

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | motile cilium assembly (GO:0044458) | 8.81062921 |
| 2 | regulation of cilium movement (GO:0003352) | 6.17181175 |
| 3 | left/right axis specification (GO:0070986) | 5.36014893 |
| 4 | fatty acid elongation (GO:0030497) | 5.35038503 |
| 5 | long-chain fatty acid biosynthetic process (GO:0042759) | 5.34804625 |
| 6 | cilium organization (GO:0044782) | 5.31564374 |
| 7 | myelination (GO:0042552) | 5.25117488 |
| 8 | axon ensheathment (GO:0008366) | 5.20945029 |
| 9 | ensheathment of neurons (GO:0007272) | 5.20945029 |
| 10 | cilium assembly (GO:0042384) | 5.12227790 |
| 11 | left/right pattern formation (GO:0060972) | 5.09341124 |
| 12 | intraciliary transport (GO:0042073) | 4.96935430 |
| 13 | L-amino acid import (GO:0043092) | 4.82052246 |
| 14 | ventricular system development (GO:0021591) | 4.74800726 |
| 15 | protein localization to cilium (GO:0061512) | 4.58841858 |
| 16 | negative regulation of protein localization to cell surface (GO:2000009) | 4.32676067 |
| 17 | microtubule bundle formation (GO:0001578) | 4.31303198 |
| 18 | oligodendrocyte differentiation (GO:0048709) | 4.24270351 |
| 19 | cilium morphogenesis (GO:0060271) | 4.19249214 |
| 20 | negative regulation of neurotransmitter transport (GO:0051589) | 4.15301835 |
| 21 | myelin maintenance (GO:0043217) | 4.14923279 |
| 22 | import into cell (GO:0098657) | 4.11546010 |
| 23 | cellular component assembly involved in morphogenesis (GO:0010927) | 4.01938330 |
| 24 | negative regulation of neurotransmitter secretion (GO:0046929) | 4.00128325 |
| 25 | regulation of microtubule-based movement (GO:0060632) | 3.95942946 |
| 26 | behavioral response to nicotine (GO:0035095) | 3.92095020 |
| 27 | presynaptic membrane organization (GO:0097090) | 3.90967075 |
| 28 | glycerophospholipid catabolic process (GO:0046475) | 3.90852995 |
| 29 | retinal cone cell development (GO:0046549) | 3.86699376 |
| 30 | centriole assembly (GO:0098534) | 3.78501855 |
| 31 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.77188535 |
| 32 | cilium movement (GO:0003341) | 3.76931315 |
| 33 | neurotransmitter uptake (GO:0001504) | 3.73587410 |
| 34 | diterpenoid biosynthetic process (GO:0016102) | 3.73566748 |
| 35 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.73185540 |
| 36 | eye photoreceptor cell differentiation (GO:0001754) | 3.72416335 |
| 37 | photoreceptor cell differentiation (GO:0046530) | 3.72416335 |
| 38 | presynaptic membrane assembly (GO:0097105) | 3.65661225 |
| 39 | axonemal dynein complex assembly (GO:0070286) | 3.59672151 |
| 40 | photoreceptor cell maintenance (GO:0045494) | 3.53886093 |
| 41 | exogenous drug catabolic process (GO:0042738) | 3.49469895 |
| 42 | primary alcohol catabolic process (GO:0034310) | 3.45703682 |
| 43 | limb bud formation (GO:0060174) | 3.44781651 |
| 44 | response to redox state (GO:0051775) | 3.43541259 |
| 45 | GPI anchor biosynthetic process (GO:0006506) | 3.42988184 |
| 46 | cell projection assembly (GO:0030031) | 3.40633856 |
| 47 | response to xenobiotic stimulus (GO:0009410) | 3.40468274 |
| 48 | indolalkylamine metabolic process (GO:0006586) | 3.37097229 |
| 49 | amino acid import (GO:0043090) | 3.34266845 |
| 50 | neural tube formation (GO:0001841) | 3.31165444 |
| 51 | response to pheromone (GO:0019236) | 3.24373874 |
| 52 | L-fucose catabolic process (GO:0042355) | 3.24005049 |
| 53 | fucose catabolic process (GO:0019317) | 3.24005049 |
| 54 | L-fucose metabolic process (GO:0042354) | 3.24005049 |
| 55 | establishment of mitochondrion localization (GO:0051654) | 3.23860650 |
| 56 | GPI anchor metabolic process (GO:0006505) | 3.23836659 |
| 57 | axoneme assembly (GO:0035082) | 3.23261214 |
| 58 | regulation of collateral sprouting (GO:0048670) | 3.23193790 |
| 59 | nucleotide transmembrane transport (GO:1901679) | 3.22806810 |
| 60 | protein neddylation (GO:0045116) | 3.18576857 |
| 61 | drug catabolic process (GO:0042737) | 3.17546873 |
| 62 | isoprenoid biosynthetic process (GO:0008299) | 3.15664354 |
| 63 | microtubule-based movement (GO:0007018) | 3.15586653 |
| 64 | regulation of germinal center formation (GO:0002634) | 3.15194987 |
| 65 | response to methylmercury (GO:0051597) | 3.15010055 |
| 66 | retinal rod cell development (GO:0046548) | 3.12885204 |
| 67 | one-carbon compound transport (GO:0019755) | 3.12827608 |
| 68 | amyloid precursor protein metabolic process (GO:0042982) | 3.12081469 |
| 69 | terpenoid biosynthetic process (GO:0016114) | 3.09655305 |
| 70 | ethanol metabolic process (GO:0006067) | 3.04060741 |
| 71 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.03611568 |
| 72 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.02097648 |
| 73 | indole-containing compound catabolic process (GO:0042436) | 3.01950995 |
| 74 | indolalkylamine catabolic process (GO:0046218) | 3.01950995 |
| 75 | tryptophan catabolic process (GO:0006569) | 3.01950995 |
| 76 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.01067437 |
| 77 | protein palmitoylation (GO:0018345) | 2.99136422 |
| 78 | vitamin transmembrane transport (GO:0035461) | 2.98330763 |
| 79 | serotonin metabolic process (GO:0042428) | 2.98111348 |
| 80 | sperm motility (GO:0030317) | 2.97007908 |
| 81 | cholesterol biosynthetic process (GO:0006695) | 2.96952804 |
| 82 | negative regulation of chemokine production (GO:0032682) | 2.95548995 |
| 83 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.94039495 |
| 84 | astrocyte development (GO:0014002) | 2.93551489 |
| 85 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.92037775 |
| 86 | determination of left/right symmetry (GO:0007368) | 2.90692877 |
| 87 | brain morphogenesis (GO:0048854) | 2.88638459 |
| 88 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.87207948 |
| 89 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.87129197 |
| 90 | negative regulation of B cell mediated immunity (GO:0002713) | 2.87129197 |
| 91 | protein polyglutamylation (GO:0018095) | 2.86941197 |
| 92 | lateral ventricle development (GO:0021670) | 2.86424514 |
| 93 | cornea development in camera-type eye (GO:0061303) | 2.85787687 |
| 94 | smoothened signaling pathway (GO:0007224) | 2.84513931 |
| 95 | neuron remodeling (GO:0016322) | 2.80695625 |
| 96 | regulation of lipoprotein metabolic process (GO:0050746) | 2.79698343 |
| 97 | cranial nerve development (GO:0021545) | 2.79086910 |
| 98 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.78834950 |
| 99 | negative regulation of myoblast differentiation (GO:0045662) | 2.77836734 |
| 100 | benzene-containing compound metabolic process (GO:0042537) | 2.75333004 |
| 101 | detection of light stimulus involved in visual perception (GO:0050908) | 2.73998603 |
| 102 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.73998603 |
| 103 | determination of bilateral symmetry (GO:0009855) | 2.73002560 |
| 104 | primary amino compound metabolic process (GO:1901160) | 2.72830318 |
| 105 | magnesium ion transport (GO:0015693) | 2.71747334 |
| 106 | apical protein localization (GO:0045176) | 2.71564522 |
| 107 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.70819552 |
| 108 | retinoic acid metabolic process (GO:0042573) | 2.70415069 |
| 109 | mannosylation (GO:0097502) | 2.70183404 |
| 110 | positive regulation of action potential (GO:0045760) | 2.70128732 |
| 111 | response to lipoprotein particle (GO:0055094) | 2.69587843 |
| 112 | cellular ketone body metabolic process (GO:0046950) | 2.67551501 |
| 113 | asymmetric protein localization (GO:0008105) | 2.67506771 |
| 114 | positive regulation of steroid hormone secretion (GO:2000833) | 2.67366740 |
| 115 | reactive oxygen species biosynthetic process (GO:1903409) | 2.65840118 |
| 116 | kynurenine metabolic process (GO:0070189) | 2.65801970 |
| 117 | indole-containing compound metabolic process (GO:0042430) | 2.65328319 |
| 118 | superoxide anion generation (GO:0042554) | 2.63782622 |
| 119 | specification of symmetry (GO:0009799) | 2.63771319 |
| 120 | sterol biosynthetic process (GO:0016126) | 2.63473237 |
| 121 | enteric nervous system development (GO:0048484) | 2.62553405 |
| 122 | tryptophan metabolic process (GO:0006568) | 2.61496300 |
| 123 | mechanosensory behavior (GO:0007638) | 2.60495321 |
| 124 | regulation of pigment cell differentiation (GO:0050932) | 2.59268334 |
| 125 | membrane tubulation (GO:0097320) | 2.59260630 |
| 126 | neuronal action potential (GO:0019228) | 2.59210220 |
| 127 | epithelial cilium movement (GO:0003351) | 2.58138793 |
| 128 | negative regulation of exocytosis (GO:0045920) | 2.55533864 |
| 129 | glycosylceramide metabolic process (GO:0006677) | 2.53789234 |
| 130 | adult walking behavior (GO:0007628) | 2.53236292 |
| 131 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.52956748 |
| 132 | tolerance induction (GO:0002507) | 2.52427119 |
| 133 | positive regulation of cellular amine metabolic process (GO:0033240) | 2.52159987 |
| 134 | developmental pigmentation (GO:0048066) | 2.52146100 |
| 135 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.49489613 |
| 136 | cellular response to gamma radiation (GO:0071480) | 2.48819587 |
| 137 | positive regulation of growth hormone secretion (GO:0060124) | 2.48512260 |
| 138 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 2.48360299 |
| 139 | negative regulation of humoral immune response (GO:0002921) | 2.48063612 |
| 140 | spinal cord motor neuron differentiation (GO:0021522) | 2.47603316 |
| 141 | adult feeding behavior (GO:0008343) | 2.47584835 |
| 142 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.47396341 |
| 143 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.47110695 |
| 144 | negative regulation of telomere maintenance (GO:0032205) | 2.46564777 |
| 145 | creatine metabolic process (GO:0006600) | 2.44759351 |
| 146 | glycolipid biosynthetic process (GO:0009247) | 2.43964920 |
| 147 | neurotransmitter metabolic process (GO:0042133) | 2.43127144 |
| 148 | auditory behavior (GO:0031223) | 2.42660424 |
| 149 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.40762997 |
| 150 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.40678490 |
| 151 | neutrophil activation involved in immune response (GO:0002283) | 2.39978296 |
| 152 | photoreceptor cell development (GO:0042461) | 2.39439362 |
| 153 | axon development (GO:0061564) | 2.39155056 |
| 154 | neuron cell-cell adhesion (GO:0007158) | 2.37930851 |
| 155 | ketone body metabolic process (GO:1902224) | 2.36999431 |
| 156 | sialylation (GO:0097503) | 2.36884235 |
| 157 | phosphatidylethanolamine metabolic process (GO:0046337) | 2.36714189 |
| 158 | centriole replication (GO:0007099) | 2.34978654 |
| 159 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 2.34695343 |
| 160 | embryonic epithelial tube formation (GO:0001838) | 2.34622489 |
| 161 | myelination in peripheral nervous system (GO:0022011) | 2.34566453 |
| 162 | peripheral nervous system axon ensheathment (GO:0032292) | 2.34566453 |
| 163 | phenol-containing compound catabolic process (GO:0019336) | 2.34509942 |
| 164 | organ growth (GO:0035265) | 2.33882584 |
| 165 | amyloid precursor protein catabolic process (GO:0042987) | 2.33808816 |
| 166 | thyroid hormone metabolic process (GO:0042403) | 2.32330573 |
| 167 | amine catabolic process (GO:0009310) | 2.31531006 |
| 168 | cellular biogenic amine catabolic process (GO:0042402) | 2.31531006 |
| 169 | neurotransmitter catabolic process (GO:0042135) | 2.30659213 |
| 170 | negative regulation of JUN kinase activity (GO:0043508) | 2.30245721 |
| 171 | microtubule depolymerization (GO:0007019) | 2.30225938 |
| 172 | regulation of feeding behavior (GO:0060259) | 2.30175882 |
| 173 | glutathione derivative metabolic process (GO:1901685) | 2.29634735 |
| 174 | negative regulation of acute inflammatory response (GO:0002674) | 2.27659965 |
| 175 | startle response (GO:0001964) | 2.27416106 |
| 176 | polyol transport (GO:0015791) | 2.26621387 |
| 177 | microtubule polymerization or depolymerization (GO:0031109) | 2.26065374 |
| 178 | response to epinephrine (GO:0071871) | 2.25497561 |
| 179 | peripheral nervous system development (GO:0007422) | 2.24422200 |
| 180 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 2.24242690 |
| 181 | glial cell development (GO:0021782) | 2.23624119 |
| 182 | positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) | 2.23328512 |
| 183 | regulation of pseudopodium assembly (GO:0031272) | 2.23057660 |
| 184 | nonmotile primary cilium assembly (GO:0035058) | 2.21870145 |
| 185 | neuronal action potential propagation (GO:0019227) | 2.21705348 |
| 186 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.21095215 |
| 187 | positive regulation of glial cell differentiation (GO:0045687) | 2.20130476 |
| 188 | positive regulation of cell fate commitment (GO:0010455) | 2.20086650 |
| 189 | axon ensheathment in central nervous system (GO:0032291) | 11.0314632 |
| 190 | central nervous system myelination (GO:0022010) | 11.0314632 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.62902044 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.12105978 |
| 3 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.65638662 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.52760089 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.31929085 |
| 6 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.30451756 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.25299826 |
| 8 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.13788529 |
| 9 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.05308576 |
| 10 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.03979718 |
| 11 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 2.02504233 |
| 12 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.00848578 |
| 13 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.97530774 |
| 14 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.95559075 |
| 15 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.95072192 |
| 16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.94703990 |
| 17 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.91796117 |
| 18 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.91609369 |
| 19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.90709141 |
| 20 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.88831707 |
| 21 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.87219105 |
| 22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.86803929 |
| 23 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.84863193 |
| 24 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.83937387 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.83212016 |
| 26 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.80597933 |
| 27 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.78438445 |
| 28 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.76607001 |
| 29 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.71786963 |
| 30 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.71786963 |
| 31 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.71476036 |
| 32 | VDR_22108803_ChIP-Seq_LS180_Human | 1.70488352 |
| 33 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.70073757 |
| 34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.69787833 |
| 35 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.69606954 |
| 36 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.69048771 |
| 37 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.68381434 |
| 38 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.67709642 |
| 39 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.65840897 |
| 40 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.65304708 |
| 41 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.62333898 |
| 42 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.61909982 |
| 43 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.60520293 |
| 44 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.60390209 |
| 45 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.58625924 |
| 46 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58501207 |
| 47 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.58390572 |
| 48 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.58028899 |
| 49 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.57330917 |
| 50 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.57180149 |
| 51 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.56756972 |
| 52 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.56609949 |
| 53 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.56609949 |
| 54 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.56291750 |
| 55 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.56277474 |
| 56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.55840181 |
| 57 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.55840181 |
| 58 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.55772322 |
| 59 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.55526896 |
| 60 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.51078871 |
| 61 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.50827380 |
| 62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.50671399 |
| 63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.50392719 |
| 64 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.49800087 |
| 65 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.49677654 |
| 66 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.49269418 |
| 67 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.48137542 |
| 68 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.48079391 |
| 69 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.47743316 |
| 70 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.46691908 |
| 71 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.45758298 |
| 72 | FUS_26573619_Chip-Seq_HEK293_Human | 1.42330020 |
| 73 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.42015892 |
| 74 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.39612062 |
| 75 | AR_25329375_ChIP-Seq_VCAP_Human | 1.39480370 |
| 76 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.39243271 |
| 77 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.39007211 |
| 78 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.38922202 |
| 79 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.38675665 |
| 80 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.38238283 |
| 81 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.36488254 |
| 82 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.34883911 |
| 83 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.34216464 |
| 84 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.33844798 |
| 85 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.33844798 |
| 86 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.33365843 |
| 87 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.33149952 |
| 88 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.32197248 |
| 89 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29524681 |
| 90 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29524681 |
| 91 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.29318169 |
| 92 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.27906693 |
| 93 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.26669373 |
| 94 | STAT3_23295773_ChIP-Seq_U87_Human | 1.25830919 |
| 95 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25686818 |
| 96 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.25619563 |
| 97 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.25601116 |
| 98 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.25505769 |
| 99 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.24816737 |
| 100 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.24568823 |
| 101 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.24436417 |
| 102 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.24185594 |
| 103 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.24103190 |
| 104 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.23656500 |
| 105 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.23445422 |
| 106 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.23375119 |
| 107 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.22607595 |
| 108 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.22395893 |
| 109 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.21413282 |
| 110 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.21338530 |
| 111 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.21030176 |
| 112 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20024601 |
| 113 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.19725676 |
| 114 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.19684395 |
| 115 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.19503244 |
| 116 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18813022 |
| 117 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.18575352 |
| 118 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.18434296 |
| 119 | AR_20517297_ChIP-Seq_VCAP_Human | 1.18205270 |
| 120 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.17674562 |
| 121 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.17021267 |
| 122 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.15901007 |
| 123 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.15586717 |
| 124 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.15216324 |
| 125 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.14296687 |
| 126 | KDM2B_26808549_Chip-Seq_REH_Human | 1.14183405 |
| 127 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.13402070 |
| 128 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.12277380 |
| 129 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12220809 |
| 130 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12006359 |
| 131 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11927015 |
| 132 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.11771277 |
| 133 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.11757454 |
| 134 | TCF4_23295773_ChIP-Seq_U87_Human | 1.11333351 |
| 135 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11076450 |
| 136 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.10955999 |
| 137 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.09685319 |
| 138 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.06371982 |
| 139 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.05564580 |
| 140 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.05499409 |
| 141 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.03627456 |
| 142 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.02469267 |
| 143 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.01433792 |
| 144 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.99492438 |
| 145 | TBL1_22424771_ChIP-Seq_293T_Human | 0.99282146 |
| 146 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.98597899 |
| 147 | TP53_16413492_ChIP-PET_HCT116_Human | 0.98463353 |
| 148 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.97721517 |
| 149 | NFYA_21822215_ChIP-Seq_K562_Human | 0.97482598 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002653_abnormal_ependyma_morphology | 4.27897819 |
| 2 | MP0000920_abnormal_myelination | 4.18436737 |
| 3 | MP0008875_abnormal_xenobiotic_pharmacok | 4.13220719 |
| 4 | MP0003136_yellow_coat_color | 4.06876297 |
| 5 | MP0005171_absent_coat_pigmentation | 3.52090386 |
| 6 | MP0003880_abnormal_central_pattern | 3.27090113 |
| 7 | MP0004381_abnormal_hair_follicle | 2.98181477 |
| 8 | MP0004742_abnormal_vestibular_system | 2.87547505 |
| 9 | MP0005409_darkened_coat_color | 2.85333093 |
| 10 | MP0001984_abnormal_olfaction | 2.68421331 |
| 11 | MP0000569_abnormal_digit_pigmentation | 2.63949245 |
| 12 | MP0003690_abnormal_glial_cell | 2.62024782 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.53204423 |
| 14 | MP0003950_abnormal_plasma_membrane | 2.47183188 |
| 15 | MP0001486_abnormal_startle_reflex | 2.40016444 |
| 16 | MP0001905_abnormal_dopamine_level | 2.28284977 |
| 17 | MP0001501_abnormal_sleep_pattern | 2.22658607 |
| 18 | MP0002272_abnormal_nervous_system | 2.16166344 |
| 19 | MP0005646_abnormal_pituitary_gland | 2.09742232 |
| 20 | MP0001188_hyperpigmentation | 1.99513642 |
| 21 | MP0000566_synostosis | 1.99293531 |
| 22 | MP0004142_abnormal_muscle_tone | 1.95283570 |
| 23 | MP0008872_abnormal_physiological_respon | 1.94177600 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.93361434 |
| 25 | MP0001529_abnormal_vocalization | 1.92365958 |
| 26 | MP0004270_analgesia | 1.89333287 |
| 27 | MP0003787_abnormal_imprinting | 1.82502042 |
| 28 | MP0009046_muscle_twitch | 1.73197349 |
| 29 | MP0002064_seizures | 1.70938348 |
| 30 | MP0005451_abnormal_body_composition | 1.68753265 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.66133166 |
| 32 | MP0003634_abnormal_glial_cell | 1.64574655 |
| 33 | MP0005410_abnormal_fertilization | 1.64429315 |
| 34 | MP0002102_abnormal_ear_morphology | 1.61902250 |
| 35 | MP0000427_abnormal_hair_cycle | 1.60854363 |
| 36 | MP0005423_abnormal_somatic_nervous | 1.59553577 |
| 37 | MP0001485_abnormal_pinna_reflex | 1.59366005 |
| 38 | MP0002909_abnormal_adrenal_gland | 1.58417834 |
| 39 | MP0001963_abnormal_hearing_physiology | 1.58233269 |
| 40 | MP0009745_abnormal_behavioral_response | 1.56276592 |
| 41 | MP0000778_abnormal_nervous_system | 1.55755811 |
| 42 | MP0004147_increased_porphyrin_level | 1.54271950 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.52790311 |
| 44 | MP0002735_abnormal_chemical_nociception | 1.52424007 |
| 45 | MP0002160_abnormal_reproductive_system | 1.50353972 |
| 46 | MP0002734_abnormal_mechanical_nocicepti | 1.49609255 |
| 47 | MP0008789_abnormal_olfactory_epithelium | 1.48296312 |
| 48 | MP0000026_abnormal_inner_ear | 1.44482733 |
| 49 | MP0010386_abnormal_urinary_bladder | 1.43166198 |
| 50 | MP0004885_abnormal_endolymph | 1.40492603 |
| 51 | MP0008260_abnormal_autophagy | 1.37399671 |
| 52 | MP0004134_abnormal_chest_morphology | 1.37263074 |
| 53 | MP0006292_abnormal_olfactory_placode | 1.33679330 |
| 54 | MP0005377_hearing/vestibular/ear_phenot | 1.33620194 |
| 55 | MP0003878_abnormal_ear_physiology | 1.33620194 |
| 56 | MP0005083_abnormal_biliary_tract | 1.32669090 |
| 57 | MP0001346_abnormal_lacrimal_gland | 1.32177438 |
| 58 | MP0002229_neurodegeneration | 1.32114069 |
| 59 | MP0005389_reproductive_system_phenotype | 1.31256631 |
| 60 | MP0004019_abnormal_vitamin_homeostasis | 1.30443539 |
| 61 | MP0009780_abnormal_chondrocyte_physiolo | 1.28796226 |
| 62 | MP0001502_abnormal_circadian_rhythm | 1.28036750 |
| 63 | MP0002928_abnormal_bile_duct | 1.27926618 |
| 64 | MP0006072_abnormal_retinal_apoptosis | 1.27509587 |
| 65 | MP0001986_abnormal_taste_sensitivity | 1.26775802 |
| 66 | MP0002572_abnormal_emotion/affect_behav | 1.24802990 |
| 67 | MP0001440_abnormal_grooming_behavior | 1.23271380 |
| 68 | MP0006082_CNS_inflammation | 1.21550301 |
| 69 | MP0003632_abnormal_nervous_system | 1.20322891 |
| 70 | MP0005174_abnormal_tail_pigmentation | 1.19384551 |
| 71 | MP0002938_white_spotting | 1.19268639 |
| 72 | MP0003329_amyloid_beta_deposits | 1.18158184 |
| 73 | MP0005623_abnormal_meninges_morphology | 1.17822705 |
| 74 | MP0004043_abnormal_pH_regulation | 1.16378038 |
| 75 | MP0005167_abnormal_blood-brain_barrier | 1.16118951 |
| 76 | MP0001970_abnormal_pain_threshold | 1.16040982 |
| 77 | MP0002067_abnormal_sensory_capabilities | 1.15762437 |
| 78 | MP0003631_nervous_system_phenotype | 1.13382110 |
| 79 | MP0003938_abnormal_ear_development | 1.12678075 |
| 80 | MP0003724_increased_susceptibility_to | 1.12125852 |
| 81 | MP0002752_abnormal_somatic_nervous | 1.12113921 |
| 82 | MP0003718_maternal_effect | 1.11552886 |
| 83 | MP0003635_abnormal_synaptic_transmissio | 1.11472040 |
| 84 | MP0005645_abnormal_hypothalamus_physiol | 1.11243967 |
| 85 | MP0003252_abnormal_bile_duct | 1.09988194 |
| 86 | MP0000383_abnormal_hair_follicle | 1.09965811 |
| 87 | MP0005085_abnormal_gallbladder_physiolo | 1.09611916 |
| 88 | MP0002837_dystrophic_cardiac_calcinosis | 1.09537874 |
| 89 | MP0002148_abnormal_hypersensitivity_rea | 1.08449888 |
| 90 | MP0005075_abnormal_melanosome_morpholog | 1.08285833 |
| 91 | MP0005379_endocrine/exocrine_gland_phen | 1.07952881 |
| 92 | MP0002876_abnormal_thyroid_physiology | 1.07833658 |
| 93 | MP0001765_abnormal_ion_homeostasis | 1.05204848 |
| 94 | MP0001968_abnormal_touch/_nociception | 1.04596571 |
| 95 | MP0003698_abnormal_male_reproductive | 1.04469993 |
| 96 | MP0000762_abnormal_tongue_morphology | 1.02366252 |
| 97 | MP0002277_abnormal_respiratory_mucosa | 1.00662218 |
| 98 | MP0002882_abnormal_neuron_morphology | 1.00029253 |
| 99 | MP0004133_heterotaxia | 0.98604558 |
| 100 | MP0002168_other_aberrant_phenotype | 0.98526716 |
| 101 | MP0003937_abnormal_limbs/digits/tail_de | 0.98494585 |
| 102 | MP0002736_abnormal_nociception_after | 0.98281201 |
| 103 | MP0003633_abnormal_nervous_system | 0.98275060 |
| 104 | MP0004782_abnormal_surfactant_physiolog | 0.98017539 |
| 105 | MP0005084_abnormal_gallbladder_morpholo | 0.97741178 |
| 106 | MP0001177_atelectasis | 0.97724660 |
| 107 | MP0001929_abnormal_gametogenesis | 0.97484908 |
| 108 | MP0005195_abnormal_posterior_eye | 0.96724511 |
| 109 | MP0009250_abnormal_appendicular_skeleto | 0.96491685 |
| 110 | MP0002638_abnormal_pupillary_reflex | 0.96316262 |
| 111 | MP0001324_abnormal_eye_pigmentation | 0.95235205 |
| 112 | MP0005253_abnormal_eye_physiology | 0.93887127 |
| 113 | MP0002163_abnormal_gland_morphology | 0.93010997 |
| 114 | MP0003011_delayed_dark_adaptation | 0.92736189 |
| 115 | MP0010678_abnormal_skin_adnexa | 0.91997730 |
| 116 | MP0002063_abnormal_learning/memory/cond | 0.91949946 |
| 117 | MP0005395_other_phenotype | 0.89931875 |
| 118 | MP0008569_lethality_at_weaning | 0.89233602 |
| 119 | MP0000955_abnormal_spinal_cord | 0.87856963 |
| 120 | MP0000015_abnormal_ear_pigmentation | 0.86913600 |
| 121 | MP0004859_abnormal_synaptic_plasticity | 0.85007028 |
| 122 | MP0002066_abnormal_motor_capabilities/c | 0.83780960 |
| 123 | MP0005636_abnormal_mineral_homeostasis | 0.81196700 |
| 124 | MP0008775_abnormal_heart_ventricle | 0.79565959 |
| 125 | MP0003646_muscle_fatigue | 0.79128478 |
| 126 | MP0004924_abnormal_behavior | 0.78283049 |
| 127 | MP0005386_behavior/neurological_phenoty | 0.78283049 |
| 128 | MP0000462_abnormal_digestive_system | 0.77974691 |
| 129 | MP0002933_joint_inflammation | 0.77791171 |
| 130 | MP0001790_abnormal_immune_system | 0.77221700 |
| 131 | MP0005387_immune_system_phenotype | 0.77221700 |
| 132 | MP0000230_abnormal_systemic_arterial | 0.76877772 |
| 133 | MP0002282_abnormal_trachea_morphology | 0.76277803 |
| 134 | MP0003195_calcinosis | 0.76263591 |
| 135 | MP0005388_respiratory_system_phenotype | 0.76132828 |
| 136 | MP0002133_abnormal_respiratory_system | 0.76132828 |
| 137 | MP0000631_abnormal_neuroendocrine_gland | 0.74797098 |
| 138 | MP0005394_taste/olfaction_phenotype | 0.74654364 |
| 139 | MP0005499_abnormal_olfactory_system | 0.74654364 |
| 140 | MP0005266_abnormal_metabolism | 0.74631714 |
| 141 | MP0001664_abnormal_digestion | 0.73976562 |
| 142 | MP0002557_abnormal_social/conspecific_i | 0.73625908 |
| 143 | MP0002249_abnormal_larynx_morphology | 0.72362157 |
| 144 | MP0001851_eye_inflammation | 0.71339662 |
| 145 | MP0002733_abnormal_thermal_nociception | 0.71090018 |
| 146 | MP0002693_abnormal_pancreas_physiology | 0.71073326 |
| 147 | MP0005310_abnormal_salivary_gland | 0.70984001 |
| 148 | MP0001919_abnormal_reproductive_system | 0.70804178 |
| 149 | MP0002132_abnormal_respiratory_system | 0.69922228 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal ciliary motility (HP:0012262) | 6.42980111 |
| 2 | Chronic bronchitis (HP:0004469) | 5.70935994 |
| 3 | Abnormal respiratory motile cilium physiology (HP:0012261) | 5.53239499 |
| 4 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.92872347 |
| 5 | Abnormal respiratory epithelium morphology (HP:0012253) | 4.74757180 |
| 6 | Abnormal respiratory motile cilium morphology (HP:0005938) | 4.74757180 |
| 7 | Pancreatic fibrosis (HP:0100732) | 4.59689937 |
| 8 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.48744705 |
| 9 | Absent/shortened dynein arms (HP:0200106) | 4.48744705 |
| 10 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 4.41656651 |
| 11 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 4.41656651 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 4.38465593 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 4.38465593 |
| 14 | Pancreatic cysts (HP:0001737) | 4.37270708 |
| 15 | Parakeratosis (HP:0001036) | 4.28451531 |
| 16 | Nasal polyposis (HP:0100582) | 3.86355868 |
| 17 | Rhinitis (HP:0012384) | 3.69532161 |
| 18 | Chronic hepatic failure (HP:0100626) | 3.68010491 |
| 19 | Abnormality of the renal medulla (HP:0100957) | 3.66946530 |
| 20 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.46162080 |
| 21 | Septo-optic dysplasia (HP:0100842) | 3.40995169 |
| 22 | Peripheral hypomyelination (HP:0007182) | 3.38205129 |
| 23 | White forelock (HP:0002211) | 3.31898093 |
| 24 | Cystic liver disease (HP:0006706) | 3.31190377 |
| 25 | Neurofibrillary tangles (HP:0002185) | 3.30033583 |
| 26 | Patchy hypopigmentation of hair (HP:0011365) | 3.29586070 |
| 27 | Bronchitis (HP:0012387) | 3.29504086 |
| 28 | Occipital encephalocele (HP:0002085) | 3.28098230 |
| 29 | Chronic sinusitis (HP:0011109) | 3.26664769 |
| 30 | Absent septum pellucidum (HP:0001331) | 3.12589250 |
| 31 | Abnormality of the nasal mucosa (HP:0000433) | 2.98442062 |
| 32 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.91935888 |
| 33 | Onion bulb formation (HP:0003383) | 2.91681658 |
| 34 | Tubular atrophy (HP:0000092) | 2.91205204 |
| 35 | Infertility (HP:0000789) | 2.89536805 |
| 36 | Abnormality of the corticospinal tract (HP:0002492) | 2.87793809 |
| 37 | Abnormality of the septum pellucidum (HP:0007375) | 2.79910694 |
| 38 | Abnormality of the renal cortex (HP:0011035) | 2.76898062 |
| 39 | Postaxial foot polydactyly (HP:0001830) | 2.72667975 |
| 40 | Congenital hepatic fibrosis (HP:0002612) | 2.72021172 |
| 41 | Duplicated collecting system (HP:0000081) | 2.65229769 |
| 42 | Sensory axonal neuropathy (HP:0003390) | 2.64223322 |
| 43 | Abnormal auditory evoked potentials (HP:0006958) | 2.61517327 |
| 44 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.56400626 |
| 45 | Abnormality of the renal collecting system (HP:0004742) | 2.47608280 |
| 46 | Anencephaly (HP:0002323) | 2.45491816 |
| 47 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.44124562 |
| 48 | Abnormal drinking behavior (HP:0030082) | 2.43146500 |
| 49 | Polydipsia (HP:0001959) | 2.43146500 |
| 50 | Decreased circulating renin level (HP:0003351) | 2.41028913 |
| 51 | Male pseudohermaphroditism (HP:0000037) | 2.37941214 |
| 52 | Sclerocornea (HP:0000647) | 2.37394320 |
| 53 | Abnormal hair whorl (HP:0010721) | 2.36779501 |
| 54 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.36333480 |
| 55 | Hypoplasia of the iris (HP:0007676) | 2.34400175 |
| 56 | Morphological abnormality of the inner ear (HP:0011390) | 2.34171798 |
| 57 | Recurrent otitis media (HP:0000403) | 2.33744156 |
| 58 | Retinal dysplasia (HP:0007973) | 2.33217920 |
| 59 | Tubulointerstitial abnormality (HP:0001969) | 2.32328683 |
| 60 | Hyperactive renin-angiotensin system (HP:0000841) | 2.29336564 |
| 61 | Alacrima (HP:0000522) | 2.28329610 |
| 62 | Metabolic alkalosis (HP:0200114) | 2.26212874 |
| 63 | 3-Methylglutaconic aciduria (HP:0003535) | 2.25117534 |
| 64 | Prolonged neonatal jaundice (HP:0006579) | 2.24741024 |
| 65 | Chronic otitis media (HP:0000389) | 2.24327248 |
| 66 | Furrowed tongue (HP:0000221) | 2.23561167 |
| 67 | Hypomagnesemia (HP:0002917) | 2.20034905 |
| 68 | Abnormality of molar (HP:0011077) | 2.18731815 |
| 69 | Abnormality of molar morphology (HP:0011070) | 2.18731815 |
| 70 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.18037471 |
| 71 | Renal Fanconi syndrome (HP:0001994) | 2.15402146 |
| 72 | Male infertility (HP:0003251) | 2.10934355 |
| 73 | Conical tooth (HP:0000698) | 2.08928312 |
| 74 | Hypophosphatemic rickets (HP:0004912) | 2.08712386 |
| 75 | Thickened helices (HP:0000391) | 2.08045612 |
| 76 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.03138512 |
| 77 | Congenital sensorineural hearing impairment (HP:0008527) | 2.01278741 |
| 78 | Medial flaring of the eyebrow (HP:0010747) | 2.01141680 |
| 79 | Vaginal atresia (HP:0000148) | 2.01030884 |
| 80 | Postaxial hand polydactyly (HP:0001162) | 2.00832549 |
| 81 | Anteriorly placed anus (HP:0001545) | 2.00057701 |
| 82 | Asplenia (HP:0001746) | 1.99485129 |
| 83 | Abnormality of permanent molar morphology (HP:0011071) | 1.98352471 |
| 84 | Abnormality of the dental root (HP:0006486) | 1.98352471 |
| 85 | Taurodontia (HP:0000679) | 1.98352471 |
| 86 | Congenital stationary night blindness (HP:0007642) | 1.97362258 |
| 87 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.95840321 |
| 88 | Genital tract atresia (HP:0001827) | 1.95262673 |
| 89 | Submucous cleft hard palate (HP:0000176) | 1.94455633 |
| 90 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.94017410 |
| 91 | Oculomotor apraxia (HP:0000657) | 1.93514906 |
| 92 | Myokymia (HP:0002411) | 1.93458545 |
| 93 | Polyuria (HP:0000103) | 1.93448407 |
| 94 | Hepatosplenomegaly (HP:0001433) | 1.91461275 |
| 95 | Optic nerve hypoplasia (HP:0000609) | 1.90825225 |
| 96 | Tubulointerstitial nephritis (HP:0001970) | 1.90263836 |
| 97 | Abnormality of incisor morphology (HP:0011063) | 1.89498951 |
| 98 | Anomalous pulmonary venous return (HP:0010772) | 1.89381210 |
| 99 | Bronchiectasis (HP:0002110) | 1.89172164 |
| 100 | Hypothermia (HP:0002045) | 1.88581986 |
| 101 | Leukodystrophy (HP:0002415) | 1.88165971 |
| 102 | Tubulointerstitial fibrosis (HP:0005576) | 1.88149706 |
| 103 | Adrenal hypoplasia (HP:0000835) | 1.87776247 |
| 104 | Focal motor seizures (HP:0011153) | 1.87117218 |
| 105 | Recurrent sinusitis (HP:0011108) | 1.86899405 |
| 106 | Stridor (HP:0010307) | 1.86215916 |
| 107 | Split foot (HP:0001839) | 1.85853735 |
| 108 | Abnormality of the dental pulp (HP:0006479) | 1.85630153 |
| 109 | True hermaphroditism (HP:0010459) | 1.85151093 |
| 110 | Poor coordination (HP:0002370) | 1.85082457 |
| 111 | Supranuclear gaze palsy (HP:0000605) | 1.84314796 |
| 112 | Attenuation of retinal blood vessels (HP:0007843) | 1.82002678 |
| 113 | Gait imbalance (HP:0002141) | 1.80971638 |
| 114 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.80537583 |
| 115 | Scanning speech (HP:0002168) | 1.79650982 |
| 116 | Hypokalemic alkalosis (HP:0001949) | 1.79398268 |
| 117 | Stomach cancer (HP:0012126) | 1.78058178 |
| 118 | Decreased lacrimation (HP:0000633) | 1.77774604 |
| 119 | Clumsiness (HP:0002312) | 1.77734983 |
| 120 | Nephropathy (HP:0000112) | 1.77545915 |
| 121 | Abolished electroretinogram (ERG) (HP:0000550) | 1.77357355 |
| 122 | Renal salt wasting (HP:0000127) | 1.77043535 |
| 123 | Cerebral inclusion bodies (HP:0100314) | 1.76444075 |
| 124 | Aplasia cutis congenita (HP:0001057) | 1.76274815 |
| 125 | Stage 5 chronic kidney disease (HP:0003774) | 1.75320328 |
| 126 | Absent speech (HP:0001344) | 1.74238401 |
| 127 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.73545991 |
| 128 | Constricted visual fields (HP:0001133) | 1.73506206 |
| 129 | Retinitis pigmentosa (HP:0000510) | 1.73312351 |
| 130 | Hypoplastic pelvis (HP:0008839) | 1.72884812 |
| 131 | Abnormality of dentin (HP:0010299) | 1.71710736 |
| 132 | Spastic gait (HP:0002064) | 1.69706625 |
| 133 | Abnormality of renin-angiotensin system (HP:0000847) | 1.69692764 |
| 134 | Bile duct proliferation (HP:0001408) | 1.66501289 |
| 135 | Abnormal biliary tract physiology (HP:0012439) | 1.66501289 |
| 136 | Cerebral hypomyelination (HP:0006808) | 1.66126549 |
| 137 | Duplication of thumb phalanx (HP:0009942) | 1.64673995 |
| 138 | Stomatitis (HP:0010280) | 1.64628556 |
| 139 | Nasolacrimal duct obstruction (HP:0000579) | 1.64481938 |
| 140 | Hyperkalemia (HP:0002153) | 1.64337927 |
| 141 | Slow saccadic eye movements (HP:0000514) | 1.64102506 |
| 142 | Widely spaced teeth (HP:0000687) | 1.63927231 |
| 143 | Congenital primary aphakia (HP:0007707) | 1.63603309 |
| 144 | Preaxial hand polydactyly (HP:0001177) | 1.63600081 |
| 145 | Recurrent bronchitis (HP:0002837) | 1.63519649 |
| 146 | Decreased central vision (HP:0007663) | 1.63396349 |
| 147 | Nephronophthisis (HP:0000090) | 1.62436146 |
| 148 | Hyperaldosteronism (HP:0000859) | 1.61188869 |
| 149 | Steppage gait (HP:0003376) | 1.60950043 |
| 150 | Hyperventilation (HP:0002883) | 1.60597715 |
| 151 | Cupped ear (HP:0000378) | 1.60078308 |
| 152 | Nephrogenic diabetes insipidus (HP:0009806) | 1.59383086 |
| 153 | Ectopic anus (HP:0004397) | 1.58481004 |
| 154 | Pulmonary artery stenosis (HP:0004415) | 1.57451829 |
| 155 | Abnormality of magnesium homeostasis (HP:0004921) | 1.57111409 |
| 156 | Abnormality of the pulmonary veins (HP:0011718) | 1.57089935 |
| 157 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.56751168 |
| 158 | Abnormality of renal excretion (HP:0011036) | 1.52123743 |
| 159 | Type II lissencephaly (HP:0007260) | 1.50234987 |
| 160 | Abnormal urine output (HP:0012590) | 1.49298654 |
| 161 | Increased corneal curvature (HP:0100692) | 1.48363307 |
| 162 | Keratoconus (HP:0000563) | 1.48363307 |
| 163 | Concave nail (HP:0001598) | 1.47072855 |
| 164 | Prominent nasal bridge (HP:0000426) | 1.45364280 |
| 165 | Gaze-evoked nystagmus (HP:0000640) | 1.45332207 |
| 166 | Abnormality of macular pigmentation (HP:0008002) | 1.43347263 |
| 167 | Supernumerary spleens (HP:0009799) | 1.42940494 |
| 168 | Median cleft lip (HP:0000161) | 1.42062520 |
| 169 | Aganglionic megacolon (HP:0002251) | 1.41040351 |
| 170 | Broad-based gait (HP:0002136) | 1.40300677 |
| 171 | Abnormality of chloride homeostasis (HP:0011422) | 1.39922149 |
| 172 | Narrow forehead (HP:0000341) | 1.36620658 |
| 173 | Pendular nystagmus (HP:0012043) | 1.35967048 |
| 174 | Renal cortical cysts (HP:0000803) | 1.35925483 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.70349389 |
| 2 | STK39 | 4.88175362 |
| 3 | OXSR1 | 3.64075938 |
| 4 | CASK | 3.05005513 |
| 5 | PKN1 | 2.61693443 |
| 6 | PBK | 2.42407858 |
| 7 | MAP4K2 | 2.36959440 |
| 8 | PRPF4B | 2.26258960 |
| 9 | MAPKAPK5 | 2.21023656 |
| 10 | BCR | 2.18176484 |
| 11 | MAPK15 | 2.14862568 |
| 12 | BRD4 | 2.08464840 |
| 13 | EPHB1 | 2.06163694 |
| 14 | ACVR1B | 2.05844348 |
| 15 | MAP3K4 | 2.01065142 |
| 16 | WNK3 | 1.97351227 |
| 17 | MST4 | 1.91734475 |
| 18 | WNK4 | 1.90863653 |
| 19 | CLK1 | 1.88752663 |
| 20 | TAOK3 | 1.87981827 |
| 21 | PTK2B | 1.75367749 |
| 22 | TLK1 | 1.74938332 |
| 23 | NEK6 | 1.62474828 |
| 24 | CDK19 | 1.57414055 |
| 25 | TNIK | 1.53844945 |
| 26 | SGK223 | 1.52822130 |
| 27 | SGK494 | 1.52822130 |
| 28 | GRK7 | 1.52294485 |
| 29 | ADRBK2 | 1.48604927 |
| 30 | MUSK | 1.44968785 |
| 31 | BMPR1B | 1.42808239 |
| 32 | MET | 1.40822643 |
| 33 | YES1 | 1.31952372 |
| 34 | MAP3K14 | 1.31754498 |
| 35 | WNK1 | 1.30994277 |
| 36 | GRK1 | 1.30542939 |
| 37 | CSNK1A1L | 1.30165440 |
| 38 | CAMK2B | 1.29603459 |
| 39 | CAMKK2 | 1.29175642 |
| 40 | MKNK2 | 1.24437384 |
| 41 | TRIM28 | 1.21190053 |
| 42 | MKNK1 | 1.18329164 |
| 43 | CSNK1G3 | 1.17746106 |
| 44 | CAMK2D | 1.15477984 |
| 45 | BMPR2 | 1.14553265 |
| 46 | FGR | 1.13853476 |
| 47 | TIE1 | 1.13463744 |
| 48 | STK38L | 1.12316154 |
| 49 | TXK | 1.10131878 |
| 50 | INSRR | 1.10023777 |
| 51 | DYRK2 | 1.08112269 |
| 52 | NUAK1 | 1.06591230 |
| 53 | MAPKAPK3 | 1.05414341 |
| 54 | NME1 | 1.05380776 |
| 55 | MAP2K7 | 1.01643039 |
| 56 | BLK | 1.01638421 |
| 57 | ADRBK1 | 1.00709398 |
| 58 | CDK3 | 1.00224511 |
| 59 | TRPM7 | 0.99085056 |
| 60 | FGFR2 | 0.98359537 |
| 61 | EPHA4 | 0.98259304 |
| 62 | ROCK2 | 0.97197562 |
| 63 | IRAK4 | 0.93817076 |
| 64 | CSNK1G1 | 0.92509316 |
| 65 | FER | 0.91757202 |
| 66 | STK16 | 0.90429371 |
| 67 | KIT | 0.89872082 |
| 68 | CCNB1 | 0.89743042 |
| 69 | PRKCE | 0.88877595 |
| 70 | NTRK3 | 0.88008284 |
| 71 | PNCK | 0.87341047 |
| 72 | UHMK1 | 0.85693785 |
| 73 | CAMK2A | 0.80127403 |
| 74 | PRKCQ | 0.79942192 |
| 75 | EIF2AK2 | 0.76562387 |
| 76 | LATS1 | 0.76155635 |
| 77 | LIMK1 | 0.74507579 |
| 78 | IRAK2 | 0.74229661 |
| 79 | MAP3K2 | 0.73376563 |
| 80 | MAP3K13 | 0.72886835 |
| 81 | CAMK2G | 0.72875970 |
| 82 | CAMK1G | 0.72837949 |
| 83 | AKT3 | 0.72084045 |
| 84 | IRAK1 | 0.69510990 |
| 85 | PIK3CA | 0.68223923 |
| 86 | ERBB3 | 0.68120019 |
| 87 | TGFBR1 | 0.67790985 |
| 88 | MAPK13 | 0.67514150 |
| 89 | MARK1 | 0.67297431 |
| 90 | GRK6 | 0.66178466 |
| 91 | PRKCI | 0.65942864 |
| 92 | CSNK1G2 | 0.63989639 |
| 93 | GSK3A | 0.63880755 |
| 94 | PRKCG | 0.62458594 |
| 95 | PRKG1 | 0.60959194 |
| 96 | MAP2K4 | 0.60378250 |
| 97 | NTRK2 | 0.58359970 |
| 98 | RPS6KA5 | 0.58300315 |
| 99 | STK3 | 0.58121779 |
| 100 | CAMKK1 | 0.57051880 |
| 101 | ZAK | 0.56583477 |
| 102 | EPHA2 | 0.56130093 |
| 103 | CDK5 | 0.56091885 |
| 104 | MAPK7 | 0.56041563 |
| 105 | CAMK1 | 0.55291759 |
| 106 | PRKCH | 0.55052501 |
| 107 | DAPK2 | 0.54702528 |
| 108 | MAP2K6 | 0.52883437 |
| 109 | NLK | 0.52767681 |
| 110 | PINK1 | 0.51098012 |
| 111 | TAF1 | 0.50901934 |
| 112 | STK24 | 0.50345551 |
| 113 | MAP3K12 | 0.49139940 |
| 114 | MAP3K7 | 0.47190913 |
| 115 | PRKAA2 | 0.46430353 |
| 116 | VRK1 | 0.46308912 |
| 117 | ERBB4 | 0.46070004 |
| 118 | PLK2 | 0.45181411 |
| 119 | SGK2 | 0.43665263 |
| 120 | OBSCN | 0.43526633 |
| 121 | DYRK3 | 0.43177575 |
| 122 | CAMK1D | 0.43171085 |
| 123 | TEC | 0.42813250 |
| 124 | IRAK3 | 0.42668258 |
| 125 | MATK | 0.42412493 |
| 126 | STK11 | 0.42356669 |
| 127 | SGK1 | 0.42065059 |
| 128 | ERBB2 | 0.41293394 |
| 129 | IKBKB | 0.39950551 |
| 130 | PRKD2 | 0.39778524 |
| 131 | TNK2 | 0.38652328 |
| 132 | CSNK1A1 | 0.37640306 |
| 133 | BRSK2 | 0.37179718 |
| 134 | PRKCA | 0.36805294 |
| 135 | PAK3 | 0.36068187 |
| 136 | NTRK1 | 0.35353928 |
| 137 | GRK5 | 0.35341090 |
| 138 | IKBKE | 0.35200953 |
| 139 | PAK6 | 0.34018670 |
| 140 | MAP2K2 | 0.33292675 |
| 141 | PRKACA | 0.32833435 |
| 142 | EPHA3 | 0.31263127 |
| 143 | PHKG2 | 0.29912180 |
| 144 | PHKG1 | 0.29912180 |
| 145 | DYRK1A | 0.29470650 |
| 146 | CSK | 0.29004721 |
| 147 | MAPK12 | 0.28804461 |
| 148 | FYN | 0.28690553 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Steroid biosynthesis_Homo sapiens_hsa00100 | 3.63534096 |
| 2 | Fatty acid elongation_Homo sapiens_hsa00062 | 3.57574760 |
| 3 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.34285007 |
| 4 | Ether lipid metabolism_Homo sapiens_hsa00565 | 3.08044019 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 3.06427119 |
| 6 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.94084952 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.93149703 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.36333044 |
| 9 | Histidine metabolism_Homo sapiens_hsa00340 | 2.14540902 |
| 10 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.07463282 |
| 11 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.03355293 |
| 12 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.97632073 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.96127041 |
| 14 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.91894716 |
| 15 | ABC transporters_Homo sapiens_hsa02010 | 1.80439588 |
| 16 | Phototransduction_Homo sapiens_hsa04744 | 1.72477915 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.71444720 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.71352977 |
| 19 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.70851569 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.70049470 |
| 21 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.68942411 |
| 22 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.68218293 |
| 23 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.66192657 |
| 24 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.64309202 |
| 25 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.61433847 |
| 26 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.61407553 |
| 27 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.54161726 |
| 28 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.52662664 |
| 29 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.48776300 |
| 30 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.43207100 |
| 31 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.36302384 |
| 32 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.36158920 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.34175924 |
| 34 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.33770419 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.31259946 |
| 36 | Nicotine addiction_Homo sapiens_hsa05033 | 1.28576403 |
| 37 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.28006876 |
| 38 | Allograft rejection_Homo sapiens_hsa05330 | 1.25543373 |
| 39 | Morphine addiction_Homo sapiens_hsa05032 | 1.24847453 |
| 40 | GABAergic synapse_Homo sapiens_hsa04727 | 1.23854685 |
| 41 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.20507900 |
| 42 | Axon guidance_Homo sapiens_hsa04360 | 1.19771712 |
| 43 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.19065987 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.17935937 |
| 45 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.16275565 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.13915426 |
| 47 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.11483777 |
| 48 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.10442071 |
| 49 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.06388313 |
| 50 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.05700395 |
| 51 | Protein export_Homo sapiens_hsa03060 | 1.05012972 |
| 52 | Homologous recombination_Homo sapiens_hsa03440 | 1.03427053 |
| 53 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.02503839 |
| 54 | Asthma_Homo sapiens_hsa05310 | 0.96152934 |
| 55 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.94470056 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.94024351 |
| 57 | Alzheimers disease_Homo sapiens_hsa05010 | 0.92338318 |
| 58 | Parkinsons disease_Homo sapiens_hsa05012 | 0.92235781 |
| 59 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.91618889 |
| 60 | Phagosome_Homo sapiens_hsa04145 | 0.90505230 |
| 61 | Malaria_Homo sapiens_hsa05144 | 0.88732456 |
| 62 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.88610294 |
| 63 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.88559458 |
| 64 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.88018348 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.87296501 |
| 66 | Cocaine addiction_Homo sapiens_hsa05030 | 0.84583568 |
| 67 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.83495359 |
| 68 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.83294600 |
| 69 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.80199282 |
| 70 | Mineral absorption_Homo sapiens_hsa04978 | 0.79527878 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.78873770 |
| 72 | Taste transduction_Homo sapiens_hsa04742 | 0.78491760 |
| 73 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.76795472 |
| 74 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.74091190 |
| 75 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.73644526 |
| 76 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72713129 |
| 77 | Long-term depression_Homo sapiens_hsa04730 | 0.72649668 |
| 78 | Huntingtons disease_Homo sapiens_hsa05016 | 0.67439551 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.67031746 |
| 80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.66486618 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.66329980 |
| 82 | Salivary secretion_Homo sapiens_hsa04970 | 0.66276941 |
| 83 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.65002434 |
| 84 | Circadian entrainment_Homo sapiens_hsa04713 | 0.64953518 |
| 85 | Circadian rhythm_Homo sapiens_hsa04710 | 0.64556361 |
| 86 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.63993838 |
| 87 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.63502988 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60945898 |
| 89 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.60076886 |
| 90 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.58066490 |
| 91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57935061 |
| 92 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.57925420 |
| 93 | Insulin secretion_Homo sapiens_hsa04911 | 0.56436768 |
| 94 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.55347694 |
| 95 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.53504489 |
| 96 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.52355278 |
| 97 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.51940616 |
| 98 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.51344055 |
| 99 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.50596648 |
| 100 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.47508294 |
| 101 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.45993848 |
| 102 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.45980798 |
| 103 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.44821309 |
| 104 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.44091935 |
| 105 | RNA polymerase_Homo sapiens_hsa03020 | 0.43918531 |
| 106 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.43627370 |
| 107 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.43330074 |
| 108 | Lysosome_Homo sapiens_hsa04142 | 0.42990368 |
| 109 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.42462077 |
| 110 | Renin secretion_Homo sapiens_hsa04924 | 0.42018397 |
| 111 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41962649 |
| 112 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.41832155 |
| 113 | Tight junction_Homo sapiens_hsa04530 | 0.41553793 |
| 114 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.41213058 |
| 115 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40150485 |
| 116 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40009641 |
| 117 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39570599 |
| 118 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.39098801 |
| 119 | Purine metabolism_Homo sapiens_hsa00230 | 0.38508831 |
| 120 | Metabolic pathways_Homo sapiens_hsa01100 | 0.37522309 |
| 121 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.36902339 |
| 122 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.36853273 |
| 123 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.35453497 |
| 124 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.34360187 |
| 125 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.34279479 |
| 126 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.33999140 |
| 127 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.33964362 |
| 128 | Basal transcription factors_Homo sapiens_hsa03022 | 0.31885165 |
| 129 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.31420749 |
| 130 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.31121276 |
| 131 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.31033971 |
| 132 | Salmonella infection_Homo sapiens_hsa05132 | 0.29126411 |
| 133 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.28858797 |
| 134 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.25668326 |
| 135 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.24975413 |
| 136 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.24640787 |

