ANKRD36BP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.47251656
2viral transcription (GO:0019083)6.22591289
3establishment of protein localization to mitochondrial membrane (GO:0090151)6.11034805
4translational termination (GO:0006415)6.00094180
5sequestering of actin monomers (GO:0042989)5.60264522
6energy coupled proton transport, down electrochemical gradient (GO:0015985)5.59169730
7ATP synthesis coupled proton transport (GO:0015986)5.59169730
8cotranslational protein targeting to membrane (GO:0006613)5.42128846
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.40280065
10protein targeting to ER (GO:0045047)5.31075355
11establishment of protein localization to endoplasmic reticulum (GO:0072599)5.10870162
12protein localization to endoplasmic reticulum (GO:0070972)4.88536488
13translational elongation (GO:0006414)4.80253391
14neuron fate determination (GO:0048664)4.70116375
15limb bud formation (GO:0060174)4.65299566
16cellular protein complex disassembly (GO:0043624)4.57253661
17mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.56913203
18ribosomal small subunit assembly (GO:0000028)4.49743039
19epithelial cilium movement (GO:0003351)4.48144848
20respiratory electron transport chain (GO:0022904)4.38465077
21electron transport chain (GO:0022900)4.32626047
22midbrain development (GO:0030901)4.32328532
23viral life cycle (GO:0019058)4.26915661
24nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.21531898
25behavioral response to nicotine (GO:0035095)4.14887748
26otic vesicle formation (GO:0030916)4.11992220
27inner mitochondrial membrane organization (GO:0007007)4.11226646
28lateral sprouting from an epithelium (GO:0060601)4.05428791
29translational initiation (GO:0006413)3.93890553
30intraciliary transport (GO:0042073)3.93464812
31positive regulation of gastrulation (GO:2000543)3.76763372
32cilium movement (GO:0003341)3.75788894
33dopaminergic neuron differentiation (GO:0071542)3.75600509
34centriole replication (GO:0007099)3.75549880
35protein complex disassembly (GO:0043241)3.72637825
36primitive streak formation (GO:0090009)3.66787021
37epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.62241385
38presynaptic membrane assembly (GO:0097105)3.60991079
39protein localization to cilium (GO:0061512)3.57657252
40macromolecular complex disassembly (GO:0032984)3.56834079
41somite development (GO:0061053)3.54013973
42protein complex biogenesis (GO:0070271)3.52230090
43neuronal stem cell maintenance (GO:0097150)3.49765556
44mitochondrial respiratory chain complex I assembly (GO:0032981)3.47798693
45NADH dehydrogenase complex assembly (GO:0010257)3.47798693
46mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.47798693
47protein targeting to membrane (GO:0006612)3.47582830
48neural tube formation (GO:0001841)3.42309248
49protein neddylation (GO:0045116)3.33936825
50proteasome assembly (GO:0043248)3.32091074
51maturation of SSU-rRNA (GO:0030490)3.26658783
52mitochondrial respiratory chain complex assembly (GO:0033108)3.26557913
53retinal ganglion cell axon guidance (GO:0031290)3.23361084
54ribosomal large subunit biogenesis (GO:0042273)3.23181072
55detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.21252937
56regulation of timing of cell differentiation (GO:0048505)3.20684074
57presynaptic membrane organization (GO:0097090)3.18717815
58axonemal dynein complex assembly (GO:0070286)3.15058972
59nuclear-transcribed mRNA catabolic process (GO:0000956)3.07825797
60hydrogen ion transmembrane transport (GO:1902600)3.04722354
61DNA damage response, detection of DNA damage (GO:0042769)3.00483243
62neuron cell-cell adhesion (GO:0007158)2.94900655
63somite rostral/caudal axis specification (GO:0032525)2.92817754
64mRNA catabolic process (GO:0006402)2.91161285
65regulation of development, heterochronic (GO:0040034)2.88314542
66smoothened signaling pathway (GO:0007224)2.84013533
67negative regulation of axon guidance (GO:1902668)2.80420762
68forebrain neuron differentiation (GO:0021879)2.79779574
69proton transport (GO:0015992)2.79477066
70translation (GO:0006412)2.79444135
71ATP biosynthetic process (GO:0006754)2.77334883
72ventricular system development (GO:0021591)2.76368859
73platelet dense granule organization (GO:0060155)2.76068514
74ribosomal small subunit biogenesis (GO:0042274)2.75162040
75hydrogen transport (GO:0006818)2.74176559
76purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.71725005
77cilium morphogenesis (GO:0060271)2.70950493
78negative regulation of oligodendrocyte differentiation (GO:0048715)2.70382429
79purine nucleoside triphosphate biosynthetic process (GO:0009145)2.69208593
80positive regulation of embryonic development (GO:0040019)2.66060234
81postsynaptic membrane organization (GO:0001941)2.65744624
82kidney morphogenesis (GO:0060993)2.65334094
83spinal cord motor neuron differentiation (GO:0021522)2.64738151
84chaperone-mediated protein transport (GO:0072321)2.62052381
85tongue development (GO:0043586)2.60124872
86hindbrain development (GO:0030902)2.57572301
87organelle disassembly (GO:1903008)2.56521501
88determination of left/right symmetry (GO:0007368)2.54860629
89GTP biosynthetic process (GO:0006183)2.53960390
90cilium organization (GO:0044782)2.53182819
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.53144155
92RNA catabolic process (GO:0006401)2.51928919
93intracellular protein transmembrane import (GO:0044743)2.51607994
94negative regulation of glial cell differentiation (GO:0045686)2.51250106
95regulation of non-canonical Wnt signaling pathway (GO:2000050)2.51103135
96inner ear receptor stereocilium organization (GO:0060122)2.49177099
97cilium assembly (GO:0042384)2.48891631
98pyrimidine nucleobase catabolic process (GO:0006208)2.47456359
99cranial nerve development (GO:0021545)2.46531979
100nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.43379076

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.10306038
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.70664590
3FUS_26573619_Chip-Seq_HEK293_Human2.69431839
4RBPJ_22232070_ChIP-Seq_NCS_Mouse2.62303369
5VDR_22108803_ChIP-Seq_LS180_Human2.61313235
6CBX2_27304074_Chip-Seq_ESCs_Mouse2.58510574
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.56477958
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.50228223
9GBX2_23144817_ChIP-Seq_PC3_Human2.45555925
10EWS_26573619_Chip-Seq_HEK293_Human2.37136973
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.34761482
12TAF15_26573619_Chip-Seq_HEK293_Human2.30036116
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29151949
14POU3F2_20337985_ChIP-ChIP_501MEL_Human2.27951673
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.26646488
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.21004354
17CTBP2_25329375_ChIP-Seq_LNCAP_Human2.20675817
18P300_19829295_ChIP-Seq_ESCs_Human2.20047899
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.19092282
20TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.11010856
21ZNF274_21170338_ChIP-Seq_K562_Hela2.09692646
22CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.00324618
23BMI1_23680149_ChIP-Seq_NPCS_Mouse1.95823068
24POU5F1_16153702_ChIP-ChIP_HESCs_Human1.94459339
25EZH2_27304074_Chip-Seq_ESCs_Mouse1.93499352
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.90687990
27HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.85624589
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.79292506
29KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.76017455
30RNF2_27304074_Chip-Seq_NSC_Mouse1.68620972
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67310143
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.65383375
33TP63_19390658_ChIP-ChIP_HaCaT_Human1.62278322
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.61919160
35IGF1R_20145208_ChIP-Seq_DFB_Human1.59668452
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.59515264
37TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58972396
38POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.58972396
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.58502548
40ELK1_19687146_ChIP-ChIP_HELA_Human1.57826637
41ER_23166858_ChIP-Seq_MCF-7_Human1.56919246
42MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.56438076
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56193710
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.55687547
45SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.54319122
46JARID2_20064375_ChIP-Seq_MESCs_Mouse1.53475654
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.51684982
48UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.45359873
49AR_25329375_ChIP-Seq_VCAP_Human1.45015792
50SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.43198890
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41818581
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41001743
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.36969891
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36953174
55SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.36775398
56PCGF2_27294783_Chip-Seq_ESCs_Mouse1.35830496
57SMAD4_21799915_ChIP-Seq_A2780_Human1.35479257
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34229884
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.33144784
60KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.32560516
61SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.30484397
62MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.28960196
63CBP_20019798_ChIP-Seq_JUKART_Human1.27206070
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27206070
65BCAT_22108803_ChIP-Seq_LS180_Human1.26700828
66NANOG_18555785_Chip-Seq_ESCs_Mouse1.26466137
67PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.24765891
68PCGF2_27294783_Chip-Seq_NPCs_Mouse1.24221400
69SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.24007463
70EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.22320850
71SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21519125
72CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.20283639
73TCF4_22108803_ChIP-Seq_LS180_Human1.19576742
74MYC_18940864_ChIP-ChIP_HL60_Human1.19010243
75RNF2_27304074_Chip-Seq_ESCs_Mouse1.18697878
76AR_21572438_ChIP-Seq_LNCaP_Human1.17063622
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16825553
78SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.16310019
79* SOX2_19829295_ChIP-Seq_ESCs_Human1.15232759
80* NANOG_19829295_ChIP-Seq_ESCs_Human1.15232759
81NFE2_27457419_Chip-Seq_LIVER_Mouse1.15030637
82SOX2_16153702_ChIP-ChIP_HESCs_Human1.13995789
83REST_21632747_ChIP-Seq_MESCs_Mouse1.12586572
84JARID2_20075857_ChIP-Seq_MESCs_Mouse1.11816424
85CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11483307
86EZH2_27294783_Chip-Seq_NPCs_Mouse1.10692556
87P53_22387025_ChIP-Seq_ESCs_Mouse1.10683893
88RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.08887332
89RNF2_18974828_ChIP-Seq_MESCs_Mouse1.08708606
90EZH2_18974828_ChIP-Seq_MESCs_Mouse1.08708606
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07412116
92E2F1_18555785_Chip-Seq_ESCs_Mouse1.02674831
93NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01632796
94RUNX2_22187159_ChIP-Seq_PCA_Human1.00536061
95LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00288491
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98479552
97FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.98127240
98CMYC_18555785_Chip-Seq_ESCs_Mouse0.95143846
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94144890
100VDR_23849224_ChIP-Seq_CD4+_Human0.93339155

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color5.75088772
2MP0000566_synostosis4.27897049
3MP0009379_abnormal_foot_pigmentation3.94860795
4MP0002938_white_spotting3.04209560
5MP0010030_abnormal_orbit_morphology3.02903569
6MP0000372_irregular_coat_pigmentation2.76223828
7MP0005171_absent_coat_pigmentation2.68146968
8MP0003880_abnormal_central_pattern2.59196691
9MP0006292_abnormal_olfactory_placode2.31262423
10MP0002102_abnormal_ear_morphology2.30862664
11MP0000569_abnormal_digit_pigmentation2.29637747
12MP0002277_abnormal_respiratory_mucosa2.15852471
13MP0002282_abnormal_trachea_morphology1.94714642
14MP0001529_abnormal_vocalization1.91670631
15MP0006072_abnormal_retinal_apoptosis1.90121921
16MP0002928_abnormal_bile_duct1.89814721
17MP0000778_abnormal_nervous_system1.88792239
18MP0000631_abnormal_neuroendocrine_gland1.87520343
19MP0004142_abnormal_muscle_tone1.87424453
20MP0004133_heterotaxia1.84225492
21MP0005084_abnormal_gallbladder_morpholo1.83890486
22MP0002638_abnormal_pupillary_reflex1.76631868
23MP0002822_catalepsy1.74853342
24MP0005187_abnormal_penis_morphology1.73371327
25MP0002234_abnormal_pharynx_morphology1.69327812
26MP0003011_delayed_dark_adaptation1.66643741
27MP0003890_abnormal_embryonic-extraembry1.64342448
28MP0001346_abnormal_lacrimal_gland1.54595680
29MP0001293_anophthalmia1.51887869
30MP0005408_hypopigmentation1.48385530
31MP0003938_abnormal_ear_development1.46505231
32MP0005253_abnormal_eye_physiology1.43416057
33MP0000026_abnormal_inner_ear1.41129149
34MP0004742_abnormal_vestibular_system1.40708009
35MP0001485_abnormal_pinna_reflex1.39698706
36MP0002653_abnormal_ependyma_morphology1.38844219
37MP0006276_abnormal_autonomic_nervous1.37093029
38MP0001324_abnormal_eye_pigmentation1.36287191
39MP0000537_abnormal_urethra_morphology1.35417289
40MP0004885_abnormal_endolymph1.34753730
41MP0003937_abnormal_limbs/digits/tail_de1.31694659
42MP0002751_abnormal_autonomic_nervous1.30485824
43MP0005551_abnormal_eye_electrophysiolog1.27949272
44MP0009745_abnormal_behavioral_response1.27419371
45MP0001286_abnormal_eye_development1.26381852
46MP0005174_abnormal_tail_pigmentation1.26295893
47MP0002095_abnormal_skin_pigmentation1.19478438
48MP0003315_abnormal_perineum_morphology1.19050019
49MP0001984_abnormal_olfaction1.13752622
50MP0003283_abnormal_digestive_organ1.13684919
51MP0002272_abnormal_nervous_system1.10533351
52MP0005646_abnormal_pituitary_gland1.09013535
53MP0008995_early_reproductive_senescence1.07936073
54MP0001486_abnormal_startle_reflex1.07465051
55MP0005367_renal/urinary_system_phenotyp1.05513964
56MP0000516_abnormal_urinary_system1.05513964
57MP0000049_abnormal_middle_ear1.05433376
58MP0002697_abnormal_eye_size1.04059956
59MP0004145_abnormal_muscle_electrophysio1.03028525
60MP0002735_abnormal_chemical_nociception1.02162260
61MP0005391_vision/eye_phenotype1.01139810
62MP0002233_abnormal_nose_morphology1.00255425
63MP0002736_abnormal_nociception_after0.99084091
64MP0008789_abnormal_olfactory_epithelium0.98340170
65MP0002572_abnormal_emotion/affect_behav0.97536578
66MP0002064_seizures0.96944630
67MP0005423_abnormal_somatic_nervous0.94504566
68MP0000647_abnormal_sebaceous_gland0.93850762
69MP0005377_hearing/vestibular/ear_phenot0.93471081
70MP0003878_abnormal_ear_physiology0.93471081
71MP0003119_abnormal_digestive_system0.93130754
72MP0005248_abnormal_Harderian_gland0.93091088
73MP0002752_abnormal_somatic_nervous0.92813793
74MP0001905_abnormal_dopamine_level0.92460838
75MP0003718_maternal_effect0.91507768
76MP0005195_abnormal_posterior_eye0.91463383
77MP0002734_abnormal_mechanical_nocicepti0.91363512
78MP0002067_abnormal_sensory_capabilities0.88993457
79MP0002837_dystrophic_cardiac_calcinosis0.87222669
80MP0000955_abnormal_spinal_cord0.86547236
81MP0003755_abnormal_palate_morphology0.86177783
82MP0005075_abnormal_melanosome_morpholog0.83855531
83MP0001963_abnormal_hearing_physiology0.83014002
84MP0008877_abnormal_DNA_methylation0.81945003
85MP0003122_maternal_imprinting0.81417860
86MP0001440_abnormal_grooming_behavior0.77536808
87MP0002557_abnormal_social/conspecific_i0.77468612
88MP0001299_abnormal_eye_distance/0.77393601
89MP0005503_abnormal_tendon_morphology0.76507027
90MP0009250_abnormal_appendicular_skeleto0.75102207
91MP0003806_abnormal_nucleotide_metabolis0.74684084
92MP0000534_abnormal_ureter_morphology0.74607103
93MP0008961_abnormal_basal_metabolism0.73569976
94MP0003195_calcinosis0.70848545
95MP0003861_abnormal_nervous_system0.70243849
96MP0000579_abnormal_nail_morphology0.69642078
97MP0003635_abnormal_synaptic_transmissio0.69337843
98MP0002184_abnormal_innervation0.69064537
99MP0005499_abnormal_olfactory_system0.68619369
100MP0005394_taste/olfaction_phenotype0.68619369

Predicted human phenotypes

RankGene SetZ-score
1Septo-optic dysplasia (HP:0100842)4.14687448
2True hermaphroditism (HP:0010459)3.84115318
3Increased hepatocellular lipid droplets (HP:0006565)3.76824587
4Acute necrotizing encephalopathy (HP:0006965)3.76371689
5Pancreatic cysts (HP:0001737)3.57037374
6Congenital, generalized hypertrichosis (HP:0004540)3.55774899
7Abnormal ciliary motility (HP:0012262)3.40997264
8Pancreatic fibrosis (HP:0100732)3.36878093
9Reticulocytopenia (HP:0001896)3.34381950
10Mitochondrial inheritance (HP:0001427)3.33962767
11Progressive macrocephaly (HP:0004481)3.26841660
12Lipid accumulation in hepatocytes (HP:0006561)3.23602199
13Abnormal mitochondria in muscle tissue (HP:0008316)3.19919188
14Abnormal respiratory motile cilium physiology (HP:0012261)3.15274149
15Macrocytic anemia (HP:0001972)3.13769174
16Dynein arm defect of respiratory motile cilia (HP:0012255)3.13656590
17Absent/shortened dynein arms (HP:0200106)3.13656590
18Nephronophthisis (HP:0000090)3.13168987
19Abnormal number of erythroid precursors (HP:0012131)3.12418101
20Focal motor seizures (HP:0011153)3.12192827
21Molar tooth sign on MRI (HP:0002419)3.10168159
22Abnormality of midbrain morphology (HP:0002418)3.10168159
23Split foot (HP:0001839)3.07579830
24Renal Fanconi syndrome (HP:0001994)3.00160208
25Abnormal respiratory motile cilium morphology (HP:0005938)2.99573400
26Abnormal respiratory epithelium morphology (HP:0012253)2.99573400
27Absent septum pellucidum (HP:0001331)2.99518611
28Acute encephalopathy (HP:0006846)2.97611683
29Esophageal atresia (HP:0002032)2.96250421
30Abnormality of cells of the erythroid lineage (HP:0012130)2.91563463
31Concave nail (HP:0001598)2.88309194
32Gastrointestinal atresia (HP:0002589)2.84393702
33Abnormality of the labia minora (HP:0012880)2.73534276
34Increased CSF lactate (HP:0002490)2.70609633
353-Methylglutaconic aciduria (HP:0003535)2.58578393
36Sclerocornea (HP:0000647)2.53386731
37Medial flaring of the eyebrow (HP:0010747)2.52685820
38Exertional dyspnea (HP:0002875)2.52310888
39Rhinitis (HP:0012384)2.51749663
40Partial duplication of thumb phalanx (HP:0009944)2.50277613
41Abnormality of the renal medulla (HP:0100957)2.49206635
42Partial duplication of the phalanx of hand (HP:0009999)2.49130183
43Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.47819282
44Abnormality of the septum pellucidum (HP:0007375)2.43784374
45Maternal diabetes (HP:0009800)2.43208119
46Hepatocellular necrosis (HP:0001404)2.42816134
47Bilateral microphthalmos (HP:0007633)2.36471657
48Optic disc pallor (HP:0000543)2.35069664
49Congenital stationary night blindness (HP:0007642)2.35066565
50Optic nerve hypoplasia (HP:0000609)2.32468222
51Oligodactyly (hands) (HP:0001180)2.32231885
52Cystic liver disease (HP:0006706)2.31907814
53Aplasia/Hypoplasia of the tongue (HP:0010295)2.30386637
54Abnormality of the parietal bone (HP:0002696)2.25529146
55Genital tract atresia (HP:0001827)2.19182359
56Male pseudohermaphroditism (HP:0000037)2.18759349
57Intestinal atresia (HP:0011100)2.17665047
58Hepatic necrosis (HP:0002605)2.16986575
59Anophthalmia (HP:0000528)2.16361744
60Abnormal number of incisors (HP:0011064)2.12190687
61Vaginal atresia (HP:0000148)2.12181506
62Limb dystonia (HP:0002451)2.12173397
63Gait imbalance (HP:0002141)2.08683296
64Pallor (HP:0000980)2.07812390
65Abnormality of the phalanges of the 2nd finger (HP:0009541)2.06232357
66Abnormality of renal resorption (HP:0011038)2.05360605
67Anencephaly (HP:0002323)2.04359331
68Triphalangeal thumb (HP:0001199)2.04038391
69Leukodystrophy (HP:0002415)2.01278787
70Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.00717941
71Large for gestational age (HP:0001520)1.99280895
72Stenosis of the external auditory canal (HP:0000402)1.99061026
73Abnormality of abdominal situs (HP:0011620)1.98194181
74Abdominal situs inversus (HP:0003363)1.98194181
75Congenital primary aphakia (HP:0007707)1.97696666
76Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.96784630
77Cerebral edema (HP:0002181)1.94093347
78Hypothermia (HP:0002045)1.92263997
79Rib fusion (HP:0000902)1.90664066
80Type II lissencephaly (HP:0007260)1.89917394
81Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.88961988
82Myokymia (HP:0002411)1.88162288
83Midline defect of the nose (HP:0004122)1.84212489
84Preaxial hand polydactyly (HP:0001177)1.83942838
85Median cleft lip (HP:0000161)1.83527965
86Hemiparesis (HP:0001269)1.81718289
87Furrowed tongue (HP:0000221)1.81462533
88Increased intramyocellular lipid droplets (HP:0012240)1.81413709
89Bile duct proliferation (HP:0001408)1.81381588
90Abnormal biliary tract physiology (HP:0012439)1.81381588
91Nephrogenic diabetes insipidus (HP:0009806)1.80687423
92Hemivertebrae (HP:0002937)1.79757475
93Postaxial hand polydactyly (HP:0001162)1.76507498
94Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.75167174
95Short 4th metacarpal (HP:0010044)1.75167174
96Congenital hepatic fibrosis (HP:0002612)1.74168279
97Hypoplastic labia majora (HP:0000059)1.74116073
98Bifid tongue (HP:0010297)1.71613741
99Supernumerary spleens (HP:0009799)1.70735457
100Colon cancer (HP:0003003)1.70261620

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK5.44930873
2MAPK153.73852091
3WEE13.05245305
4VRK22.74040628
5TNIK2.64288548
6EPHB22.46934626
7WNK32.42772173
8VRK12.42759367
9FGFR22.26139652
10PASK2.25068434
11TSSK62.12134237
12ZAK2.11936686
13BMPR1B2.10943716
14TLK11.93529062
15MARK11.92829532
16DYRK21.83605597
17TGFBR11.74055856
18INSRR1.73882006
19NUAK11.68164100
20CASK1.61688391
21MAPK131.58666915
22MAP3K121.55538456
23MAP4K21.42945923
24DYRK31.36052301
25MAP3K41.28143817
26TAOK31.27610940
27PLK31.25200894
28EPHA31.20770023
29GRK11.19371007
30ADRBK21.18401366
31NTRK21.15098076
32MKNK11.13783827
33NME11.13276526
34FRK1.09391111
35STK241.08184389
36PAK31.07601060
37ERBB31.04034493
38MINK11.02043021
39STK38L1.01897990
40TRIM281.00851104
41CDK80.99778869
42WNK40.98939869
43EPHA40.92794473
44PRKCG0.92132488
45BRSK20.90877225
46PINK10.90740961
47MKNK20.90559352
48STK160.86714140
49CDK30.80882651
50STK390.79673972
51NTRK30.76931053
52CDC70.76125169
53FGFR10.75628140
54SRPK10.75377315
55GRK70.73966247
56TAF10.73578582
57ADRBK10.72855386
58ACVR1B0.68776954
59CCNB10.68444340
60OXSR10.63782856
61PRKCE0.63735537
62MUSK0.62118785
63PLK20.61614690
64EIF2AK30.59623559
65MAP2K40.59132192
66PKN10.58304869
67CSNK1G20.57531740
68NEK20.54167822
69UHMK10.50634863
70OBSCN0.50280356
71MST40.47503374
72PTK2B0.47393638
73PRKACA0.46075932
74NLK0.45715016
75STK30.44717478
76FLT30.44665296
77PRKG10.44223114
78PRKACB0.40913865
79CHEK20.40735712
80MAPKAPK50.39400646
81CSNK2A20.37530111
82CAMK2A0.37318530
83PLK40.37148464
84BUB10.36921213
85DYRK1A0.36880781
86IRAK20.35796806
87MAP2K70.35448295
88KIT0.34686557
89CSNK2A10.34370309
90KSR10.34082946
91BMPR20.32058238
92CHUK0.31715258
93CSNK1G10.31015634
94TIE10.30946224
95IRAK10.29903888
96MARK30.29114639
97ERBB20.27801857
98CAMK1G0.27184650
99RPS6KA50.27138545
100PLK10.27103778

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.02745976
2Oxidative phosphorylation_Homo sapiens_hsa001904.93778847
3Parkinsons disease_Homo sapiens_hsa050124.21398614
4Protein export_Homo sapiens_hsa030603.73156236
5Huntingtons disease_Homo sapiens_hsa050163.03355708
6Alzheimers disease_Homo sapiens_hsa050102.89286535
7Cardiac muscle contraction_Homo sapiens_hsa042602.70318828
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.52313545
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.42080559
10Proteasome_Homo sapiens_hsa030502.23947729
11Maturity onset diabetes of the young_Homo sapiens_hsa049502.13837003
12RNA polymerase_Homo sapiens_hsa030202.08107740
13Homologous recombination_Homo sapiens_hsa034401.76864271
14Asthma_Homo sapiens_hsa053101.75391080
15Nicotine addiction_Homo sapiens_hsa050331.72768898
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.50142397
17Basal cell carcinoma_Homo sapiens_hsa052171.48632209
18Basal transcription factors_Homo sapiens_hsa030221.48621816
19Fanconi anemia pathway_Homo sapiens_hsa034601.34081345
20Phototransduction_Homo sapiens_hsa047441.33016676
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29652178
22Butanoate metabolism_Homo sapiens_hsa006501.28766469
23Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25423471
24Hedgehog signaling pathway_Homo sapiens_hsa043401.23646821
25Nitrogen metabolism_Homo sapiens_hsa009101.21180136
26RNA degradation_Homo sapiens_hsa030181.16560408
27Mismatch repair_Homo sapiens_hsa034301.08719664
28Nucleotide excision repair_Homo sapiens_hsa034201.04147225
29Folate biosynthesis_Homo sapiens_hsa007901.02491164
30Spliceosome_Homo sapiens_hsa030401.01292318
31Autoimmune thyroid disease_Homo sapiens_hsa053200.99986229
32Collecting duct acid secretion_Homo sapiens_hsa049660.99204488
33Propanoate metabolism_Homo sapiens_hsa006400.97738565
34Taste transduction_Homo sapiens_hsa047420.96780975
35Allograft rejection_Homo sapiens_hsa053300.95822137
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.95090741
37Type I diabetes mellitus_Homo sapiens_hsa049400.93479799
38Intestinal immune network for IgA production_Homo sapiens_hsa046720.92355821
39Graft-versus-host disease_Homo sapiens_hsa053320.90968080
40Rheumatoid arthritis_Homo sapiens_hsa053230.86780346
41Linoleic acid metabolism_Homo sapiens_hsa005910.84559260
42Steroid biosynthesis_Homo sapiens_hsa001000.84060056
43Chemical carcinogenesis_Homo sapiens_hsa052040.83425184
44GABAergic synapse_Homo sapiens_hsa047270.82028775
45Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.79843668
46Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.78312169
47Tryptophan metabolism_Homo sapiens_hsa003800.77822180
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.77027910
49Olfactory transduction_Homo sapiens_hsa047400.76059321
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73464666
51TGF-beta signaling pathway_Homo sapiens_hsa043500.72424776
52Primary bile acid biosynthesis_Homo sapiens_hsa001200.72373905
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69497000
54Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.69112924
55Non-homologous end-joining_Homo sapiens_hsa034500.68071081
56Glutamatergic synapse_Homo sapiens_hsa047240.67593757
57Purine metabolism_Homo sapiens_hsa002300.67036107
58Morphine addiction_Homo sapiens_hsa050320.62062421
59Regulation of autophagy_Homo sapiens_hsa041400.62028442
60Cocaine addiction_Homo sapiens_hsa050300.59760905
61Circadian entrainment_Homo sapiens_hsa047130.59136817
62Caffeine metabolism_Homo sapiens_hsa002320.57498722
63Serotonergic synapse_Homo sapiens_hsa047260.57052562
64alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55401620
65Systemic lupus erythematosus_Homo sapiens_hsa053220.54995184
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52237333
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.50923159
68Metabolic pathways_Homo sapiens_hsa011000.50815290
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50596551
70Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.50483729
71Pyrimidine metabolism_Homo sapiens_hsa002400.48640862
72Antigen processing and presentation_Homo sapiens_hsa046120.48208980
73Wnt signaling pathway_Homo sapiens_hsa043100.42672537
74Tyrosine metabolism_Homo sapiens_hsa003500.41973616
75Glutathione metabolism_Homo sapiens_hsa004800.41139589
76Retinol metabolism_Homo sapiens_hsa008300.40458388
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39726532
78Axon guidance_Homo sapiens_hsa043600.39329345
79RNA transport_Homo sapiens_hsa030130.39167414
80Pyruvate metabolism_Homo sapiens_hsa006200.38309207
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.35159144
82Amphetamine addiction_Homo sapiens_hsa050310.34035587
83Vitamin digestion and absorption_Homo sapiens_hsa049770.32750515
84Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.32018889
85DNA replication_Homo sapiens_hsa030300.31980073
86Peroxisome_Homo sapiens_hsa041460.31862000
87Ether lipid metabolism_Homo sapiens_hsa005650.31724625
88Hippo signaling pathway_Homo sapiens_hsa043900.31310650
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29923727
90Cell cycle_Homo sapiens_hsa041100.29637689
91Dopaminergic synapse_Homo sapiens_hsa047280.28136280
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28072796
93Staphylococcus aureus infection_Homo sapiens_hsa051500.28048310
94Melanogenesis_Homo sapiens_hsa049160.27660412
95One carbon pool by folate_Homo sapiens_hsa006700.27456009
96Oocyte meiosis_Homo sapiens_hsa041140.27290606
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26746435
98Calcium signaling pathway_Homo sapiens_hsa040200.26583576
99Cholinergic synapse_Homo sapiens_hsa047250.26424985
100Circadian rhythm_Homo sapiens_hsa047100.26346812

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »