
56MP0001346_abnormal_lacrimal_gland1.39175091
57MP0005423_abnormal_somatic_nervous1.38462365
58MP0003011_delayed_dark_adaptation1.34384269
59MP0001529_abnormal_vocalization1.33363975
60MP0003646_muscle_fatigue1.31887670
61MP0002638_abnormal_pupillary_reflex1.30556255
62MP0000955_abnormal_spinal_cord1.30534138
63MP0005670_abnormal_white_adipose1.28710261
64MP0010030_abnormal_orbit_morphology1.26497616
65MP0004811_abnormal_neuron_physiology1.25444595
66MP0005645_abnormal_hypothalamus_physiol1.25008030
67MP0002882_abnormal_neuron_morphology1.24953085
68MP0001879_abnormal_lymphatic_vessel1.23748823
69MP0002066_abnormal_motor_capabilities/c1.21576644
70MP0002751_abnormal_autonomic_nervous1.21057923
71MP0005085_abnormal_gallbladder_physiolo1.20626672
72MP0004215_abnormal_myocardial_fiber1.20013146
73MP0003122_maternal_imprinting1.18997161
74MP0000230_abnormal_systemic_arterial1.17163338
75MP0000751_myopathy1.15919689
76MP0001963_abnormal_hearing_physiology1.15893314
77MP0005360_urolithiasis1.13271283
78MP0001502_abnormal_circadian_rhythm1.09836715
79MP0005332_abnormal_amino_acid1.08652352
80MP0005620_abnormal_muscle_contractility1.07977957
81MP0005508_abnormal_skeleton_morphology1.07906038
82MP0002332_abnormal_exercise_endurance1.07621840
83MP0003252_abnormal_bile_duct1.07145071
84MP0006292_abnormal_olfactory_placode1.04527692
85MP0010386_abnormal_urinary_bladder1.03144784
86MP0004272_abnormal_basement_membrane1.02738277
87MP0001485_abnormal_pinna_reflex1.02230126
88MP0002102_abnormal_ear_morphology1.00419026
89MP0002928_abnormal_bile_duct0.99847803
90MP0000026_abnormal_inner_ear0.98313697
91MP0005365_abnormal_bile_salt0.98173473
92MP0002938_white_spotting0.96559524
93MP0004484_altered_response_of0.96484477
94MP0003633_abnormal_nervous_system0.95718356
95MP0000372_irregular_coat_pigmentation0.95638441
96MP0005164_abnormal_response_to0.95578346
97MP0002837_dystrophic_cardiac_calcinosis0.94908065
98MP0002282_abnormal_trachea_morphology0.94800629
99MP0003787_abnormal_imprinting0.93749567
100MP0003195_calcinosis0.93690866
101MP0002108_abnormal_muscle_morphology0.93609660
102MP0003938_abnormal_ear_development0.91996692
103MP0001348_abnormal_lacrimal_gland0.90886971
104MP0001299_abnormal_eye_distance/0.90358393
105MP0002752_abnormal_somatic_nervous0.90312055
106MP0008875_abnormal_xenobiotic_pharmacok0.89577231
107MP0000427_abnormal_hair_cycle0.89120090
108MP0000681_abnormal_thyroid_gland0.88487153
109MP0008995_early_reproductive_senescence0.88253252
110MP0004742_abnormal_vestibular_system0.87373479
111MP0010329_abnormal_lipoprotein_level0.87028126
112MP0001270_distended_abdomen0.86973719
113MP0000383_abnormal_hair_follicle0.86935176
114MP0004133_heterotaxia0.86747500
115MP0005171_absent_coat_pigmentation0.85153861
116MP0003329_amyloid_beta_deposits0.84914640
117MP0003937_abnormal_limbs/digits/tail_de0.84697301
118MP0002909_abnormal_adrenal_gland0.82287962
119MP0003868_abnormal_feces_composition0.82245832
120MP0002229_neurodegeneration0.82171782
121MP0002009_preneoplasia0.81810535
122MP0000013_abnormal_adipose_tissue0.81174700
123MP0005499_abnormal_olfactory_system0.81129325
124MP0005394_taste/olfaction_phenotype0.81129325
125MP0000631_abnormal_neuroendocrine_gland0.79608688
126MP0002152_abnormal_brain_morphology0.78714568
127MP0009250_abnormal_appendicular_skeleto0.78551461
128MP0004883_abnormal_blood_vessel0.77283787
129MP0004885_abnormal_endolymph0.77243581
130MP0002234_abnormal_pharynx_morphology0.76645491
131MP0000049_abnormal_middle_ear0.76188928
132MP0008961_abnormal_basal_metabolism0.75478186
133MP0004145_abnormal_muscle_electrophysio0.75394115
134MP0001756_abnormal_urination0.74810454
135MP0003137_abnormal_impulse_conducting0.74773988
136MP0005187_abnormal_penis_morphology0.74630818
137MP0002069_abnormal_eating/drinking_beha0.74288261
138MP0001664_abnormal_digestion0.73116901
139MP0008775_abnormal_heart_ventricle0.72778820
140MP0010678_abnormal_skin_adnexa0.72714385
141MP0008872_abnormal_physiological_respon0.72459477
142MP0003183_abnormal_peptide_metabolism0.72267948
143MP0004085_abnormal_heartbeat0.72155100
144MP0005535_abnormal_body_temperature0.71537798
145MP0009780_abnormal_chondrocyte_physiolo0.71456438
146MP0008260_abnormal_autophagy0.70616202
147MP0003631_nervous_system_phenotype0.70457957
148MP0004147_increased_porphyrin_level0.69929388
149MP0008874_decreased_physiological_sensi0.65349607
150MP0000566_synostosis0.63777037
151MP0008789_abnormal_olfactory_epithelium0.63441913
152MP0001943_abnormal_respiration0.61682349
153MP0003634_abnormal_glial_cell0.60970194
154MP0005551_abnormal_eye_electrophysiolog0.60898700

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.69664660
2Myokymia (HP:0002411)5.96996867
3Febrile seizures (HP:0002373)5.81986257
4Atonic seizures (HP:0010819)5.72032491
5Focal seizures (HP:0007359)4.46052619
6Hypothermia (HP:0002045)4.41228795
7Neuroendocrine neoplasm (HP:0100634)4.18856425
8Epileptic encephalopathy (HP:0200134)4.15127758
9Pheochromocytoma (HP:0002666)4.08602199
10Acute necrotizing encephalopathy (HP:0006965)4.05990604
11Absence seizures (HP:0002121)3.98499974
12Progressive cerebellar ataxia (HP:0002073)3.89569278
13Mitochondrial inheritance (HP:0001427)3.77615779
14Progressive macrocephaly (HP:0004481)3.76963350
15Abnormal mitochondria in muscle tissue (HP:0008316)3.74939732
16Hepatocellular necrosis (HP:0001404)3.62420296
17Action tremor (HP:0002345)3.53066375
18Dialeptic seizures (HP:0011146)3.53031837
19Decreased circulating renin level (HP:0003351)3.41733493
20Abnormality of midbrain morphology (HP:0002418)3.21876500
21Molar tooth sign on MRI (HP:0002419)3.21876500
22Visual hallucinations (HP:0002367)3.19794636
23Progressive inability to walk (HP:0002505)3.15462487
24Ulnar claw (HP:0001178)3.14545421
25Generalized tonic-clonic seizures (HP:0002069)3.14029280
26Neurofibrillary tangles (HP:0002185)3.12869209
27Acute encephalopathy (HP:0006846)3.10095007
28Hyperventilation (HP:0002883)3.06884631
29Increased CSF lactate (HP:0002490)3.06508182
30Optic disc pallor (HP:0000543)2.91775044
31Interstitial pulmonary disease (HP:0006530)2.89715024
32Limb dystonia (HP:0002451)2.88108981
33Congenital, generalized hypertrichosis (HP:0004540)2.84184589
34Poor suck (HP:0002033)2.83443471
35Global brain atrophy (HP:0002283)2.81266834
36Medial flaring of the eyebrow (HP:0010747)2.77209215
37Anxiety (HP:0000739)2.76919986
38Gaze-evoked nystagmus (HP:0000640)2.74455067
39Gait imbalance (HP:0002141)2.74252197
40Neoplasm of the peripheral nervous system (HP:0100007)2.73432594
41Hydroxyprolinuria (HP:0003080)2.68967064
42Abnormality of proline metabolism (HP:0010907)2.68967064
43Hepatic necrosis (HP:0002605)2.62505315
44Tachypnea (HP:0002789)2.56756480
45Pancreatic fibrosis (HP:0100732)2.56391891
46Abnormal eating behavior (HP:0100738)2.55916037
47Congenital primary aphakia (HP:0007707)2.54183077
48Diplopia (HP:0000651)2.51732306
49Abnormality of binocular vision (HP:0011514)2.51732306
50Broad-based gait (HP:0002136)2.48956300
51Nephrogenic diabetes insipidus (HP:0009806)2.47071733
52Depression (HP:0000716)2.46965582
53Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.45312089
54Abnormal hair whorl (HP:0010721)2.43580811
55Atrioventricular block (HP:0001678)2.43274196
56Fetal akinesia sequence (HP:0001989)2.41702471
57Tubulointerstitial fibrosis (HP:0005576)2.38505024
58Delayed CNS myelination (HP:0002188)2.36381171
59Amblyopia (HP:0000646)2.36313265
60Respiratory distress (HP:0002098)2.31384482
61Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.29412858
62Genital tract atresia (HP:0001827)2.28220188
63True hermaphroditism (HP:0010459)2.22599323
64Scanning speech (HP:0002168)2.21024060
65Abnormal atrioventricular conduction (HP:0005150)2.19347905
66Keratoconus (HP:0000563)2.18605407
67Increased corneal curvature (HP:0100692)2.18605407
68Vaginal atresia (HP:0000148)2.18357920
69Clumsiness (HP:0002312)2.15876453
70Exercise intolerance (HP:0003546)2.15663759
71Exertional dyspnea (HP:0002875)2.14037401
72Heart block (HP:0012722)2.13761450
73Pancreatic cysts (HP:0001737)2.13083206
74Bradycardia (HP:0001662)2.11588200
75Thyroid-stimulating hormone excess (HP:0002925)2.11533123
76Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.10584408
77Abnormality of alanine metabolism (HP:0010916)2.10584408
78Hyperalaninemia (HP:0003348)2.10584408
79X-linked dominant inheritance (HP:0001423)2.09276458
80Hemiparesis (HP:0001269)2.08203607
81Inability to walk (HP:0002540)2.06784640
82Progressive external ophthalmoplegia (HP:0000590)2.02932831
83Respiratory failure (HP:0002878)2.02683607
84Dysdiadochokinesis (HP:0002075)2.02405516
85Skin nodule (HP:0200036)2.01933109
86Abnormality of glutamine family amino acid metabolism (HP:0010902)2.01741173
87Bundle branch block (HP:0011710)2.01703371
88Nonprogressive disorder (HP:0003680)2.01323853
89Excessive salivation (HP:0003781)2.00505925
90Drooling (HP:0002307)2.00505925
91Prolonged QT interval (HP:0001657)2.00237730
92Polyphagia (HP:0002591)1.99124618
93Nephronophthisis (HP:0000090)1.98688805
94Bone cyst (HP:0012062)1.98500377
95Aortic aneurysm (HP:0004942)1.98478638
96Specific learning disability (HP:0001328)1.97629620
97Truncal ataxia (HP:0002078)1.96277975
98Hyperaldosteronism (HP:0000859)1.95710066
99Hypoventilation (HP:0002791)1.95377921
100Emotional lability (HP:0000712)1.93909682
101Atrial fibrillation (HP:0005110)1.93337681
102Steppage gait (HP:0003376)1.93245596
103Lactic acidosis (HP:0003128)1.92387181
104Increased hepatocellular lipid droplets (HP:0006565)1.91795518
105Failure to thrive in infancy (HP:0001531)1.91750211
106Hemiplegia (HP:0002301)1.90396718
107Abnormality of the vertebral endplates (HP:0005106)1.90185146
108Abnormality of the vocal cords (HP:0008777)1.89327185
109Dysmetria (HP:0001310)1.89143145
110Increased serum lactate (HP:0002151)1.88978065
111Esotropia (HP:0000565)1.88521913
112Cortical visual impairment (HP:0100704)1.87548299
113Ventricular fibrillation (HP:0001663)1.87543132
114Type II lissencephaly (HP:0007260)1.86833897
115Cystic liver disease (HP:0006706)1.85313549
116Primary atrial arrhythmia (HP:0001692)1.85240608
117Retinal dysplasia (HP:0007973)1.84943415
118Fair hair (HP:0002286)1.84850753
119Agitation (HP:0000713)1.84278190
120Megalencephaly (HP:0001355)1.83449697
121Absent speech (HP:0001344)1.82942621
122Hypercalciuria (HP:0002150)1.82652966
123Short tibia (HP:0005736)1.82635994
124Generalized myoclonic seizures (HP:0002123)1.81639112
125Metabolic alkalosis (HP:0200114)1.80811513
126Prominent supraorbital ridges (HP:0000336)1.80129272
127Hypercortisolism (HP:0001578)1.80073488
128Status epilepticus (HP:0002133)1.79418064
129Blue irides (HP:0000635)1.78980145
130Bilateral microphthalmos (HP:0007633)1.78625607
131Supraventricular tachycardia (HP:0004755)1.77511220
132Cerebral inclusion bodies (HP:0100314)1.77306304
133Intention tremor (HP:0002080)1.77207339
134Vascular tortuosity (HP:0004948)1.77041517
135Severe muscular hypotonia (HP:0006829)1.75729192
136Increased serum pyruvate (HP:0003542)1.75645542
137Abnormality of glycolysis (HP:0004366)1.75645542
138Poor eye contact (HP:0000817)1.73597127
139Cerebral edema (HP:0002181)1.73592907
140Aplasia/Hypoplasia of the tibia (HP:0005772)1.73537520
141Mutism (HP:0002300)1.73068833
142Myotonia (HP:0002486)1.71655668
143Supraventricular arrhythmia (HP:0005115)1.71524336
144Impaired social interactions (HP:0000735)1.71163134
145Abnormal social behavior (HP:0012433)1.71163134
146Irregular vertebral endplates (HP:0003301)1.70719951
147Aplasia/Hypoplasia of the lens (HP:0008063)1.69313394
148Delayed gross motor development (HP:0002194)1.68010713
149Fibular hypoplasia (HP:0003038)1.67579835
150Abnormality of the axillary hair (HP:0100134)1.67285537
151Abnormality of secondary sexual hair (HP:0009888)1.67285537
152Amelogenesis imperfecta (HP:0000705)1.66303977
153Abnormality of dental color (HP:0011073)1.65946572
154Generalized aminoaciduria (HP:0002909)1.65770446
155Abnormality of the renal medulla (HP:0100957)1.65703398
156Redundant skin (HP:0001582)1.64874576
157Renal Fanconi syndrome (HP:0001994)1.63972138
158Epidermoid cyst (HP:0200040)1.63669113
159Hypoplastic toenails (HP:0001800)1.63620350
160Congenital stationary night blindness (HP:0007642)1.63343467
161Abnormality of renin-angiotensin system (HP:0000847)1.63248223
162Cerebellar dysplasia (HP:0007033)1.60201721
163Pulmonary artery stenosis (HP:0004415)1.59230311

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.24512329
2NTRK34.09640240
3MAP3K124.00875567
4MAP2K73.38858144
5TNIK2.82706775
6MINK12.74281445
7MST1R2.73469139
8MAP3K42.61218037
9EPHA42.20612649
10MUSK2.07902797
11STK382.06858839
12GRK51.92297936
13EPHB21.91049665
14MAP3K91.85420239
15MET1.85038258
16ABL21.83816289
17CDK191.74752754
18MAP2K41.68725976
19LMTK21.63514412
20MAPK131.60439755
21GRK71.57769656
22PRPF4B1.55976540
23PAK31.55537892
24TSSK61.45751356
25PLK21.44597757
26ZAK1.37515842
27MARK11.34729888
28SGK21.30530102
29PIM21.28194832
30TNK21.24320623
31DAPK21.24173436
32PRKD21.18189863
33CAMK2A1.16406554
34CSNK1G11.16024485
35TESK11.15730638
36PRKCG1.14278796
37FRK1.13930687
38SGK2231.11675167
39SGK4941.11675167
40MAP4K21.11641940
41TIE11.11630620
42STK391.11442305
43WNK41.09934728
44NTRK11.09635971
45CAMKK21.09542234
46CSNK1G31.09084017
47ARAF1.08149416
48PHKG11.07751009
49PHKG21.07751009
50ERBB31.06983926
51RIPK41.05315559
52NTRK21.03607662
53CSNK1A1L1.00354193
54OXSR11.00005432
55DYRK20.97109077
56CDK50.96932985
57SIK30.94065060
58WNK10.93842488
59BMPR20.93482767
60PRKCE0.93125323
61NME10.92938829
62CAMK2B0.92549636
63ADRBK10.91951748
64MKNK20.91449813
65PKN10.89276275
66LIMK10.86314363
67DMPK0.86113044
68PNCK0.85978376
69MYLK0.84603797
70YES10.84381151
71UHMK10.82603294
72FES0.82494761
73BMPR1B0.77470112
74TESK20.77419024
75RAF10.76710586
76DAPK10.76520036
77MAPK150.74010050
78CAMKK10.72107591
79PDK20.71322301
80STK110.70580321
81CAMK2G0.69830305
82MAP3K110.68839564
83MAPKAPK30.68602731
84ADRBK20.68470138
85MAPKAPK50.67619179
86WNK30.66974359
87DDR20.66682911
88EPHA20.62635978
89PRKACB0.59869959
90ROCK10.59408231
91CDK140.58362009
92INSRR0.58023207
93AKT30.57949745
94PRKG10.57916927
95MST40.57019722
96PTK2B0.56896109
97HIPK20.56657331
98PAK20.56068032
99CAMK10.55938670
100CAMK2D0.55873143
101PAK60.55817302
102FGR0.55674981
103FER0.55643486
104IRAK10.55366566
105PINK10.55024108
106GSK3A0.54690590
107EIF2AK30.54373070
108KSR10.54355105
109EIF2AK20.54290692
110NEK90.54058973
111STK240.53787854
112NLK0.51463344
113CDK80.51203476
114KSR20.50927533
115CDK180.50475115
116DAPK30.49754559
117PRKCI0.49665326
118TGFBR10.49545193
119FGFR20.49080608
120ERBB40.47805394
121CDK30.47289768
122PRKACA0.46961519
123LATS10.46674904
124DYRK1A0.46147929
125IRAK30.46034631
126NEK20.45186202
127BCR0.44510695
128MAP2K10.43675734
129CDK150.43210701
130SGK30.42708278
131RPS6KA50.41876259
132TGFBR20.41386281
133MAP3K130.41357764
134GRK60.41021641
135GRK10.39716644
136RPS6KA20.38203744
137CDK11A0.37426808
138SGK10.36376315
139MAP3K10.36259011
140CSNK1G20.34362467
141IRAK20.34165550
142TLK10.32530271
143SIK20.31609405
144LATS20.30893985
145TAOK20.29799906
146MAP3K20.29548769

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.80148627
2Oxidative phosphorylation_Homo sapiens_hsa001903.49714050
3Synaptic vesicle cycle_Homo sapiens_hsa047213.30629915
4Parkinsons disease_Homo sapiens_hsa050122.80450746
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.63748550
6Linoleic acid metabolism_Homo sapiens_hsa005912.54227090
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.50954375
8Collecting duct acid secretion_Homo sapiens_hsa049662.50594930
9Alzheimers disease_Homo sapiens_hsa050102.44088321
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.42432095
11Phenylalanine metabolism_Homo sapiens_hsa003602.38793383
12Olfactory transduction_Homo sapiens_hsa047402.38728410
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.38367507
14GABAergic synapse_Homo sapiens_hsa047272.38082947
15Taste transduction_Homo sapiens_hsa047422.18941638
16Circadian entrainment_Homo sapiens_hsa047132.14143048
17Long-term potentiation_Homo sapiens_hsa047202.13002235
18Morphine addiction_Homo sapiens_hsa050322.09411450
19Amphetamine addiction_Homo sapiens_hsa050312.06446276
20Dopaminergic synapse_Homo sapiens_hsa047282.04844918
21Glutamatergic synapse_Homo sapiens_hsa047242.04272206
22Huntingtons disease_Homo sapiens_hsa050161.98323134
23Primary bile acid biosynthesis_Homo sapiens_hsa001201.94671556
24Tryptophan metabolism_Homo sapiens_hsa003801.89483749
25Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.87139887
26Salivary secretion_Homo sapiens_hsa049701.80511628
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.80331428
28Histidine metabolism_Homo sapiens_hsa003401.79069738
29Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.77520245
30Cardiac muscle contraction_Homo sapiens_hsa042601.77374447
31Serotonergic synapse_Homo sapiens_hsa047261.74685636
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.71248446
33Long-term depression_Homo sapiens_hsa047301.70416855
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.66471229
35Vibrio cholerae infection_Homo sapiens_hsa051101.62179189
36Cholinergic synapse_Homo sapiens_hsa047251.61069065
37Tyrosine metabolism_Homo sapiens_hsa003501.55986125
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.54604307
39Sulfur metabolism_Homo sapiens_hsa009201.46530745
40Calcium signaling pathway_Homo sapiens_hsa040201.45510825
41Circadian rhythm_Homo sapiens_hsa047101.43103024
42Insulin secretion_Homo sapiens_hsa049111.42629013
43beta-Alanine metabolism_Homo sapiens_hsa004101.42153861
44Nitrogen metabolism_Homo sapiens_hsa009101.42146625
45Gastric acid secretion_Homo sapiens_hsa049711.40333748
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.34470348
47Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.30191862
48Renin secretion_Homo sapiens_hsa049241.30082854
49Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.28941134
50Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25521619
51Cocaine addiction_Homo sapiens_hsa050301.21537361
52Selenocompound metabolism_Homo sapiens_hsa004501.21222993
53Butanoate metabolism_Homo sapiens_hsa006501.20789941
54Chemical carcinogenesis_Homo sapiens_hsa052041.19511461
55Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16676223
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.16272488
57Propanoate metabolism_Homo sapiens_hsa006401.15218372
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.14617601
59Arachidonic acid metabolism_Homo sapiens_hsa005901.14333511
60Retinol metabolism_Homo sapiens_hsa008301.12588190
61Mineral absorption_Homo sapiens_hsa049781.11468818
62Melanogenesis_Homo sapiens_hsa049161.11028040
63PPAR signaling pathway_Homo sapiens_hsa033201.10140147
64Phototransduction_Homo sapiens_hsa047441.07377306
65Oxytocin signaling pathway_Homo sapiens_hsa049211.07100565
66Cyanoamino acid metabolism_Homo sapiens_hsa004601.05440184
67Gap junction_Homo sapiens_hsa045401.05313570
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02889279
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.02711780
70GnRH signaling pathway_Homo sapiens_hsa049120.98981210
71Caffeine metabolism_Homo sapiens_hsa002320.97557181
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.95700703
73Ovarian steroidogenesis_Homo sapiens_hsa049130.94513229
74Bile secretion_Homo sapiens_hsa049760.93669291
75Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.92779775
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91000768
77Fatty acid degradation_Homo sapiens_hsa000710.90828186
78cAMP signaling pathway_Homo sapiens_hsa040240.87774732
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87268579
80Fat digestion and absorption_Homo sapiens_hsa049750.85286093
81Fatty acid elongation_Homo sapiens_hsa000620.85282378
82Pentose and glucuronate interconversions_Homo sapiens_hsa000400.83326594
83Complement and coagulation cascades_Homo sapiens_hsa046100.82272631
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.82149158
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.80435004
86Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.79967630
87Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.79707555
88Rheumatoid arthritis_Homo sapiens_hsa053230.77867450
89ECM-receptor interaction_Homo sapiens_hsa045120.77376763
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77187919
91Axon guidance_Homo sapiens_hsa043600.76689411
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.74088246
93SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73038443
94Vascular smooth muscle contraction_Homo sapiens_hsa042700.71886474
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71535987
96ErbB signaling pathway_Homo sapiens_hsa040120.66368537
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.65070963
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.63916875
99Pancreatic secretion_Homo sapiens_hsa049720.63555193
100Type I diabetes mellitus_Homo sapiens_hsa049400.62922355
101Thyroid cancer_Homo sapiens_hsa052160.62362671
102Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57108961
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56623889
104Steroid biosynthesis_Homo sapiens_hsa001000.56559409
105Glycerolipid metabolism_Homo sapiens_hsa005610.56480123
106Arginine and proline metabolism_Homo sapiens_hsa003300.55773962
107Estrogen signaling pathway_Homo sapiens_hsa049150.55747261
108Phagosome_Homo sapiens_hsa041450.55535074
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.53991075
110Ribosome_Homo sapiens_hsa030100.53193094
111RNA polymerase_Homo sapiens_hsa030200.53009935
112Thyroid hormone synthesis_Homo sapiens_hsa049180.53001541
113Oocyte meiosis_Homo sapiens_hsa041140.52235733
114Wnt signaling pathway_Homo sapiens_hsa043100.50887762
115Choline metabolism in cancer_Homo sapiens_hsa052310.50012308
116Ras signaling pathway_Homo sapiens_hsa040140.46877562
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.45380684
118Pyruvate metabolism_Homo sapiens_hsa006200.45103560
119Basal transcription factors_Homo sapiens_hsa030220.44647994
120Glioma_Homo sapiens_hsa052140.44631915
121Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.43734687
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.43671521
123Metabolic pathways_Homo sapiens_hsa011000.42541060
124ABC transporters_Homo sapiens_hsa020100.42146150
125Peroxisome_Homo sapiens_hsa041460.39309492
126Tight junction_Homo sapiens_hsa045300.39181034
127Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39134725
128MAPK signaling pathway_Homo sapiens_hsa040100.38854956
129Inositol phosphate metabolism_Homo sapiens_hsa005620.38132761
130Dilated cardiomyopathy_Homo sapiens_hsa054140.36839786
131Melanoma_Homo sapiens_hsa052180.36730213
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35672919
133Protein digestion and absorption_Homo sapiens_hsa049740.35584174
134Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.31729804
135Glucagon signaling pathway_Homo sapiens_hsa049220.30406046
136Neurotrophin signaling pathway_Homo sapiens_hsa047220.30181414
137Sphingolipid metabolism_Homo sapiens_hsa006000.29336876
138Alcoholism_Homo sapiens_hsa050340.29254980
139Rap1 signaling pathway_Homo sapiens_hsa040150.28895164
140African trypanosomiasis_Homo sapiens_hsa051430.27697235
141Ether lipid metabolism_Homo sapiens_hsa005650.27512964
142Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.26405497
143Dorso-ventral axis formation_Homo sapiens_hsa043200.24272016
144Hedgehog signaling pathway_Homo sapiens_hsa043400.24178760
145Endometrial cancer_Homo sapiens_hsa052130.22778061
146Protein export_Homo sapiens_hsa030600.21678887
147Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.15318839
148Insulin signaling pathway_Homo sapiens_hsa049100.14479684
149Endocytosis_Homo sapiens_hsa041440.14386061
150Colorectal cancer_Homo sapiens_hsa052100.12891728
151Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.12513161

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