Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.93898524 |
2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.61463559 |
3 | negative regulation of cell killing (GO:0031342) | 4.61463559 |
4 | negative T cell selection (GO:0043383) | 4.50335609 |
5 | positive thymic T cell selection (GO:0045059) | 4.34857953 |
6 | negative thymic T cell selection (GO:0045060) | 4.34762841 |
7 | interferon-gamma production (GO:0032609) | 4.32540034 |
8 | microglial cell activation (GO:0001774) | 4.19898875 |
9 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.12088910 |
10 | positive T cell selection (GO:0043368) | 4.04528744 |
11 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.99488628 |
12 | T cell migration (GO:0072678) | 3.95109357 |
13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.93503291 |
14 | detection of molecule of bacterial origin (GO:0032490) | 3.83041619 |
15 | thymic T cell selection (GO:0045061) | 3.79359643 |
16 | positive regulation of granulocyte differentiation (GO:0030854) | 3.75611032 |
17 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.75213783 |
18 | T cell selection (GO:0045058) | 3.72831254 |
19 | cellular response to interleukin-15 (GO:0071350) | 3.67116935 |
20 | macrophage activation involved in immune response (GO:0002281) | 3.65945370 |
21 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.63662347 |
22 | leukocyte aggregation (GO:0070486) | 3.59776889 |
23 | tolerance induction (GO:0002507) | 3.57974521 |
24 | hepatocyte apoptotic process (GO:0097284) | 3.54357024 |
25 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.44723632 |
26 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.41822018 |
27 | mature B cell differentiation (GO:0002335) | 3.37714014 |
28 | negative regulation of B cell proliferation (GO:0030889) | 3.36486304 |
29 | regulation of gamma-delta T cell activation (GO:0046643) | 3.35942674 |
30 | regulation of T cell tolerance induction (GO:0002664) | 3.35609236 |
31 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.35034033 |
32 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.34791645 |
33 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.34523977 |
34 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.33323749 |
35 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.33323749 |
36 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.33212741 |
37 | NIK/NF-kappaB signaling (GO:0038061) | 3.31129314 |
38 | response to interleukin-15 (GO:0070672) | 3.30938274 |
39 | neutrophil mediated immunity (GO:0002446) | 3.29234408 |
40 | neutrophil activation (GO:0042119) | 3.26919353 |
41 | response to muramyl dipeptide (GO:0032495) | 3.25259431 |
42 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.24631257 |
43 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.23942450 |
44 | detection of other organism (GO:0098543) | 3.22885841 |
45 | detection of external biotic stimulus (GO:0098581) | 3.22240764 |
46 | neutrophil activation involved in immune response (GO:0002283) | 3.21013629 |
47 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.20033666 |
48 | response to host immune response (GO:0052572) | 3.20033666 |
49 | macrophage activation (GO:0042116) | 3.19269306 |
50 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.17042825 |
51 | myeloid dendritic cell activation (GO:0001773) | 3.16472704 |
52 | regulation of regulatory T cell differentiation (GO:0045589) | 3.14133010 |
53 | myeloid cell activation involved in immune response (GO:0002275) | 3.13955552 |
54 | myeloid leukocyte mediated immunity (GO:0002444) | 3.13407158 |
55 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.12842261 |
56 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.10982727 |
57 | activated T cell proliferation (GO:0050798) | 3.09817963 |
58 | negative regulation of adaptive immune response (GO:0002820) | 3.09288572 |
59 | cellular response to ethanol (GO:0071361) | 3.06031409 |
60 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.05859203 |
61 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.04327943 |
62 | mast cell activation (GO:0045576) | 3.00206224 |
63 | granulocyte activation (GO:0036230) | 3.00121720 |
64 | cellular extravasation (GO:0045123) | 2.99224937 |
65 | positive regulation of interleukin-2 production (GO:0032743) | 2.98989148 |
66 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.97629454 |
67 | T cell costimulation (GO:0031295) | 2.97298795 |
68 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.97203993 |
69 | B cell receptor signaling pathway (GO:0050853) | 2.97125449 |
70 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.95373679 |
71 | defense response to protozoan (GO:0042832) | 2.95036057 |
72 | myeloid dendritic cell differentiation (GO:0043011) | 2.94447286 |
73 | lymphocyte costimulation (GO:0031294) | 2.92736132 |
74 | positive regulation of isotype switching (GO:0045830) | 2.91198697 |
75 | regulation of B cell differentiation (GO:0045577) | 2.89130535 |
76 | dendritic cell chemotaxis (GO:0002407) | 2.88548955 |
77 | detection of bacterium (GO:0016045) | 2.88214096 |
78 | regulation of RIG-I signaling pathway (GO:0039535) | 2.87933338 |
79 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.87808301 |
80 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.86748341 |
81 | detection of biotic stimulus (GO:0009595) | 2.86553719 |
82 | response to peptidoglycan (GO:0032494) | 2.85821119 |
83 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.85320026 |
84 | T cell receptor signaling pathway (GO:0050852) | 2.84868744 |
85 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.84536137 |
86 | response to host (GO:0075136) | 2.84536137 |
87 | response to host defenses (GO:0052200) | 2.84536137 |
88 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.83452134 |
89 | histone H3-K4 trimethylation (GO:0080182) | 2.81721813 |
90 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.81311411 |
91 | negative regulation of T cell mediated immunity (GO:0002710) | 2.80003474 |
92 | mast cell degranulation (GO:0043303) | 2.80003365 |
93 | mast cell activation involved in immune response (GO:0002279) | 2.80003365 |
94 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.79106300 |
95 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.79106300 |
96 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.78825520 |
97 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.78605146 |
98 | positive regulation of antigen processing and presentation (GO:0002579) | 2.78334742 |
99 | dendritic cell migration (GO:0036336) | 2.78132333 |
100 | positive regulation of mast cell activation (GO:0033005) | 2.77369066 |
101 | positive regulation of DNA recombination (GO:0045911) | 2.76756829 |
102 | regulation of mast cell activation (GO:0033003) | 2.76249356 |
103 | regulation of tolerance induction (GO:0002643) | 2.75573139 |
104 | positive regulation of defense response to virus by host (GO:0002230) | 2.73827761 |
105 | regulation of granulocyte differentiation (GO:0030852) | 2.69811450 |
106 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.68829056 |
107 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.68398117 |
108 | T-helper cell differentiation (GO:0042093) | 2.68398117 |
109 | T cell homeostasis (GO:0043029) | 2.65891679 |
110 | alpha-beta T cell activation (GO:0046631) | 2.63500065 |
111 | positive regulation of humoral immune response (GO:0002922) | 2.63088968 |
112 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.62269052 |
113 | T cell proliferation (GO:0042098) | 2.61442154 |
114 | regulation of antigen processing and presentation (GO:0002577) | 2.61266333 |
115 | respiratory burst (GO:0045730) | 2.60090429 |
116 | positive regulation of B cell differentiation (GO:0045579) | 2.59041909 |
117 | positive regulation of B cell proliferation (GO:0030890) | 2.58863788 |
118 | immunoglobulin mediated immune response (GO:0016064) | 2.57975022 |
119 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.57266712 |
120 | natural killer cell activation (GO:0030101) | 2.55792703 |
121 | B cell homeostasis (GO:0001782) | 2.55361963 |
122 | monocyte chemotaxis (GO:0002548) | 2.55270304 |
123 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.54437321 |
124 | response to type I interferon (GO:0034340) | 2.53176326 |
125 | regulation of hypersensitivity (GO:0002883) | 2.52743148 |
126 | cellular defense response (GO:0006968) | 2.52664678 |
127 | leukocyte cell-cell adhesion (GO:0007159) | 2.52507579 |
128 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.51695700 |
129 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.51695700 |
130 | modulation by symbiont of host immune response (GO:0052553) | 2.51695700 |
131 | positive regulation by symbiont of host defense response (GO:0052509) | 2.51695700 |
132 | modulation by symbiont of host defense response (GO:0052031) | 2.51695700 |
133 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.51695700 |
134 | alpha-beta T cell differentiation (GO:0046632) | 2.51210754 |
135 | type I interferon signaling pathway (GO:0060337) | 2.50543272 |
136 | cellular response to type I interferon (GO:0071357) | 2.50543272 |
137 | negative regulation of interleukin-12 production (GO:0032695) | 2.49147839 |
138 | positive regulation of B cell activation (GO:0050871) | 2.46656657 |
139 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.46146700 |
140 | positive regulation of B cell mediated immunity (GO:0002714) | 2.46146700 |
141 | lymphocyte homeostasis (GO:0002260) | 2.45493750 |
142 | regulation of B cell proliferation (GO:0030888) | 2.44345842 |
143 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.43159799 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.86918119 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.34634388 |
3 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.10997423 |
4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.67228609 |
5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.60182755 |
6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.50052248 |
7 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.45892937 |
8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.35674475 |
9 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.95330354 |
10 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.93624771 |
11 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.89107154 |
12 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.84648527 |
13 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.81397250 |
14 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.45768167 |
15 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.42805057 |
16 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.31928172 |
17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.27130616 |
18 | MYB_26560356_Chip-Seq_TH2_Human | 2.21533957 |
19 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.19055460 |
20 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.05592181 |
21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.98596062 |
22 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.98282973 |
23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.93327303 |
24 | * FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.89190251 |
25 | * MYB_26560356_Chip-Seq_TH1_Human | 1.88106189 |
26 | * PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.87751204 |
27 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.77596598 |
28 | MAF_26560356_Chip-Seq_TH1_Human | 1.70309142 |
29 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.67125763 |
30 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.66972135 |
31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.59767084 |
32 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.54780756 |
33 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.54227074 |
34 | * SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.53393469 |
35 | GATA1_22025678_ChIP-Seq_K562_Human | 1.47801639 |
36 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.47511794 |
37 | * NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.47349754 |
38 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47259598 |
39 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.46359038 |
40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45551655 |
41 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.45025003 |
42 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.44307476 |
43 | * EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.40497927 |
44 | * PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39306890 |
45 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38683564 |
46 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.36992203 |
47 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.36272588 |
48 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.35074073 |
49 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.34655577 |
50 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.34059179 |
51 | SPI1_23127762_ChIP-Seq_K562_Human | 1.32115323 |
52 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.30069611 |
53 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.29212998 |
54 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.28621286 |
55 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.28183846 |
56 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.25668432 |
57 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.23623496 |
58 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.22501030 |
59 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.21822893 |
60 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.21651841 |
61 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.20641332 |
62 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.20409894 |
63 | * NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.19307022 |
64 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.18504736 |
65 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.17152823 |
66 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.16647322 |
67 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.14640290 |
68 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.13970897 |
69 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.13941144 |
70 | * STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.13076516 |
71 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.12343991 |
72 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.12229213 |
73 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.10923899 |
74 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10726486 |
75 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.10696292 |
76 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.10229120 |
77 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.08644049 |
78 | * EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.07736487 |
79 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.06603934 |
80 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.06408847 |
81 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.06075188 |
82 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.05295013 |
83 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.05056580 |
84 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.04658842 |
85 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04530484 |
86 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.04324214 |
87 | * OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.02621028 |
88 | * P300_18555785_Chip-Seq_ESCs_Mouse | 1.01926405 |
89 | * RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.01323421 |
90 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.00531465 |
91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99783840 |
92 | * RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.99579787 |
93 | * GATA3_26560356_Chip-Seq_TH2_Human | 0.99460929 |
94 | MAF_26560356_Chip-Seq_TH2_Human | 0.99232376 |
95 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.98025845 |
96 | * ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.97606579 |
97 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.97130534 |
98 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.96620981 |
99 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.96200597 |
100 | * PU1_27457419_Chip-Seq_LIVER_Mouse | 0.96155000 |
101 | * STAT3_23295773_ChIP-Seq_U87_Human | 0.95226515 |
102 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95125938 |
103 | * SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.94697455 |
104 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.94471327 |
105 | * TAF15_26573619_Chip-Seq_HEK293_Human | 0.93351956 |
106 | * ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.92568803 |
107 | VDR_22108803_ChIP-Seq_LS180_Human | 0.92463690 |
108 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90801667 |
109 | GATA3_26560356_Chip-Seq_TH1_Human | 0.90627382 |
110 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.90377620 |
111 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.90283522 |
112 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.89792142 |
113 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.89792142 |
114 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.89668520 |
115 | * KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.89545216 |
116 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.88755526 |
117 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88560191 |
118 | TP53_16413492_ChIP-PET_HCT116_Human | 0.88529410 |
119 | * CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.87191909 |
120 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.86925340 |
121 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86905562 |
122 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.86639815 |
123 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.86605657 |
124 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.86240525 |
125 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.86078185 |
126 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85591417 |
127 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.85094503 |
128 | * POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.84709844 |
129 | * TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84709844 |
130 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.84261034 |
131 | * SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.84227209 |
132 | GATA2_19941826_ChIP-Seq_K562_Human | 0.83797425 |
133 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83488870 |
134 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.83001120 |
135 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.82933719 |
136 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.82009376 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.71769223 |
2 | MP0005671_abnormal_response_to | 3.68842188 |
3 | MP0003763_abnormal_thymus_physiology | 3.27609107 |
4 | MP0003303_peritoneal_inflammation | 3.05323429 |
5 | MP0003724_increased_susceptibility_to | 2.99182622 |
6 | MP0005000_abnormal_immune_tolerance | 2.88521907 |
7 | MP0001790_abnormal_immune_system | 2.84053047 |
8 | MP0005387_immune_system_phenotype | 2.84053047 |
9 | MP0001800_abnormal_humoral_immune | 2.82343549 |
10 | MP0000685_abnormal_immune_system | 2.75968867 |
11 | MP0005174_abnormal_tail_pigmentation | 2.59294166 |
12 | MP0002723_abnormal_immune_serum | 2.55041612 |
13 | MP0002452_abnormal_antigen_presenting | 2.54429474 |
14 | MP0003436_decreased_susceptibility_to | 2.54052758 |
15 | MP0002148_abnormal_hypersensitivity_rea | 2.53553364 |
16 | MP0009785_altered_susceptibility_to | 2.51755443 |
17 | MP0004381_abnormal_hair_follicle | 2.48560905 |
18 | MP0002420_abnormal_adaptive_immunity | 2.44997950 |
19 | MP0001819_abnormal_immune_cell | 2.43843604 |
20 | MP0003136_yellow_coat_color | 2.42568300 |
21 | MP0005409_darkened_coat_color | 2.39725682 |
22 | MP0005025_abnormal_response_to | 2.30356202 |
23 | MP0002419_abnormal_innate_immunity | 2.30154557 |
24 | MP0000015_abnormal_ear_pigmentation | 2.28532568 |
25 | MP0002166_altered_tumor_susceptibility | 2.05425521 |
26 | MP0002398_abnormal_bone_marrow | 2.02895130 |
27 | MP0002396_abnormal_hematopoietic_system | 2.00793925 |
28 | MP0000716_abnormal_immune_system | 1.98209152 |
29 | MP0005310_abnormal_salivary_gland | 1.97945436 |
30 | MP0002405_respiratory_system_inflammati | 1.97773764 |
31 | MP0009333_abnormal_splenocyte_physiolog | 1.95489884 |
32 | MP0001188_hyperpigmentation | 1.92783159 |
33 | MP0002006_tumorigenesis | 1.91375464 |
34 | MP0006082_CNS_inflammation | 1.82475412 |
35 | MP0006292_abnormal_olfactory_placode | 1.71000985 |
36 | MP0002009_preneoplasia | 1.66807340 |
37 | MP0003172_abnormal_lysosome_physiology | 1.65400284 |
38 | MP0002277_abnormal_respiratory_mucosa | 1.58455871 |
39 | MP0005464_abnormal_platelet_physiology | 1.58014616 |
40 | MP0008877_abnormal_DNA_methylation | 1.57514636 |
41 | MP0000689_abnormal_spleen_morphology | 1.55781595 |
42 | MP0001853_heart_inflammation | 1.55610071 |
43 | MP0002722_abnormal_immune_system | 1.53267866 |
44 | MP0004510_myositis | 1.50914869 |
45 | MP0002933_joint_inflammation | 1.48988422 |
46 | MP0010155_abnormal_intestine_physiology | 1.48515192 |
47 | MP0000703_abnormal_thymus_morphology | 1.48390884 |
48 | MP0002429_abnormal_blood_cell | 1.47331325 |
49 | MP0000465_gastrointestinal_hemorrhage | 1.46933301 |
50 | MP0004883_abnormal_blood_vessel | 1.46025136 |
51 | MP0001845_abnormal_inflammatory_respons | 1.44472174 |
52 | MP0001873_stomach_inflammation | 1.38763555 |
53 | MP0003183_abnormal_peptide_metabolism | 1.37395581 |
54 | MP0003866_abnormal_defecation | 1.36701025 |
55 | MP0002163_abnormal_gland_morphology | 1.36466944 |
56 | MP0002095_abnormal_skin_pigmentation | 1.35092111 |
57 | MP0001851_eye_inflammation | 1.30081979 |
58 | MP0001533_abnormal_skeleton_physiology | 1.29595718 |
59 | MP0003787_abnormal_imprinting | 1.29527534 |
60 | MP0000858_altered_metastatic_potential | 1.26627458 |
61 | MP0003448_altered_tumor_morphology | 1.19841134 |
62 | MP0003300_gastrointestinal_ulcer | 1.19741261 |
63 | MP0002998_abnormal_bone_remodeling | 1.19318269 |
64 | MP0000569_abnormal_digit_pigmentation | 1.18726971 |
65 | MP0003656_abnormal_erythrocyte_physiolo | 1.15063449 |
66 | MP0005075_abnormal_melanosome_morpholog | 1.11652095 |
67 | MP0005451_abnormal_body_composition | 1.09943229 |
68 | MP0003646_muscle_fatigue | 1.08466788 |
69 | MP0001986_abnormal_taste_sensitivity | 1.08064749 |
70 | MP0000490_abnormal_crypts_of | 1.08023446 |
71 | MP0004484_altered_response_of | 1.06119332 |
72 | MP0004947_skin_inflammation | 1.04494349 |
73 | MP0004130_abnormal_muscle_cell | 0.99757020 |
74 | MP0005257_abnormal_intraocular_pressure | 0.98957175 |
75 | MP0009764_decreased_sensitivity_to | 0.97275491 |
76 | MP0002102_abnormal_ear_morphology | 0.97077090 |
77 | MP0008057_abnormal_DNA_replication | 0.97063480 |
78 | MP0005379_endocrine/exocrine_gland_phen | 0.93675012 |
79 | MP0003828_pulmonary_edema | 0.92476267 |
80 | MP0008469_abnormal_protein_level | 0.90864953 |
81 | MP0002177_abnormal_outer_ear | 0.87182328 |
82 | MP0005164_abnormal_response_to | 0.87138108 |
83 | MP0004808_abnormal_hematopoietic_stem | 0.87135806 |
84 | MP0000372_irregular_coat_pigmentation | 0.86739685 |
85 | MP0003690_abnormal_glial_cell | 0.83587486 |
86 | MP0002138_abnormal_hepatobiliary_system | 0.83262533 |
87 | MP0003045_fibrosis | 0.82916113 |
88 | MP0002332_abnormal_exercise_endurance | 0.82587136 |
89 | MP0002693_abnormal_pancreas_physiology | 0.78699232 |
90 | MP0000427_abnormal_hair_cycle | 0.77908422 |
91 | MP0008260_abnormal_autophagy | 0.77835662 |
92 | MP0003195_calcinosis | 0.76230683 |
93 | MP0000604_amyloidosis | 0.75353465 |
94 | MP0000613_abnormal_salivary_gland | 0.75009277 |
95 | MP0009763_increased_sensitivity_to | 0.73991675 |
96 | MP0004742_abnormal_vestibular_system | 0.71852386 |
97 | MP0005397_hematopoietic_system_phenotyp | 0.71685561 |
98 | MP0001545_abnormal_hematopoietic_system | 0.71685561 |
99 | MP0005390_skeleton_phenotype | 0.69073092 |
100 | MP0009765_abnormal_xenobiotic_induced | 0.69026472 |
101 | MP0002019_abnormal_tumor_incidence | 0.68374308 |
102 | MP0003252_abnormal_bile_duct | 0.66943579 |
103 | MP0005058_abnormal_lysosome_morphology | 0.66250198 |
104 | MP0001346_abnormal_lacrimal_gland | 0.64910876 |
105 | MP0001663_abnormal_digestive_system | 0.64025049 |
106 | MP0003221_abnormal_cardiomyocyte_apopto | 0.64002106 |
107 | MP0003191_abnormal_cellular_cholesterol | 0.63179484 |
108 | MP0005167_abnormal_blood-brain_barrier | 0.59721168 |
109 | MP0000920_abnormal_myelination | 0.58792104 |
110 | MP0004142_abnormal_muscle_tone | 0.57255742 |
111 | MP0005645_abnormal_hypothalamus_physiol | 0.56976359 |
112 | MP0002928_abnormal_bile_duct | 0.56479643 |
113 | MP0003795_abnormal_bone_structure | 0.56020299 |
114 | MP0005376_homeostasis/metabolism_phenot | 0.54838989 |
115 | MP0000371_diluted_coat_color | 0.54683607 |
116 | MP0001186_pigmentation_phenotype | 0.54359052 |
117 | MP0002132_abnormal_respiratory_system | 0.54197071 |
118 | MP0001348_abnormal_lacrimal_gland | 0.53388367 |
119 | MP0002075_abnormal_coat/hair_pigmentati | 0.52646853 |
120 | MP0008058_abnormal_DNA_repair | 0.52486707 |
121 | MP0000249_abnormal_blood_vessel | 0.52401752 |
122 | MP0001919_abnormal_reproductive_system | 0.51764736 |
123 | MP0000681_abnormal_thyroid_gland | 0.50859797 |
124 | MP0009278_abnormal_bone_marrow | 0.50050690 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 4.30810076 |
2 | Eczematoid dermatitis (HP:0000976) | 4.07425583 |
3 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.91200845 |
4 | Retrobulbar optic neuritis (HP:0100654) | 3.90246317 |
5 | Optic neuritis (HP:0100653) | 3.90246317 |
6 | Agammaglobulinemia (HP:0004432) | 3.89570948 |
7 | Recurrent cutaneous fungal infections (HP:0011370) | 3.77019121 |
8 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.77019121 |
9 | Meningitis (HP:0001287) | 3.72951721 |
10 | Recurrent fungal infections (HP:0002841) | 3.72280181 |
11 | Myositis (HP:0100614) | 3.68582401 |
12 | Chronic obstructive pulmonary disease (HP:0006510) | 3.58870754 |
13 | Obstructive lung disease (HP:0006536) | 3.58870754 |
14 | Recurrent bacterial skin infections (HP:0005406) | 3.56678065 |
15 | Stomatitis (HP:0010280) | 3.54278230 |
16 | Panhypogammaglobulinemia (HP:0003139) | 3.51830757 |
17 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.46070992 |
18 | Abnormality of T cell number (HP:0011839) | 3.45653060 |
19 | T lymphocytopenia (HP:0005403) | 3.36716934 |
20 | Orchitis (HP:0100796) | 3.32301292 |
21 | Recurrent viral infections (HP:0004429) | 3.30145095 |
22 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.28361080 |
23 | Abnormality of the fingertips (HP:0001211) | 3.25082276 |
24 | Recurrent skin infections (HP:0001581) | 3.02159137 |
25 | Vasculitis (HP:0002633) | 2.97622331 |
26 | Mediastinal lymphadenopathy (HP:0100721) | 2.95051604 |
27 | Eosinophilia (HP:0001880) | 2.93671061 |
28 | Chronic otitis media (HP:0000389) | 2.90148053 |
29 | Pulmonary infiltrates (HP:0002113) | 2.87680290 |
30 | Abnormality of eosinophils (HP:0001879) | 2.81692819 |
31 | Abnormality of T cells (HP:0002843) | 2.80663489 |
32 | Severe combined immunodeficiency (HP:0004430) | 2.80035902 |
33 | Encephalitis (HP:0002383) | 2.80004615 |
34 | Thyroiditis (HP:0100646) | 2.75390552 |
35 | Leukocytosis (HP:0001974) | 2.74841807 |
36 | IgM deficiency (HP:0002850) | 2.71152609 |
37 | Gingival bleeding (HP:0000225) | 2.70955849 |
38 | Recurrent bronchitis (HP:0002837) | 2.69814672 |
39 | Hemoptysis (HP:0002105) | 2.66319398 |
40 | Stomach cancer (HP:0012126) | 2.66100935 |
41 | Gastrointestinal infarctions (HP:0005244) | 2.60184473 |
42 | Autoimmune thrombocytopenia (HP:0001973) | 2.54451670 |
43 | Inflammation of the large intestine (HP:0002037) | 2.53571924 |
44 | Abnormality of the prostate (HP:0008775) | 2.51761384 |
45 | Granulocytopenia (HP:0001913) | 2.45213518 |
46 | Cellulitis (HP:0100658) | 2.42201593 |
47 | Pulmonary embolism (HP:0002204) | 2.42172092 |
48 | Hypochromic microcytic anemia (HP:0004840) | 2.41428587 |
49 | Chronic diarrhea (HP:0002028) | 2.40937801 |
50 | Abnormality of T cell physiology (HP:0011840) | 2.38227809 |
51 | IgG deficiency (HP:0004315) | 2.37126097 |
52 | Recurrent sinusitis (HP:0011108) | 2.35444549 |
53 | Combined immunodeficiency (HP:0005387) | 2.34715275 |
54 | Keratoconjunctivitis sicca (HP:0001097) | 2.32370149 |
55 | Chromsome breakage (HP:0040012) | 2.31890346 |
56 | Prostate neoplasm (HP:0100787) | 2.31811913 |
57 | Lip pit (HP:0100267) | 2.30935652 |
58 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.29607586 |
59 | Hypoplasia of the thymus (HP:0000778) | 2.28722739 |
60 | Abnormality of macrophages (HP:0004311) | 2.27547389 |
61 | Genetic anticipation (HP:0003743) | 2.27371256 |
62 | Abnormality of B cell number (HP:0010975) | 2.26312861 |
63 | B lymphocytopenia (HP:0010976) | 2.26312861 |
64 | Type I transferrin isoform profile (HP:0003642) | 2.25620884 |
65 | Anorexia (HP:0002039) | 2.24885863 |
66 | Nasal polyposis (HP:0100582) | 2.24403202 |
67 | Reduced antithrombin III activity (HP:0001976) | 2.23396598 |
68 | Lymphopenia (HP:0001888) | 2.22848214 |
69 | Urticaria (HP:0001025) | 2.22654255 |
70 | Gastrointestinal inflammation (HP:0004386) | 2.21501578 |
71 | Colitis (HP:0002583) | 2.21498169 |
72 | Papilloma (HP:0012740) | 2.19846201 |
73 | Verrucae (HP:0200043) | 2.19846201 |
74 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.19285300 |
75 | Increased IgM level (HP:0003496) | 2.17426509 |
76 | Prolonged bleeding time (HP:0003010) | 2.17404536 |
77 | Abnormality of the pleura (HP:0002103) | 2.17239765 |
78 | Gingivitis (HP:0000230) | 2.17230585 |
79 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.17211676 |
80 | Recurrent pneumonia (HP:0006532) | 2.15597495 |
81 | Hypochromic anemia (HP:0001931) | 2.14629196 |
82 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.13377423 |
83 | Keratoconjunctivitis (HP:0001096) | 2.11660644 |
84 | Spontaneous hematomas (HP:0007420) | 2.11039923 |
85 | Thyroid-stimulating hormone excess (HP:0002925) | 2.10502272 |
86 | Autoimmune hemolytic anemia (HP:0001890) | 2.10128049 |
87 | Pustule (HP:0200039) | 2.10021439 |
88 | Arterial thrombosis (HP:0004420) | 2.09781678 |
89 | Hemiplegia (HP:0002301) | 2.06741795 |
90 | Viral hepatitis (HP:0006562) | 2.04149932 |
91 | Acute myeloid leukemia (HP:0004808) | 2.02755448 |
92 | Acute hepatic failure (HP:0006554) | 2.02565829 |
93 | Osteomyelitis (HP:0002754) | 2.00852269 |
94 | Slow saccadic eye movements (HP:0000514) | 2.00149428 |
95 | Ocular albinism (HP:0001107) | 1.99624788 |
96 | Cheilitis (HP:0100825) | 1.98358775 |
97 | Chronic sinusitis (HP:0011109) | 1.96893972 |
98 | Clubbing of toes (HP:0100760) | 1.96711288 |
99 | Hematochezia (HP:0002573) | 1.96595207 |
100 | Alveolar cell carcinoma (HP:0006519) | 1.95739800 |
101 | Recurrent lower respiratory tract infections (HP:0002783) | 1.95689048 |
102 | Episodic fever (HP:0001954) | 1.95053986 |
103 | Keratitis (HP:0000491) | 1.92783406 |
104 | Peritonitis (HP:0002586) | 1.92093597 |
105 | Epistaxis (HP:0000421) | 1.92045795 |
106 | Thrombocytosis (HP:0001894) | 1.90407009 |
107 | Periodontitis (HP:0000704) | 1.89432814 |
108 | Abnormality of the nasal mucosa (HP:0000433) | 1.89316354 |
109 | Chest pain (HP:0100749) | 1.89260925 |
110 | Spondylolisthesis (HP:0003302) | 1.86706129 |
111 | Hypoproteinemia (HP:0003075) | 1.86163927 |
112 | Sepsis (HP:0100806) | 1.85390297 |
113 | Bronchiectasis (HP:0002110) | 1.85137094 |
114 | Postural instability (HP:0002172) | 1.84869245 |
115 | Gaze-evoked nystagmus (HP:0000640) | 1.84050554 |
116 | Bronchitis (HP:0012387) | 1.83867443 |
117 | Microcytic anemia (HP:0001935) | 1.78983320 |
118 | Joint swelling (HP:0001386) | 1.78980220 |
119 | Papilledema (HP:0001085) | 1.78507626 |
120 | Increased IgE level (HP:0003212) | 1.78411539 |
121 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.76950321 |
122 | Pulmonary fibrosis (HP:0002206) | 1.76391187 |
123 | Absent frontal sinuses (HP:0002688) | 1.75974100 |
124 | Lymphoma (HP:0002665) | 1.73304352 |
125 | Gangrene (HP:0100758) | 1.73219420 |
126 | Hypergammaglobulinemia (HP:0010702) | 1.72656584 |
127 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.71348854 |
128 | Gastrointestinal stroma tumor (HP:0100723) | 1.69788098 |
129 | Attenuation of retinal blood vessels (HP:0007843) | 1.69129178 |
130 | IgA deficiency (HP:0002720) | 1.68994790 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TXK | 3.58047009 |
2 | TNIK | 3.39360661 |
3 | FRK | 3.36308941 |
4 | MAP4K1 | 3.21346510 |
5 | IRAK4 | 3.05524280 |
6 | BLK | 2.95979854 |
7 | CASK | 2.88071383 |
8 | NLK | 2.85943142 |
9 | MAP3K14 | 2.84648588 |
10 | MKNK2 | 2.46327250 |
11 | JAK3 | 2.37803844 |
12 | IRAK3 | 2.32884345 |
13 | IKBKE | 2.12902637 |
14 | TAOK3 | 2.01604615 |
15 | TEC | 2.00470782 |
16 | FES | 1.99531296 |
17 | ITK | 1.94322765 |
18 | IKBKB | 1.78978336 |
19 | CLK1 | 1.72769158 |
20 | TYK2 | 1.71361097 |
21 | CSK | 1.66692600 |
22 | ZAP70 | 1.59463491 |
23 | CAMKK2 | 1.57762419 |
24 | IRAK1 | 1.56142193 |
25 | MAP3K13 | 1.56089334 |
26 | STK10 | 1.55221529 |
27 | TGFBR2 | 1.49792307 |
28 | JAK1 | 1.45994538 |
29 | BTK | 1.45649278 |
30 | KIT | 1.43417877 |
31 | PRKD2 | 1.34503218 |
32 | NUAK1 | 1.34188223 |
33 | LCK | 1.31853059 |
34 | HCK | 1.25119150 |
35 | TLK1 | 1.23233292 |
36 | TBK1 | 1.21232565 |
37 | EIF2AK3 | 1.20920058 |
38 | SYK | 1.14233202 |
39 | RIPK4 | 1.11544269 |
40 | SGK2 | 1.08774640 |
41 | EIF2AK2 | 1.08250164 |
42 | PTK2B | 1.06154616 |
43 | MKNK1 | 1.05514819 |
44 | CHUK | 1.04872020 |
45 | EPHA3 | 1.04309468 |
46 | CDK3 | 1.02972428 |
47 | IRAK2 | 1.01655357 |
48 | LYN | 0.99107513 |
49 | BMPR2 | 0.98238836 |
50 | YES1 | 0.96068987 |
51 | HIPK2 | 0.90961392 |
52 | MAPK15 | 0.90220026 |
53 | MUSK | 0.89971092 |
54 | MAP3K2 | 0.89765614 |
55 | EPHB1 | 0.89667780 |
56 | WNK1 | 0.89660374 |
57 | GRK7 | 0.88771394 |
58 | PIM1 | 0.87919450 |
59 | PRKCQ | 0.79436372 |
60 | MAP3K6 | 0.79400758 |
61 | FGFR3 | 0.77153780 |
62 | MATK | 0.76568344 |
63 | CDK9 | 0.76137670 |
64 | ACVR1B | 0.75014408 |
65 | GRK5 | 0.74804769 |
66 | DMPK | 0.74365787 |
67 | PKN1 | 0.73540301 |
68 | MST4 | 0.73319727 |
69 | CSF1R | 0.73114284 |
70 | MAP4K2 | 0.71780783 |
71 | BMPR1B | 0.70969734 |
72 | PDK1 | 0.70691509 |
73 | TRPM7 | 0.69351743 |
74 | STK11 | 0.65948227 |
75 | MARK3 | 0.63929598 |
76 | ADRBK2 | 0.63912901 |
77 | SGK3 | 0.63712283 |
78 | SRPK1 | 0.63658881 |
79 | PAK3 | 0.60742339 |
80 | PINK1 | 0.60287275 |
81 | MAPK12 | 0.58643958 |
82 | CAMK4 | 0.58563847 |
83 | PRKAA2 | 0.58315664 |
84 | CAMKK1 | 0.57837842 |
85 | CDK8 | 0.56798589 |
86 | MAPK7 | 0.56280250 |
87 | GRK6 | 0.55538961 |
88 | MAP3K3 | 0.55205770 |
89 | ABL1 | 0.54998597 |
90 | STK4 | 0.54228833 |
91 | ADRBK1 | 0.54206438 |
92 | JAK2 | 0.54126978 |
93 | RPS6KA4 | 0.53832088 |
94 | MAP3K4 | 0.52933175 |
95 | MARK2 | 0.52767701 |
96 | RPS6KA5 | 0.52409857 |
97 | SGK223 | 0.51521602 |
98 | SGK494 | 0.51521602 |
99 | LATS1 | 0.50790047 |
100 | NEK9 | 0.50573854 |
101 | SIK2 | 0.50512940 |
102 | ERBB2 | 0.49831843 |
103 | INSRR | 0.49534242 |
104 | FGFR4 | 0.49238923 |
105 | MAP2K6 | 0.49036882 |
106 | STK3 | 0.48676902 |
107 | EGFR | 0.48010824 |
108 | MAP3K7 | 0.46946729 |
109 | FGR | 0.46861853 |
110 | CDK12 | 0.46700395 |
111 | FYN | 0.45607262 |
112 | CSNK1G1 | 0.45368453 |
113 | RAF1 | 0.45005501 |
114 | CDK19 | 0.44069443 |
115 | PLK4 | 0.43428139 |
116 | PIM2 | 0.42325137 |
117 | OXSR1 | 0.42237565 |
118 | MAPK13 | 0.41938479 |
119 | DYRK1A | 0.41264325 |
120 | SGK1 | 0.40853976 |
121 | BRD4 | 0.40602299 |
122 | TAOK1 | 0.40476496 |
123 | MAP3K5 | 0.37997140 |
124 | MAP2K3 | 0.37381997 |
125 | TNK2 | 0.36782058 |
126 | MAPK11 | 0.36426737 |
127 | PIK3CG | 0.36037547 |
128 | STK38 | 0.35296391 |
129 | VRK1 | 0.34437665 |
130 | MAPKAPK2 | 0.33958723 |
131 | MAP3K1 | 0.31944644 |
132 | GRK1 | 0.31376231 |
133 | PDGFRB | 0.30004586 |
134 | PIK3CA | 0.29901618 |
135 | STK24 | 0.29061964 |
136 | CDK4 | 0.28536596 |
137 | MELK | 0.27479876 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.05823770 |
2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.62902516 |
3 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.41584226 |
4 | Allograft rejection_Homo sapiens_hsa05330 | 2.38783585 |
5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.32738071 |
6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.32363757 |
7 | Leishmaniasis_Homo sapiens_hsa05140 | 2.03910502 |
8 | Measles_Homo sapiens_hsa05162 | 2.02401200 |
9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.99305879 |
10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.96240014 |
11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.96236570 |
12 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.91288194 |
13 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.80720149 |
14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.77448161 |
15 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.68992846 |
16 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.66582195 |
17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.60608641 |
18 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.59273155 |
19 | Other glycan degradation_Homo sapiens_hsa00511 | 1.55486512 |
20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.54647663 |
21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.50192796 |
22 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.43341534 |
23 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.41915666 |
24 | Asthma_Homo sapiens_hsa05310 | 1.36787136 |
25 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.35073109 |
26 | Malaria_Homo sapiens_hsa05144 | 1.34034277 |
27 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.25584927 |
28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.22433224 |
29 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.19673002 |
30 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.19443386 |
31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.19148793 |
32 | Influenza A_Homo sapiens_hsa05164 | 1.13948986 |
33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.12975788 |
34 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.11152377 |
35 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.10365318 |
36 | Hepatitis B_Homo sapiens_hsa05161 | 1.08630003 |
37 | Tuberculosis_Homo sapiens_hsa05152 | 1.07296633 |
38 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.06610134 |
39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.04830656 |
40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.03640800 |
41 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.02665978 |
42 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.01176698 |
43 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.01024400 |
44 | Pertussis_Homo sapiens_hsa05133 | 1.00605027 |
45 | Homologous recombination_Homo sapiens_hsa03440 | 0.99679552 |
46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.98397839 |
47 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.97419663 |
48 | Apoptosis_Homo sapiens_hsa04210 | 0.93207869 |
49 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.88771412 |
50 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.88409964 |
51 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.88288243 |
52 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.83136239 |
53 | Protein export_Homo sapiens_hsa03060 | 0.79922346 |
54 | Hepatitis C_Homo sapiens_hsa05160 | 0.79012014 |
55 | Phagosome_Homo sapiens_hsa04145 | 0.78293836 |
56 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.77732366 |
57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.77597536 |
58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.77507789 |
59 | Platelet activation_Homo sapiens_hsa04611 | 0.76373873 |
60 | Shigellosis_Homo sapiens_hsa05131 | 0.75912722 |
61 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.75317190 |
62 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.75118250 |
63 | Prostate cancer_Homo sapiens_hsa05215 | 0.74504983 |
64 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.73900639 |
65 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.73396314 |
66 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.71428104 |
67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70861427 |
68 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.67507989 |
69 | Salmonella infection_Homo sapiens_hsa05132 | 0.67496208 |
70 | HTLV-I infection_Homo sapiens_hsa05166 | 0.65929306 |
71 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.63068046 |
72 | Colorectal cancer_Homo sapiens_hsa05210 | 0.62670604 |
73 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.61603225 |
74 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.59444533 |
75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.58585699 |
76 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.56958158 |
77 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.56846429 |
78 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56436142 |
79 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.54677911 |
80 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.53612308 |
81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53575434 |
82 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.53436922 |
83 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.52624009 |
84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.52582286 |
85 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.52515867 |
86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52213194 |
87 | RNA degradation_Homo sapiens_hsa03018 | 0.52031340 |
88 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.52025047 |
89 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.50684786 |
90 | Phototransduction_Homo sapiens_hsa04744 | 0.50564412 |
91 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50419615 |
92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.49993770 |
93 | ABC transporters_Homo sapiens_hsa02010 | 0.49717922 |
94 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.49623366 |
95 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.49351046 |
96 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.48853675 |
97 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.48627119 |
98 | Morphine addiction_Homo sapiens_hsa05032 | 0.48306014 |
99 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47763720 |
100 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47311292 |
101 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.46872522 |
102 | Thyroid cancer_Homo sapiens_hsa05216 | 0.46452367 |
103 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.46425866 |
104 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.46295271 |
105 | Legionellosis_Homo sapiens_hsa05134 | 0.44397723 |
106 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.44005243 |
107 | Renin secretion_Homo sapiens_hsa04924 | 0.43710322 |
108 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.43257236 |
109 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.43180620 |
110 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.43139990 |
111 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.43124867 |
112 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.42689276 |
113 | Pathways in cancer_Homo sapiens_hsa05200 | 0.42551506 |
114 | Lysosome_Homo sapiens_hsa04142 | 0.41933247 |
115 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40281052 |
116 | Insulin resistance_Homo sapiens_hsa04931 | 0.39951211 |
117 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.38396041 |
118 | Circadian rhythm_Homo sapiens_hsa04710 | 0.38189302 |
119 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.38174970 |
120 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.38042799 |
121 | Endometrial cancer_Homo sapiens_hsa05213 | 0.36607429 |
122 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.36465570 |
123 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.35535866 |
124 | Taste transduction_Homo sapiens_hsa04742 | 0.34009985 |
125 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.33629513 |
126 | Long-term depression_Homo sapiens_hsa04730 | 0.30497912 |
127 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.29551296 |