ANKRD53

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.74362042
2axonemal dynein complex assembly (GO:0070286)9.69819560
3motile cilium assembly (GO:0044458)9.63686588
4spermatid development (GO:0007286)9.48143244
5epithelial cilium movement (GO:0003351)9.19719696
6reproduction (GO:0000003)8.73443656
7regulation of cilium movement (GO:0003352)8.70307922
8cilium or flagellum-dependent cell motility (GO:0001539)8.43405320
9response to pheromone (GO:0019236)8.28080123
10cilium movement (GO:0003341)7.44468878
11phosphatidylethanolamine biosynthetic process (GO:0006646)7.22960236
12negative regulation of inclusion body assembly (GO:0090084)7.20150525
13piRNA metabolic process (GO:0034587)7.17011530
14epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.99691155
15single fertilization (GO:0007338)6.94582080
16sperm capacitation (GO:0048240)6.89522156
17synaptonemal complex organization (GO:0070193)6.80044243
18rRNA methylation (GO:0031167)6.64764883
19synaptonemal complex assembly (GO:0007130)6.62315375
20phosphatidylethanolamine metabolic process (GO:0046337)6.60346184
21spermatogenesis (GO:0007283)6.56525032
22male gamete generation (GO:0048232)6.53998779
23male meiosis (GO:0007140)6.51574002
24microtubule depolymerization (GO:0007019)6.41967129
25organic cation transport (GO:0015695)6.40091577
26gamete generation (GO:0007276)6.00676001
27fertilization (GO:0009566)5.96887411
28regulation of inclusion body assembly (GO:0090083)5.88018364
29calcium ion-dependent exocytosis (GO:0017156)5.82883384
30protein targeting to Golgi (GO:0000042)5.72287063
31rRNA modification (GO:0000154)5.49681812
32establishment of protein localization to Golgi (GO:0072600)5.48113810
33retrograde transport, vesicle recycling within Golgi (GO:0000301)5.45719476
34germ cell development (GO:0007281)5.30671050
35cellular process involved in reproduction in multicellular organism (GO:0022412)5.29934501
36regulation of microtubule-based movement (GO:0060632)5.18919690
37positive regulation of Rab GTPase activity (GO:0032851)5.10639767
38regulation of Rab GTPase activity (GO:0032313)5.10639767
39chromosome condensation (GO:0030261)5.04320538
40cell recognition (GO:0008037)5.00070986
41ventricular system development (GO:0021591)4.98525594
42microtubule severing (GO:0051013)4.90208341
43DNA packaging (GO:0006323)4.84764191
44cellular ketone body metabolic process (GO:0046950)4.75859288
45multicellular organismal reproductive process (GO:0048609)4.72879331
46DNA methylation involved in gamete generation (GO:0043046)4.66367805
47seminiferous tubule development (GO:0072520)4.63359491
48left/right pattern formation (GO:0060972)4.60183863
49male meiosis I (GO:0007141)4.57530098
50protein localization to Golgi apparatus (GO:0034067)4.56388849
51regulation of transcription involved in cell fate commitment (GO:0060850)4.46333667
52spermatid nucleus differentiation (GO:0007289)4.45985435
53glycerol ether metabolic process (GO:0006662)4.39582412
54chromosome organization involved in meiosis (GO:0070192)4.38556711
55ketone body metabolic process (GO:1902224)4.20015352
56centriole replication (GO:0007099)4.07309709
57ether metabolic process (GO:0018904)4.04436734
58meiotic nuclear division (GO:0007126)4.01276058
59chaperone-mediated protein complex assembly (GO:0051131)3.96496839
60antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.94769129
61negative regulation of Rho protein signal transduction (GO:0035024)3.89610906
62coenzyme catabolic process (GO:0009109)3.87747530
63multicellular organismal development (GO:0007275)3.84128861
64protein polyglutamylation (GO:0018095)3.77910266
65centriole assembly (GO:0098534)3.69146599
66cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.66876845
67meiosis I (GO:0007127)3.63155180
68cranial nerve morphogenesis (GO:0021602)3.57000952
69sexual reproduction (GO:0019953)3.48613494
70multicellular organismal movement (GO:0050879)3.41515449
71musculoskeletal movement (GO:0050881)3.41515449
72RNA localization (GO:0006403)3.40958247
73protein localization to cilium (GO:0061512)3.39532137
74cellular response to pH (GO:0071467)3.39180026
75mitotic sister chromatid cohesion (GO:0007064)3.37527863
76meiotic cell cycle (GO:0051321)3.33259264
77regulation of spindle checkpoint (GO:0090231)3.33185182
78genitalia morphogenesis (GO:0035112)3.32881263
79single strand break repair (GO:0000012)3.28295564
80microtubule polymerization or depolymerization (GO:0031109)3.24834736
81peptidyl-threonine dephosphorylation (GO:0035970)3.21656639
82membrane protein intracellular domain proteolysis (GO:0031293)3.19110896
83amino-acid betaine transport (GO:0015838)3.17148528
84carnitine transport (GO:0015879)3.17148528
85monoubiquitinated protein deubiquitination (GO:0035520)3.16567491
86RNA destabilization (GO:0050779)3.14786523
87glycolytic process (GO:0006096)3.14639026
88mitochondrion degradation (GO:0000422)3.12507749
89nucleus organization (GO:0006997)3.10831743
90polyol catabolic process (GO:0046174)3.06046603
91regulation of T-helper 2 cell differentiation (GO:0045628)3.05679910
92negative regulation of organelle assembly (GO:1902116)3.05123947
93protein refolding (GO:0042026)3.04094615
94protein K11-linked deubiquitination (GO:0035871)3.03935288
95interferon-gamma secretion (GO:0072643)3.03420146
96carnitine transmembrane transport (GO:1902603)3.03356055
97regulation of interleukin-13 production (GO:0032656)3.02855998
98sequestering of actin monomers (GO:0042989)3.00248277
99regulation of cilium assembly (GO:1902017)2.99612157
100gene silencing by RNA (GO:0031047)2.96156240
101glomerular epithelial cell development (GO:0072310)2.94585630
102protein-DNA complex disassembly (GO:0032986)2.94191716
103nucleosome disassembly (GO:0006337)2.94191716
104tooth mineralization (GO:0034505)2.91753875
105cell differentiation involved in metanephros development (GO:0072202)2.87505154
106metanephric mesenchyme development (GO:0072075)2.85444660
107receptor recycling (GO:0001881)2.85401980
108mesenchymal cell differentiation involved in renal system development (GO:2001012)2.85122370
109mesenchymal cell differentiation involved in kidney development (GO:0072161)2.85122370
110glomerular visceral epithelial cell development (GO:0072015)2.81549534
111peristalsis (GO:0030432)2.80851770
112microtubule-based movement (GO:0007018)2.79850329
113protein depolymerization (GO:0051261)2.79045094
114peptidyl-proline hydroxylation (GO:0019511)2.77956597
115microtubule nucleation (GO:0007020)2.77817510
116regulation of somitogenesis (GO:0014807)2.76483661
117alanine transport (GO:0032328)2.75405516
118positive regulation of macrophage activation (GO:0043032)2.72812092
119chromatin silencing (GO:0006342)2.71523034
120cerebral cortex neuron differentiation (GO:0021895)2.71019407
121gene silencing (GO:0016458)2.70873580
122homeostasis of number of cells within a tissue (GO:0048873)2.70046294
123alditol metabolic process (GO:0019400)2.69918583
124peptidyl-glutamic acid modification (GO:0018200)2.67072540
125cilium organization (GO:0044782)2.66221123
126meiotic cell cycle process (GO:1903046)2.64240630
127cilium morphogenesis (GO:0060271)2.61137046
128response to acidic pH (GO:0010447)2.60656626
129cilium assembly (GO:0042384)2.56156831
130cellular component assembly involved in morphogenesis (GO:0010927)2.53503378
131axoneme assembly (GO:0035082)2.53126557
132nucleoside diphosphate phosphorylation (GO:0006165)2.50166827
133polyamine biosynthetic process (GO:0006596)2.49445666
134calcium ion import (GO:0070509)2.42533164
135synapsis (GO:0007129)2.40587755
136sperm motility (GO:0030317)13.4177799
137fusion of sperm to egg plasma membrane (GO:0007342)12.7300780
138cell wall macromolecule catabolic process (GO:0016998)12.4196582
139cell wall macromolecule metabolic process (GO:0044036)12.4196582
140acrosome reaction (GO:0007340)12.0700184
141sperm-egg recognition (GO:0035036)11.1979763
142acrosome assembly (GO:0001675)10.9403260
143multicellular organism reproduction (GO:0032504)10.2339513
144binding of sperm to zona pellucida (GO:0007339)10.1881599
145cell-cell recognition (GO:0009988)10.0615469

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.43539757
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.44025723
3EZH2_22144423_ChIP-Seq_EOC_Human4.46690198
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.37673550
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.33466388
6STAT6_21828071_ChIP-Seq_BEAS2B_Human3.23600860
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.83930994
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.54843953
9* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.40801779
10GATA1_26923725_Chip-Seq_HPCs_Mouse2.25663952
11ZNF274_21170338_ChIP-Seq_K562_Hela2.20379226
12DROSHA_22980978_ChIP-Seq_HELA_Human2.19242577
13ELK4_26923725_Chip-Seq_MESODERM_Mouse2.00940717
14VDR_22108803_ChIP-Seq_LS180_Human1.97827221
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90359420
16FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.87865412
17LXR_22292898_ChIP-Seq_THP-1_Human1.76737298
18* ERA_21632823_ChIP-Seq_H3396_Human1.76172703
19EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.75196928
20EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.74973172
21RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.72878910
22WDR5_24793694_ChIP-Seq_LNCAP_Human1.70404817
23MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.69777728
24* P68_20966046_ChIP-Seq_HELA_Human1.69286427
25NANOG_20526341_ChIP-Seq_ESCs_Human1.67291238
26TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65894696
27REST_21632747_ChIP-Seq_MESCs_Mouse1.65653690
28RAC3_21632823_ChIP-Seq_H3396_Human1.62603520
29KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.61902488
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60005158
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57357974
32GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.56853217
33TP63_22573176_ChIP-Seq_HFKS_Human1.54932730
34TAF2_19829295_ChIP-Seq_ESCs_Human1.53824861
35* STAT1_17558387_ChIP-Seq_HELA_Human1.52933748
36SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.48561989
37THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.47908633
38* FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.47083724
39DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.46754189
40FLI1_27457419_Chip-Seq_LIVER_Mouse1.46098324
41GATA3_21867929_ChIP-Seq_CD8_Mouse1.45127796
42SOX2_22085726_ChIP-Seq_NPCs_Mouse1.44685968
43SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44679885
44* P300_27268052_Chip-Seq_Bcells_Human1.43087128
45* VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.41533056
46SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.41266142
47* EZH2_27294783_Chip-Seq_ESCs_Mouse1.41249267
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39865078
49LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.39696407
50E2F1_20622854_ChIP-Seq_HELA_Human1.39165901
51TP53_18474530_ChIP-ChIP_U2OS_Human1.38597501
52TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36451768
53PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.35736585
54MYC_19829295_ChIP-Seq_ESCs_Human1.35561740
55P53_21459846_ChIP-Seq_SAOS-2_Human1.35242691
56CBP_20019798_ChIP-Seq_JUKART_Human1.33185466
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.33185466
58KDM2B_26808549_Chip-Seq_REH_Human1.31800590
59* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.30056342
60P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.29913800
61RARG_19884340_ChIP-ChIP_MEFs_Mouse1.28800158
62RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.28512464
63GATA1_19941826_ChIP-Seq_K562_Human1.28046162
64SA1_27219007_Chip-Seq_Bcells_Human1.26772505
65* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.24322215
66JARID2_20075857_ChIP-Seq_MESCs_Mouse1.24261742
67SA1_27219007_Chip-Seq_ERYTHROID_Human1.23635538
68ARNT_22903824_ChIP-Seq_MCF-7_Human1.23241619
69PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.23239923
70ETV2_25802403_ChIP-Seq_MESCs_Mouse1.22689969
71FLI1_21867929_ChIP-Seq_TH2_Mouse1.22295930
72AUTS2_25519132_ChIP-Seq_293T-REX_Human1.22295282
73OCT4_20526341_ChIP-Seq_ESCs_Human1.21075902
74TET1_21451524_ChIP-Seq_MESCs_Mouse1.19830855
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.17773690
76CEBPB_22108803_ChIP-Seq_LS180_Human1.17705621
77GATA3_21867929_ChIP-Seq_TH1_Mouse1.17532596
78EED_16625203_ChIP-ChIP_MESCs_Mouse1.17411178
79TAL1_26923725_Chip-Seq_HPCs_Mouse1.17228884
80GF1_26923725_Chip-Seq_HPCs_Mouse1.16756106
81SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16730602
82MYC_27129775_Chip-Seq_CORNEA_Mouse1.16141862
83NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.15921323
84MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.15633456
85PCGF2_27294783_Chip-Seq_ESCs_Mouse1.15513856
86ELF1_20517297_ChIP-Seq_JURKAT_Human1.15301725
87AR_25329375_ChIP-Seq_VCAP_Human1.14330676
88RUNX1_26923725_Chip-Seq_HPCs_Mouse1.13464844
89* GATA3_21878914_ChIP-Seq_MCF-7_Human1.13140036
90SMRT_27268052_Chip-Seq_Bcells_Human1.12909177
91ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12575875
92HNFA_21074721_ChIP-Seq_CACO-2_Human1.11840782
93CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10734459
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10690951
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10511737
96GATA1_19941827_ChIP-Seq_MEL86_Mouse1.10468532
97RAD21_21589869_ChIP-Seq_MESCs_Mouse1.08519407
98CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08421126
99SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.08228410
100RBPJ_21746931_ChIP-Seq_IB4_Human1.07956488
101CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.07537887
102CBX2_22325352_ChIP-Seq_293T-Rex_Human1.07436663
103NFIB_24661679_ChIP-Seq_LUNG_Mouse1.07058875
104SPI1_26923725_Chip-Seq_HPCs_Mouse1.06381395
105EZH2_27304074_Chip-Seq_ESCs_Mouse1.06311442
106UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06269994
107* OCT4_19829295_ChIP-Seq_ESCs_Human1.05225673
108CTCF_20526341_ChIP-Seq_ESCs_Human1.04878696
109RARA_24833708_ChIP-Seq_LIVER_Mouse1.04733521
110* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.04715058
111TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04564516
112POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04564516
113YY1_22570637_ChIP-Seq_MALME-3M_Human1.04263602
114EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.03966735
115SMAD4_21741376_ChIP-Seq_EPCs_Human1.03643420
116CBX2_27304074_Chip-Seq_ESCs_Mouse1.03492885
117RXRA_24833708_ChIP-Seq_LIVER_Mouse1.02543145
118* CTCF_21964334_Chip-Seq_Bcells_Human1.02233415
119JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02188525
120ETV1_20927104_ChIP-Seq_GIST48_Human1.02098226
121ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.01052986
122* TDRD3_21172665_ChIP-Seq_MCF-7_Human1.00986282
123JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.00153746
124PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00007143
125RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99081951
126KAP1_22055183_ChIP-Seq_ESCs_Mouse0.98991252
127SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98318732
128MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.98139197
129SMC4_20622854_ChIP-Seq_HELA_Human0.96939175
130PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.96909865
131CSB_26484114_Chip-Seq_FIBROBLAST_Human0.96854844
132TBL1_22424771_ChIP-Seq_293T_Human0.96805236
133PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96676175
134EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96044859
135SMAD4_21741376_ChIP-Seq_HESCs_Human0.95235240
136* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.94673405
137NFYB_21822215_ChIP-Seq_K562_Human0.94491679
138FUS_26573619_Chip-Seq_HEK293_Human0.93973756
139* MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93712832
140PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.93454893
141KLF4_19829295_ChIP-Seq_ESCs_Human0.92899874
142FLI1_21867929_ChIP-Seq_CD8_Mouse0.92611899
143BMI1_23680149_ChIP-Seq_NPCS_Mouse0.92432252
144* BCOR_27268052_Chip-Seq_Bcells_Human0.91922027
145TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91820469
146BCL6_27268052_Chip-Seq_Bcells_Human0.91402454
147NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.90899030
148EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.90892821
149SOX2_21211035_ChIP-Seq_LN229_Human0.90637877
150SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.90527787
151SOX11_22085726_ChIP-Seq_ESNs_Mouse0.90276988
152SMAD3_21741376_ChIP-Seq_ESCs_Human0.89586210
153NFE2_27457419_Chip-Seq_LIVER_Mouse0.89464414
154* PHF8_20622854_ChIP-Seq_HELA_Human0.89140574
155* CTCF_27219007_Chip-Seq_Bcells_Human0.89118381
156KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.88690075
157SOX9_26525672_Chip-Seq_HEART_Mouse0.88239724
158ERG_20517297_ChIP-Seq_VCAP_Human0.86889053
159ESET_19884257_ChIP-Seq_ESCs_Mouse0.86350539
160TAF15_26573619_Chip-Seq_HEK293_Human0.83702708
161SRY_22984422_ChIP-ChIP_TESTIS_Rat0.83494203
162EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.83293492
163CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.83041001
164CRX_20693478_ChIP-Seq_RETINA_Mouse0.82635181
165LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.82281063

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.84096607
2MP0001929_abnormal_gametogenesis5.23325390
3MP0001348_abnormal_lacrimal_gland4.00713368
4MP0008877_abnormal_DNA_methylation3.98551180
5MP0002161_abnormal_fertility/fecundity3.20100160
6MP0002210_abnormal_sex_determination3.11932604
7MP0001145_abnormal_male_reproductive2.67543003
8MP0005670_abnormal_white_adipose2.59748898
9MP0002653_abnormal_ependyma_morphology2.44535847
10MP0000653_abnormal_sex_gland2.28890899
11MP0000678_abnormal_parathyroid_gland2.27198784
12MP0002132_abnormal_respiratory_system2.00270129
13MP0005410_abnormal_fertilization15.9818040
14MP0001905_abnormal_dopamine_level1.96538053
15MP0002138_abnormal_hepatobiliary_system1.92866328
16MP0004233_abnormal_muscle_weight1.87603020
17MP0002735_abnormal_chemical_nociception1.87546639
18MP0003646_muscle_fatigue1.68246311
19MP0002160_abnormal_reproductive_system1.58621633
20MP0002249_abnormal_larynx_morphology1.53355822
21MP0005167_abnormal_blood-brain_barrier1.52471261
22MP0005623_abnormal_meninges_morphology1.40432053
23MP0003718_maternal_effect1.40186369
24MP0001984_abnormal_olfaction1.33578594
25MP0009046_muscle_twitch1.33084076
26MP0005248_abnormal_Harderian_gland1.30580809
27MP0005379_endocrine/exocrine_gland_phen1.27650380
28MP0004510_myositis1.19653074
29MP0000569_abnormal_digit_pigmentation1.18428725
30MP0009053_abnormal_anal_canal1.17991672
31MP0005083_abnormal_biliary_tract1.16927225
32MP0002127_abnormal_cardiovascular_syste1.06465224
33MP0002234_abnormal_pharynx_morphology1.06436881
34MP0002282_abnormal_trachea_morphology1.06338339
35MP0005310_abnormal_salivary_gland1.05353399
36MP0000681_abnormal_thyroid_gland1.05201799
37MP0001879_abnormal_lymphatic_vessel1.04411402
38MP0005375_adipose_tissue_phenotype1.01568705
39MP0000026_abnormal_inner_ear0.99674508
40MP0001765_abnormal_ion_homeostasis0.97871458
41MP0005535_abnormal_body_temperature0.97002342
42MP0001299_abnormal_eye_distance/0.96708381
43MP0003880_abnormal_central_pattern0.96640540
44MP0003115_abnormal_respiratory_system0.96272611
45MP0010329_abnormal_lipoprotein_level0.96129956
46MP0004859_abnormal_synaptic_plasticity0.94611126
47MP0002733_abnormal_thermal_nociception0.93650557
48MP0006292_abnormal_olfactory_placode0.89099704
49MP0000249_abnormal_blood_vessel0.87717954
50MP0005503_abnormal_tendon_morphology0.87070614
51MP0003787_abnormal_imprinting0.85880573
52MP0000049_abnormal_middle_ear0.85114933
53MP0005367_renal/urinary_system_phenotyp0.84316137
54MP0000516_abnormal_urinary_system0.84316137
55MP0005423_abnormal_somatic_nervous0.83325805
56MP0000003_abnormal_adipose_tissue0.83069784
57MP0003329_amyloid_beta_deposits0.79930938
58MP0001963_abnormal_hearing_physiology0.79557196
59MP0008569_lethality_at_weaning0.73930780
60MP0001485_abnormal_pinna_reflex0.72043661
61MP0005551_abnormal_eye_electrophysiolog0.72014046
62MP0003635_abnormal_synaptic_transmissio0.71665265
63MP0005389_reproductive_system_phenotype0.69090512
64MP0004085_abnormal_heartbeat0.68929438
65MP0004811_abnormal_neuron_physiology0.68730497
66MP0002734_abnormal_mechanical_nocicepti0.67398065
67MP0008789_abnormal_olfactory_epithelium0.66303739
68MP0009840_abnormal_foam_cell0.65380193
69MP0010386_abnormal_urinary_bladder0.65117952
70MP0009278_abnormal_bone_marrow0.63540742
71MP0002736_abnormal_nociception_after0.61411345
72MP0004270_analgesia0.61334289
73MP0001970_abnormal_pain_threshold0.61307951
74MP0005395_other_phenotype0.61198745
75MP0006276_abnormal_autonomic_nervous0.59805692
76MP0003879_abnormal_hair_cell0.58179541
77MP0001346_abnormal_lacrimal_gland0.57404046
78MP0001529_abnormal_vocalization0.57402637
79MP0005377_hearing/vestibular/ear_phenot0.56843692
80MP0003878_abnormal_ear_physiology0.56843692
81MP0002063_abnormal_learning/memory/cond0.56340177
82MP0003119_abnormal_digestive_system0.55859679
83MP0001666_abnormal_nutrient_absorption0.54976031
84MP0002269_muscular_atrophy0.54971359
85MP0005253_abnormal_eye_physiology0.54961809
86MP0008961_abnormal_basal_metabolism0.54477903
87MP0001968_abnormal_touch/_nociception0.53969867
88MP0001958_emphysema0.53536585
89MP0005275_abnormal_skin_tensile0.52060277
90MP0005666_abnormal_adipose_tissue0.51615403
91MP0002822_catalepsy0.51119157
92MP0005595_abnormal_vascular_smooth0.50691194
93MP0008995_early_reproductive_senescence0.50512577
94MP0002152_abnormal_brain_morphology0.50213055
95MP0005397_hematopoietic_system_phenotyp0.49690342
96MP0001545_abnormal_hematopoietic_system0.49690342
97MP0008058_abnormal_DNA_repair0.48936329
98MP0002572_abnormal_emotion/affect_behav0.48747669
99MP0003638_abnormal_response/metabolism_0.48143329
100MP0000534_abnormal_ureter_morphology0.46946910
101MP0003633_abnormal_nervous_system0.46876734
102MP0000358_abnormal_cell_content/0.46719142
103MP0000163_abnormal_cartilage_morphology0.46536297
104MP0003861_abnormal_nervous_system0.46392873
105MP0003279_aneurysm0.46368218
106MP0001324_abnormal_eye_pigmentation0.46270520
107MP0005647_abnormal_sex_gland0.45623142
108MP0003091_abnormal_cell_migration0.45614638
109MP0002970_abnormal_white_adipose0.45567857
110MP0002909_abnormal_adrenal_gland0.45363775
111MP0005334_abnormal_fat_pad0.45314811
112MP0010094_abnormal_chromosome_stability0.44947715
113MP0002295_abnormal_pulmonary_circulatio0.44847659
114MP0002272_abnormal_nervous_system0.43680027
115MP0004036_abnormal_muscle_relaxation0.43343850
116MP0003111_abnormal_nucleus_morphology0.42691134
117MP0006072_abnormal_retinal_apoptosis0.42312774
118MP0001293_anophthalmia0.41844723
119MP0004808_abnormal_hematopoietic_stem0.41769430
120MP0002928_abnormal_bile_duct0.41568255
121MP0003045_fibrosis0.40981626
122MP0003011_delayed_dark_adaptation0.39567772
123MP0003699_abnormal_female_reproductive0.39285043
124MP0001440_abnormal_grooming_behavior0.39200596
125MP0001730_embryonic_growth_arrest0.38388490
126MP0010307_abnormal_tumor_latency0.37292305
127MP0003631_nervous_system_phenotype0.36918001
128MP0009745_abnormal_behavioral_response0.36382880
129MP0005391_vision/eye_phenotype0.36134043
130MP0004742_abnormal_vestibular_system0.35202189
131MP0002064_seizures0.35000884
132MP0004145_abnormal_muscle_electrophysio0.34385508
133MP0000604_amyloidosis0.34222693
134MP0002169_no_abnormal_phenotype0.33617948
135MP0002873_normal_phenotype0.33509657
136MP0002229_neurodegeneration0.33055989
137MP0000955_abnormal_spinal_cord0.32893838
138MP0009115_abnormal_fat_cell0.32419545
139MP0002067_abnormal_sensory_capabilities0.31237726
140MP0002882_abnormal_neuron_morphology0.30815335
141MP0000751_myopathy0.30526328
142MP0008770_decreased_survivor_rate0.30177868
143MP0003948_abnormal_gas_homeostasis0.30171578
144MP0005636_abnormal_mineral_homeostasis0.29912491
145MP0001849_ear_inflammation0.29837872
146MP0003942_abnormal_urinary_system0.29502585
147MP0003950_abnormal_plasma_membrane0.28649215
148MP0002557_abnormal_social/conspecific_i0.27114723
149MP0002971_abnormal_brown_adipose0.26652573
150MP0001661_extended_life_span0.26490142
151MP0000015_abnormal_ear_pigmentation0.24942032
152MP0001486_abnormal_startle_reflex0.24715066
153MP0004130_abnormal_muscle_cell0.24610828
154MP0005195_abnormal_posterior_eye0.24201649
155MP0002066_abnormal_motor_capabilities/c0.24006133
156MP0003959_abnormal_lean_body0.23445772

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)8.73011184
2Abnormal respiratory motile cilium morphology (HP:0005938)8.73011184
3Abnormal respiratory motile cilium physiology (HP:0012261)8.66571635
4Rhinitis (HP:0012384)7.27369613
5Severe visual impairment (HP:0001141)7.21131001
6Chronic bronchitis (HP:0004469)6.94819497
7Infertility (HP:0000789)6.92552963
8Nasal polyposis (HP:0100582)6.60696874
9Abnormal ciliary motility (HP:0012262)6.40196360
10Abnormality of the nasal mucosa (HP:0000433)5.38244494
11Attenuation of retinal blood vessels (HP:0007843)4.77086429
12Bronchitis (HP:0012387)4.76693394
13Male infertility (HP:0003251)4.74627345
14Bony spicule pigmentary retinopathy (HP:0007737)4.72937258
15Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.55831189
16Bronchiectasis (HP:0002110)4.41459452
17Nephronophthisis (HP:0000090)4.06388922
18Abnormal rod and cone electroretinograms (HP:0008323)3.98214287
19Hyperkalemia (HP:0002153)3.90645797
20Resting tremor (HP:0002322)3.73491014
21Abnormality of macular pigmentation (HP:0008002)3.63412177
22Chronic hepatic failure (HP:0100626)3.60459618
23Recurrent otitis media (HP:0000403)3.56377724
24Hypoplastic ischia (HP:0003175)3.55424715
25Recurrent bronchitis (HP:0002837)3.31275991
26Potter facies (HP:0002009)3.29674031
27Facial shape deformation (HP:0011334)3.29674031
28Abnormality of the parathyroid morphology (HP:0011766)3.26091610
29Abnormal spermatogenesis (HP:0008669)3.25993778
30Recurrent sinusitis (HP:0011108)3.24688156
31Hypoalphalipoproteinemia (HP:0003233)3.16825564
32Abnormality of the ischium (HP:0003174)3.15056519
33Focal motor seizures (HP:0011153)3.10236053
34Impulsivity (HP:0100710)3.06253569
35Progressive sensorineural hearing impairment (HP:0000408)3.00262264
36Abnormality of the renal medulla (HP:0100957)2.95051740
37Hypoplasia of the thymus (HP:0000778)2.88885374
38Enlarged epiphyses (HP:0010580)2.87508727
39Aplasia/Hypoplasia of the earlobes (HP:0009906)2.83820917
40Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.65830341
41Tubulointerstitial nephritis (HP:0001970)2.57037547
42Cholecystitis (HP:0001082)2.53943126
43Abnormal gallbladder physiology (HP:0012438)2.53943126
44Cone-rod dystrophy (HP:0000548)2.49901279
45Spastic tetraparesis (HP:0001285)2.48413246
46Choroideremia (HP:0001139)2.44321456
47Abnormality of the aortic arch (HP:0012303)2.43838407
48Hypolipoproteinemia (HP:0010981)2.43544997
49Down-sloping shoulders (HP:0200021)2.42267103
50Heterotopia (HP:0002282)2.39519386
51Tubular atrophy (HP:0000092)2.38682745
52Gonadotropin excess (HP:0000837)2.37472088
53Anterior segment dysgenesis (HP:0007700)2.34460661
54Molar tooth sign on MRI (HP:0002419)2.33975521
55Abnormality of midbrain morphology (HP:0002418)2.33975521
56Generalized aminoaciduria (HP:0002909)2.32202494
57Unilateral renal agenesis (HP:0000122)2.31384011
58Mixed hearing impairment (HP:0000410)2.28965140
59Dyschromatopsia (HP:0007641)2.22755651
60Atelectasis (HP:0100750)2.20933529
61Abnormality of dental color (HP:0011073)2.20887470
62Medial flaring of the eyebrow (HP:0010747)2.19677756
63Peripheral hypomyelination (HP:0007182)2.19038193
64Tubulointerstitial abnormality (HP:0001969)2.17349396
65Hyperthyroidism (HP:0000836)2.15046186
66Bulbous nose (HP:0000414)2.13065914
67Insulin-resistant diabetes mellitus (HP:0000831)2.10242476
68Recurrent pneumonia (HP:0006532)2.09965034
69Decreased central vision (HP:0007663)2.08991417
70Portal hypertension (HP:0001409)2.08298260
71Esophageal atresia (HP:0002032)2.05565321
72Oligodactyly (hands) (HP:0001180)2.03932643
73Acanthosis nigricans (HP:0000956)2.02996981
74Hypoplasia of the capital femoral epiphysis (HP:0003090)2.02579753
75Abnormality of potassium homeostasis (HP:0011042)2.01156654
76Absent/shortened dynein arms (HP:0200106)12.6084512
77Dynein arm defect of respiratory motile cilia (HP:0012255)12.6084512
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.3889044
79Abnormality of the costochondral junction (HP:0000919)1.98982245
80Abnormality of the lower motor neuron (HP:0002366)1.96170085
81Hemiparesis (HP:0001269)1.93513644
82Tetany (HP:0001281)1.92273591
83Abnormality of the hepatic vasculature (HP:0006707)1.92153822
84Postural instability (HP:0002172)1.91358147
85Pigmentary retinal degeneration (HP:0001146)1.89585524
86Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.86175683
87Azoospermia (HP:0000027)1.86048730
88Neurofibrillary tangles (HP:0002185)1.85720236
89Subcapsular cataract (HP:0000523)1.84334938
90Occipital encephalocele (HP:0002085)1.84121141
91Epiphyseal dysplasia (HP:0002656)1.83783136
92Omphalocele (HP:0001539)1.82526340
93Progressive hearing impairment (HP:0001730)1.82219805
94Hypertriglyceridemia (HP:0002155)1.82106895
95Protuberant abdomen (HP:0001538)1.80993956
96Polyuria (HP:0000103)1.77137249
97Recurrent corneal erosions (HP:0000495)1.76857697
98Chronic sinusitis (HP:0011109)1.76485760
99Bradycardia (HP:0001662)1.76035968
100Intestinal atresia (HP:0011100)1.73024969
101Pendular nystagmus (HP:0012043)1.72487948
102Widely patent fontanelles and sutures (HP:0004492)1.71943492
103Horizontal nystagmus (HP:0000666)1.71367542
104Abnormality of ocular smooth pursuit (HP:0000617)1.70633497
105Tubulointerstitial fibrosis (HP:0005576)1.70378374
106Poikilocytosis (HP:0004447)1.70337570
107Stage 5 chronic kidney disease (HP:0003774)1.68713471
108Dysmetric saccades (HP:0000641)1.68097148
109Hemorrhage of the eye (HP:0011885)1.66471772
110Myokymia (HP:0002411)1.65611712
111Cerebral inclusion bodies (HP:0100314)1.64622157
112Atrophic scars (HP:0001075)1.64226275
113Amyotrophic lateral sclerosis (HP:0007354)1.64176337
114Amblyopia (HP:0000646)1.63915556
115Decreased electroretinogram (ERG) amplitude (HP:0000654)1.63568605
116Cerebellar dysplasia (HP:0007033)1.63066132
117Polydipsia (HP:0001959)1.62022650
118Abnormal drinking behavior (HP:0030082)1.62022650
119Bundle branch block (HP:0011710)1.58644715
120Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.57817728
121Absent epiphyses (HP:0010577)1.57817728
122Impaired smooth pursuit (HP:0007772)1.56323292
123Postaxial foot polydactyly (HP:0001830)1.55598738
124Short ribs (HP:0000773)1.54282308
125Aplasia/Hypoplasia of the lens (HP:0008063)1.53101833
126Bell-shaped thorax (HP:0001591)1.51945303
127Abnormality of saccadic eye movements (HP:0000570)1.49288763
128Loss of speech (HP:0002371)1.48516053
129Exercise-induced myalgia (HP:0003738)1.46242695
130Neoplasm of the heart (HP:0100544)1.43962542
131Truncal obesity (HP:0001956)1.43514431
132Easy fatigability (HP:0003388)1.41470604
133Oculomotor apraxia (HP:0000657)1.40896616
134Abnormality of renal excretion (HP:0011036)1.38820071
135Congenital hepatic fibrosis (HP:0002612)1.38691781
136Deformed sella turcica (HP:0002681)1.38511679
137Difficulty climbing stairs (HP:0003551)1.38188929
138Absent frontal sinuses (HP:0002688)1.37788541
139Renovascular hypertension (HP:0100817)1.37053014
140Renal dysplasia (HP:0000110)1.36981830
141Progressive cerebellar ataxia (HP:0002073)1.36892892
142Type II lissencephaly (HP:0007260)1.36275795
143Postaxial hand polydactyly (HP:0001162)1.34871876
144Lissencephaly (HP:0001339)1.34016733
145Gait imbalance (HP:0002141)1.30435462
146Retinal dysplasia (HP:0007973)1.30347158
147Broad distal phalanx of finger (HP:0009836)1.29652540
148Neuronal loss in central nervous system (HP:0002529)1.26982134
149Polymicrogyria (HP:0002126)1.26959049
150Congenital malformation of the right heart (HP:0011723)1.26438510
151Double outlet right ventricle (HP:0001719)1.26438510
152Impaired vibration sensation in the lower limbs (HP:0002166)1.26051584
153Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.25093816
154Congenital primary aphakia (HP:0007707)1.24233365
155EMG: neuropathic changes (HP:0003445)1.23959346
156Supranuclear gaze palsy (HP:0000605)1.22873550
157Abnormal biliary tract physiology (HP:0012439)1.22428093
158Bile duct proliferation (HP:0001408)1.22428093
159Asymmetric septal hypertrophy (HP:0001670)1.21942299
160Pachygyria (HP:0001302)1.21582643
161Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.21032223
162Abnormal urine output (HP:0012590)1.20767874
163Sensory axonal neuropathy (HP:0003390)1.18469495
164Abnormality of the neuromuscular junction (HP:0003398)1.18371418
165Fatigable weakness (HP:0003473)1.18371418

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK17.07174858
2PDK46.88635347
3PDK36.88635347
4PRKD36.53972856
5PLK45.98223586
6ICK5.21309923
7DDR24.72293242
8PDK24.26109431
9MAP4K23.05822602
10INSRR2.39476551
11PIK3CG2.39459915
12AKT32.38338150
13BRD42.37719988
14STK382.35726293
15PLK22.22877360
16PTK2B2.13487471
17NEK21.97505501
18PNCK1.78091316
19WNK41.72485216
20DYRK1B1.70476004
21BLK1.62188667
22STK391.58511620
23STK38L1.55972165
24UHMK11.38721663
25MAP3K111.34841835
26PDK11.27436587
27EEF2K1.27181906
28TYRO31.20023004
29MST1R1.13534746
30SGK2231.04792122
31SGK4941.04792122
32ADRBK21.03732614
33CAMK1D1.03726897
34LATS21.01790158
35BRAF0.94872369
36KSR20.94472824
37WNK10.92130629
38RPS6KA20.87855917
39MAP2K10.84833638
40RIPK40.84798268
41CDK70.84413267
42MAP3K80.83165760
43PDPK10.82234529
44CAMK1G0.82221426
45TESK20.81874809
46MET0.79476150
47NTRK20.79314816
48GRK10.77940253
49ROCK10.77582454
50CAMK40.77571320
51PASK0.76675301
52PRKAA20.76284425
53PRKG20.73675589
54MST40.72250734
55ACVR1B0.71103286
56DYRK20.70705867
57CAMKK10.70211483
58NTRK30.69176174
59MAP3K100.68526072
60DYRK30.66432869
61MAP2K20.66093457
62CHEK20.65399613
63MARK20.64539048
64MAP3K20.64083515
65MYLK0.57633399
66SGK20.56461029
67CASK0.55959183
68CCNB10.55126680
69TRIB30.54344723
70MAP3K10.53894995
71RPS6KL10.53035551
72RPS6KC10.53035551
73FRK0.52184867
74RPS6KA60.51701524
75STK30.51233830
76TIE10.50478270
77IRAK10.48484892
78PAK60.48419861
79EPHB20.46798042
80MAPK130.44433032
81IRAK20.43544238
82MTOR0.43508225
83SGK10.43139994
84NME10.42931146
85MAP2K70.42621253
86CHUK0.42518998
87MAPK10.42307959
88PAK10.42276715
89CHEK10.42052292
90ABL20.42000390
91MAP2K60.41766839
92LMTK20.40657047
93MAPK150.40353638
94CDK120.40333304
95NEK90.38594614
96TTK0.38452890
97PRKCG0.37043960
98TLK10.36547238
99PAK20.35537461
100ADRBK10.33631144
101SGK30.33284471
102MAPKAPK30.33261890
103RIPK10.32236342
104PINK10.28759491
105PAK40.28487457
106ATM0.28324944
107MAPK140.28247141
108MINK10.27926615
109HIPK20.27817183
110MAPK110.27092014
111BRSK10.26395228
112MARK10.25343256
113EPHA20.24898710
114BMX0.24246533
115ATR0.23908598
116CDK150.23881032
117SIK20.23067976
118PRKAA10.22855721
119PKN20.21268463
120TAOK10.21179368
121PRKCZ0.21089212
122MUSK0.20361112
123RPS6KB10.20162302
124CDK180.19855927
125CDC70.19613314
126CDK11A0.18907080
127PTK60.18742567
128MARK30.18246019
129STK110.17147487
130MAP4K10.16191859
131CDK140.16039859
132MAP3K40.15967524
133PKN10.13948060
134RPS6KA10.13703586
135CDK60.13626262
136PRKCQ0.13374459
137GSK3B0.12731149
138ZAP700.12628603
139MAP3K90.11113889
140MAPK80.10562902
141CAMK10.10403904
142CDK20.10333841
143CSNK1D0.09638057
144STK100.08754588
145CSF1R0.08680864
146RPS6KA30.07837253
147PRKCB0.07127261
148FES0.06625874
149NEK60.06249352
150EGFR0.06165708
151CDK50.06045078
152PDGFRB0.05727444
153PRKG10.05222206
154PRKDC0.05085070
155ERN10.04882634
156CDK10.04812467
157MAPKAPK50.04393024
158PRKACG0.04153386
159YES10.03455403
160TTN0.03285598
161EPHB10.03140970
162PLK10.02892254
163MAPK100.02239591

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000726.50419467
2Fatty acid biosynthesis_Homo sapiens_hsa000614.25970505
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.88750690
4Vitamin B6 metabolism_Homo sapiens_hsa007502.82746468
5Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.73779053
6Carbohydrate digestion and absorption_Homo sapiens_hsa049732.65016025
7Pyruvate metabolism_Homo sapiens_hsa006202.57980971
8Glucagon signaling pathway_Homo sapiens_hsa049222.55751910
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.42519797
10Linoleic acid metabolism_Homo sapiens_hsa005912.29192667
11Phenylalanine metabolism_Homo sapiens_hsa003602.19186453
12Amphetamine addiction_Homo sapiens_hsa050312.13448752
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.11179906
14Dorso-ventral axis formation_Homo sapiens_hsa043202.07911594
15Butanoate metabolism_Homo sapiens_hsa006501.98154629
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.98100183
17Oocyte meiosis_Homo sapiens_hsa041141.94885137
18Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.91448481
19Tyrosine metabolism_Homo sapiens_hsa003501.91400941
20Glycerolipid metabolism_Homo sapiens_hsa005611.82623020
21Long-term potentiation_Homo sapiens_hsa047201.73000183
22Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.67122721
23Glycerophospholipid metabolism_Homo sapiens_hsa005641.56134213
24Selenocompound metabolism_Homo sapiens_hsa004501.55601101
25Basal transcription factors_Homo sapiens_hsa030221.55547881
26Propanoate metabolism_Homo sapiens_hsa006401.54005949
27Fructose and mannose metabolism_Homo sapiens_hsa000511.53845908
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.51284658
29Renin secretion_Homo sapiens_hsa049241.46754664
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.39263753
31Synaptic vesicle cycle_Homo sapiens_hsa047211.37648329
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37628690
33PPAR signaling pathway_Homo sapiens_hsa033201.33862869
34Allograft rejection_Homo sapiens_hsa053301.32196894
35Insulin secretion_Homo sapiens_hsa049111.28295093
36Autoimmune thyroid disease_Homo sapiens_hsa053201.27815903
37Cardiac muscle contraction_Homo sapiens_hsa042601.25452414
38Pentose phosphate pathway_Homo sapiens_hsa000301.21888149
39Phototransduction_Homo sapiens_hsa047441.20137148
40mRNA surveillance pathway_Homo sapiens_hsa030151.16776369
41Estrogen signaling pathway_Homo sapiens_hsa049151.16452652
42Sulfur relay system_Homo sapiens_hsa041221.07907181
43Salivary secretion_Homo sapiens_hsa049701.07549098
44Mineral absorption_Homo sapiens_hsa049781.06999583
45ECM-receptor interaction_Homo sapiens_hsa045121.06830647
46Hedgehog signaling pathway_Homo sapiens_hsa043401.06827740
47Graft-versus-host disease_Homo sapiens_hsa053321.06140659
48Antigen processing and presentation_Homo sapiens_hsa046121.05815235
49Circadian entrainment_Homo sapiens_hsa047131.05440863
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.02876799
51Nicotine addiction_Homo sapiens_hsa050331.01129298
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.00407061
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99057136
54Type I diabetes mellitus_Homo sapiens_hsa049400.98937511
55Fanconi anemia pathway_Homo sapiens_hsa034600.98615373
56Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95834587
57Ether lipid metabolism_Homo sapiens_hsa005650.95344772
58Arginine biosynthesis_Homo sapiens_hsa002200.94006883
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.93452199
60Thyroid hormone synthesis_Homo sapiens_hsa049180.92082232
61Fat digestion and absorption_Homo sapiens_hsa049750.91869441
62Carbon metabolism_Homo sapiens_hsa012000.90680361
63Collecting duct acid secretion_Homo sapiens_hsa049660.90573292
64Adipocytokine signaling pathway_Homo sapiens_hsa049200.90285885
65Gastric acid secretion_Homo sapiens_hsa049710.89579126
66Taste transduction_Homo sapiens_hsa047420.89019271
67Fatty acid metabolism_Homo sapiens_hsa012120.88679360
68Calcium signaling pathway_Homo sapiens_hsa040200.88248510
69Glutamatergic synapse_Homo sapiens_hsa047240.88118813
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.87793570
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.85009549
72VEGF signaling pathway_Homo sapiens_hsa043700.80852495
73Inositol phosphate metabolism_Homo sapiens_hsa005620.79669647
74Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.79393048
75Nitrogen metabolism_Homo sapiens_hsa009100.78938558
76Viral myocarditis_Homo sapiens_hsa054160.78250864
77RNA transport_Homo sapiens_hsa030130.77635838
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75436875
79cAMP signaling pathway_Homo sapiens_hsa040240.75008667
80Aldosterone synthesis and secretion_Homo sapiens_hsa049250.74937863
81Alcoholism_Homo sapiens_hsa050340.74699299
82Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72810704
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72217639
84GABAergic synapse_Homo sapiens_hsa047270.71659961
85B cell receptor signaling pathway_Homo sapiens_hsa046620.71102301
86Arginine and proline metabolism_Homo sapiens_hsa003300.70798285
87Galactose metabolism_Homo sapiens_hsa000520.70224442
88Systemic lupus erythematosus_Homo sapiens_hsa053220.68646565
89Cocaine addiction_Homo sapiens_hsa050300.68421484
90Pancreatic secretion_Homo sapiens_hsa049720.68296974
91Endocytosis_Homo sapiens_hsa041440.68271034
92Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68188691
93Fatty acid degradation_Homo sapiens_hsa000710.67931276
94Bile secretion_Homo sapiens_hsa049760.67605216
95Vascular smooth muscle contraction_Homo sapiens_hsa042700.67319598
96Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67211523
97Cholinergic synapse_Homo sapiens_hsa047250.65738690
98Serotonergic synapse_Homo sapiens_hsa047260.65725659
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.65342022
100Dopaminergic synapse_Homo sapiens_hsa047280.64648437
101Biosynthesis of amino acids_Homo sapiens_hsa012300.61747588
102Type II diabetes mellitus_Homo sapiens_hsa049300.61590299
103AMPK signaling pathway_Homo sapiens_hsa041520.60420192
104Olfactory transduction_Homo sapiens_hsa047400.60269626
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58998310
106MAPK signaling pathway_Homo sapiens_hsa040100.57964295
107Influenza A_Homo sapiens_hsa051640.57821970
108Purine metabolism_Homo sapiens_hsa002300.57630099
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.57386274
110Retinol metabolism_Homo sapiens_hsa008300.54311896
111Oxytocin signaling pathway_Homo sapiens_hsa049210.53419701
112Morphine addiction_Homo sapiens_hsa050320.52360831
113Tight junction_Homo sapiens_hsa045300.50017616
114Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49956126
115Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49094238
116Peroxisome_Homo sapiens_hsa041460.48373974
117Chemical carcinogenesis_Homo sapiens_hsa052040.46742964
118T cell receptor signaling pathway_Homo sapiens_hsa046600.44639770
119Maturity onset diabetes of the young_Homo sapiens_hsa049500.43521712
120Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.41054413
121Legionellosis_Homo sapiens_hsa051340.37671642
122ABC transporters_Homo sapiens_hsa020100.36606788
123Huntingtons disease_Homo sapiens_hsa050160.36405777
124Tryptophan metabolism_Homo sapiens_hsa003800.36129302
125N-Glycan biosynthesis_Homo sapiens_hsa005100.33987183
126Longevity regulating pathway - mammal_Homo sapiens_hsa042110.32930473
127Regulation of autophagy_Homo sapiens_hsa041400.32790729
128Wnt signaling pathway_Homo sapiens_hsa043100.32288467
129Renin-angiotensin system_Homo sapiens_hsa046140.31907210
130Acute myeloid leukemia_Homo sapiens_hsa052210.29797148
131HIF-1 signaling pathway_Homo sapiens_hsa040660.29576729
132Focal adhesion_Homo sapiens_hsa045100.28889739
133Viral carcinogenesis_Homo sapiens_hsa052030.28425738
134Glutathione metabolism_Homo sapiens_hsa004800.27922036
135Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.27725356
136Basal cell carcinoma_Homo sapiens_hsa052170.27690431
137Jak-STAT signaling pathway_Homo sapiens_hsa046300.25870990
138Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.25430529
139Protein digestion and absorption_Homo sapiens_hsa049740.25170079
140FoxO signaling pathway_Homo sapiens_hsa040680.24830116
141Vitamin digestion and absorption_Homo sapiens_hsa049770.23293264

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »