ANKRD45

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1vocalization behavior (GO:0071625)6.09139522
2synaptic vesicle exocytosis (GO:0016079)5.62615564
3synaptic vesicle docking involved in exocytosis (GO:0016081)5.56146365
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.53746962
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.50626835
6axonemal dynein complex assembly (GO:0070286)5.47493228
7cilium movement (GO:0003341)5.44253210
8epithelial cilium movement (GO:0003351)5.43530026
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.41513801
10regulation of synaptic vesicle exocytosis (GO:2000300)5.34063620
11glutamate secretion (GO:0014047)5.33718820
12neuron cell-cell adhesion (GO:0007158)5.32869357
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.30442948
14neurotransmitter-gated ion channel clustering (GO:0072578)5.01171371
15protein localization to synapse (GO:0035418)4.98893515
16regulation of glutamate receptor signaling pathway (GO:1900449)4.95241221
17cilium or flagellum-dependent cell motility (GO:0001539)4.91857302
18regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.88839990
19regulation of synaptic vesicle transport (GO:1902803)4.75048340
20synaptic vesicle maturation (GO:0016188)4.71267650
21behavioral response to nicotine (GO:0035095)4.61855259
22locomotory exploration behavior (GO:0035641)4.55398083
23presynaptic membrane assembly (GO:0097105)4.51947660
24neurotransmitter secretion (GO:0007269)4.51126644
25positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.50006335
26ionotropic glutamate receptor signaling pathway (GO:0035235)4.49218603
27neuron-neuron synaptic transmission (GO:0007270)4.33442189
28positive regulation of synapse maturation (GO:0090129)4.29030582
29axoneme assembly (GO:0035082)4.26934227
30long-term synaptic potentiation (GO:0060291)4.26625708
31synaptic transmission, glutamatergic (GO:0035249)4.23242522
32neuronal action potential propagation (GO:0019227)4.21669687
33postsynaptic membrane organization (GO:0001941)4.20184100
34regulation of cilium movement (GO:0003352)4.17171265
35negative regulation of synaptic transmission, GABAergic (GO:0032229)4.13698955
36presynaptic membrane organization (GO:0097090)4.13635203
37membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.11633855
38glutamate receptor signaling pathway (GO:0007215)4.03693816
39regulation of neuronal synaptic plasticity (GO:0048168)3.97661229
40regulation of long-term neuronal synaptic plasticity (GO:0048169)3.95564267
41regulation of excitatory postsynaptic membrane potential (GO:0060079)3.86891288
42protein localization to cilium (GO:0061512)3.80788901
43exploration behavior (GO:0035640)3.79309598
44gamma-aminobutyric acid signaling pathway (GO:0007214)3.78693685
45intraciliary transport (GO:0042073)3.77644018
46platelet dense granule organization (GO:0060155)3.77447944
47response to histamine (GO:0034776)3.74774837
48gamma-aminobutyric acid transport (GO:0015812)3.73953921
49pyrimidine nucleobase catabolic process (GO:0006208)3.70924153
50nonmotile primary cilium assembly (GO:0035058)3.70862422
51regulation of postsynaptic membrane potential (GO:0060078)3.68261155
52regulation of synaptic plasticity (GO:0048167)3.65582471
53positive regulation of membrane potential (GO:0045838)3.65349554
54regulation of synaptic transmission, glutamatergic (GO:0051966)3.64409113
55cilium organization (GO:0044782)3.63420388
56regulation of synapse structural plasticity (GO:0051823)3.62476209
57positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.62102055
58regulation of glutamate secretion (GO:0014048)3.61697045
59neurotransmitter transport (GO:0006836)3.60829284
60striatum development (GO:0021756)3.60410097
61long-term memory (GO:0007616)3.59748827
62auditory behavior (GO:0031223)3.59582882
63regulation of neurotransmitter secretion (GO:0046928)3.58406737
64proline transport (GO:0015824)3.58262519
65L-fucose catabolic process (GO:0042355)3.58003227
66fucose catabolic process (GO:0019317)3.58003227
67L-fucose metabolic process (GO:0042354)3.58003227
68cerebellar granule cell differentiation (GO:0021707)3.55529442
69regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.54264804
70regulation of synapse maturation (GO:0090128)3.53585937
71cilium assembly (GO:0042384)3.53424082
72neuron recognition (GO:0008038)3.52913249
73synaptic vesicle endocytosis (GO:0048488)3.51287226
74cilium morphogenesis (GO:0060271)3.49819096
75regulation of female receptivity (GO:0045924)3.44411789
76behavioral response to cocaine (GO:0048148)3.42491935
77response to pheromone (GO:0019236)3.39394499
78transmission of nerve impulse (GO:0019226)3.39363492
79negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.36721266
80protein polyglutamylation (GO:0018095)3.35581883
81regulation of neurotransmitter transport (GO:0051588)3.34653348
82calcium ion-dependent exocytosis (GO:0017156)3.34229573
83negative regulation of neurotransmitter transport (GO:0051589)3.33813858
84regulation of neurotransmitter levels (GO:0001505)3.33469654
85regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.33397074
86negative regulation of dendrite morphogenesis (GO:0050774)3.31773646
87mechanosensory behavior (GO:0007638)3.31164840
88female mating behavior (GO:0060180)3.31004887
89startle response (GO:0001964)3.30329207
90neural tube formation (GO:0001841)3.29007506
91regulation of microtubule-based movement (GO:0060632)3.28784499
92positive regulation of synaptic transmission (GO:0050806)3.27483510
93learning (GO:0007612)3.24830665
94behavioral defense response (GO:0002209)3.24201408
95behavioral fear response (GO:0001662)3.24201408
96positive regulation of neurotransmitter secretion (GO:0001956)3.22724620
97membrane depolarization during action potential (GO:0086010)3.22071837
98protein-cofactor linkage (GO:0018065)3.21322025
99positive regulation of neurotransmitter transport (GO:0051590)3.20117217
100membrane depolarization (GO:0051899)3.20086068
101regulation of dendritic spine morphogenesis (GO:0061001)3.19932300
102response to auditory stimulus (GO:0010996)3.19295087
103layer formation in cerebral cortex (GO:0021819)3.19044725
104cerebellar Purkinje cell differentiation (GO:0021702)3.18174711
105motile cilium assembly (GO:0044458)3.16317565
106axonal fasciculation (GO:0007413)3.15311455
107positive regulation of synaptic transmission, GABAergic (GO:0032230)3.14054739
108G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.14022991
109nucleobase catabolic process (GO:0046113)3.13504725
110G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.13058125
111retinal cone cell development (GO:0046549)3.12848272
112substrate-independent telencephalic tangential migration (GO:0021826)3.10747928
113substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.10747928
114synapse assembly (GO:0007416)3.10552360
115DNA double-strand break processing (GO:0000729)3.10125759
116negative regulation of amino acid transport (GO:0051956)3.09155568
117synaptic transmission (GO:0007268)3.08788514
118negative regulation of neurotransmitter secretion (GO:0046929)3.07273534
119centriole replication (GO:0007099)3.06751918
120activation of protein kinase A activity (GO:0034199)3.05452448
121regulation of synaptic transmission (GO:0050804)3.05437592
122regulation of synaptic transmission, GABAergic (GO:0032228)3.02331721
123negative regulation of dendrite development (GO:2000171)3.02299082
124positive regulation of synapse assembly (GO:0051965)3.01747281
125fear response (GO:0042596)3.01577371
126detection of light stimulus involved in visual perception (GO:0050908)3.01325449
127detection of light stimulus involved in sensory perception (GO:0050962)3.01325449
128mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.00036506
129mitochondrial respiratory chain complex I assembly (GO:0032981)3.00036506
130NADH dehydrogenase complex assembly (GO:0010257)3.00036506
131protein complex biogenesis (GO:0070271)2.99540970
132piRNA metabolic process (GO:0034587)2.99232576
133ATP hydrolysis coupled proton transport (GO:0015991)2.97462151
134energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.97462151
135long term synaptic depression (GO:0060292)2.96482257
136dendritic spine morphogenesis (GO:0060997)2.95643779
137detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.86236054
138water-soluble vitamin biosynthetic process (GO:0042364)2.82702153
139multicellular organism reproduction (GO:0032504)2.81346726
140maturation of 5.8S rRNA (GO:0000460)2.80361609
141cornea development in camera-type eye (GO:0061303)2.78831114
142negative regulation of cytosolic calcium ion concentration (GO:0051481)2.78355185
143DNA deamination (GO:0045006)2.78263274
144negative regulation of telomere maintenance (GO:0032205)2.77535463
145mitochondrial respiratory chain complex assembly (GO:0033108)2.76972837
146sperm motility (GO:0030317)2.75762224
147left/right axis specification (GO:0070986)2.75657628
148photoreceptor cell maintenance (GO:0045494)2.75097183
149cellular component assembly involved in morphogenesis (GO:0010927)2.73352211
150spinal cord motor neuron differentiation (GO:0021522)2.72277309
151regulation of action potential (GO:0098900)2.71278889
152hindbrain development (GO:0030902)2.70042197
153behavioral response to ethanol (GO:0048149)2.69885996
154reciprocal DNA recombination (GO:0035825)2.68343888
155reciprocal meiotic recombination (GO:0007131)2.68343888
156regulation of collateral sprouting (GO:0048670)2.65754548
157DNA methylation involved in gamete generation (GO:0043046)2.60654924
158appendage development (GO:0048736)2.58545510
159limb development (GO:0060173)2.58545510
160mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.57425746
161male meiosis I (GO:0007141)2.56475071
162negative regulation of transcription regulatory region DNA binding (GO:2000678)2.56030401
163smoothened signaling pathway (GO:0007224)2.55476353
164positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.52857115
165rRNA catabolic process (GO:0016075)2.52426321
166neuronal action potential (GO:0019228)2.51049589
167preassembly of GPI anchor in ER membrane (GO:0016254)2.50156150
168C4-dicarboxylate transport (GO:0015740)2.49222402
169limb bud formation (GO:0060174)2.48304098
170microtubule bundle formation (GO:0001578)2.47413941
171retinal ganglion cell axon guidance (GO:0031290)2.45479938
172synapsis (GO:0007129)2.44816215
173photoreceptor cell development (GO:0042461)2.43548386
174regulation of meiosis I (GO:0060631)2.42845705
175reflex (GO:0060004)2.42508414
176regulation of rhodopsin mediated signaling pathway (GO:0022400)2.42311188
177dopamine transport (GO:0015872)2.41640501
178adaptation of signaling pathway (GO:0023058)2.41378616
179determination of left/right symmetry (GO:0007368)2.40130188
180mannosylation (GO:0097502)2.39649033
181regulation of telomere maintenance (GO:0032204)2.38491920
182nucleotide transmembrane transport (GO:1901679)2.37250278
183inner ear receptor stereocilium organization (GO:0060122)2.36382544
184male meiosis (GO:0007140)2.36077234
185cellular ketone body metabolic process (GO:0046950)2.35805034
186replication fork processing (GO:0031297)2.35023487
187positive regulation of sodium ion transmembrane transport (GO:1902307)2.33528957
188rhodopsin mediated signaling pathway (GO:0016056)2.31110510
189kidney morphogenesis (GO:0060993)2.31020697
190indolalkylamine metabolic process (GO:0006586)2.30334877

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.32659904
2GBX2_23144817_ChIP-Seq_PC3_Human4.02158301
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.99521886
4REST_21632747_ChIP-Seq_MESCs_Mouse2.77327352
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.68064655
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.63828686
7IGF1R_20145208_ChIP-Seq_DFB_Human2.53396041
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.48889089
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.40654457
10NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.33920764
11REST_18959480_ChIP-ChIP_MESCs_Mouse2.33421237
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.32052217
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.30652792
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.30410342
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.29835581
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.28941142
17RNF2_18974828_ChIP-Seq_MESCs_Mouse2.28941142
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.28505744
19TAF15_26573619_Chip-Seq_HEK293_Human2.26725758
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26372975
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21390470
22EWS_26573619_Chip-Seq_HEK293_Human2.19796793
23MTF2_20144788_ChIP-Seq_MESCs_Mouse2.16843289
24CTBP2_25329375_ChIP-Seq_LNCAP_Human2.15738542
25EED_16625203_ChIP-ChIP_MESCs_Mouse2.01616412
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.97578639
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97282469
28RNF2_27304074_Chip-Seq_ESCs_Mouse1.96740145
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.96284107
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.95632816
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.95504680
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.93368205
33SUZ12_27294783_Chip-Seq_ESCs_Mouse1.92795938
34DROSHA_22980978_ChIP-Seq_HELA_Human1.92759217
35EZH2_27294783_Chip-Seq_ESCs_Mouse1.86445349
36CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.84682320
37* SMAD4_21799915_ChIP-Seq_A2780_Human1.82255450
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.79266519
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.78256748
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77027970
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75709411
42IKZF1_21737484_ChIP-ChIP_HCT116_Human1.70792332
43P300_19829295_ChIP-Seq_ESCs_Human1.69270237
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.68158129
45AR_21572438_ChIP-Seq_LNCaP_Human1.67622702
46IRF1_19129219_ChIP-ChIP_H3396_Human1.67620546
47EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.61717426
48MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.59395201
49BMI1_23680149_ChIP-Seq_NPCS_Mouse1.58931868
50MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.54292694
51RNF2_27304074_Chip-Seq_NSC_Mouse1.50826193
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.50738873
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.48791592
54* TP53_22573176_ChIP-Seq_HFKS_Human1.47609900
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.46562228
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.44591207
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.43881457
58PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43153445
59GABP_17652178_ChIP-ChIP_JURKAT_Human1.42327898
60FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.41335121
61* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40391969
62SOX2_21211035_ChIP-Seq_LN229_Gbm1.39164458
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38614179
64FUS_26573619_Chip-Seq_HEK293_Human1.38333215
65MYC_18940864_ChIP-ChIP_HL60_Human1.37802579
66TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37546327
67PIAS1_25552417_ChIP-Seq_VCAP_Human1.37066360
68GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.36987420
69ERG_21242973_ChIP-ChIP_JURKAT_Human1.36902832
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.36175282
71STAT3_23295773_ChIP-Seq_U87_Human1.35625518
72* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.32521391
73KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.32089209
74PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.31354018
75VDR_22108803_ChIP-Seq_LS180_Human1.30242977
76AR_25329375_ChIP-Seq_VCAP_Human1.29779806
77TCF4_22108803_ChIP-Seq_LS180_Human1.28732400
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.28174801
79EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27498107
80KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25345330
81SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24660947
82NANOG_19829295_ChIP-Seq_ESCs_Human1.24650964
83SOX2_19829295_ChIP-Seq_ESCs_Human1.24650964
84OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24473254
85* TCF4_23295773_ChIP-Seq_U87_Human1.23821494
86EST1_17652178_ChIP-ChIP_JURKAT_Human1.23803197
87PCGF2_27294783_Chip-Seq_NPCs_Mouse1.23148750
88PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.22095412
89RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.19038361
90RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.17825511
91* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.17682278
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.17527437
93P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16172940
94ARNT_22903824_ChIP-Seq_MCF-7_Human1.13872892
95FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12656525
96FOXA1_25329375_ChIP-Seq_VCAP_Human1.12656525
97AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12364469
98* SMAD4_21741376_ChIP-Seq_EPCs_Human1.11771543
99MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11428767
100ETV2_25802403_ChIP-Seq_MESCs_Mouse1.11177245
101RING1B_27294783_Chip-Seq_ESCs_Mouse1.11061297
102* EZH2_27294783_Chip-Seq_NPCs_Mouse1.11046749
103AR_19668381_ChIP-Seq_PC3_Human1.10091559
104RUNX2_22187159_ChIP-Seq_PCA_Human1.09836469
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09311125
106ELK1_19687146_ChIP-ChIP_HELA_Human1.09192145
107ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08936186
108TAL1_26923725_Chip-Seq_HPCs_Mouse1.08267004
109* NFE2_27457419_Chip-Seq_LIVER_Mouse1.07465130
110GATA1_26923725_Chip-Seq_HPCs_Mouse1.06927799
111NR3C1_23031785_ChIP-Seq_PC12_Mouse1.06054705
112ZNF274_21170338_ChIP-Seq_K562_Hela1.05979829
113* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05643080
114* NCOR_22424771_ChIP-Seq_293T_Human1.04213005
115JUN_21703547_ChIP-Seq_K562_Human1.03956162
116* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.03622568
117ER_23166858_ChIP-Seq_MCF-7_Human1.03487367
118* NANOG_18555785_Chip-Seq_ESCs_Mouse1.03413960
119BCAT_22108803_ChIP-Seq_LS180_Human1.03112751
120CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02630615
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02581455
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02581455
123FLI1_27457419_Chip-Seq_LIVER_Mouse1.02276905
124SOX9_26525672_Chip-Seq_HEART_Mouse1.00978801
125YAP1_20516196_ChIP-Seq_MESCs_Mouse1.00954025
126FLI1_21867929_ChIP-Seq_TH2_Mouse1.00434029
127* P53_22387025_ChIP-Seq_ESCs_Mouse1.00412368
128AHR_22903824_ChIP-Seq_MCF-7_Human1.00168422
129KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.99470399
130PRDM14_20953172_ChIP-Seq_ESCs_Human0.99230534
131FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98929599
132AUTS2_25519132_ChIP-Seq_293T-REX_Human0.97645605
133SMAD3_21741376_ChIP-Seq_ESCs_Human0.97104247
134RING1B_27294783_Chip-Seq_NPCs_Mouse0.97100359
135* AR_20517297_ChIP-Seq_VCAP_Human0.96402783
136* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96380769
137TP53_16413492_ChIP-PET_HCT116_Human0.96342722
138TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96114687
139GATA3_21878914_ChIP-Seq_MCF-7_Human0.95994971
140ZNF217_24962896_ChIP-Seq_MCF-7_Human0.94841523
141NR3C1_21868756_ChIP-Seq_MCF10A_Human0.94778779
142* E2F1_18555785_Chip-Seq_ESCs_Mouse0.93041592
143CBP_20019798_ChIP-Seq_JUKART_Human0.89987319
144IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89987319
145RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89960794

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.74489770
2MP0003880_abnormal_central_pattern4.81782746
3MP0003635_abnormal_synaptic_transmissio4.07523131
4MP0009745_abnormal_behavioral_response3.53223345
5MP0002822_catalepsy3.52306618
6MP0009046_muscle_twitch3.38865157
7MP0004270_analgesia3.38037736
8MP0002063_abnormal_learning/memory/cond3.37726008
9MP0002064_seizures3.19311032
10MP0001968_abnormal_touch/_nociception3.11493836
11MP0002572_abnormal_emotion/affect_behav2.97682135
12MP0002102_abnormal_ear_morphology2.76306835
13MP0002736_abnormal_nociception_after2.64032884
14MP0002734_abnormal_mechanical_nocicepti2.57305298
15MP0002272_abnormal_nervous_system2.53379524
16MP0001486_abnormal_startle_reflex2.46206810
17MP0001188_hyperpigmentation2.38554195
18MP0001501_abnormal_sleep_pattern2.28053639
19MP0002735_abnormal_chemical_nociception2.25451490
20MP0005646_abnormal_pituitary_gland2.13073250
21MP0005423_abnormal_somatic_nervous2.10563232
22MP0001440_abnormal_grooming_behavior2.09595756
23MP0003136_yellow_coat_color2.07043307
24MP0002067_abnormal_sensory_capabilities1.99194906
25MP0002733_abnormal_thermal_nociception1.95683944
26MP0001984_abnormal_olfaction1.95596419
27MP0005253_abnormal_eye_physiology1.91959327
28MP0006072_abnormal_retinal_apoptosis1.91075869
29MP0001970_abnormal_pain_threshold1.86609549
30MP0002557_abnormal_social/conspecific_i1.85058057
31MP0003195_calcinosis1.84752602
32MP0006276_abnormal_autonomic_nervous1.83218590
33MP0008875_abnormal_xenobiotic_pharmacok1.81819837
34MP0002184_abnormal_innervation1.81712680
35MP0008789_abnormal_olfactory_epithelium1.78111813
36MP0008569_lethality_at_weaning1.77961708
37MP0004133_heterotaxia1.75386759
38MP0005386_behavior/neurological_phenoty1.74143977
39MP0004924_abnormal_behavior1.74143977
40MP0001529_abnormal_vocalization1.73848093
41MP0004811_abnormal_neuron_physiology1.72931620
42MP0000778_abnormal_nervous_system1.69294353
43MP0009780_abnormal_chondrocyte_physiolo1.64813781
44MP0000569_abnormal_digit_pigmentation1.63034251
45MP0004147_increased_porphyrin_level1.62992149
46MP0001293_anophthalmia1.60916060
47MP0003787_abnormal_imprinting1.60726355
48MP0003879_abnormal_hair_cell1.55556840
49MP0004858_abnormal_nervous_system1.54942692
50MP0002909_abnormal_adrenal_gland1.52042235
51MP0003122_maternal_imprinting1.44218232
52MP0003890_abnormal_embryonic-extraembry1.43649450
53MP0000955_abnormal_spinal_cord1.41266270
54MP0002066_abnormal_motor_capabilities/c1.38047501
55MP0001905_abnormal_dopamine_level1.37980778
56MP0000427_abnormal_hair_cycle1.37036508
57MP0002882_abnormal_neuron_morphology1.36945749
58MP0005645_abnormal_hypothalamus_physiol1.34442135
59MP0003718_maternal_effect1.32850535
60MP0002938_white_spotting1.31363206
61MP0004142_abnormal_muscle_tone1.30962502
62MP0000372_irregular_coat_pigmentation1.30524802
63MP0002160_abnormal_reproductive_system1.28435078
64MP0003011_delayed_dark_adaptation1.23247753
65MP0002653_abnormal_ependyma_morphology1.22382302
66MP0005410_abnormal_fertilization1.20908797
67MP0002234_abnormal_pharynx_morphology1.20080490
68MP0003329_amyloid_beta_deposits1.18325634
69MP0005195_abnormal_posterior_eye1.18198679
70MP0001502_abnormal_circadian_rhythm1.17578204
71MP0002751_abnormal_autonomic_nervous1.17381111
72MP0001986_abnormal_taste_sensitivity1.15913867
73MP0003633_abnormal_nervous_system1.15227050
74MP0005389_reproductive_system_phenotype1.15157631
75MP0002638_abnormal_pupillary_reflex1.14707914
76MP0004885_abnormal_endolymph1.14669431
77MP0002152_abnormal_brain_morphology1.14498257
78MP0005377_hearing/vestibular/ear_phenot1.13952677
79MP0003878_abnormal_ear_physiology1.13952677
80MP0005174_abnormal_tail_pigmentation1.11785446
81MP0005379_endocrine/exocrine_gland_phen1.11317540
82MP0002876_abnormal_thyroid_physiology1.06256333
83MP0005391_vision/eye_phenotype1.05858754
84MP0008872_abnormal_physiological_respon1.05517647
85MP0001929_abnormal_gametogenesis1.04614526
86MP0008058_abnormal_DNA_repair1.04559934
87MP0000631_abnormal_neuroendocrine_gland1.02247609
88MP0005394_taste/olfaction_phenotype1.00736481
89MP0005499_abnormal_olfactory_system1.00736481
90MP0008877_abnormal_DNA_methylation1.00677465
91MP0003631_nervous_system_phenotype1.00588633
92MP0009379_abnormal_foot_pigmentation0.99624994
93MP0002069_abnormal_eating/drinking_beha0.98284404
94MP0002210_abnormal_sex_determination0.94639653
95MP0004742_abnormal_vestibular_system0.93624224
96MP0004085_abnormal_heartbeat0.93270294
97MP0002163_abnormal_gland_morphology0.93262465
98MP0002095_abnormal_skin_pigmentation0.91787594
99MP0003937_abnormal_limbs/digits/tail_de0.91627825
100MP0003119_abnormal_digestive_system0.91106543
101MP0005084_abnormal_gallbladder_morpholo0.90802317
102MP0002928_abnormal_bile_duct0.90475944
103MP0002254_reproductive_system_inflammat0.90149899
104MP0001963_abnormal_hearing_physiology0.89330053
105MP0001324_abnormal_eye_pigmentation0.89068982
106MP0002233_abnormal_nose_morphology0.88877030
107MP0002229_neurodegeneration0.86899327
108MP0000013_abnormal_adipose_tissue0.86553584
109MP0008995_early_reproductive_senescence0.86425264
110MP0005367_renal/urinary_system_phenotyp0.86067682
111MP0000516_abnormal_urinary_system0.86067682
112MP0002837_dystrophic_cardiac_calcinosis0.83191102
113MP0000751_myopathy0.82862713
114MP0005551_abnormal_eye_electrophysiolog0.82821076
115MP0002752_abnormal_somatic_nervous0.79922847
116MP0008874_decreased_physiological_sensi0.78193407
117MP0005171_absent_coat_pigmentation0.77746293
118MP0003698_abnormal_male_reproductive0.77509737
119MP0003646_muscle_fatigue0.77313235
120MP0006292_abnormal_olfactory_placode0.72931084
121MP0004215_abnormal_myocardial_fiber0.72592713
122MP0001485_abnormal_pinna_reflex0.72103674
123MP0005535_abnormal_body_temperature0.71005032
124MP0004233_abnormal_muscle_weight0.70157089
125MP0001348_abnormal_lacrimal_gland0.69224114
126MP0001177_atelectasis0.68905269
127MP0003632_abnormal_nervous_system0.66669964
128MP0003861_abnormal_nervous_system0.66530115
129MP0006035_abnormal_mitochondrial_morpho0.65522001
130MP0001664_abnormal_digestion0.62616253
131MP0003634_abnormal_glial_cell0.62018063
132MP0005623_abnormal_meninges_morphology0.61968988
133MP0004043_abnormal_pH_regulation0.59687641
134MP0003121_genomic_imprinting0.58917901
135MP0002082_postnatal_lethality0.58207760
136MP0010770_preweaning_lethality0.58207760
137MP0001943_abnormal_respiration0.57291257
138MP0010769_abnormal_survival0.56908506
139MP0000026_abnormal_inner_ear0.56689110
140MP0010386_abnormal_urinary_bladder0.56605367
141MP0004145_abnormal_muscle_electrophysio0.56507957
142MP0004484_altered_response_of0.56241495
143MP0010768_mortality/aging0.54207112
144MP0003137_abnormal_impulse_conducting0.54077144

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.53596661
2Myokymia (HP:0002411)5.33301879
3Epileptic encephalopathy (HP:0200134)5.25036105
4Focal seizures (HP:0007359)5.20372613
5Atonic seizures (HP:0010819)5.11844305
6Febrile seizures (HP:0002373)4.95907076
7Pancreatic cysts (HP:0001737)4.55194948
8True hermaphroditism (HP:0010459)4.44904481
9Pancreatic fibrosis (HP:0100732)4.43532348
10Hyperventilation (HP:0002883)4.41143942
11Absence seizures (HP:0002121)4.16438017
12Visual hallucinations (HP:0002367)4.07598811
13Molar tooth sign on MRI (HP:0002419)4.05941423
14Abnormality of midbrain morphology (HP:0002418)4.05941423
15Dialeptic seizures (HP:0011146)3.85989271
16Nephronophthisis (HP:0000090)3.82132008
17Progressive cerebellar ataxia (HP:0002073)3.76078969
18Chronic hepatic failure (HP:0100626)3.72000542
19Generalized tonic-clonic seizures (HP:0002069)3.51139095
20Absent/shortened dynein arms (HP:0200106)3.40418604
21Dynein arm defect of respiratory motile cilia (HP:0012255)3.40418604
22Broad-based gait (HP:0002136)3.33715647
23Gaze-evoked nystagmus (HP:0000640)3.25803167
24Abnormality of the renal medulla (HP:0100957)3.17547944
25Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.17150991
26Abnormal ciliary motility (HP:0012262)3.10231419
27Gait imbalance (HP:0002141)3.05920979
28Congenital stationary night blindness (HP:0007642)3.05254274
29Abnormal respiratory motile cilium physiology (HP:0012261)3.03817591
30Sclerocornea (HP:0000647)3.03178992
31Cystic liver disease (HP:0006706)2.96273782
32Occipital encephalocele (HP:0002085)2.94312430
33Absent eyebrow (HP:0002223)2.92801108
34Dysdiadochokinesis (HP:0002075)2.92326096
35Impaired vibration sensation in the lower limbs (HP:0002166)2.91848026
36Medial flaring of the eyebrow (HP:0010747)2.88097992
37Poor eye contact (HP:0000817)2.82813540
38Abnormal respiratory epithelium morphology (HP:0012253)2.80766389
39Abnormal respiratory motile cilium morphology (HP:0005938)2.80766389
40Amblyopia (HP:0000646)2.80373971
41Ankle clonus (HP:0011448)2.78756189
42Congenital primary aphakia (HP:0007707)2.76251483
43Dysmetric saccades (HP:0000641)2.75622634
44Type II lissencephaly (HP:0007260)2.74337092
45Protruding tongue (HP:0010808)2.70224569
46Abnormal eating behavior (HP:0100738)2.70084150
47Truncal ataxia (HP:0002078)2.67566860
48Tubular atrophy (HP:0000092)2.67187881
49Depression (HP:0000716)2.67077605
50Excessive salivation (HP:0003781)2.65306031
51Drooling (HP:0002307)2.65306031
52Abnormality of the lower motor neuron (HP:0002366)2.62922041
53Aplasia/Hypoplasia of the tongue (HP:0010295)2.59856053
54Impaired social interactions (HP:0000735)2.56534887
55Abnormal social behavior (HP:0012433)2.56534887
56Impaired smooth pursuit (HP:0007772)2.56355356
57Action tremor (HP:0002345)2.55872378
58Nephrogenic diabetes insipidus (HP:0009806)2.55175378
59Abnormality of the renal cortex (HP:0011035)2.53562316
60Progressive inability to walk (HP:0002505)2.50589988
61Anencephaly (HP:0002323)2.50249703
62Urinary bladder sphincter dysfunction (HP:0002839)2.48924553
63Postaxial foot polydactyly (HP:0001830)2.48443572
64Bradykinesia (HP:0002067)2.43866349
65Dysmetria (HP:0001310)2.43291321
66Pendular nystagmus (HP:0012043)2.43147593
67Rhinitis (HP:0012384)2.42944422
68Genital tract atresia (HP:0001827)2.42871899
69Vaginal atresia (HP:0000148)2.41852289
70Stereotypic behavior (HP:0000733)2.39638094
71Anxiety (HP:0000739)2.39447975
72Bronchiectasis (HP:0002110)2.39206533
73Epileptiform EEG discharges (HP:0011182)2.38985926
74Pheochromocytoma (HP:0002666)2.36820010
75Abolished electroretinogram (ERG) (HP:0000550)2.36347799
76Chronic bronchitis (HP:0004469)2.34864423
77Inability to walk (HP:0002540)2.34274536
78Polydipsia (HP:0001959)2.34077274
79Abnormal drinking behavior (HP:0030082)2.34077274
80Postaxial hand polydactyly (HP:0001162)2.33592636
81Postural instability (HP:0002172)2.32877014
82Abnormal rod and cone electroretinograms (HP:0008323)2.29781339
83Abnormal hair whorl (HP:0010721)2.29238799
84Impaired vibratory sensation (HP:0002495)2.28171466
85Attenuation of retinal blood vessels (HP:0007843)2.26893784
86Anophthalmia (HP:0000528)2.25781482
87Abnormality of ocular smooth pursuit (HP:0000617)2.22890854
88Absent eyelashes (HP:0000561)2.22349949
89Focal dystonia (HP:0004373)2.21458994
90Polyphagia (HP:0002591)2.20459850
91Specific learning disability (HP:0001328)2.19210794
92Congenital hepatic fibrosis (HP:0002612)2.18302076
93Colon cancer (HP:0003003)2.18059423
94Absent speech (HP:0001344)2.17576795
95Male pseudohermaphroditism (HP:0000037)2.17267164
96Genetic anticipation (HP:0003743)2.16480106
97EEG with generalized epileptiform discharges (HP:0011198)2.16385108
98Hemiparesis (HP:0001269)2.14443061
99Absent rod-and cone-mediated responses on ERG (HP:0007688)2.13662849
100Poor coordination (HP:0002370)2.13622760
101Optic nerve hypoplasia (HP:0000609)2.12861646
102Akinesia (HP:0002304)2.12831158
103Status epilepticus (HP:0002133)2.12687374
104Acute necrotizing encephalopathy (HP:0006965)2.11261300
105Limb dystonia (HP:0002451)2.09092818
106Resting tremor (HP:0002322)2.08850183
107Neuroendocrine neoplasm (HP:0100634)2.08623239
108Annular pancreas (HP:0001734)2.08155352
109Abnormality of binocular vision (HP:0011514)2.05843359
110Diplopia (HP:0000651)2.05843359
111Hypsarrhythmia (HP:0002521)2.05113145
112Oligodactyly (hands) (HP:0001180)2.04567993
113Preaxial hand polydactyly (HP:0001177)2.04505555
114Fetal akinesia sequence (HP:0001989)2.03437879
115Decreased central vision (HP:0007663)2.03429616
116Cerebellar dysplasia (HP:0007033)2.03199906
117Furrowed tongue (HP:0000221)2.02315787
118Thickened helices (HP:0000391)2.01708914
119Abnormal biliary tract physiology (HP:0012439)2.01019570
120Bile duct proliferation (HP:0001408)2.01019570
121Urinary urgency (HP:0000012)2.00782882
122Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.99188614
123Scanning speech (HP:0002168)1.98839077
124Supranuclear gaze palsy (HP:0000605)1.98744067
125Lissencephaly (HP:0001339)1.98476813
126Craniofacial dystonia (HP:0012179)1.98056355
127Torticollis (HP:0000473)1.96855007
128Aplasia/Hypoplasia of the tibia (HP:0005772)1.96368528
129Spastic gait (HP:0002064)1.95310449
130Progressive macrocephaly (HP:0004481)1.93131515
131Failure to thrive in infancy (HP:0001531)1.92377535
132Sensory axonal neuropathy (HP:0003390)1.91537369
133Abnormality of the labia minora (HP:0012880)1.88576825
134Insidious onset (HP:0003587)1.87703374
135Termporal pattern (HP:0011008)1.87703374
136Acute encephalopathy (HP:0006846)1.86532100
137Lower limb muscle weakness (HP:0007340)1.85397027
138Mitochondrial inheritance (HP:0001427)1.83747760
139Dyskinesia (HP:0100660)1.83193866
140Methylmalonic acidemia (HP:0002912)1.82388687
141Keratoconus (HP:0000563)1.82296928
142Increased corneal curvature (HP:0100692)1.82296928
143Multicystic kidney dysplasia (HP:0000003)1.82209522
144Blue irides (HP:0000635)1.82120754
145Gastroesophageal reflux (HP:0002020)1.81982560
146Increased CSF lactate (HP:0002490)1.81220773
147Incomplete penetrance (HP:0003829)1.80270989
148Oculomotor apraxia (HP:0000657)1.79528700
149Aganglionic megacolon (HP:0002251)1.79102020
150Tubulointerstitial nephritis (HP:0001970)1.78248717
151Septo-optic dysplasia (HP:0100842)1.78015995
152Mutism (HP:0002300)1.77813404
153Aplasia/Hypoplasia of the uvula (HP:0010293)1.77003269
154Generalized myoclonic seizures (HP:0002123)1.76518971
155Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.76029575
156Abnormality of alanine metabolism (HP:0010916)1.76029575
157Hyperalaninemia (HP:0003348)1.76029575
158Abnormal mitochondria in muscle tissue (HP:0008316)1.75910002
159Polyuria (HP:0000103)1.75791156
160Narrow forehead (HP:0000341)1.75643520
161Poor suck (HP:0002033)1.75316191
162Bony spicule pigmentary retinopathy (HP:0007737)1.72909158
163Gait ataxia (HP:0002066)1.72832996
164Abnormality of the corticospinal tract (HP:0002492)1.71582782
1653-Methylglutaconic aciduria (HP:0003535)1.70554116
166Hypoplasia of the fovea (HP:0007750)1.70491034
167Aplasia/Hypoplasia of the fovea (HP:0008060)1.70491034
168Rib fusion (HP:0000902)1.68606516
169Dandy-Walker malformation (HP:0001305)1.66716381
170Retinitis pigmentosa (HP:0000510)1.64525142
171Abnormality of the pons (HP:0007361)1.63365512
172Astigmatism (HP:0000483)1.62725980

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.74868675
2AKT34.63846596
3CASK4.30482526
4NTRK33.92745287
5EPHA43.72468913
6MAP3K42.85988659
7MAP3K92.80182621
8MARK12.69170560
9MAP2K72.68163586
10MAP4K22.59458078
11BMPR1B2.53826043
12DAPK22.52904952
13PRPF4B2.43631896
14MAP3K122.19288972
15MINK12.17340297
16ZAK2.16037494
17GRK12.10120753
18CDK192.02511301
19MAPK151.94326687
20DAPK11.94079664
21NTRK21.92273260
22NUAK11.88745935
23SGK21.81032921
24PLK21.80097442
25INSRR1.76127848
26BRAF1.75707067
27MAP2K41.74673488
28WNK41.68305605
29SIK31.59669692
30ACVR1B1.59495055
31TLK11.59028420
32SGK2231.57329643
33SGK4941.57329643
34GRK51.51280394
35PDK41.50717930
36PDK31.50717930
37PAK61.46482465
38KSR11.42878090
39DYRK21.40536679
40PRKD31.38586496
41TRIM281.34238266
42TAOK31.33319054
43RIPK41.33054556
44PNCK1.32672425
45MKNK21.29044444
46CDK51.27770813
47SGK31.25102161
48MST41.23914713
49CCNB11.23805394
50PRKCG1.21854256
51MAPK131.19700805
52BRSK21.19376527
53KSR21.18362376
54STK391.18329217
55CAMKK11.18290563
56PLK41.17552501
57VRK11.15903375
58EIF2AK31.13476696
59OXSR11.12294939
60PTK2B1.11641067
61ARAF1.10922428
62TNIK1.09673844
63NTRK10.98809248
64CSNK1G10.98717993
65CAMK2A0.97495480
66STK38L0.96467861
67STK160.96221094
68BCKDK0.96056171
69ERBB30.95347081
70PLK30.90840563
71WEE10.89018658
72PIK3CA0.88220149
73CSNK1G30.86096722
74CAMKK20.85924070
75VRK20.84681172
76SIK20.82379106
77PHKG20.82050039
78PHKG10.82050039
79TYRO30.81185894
80CDK180.80909489
81BCR0.80400817
82TGFBR10.80232062
83PDK20.79051521
84CSNK1A1L0.78710029
85STK380.78027772
86MKNK10.77533864
87UHMK10.76935749
88MAP3K20.76200290
89DYRK30.75916427
90TSSK60.75494299
91FGFR20.73166987
92SGK10.71646961
93NME10.71214938
94CDK150.71073168
95CAMK2B0.70981903
96PINK10.70930282
97LMTK20.70189638
98PLK10.69338760
99DYRK1A0.68879032
100FES0.68469264
101CDK140.68465738
102BMPR20.66085285
103CDK11A0.59717462
104LATS20.58885483
105FGR0.56569693
106STK30.55675451
107PKN10.55119691
108CSNK1A10.55094879
109STK110.54732161
110CAMK10.54532200
111PRKCE0.52637179
112PRKCH0.52027345
113SRPK10.50814789
114CHEK20.48187822
115NEK10.47879302
116WNK30.47187401
117TIE10.46320067
118RAF10.43639776
119RPS6KA30.42810419
120CDK30.42446755
121PRKCI0.42380635
122CAMK40.42360356
123DAPK30.42241296
124ADRBK20.41971899
125ATR0.41762748
126PDK10.41636662
127MUSK0.41395356
128MAP3K60.40312477
129GRK70.39419254
130YES10.38959211
131MAPKAPK50.37024933
132PRKCQ0.36911867
133PASK0.36905997
134MAP3K10.36358307
135TNK20.35387124
136CAMK2G0.35162213
137OBSCN0.34769708
138ATM0.34606856
139ADRBK10.34199109
140MARK20.34119284
141EPHB20.34099491
142MAP3K130.33894162
143PRKCZ0.33839718
144PRKG10.33811394
145LIMK10.33542935
146PRKACB0.33009305
147MAPK100.32788655
148PAK30.32071528
149RPS6KA50.31912937
150MAP2K10.31775661
151PRKCB0.31657247
152CSNK1G20.31474967
153CAMK2D0.31376297
154TAF10.31220226
155PRKACA0.31104036
156FER0.30756260
157CSNK1D0.30740173
158MAPK70.30117148
159PRKCA0.29739301
160PDPK10.29052548

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.25677426
2Synaptic vesicle cycle_Homo sapiens_hsa047213.87416207
3Olfactory transduction_Homo sapiens_hsa047403.11696965
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.84462555
5GABAergic synapse_Homo sapiens_hsa047272.83123492
6Long-term potentiation_Homo sapiens_hsa047202.79384959
7Morphine addiction_Homo sapiens_hsa050322.73753273
8Amphetamine addiction_Homo sapiens_hsa050312.68958341
9Circadian entrainment_Homo sapiens_hsa047132.64182435
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.56680105
11Collecting duct acid secretion_Homo sapiens_hsa049662.55413465
12Glutamatergic synapse_Homo sapiens_hsa047242.52881615
13Protein export_Homo sapiens_hsa030602.37745728
14Linoleic acid metabolism_Homo sapiens_hsa005912.24036769
15Dopaminergic synapse_Homo sapiens_hsa047282.23520186
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.23438552
17Fanconi anemia pathway_Homo sapiens_hsa034602.07552641
18Butanoate metabolism_Homo sapiens_hsa006502.06850049
19Caffeine metabolism_Homo sapiens_hsa002321.99602240
20Salivary secretion_Homo sapiens_hsa049701.96253812
21Taste transduction_Homo sapiens_hsa047421.91291304
22Homologous recombination_Homo sapiens_hsa034401.89918321
23Basal transcription factors_Homo sapiens_hsa030221.87592843
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.87181903
25Insulin secretion_Homo sapiens_hsa049111.86529964
26Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.84135981
27Serotonergic synapse_Homo sapiens_hsa047261.83169085
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.82557815
29Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.82133871
30Nitrogen metabolism_Homo sapiens_hsa009101.79183598
31Propanoate metabolism_Homo sapiens_hsa006401.74586261
32Long-term depression_Homo sapiens_hsa047301.73641224
33Renin secretion_Homo sapiens_hsa049241.69908049
34Gastric acid secretion_Homo sapiens_hsa049711.69309757
35Cholinergic synapse_Homo sapiens_hsa047251.67893705
36Calcium signaling pathway_Homo sapiens_hsa040201.67021122
37Cocaine addiction_Homo sapiens_hsa050301.62503124
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.55134599
39RNA degradation_Homo sapiens_hsa030181.50362643
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.49489703
41Oxytocin signaling pathway_Homo sapiens_hsa049211.48756947
42RNA polymerase_Homo sapiens_hsa030201.47557406
43Vibrio cholerae infection_Homo sapiens_hsa051101.46813069
44Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.41804221
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.40332993
46Selenocompound metabolism_Homo sapiens_hsa004501.40181921
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36730654
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.35011086
49Regulation of autophagy_Homo sapiens_hsa041401.34999506
50Peroxisome_Homo sapiens_hsa041461.29732745
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29327964
52Chemical carcinogenesis_Homo sapiens_hsa052041.27951283
53Ether lipid metabolism_Homo sapiens_hsa005651.22761978
54Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.21503471
55cAMP signaling pathway_Homo sapiens_hsa040241.20140883
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.19949400
57Gap junction_Homo sapiens_hsa045401.19081355
58Tryptophan metabolism_Homo sapiens_hsa003801.16784953
59GnRH signaling pathway_Homo sapiens_hsa049121.16251637
60Steroid biosynthesis_Homo sapiens_hsa001001.16002746
61Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.12969816
62Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12211740
63Retinol metabolism_Homo sapiens_hsa008301.10764328
64Cardiac muscle contraction_Homo sapiens_hsa042601.09546566
65Oxidative phosphorylation_Homo sapiens_hsa001901.07149119
66Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06597895
67Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06385321
68Phototransduction_Homo sapiens_hsa047441.06372900
69ErbB signaling pathway_Homo sapiens_hsa040121.06177467
70Primary bile acid biosynthesis_Homo sapiens_hsa001201.04352147
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.03732609
72Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01442510
73Axon guidance_Homo sapiens_hsa043601.01142548
74ABC transporters_Homo sapiens_hsa020101.00844502
75Melanogenesis_Homo sapiens_hsa049161.00789291
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.99757902
77Glioma_Homo sapiens_hsa052140.98183329
78beta-Alanine metabolism_Homo sapiens_hsa004100.97992627
79Oocyte meiosis_Homo sapiens_hsa041140.97438026
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.96674818
81Estrogen signaling pathway_Homo sapiens_hsa049150.95055255
82Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.92762858
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.90478663
84Type II diabetes mellitus_Homo sapiens_hsa049300.89168396
85Non-homologous end-joining_Homo sapiens_hsa034500.88215682
86Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.88030386
87cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87480629
88Vascular smooth muscle contraction_Homo sapiens_hsa042700.86465785
89Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84804838
90Arachidonic acid metabolism_Homo sapiens_hsa005900.83850023
91Mismatch repair_Homo sapiens_hsa034300.83517955
92Nucleotide excision repair_Homo sapiens_hsa034200.82263500
93Alzheimers disease_Homo sapiens_hsa050100.79809741
94Histidine metabolism_Homo sapiens_hsa003400.76761147
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.76338352
96Purine metabolism_Homo sapiens_hsa002300.75920675
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.74895768
98Parkinsons disease_Homo sapiens_hsa050120.74294831
99Proteasome_Homo sapiens_hsa030500.73951392
100Glucagon signaling pathway_Homo sapiens_hsa049220.72923097
101Huntingtons disease_Homo sapiens_hsa050160.71404437
102MAPK signaling pathway_Homo sapiens_hsa040100.69847631
103Dorso-ventral axis formation_Homo sapiens_hsa043200.69066461
104Metabolic pathways_Homo sapiens_hsa011000.69018846
105Vitamin digestion and absorption_Homo sapiens_hsa049770.67833541
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67562147
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67331572
108Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.65611554
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64328849
110Type I diabetes mellitus_Homo sapiens_hsa049400.63186423
111Alcoholism_Homo sapiens_hsa050340.62015333
112One carbon pool by folate_Homo sapiens_hsa006700.58996484
113Fatty acid elongation_Homo sapiens_hsa000620.56601434
114Pyrimidine metabolism_Homo sapiens_hsa002400.53852504
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.52493035
116Sulfur relay system_Homo sapiens_hsa041220.52393699
117Sulfur metabolism_Homo sapiens_hsa009200.52193808
118Wnt signaling pathway_Homo sapiens_hsa043100.52130807
119Basal cell carcinoma_Homo sapiens_hsa052170.51692126
120Pancreatic secretion_Homo sapiens_hsa049720.50690840
121Dilated cardiomyopathy_Homo sapiens_hsa054140.50645741
122Tyrosine metabolism_Homo sapiens_hsa003500.50617124
123RNA transport_Homo sapiens_hsa030130.49873624
124Circadian rhythm_Homo sapiens_hsa047100.49645450
125Ras signaling pathway_Homo sapiens_hsa040140.49178826
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49030366
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.48628876
128Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47646173
129Glutathione metabolism_Homo sapiens_hsa004800.47606592
130Rheumatoid arthritis_Homo sapiens_hsa053230.47471540
131Fat digestion and absorption_Homo sapiens_hsa049750.47279953
132Thyroid hormone synthesis_Homo sapiens_hsa049180.46987496
133Inositol phosphate metabolism_Homo sapiens_hsa005620.46788036
134Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46199411
135Neurotrophin signaling pathway_Homo sapiens_hsa047220.44284833
136Rap1 signaling pathway_Homo sapiens_hsa040150.44128296
137Choline metabolism in cancer_Homo sapiens_hsa052310.43693559
138Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43412242
139mTOR signaling pathway_Homo sapiens_hsa041500.43125657
140Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42633606
141Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.42260869
142Insulin signaling pathway_Homo sapiens_hsa049100.41994592
143Ovarian steroidogenesis_Homo sapiens_hsa049130.41747479
144Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41082278
145Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40706613
146Fatty acid degradation_Homo sapiens_hsa000710.40212382
147Ribosome_Homo sapiens_hsa030100.38382796
148Renal cell carcinoma_Homo sapiens_hsa052110.37771890
149Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.36355884
150Endometrial cancer_Homo sapiens_hsa052130.36125193
151Hippo signaling pathway_Homo sapiens_hsa043900.36026005
152p53 signaling pathway_Homo sapiens_hsa041150.35507353
153Pyruvate metabolism_Homo sapiens_hsa006200.34644752
154SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32873345
155Hedgehog signaling pathway_Homo sapiens_hsa043400.31461475
1562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31209653
157Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31069214
158Melanoma_Homo sapiens_hsa052180.30678950
159Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.30393806
160Colorectal cancer_Homo sapiens_hsa052100.30040852
161Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.29839876
162Non-small cell lung cancer_Homo sapiens_hsa052230.29835247
163Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29418230
164African trypanosomiasis_Homo sapiens_hsa051430.28409362
165Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28215978
166Phagosome_Homo sapiens_hsa041450.27983826
167VEGF signaling pathway_Homo sapiens_hsa043700.27750272

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