ANKRD9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-myosin filament sliding (GO:0033275)7.81587724
2muscle filament sliding (GO:0030049)7.81587724
3regulation of skeletal muscle contraction (GO:0014819)7.35058734
4sarcomere organization (GO:0045214)7.10999753
5actin-mediated cell contraction (GO:0070252)6.19445968
6skeletal muscle contraction (GO:0003009)5.84762069
7sarcoplasmic reticulum calcium ion transport (GO:0070296)5.82694939
8positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.74573987
9negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.67927666
10myofibril assembly (GO:0030239)5.44798647
11tricarboxylic acid cycle (GO:0006099)5.35194276
12plasma membrane repair (GO:0001778)5.21489526
13creatine metabolic process (GO:0006600)5.03604075
14regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.99138964
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.95060864
16striated muscle contraction (GO:0006941)4.94960032
17carnitine shuttle (GO:0006853)4.94462033
18porphyrin-containing compound biosynthetic process (GO:0006779)4.88200300
19regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.85589730
20negative regulation of potassium ion transmembrane transport (GO:1901380)4.84920340
21cardiac myofibril assembly (GO:0055003)4.84589879
22ATP synthesis coupled proton transport (GO:0015986)4.79056577
23energy coupled proton transport, down electrochemical gradient (GO:0015985)4.79056577
24cardiac muscle contraction (GO:0060048)4.67723915
25regulation of guanylate cyclase activity (GO:0031282)4.66816030
26regulation of coenzyme metabolic process (GO:0051196)4.66055524
27regulation of cofactor metabolic process (GO:0051193)4.66055524
28regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.57098600
29skeletal muscle adaptation (GO:0043501)4.56239102
30tetrapyrrole biosynthetic process (GO:0033014)4.47243396
31heme biosynthetic process (GO:0006783)4.45514344
32regulation of acyl-CoA biosynthetic process (GO:0050812)4.45424605
33actin filament-based movement (GO:0030048)4.39645839
34oxidative phosphorylation (GO:0006119)4.36938348
35cardiac muscle cell development (GO:0055013)4.34890257
36regulation of cell communication by electrical coupling (GO:0010649)4.31780886
37purine nucleotide salvage (GO:0032261)4.31220250
38response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.29261608
39carnitine transmembrane transport (GO:1902603)4.28714843
40mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.27885226
41angiotensin maturation (GO:0002003)4.24747976
42actomyosin structure organization (GO:0031032)4.22135151
43regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.18575450
44respiratory electron transport chain (GO:0022904)4.18176022
45quinone biosynthetic process (GO:1901663)4.17833935
46ubiquinone biosynthetic process (GO:0006744)4.17833935
47regulation of relaxation of muscle (GO:1901077)4.09791044
48electron transport chain (GO:0022900)4.09726650
49protoporphyrinogen IX metabolic process (GO:0046501)4.08631692
50NADH metabolic process (GO:0006734)4.06119330
51amino-acid betaine transport (GO:0015838)4.00804640
52carnitine transport (GO:0015879)4.00804640
53regulation of actin filament-based movement (GO:1903115)3.98632634
54cardiac cell development (GO:0055006)3.96407089
55fatty acid transmembrane transport (GO:1902001)3.96352078
56positive regulation of guanylate cyclase activity (GO:0031284)3.80173435
57mitochondrial fusion (GO:0008053)3.79183158
58glycogen catabolic process (GO:0005980)3.75740570
59heart process (GO:0003015)3.73173640
60heart contraction (GO:0060047)3.73173640
61regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.72915549
62positive regulation of fatty acid beta-oxidation (GO:0032000)3.71794290
63glucan catabolic process (GO:0009251)3.68305209
64IMP metabolic process (GO:0046040)3.66305910
65skeletal muscle tissue regeneration (GO:0043403)3.65132960
66response to muscle activity (GO:0014850)3.59532986
67muscle contraction (GO:0006936)3.56400266
68ubiquinone metabolic process (GO:0006743)3.55852143
69regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.55073563
70response to inactivity (GO:0014854)3.49922814
71porphyrin-containing compound metabolic process (GO:0006778)3.49441135
72fructose metabolic process (GO:0006000)3.45338854
73cardiac muscle tissue morphogenesis (GO:0055008)3.44922583
74protoporphyrinogen IX biosynthetic process (GO:0006782)3.44152561
75ATP biosynthetic process (GO:0006754)3.41117098
76ventricular cardiac muscle cell action potential (GO:0086005)3.40920686
77regulation of mitochondrial translation (GO:0070129)3.38805798
78cellular polysaccharide catabolic process (GO:0044247)3.37920664
79skeletal muscle fiber development (GO:0048741)3.36332715
80cytidine deamination (GO:0009972)3.33194225
81cytidine metabolic process (GO:0046087)3.33194225
82cytidine catabolic process (GO:0006216)3.33194225
83striated muscle cell development (GO:0055002)3.32848574
84regulation of striated muscle contraction (GO:0006942)3.31472123
85positive regulation of fatty acid oxidation (GO:0046321)3.29876780
86oxygen transport (GO:0015671)3.28548240
87muscle fiber development (GO:0048747)3.26826183
88IMP biosynthetic process (GO:0006188)3.25493904
89muscle tissue morphogenesis (GO:0060415)3.25065650
90adult heart development (GO:0007512)3.24412010
91pyrimidine ribonucleoside catabolic process (GO:0046133)3.23704535
92regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.22596016
93positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.21414667
94sodium ion export (GO:0071436)3.20954480
95gas transport (GO:0015669)3.19696903
96glycine transport (GO:0015816)3.18612234
97regulation of ATPase activity (GO:0043462)3.17725689
98regulation of ATP catabolic process (GO:1903289)3.17725689
99polysaccharide catabolic process (GO:0000272)3.15493762
100regulation of sulfur metabolic process (GO:0042762)3.15393288
101heme metabolic process (GO:0042168)3.13745049
102purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.13287699
103purine nucleoside monophosphate biosynthetic process (GO:0009127)3.13287699
104muscle system process (GO:0003012)3.12894396
105purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.07850508
106negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.05113210
107DNA deamination (GO:0045006)3.02841280
108glycolytic process (GO:0006096)3.01863335
109intestinal absorption (GO:0050892)2.99069877
110regulation of cGMP biosynthetic process (GO:0030826)2.98223010
111purine nucleoside triphosphate biosynthetic process (GO:0009145)2.98043996
112striated muscle atrophy (GO:0014891)2.97332147
113cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.97147448
114heart trabecula formation (GO:0060347)2.94823845
115cGMP-mediated signaling (GO:0019934)2.94420651
116regulation of fatty acid oxidation (GO:0046320)2.86751505
117cellular potassium ion homeostasis (GO:0030007)2.85056071
118receptor guanylyl cyclase signaling pathway (GO:0007168)2.84657808
119membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.82056761
120regulation of fatty acid beta-oxidation (GO:0031998)2.81752074
121regulation of systemic arterial blood pressure (GO:0003073)2.81225731
122cytoskeletal anchoring at plasma membrane (GO:0007016)2.77882333
123regulation of systemic arterial blood pressure by hormone (GO:0001990)2.75583332
124regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)2.75583332
125endocrine process (GO:0050886)2.75583332
126regulation of cholesterol homeostasis (GO:2000188)2.73623116
127oxaloacetate metabolic process (GO:0006107)2.72865929
128regulation of the force of heart contraction (GO:0002026)2.72551528
129cardiac muscle hypertrophy (GO:0003300)2.69533719
130positive regulation of sodium ion transport (GO:0010765)2.67623950
131positive regulation of triglyceride metabolic process (GO:0090208)2.66176526
132striated muscle hypertrophy (GO:0014897)2.63391124
133actin filament capping (GO:0051693)2.62800138
134neurotransmitter catabolic process (GO:0042135)2.61801784
135very-low-density lipoprotein particle assembly (GO:0034379)2.58945346
136striated muscle adaptation (GO:0014888)2.58222764
137adhesion of symbiont to host cell (GO:0044650)2.57202977
138virion attachment to host cell (GO:0019062)2.57202977
139positive regulation of synapse maturation (GO:0090129)2.56421176
140arginine metabolic process (GO:0006525)2.54494914
141cell communication involved in cardiac conduction (GO:0086065)2.53619902
142epoxygenase P450 pathway (GO:0019373)2.53267779
143positive regulation of lipid catabolic process (GO:0050996)2.52924417
144glutathione biosynthetic process (GO:0006750)2.52671255
145cardiac conduction (GO:0061337)2.52276959
146actin filament depolymerization (GO:0030042)2.51513398
147diacylglycerol metabolic process (GO:0046339)2.50828244
148regulation of membrane repolarization (GO:0060306)2.49244027
149regulation of cGMP metabolic process (GO:0030823)2.48066193
150cell communication by electrical coupling (GO:0010644)2.47027248
151bundle of His cell to Purkinje myocyte communication (GO:0086069)2.46186579
152regulation of bile acid biosynthetic process (GO:0070857)2.44185448
153desmosome organization (GO:0002934)2.44033944
154epithelial cell-cell adhesion (GO:0090136)2.43679513
155sexual reproduction (GO:0019953)2.43635514
156gluconeogenesis (GO:0006094)2.43211025
157homocysteine metabolic process (GO:0050667)2.41877599
158renal system process involved in regulation of blood volume (GO:0001977)2.40421679
159adhesion of symbiont to host (GO:0044406)2.39000778
160nucleoside diphosphate biosynthetic process (GO:0009133)2.37789393
161positive regulation of cGMP biosynthetic process (GO:0030828)2.35908478
162membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.34399894

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.26118670
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.64059899
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse3.13564846
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.07738220
5MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.87286315
6THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.67470673
7* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.64144472
8* ZNF263_19887448_ChIP-Seq_K562_Human2.61310962
9TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.54026885
10EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.41655724
11FOXM1_23109430_ChIP-Seq_U2OS_Human2.30774679
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.29591702
13MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.26975357
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.23997784
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.21482897
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.19011230
17ERG_21242973_ChIP-ChIP_JURKAT_Human2.18064175
18E2F7_22180533_ChIP-Seq_HELA_Human2.17972352
19ESR2_21235772_ChIP-Seq_MCF-7_Human2.08649123
20* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.05093355
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.00985284
22RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.99330538
23KDM2B_26808549_Chip-Seq_K562_Human1.98920719
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.96230194
25BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.91692674
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.91520654
27* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.89308626
28YY1_22570637_ChIP-Seq_MALME-3M_Human1.86397364
29STAT3_1855785_ChIP-Seq_MESCs_Mouse1.81576876
30VDR_21846776_ChIP-Seq_THP-1_Human1.77923761
31SRY_22984422_ChIP-ChIP_TESTIS_Rat1.76890848
32TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.75596570
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74944006
34* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.73666973
35DNAJC2_21179169_ChIP-ChIP_NT2_Human1.71646731
36SMC4_20622854_ChIP-Seq_HELA_Human1.67721954
37SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.67543300
38CREB1_26743006_Chip-Seq_LNCaP_Human1.66528541
39EZH2_27294783_Chip-Seq_ESCs_Mouse1.66413354
40* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.65782737
41TBX20_22328084_ChIP-Seq_HEART_Mouse1.63174877
42TBX20_22080862_ChIP-Seq_HEART_Mouse1.63174877
43RXR_22158963_ChIP-Seq_LIVER_Mouse1.62234863
44P68_20966046_ChIP-Seq_HELA_Human1.61580029
45BCL6_27268052_Chip-Seq_Bcells_Human1.56431326
46* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.55830396
47DROSHA_22980978_ChIP-Seq_HELA_Human1.54581330
48TP63_17297297_ChIP-ChIP_HaCaT_Human1.53964288
49CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.52438058
50MYC_19030024_ChIP-ChIP_MESCs_Mouse1.51958387
51KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.51356721
52* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.51215043
53* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.51040655
54STAT6_21828071_ChIP-Seq_BEAS2B_Human1.49716198
55SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.49534953
56NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.47582412
57GATA1_22025678_ChIP-Seq_K562_Human1.47466578
58CTCF_21964334_Chip-Seq_Bcells_Human1.45428669
59* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.45371893
60* TET1_21451524_ChIP-Seq_MESCs_Mouse1.45254525
61CDX2_20551321_ChIP-Seq_CACO-2_Human1.44726184
62DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.44388039
63JARID2_20075857_ChIP-Seq_MESCs_Mouse1.43907278
64* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.43875193
65BCOR_27268052_Chip-Seq_Bcells_Human1.43536254
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.43027462
67* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.42388007
68* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.41990496
69* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.41938284
70ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.41505343
71MYC_19079543_ChIP-ChIP_MESCs_Mouse1.41190962
72YY1_21170310_ChIP-Seq_MESCs_Mouse1.40056011
73ELF1_20517297_ChIP-Seq_JURKAT_Human1.39637784
74FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.38441453
75FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.37915825
76EST1_17652178_ChIP-ChIP_JURKAT_Human1.36430582
77RUNX1_27514584_Chip-Seq_MCF-7_Human1.34600210
78TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.34488235
79ZFP281_18757296_ChIP-ChIP_E14_Mouse1.34472890
80RARG_19884340_ChIP-ChIP_MEFs_Mouse1.34381760
81DCP1A_22483619_ChIP-Seq_HELA_Human1.32742777
82MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.32493694
83* LXR_22292898_ChIP-Seq_THP-1_Human1.30920448
84E2F1_20622854_ChIP-Seq_HELA_Human1.29975215
85* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.29670598
86* GATA1_19941827_ChIP-Seq_MEL_Mouse1.29295082
87MTF2_20144788_ChIP-Seq_MESCs_Mouse1.28618970
88XRN2_22483619_ChIP-Seq_HELA_Human1.27651008
89CIITA_25753668_ChIP-Seq_RAJI_Human1.27390809
90EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.27298516
91CTCF_26484167_Chip-Seq_Bcells_Mouse1.27183084
92* SA1_27219007_Chip-Seq_Bcells_Human1.26508424
93* FOXP1_21924763_ChIP-Seq_HESCs_Human1.26504372
94GATA2_19941826_ChIP-Seq_K562_Human1.26209952
95NANOG_18555785_ChIP-Seq_MESCs_Mouse1.26093433
96HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.25490283
97SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.24270037
98JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.24134784
99EZH2_18974828_ChIP-Seq_MESCs_Mouse1.23445912
100RNF2_18974828_ChIP-Seq_MESCs_Mouse1.23445912
101CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.23313054
102* TCF7_22412390_ChIP-Seq_EML_Mouse1.23261671
103* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.22576489
104ATF3_27146783_Chip-Seq_COLON_Human1.22541058
105MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.22422598
106GABP_17652178_ChIP-ChIP_JURKAT_Human1.19892513
107PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.19867700
108CTCF_20526341_ChIP-Seq_ESCs_Human1.19144839
109CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.18298621
110ELK3_25401928_ChIP-Seq_HUVEC_Human1.17216829
111SA1_27219007_Chip-Seq_ERYTHROID_Human1.17192687
112HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16589850
113ESR1_21235772_ChIP-Seq_MCF-7_Human1.15819537
114CTCF_27219007_Chip-Seq_Bcells_Human1.15463022
115OCT4_19829295_ChIP-Seq_ESCs_Human1.14604813
116* KDM2B_26808549_Chip-Seq_DND41_Human1.14520226
117* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.14379681
118RARB_27405468_Chip-Seq_BRAIN_Mouse1.14173636
119PHF8_20622854_ChIP-Seq_HELA_Human1.13617996
120EZH2_22144423_ChIP-Seq_EOC_Human1.12973690
121EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12873887
122P63_26484246_Chip-Seq_KERATINOCYTES_Human1.11651102
123* RACK7_27058665_Chip-Seq_MCF-7_Human1.11646133
124TRIM28_21343339_ChIP-Seq_HEK293_Human1.11639221
125KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.10133285
126MYC_22102868_ChIP-Seq_BL_Human1.09733283
127MAF_26560356_Chip-Seq_TH2_Human1.09202776
128GATA1_19941826_ChIP-Seq_K562_Human1.08963357
129VDR_23849224_ChIP-Seq_CD4+_Human1.08409932
130GATA4_21415370_ChIP-Seq_HL-1_Mouse1.08114377
131SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08067160
132* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.07891390
133* RARA_24833708_ChIP-Seq_LIVER_Mouse1.07390510
134LXR_22158963_ChIP-Seq_LIVER_Mouse1.07332640
135CTCF_18555785_ChIP-Seq_MESCs_Mouse1.07082739
136* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.06885827
137STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.06684067
138GABP_19822575_ChIP-Seq_HepG2_Human1.06571774
139ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.06394059
140NELFA_20434984_ChIP-Seq_ESCs_Mouse1.06179858
141SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.05446475
142RAD21_21589869_ChIP-Seq_MESCs_Mouse1.05120542
143SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.05006457
144TBX5_21415370_ChIP-Seq_HL-1_Mouse1.04546195
145KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.04456694
146* TET1_21490601_ChIP-Seq_MESCs_Mouse1.03632121
147MYC_27129775_Chip-Seq_CORNEA_Mouse1.03476447
148* TP53_20018659_ChIP-ChIP_R1E_Mouse1.03387372
149NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.03256256
150RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.03037707
151TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02955248
152TP53_22127205_ChIP-Seq_IMR90_Human1.02676117
153KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02159476
154SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.02084001
155JARID2_20064375_ChIP-Seq_MESCs_Mouse1.01514167
156* RNF2_27304074_Chip-Seq_ESCs_Mouse1.01445604
157SPI1_20517297_ChIP-Seq_HL60_Human1.00720559
158CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.00346490
159NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.00170400
160MAF_26560356_Chip-Seq_TH1_Human0.99861307
161SMC3_22415368_ChIP-Seq_MEFs_Mouse0.99795961
162TP63_22573176_ChIP-Seq_HFKS_Human0.97952331
163CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97410062
164LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96494460

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue6.56121269
2MP0002837_dystrophic_cardiac_calcinosis5.66075365
3MP0000751_myopathy5.38906648
4MP0000749_muscle_degeneration5.23002463
5MP0004145_abnormal_muscle_electrophysio4.46308063
6MP0004036_abnormal_muscle_relaxation3.85581923
7MP0004084_abnormal_cardiac_muscle3.67518230
8MP0005360_urolithiasis3.48004280
9MP0004215_abnormal_myocardial_fiber3.41451034
10MP0002106_abnormal_muscle_physiology3.26588921
11MP0000747_muscle_weakness3.22713927
12MP0004087_abnormal_muscle_fiber3.11271457
13MP0002269_muscular_atrophy3.10598983
14MP0000750_abnormal_muscle_regeneration3.07837506
15MP0005330_cardiomyopathy3.02551293
16MP0000759_abnormal_skeletal_muscle2.76007370
17MP0003656_abnormal_erythrocyte_physiolo2.75555618
18MP0004147_increased_porphyrin_level2.68511479
19MP0006036_abnormal_mitochondrial_physio2.65488455
20MP0009379_abnormal_foot_pigmentation2.62248255
21MP0005369_muscle_phenotype2.56668298
22MP0005620_abnormal_muscle_contractility2.55183946
23MP0004130_abnormal_muscle_cell2.45485980
24MP0005409_darkened_coat_color2.09903571
25MP0003879_abnormal_hair_cell2.06633392
26MP0005410_abnormal_fertilization2.04785987
27MP0005083_abnormal_biliary_tract2.01537384
28MP0002972_abnormal_cardiac_muscle2.00645303
29MP0002822_catalepsy2.00599972
30MP0008775_abnormal_heart_ventricle1.99881491
31MP0003137_abnormal_impulse_conducting1.99735699
32MP0010630_abnormal_cardiac_muscle1.87735542
33MP0004484_altered_response_of1.80267243
34MP0004233_abnormal_muscle_weight1.78455515
35MP0005385_cardiovascular_system_phenoty1.75904104
36MP0001544_abnormal_cardiovascular_syste1.75904104
37MP0000678_abnormal_parathyroid_gland1.68773690
38MP0006035_abnormal_mitochondrial_morpho1.67439134
39MP0002332_abnormal_exercise_endurance1.61966283
40MP0010234_abnormal_vibrissa_follicle1.61075022
41MP0003221_abnormal_cardiomyocyte_apopto1.58794937
42MP0002249_abnormal_larynx_morphology1.57301282
43MP0001664_abnormal_digestion1.57104004
44MP0000566_synostosis1.55127989
45MP0004270_analgesia1.53695401
46MP0002653_abnormal_ependyma_morphology1.46898679
47MP0005666_abnormal_adipose_tissue1.43584961
48MP0003950_abnormal_plasma_membrane1.43504408
49MP0006138_congestive_heart_failure1.36831957
50MP0004858_abnormal_nervous_system1.34219503
51MP0003136_yellow_coat_color1.33952300
52MP0001666_abnormal_nutrient_absorption1.33885294
53MP0001188_hyperpigmentation1.32100956
54MP0003806_abnormal_nucleotide_metabolis1.31693365
55MP0005365_abnormal_bile_salt1.30585825
56MP0005085_abnormal_gallbladder_physiolo1.30303469
57MP0002139_abnormal_hepatobiliary_system1.29929516
58MP0004185_abnormal_adipocyte_glucose1.24733635
59MP0005332_abnormal_amino_acid1.24312116
60MP0005670_abnormal_white_adipose1.22168725
61MP0000733_abnormal_muscle_development1.21836268
62MP0003828_pulmonary_edema1.21400911
63MP0001849_ear_inflammation1.20094229
64MP0004019_abnormal_vitamin_homeostasis1.16847744
65MP0004264_abnormal_extraembryonic_tissu1.13637185
66MP0003567_abnormal_fetal_cardiomyocyte1.13339053
67MP0005266_abnormal_metabolism1.12599825
68MP0003329_amyloid_beta_deposits1.09839125
69MP0004510_myositis1.07111686
70MP0003183_abnormal_peptide_metabolism1.06153641
71MP0010329_abnormal_lipoprotein_level1.05923434
72MP0005058_abnormal_lysosome_morphology1.05430435
73MP0009780_abnormal_chondrocyte_physiolo1.04764936
74MP0000538_abnormal_urinary_bladder0.98636816
75MP0009643_abnormal_urine_homeostasis0.96227359
76MP0005375_adipose_tissue_phenotype0.95877910
77MP0009840_abnormal_foam_cell0.95120186
78MP0004085_abnormal_heartbeat0.94813268
79MP0000343_altered_response_to0.94050313
80MP0002108_abnormal_muscle_morphology0.90622414
81MP0003705_abnormal_hypodermis_morpholog0.87453148
82MP0002127_abnormal_cardiovascular_syste0.85124365
83MP0004885_abnormal_endolymph0.84200889
84MP0000266_abnormal_heart_morphology0.82839140
85MP0002234_abnormal_pharynx_morphology0.82792336
86MP0002971_abnormal_brown_adipose0.78334789
87MP0002118_abnormal_lipid_homeostasis0.77934484
88MP0001756_abnormal_urination0.77308204
89MP0003453_abnormal_keratinocyte_physiol0.76731626
90MP0005423_abnormal_somatic_nervous0.76015693
91MP0002098_abnormal_vibrissa_morphology0.75839249
92MP0003283_abnormal_digestive_organ0.74290787
93MP0002734_abnormal_mechanical_nocicepti0.73600953
94MP0000534_abnormal_ureter_morphology0.72158952
95MP0005076_abnormal_cell_differentiation0.71893075
96MP0000462_abnormal_digestive_system0.71599349
97MP0002876_abnormal_thyroid_physiology0.71081286
98MP0003111_abnormal_nucleus_morphology0.70273547
99MP0002733_abnormal_thermal_nociception0.70139381
100MP0004859_abnormal_synaptic_plasticity0.68978054
101MP0000358_abnormal_cell_content/0.68715843
102MP0005535_abnormal_body_temperature0.68183551
103MP0004782_abnormal_surfactant_physiolog0.67563090
104MP0005165_increased_susceptibility_to0.67312516
105MP0003693_abnormal_embryo_hatching0.65883943
106MP0003698_abnormal_male_reproductive0.62244792
107MP0001929_abnormal_gametogenesis0.56811273
108MP0010094_abnormal_chromosome_stability0.56323804
109MP0008770_decreased_survivor_rate0.54777698
110MP0005319_abnormal_enzyme/_coenzyme0.52522908
111MP0000003_abnormal_adipose_tissue0.50794740
112MP0005451_abnormal_body_composition0.50115396
113MP0004957_abnormal_blastocyst_morpholog0.49131014
114MP0004043_abnormal_pH_regulation0.46439507
115MP0001730_embryonic_growth_arrest0.45871482
116MP0000537_abnormal_urethra_morphology0.44862826
117MP0005636_abnormal_mineral_homeostasis0.44621710
118MP0005334_abnormal_fat_pad0.43580489
119MP0003077_abnormal_cell_cycle0.43235406
120MP0005623_abnormal_meninges_morphology0.42397629
121MP0001853_heart_inflammation0.41218033
122MP0000230_abnormal_systemic_arterial0.39610365
123MP0005397_hematopoietic_system_phenotyp0.39053471
124MP0001545_abnormal_hematopoietic_system0.39053471
125MP0000313_abnormal_cell_death0.37151796
126MP0002080_prenatal_lethality0.36497617
127MP0003878_abnormal_ear_physiology0.35840986
128MP0005377_hearing/vestibular/ear_phenot0.35840986
129MP0004142_abnormal_muscle_tone0.35219868
130MP0005376_homeostasis/metabolism_phenot0.34839742
131MP0005584_abnormal_enzyme/coenzyme_acti0.34718036
132MP0003984_embryonic_growth_retardation0.33123165
133MP0002078_abnormal_glucose_homeostasis0.33068119
134MP0002970_abnormal_white_adipose0.31832999
135MP0009115_abnormal_fat_cell0.30205645
136MP0001765_abnormal_ion_homeostasis0.30154797
137MP0002088_abnormal_embryonic_growth/wei0.29954792
138MP0000013_abnormal_adipose_tissue0.29736037
139MP0010352_gastrointestinal_tract_polyps0.29099564
140MP0001697_abnormal_embryo_size0.28953519
141MP0003279_aneurysm0.28949315
142MP0005452_abnormal_adipose_tissue0.28750110
143MP0002128_abnormal_blood_circulation0.28230180
144MP0002161_abnormal_fertility/fecundity0.27287164
145MP0001672_abnormal_embryogenesis/_devel0.25389245
146MP0005380_embryogenesis_phenotype0.25389245
147MP0000350_abnormal_cell_proliferation0.24362889

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced myalgia (HP:0003738)7.15011946
2Exercise-induced muscle cramps (HP:0003710)6.73454439
3Muscle hypertrophy of the lower extremities (HP:0008968)6.18174089
4Calf muscle hypertrophy (HP:0008981)5.95226625
5Muscle fiber inclusion bodies (HP:0100299)5.91435162
6Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.79853007
7Muscle fiber splitting (HP:0003555)5.57067169
8Myoglobinuria (HP:0002913)5.42176512
9Nemaline bodies (HP:0003798)5.15704749
10Sudden death (HP:0001699)5.09113683
11Rhabdomyolysis (HP:0003201)4.97578274
12Hyporeflexia of lower limbs (HP:0002600)4.89623040
13Difficulty running (HP:0009046)4.66277181
14Abnormality of the calf musculature (HP:0001430)4.43358347
15Abnormality of glutamine family amino acid metabolism (HP:0010902)4.37755271
16Ventricular tachycardia (HP:0004756)4.36151174
17EMG: myopathic abnormalities (HP:0003458)4.33238336
18Type 1 muscle fiber predominance (HP:0003803)4.21250547
19Muscle stiffness (HP:0003552)4.10701858
20Distal arthrogryposis (HP:0005684)4.03960623
21Myopathic facies (HP:0002058)4.00536225
22Increased connective tissue (HP:0009025)3.97472536
23Difficulty climbing stairs (HP:0003551)3.89812705
24Myotonia (HP:0002486)3.85385529
25Ileus (HP:0002595)3.80455845
26Subaortic stenosis (HP:0001682)3.78482271
27Abnormality of the left ventricular outflow tract (HP:0011103)3.78482271
28Round ear (HP:0100830)3.68406764
29Hydroxyprolinuria (HP:0003080)3.59379575
30Abnormality of proline metabolism (HP:0010907)3.59379575
31Areflexia of lower limbs (HP:0002522)3.41799238
32Lipoatrophy (HP:0100578)3.38390096
33Centrally nucleated skeletal muscle fibers (HP:0003687)3.34560237
34Ulnar deviation of the wrist (HP:0003049)3.26397114
35Asymmetric septal hypertrophy (HP:0001670)3.25633316
36Distal lower limb amyotrophy (HP:0008944)3.20590304
37Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.14067006
38Decreased activity of mitochondrial respiratory chain (HP:0008972)3.14067006
39Dilated cardiomyopathy (HP:0001644)3.09721133
40Progressive muscle weakness (HP:0003323)3.05823951
41Bundle branch block (HP:0011710)2.98775059
42Neck muscle weakness (HP:0000467)2.97594029
43Mildly elevated creatine phosphokinase (HP:0008180)2.91158404
44Atrial fibrillation (HP:0005110)2.90847419
45Abnormality of skeletal muscle fiber size (HP:0012084)2.90570539
46Calcaneovalgus deformity (HP:0001848)2.82755272
47Increased variability in muscle fiber diameter (HP:0003557)2.81308429
48Palpitations (HP:0001962)2.79620494
49Rectal prolapse (HP:0002035)2.76099620
50Hepatocellular necrosis (HP:0001404)2.74954271
51Abnormal mitochondria in muscle tissue (HP:0008316)2.73553177
52Hepatic necrosis (HP:0002605)2.72785532
53Supraventricular tachycardia (HP:0004755)2.72742803
54Right ventricular cardiomyopathy (HP:0011663)2.71941728
55Primary atrial arrhythmia (HP:0001692)2.71814040
56Acute necrotizing encephalopathy (HP:0006965)2.68019796
57Increased muscle lipid content (HP:0009058)2.67367789
58Supraventricular arrhythmia (HP:0005115)2.65468263
59Acanthocytosis (HP:0001927)2.64711875
60Rimmed vacuoles (HP:0003805)2.63782452
61Paralysis (HP:0003470)2.63571827
62Confusion (HP:0001289)2.58079344
63Deformed tarsal bones (HP:0008119)2.56239733
64Malnutrition (HP:0004395)2.54725968
65Exercise intolerance (HP:0003546)2.53712787
66Limb-girdle muscle atrophy (HP:0003797)2.53230375
67Distal lower limb muscle weakness (HP:0009053)2.52814510
68Facial diplegia (HP:0001349)2.51316675
69Abnormality of the heme biosynthetic pathway (HP:0010472)2.50919750
70Cholelithiasis (HP:0001081)2.50762189
71Mitochondrial inheritance (HP:0001427)2.47941839
72Heart block (HP:0012722)2.47575112
73Increased intramyocellular lipid droplets (HP:0012240)2.44769873
74Gowers sign (HP:0003391)2.43288830
75Hyperkalemia (HP:0002153)2.38719468
76Absent phalangeal crease (HP:0006109)2.38715482
77Syncope (HP:0001279)2.36236895
78Testicular atrophy (HP:0000029)2.35630484
79EMG: neuropathic changes (HP:0003445)2.35303865
80Abnormal atrioventricular conduction (HP:0005150)2.33590755
81Lactic acidosis (HP:0003128)2.32876444
82Ventricular arrhythmia (HP:0004308)2.32579764
83Acute encephalopathy (HP:0006846)2.32499844
84Increased CSF lactate (HP:0002490)2.32279389
85Abnormality of alanine metabolism (HP:0010916)2.31906806
86Hyperalaninemia (HP:0003348)2.31906806
87Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.31906806
88Ventricular fibrillation (HP:0001663)2.30173866
89Lower limb amyotrophy (HP:0007210)2.29657202
90Poikilocytosis (HP:0004447)2.29314460
91Muscular dystrophy (HP:0003560)2.27647070
92Ragged-red muscle fibers (HP:0003200)2.25102254
93Generalized muscle weakness (HP:0003324)2.24904783
94Atrioventricular block (HP:0001678)2.24857882
95Prolonged QT interval (HP:0001657)2.19681569
96Stridor (HP:0010307)2.19506297
97Dicarboxylic aciduria (HP:0003215)2.17913838
98Abnormality of dicarboxylic acid metabolism (HP:0010995)2.17913838
99Reticulocytosis (HP:0001923)2.17536344
100Fatigable weakness (HP:0003473)2.16620113
101Abnormality of the neuromuscular junction (HP:0003398)2.16620113
102Diaphragmatic weakness (HP:0009113)2.15576670
103Abnormality of the aortic arch (HP:0012303)2.13835538
104Abnormal gallbladder morphology (HP:0012437)2.11185392
105Abnormality of the musculature of the pelvis (HP:0001469)2.11086246
106Abnormality of the hip-girdle musculature (HP:0001445)2.11086246
107Malignant hyperthermia (HP:0002047)2.10142004
108Pelvic girdle muscle weakness (HP:0003749)2.08985492
109Abnormal EKG (HP:0003115)2.08037905
110Decreased circulating renin level (HP:0003351)2.06940288
111Abnormality of reticulocytes (HP:0004312)2.05962791
112Abnormal finger flexion creases (HP:0006143)2.04465516
113Limb-girdle muscle weakness (HP:0003325)2.03830320
114Bulbar palsy (HP:0001283)2.03361224
115Cerebral edema (HP:0002181)2.01910523
116Progressive macrocephaly (HP:0004481)2.01776895
117Respiratory failure (HP:0002878)1.97973282
118Frequent falls (HP:0002359)1.96687867
119Hemorrhage of the eye (HP:0011885)1.96472079
120Thin bony cortex (HP:0002753)1.93935213
121Foot dorsiflexor weakness (HP:0009027)1.92937978
122Metabolic alkalosis (HP:0200114)1.92893653
123Abnormality of the foot musculature (HP:0001436)1.89752714
124Ankle clonus (HP:0011448)1.87764056
125Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.84358479
126Increased purine levels (HP:0004368)1.83949286
127Hyperuricemia (HP:0002149)1.83949286
128Nausea (HP:0002018)1.83800233
129Cerebral palsy (HP:0100021)1.83302885
130Hyperglycinuria (HP:0003108)1.79047029
131Hyperparathyroidism (HP:0000843)1.78885174
132Polycythemia (HP:0001901)1.78129030
133Widely patent fontanelles and sutures (HP:0004492)1.74833720
134Abnormal hemoglobin (HP:0011902)1.72859868
135Spinal rigidity (HP:0003306)1.72112495
136Abnormality of the gallbladder (HP:0005264)1.71053178
137Abnormality of potassium homeostasis (HP:0011042)1.67993868
138Multiple lipomas (HP:0001012)1.67209765
139Truncus arteriosus (HP:0001660)1.65363165
140Abnormality of renin-angiotensin system (HP:0000847)1.62330524

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.68243175
2OBSCN4.68606092
3PHKG14.23577747
4PHKG24.23577747
5PDK43.82145966
6PDK33.82145966
7RIPK12.67207225
8NME12.53675899
9NEK12.52614359
10NME22.31896019
11TLK12.24993127
12EIF2AK12.24582044
13BUB12.23187550
14PINK12.21599067
15MST1R2.21551176
16MAP2K32.16398894
17PDK22.11558471
18BCKDK2.03860895
19TRIB32.02653184
20MUSK1.95205224
21LMTK21.91662759
22SIK11.77241763
23ACVR1B1.69402897
24ERN11.69119707
25PRPF4B1.62988297
26IRAK31.61315163
27EPHA21.57482473
28ICK1.51670519
29MAPKAPK31.51274571
30MAP3K101.49812632
31MYLK1.47549463
32MAP3K111.45264295
33DMPK1.44153472
34MAP2K21.37351581
35EPHB21.29833204
36WEE11.28983031
37DAPK21.27396403
38BMX1.27273775
39DDR21.23890061
40MET1.20758200
41ZAK1.19231776
42SMG11.18641874
43PTK61.18375389
44MAPK151.17047805
45RPS6KA21.14611398
46PKN21.13960063
47STK41.13657357
48MAPK121.12512048
49MAP3K71.00856457
50RPS6KA61.00591928
51SCYL21.00301394
52RPS6KC10.99884030
53RPS6KL10.99884030
54MAP3K10.96416443
55PIK3CG0.92457810
56PIK3CA0.89244865
57MAP2K60.89182385
58ILK0.89052233
59RPS6KB20.88237246
60PNCK0.86192346
61STK240.85511740
62NEK20.83257288
63DYRK30.82510735
64PRKAA10.79889131
65MAPK110.75587536
66TYRO30.75410879
67MTOR0.74698248
68AKT20.72037005
69KDR0.71707912
70PRKD20.71622426
71MAP3K80.70613994
72SGK4940.70340960
73SGK2230.70340960
74SGK30.69412500
75TESK10.68531451
76PRKAA20.68342442
77ABL20.66907617
78MAP3K50.66044964
79TTK0.65532630
80CAMK40.64080544
81PRKD30.63876674
82HIPK20.62116768
83MAP3K30.61926412
84MAP2K40.60677501
85CAMK2B0.60259204
86CAMK10.59003582
87EEF2K0.58915080
88MARK10.57638135
89GRK70.57497911
90FGFR40.56745552
91WNK10.56610711
92CDK40.55863974
93PDPK10.55804403
94MARK20.54237383
95CDC42BPA0.53545345
96IRAK20.53489408
97STK110.53411624
98CAMK2D0.52978526
99WNK40.52667942
100MAP3K20.51290389
101DAPK30.50072981
102AURKA0.49826706
103CAMK1D0.48230187
104PDK10.48033684
105PTK20.47368556
106EPHA40.45781700
107NTRK10.44718786
108PRKD10.43730071
109GRK50.42543361
110PAK10.42360329
111TAOK10.41916409
112PAK40.41028757
113BRSK10.40675933
114ROCK20.39489468
115MAPK40.39451606
116PAK60.39217311
117BRAF0.38003050
118PRKACG0.37285880
119LATS20.36882389
120KSR20.36370788
121TRPM70.34957680
122PRKCZ0.34788602
123CAMK2G0.32666448
124DYRK1B0.32491185
125LRRK20.31880470
126AURKB0.31269709
127STK160.31146542
128STK390.30804384
129MAP4K10.30196880
130RPS6KA10.29791581
131CHEK20.29627469
132VRK10.29529195
133STK100.27900870
134TESK20.27464272
135EIF2AK30.27307548
136PRKACB0.26100500
137PRKG20.24962050
138GRK60.24946748
139PIM10.23794974
140ROCK10.22123974
141CDK120.22062790
142PKN10.21465862
143ARAF0.20019761
144CDK190.19250531
145MAP2K10.18945393
146PTK2B0.18863079
147PIM20.17890559
148CDK70.17546900
149TAOK20.16814903
150STK380.16459772

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.92052454
2Cardiac muscle contraction_Homo sapiens_hsa042604.10097423
3Parkinsons disease_Homo sapiens_hsa050123.76182733
4Cyanoamino acid metabolism_Homo sapiens_hsa004603.68485262
5Oxidative phosphorylation_Homo sapiens_hsa001903.63681981
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.44857465
7Propanoate metabolism_Homo sapiens_hsa006402.82835559
8Arginine biosynthesis_Homo sapiens_hsa002202.78356419
9Carbon metabolism_Homo sapiens_hsa012002.75906721
10Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.73492015
11Alzheimers disease_Homo sapiens_hsa050102.68872193
12Huntingtons disease_Homo sapiens_hsa050162.60878857
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.49989261
14Dilated cardiomyopathy_Homo sapiens_hsa054142.40164591
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.14532306
16Vitamin digestion and absorption_Homo sapiens_hsa049771.96857298
17Pyruvate metabolism_Homo sapiens_hsa006201.96656219
18Mineral absorption_Homo sapiens_hsa049781.96070764
19Ribosome_Homo sapiens_hsa030101.91780065
20Fatty acid degradation_Homo sapiens_hsa000711.91171786
21Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.82711610
22Proteasome_Homo sapiens_hsa030501.79067129
23Fructose and mannose metabolism_Homo sapiens_hsa000511.74290207
24Bile secretion_Homo sapiens_hsa049761.71655347
25DNA replication_Homo sapiens_hsa030301.69544261
26Histidine metabolism_Homo sapiens_hsa003401.66279129
27Biosynthesis of amino acids_Homo sapiens_hsa012301.64475834
28Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.58223489
29Sulfur relay system_Homo sapiens_hsa041221.55116781
30Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.50910428
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.50699597
32Pentose phosphate pathway_Homo sapiens_hsa000301.46249600
33Carbohydrate digestion and absorption_Homo sapiens_hsa049731.45527337
34Protein digestion and absorption_Homo sapiens_hsa049741.40442207
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.38097888
36Nitrogen metabolism_Homo sapiens_hsa009101.29879935
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28131811
38Fatty acid metabolism_Homo sapiens_hsa012121.25085415
39Glucagon signaling pathway_Homo sapiens_hsa049221.19667967
40Phenylalanine metabolism_Homo sapiens_hsa003601.16663465
41Starch and sucrose metabolism_Homo sapiens_hsa005001.16426547
42Galactose metabolism_Homo sapiens_hsa000521.13963069
43Insulin signaling pathway_Homo sapiens_hsa049101.07734874
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.06478530
45Vitamin B6 metabolism_Homo sapiens_hsa007501.04329567
46Systemic lupus erythematosus_Homo sapiens_hsa053221.03382390
47Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.03227121
48Insulin secretion_Homo sapiens_hsa049111.02327480
49Adipocytokine signaling pathway_Homo sapiens_hsa049200.99956628
50Arginine and proline metabolism_Homo sapiens_hsa003300.97436367
51Sulfur metabolism_Homo sapiens_hsa009200.96676389
52Viral myocarditis_Homo sapiens_hsa054160.91188025
53Pyrimidine metabolism_Homo sapiens_hsa002400.89687058
54Purine metabolism_Homo sapiens_hsa002300.89501946
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88939944
56Mismatch repair_Homo sapiens_hsa034300.87890870
57Fat digestion and absorption_Homo sapiens_hsa049750.87588881
58Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85829996
59Tryptophan metabolism_Homo sapiens_hsa003800.82548695
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80483136
61Fatty acid biosynthesis_Homo sapiens_hsa000610.79984315
62RNA polymerase_Homo sapiens_hsa030200.79485634
63Pancreatic secretion_Homo sapiens_hsa049720.79424255
64Base excision repair_Homo sapiens_hsa034100.78392167
65GnRH signaling pathway_Homo sapiens_hsa049120.76173037
66AMPK signaling pathway_Homo sapiens_hsa041520.76162696
67Gastric acid secretion_Homo sapiens_hsa049710.74280150
68Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73572904
69Renin secretion_Homo sapiens_hsa049240.72887483
70Insulin resistance_Homo sapiens_hsa049310.72266354
71Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.71423891
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70902002
73Maturity onset diabetes of the young_Homo sapiens_hsa049500.69786254
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.69677906
75PPAR signaling pathway_Homo sapiens_hsa033200.69138785
76Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66933242
77HIF-1 signaling pathway_Homo sapiens_hsa040660.66843976
78Notch signaling pathway_Homo sapiens_hsa043300.66299451
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.65198250
80Other glycan degradation_Homo sapiens_hsa005110.63878622
81Metabolic pathways_Homo sapiens_hsa011000.63413576
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.62672798
83Tyrosine metabolism_Homo sapiens_hsa003500.62325281
84Folate biosynthesis_Homo sapiens_hsa007900.62238671
85Arachidonic acid metabolism_Homo sapiens_hsa005900.62160000
86Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60984134
87Calcium signaling pathway_Homo sapiens_hsa040200.58476394
88ABC transporters_Homo sapiens_hsa020100.56079246
89Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55957076
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55682130
91Ether lipid metabolism_Homo sapiens_hsa005650.54175588
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53440476
93Cholinergic synapse_Homo sapiens_hsa047250.53151305
94Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.53019723
95Glutathione metabolism_Homo sapiens_hsa004800.52138139
96Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51976954
97Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.51788295
98Ovarian steroidogenesis_Homo sapiens_hsa049130.49397493
99Oxytocin signaling pathway_Homo sapiens_hsa049210.48978496
100RNA transport_Homo sapiens_hsa030130.48791453
101Non-homologous end-joining_Homo sapiens_hsa034500.47800873
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.46993264
103Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.46659686
104Tight junction_Homo sapiens_hsa045300.46658543
105Chemical carcinogenesis_Homo sapiens_hsa052040.46647009
106Caffeine metabolism_Homo sapiens_hsa002320.46103730
107cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45479972
108Salivary secretion_Homo sapiens_hsa049700.45347224
109Long-term potentiation_Homo sapiens_hsa047200.44021669
110Circadian entrainment_Homo sapiens_hsa047130.43095736
111Homologous recombination_Homo sapiens_hsa034400.42325526
112Spliceosome_Homo sapiens_hsa030400.41766656
113Nucleotide excision repair_Homo sapiens_hsa034200.41679412
114Thyroid hormone synthesis_Homo sapiens_hsa049180.40414396
115Estrogen signaling pathway_Homo sapiens_hsa049150.39860308
116Retinol metabolism_Homo sapiens_hsa008300.39733631
117VEGF signaling pathway_Homo sapiens_hsa043700.39685977
118Synaptic vesicle cycle_Homo sapiens_hsa047210.39003018
119Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38433022
120Amphetamine addiction_Homo sapiens_hsa050310.38227129
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38035535
122Acute myeloid leukemia_Homo sapiens_hsa052210.37731795
123alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37676874
124Melanogenesis_Homo sapiens_hsa049160.37606801
125Prion diseases_Homo sapiens_hsa050200.36841363
126Fatty acid elongation_Homo sapiens_hsa000620.35479134
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.34557865
128Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34318239
129Oocyte meiosis_Homo sapiens_hsa041140.33792991
130Cell cycle_Homo sapiens_hsa041100.33019289
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31758729
132Bladder cancer_Homo sapiens_hsa052190.31461343
133beta-Alanine metabolism_Homo sapiens_hsa004100.29383872
134Vascular smooth muscle contraction_Homo sapiens_hsa042700.28562127
135Linoleic acid metabolism_Homo sapiens_hsa005910.28539723
136Butanoate metabolism_Homo sapiens_hsa006500.28468667
137Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28079972
138Fanconi anemia pathway_Homo sapiens_hsa034600.27444377
139Glycerolipid metabolism_Homo sapiens_hsa005610.24613006
140Regulation of autophagy_Homo sapiens_hsa041400.23102956
141Basal transcription factors_Homo sapiens_hsa030220.22172582
142Selenocompound metabolism_Homo sapiens_hsa004500.21377625
143Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.20079308
144Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.19754466
145Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.18142661
146Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.17640785
147RNA degradation_Homo sapiens_hsa030180.17234279
148Renin-angiotensin system_Homo sapiens_hsa046140.16880559
149Alcoholism_Homo sapiens_hsa050340.16690172
150p53 signaling pathway_Homo sapiens_hsa041150.16340147
151Peroxisome_Homo sapiens_hsa041460.15572385

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