ANKRD66

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1left/right pattern formation (GO:0060972)9.44038488
2cilium movement (GO:0003341)8.44092867
3regulation of cilium movement (GO:0003352)7.57239425
4GTP biosynthetic process (GO:0006183)7.38647329
5intraciliary transport (GO:0042073)7.18037431
6axoneme assembly (GO:0035082)7.04275272
7primary alcohol catabolic process (GO:0034310)6.60767089
8UTP biosynthetic process (GO:0006228)6.54605139
9nucleoside diphosphate phosphorylation (GO:0006165)6.53535414
10axonemal dynein complex assembly (GO:0070286)6.53285933
11cilium organization (GO:0044782)6.36028264
12microtubule bundle formation (GO:0001578)6.24921666
13cilium assembly (GO:0042384)6.12325599
14UTP metabolic process (GO:0046051)6.06620738
15vitamin transmembrane transport (GO:0035461)5.73756890
16left/right axis specification (GO:0070986)5.71792826
17regulation of mononuclear cell migration (GO:0071675)5.56537827
18ventricular system development (GO:0021591)5.55736458
19centriole assembly (GO:0098534)5.46883131
20ethanol metabolic process (GO:0006067)5.45124461
21protein localization to cilium (GO:0061512)5.29966537
22diterpenoid biosynthetic process (GO:0016102)5.20541174
23cilium or flagellum-dependent cell motility (GO:0001539)5.14107406
24microtubule-based movement (GO:0007018)5.13537923
25epithelial cilium movement (GO:0003351)5.03045411
26cellular component assembly involved in morphogenesis (GO:0010927)4.91021219
27cilium morphogenesis (GO:0060271)4.90823403
28CTP biosynthetic process (GO:0006241)4.80901632
29CTP metabolic process (GO:0046036)4.80901632
30pyrimidine-containing compound transmembrane transport (GO:0072531)4.72595910
31tolerance induction (GO:0002507)4.66727191
32sperm capacitation (GO:0048240)4.63887143
33T-helper 1 type immune response (GO:0042088)4.58268417
34cellular response to interferon-alpha (GO:0035457)4.51313978
35response to xenobiotic stimulus (GO:0009410)4.49639874
36guanosine-containing compound biosynthetic process (GO:1901070)4.47343326
37negative regulation of T cell differentiation in thymus (GO:0033085)4.43066871
38regulation of microtubule-based movement (GO:0060632)4.41670936
39cell projection assembly (GO:0030031)4.41056404
40pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.36453739
41one-carbon compound transport (GO:0019755)4.33940785
42lung epithelium development (GO:0060428)4.33924291
43modulation by symbiont of host immune response (GO:0052553)4.29812473
44positive regulation by symbiont of host defense response (GO:0052509)4.29812473
45modulation by symbiont of host defense response (GO:0052031)4.29812473
46modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.29812473
47modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.29812473
48positive regulation by organism of defense response of other organism involved in symbiotic interact4.29812473
49neutrophil activation involved in immune response (GO:0002283)4.28936629
50establishment of apical/basal cell polarity (GO:0035089)4.20340376
51glomerular epithelial cell development (GO:0072310)4.19257173
52regulation of RIG-I signaling pathway (GO:0039535)4.17470681
53ethanol oxidation (GO:0006069)4.17240963
54antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.15305177
55regulation of interleukin-5 production (GO:0032674)4.14185794
56pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.14099901
57regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)4.06625413
58respiratory burst (GO:0045730)4.04891379
59positive regulation of monocyte chemotaxis (GO:0090026)4.02293253
60response to peptidoglycan (GO:0032494)3.99485379
61negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.97874132
62eosinophil chemotaxis (GO:0048245)3.95120618
63cellular response to zinc ion (GO:0071294)3.95052144
64negative regulation of immunoglobulin mediated immune response (GO:0002890)3.94853931
65negative regulation of B cell mediated immunity (GO:0002713)3.94853931
66lateral ventricle development (GO:0021670)3.94465817
67positive regulation of tolerance induction (GO:0002645)3.85996920
68regulation of macrophage chemotaxis (GO:0010758)3.85648028
69negative regulation of humoral immune response (GO:0002921)3.83607400
70type I interferon signaling pathway (GO:0060337)3.81239006
71cellular response to type I interferon (GO:0071357)3.81239006
72centriole replication (GO:0007099)3.79101482
73regulation of chemokine biosynthetic process (GO:0045073)3.78817412
74response to type I interferon (GO:0034340)3.78621513
75microglial cell activation (GO:0001774)3.76928952
76retinoic acid metabolic process (GO:0042573)3.73458321
77regulation of activation of Janus kinase activity (GO:0010533)3.72727596
78cellular response to exogenous dsRNA (GO:0071360)3.71960772
79hydrogen peroxide biosynthetic process (GO:0050665)3.70624539
80positive regulation of chemokine biosynthetic process (GO:0045080)3.70547730
81positive regulation of interferon-alpha production (GO:0032727)3.70260201
82regulation of germinal center formation (GO:0002634)3.67912295
83establishment or maintenance of monopolar cell polarity (GO:0061339)3.66992405
84establishment of monopolar cell polarity (GO:0061162)3.66992405
85regulation of interleukin-13 production (GO:0032656)3.66199831
86terpenoid biosynthetic process (GO:0016114)3.62596233
87regulation of T-helper 1 cell differentiation (GO:0045625)3.62178418
88determination of left/right symmetry (GO:0007368)3.60910604
89lipopolysaccharide-mediated signaling pathway (GO:0031663)3.60744078
90positive regulation of type 2 immune response (GO:0002830)3.58659324
91cytoplasmic microtubule organization (GO:0031122)3.58252792
92eosinophil migration (GO:0072677)3.56236451
93positive regulation of T-helper cell differentiation (GO:0045624)3.54601400
94response to interferon-alpha (GO:0035455)3.54272946
95positive regulation of toll-like receptor signaling pathway (GO:0034123)3.53744161
96nucleotide phosphorylation (GO:0046939)3.51914676
97glutathione derivative metabolic process (GO:1901685)3.51112362
98glutathione derivative biosynthetic process (GO:1901687)3.51112362
99positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.49664630
100regulation of interferon-alpha production (GO:0032647)3.47906037
101determination of bilateral symmetry (GO:0009855)3.45702665
102natural killer cell mediated immunity (GO:0002228)3.45133576
103natural killer cell mediated cytotoxicity (GO:0042267)3.45133576
104lymphocyte chemotaxis (GO:0048247)3.44108924
105granulocyte activation (GO:0036230)3.43340315
106regulation of T-helper 2 cell differentiation (GO:0045628)3.43291699
107specification of symmetry (GO:0009799)3.40574689
108monocyte chemotaxis (GO:0002548)3.40039888
109microtubule depolymerization (GO:0007019)3.39315744
110pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.38277197
111superoxide anion generation (GO:0042554)3.35170163
112defense response to protozoan (GO:0042832)3.33691582
113positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.29818227
114epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.28098199
115retinol metabolic process (GO:0042572)3.23011263
116reactive oxygen species biosynthetic process (GO:1903409)3.21589655
117negative regulation of viral genome replication (GO:0045071)3.21410784
118smoothened signaling pathway (GO:0007224)3.17290131
119positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.16895106
120sperm motility (GO:0030317)3.15175098
121regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.13919990
122regulation of monocyte chemotaxis (GO:0090025)3.13562021
123microtubule polymerization or depolymerization (GO:0031109)3.13540951
124exogenous drug catabolic process (GO:0042738)3.12982457
125establishment of tissue polarity (GO:0007164)3.11002310
126establishment of planar polarity (GO:0001736)3.11002310
127cellular response to interferon-beta (GO:0035458)3.10707349
128primary alcohol metabolic process (GO:0034308)3.09711816
129positive regulation of lymphocyte migration (GO:2000403)3.05736929
130regulation of interferon-gamma biosynthetic process (GO:0045072)3.02045081
131wound healing, spreading of epidermal cells (GO:0035313)3.01536512
132macrophage activation involved in immune response (GO:0002281)2.99369839
133regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.99305664
134motile cilium assembly (GO:0044458)2.97275650
135negative regulation of inclusion body assembly (GO:0090084)2.96116536
136regulation of T-helper cell differentiation (GO:0045622)2.94692661
137regulation of autophagic vacuole assembly (GO:2000785)2.93140036
138positive regulation of interleukin-12 production (GO:0032735)2.91880725
139regulation of immunoglobulin secretion (GO:0051023)2.90862606
140positive regulation of smoothened signaling pathway (GO:0045880)2.90382257
141immunoglobulin mediated immune response (GO:0016064)2.89931598
142regulation of tolerance induction (GO:0002643)2.89698524
143pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.89426681
144neutrophil activation (GO:0042119)2.89190455
145microtubule-based process (GO:0007017)2.89183237
146O-glycan processing (GO:0016266)2.85043784
147response to protozoan (GO:0001562)2.83525186
148nucleoside diphosphate metabolic process (GO:0009132)2.83484510
149apical protein localization (GO:0045176)2.83094401
150negative regulation of interleukin-17 production (GO:0032700)2.82903397
151positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.80775735
152positive regulation of mast cell activation involved in immune response (GO:0033008)2.77374433
153positive regulation of mast cell degranulation (GO:0043306)2.77374433
154positive regulation of heat generation (GO:0031652)2.76139532
155response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.74308908
156response to host immune response (GO:0052572)2.74308908
157organelle assembly (GO:0070925)2.74186499
158positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.73999257
159response to interferon-beta (GO:0035456)2.73947185
160positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.73647369
161positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.73460741
162positive regulation of natural killer cell differentiation (GO:0032825)2.73392079
163leukocyte mediated cytotoxicity (GO:0001909)2.72714127
164positive regulation of response to biotic stimulus (GO:0002833)2.71031522
165ADP metabolic process (GO:0046031)2.69153085
166lateral sprouting from an epithelium (GO:0060601)2.65731656
167phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.57808758
168regulation of vacuole organization (GO:0044088)2.57504184
169regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.57045983
170CDP-diacylglycerol biosynthetic process (GO:0016024)2.48665246
171aldehyde catabolic process (GO:0046185)2.48009270
172regulation of microtubule depolymerization (GO:0031114)2.44072470
173multicellular organismal water homeostasis (GO:0050891)2.43230221
174heart looping (GO:0001947)2.42002320
175drug catabolic process (GO:0042737)2.39688829
176carnitine metabolic process (GO:0009437)2.38727120
177phosphatidylcholine biosynthetic process (GO:0006656)2.37270193
178excretion (GO:0007588)2.37192921
179regulation of collateral sprouting (GO:0048670)2.34559927
180glutathione metabolic process (GO:0006749)2.34212153
181progesterone metabolic process (GO:0042448)2.33933863
182retinal rod cell development (GO:0046548)2.31702815
183phenol-containing compound catabolic process (GO:0019336)2.28730960
184asymmetric protein localization (GO:0008105)2.27252151

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.52297554
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.39911511
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.97697305
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.76427195
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.57447272
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.78370049
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.37663714
8DROSHA_22980978_ChIP-Seq_HELA_Human3.34584276
9FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.13849942
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.84516962
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.83899177
12Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.81142647
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.67421300
14TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.66098681
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.38300082
16RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.37791678
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.36179445
18GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.35145502
19STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.20854164
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.20109202
21CDX2_19796622_ChIP-Seq_MESCs_Mouse2.17277767
22STAT1_20625510_ChIP-Seq_HELA_Human2.03076242
23STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.90495557
24AHR_22903824_ChIP-Seq_MCF-7_Human1.89418856
25ESR1_20079471_ChIP-ChIP_T-47D_Human1.88292136
26RUNX1_27514584_Chip-Seq_MCF-7_Human1.78795710
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.76358979
28VDR_22108803_ChIP-Seq_LS180_Human1.75451608
29NR3C1_21868756_ChIP-Seq_MCF10A_Human1.71556055
30CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.69915401
31TRIM28_21343339_ChIP-Seq_HEK293_Human1.68763311
32EGR1_19374776_ChIP-ChIP_THP-1_Human1.68032913
33CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.66641193
34SOX2_27498859_Chip-Seq_STOMACH_Mouse1.65547629
35FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.65231041
36STAT4_19710469_ChIP-ChIP_TH1__Mouse1.62412527
37ARNT_22903824_ChIP-Seq_MCF-7_Human1.60254138
38CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.56894678
39SMC4_20622854_ChIP-Seq_HELA_Human1.56613136
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.56539492
41STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.56398298
42ESR2_21235772_ChIP-Seq_MCF-7_Human1.54825797
43SMAD_19615063_ChIP-ChIP_OVARY_Human1.53510133
44CTNNB1_20460455_ChIP-Seq_HCT116_Human1.53233952
45ESR1_21235772_ChIP-Seq_MCF-7_Human1.43331338
46ETV1_20927104_ChIP-Seq_GIST48_Human1.39483702
47AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.38882319
48AR_21572438_ChIP-Seq_LNCaP_Human1.37161671
49TP63_22573176_ChIP-Seq_HFKS_Human1.36261747
50VDR_24787735_ChIP-Seq_THP-1_Human1.36099009
51SOX9_24532713_ChIP-Seq_HFSC_Mouse1.35080386
52RAD21_21589869_ChIP-Seq_MESCs_Mouse1.34546198
53KLF5_25053715_ChIP-Seq_YYC3_Human1.34343774
54PHF8_20622853_ChIP-Seq_HELA_Human1.32837139
55MYB_21317192_ChIP-Seq_ERMYB_Mouse1.32615314
56STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.32259607
57FOXA1_25552417_ChIP-Seq_VCAP_Human1.31408702
58ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.31202541
59NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.29783133
60NRF2_20460467_ChIP-Seq_MEFs_Mouse1.29783133
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29608667
62CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.29243301
63PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.28928948
64PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27632391
65HNFA_21074721_ChIP-Seq_CACO-2_Human1.26750726
66SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.25770294
67CJUN_26792858_Chip-Seq_BT549_Human1.25213201
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.24320460
69PU_27001747_Chip-Seq_BMDM_Mouse1.24070612
70SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.23925081
71ELF1_20517297_ChIP-Seq_JURKAT_Human1.23394118
72P63_26484246_Chip-Seq_KERATINOCYTES_Human1.22667530
73IKZF1_21737484_ChIP-ChIP_HCT116_Human1.22664127
74NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.21421426
75CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19770899
76CDX2_20551321_ChIP-Seq_CACO-2_Human1.19009742
77GATA1_19941826_ChIP-Seq_K562_Human1.18141174
78MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.17489821
79TDRD3_21172665_ChIP-Seq_MCF-7_Human1.17170810
80SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.16187634
81CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.14371144
82ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.13670615
83RBPJ_21746931_ChIP-Seq_IB4_Human1.12578900
84NFYA_21822215_ChIP-Seq_K562_Human1.12299208
85BCAT_22108803_ChIP-Seq_LS180_Human1.11486929
86ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.11318632
87BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.10707411
88P300_19829295_ChIP-Seq_ESCs_Human1.09572200
89TBL1_22424771_ChIP-Seq_293T_Human1.08476156
90GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.06008774
91NFYB_21822215_ChIP-Seq_K562_Human1.05623853
92GATA6_21074721_ChIP-Seq_CACO-2_Human1.05236618
93SMAD4_21799915_ChIP-Seq_A2780_Human1.05228765
94CTCF_20526341_ChIP-Seq_ESCs_Human1.04218999
95CBX2_22325352_ChIP-Seq_293T-Rex_Human1.04132973
96CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03010482
97ZFP57_27257070_Chip-Seq_ESCs_Mouse1.02605699
98FLI1_27457419_Chip-Seq_LIVER_Mouse1.02457028
99CEBPB_22108803_ChIP-Seq_LS180_Human1.02058209
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.01907887
101SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01668062
102MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.01410372
103GATA4_25053715_ChIP-Seq_YYC3_Human1.00739518
104YY1_22570637_ChIP-Seq_MALME-3M_Human1.00422986
105PIAS1_25552417_ChIP-Seq_VCAP_Human0.99929718
106POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99875789
107POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99455353
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99455353
109CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99007894
110SOX2_20726797_ChIP-Seq_SW620_Human0.98237104
111CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98203067
112FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.98127194
113CTCF_27219007_Chip-Seq_Bcells_Human0.97896440
114CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97669490
115WDR5_24793694_ChIP-Seq_LNCAP_Human0.97646469
116TCF4_22108803_ChIP-Seq_LS180_Human0.97017600
117SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.96723811
118TP53_18474530_ChIP-ChIP_U2OS_Human0.96500411
119ER_23166858_ChIP-Seq_MCF-7_Human0.96469057
120TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95604751
121TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95387149
122P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95244302
123GATA3_24758297_ChIP-Seq_MCF-7_Human0.94839892
124PPAR_26484153_Chip-Seq_NCI-H1993_Human0.94263246
125SMAD3_21741376_ChIP-Seq_HESCs_Human0.93330410
126PHF8_20622854_ChIP-Seq_HELA_Human0.93056168
127ERG_20517297_ChIP-Seq_VCAP_Human0.92878854
128FOXA1_25329375_ChIP-Seq_VCAP_Human0.92765216
129FOXA1_27270436_Chip-Seq_PROSTATE_Human0.92765216
130CTBP2_25329375_ChIP-Seq_LNCAP_Human0.92387880
131EZH2_27294783_Chip-Seq_ESCs_Mouse0.92322258
132RXR_22108803_ChIP-Seq_LS180_Human0.91176451
133GATA3_27048872_Chip-Seq_THYMUS_Human0.90990888
134PU1_27457419_Chip-Seq_LIVER_Mouse0.90924656
135PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90770574
136GATA3_26560356_Chip-Seq_TH2_Human0.90425721
137STAT3_23295773_ChIP-Seq_U87_Human0.89968418
138SOX2_21211035_ChIP-Seq_LN229_Human0.89956518
139P68_20966046_ChIP-Seq_HELA_Human0.89621790
140SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.89466318
141EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.89438691
142GATA1_26923725_Chip-Seq_HPCs_Mouse0.88798938
143FOXA2_19822575_ChIP-Seq_HepG2_Human0.88787056
144TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88668172
145P300_27268052_Chip-Seq_Bcells_Human0.88505889
146KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.87946478
147FOXO3_23340844_ChIP-Seq_DLD1_Human0.87168794
148FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.86608493
149FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85087153
150NFE2_27457419_Chip-Seq_LIVER_Mouse0.84518304
151SALL4_18804426_ChIP-ChIP_XEN_Mouse0.83614959
152BRD4_27068464_Chip-Seq_AML-cells_Mouse0.83338954
153JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83326501
154EZH2_27294783_Chip-Seq_NPCs_Mouse0.83209903
155SOX2_18555785_Chip-Seq_ESCs_Mouse0.82688916
156PCGF2_27294783_Chip-Seq_ESCs_Mouse0.82558042
157EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.82193857
158ZFX_18555785_Chip-Seq_ESCs_Mouse0.81817196
159NANOG_18555785_Chip-Seq_ESCs_Mouse0.81625055
160TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81559732
161P53_22387025_ChIP-Seq_ESCs_Mouse0.81189442
162OCT4_21477851_ChIP-Seq_ESCs_Mouse0.80904613
163OCT4_18555785_Chip-Seq_ESCs_Mouse0.80673673
164STAT3_18555785_Chip-Seq_ESCs_Mouse0.80350544
165ZNF217_24962896_ChIP-Seq_MCF-7_Human0.80277520
166SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.80208293
167PCGF2_27294783_Chip-Seq_NPCs_Mouse0.79873928
168RUNX1_27457419_Chip-Seq_LIVER_Mouse0.79697456
169KAP1_22055183_ChIP-Seq_ESCs_Mouse0.79387987
170SUZ12_18555785_Chip-Seq_ESCs_Mouse0.79070946
171SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.78464094
172CMYC_18555785_Chip-Seq_ESCs_Mouse0.77939794
173E2F1_18555785_Chip-Seq_ESCs_Mouse0.77527422
174CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.77472598
175SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.77232579
176EGR1_19032775_ChIP-ChIP_M12_Human0.77165168
177OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.77160465
178TP63_23658742_ChIP-Seq_EP156T_Human0.76050695
179PRDM14_20953172_ChIP-Seq_ESCs_Human0.75841915
180SMRT_27268052_Chip-Seq_Bcells_Human0.75770866
181GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75630790
182GATA3_21867929_ChIP-Seq_TH1_Mouse0.75370644
183JUN_21703547_ChIP-Seq_K562_Human0.75352597
184EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.75340567
185LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75294295
186ESRRB_18555785_Chip-Seq_ESCs_Mouse0.75056913

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok6.43646781
2MP0002132_abnormal_respiratory_system5.32719947
3MP0009785_altered_susceptibility_to4.37528767
4MP0003303_peritoneal_inflammation4.33101861
5MP0001984_abnormal_olfaction4.32310815
6MP0003136_yellow_coat_color4.28812818
7MP0006082_CNS_inflammation4.14705271
8MP0004133_heterotaxia3.85392111
9MP0001835_abnormal_antigen_presentation3.81895983
10MP0000566_synostosis3.74949481
11MP0002148_abnormal_hypersensitivity_rea3.69566054
12MP0003436_decreased_susceptibility_to3.67260006
13MP0004043_abnormal_pH_regulation3.53146200
14MP0002277_abnormal_respiratory_mucosa3.38125662
15MP0003878_abnormal_ear_physiology3.33987704
16MP0005377_hearing/vestibular/ear_phenot3.33987704
17MP0008789_abnormal_olfactory_epithelium3.00149481
18MP0002419_abnormal_innate_immunity2.92767431
19MP0005025_abnormal_response_to2.90911529
20MP0005000_abnormal_immune_tolerance2.86730315
21MP0009780_abnormal_chondrocyte_physiolo2.82668475
22MP0003724_increased_susceptibility_to2.76927474
23MP0009764_decreased_sensitivity_to2.64671128
24MP0004019_abnormal_vitamin_homeostasis2.58935334
25MP0004510_myositis2.50013305
26MP0003075_altered_response_to2.35971606
27MP0003690_abnormal_glial_cell2.34545148
28MP0003806_abnormal_nucleotide_metabolis2.32373539
29MP0001853_heart_inflammation2.31449487
30MP0005167_abnormal_blood-brain_barrier2.30328409
31MP0005387_immune_system_phenotype2.29784829
32MP0001790_abnormal_immune_system2.29784829
33MP0005671_abnormal_response_to2.20797269
34MP0005623_abnormal_meninges_morphology2.19658264
35MP0002452_abnormal_antigen_presenting2.15831861
36MP0002160_abnormal_reproductive_system2.08766470
37MP0002723_abnormal_immune_serum2.02665667
38MP0000343_altered_response_to2.01358109
39MP0002405_respiratory_system_inflammati2.00629195
40MP0005394_taste/olfaction_phenotype1.97242810
41MP0005499_abnormal_olfactory_system1.97242810
42MP0001533_abnormal_skeleton_physiology1.92574163
43MP0000685_abnormal_immune_system1.90458434
44MP0004782_abnormal_surfactant_physiolog1.76332303
45MP0005166_decreased_susceptibility_to1.69950811
46MP0001765_abnormal_ion_homeostasis1.67920306
47MP0008004_abnormal_stomach_pH1.66561741
48MP0001800_abnormal_humoral_immune1.64541932
49MP0001819_abnormal_immune_cell1.64016385
50MP0002254_reproductive_system_inflammat1.63165119
51MP0001501_abnormal_sleep_pattern1.62474621
52MP0001845_abnormal_inflammatory_respons1.57685849
53MP0002420_abnormal_adaptive_immunity1.56527521
54MP0001851_eye_inflammation1.56006757
55MP0010678_abnormal_skin_adnexa1.55396108
56MP0004947_skin_inflammation1.52669046
57MP0005164_abnormal_response_to1.50336060
58MP0008469_abnormal_protein_level1.46685662
59MP0002734_abnormal_mechanical_nocicepti1.44825971
60MP0004858_abnormal_nervous_system1.41585646
61MP0003448_altered_tumor_morphology1.41181366
62MP0005646_abnormal_pituitary_gland1.40750791
63MP0005083_abnormal_biliary_tract1.37990086
64MP0001485_abnormal_pinna_reflex1.36532255
65MP0002909_abnormal_adrenal_gland1.35794977
66MP0002998_abnormal_bone_remodeling1.34617609
67MP0001440_abnormal_grooming_behavior1.33433068
68MP0002735_abnormal_chemical_nociception1.33105773
69MP0010030_abnormal_orbit_morphology1.32088571
70MP0002006_tumorigenesis1.31642855
71MP0003186_abnormal_redox_activity1.28894380
72MP0000678_abnormal_parathyroid_gland1.25174898
73MP0002332_abnormal_exercise_endurance1.23435492
74MP0001545_abnormal_hematopoietic_system1.23426922
75MP0005397_hematopoietic_system_phenotyp1.23426922
76MP0002653_abnormal_ependyma_morphology1.22446243
77MP0001346_abnormal_lacrimal_gland1.20802963
78MP0005408_hypopigmentation1.17181800
79MP0000604_amyloidosis1.16787878
80MP0010155_abnormal_intestine_physiology1.16087715
81MP0005464_abnormal_platelet_physiology1.14331816
82MP0005058_abnormal_lysosome_morphology1.12745323
83MP0005636_abnormal_mineral_homeostasis1.11167782
84MP0009840_abnormal_foam_cell1.10416245
85MP0002249_abnormal_larynx_morphology1.10005458
86MP0002233_abnormal_nose_morphology1.07257415
87MP0002138_abnormal_hepatobiliary_system1.03903006
88MP0000858_altered_metastatic_potential1.03673199
89MP0005389_reproductive_system_phenotype1.01571493
90MP0005248_abnormal_Harderian_gland0.99834424
91MP0002133_abnormal_respiratory_system0.98995542
92MP0005388_respiratory_system_phenotype0.98995542
93MP0009765_abnormal_xenobiotic_induced0.94093892
94MP0009763_increased_sensitivity_to0.93710056
95MP0005365_abnormal_bile_salt0.93550534
96MP0001663_abnormal_digestive_system0.92215782
97MP0005310_abnormal_salivary_gland0.92190756
98MP0002282_abnormal_trachea_morphology0.91355016
99MP0000716_abnormal_immune_system0.90019069
100MP0005390_skeleton_phenotype0.87321238
101MP0009379_abnormal_foot_pigmentation0.86547406
102MP0000026_abnormal_inner_ear0.85756013
103MP0001849_ear_inflammation0.84022469
104MP0002822_catalepsy0.83975050
105MP0002928_abnormal_bile_duct0.81252399
106MP0005503_abnormal_tendon_morphology0.80848590
107MP0002876_abnormal_thyroid_physiology0.80573420
108MP0003828_pulmonary_edema0.79569442
109MP0001958_emphysema0.79165698
110MP0004883_abnormal_blood_vessel0.79120955
111MP0001324_abnormal_eye_pigmentation0.76831980
112MP0000465_gastrointestinal_hemorrhage0.76630527
113MP0005220_abnormal_exocrine_pancreas0.75616122
114MP0005165_increased_susceptibility_to0.75025942
115MP0002168_other_aberrant_phenotype0.73170758
116MP0005253_abnormal_eye_physiology0.72849865
117MP0003698_abnormal_male_reproductive0.71589107
118MP0009643_abnormal_urine_homeostasis0.71491294
119MP0005085_abnormal_gallbladder_physiolo0.70128514
120MP0004381_abnormal_hair_follicle0.68570191
121MP0003634_abnormal_glial_cell0.68160849
122MP0003453_abnormal_keratinocyte_physiol0.67364355
123MP0002295_abnormal_pulmonary_circulatio0.67065365
124MP0003091_abnormal_cell_migration0.66520666
125MP0002098_abnormal_vibrissa_morphology0.64974406
126MP0001929_abnormal_gametogenesis0.64482569
127MP0000383_abnormal_hair_follicle0.64350687
128MP0003938_abnormal_ear_development0.61405014
129MP0002736_abnormal_nociception_after0.61247475
130MP0003937_abnormal_limbs/digits/tail_de0.61117286
131MP0005551_abnormal_eye_electrophysiolog0.60482751
132MP0010234_abnormal_vibrissa_follicle0.60211385
133MP0004808_abnormal_hematopoietic_stem0.59869384
134MP0002896_abnormal_bone_mineralization0.59856036
135MP0009278_abnormal_bone_marrow0.59853557
136MP0000681_abnormal_thyroid_gland0.59720704
137MP0009046_muscle_twitch0.59258772
138MP0005595_abnormal_vascular_smooth0.58732919
139MP0001968_abnormal_touch/_nociception0.57280407
140MP0002090_abnormal_vision0.57102999
141MP0001963_abnormal_hearing_physiology0.55935718
142MP0000249_abnormal_blood_vessel0.55626321
143MP0001502_abnormal_circadian_rhythm0.55483612
144MP0001486_abnormal_startle_reflex0.54278344
145MP0005395_other_phenotype0.53744473
146MP0002136_abnormal_kidney_physiology0.53667261
147MP0002398_abnormal_bone_marrow0.53598635
148MP0002102_abnormal_ear_morphology0.53517502
149MP0002638_abnormal_pupillary_reflex0.53458982
150MP0008873_increased_physiological_sensi0.53323970
151MP0009703_decreased_birth_body0.53222999
152MP0003866_abnormal_defecation0.53038527
153MP0005187_abnormal_penis_morphology0.52600512
154MP0001970_abnormal_pain_threshold0.52491191
155MP0003566_abnormal_cell_adhesion0.52490216
156MP0002429_abnormal_blood_cell0.52419795
157MP0002116_abnormal_craniofacial_bone0.52264865
158MP0001293_anophthalmia0.51733167
159MP0003646_muscle_fatigue0.51345727
160MP0001664_abnormal_digestion0.51250606
161MP0000920_abnormal_myelination0.50778904
162MP0003879_abnormal_hair_cell0.50593629
163MP0003656_abnormal_erythrocyte_physiolo0.50099940
164MP0009333_abnormal_splenocyte_physiolog0.49772673
165MP0002166_altered_tumor_susceptibility0.48622036
166MP0002229_neurodegeneration0.48317436
167MP0008874_decreased_physiological_sensi0.47823673
168MP0002139_abnormal_hepatobiliary_system0.45157542
169MP0006036_abnormal_mitochondrial_physio0.44945794
170MP0003942_abnormal_urinary_system0.44895780
171MP0005381_digestive/alimentary_phenotyp0.44433970
172MP0003283_abnormal_digestive_organ0.44022548
173MP0005195_abnormal_posterior_eye0.43951775
174MP0000467_abnormal_esophagus_morphology0.43322314
175MP0004264_abnormal_extraembryonic_tissu0.43035542

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)8.27951625
2Dynein arm defect of respiratory motile cilia (HP:0012255)7.10274173
3Absent/shortened dynein arms (HP:0200106)7.10274173
4Abnormal respiratory epithelium morphology (HP:0012253)6.97029893
5Abnormal respiratory motile cilium morphology (HP:0005938)6.97029893
6Chronic bronchitis (HP:0004469)5.66030534
7Nasal polyposis (HP:0100582)4.97426965
8Bronchiectasis (HP:0002110)4.93095829
9Recurrent abscess formation (HP:0002722)4.90228338
10Recurrent gram-negative bacterial infections (HP:0005420)4.82866338
11Recurrent sinusitis (HP:0011108)4.66345692
12Eczematoid dermatitis (HP:0000976)4.52810895
13Abnormality of the nasal mucosa (HP:0000433)4.23186337
14Infertility (HP:0000789)4.17836462
15Recurrent bacterial skin infections (HP:0005406)3.93003832
16Mediastinal lymphadenopathy (HP:0100721)3.85824806
17Male infertility (HP:0003251)3.43910560
18Obstructive lung disease (HP:0006536)3.40385948
19Chronic obstructive pulmonary disease (HP:0006510)3.40385948
20Autoimmune thrombocytopenia (HP:0001973)3.40227265
21True hermaphroditism (HP:0010459)3.39157181
22Bronchitis (HP:0012387)3.29737135
23Nephronophthisis (HP:0000090)3.20989591
24Abnormality of macrophages (HP:0004311)3.17895314
25Tubular atrophy (HP:0000092)3.13566312
26Pancreatic fibrosis (HP:0100732)2.99586654
27Neoplasm of head and neck (HP:0012288)2.98502409
28Esophageal neoplasm (HP:0100751)2.98502409
29Chronic sinusitis (HP:0011109)2.92337071
30Atelectasis (HP:0100750)2.91232950
31Gastrointestinal infarctions (HP:0005244)2.78098442
32Systemic lupus erythematosus (HP:0002725)2.69456186
33Elevated erythrocyte sedimentation rate (HP:0003565)2.60499147
34Gingivitis (HP:0000230)2.55680451
35Basal ganglia calcification (HP:0002135)2.55326543
36Abnormal biliary tract physiology (HP:0012439)2.53993861
37Bile duct proliferation (HP:0001408)2.53993861
38Chronic hepatic failure (HP:0100626)2.53454188
39Hyperactive renin-angiotensin system (HP:0000841)2.52549570
40Stomatitis (HP:0010280)2.43291602
41Increased IgM level (HP:0003496)2.38624712
42Abnormality of the renal medulla (HP:0100957)2.37511352
43Pancreatic cysts (HP:0001737)2.34540950
44Recurrent skin infections (HP:0001581)2.34269111
45Congenital hepatic fibrosis (HP:0002612)2.32101448
46Recurrent otitis media (HP:0000403)2.25186532
47Recurrent fungal infections (HP:0002841)2.20494993
48Medial flaring of the eyebrow (HP:0010747)2.19201511
49Tubulointerstitial nephritis (HP:0001970)2.11898775
50Prostate neoplasm (HP:0100787)2.10943446
51Occipital encephalocele (HP:0002085)2.06702336
52Vasculitis (HP:0002633)2.05462097
53Abnormality of the renal cortex (HP:0011035)2.01767878
54Male pseudohermaphroditism (HP:0000037)2.01696830
55Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.1391937
56Abnormal respiratory motile cilium physiology (HP:0012261)10.6681192
57Abnormal ciliary motility (HP:0012262)10.5722720
58Porencephaly (HP:0002132)1.98150347
59Thick nail (HP:0001805)1.92625935
60Recurrent pneumonia (HP:0006532)1.92516186
61Postaxial foot polydactyly (HP:0001830)1.90017832
62Congenital primary aphakia (HP:0007707)1.87938391
63Stage 5 chronic kidney disease (HP:0003774)1.86188444
64Oculomotor apraxia (HP:0000657)1.85603006
65Aplasia/Hypoplasia of the tongue (HP:0010295)1.85548164
66Gait imbalance (HP:0002141)1.85525388
67Furrowed tongue (HP:0000221)1.84283085
68Abnormality of midbrain morphology (HP:0002418)1.82193018
69Molar tooth sign on MRI (HP:0002419)1.82193018
70Absent frontal sinuses (HP:0002688)1.79514772
71Vacuolated lymphocytes (HP:0001922)1.78575202
72Chronic otitis media (HP:0000389)1.78515173
73Anencephaly (HP:0002323)1.77874518
74Cellulitis (HP:0100658)1.77083931
75Bell-shaped thorax (HP:0001591)1.76803917
76Abnormal sex determination (HP:0012244)1.76463309
77Sex reversal (HP:0012245)1.76463309
78Cystic liver disease (HP:0006706)1.76052006
79Increased cerebral lipofuscin (HP:0011813)1.73075235
80Increased neuronal autofluorescent lipopigment (HP:0002074)1.72526178
81Tubulointerstitial abnormality (HP:0001969)1.72464428
82Recurrent bronchitis (HP:0002837)1.72208203
83Pustule (HP:0200039)1.69261759
84Poor head control (HP:0002421)1.64556678
85Abnormal drinking behavior (HP:0030082)1.64493179
86Polydipsia (HP:0001959)1.64493179
87Petechiae (HP:0000967)1.63157176
88Abnormality of dentin (HP:0010299)1.63121233
89Postaxial hand polydactyly (HP:0001162)1.62632999
90Recurrent lower respiratory tract infections (HP:0002783)1.61693142
91Nephrogenic diabetes insipidus (HP:0009806)1.61339925
92Median cleft lip (HP:0000161)1.61213738
93Sclerocornea (HP:0000647)1.59826777
94Short nail (HP:0001799)1.58686752
95Nephropathy (HP:0000112)1.58460505
96Asplenia (HP:0001746)1.58113001
97Myocardial infarction (HP:0001658)1.57254598
98Recurrent cutaneous fungal infections (HP:0011370)1.57175030
99Chronic mucocutaneous candidiasis (HP:0002728)1.57175030
100Aplasia/Hypoplasia of the spleen (HP:0010451)1.56812437
101Recurrent viral infections (HP:0004429)1.56068325
102Tetraparesis (HP:0002273)1.54588884
103Decreased circulating renin level (HP:0003351)1.54546106
104Urticaria (HP:0001025)1.52492405
105Abnormality of abdominal situs (HP:0011620)1.52266146
106Abdominal situs inversus (HP:0003363)1.52266146
107Neonatal short-limb short stature (HP:0008921)1.50988856
108Axonal loss (HP:0003447)1.50412553
109Hypertensive crisis (HP:0100735)1.49625035
110Renal salt wasting (HP:0000127)1.49156115
111Meningitis (HP:0001287)1.47499846
112Portal hypertension (HP:0001409)1.47393507
113Interstitial pulmonary disease (HP:0006530)1.45824879
114Orchitis (HP:0100796)1.44010580
115Periodontitis (HP:0000704)1.43368409
116Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.42802214
117Nephritis (HP:0000123)1.42511084
118Hematochezia (HP:0002573)1.41363458
119Progressive inability to walk (HP:0002505)1.41337460
120Abnormality of the dental root (HP:0006486)1.41100755
121Taurodontia (HP:0000679)1.41100755
122Abnormality of permanent molar morphology (HP:0011071)1.41100755
123Leukocytosis (HP:0001974)1.40712938
124Preaxial hand polydactyly (HP:0001177)1.40346878
125Esophageal varix (HP:0002040)1.40090424
126Poor coordination (HP:0002370)1.37459113
127Vaginal atresia (HP:0000148)1.32853091
128Genital tract atresia (HP:0001827)1.30640661
129Abnormality of molar morphology (HP:0011070)1.30108052
130Abnormality of molar (HP:0011077)1.30108052
131Hyperkalemia (HP:0002153)1.29941613
132Supernumerary spleens (HP:0009799)1.26031741
133Abnormality of the dental pulp (HP:0006479)1.25189018
134Absent rod-and cone-mediated responses on ERG (HP:0007688)1.24755513
135Tubulointerstitial fibrosis (HP:0005576)1.24295869
136Hyperaldosteronism (HP:0000859)1.22355754
137Bifid scrotum (HP:0000048)1.19366326
138Cone-rod dystrophy (HP:0000548)1.16043061
139Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.13955588
140Abnormality of the frontal sinuses (HP:0002687)1.13916371
141Short thorax (HP:0010306)1.13841815
142Nonprogressive disorder (HP:0003680)1.11620348
143Abnormality of renin-angiotensin system (HP:0000847)1.11546871
144Abnormality of chloride homeostasis (HP:0011422)1.11119468
145Decreased central vision (HP:0007663)1.09696689
146Broad distal phalanx of finger (HP:0009836)1.08795728
147Abnormality of the distal phalanges of the toes (HP:0010182)1.01793666
148Narrow forehead (HP:0000341)1.00694885
149Glucose intolerance (HP:0000833)0.98962804
150Retinitis pigmentosa (HP:0000510)0.98782790
151Hypokalemic alkalosis (HP:0001949)0.98230788
152Ventricular fibrillation (HP:0001663)0.97372350
153Prominent nasal bridge (HP:0000426)0.92482784
154Absent speech (HP:0001344)0.92276497

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK154.57660432
2EPHA24.34049330
3BLK4.04575044
4MAP3K144.00843779
5PBK3.54265204
6RIPK43.32149510
7MST42.83670888
8MAPKAPK32.80738845
9TBK12.78120996
10PNCK2.76364291
11IRAK42.42494495
12MAP3K22.21593445
13IKBKE2.14504501
14SIK32.13717060
15SIK12.10892363
16JAK32.10492366
17RPS6KA42.01336355
18PIM21.94855136
19CCNB11.89711625
20SIK21.89564801
21IRAK31.89221919
22TYK21.88474572
23NME11.88414524
24NEK91.84071352
25EEF2K1.81367951
26BMPR21.78701364
27STK241.72038192
28IKBKB1.65585371
29TTK1.63731116
30SMG11.54644147
31ERN11.47457613
32MKNK21.47275989
33MAP3K131.44925053
34MOS1.43519359
35DMPK1.38996498
36FES1.31763674
37MAP3K31.29223565
38ABL21.29165580
39FGR1.28164932
40BMX1.26430758
41BCR1.24434480
42NEK61.22456534
43JAK11.22440923
44EPHB11.22147562
45GRK11.18933643
46IRAK11.18827175
47CSK1.17766446
48KIT1.11596841
49TLK11.10247789
50NME21.04170149
51ARAF1.01483050
52MAP3K91.00721375
53MARK30.99818878
54VRK10.98100365
55LATS10.90110636
56STK100.87858346
57HCK0.87387356
58CAMKK10.85945365
59CASK0.84282498
60STK160.84237425
61MAP3K70.83737852
62CHUK0.83500987
63LYN0.81033073
64PLK20.80392955
65STK380.79232062
66TAOK30.78452883
67MARK20.78448258
68ABL10.77897102
69MST1R0.76001749
70ADRBK20.72973495
71MATK0.72386137
72INSRR0.72169216
73IRAK20.71219567
74JAK20.70814161
75EIF2AK20.70604555
76MUSK0.70402612
77TEC0.69720176
78YES10.69468257
79GRK70.68098880
80NTRK20.67751691
81ICK0.67563977
82RPS6KA20.67293393
83EPHA30.66460860
84PRKCI0.65384244
85PAK20.62717776
86STK38L0.62102800
87LCK0.61400679
88PIM10.60895282
89MAP3K40.60448579
90MAP3K50.60214607
91ERBB20.59561386
92MAP3K120.59433945
93AURKA0.57561734
94SCYL20.56921687
95TXK0.56820038
96TAOK10.55245470
97TRPM70.55189118
98PRKCQ0.55166776
99PASK0.54752405
100BRSK20.54519257
101EGFR0.53400773
102NTRK10.52214307
103BTK0.52042194
104SYK0.51614627
105RPS6KA50.50739129
106MKNK10.50711896
107PRKCE0.49344976
108RPS6KB20.47313684
109GSK3A0.46878107
110PRKCD0.46786907
111PRKG20.45346026
112PTK2B0.44470241
113ERBB30.43728173
114TESK10.41157724
115DYRK20.40114759
116MAPKAPK20.39956866
117PTK60.39071827
118DAPK30.36592657
119CAMK2G0.36390672
120MAP2K70.36239074
121SRC0.36058055
122DYRK1B0.35258075
123DAPK20.34909870
124ERBB40.34897969
125CAMKK20.34644679
126FYN0.34465948
127STK40.33583040
128MAP2K20.33529691
129OXSR10.31992161
130PRKAA20.31778647
131CDC42BPA0.31385673
132PRKG10.31277069
133GRK60.30789705
134CDK190.30544156
135ZAP700.29844360
136SGK10.29641627
137RPS6KA60.29619216
138AKT20.29559338
139ADRBK10.29509574
140WNK40.28963912
141STK390.28889813
142HIPK20.27746012
143PRKACA0.26449179
144LRRK20.26237419
145NLK0.25997945
146DYRK30.25931297
147TRIB30.25714629
148MAPK40.25433544
149BMPR1B0.25174425
150PDPK10.24767630
151PINK10.24352517
152ROCK10.24036774
153IGF1R0.23664127
154KSR20.23188635
155PRKCA0.22821090
156MAP4K10.22216815
157MAP2K40.22168589
158MAPKAPK50.21986799
159MYLK0.21566408
160ROCK20.20597159
161RET0.19213989
162DYRK1A0.18627166
163FGFR30.17804973
164FRK0.16483007
165PRKCZ0.15433353
166FER0.14785817
167TSSK60.14743301
168PAK40.14734188
169EPHA40.14529861
170CAMK2A0.14202025
171LATS20.13201567
172WNK30.12953411
173NTRK30.12838512

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009805.79860039
2Chemical carcinogenesis_Homo sapiens_hsa052044.75075459
3Phenylalanine metabolism_Homo sapiens_hsa003604.69938148
4Drug metabolism - cytochrome P450_Homo sapiens_hsa009824.55759984
5Tyrosine metabolism_Homo sapiens_hsa003503.68635355
6Graft-versus-host disease_Homo sapiens_hsa053323.52557023
7Huntingtons disease_Homo sapiens_hsa050163.21865562
8Leishmaniasis_Homo sapiens_hsa051403.14369025
9Glutathione metabolism_Homo sapiens_hsa004802.98100297
10Allograft rejection_Homo sapiens_hsa053302.97738490
11beta-Alanine metabolism_Homo sapiens_hsa004102.93403157
12Toll-like receptor signaling pathway_Homo sapiens_hsa046202.87823987
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.60819143
14Malaria_Homo sapiens_hsa051442.57164820
15Legionellosis_Homo sapiens_hsa051342.54817745
16Rheumatoid arthritis_Homo sapiens_hsa053232.47684070
17NOD-like receptor signaling pathway_Homo sapiens_hsa046212.47681696
18Pertussis_Homo sapiens_hsa051332.44627437
19African trypanosomiasis_Homo sapiens_hsa051432.43683709
20Retinol metabolism_Homo sapiens_hsa008302.30869585
21Staphylococcus aureus infection_Homo sapiens_hsa051502.30818825
22Type I diabetes mellitus_Homo sapiens_hsa049402.27725328
23Asthma_Homo sapiens_hsa053102.23203364
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.07956905
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.07828478
26TNF signaling pathway_Homo sapiens_hsa046681.97673178
27Tuberculosis_Homo sapiens_hsa051521.94782213
28Salmonella infection_Homo sapiens_hsa051321.92175447
29NF-kappa B signaling pathway_Homo sapiens_hsa040641.89055981
30Osteoclast differentiation_Homo sapiens_hsa043801.86131684
31Phagosome_Homo sapiens_hsa041451.81101502
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.77562884
33Influenza A_Homo sapiens_hsa051641.75475041
34Measles_Homo sapiens_hsa051621.70405463
35Linoleic acid metabolism_Homo sapiens_hsa005911.68221432
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.67351546
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.60029926
38Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.59253083
39Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.57073118
40Prion diseases_Homo sapiens_hsa050201.52091709
41Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.46245614
42ABC transporters_Homo sapiens_hsa020101.40691109
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.34929225
44Herpes simplex infection_Homo sapiens_hsa051681.32706092
45Chemokine signaling pathway_Homo sapiens_hsa040621.32158946
46Tight junction_Homo sapiens_hsa045301.29352835
47Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.26542346
48Toxoplasmosis_Homo sapiens_hsa051451.25321049
49Antigen processing and presentation_Homo sapiens_hsa046121.21254930
50Hematopoietic cell lineage_Homo sapiens_hsa046401.18828860
51Fatty acid degradation_Homo sapiens_hsa000711.18360067
52Salivary secretion_Homo sapiens_hsa049701.16986747
53Lysosome_Homo sapiens_hsa041421.15497215
54Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.13397197
55AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.12538380
56Jak-STAT signaling pathway_Homo sapiens_hsa046301.07137583
57B cell receptor signaling pathway_Homo sapiens_hsa046621.06700211
58Amoebiasis_Homo sapiens_hsa051461.05424730
59Peroxisome_Homo sapiens_hsa041461.05189516
60Dorso-ventral axis formation_Homo sapiens_hsa043201.03670929
61Carbohydrate digestion and absorption_Homo sapiens_hsa049731.02362316
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.01433433
63Apoptosis_Homo sapiens_hsa042100.98892923
64Starch and sucrose metabolism_Homo sapiens_hsa005000.98804439
65Viral myocarditis_Homo sapiens_hsa054160.96537492
66Hepatitis B_Homo sapiens_hsa051610.96395233
67Arachidonic acid metabolism_Homo sapiens_hsa005900.88331565
68Autoimmune thyroid disease_Homo sapiens_hsa053200.83916774
69Notch signaling pathway_Homo sapiens_hsa043300.79654736
70Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.74831304
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.71992603
72Olfactory transduction_Homo sapiens_hsa047400.71427865
73Leukocyte transendothelial migration_Homo sapiens_hsa046700.71395832
74Primary bile acid biosynthesis_Homo sapiens_hsa001200.71097242
75Mineral absorption_Homo sapiens_hsa049780.69902707
76Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69527988
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.68140407
78Complement and coagulation cascades_Homo sapiens_hsa046100.67350594
79Ether lipid metabolism_Homo sapiens_hsa005650.67147563
80Collecting duct acid secretion_Homo sapiens_hsa049660.66879881
81Hedgehog signaling pathway_Homo sapiens_hsa043400.66539229
82Hepatitis C_Homo sapiens_hsa051600.66367156
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.65112984
84Nicotine addiction_Homo sapiens_hsa050330.63974132
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63974053
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61102959
87Taste transduction_Homo sapiens_hsa047420.58410848
88Basal cell carcinoma_Homo sapiens_hsa052170.56387580
89Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.55768947
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.54091907
91Sphingolipid signaling pathway_Homo sapiens_hsa040710.54080513
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.51321834
93Choline metabolism in cancer_Homo sapiens_hsa052310.50182305
94Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49932853
95Shigellosis_Homo sapiens_hsa051310.47995702
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47717986
97T cell receptor signaling pathway_Homo sapiens_hsa046600.47545773
98Platelet activation_Homo sapiens_hsa046110.46642487
99Phototransduction_Homo sapiens_hsa047440.45284065
100Prolactin signaling pathway_Homo sapiens_hsa049170.43518664
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43226945
102Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42650275
103Nitrogen metabolism_Homo sapiens_hsa009100.42626365
104Primary immunodeficiency_Homo sapiens_hsa053400.42509419
105Estrogen signaling pathway_Homo sapiens_hsa049150.42281320
106Vitamin B6 metabolism_Homo sapiens_hsa007500.40453244
107Insulin resistance_Homo sapiens_hsa049310.40263206
108Type II diabetes mellitus_Homo sapiens_hsa049300.40002688
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.37482527
110Glycerolipid metabolism_Homo sapiens_hsa005610.36918437
111Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36811652
112Pancreatic secretion_Homo sapiens_hsa049720.35553888
113Tryptophan metabolism_Homo sapiens_hsa003800.35482293
114Metabolic pathways_Homo sapiens_hsa011000.34695132
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34267910
116Histidine metabolism_Homo sapiens_hsa003400.34079634
117Adherens junction_Homo sapiens_hsa045200.33624968
118Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.31977258
119GABAergic synapse_Homo sapiens_hsa047270.31510940
120Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30572690
121Calcium signaling pathway_Homo sapiens_hsa040200.30205033
122Glycosaminoglycan degradation_Homo sapiens_hsa005310.30076497
123PPAR signaling pathway_Homo sapiens_hsa033200.28569470
124Arginine biosynthesis_Homo sapiens_hsa002200.28060827
125Arginine and proline metabolism_Homo sapiens_hsa003300.27936711
126Serotonergic synapse_Homo sapiens_hsa047260.27828447
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.27204852
128Cocaine addiction_Homo sapiens_hsa050300.26692982
129Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.25601447
130Caffeine metabolism_Homo sapiens_hsa002320.25354843
131cAMP signaling pathway_Homo sapiens_hsa040240.25254739
132Renal cell carcinoma_Homo sapiens_hsa052110.24988853
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.24584730
134Gastric acid secretion_Homo sapiens_hsa049710.23904478
135Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.23885325
136Cardiac muscle contraction_Homo sapiens_hsa042600.23404155
137Morphine addiction_Homo sapiens_hsa050320.22892372
138Hippo signaling pathway_Homo sapiens_hsa043900.22597012
139Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.22370944
140Other glycan degradation_Homo sapiens_hsa005110.22183300
141Proteoglycans in cancer_Homo sapiens_hsa052050.21744466
142Glutamatergic synapse_Homo sapiens_hsa047240.21606673
143Sphingolipid metabolism_Homo sapiens_hsa006000.21209462
144Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21114602
145Acute myeloid leukemia_Homo sapiens_hsa052210.20591679
146HTLV-I infection_Homo sapiens_hsa051660.20326970
147Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.19643346
148MAPK signaling pathway_Homo sapiens_hsa040100.17880018
149Transcriptional misregulation in cancer_Homo sapiens_hsa052020.17366315
150Bile secretion_Homo sapiens_hsa049760.17260554
151Purine metabolism_Homo sapiens_hsa002300.17206387
152HIF-1 signaling pathway_Homo sapiens_hsa040660.17097637
153Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.16633864
154Circadian rhythm_Homo sapiens_hsa047100.16201550
155Regulation of actin cytoskeleton_Homo sapiens_hsa048100.15964243
156Butanoate metabolism_Homo sapiens_hsa006500.15943325
157Ovarian steroidogenesis_Homo sapiens_hsa049130.15871196
158Renin secretion_Homo sapiens_hsa049240.15780076
159Nucleotide excision repair_Homo sapiens_hsa034200.14217110
160Alzheimers disease_Homo sapiens_hsa050100.13120577
161Pyruvate metabolism_Homo sapiens_hsa006200.12450364
162Prostate cancer_Homo sapiens_hsa052150.12289593
163Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.11371292
164Oxidative phosphorylation_Homo sapiens_hsa001900.11087542

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »