ANP32A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)5.38070243
2ribosomal small subunit biogenesis (GO:0042274)4.69118872
3DNA unwinding involved in DNA replication (GO:0006268)4.57847921
4DNA strand elongation involved in DNA replication (GO:0006271)4.49610316
5negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.47126172
6RNA stabilization (GO:0043489)4.39212877
7mRNA stabilization (GO:0048255)4.39212877
8DNA strand elongation (GO:0022616)4.32831240
9formation of translation preinitiation complex (GO:0001731)4.10515920
10RNA localization (GO:0006403)4.08771038
11negative regulation of RNA splicing (GO:0033119)3.99578383
12establishment of integrated proviral latency (GO:0075713)3.98021649
13glucocorticoid receptor signaling pathway (GO:0042921)3.97266474
14regulation of RNA export from nucleus (GO:0046831)3.94369124
15peptidyl-lysine dimethylation (GO:0018027)3.93933960
16viral transcription (GO:0019083)3.90248669
17mitotic sister chromatid cohesion (GO:0007064)3.88804049
18negative regulation of mRNA processing (GO:0050686)3.86015305
19regulation of translational fidelity (GO:0006450)3.80902350
20positive regulation of histone deacetylation (GO:0031065)3.80583643
21DNA replication initiation (GO:0006270)3.77763671
22megakaryocyte development (GO:0035855)3.77383821
23heterochromatin organization (GO:0070828)3.74681168
24telomere maintenance via semi-conservative replication (GO:0032201)3.73308469
25translational termination (GO:0006415)3.69741403
26protein localization to kinetochore (GO:0034501)3.68373768
27spliceosomal tri-snRNP complex assembly (GO:0000244)3.62537332
28nuclear pore complex assembly (GO:0051292)3.61420982
29positive regulation of RNA splicing (GO:0033120)3.61379622
30sister chromatid segregation (GO:0000819)3.60520199
31negative regulation of histone methylation (GO:0031061)3.57156482
32nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.56220287
33regulation of nucleobase-containing compound transport (GO:0032239)3.53237319
34nuclear pore organization (GO:0006999)3.51112970
35negative regulation of mRNA metabolic process (GO:1903312)3.48009417
36regulation of mRNA stability (GO:0043488)3.47150913
37regulation of sister chromatid cohesion (GO:0007063)3.43936293
38protein complex localization (GO:0031503)3.35033394
39alternative mRNA splicing, via spliceosome (GO:0000380)3.30945193
40ribosomal small subunit assembly (GO:0000028)3.30178371
41NLS-bearing protein import into nucleus (GO:0006607)3.27321484
42chromatin assembly (GO:0031497)3.26879836
43cellular protein complex localization (GO:0034629)3.24298041
443-UTR-mediated mRNA stabilization (GO:0070935)3.20584168
45maternal placenta development (GO:0001893)3.20010351
46DNA conformation change (GO:0071103)3.19776905
47regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.19606929
48maturation of SSU-rRNA (GO:0030490)3.17548909
49regulation of RNA stability (GO:0043487)3.17011272
50telomere maintenance via recombination (GO:0000722)3.16954498
51DNA duplex unwinding (GO:0032508)3.16026667
52pentose-phosphate shunt (GO:0006098)3.15834438
53cytoplasmic mRNA processing body assembly (GO:0033962)3.13392328
54chromosome condensation (GO:0030261)3.12191833
55DNA geometric change (GO:0032392)3.11973740
56translational elongation (GO:0006414)3.11337069
57mitotic sister chromatid segregation (GO:0000070)3.11335788
58dosage compensation (GO:0007549)3.11260617
59mitotic G1 DNA damage checkpoint (GO:0031571)3.08240298
60negative regulation of erythrocyte differentiation (GO:0045647)3.07052622
61DNA packaging (GO:0006323)3.06953220
62translational initiation (GO:0006413)3.06534531
63regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.06198796
64mitotic metaphase plate congression (GO:0007080)3.06018633
65V(D)J recombination (GO:0033151)3.05868156
66corticosteroid receptor signaling pathway (GO:0031958)3.05416554
67mitotic recombination (GO:0006312)3.05175271
68histone H2B ubiquitination (GO:0033523)3.02542461
69DNA topological change (GO:0006265)3.02181310
70positive regulation of gamma-delta T cell activation (GO:0046645)3.00968717
71protein complex disassembly (GO:0043241)2.98156049
72viral life cycle (GO:0019058)2.96783732
73intracellular estrogen receptor signaling pathway (GO:0030520)2.95322037
74protein export from nucleus (GO:0006611)2.94136565
75chromatin assembly or disassembly (GO:0006333)2.93504656
76establishment of apical/basal cell polarity (GO:0035089)2.93142873
77signal complex assembly (GO:0007172)2.93094043
78cellular protein complex disassembly (GO:0043624)2.92491801
79peptidyl-arginine omega-N-methylation (GO:0035247)2.92488945
80cellular hyperosmotic response (GO:0071474)2.92322902
81folic acid-containing compound biosynthetic process (GO:0009396)2.91726825
82establishment of viral latency (GO:0019043)2.90851070
83mitotic chromosome condensation (GO:0007076)2.88982431
84SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.85537518
85regulation of chromatin binding (GO:0035561)2.85514022
86ribonucleoprotein complex biogenesis (GO:0022613)2.84860814
87DNA synthesis involved in DNA repair (GO:0000731)2.84034873
88negative regulation of cell size (GO:0045792)2.83553169
89peptidyl-arginine methylation (GO:0018216)2.80838815
90peptidyl-arginine N-methylation (GO:0035246)2.80838815
91protein targeting to ER (GO:0045047)2.80284403
92regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.80192571
93protein-DNA complex disassembly (GO:0032986)2.78918160
94nucleosome disassembly (GO:0006337)2.78918160
95NADPH regeneration (GO:0006740)2.78324224
96cotranslational protein targeting to membrane (GO:0006613)2.77926957
97macromolecular complex disassembly (GO:0032984)2.77594826
98IMP biosynthetic process (GO:0006188)2.77514776
99embryonic foregut morphogenesis (GO:0048617)2.76204147
100positive regulation of SMAD protein import into nucleus (GO:0060391)2.76101469
101G1 DNA damage checkpoint (GO:0044783)2.75362313
102ATP-dependent chromatin remodeling (GO:0043044)2.75326946
103regulation of histone H3-K9 methylation (GO:0051570)2.73585723
104mRNA transport (GO:0051028)2.72218860
105establishment of protein localization to endoplasmic reticulum (GO:0072599)2.69878443
106trophectodermal cell differentiation (GO:0001829)2.69526439
107midgut development (GO:0007494)2.69354831
108IMP metabolic process (GO:0046040)2.69053631
109regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.68367342
110regulation of translational termination (GO:0006449)2.67232911
111regulation of NFAT protein import into nucleus (GO:0051532)2.67164563
112termination of RNA polymerase II transcription (GO:0006369)2.64766619
113insulin-like growth factor receptor signaling pathway (GO:0048009)2.62384905
114mRNA splice site selection (GO:0006376)2.61987262
115regulation of fatty acid beta-oxidation (GO:0031998)2.61621831
116positive regulation of gene expression, epigenetic (GO:0045815)2.61016827
117hippo signaling (GO:0035329)2.60452148
118polarized epithelial cell differentiation (GO:0030859)2.60436754
119protein localization to chromosome, centromeric region (GO:0071459)2.59988083
120mitotic G1/S transition checkpoint (GO:0044819)2.59762260
121planar cell polarity pathway involved in neural tube closure (GO:0090179)2.59329928
122paraxial mesoderm development (GO:0048339)2.58764525
123dicarboxylic acid biosynthetic process (GO:0043650)2.57277300
124establishment of nucleus localization (GO:0040023)2.57126152
125epithelial cell differentiation involved in prostate gland development (GO:0060742)2.56579759
126adherens junction assembly (GO:0034333)2.54837105
127negative regulation of DNA repair (GO:0045738)2.52976973
128positive regulation of chromosome segregation (GO:0051984)2.51476880
129layer formation in cerebral cortex (GO:0021819)2.50429096
130mitotic nuclear envelope disassembly (GO:0007077)2.49616167
131apoptotic process involved in morphogenesis (GO:0060561)2.49318398
132glial cell proliferation (GO:0014009)2.47836130
133regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.47823389
134negative regulation of heart growth (GO:0061117)2.46766759
135negative regulation of cardiac muscle tissue growth (GO:0055022)2.46766759
136RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.45748730
137mRNA splicing, via spliceosome (GO:0000398)2.45748730
138gastrulation with mouth forming second (GO:0001702)2.44863229
139DNA replication-dependent nucleosome organization (GO:0034723)2.42728679
140DNA replication-dependent nucleosome assembly (GO:0006335)2.42728679
141membrane disassembly (GO:0030397)2.41930487
142nuclear envelope disassembly (GO:0051081)2.41930487
143positive regulation of fatty acid beta-oxidation (GO:0032000)2.40889754
144histone H3-K9 demethylation (GO:0033169)2.40499827
145lysine catabolic process (GO:0006554)2.39618711
146lysine metabolic process (GO:0006553)2.39618711
147positive regulation of mitotic sister chromatid separation (GO:1901970)2.39146241
148positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.39146241
149positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.39146241
150ectodermal placode formation (GO:0060788)2.39022207
151pore complex assembly (GO:0046931)2.38472929
152RNA splicing, via transesterification reactions (GO:0000375)2.38067706
153positive regulation of protein deacetylation (GO:0090312)2.36983498
154chromatin silencing (GO:0006342)2.36155564

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.55072197
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.29815040
3* MYC_22102868_ChIP-Seq_BL_Human3.97747234
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.70103445
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.63292194
6HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.07997588
7* E2F4_17652178_ChIP-ChIP_JURKAT_Human2.45811631
8* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.43579086
9* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.42536464
10MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.42022226
11* KDM2B_26808549_Chip-Seq_DND41_Human2.41386844
12VDR_21846776_ChIP-Seq_THP-1_Human2.37168761
13* TCF7_22412390_ChIP-Seq_EML_Mouse2.27737517
14* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.23111763
15* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.22919901
16ZFP281_27345836_Chip-Seq_ESCs_Mouse2.19167747
17* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.12860451
18* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.10908361
19KDM2B_26808549_Chip-Seq_SUP-B15_Human2.08449585
20ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.06976770
21FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.96133284
22ZNF263_19887448_ChIP-Seq_K562_Human1.95277840
23ESR1_15608294_ChIP-ChIP_MCF-7_Human1.91519736
24* CLOCK_20551151_ChIP-Seq_293T_Human1.91047466
25MYC_19079543_ChIP-ChIP_MESCs_Mouse1.80975684
26EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.78938984
27* KDM2B_26808549_Chip-Seq_JURKAT_Human1.78440718
28POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.77004406
29NELFA_20434984_ChIP-Seq_ESCs_Mouse1.75483430
30ZFX_18555785_ChIP-Seq_MESCs_Mouse1.74442369
31* ELK3_25401928_ChIP-Seq_HUVEC_Human1.74139560
32KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.72536769
33DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.71951556
34ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.70829874
35* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.69800379
36* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.68598132
37* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68444781
38UTX_26944678_Chip-Seq_JUKART_Human1.65597547
39MYC_18555785_ChIP-Seq_MESCs_Mouse1.65588293
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.64276722
41LXR_22292898_ChIP-Seq_THP-1_Human1.63284363
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.62719784
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.61254265
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.57249608
45AR_21909140_ChIP-Seq_LNCAP_Human1.57237399
46* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.57110534
47NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.56387696
48* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.54838146
49ELF1_17652178_ChIP-ChIP_JURKAT_Human1.53807490
50PPARA_22158963_ChIP-Seq_LIVER_Mouse1.52944653
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.52350568
52* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.51763636
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50127485
54TTF2_22483619_ChIP-Seq_HELA_Human1.49550162
55* MAF_26560356_Chip-Seq_TH1_Human1.49193485
56PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.46674114
57TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.45587830
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.44660854
59SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.42277958
60KDM2B_26808549_Chip-Seq_K562_Human1.41013016
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.39654058
62THAP11_20581084_ChIP-Seq_MESCs_Mouse1.39248172
63NANOG_21062744_ChIP-ChIP_HESCs_Human1.37279908
64EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.36626380
65SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.36188670
66CREB1_26743006_Chip-Seq_LNCaP_Human1.36055455
67CIITA_25753668_ChIP-Seq_RAJI_Human1.35666732
68CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.35090847
69NCOR1_26117541_ChIP-Seq_K562_Human1.35059677
70* RXR_22158963_ChIP-Seq_LIVER_Mouse1.33723700
71RACK7_27058665_Chip-Seq_MCF-7_Human1.33043026
72* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.32476390
73SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.31445823
74* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.31015641
75CREB1_15753290_ChIP-ChIP_HEK293T_Human1.29517512
76CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.29433650
77* CHD1_26751641_Chip-Seq_LNCaP_Human1.29397400
78* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.29044926
79MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.27145833
80STAT6_21828071_ChIP-Seq_BEAS2B_Human1.25845955
81* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.25610800
82* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.23846735
83XRN2_22483619_ChIP-Seq_HELA_Human1.23512098
84POU5F1_16518401_ChIP-PET_MESCs_Mouse1.23208192
85HIF1A_21447827_ChIP-Seq_MCF-7_Human1.22059203
86CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.22029415
87SPI1_23547873_ChIP-Seq_NB4_Human1.21568991
88DCP1A_22483619_ChIP-Seq_HELA_Human1.17289254
89CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.16347267
90* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.15988541
91STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.15548033
92TP63_19390658_ChIP-ChIP_HaCaT_Human1.15486916
93PKCTHETA_26484144_Chip-Seq_BREAST_Human1.15066943
94CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.15009723
95* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14777877
96* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.14529362
97* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.14429104
98* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.14307901
99KDM5A_27292631_Chip-Seq_BREAST_Human1.13928126
100* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13783029
101* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.13731366
102ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13569381
103* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.13451986
104ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.13444779
105STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12963208
106* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.12906885
107* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.12510229
108E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11905408
109* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11402597
110* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11249601
111* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10670519
112ATF3_27146783_Chip-Seq_COLON_Human1.10614027
113MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.10356814
114HOXB4_20404135_ChIP-ChIP_EML_Mouse1.09561193
115RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09342593
116LXR_22158963_ChIP-Seq_LIVER_Mouse1.08227254
117* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.08213855
118KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.08209163
119KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.08209163
120KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.08209163
121* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.07497832
122DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07368162
123SALL1_21062744_ChIP-ChIP_HESCs_Human1.07033055
124MYB_26560356_Chip-Seq_TH1_Human1.05780794
125FOXP3_21729870_ChIP-Seq_TREG_Human1.04272997
126* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.03819966
127RUNX1_22412390_ChIP-Seq_EML_Mouse1.03675115
128GATA1_22383799_ChIP-Seq_G1ME_Mouse1.03370518
129* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.03243517
130KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01969610
131ETS1_20019798_ChIP-Seq_JURKAT_Human1.01747514
132SOX2_18555785_ChIP-Seq_MESCs_Mouse0.99417976
133NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.98790658
134* MAF_26560356_Chip-Seq_TH2_Human0.98149513
135* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97816752
136YY1_21170310_ChIP-Seq_MESCs_Mouse0.97143641
137BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96543374
138* MYB_26560356_Chip-Seq_TH2_Human0.95679688
139FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.95644999
140GABP_19822575_ChIP-Seq_HepG2_Human0.95535628
141* MYB_21317192_ChIP-Seq_ERMYB_Mouse0.95421224
142* VDR_24763502_ChIP-Seq_THP-1_Human0.94394704
143GATA6_25053715_ChIP-Seq_YYC3_Human0.93852612
144E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.92497534
145* NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.91794493
146JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.90998735
147P68_20966046_ChIP-Seq_HELA_Human0.90771293
148* MYC_19030024_ChIP-ChIP_MESCs_Mouse0.88859692
149DNAJC2_21179169_ChIP-ChIP_NT2_Human0.88805580
150TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88758422

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.22409248
2MP0010234_abnormal_vibrissa_follicle3.53257229
3MP0005076_abnormal_cell_differentiation3.17830342
4MP0002009_preneoplasia2.83307605
5MP0009053_abnormal_anal_canal2.78950615
6MP0002877_abnormal_melanocyte_morpholog2.70968124
7MP0010352_gastrointestinal_tract_polyps2.55977882
8MP0000537_abnormal_urethra_morphology2.40374159
9MP0003123_paternal_imprinting2.34914813
10MP0008932_abnormal_embryonic_tissue2.21665207
11MP0005451_abnormal_body_composition2.19529345
12MP0010030_abnormal_orbit_morphology2.16263977
13MP0001730_embryonic_growth_arrest2.14170598
14MP0004197_abnormal_fetal_growth/weight/2.08877829
15MP0003300_gastrointestinal_ulcer2.07762198
16MP0005187_abnormal_penis_morphology1.92922568
17MP0002084_abnormal_developmental_patter1.92252961
18MP0004185_abnormal_adipocyte_glucose1.91205750
19MP0003890_abnormal_embryonic-extraembry1.91106143
20MP0003303_peritoneal_inflammation1.90466484
21MP0005380_embryogenesis_phenotype1.89919464
22MP0001672_abnormal_embryogenesis/_devel1.89919464
23MP0009278_abnormal_bone_marrow1.88205969
24MP0003111_abnormal_nucleus_morphology1.86346350
25MP0002088_abnormal_embryonic_growth/wei1.86339870
26MP0004957_abnormal_blastocyst_morpholog1.85740055
27MP0003984_embryonic_growth_retardation1.85586122
28MP0002086_abnormal_extraembryonic_tissu1.83965477
29MP0005360_urolithiasis1.79625442
30MP0003567_abnormal_fetal_cardiomyocyte1.78037987
31MP0001849_ear_inflammation1.77489290
32MP0008961_abnormal_basal_metabolism1.75541322
33MP0008058_abnormal_DNA_repair1.71748615
34MP0002085_abnormal_embryonic_tissue1.68272009
35MP0009672_abnormal_birth_weight1.68177539
36MP0003077_abnormal_cell_cycle1.66263783
37MP0000490_abnormal_crypts_of1.65993764
38MP0000350_abnormal_cell_proliferation1.65450881
39MP0001697_abnormal_embryo_size1.63834617
40MP0008007_abnormal_cellular_replicative1.62506355
41MP0010307_abnormal_tumor_latency1.62104375
42MP0003119_abnormal_digestive_system1.58908526
43MP0000313_abnormal_cell_death1.57925201
44MP0002398_abnormal_bone_marrow1.55081411
45MP0003121_genomic_imprinting1.54422976
46MP0003763_abnormal_thymus_physiology1.53730414
47MP0008057_abnormal_DNA_replication1.52639204
48MP0010094_abnormal_chromosome_stability1.51262833
49MP0010368_abnormal_lymphatic_system1.47662329
50MP0009703_decreased_birth_body1.46666679
51MP0002080_prenatal_lethality1.42881207
52MP0005085_abnormal_gallbladder_physiolo1.40070938
53MP0002653_abnormal_ependyma_morphology1.39589120
54MP0000733_abnormal_muscle_development1.38318775
55MP0002139_abnormal_hepatobiliary_system1.36321033
56MP0004233_abnormal_muscle_weight1.35570516
57MP0002722_abnormal_immune_system1.34696606
58MP0003115_abnormal_respiratory_system1.34046915
59MP0005365_abnormal_bile_salt1.33362252
60MP0010630_abnormal_cardiac_muscle1.31283225
61MP0002166_altered_tumor_susceptibility1.29752596
62MP0002697_abnormal_eye_size1.28075775
63MP0005248_abnormal_Harderian_gland1.28011510
64MP0000428_abnormal_craniofacial_morphol1.25846962
65MP0009333_abnormal_splenocyte_physiolog1.23525715
66MP0002925_abnormal_cardiovascular_devel1.22107681
67MP0003122_maternal_imprinting1.21229190
68MP0003935_abnormal_craniofacial_develop1.21206010
69MP0003315_abnormal_perineum_morphology1.20733473
70MP0001293_anophthalmia1.18992115
71MP0000858_altered_metastatic_potential1.17600582
72MP0003436_decreased_susceptibility_to1.17413737
73MP0002092_abnormal_eye_morphology1.17198786
74MP0003252_abnormal_bile_duct1.15630690
75MP0004084_abnormal_cardiac_muscle1.13730335
76MP0003566_abnormal_cell_adhesion1.13151396
77MP0000689_abnormal_spleen_morphology1.12123889
78MP0005623_abnormal_meninges_morphology1.11124552
79MP0002429_abnormal_blood_cell1.10523953
80MP0008260_abnormal_autophagy1.10070552
81MP0005666_abnormal_adipose_tissue1.08425162
82MP0001915_intracranial_hemorrhage1.07801922
83MP0008770_decreased_survivor_rate1.06010169
84MP0000703_abnormal_thymus_morphology1.02286130
85MP0002396_abnormal_hematopoietic_system1.01220672
86MP0000266_abnormal_heart_morphology1.01141993
87MP0000716_abnormal_immune_system0.99594749
88MP0004808_abnormal_hematopoietic_stem0.98846994
89MP0002006_tumorigenesis0.98668410
90MP0003861_abnormal_nervous_system0.98044837
91MP0002932_abnormal_joint_morphology0.97264790
92MP0005621_abnormal_cell_physiology0.95112898
93MP0001835_abnormal_antigen_presentation0.94562905
94MP0010329_abnormal_lipoprotein_level0.93596273
95MP0000678_abnormal_parathyroid_gland0.93530236
96MP0006072_abnormal_retinal_apoptosis0.93069692
97MP0009379_abnormal_foot_pigmentation0.92983115
98MP0001346_abnormal_lacrimal_gland0.90663435
99MP0006035_abnormal_mitochondrial_morpho0.89192232
100MP0002420_abnormal_adaptive_immunity0.88537498
101MP0003283_abnormal_digestive_organ0.87818255
102MP0001819_abnormal_immune_cell0.87653084
103MP0003385_abnormal_body_wall0.87486923
104MP0001286_abnormal_eye_development0.87389154
105MP0005384_cellular_phenotype0.87057943
106MP0003787_abnormal_imprinting0.85752490
107MP0004264_abnormal_extraembryonic_tissu0.84568939
108MP0003221_abnormal_cardiomyocyte_apopto0.83925605
109MP0005501_abnormal_skin_physiology0.83920243
110MP0003693_abnormal_embryo_hatching0.82302271
111MP0004858_abnormal_nervous_system0.82262694
112MP0001800_abnormal_humoral_immune0.82174884
113MP0001545_abnormal_hematopoietic_system0.82104321
114MP0005397_hematopoietic_system_phenotyp0.82104321
115MP0003011_delayed_dark_adaptation0.80932003
116MP0005391_vision/eye_phenotype0.80842606
117MP0004130_abnormal_muscle_cell0.80632232
118MP0001784_abnormal_fluid_regulation0.80115581
119MP0004087_abnormal_muscle_fiber0.79905912
120MP0001661_extended_life_span0.79238434
121MP0002282_abnormal_trachea_morphology0.77182860
122MP0002111_abnormal_tail_morphology0.77100679
123MP0005375_adipose_tissue_phenotype0.77002015
124MP0002796_impaired_skin_barrier0.75683215
125MP0002089_abnormal_postnatal_growth/wei0.74948964
126MP0003453_abnormal_keratinocyte_physiol0.74847503
127MP0010678_abnormal_skin_adnexa0.74741697
128MP0005023_abnormal_wound_healing0.72967759
129MP0002128_abnormal_blood_circulation0.72153643
130MP0000609_abnormal_liver_physiology0.72104122
131MP0000358_abnormal_cell_content/0.69549819
132MP0000477_abnormal_intestine_morphology0.68824313
133MP0001727_abnormal_embryo_implantation0.68761208
134MP0002249_abnormal_larynx_morphology0.68713273
135MP0003656_abnormal_erythrocyte_physiolo0.68037069
136MP0002081_perinatal_lethality0.67803061
137MP0000534_abnormal_ureter_morphology0.67150156
138MP0002405_respiratory_system_inflammati0.66934078
139MP0000432_abnormal_head_morphology0.66915405
140MP0003942_abnormal_urinary_system0.65880898
141MP0001348_abnormal_lacrimal_gland0.65615178
142MP0002452_abnormal_antigen_presenting0.65412610
143MP0002723_abnormal_immune_serum0.65403472
144MP0002019_abnormal_tumor_incidence0.65101564
145MP0000685_abnormal_immune_system0.65062070
146MP0001614_abnormal_blood_vessel0.64766146

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)3.62101242
2Pseudobulbar signs (HP:0002200)3.55752234
3Renal duplication (HP:0000075)3.36470535
4Ependymoma (HP:0002888)3.27181922
5Increased nuchal translucency (HP:0010880)3.18309844
6Volvulus (HP:0002580)3.08882115
7Abnormality of the lower motor neuron (HP:0002366)3.05997280
8Progressive muscle weakness (HP:0003323)2.88621870
9Reticulocytopenia (HP:0001896)2.88055947
10Abnormality of the 4th metacarpal (HP:0010012)2.86839598
11Macroorchidism (HP:0000053)2.85795607
12Astrocytoma (HP:0009592)2.83583730
13Abnormality of the astrocytes (HP:0100707)2.83583730
14Chromosomal breakage induced by crosslinking agents (HP:0003221)2.77735075
15Progressive external ophthalmoplegia (HP:0000590)2.77476272
16Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.74552279
17Short 4th metacarpal (HP:0010044)2.74552279
18Elfin facies (HP:0004428)2.70905197
19Renovascular hypertension (HP:0100817)2.68222186
20Chromsome breakage (HP:0040012)2.63758873
21Deep venous thrombosis (HP:0002625)2.57720520
22Rectal prolapse (HP:0002035)2.57333732
23Insomnia (HP:0100785)2.55862166
24Spastic diplegia (HP:0001264)2.55143357
25Abnormality of cells of the erythroid lineage (HP:0012130)2.51470304
26Missing ribs (HP:0000921)2.49784322
27Metaphyseal cupping (HP:0003021)2.48186420
28Shallow orbits (HP:0000586)2.46135308
29Deep palmar crease (HP:0006191)2.45252386
30Cellulitis (HP:0100658)2.42317620
31Dysmetric saccades (HP:0000641)2.41844415
32Annular pancreas (HP:0001734)2.41816086
33Hypochromic microcytic anemia (HP:0004840)2.40696437
34Ankyloglossia (HP:0010296)2.39031506
35Pointed chin (HP:0000307)2.38621676
36Acute lymphatic leukemia (HP:0006721)2.36625447
3711 pairs of ribs (HP:0000878)2.36433363
38Overriding aorta (HP:0002623)2.35950477
39Lymphangioma (HP:0100764)2.34543621
40Back pain (HP:0003418)2.31524272
41High anterior hairline (HP:0009890)2.31018437
42Pallor (HP:0000980)2.30065603
43Obsessive-compulsive behavior (HP:0000722)2.29634986
44Cerebral aneurysm (HP:0004944)2.29510592
45Ulnar bowing (HP:0003031)2.25641989
46Deep philtrum (HP:0002002)2.24225162
47Abnormality of reticulocytes (HP:0004312)2.22896393
48Fibrous tissue neoplasm (HP:0012316)2.22563439
49Malignant gastrointestinal tract tumors (HP:0006749)2.21527350
50Gastrointestinal carcinoma (HP:0002672)2.21527350
51Abnormality of the calcaneus (HP:0008364)2.20832651
52Abnormality of the diencephalon (HP:0010662)2.20356407
53Selective tooth agenesis (HP:0001592)2.20302301
54Proximal placement of thumb (HP:0009623)2.20088217
55Neoplasm of striated muscle (HP:0009728)2.18073558
56Enlarged penis (HP:0000040)2.17867581
57Posterior subcapsular cataract (HP:0007787)2.17582919
58Fibroma (HP:0010614)2.17549902
59Recurrent viral infections (HP:0004429)2.16832437
60Cutis marmorata (HP:0000965)2.16537376
61Nephroblastoma (Wilms tumor) (HP:0002667)2.15834514
62Acute myeloid leukemia (HP:0004808)2.15782162
63Adenoma sebaceum (HP:0009720)2.15281152
64Angiofibromas (HP:0010615)2.15281152
65Colon cancer (HP:0003003)2.13619951
66Supernumerary ribs (HP:0005815)2.08444148
67Deviation of the thumb (HP:0009603)2.08102818
68Subacute progressive viral hepatitis (HP:0006572)2.07134442
69Macrocytic anemia (HP:0001972)2.07132103
70Viral hepatitis (HP:0006562)2.06063164
71Heterotopia (HP:0002282)2.04102470
72Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.03941279
73Rhabdomyosarcoma (HP:0002859)2.03322068
74Syringomyelia (HP:0003396)2.02339894
75Spinal cord lesions (HP:0100561)2.02339894
76Sacral dimple (HP:0000960)2.01298550
77Abnormality of cochlea (HP:0000375)2.00948214
78Aplasia/Hypoplasia of the thymus (HP:0010515)2.00805208
79Basal cell carcinoma (HP:0002671)1.98884278
80Abnormality of the fingertips (HP:0001211)1.98737973
81Eczematoid dermatitis (HP:0000976)1.98663256
82Glioma (HP:0009733)1.97215319
83Increased density of long bones (HP:0006392)1.97137972
84Rib fusion (HP:0000902)1.97045913
85Biliary tract neoplasm (HP:0100574)1.96690822
86Overlapping toe (HP:0001845)1.95261887
87IgM deficiency (HP:0002850)1.95084413
88High pitched voice (HP:0001620)1.94555462
89Abnormality of oral frenula (HP:0000190)1.93837440
90Skin tags (HP:0010609)1.93774509
91Deviation of the hallux (HP:0010051)1.92256250
92Reticulocytosis (HP:0001923)1.92031341
93Embryonal renal neoplasm (HP:0011794)1.91134720
94Mitral valve prolapse (HP:0001634)1.91025492
95Abnormal number of incisors (HP:0011064)1.90130031
96Chronic obstructive pulmonary disease (HP:0006510)1.90072282
97Obstructive lung disease (HP:0006536)1.90072282
98Myelodysplasia (HP:0002863)1.89856441
99Hallux valgus (HP:0001822)1.89777178
100Intestinal polyp (HP:0005266)1.89522346
101Recurrent abscess formation (HP:0002722)1.89479230
102Insidious onset (HP:0003587)1.89138021
103Termporal pattern (HP:0011008)1.89138021
104Abnormality of chromosome segregation (HP:0002916)1.88516680
105Broad thumb (HP:0011304)1.88433679
106Abnormality of the Achilles tendon (HP:0005109)1.88154401
107Medulloblastoma (HP:0002885)1.87657798
108Abnormality of the distal phalanx of the thumb (HP:0009617)1.87636109
109Large earlobe (HP:0009748)1.87397368
110Centrally nucleated skeletal muscle fibers (HP:0003687)1.86309305
111Premature ovarian failure (HP:0008209)1.85905333
112Intestinal polyposis (HP:0200008)1.85635162
113Long palpebral fissure (HP:0000637)1.84692462
114Long eyelashes (HP:0000527)1.84629598
115Skull defect (HP:0001362)1.83455566
116Vertebral arch anomaly (HP:0008438)1.83059207
117Atresia of the external auditory canal (HP:0000413)1.82791373
118Birth length less than 3rd percentile (HP:0003561)1.82382739
119Cafe-au-lait spot (HP:0000957)1.81105302
120Abnormal number of erythroid precursors (HP:0012131)1.80518296
121Multiple enchondromatosis (HP:0005701)1.79770153
122Meningitis (HP:0001287)1.79534169
123Trigonocephaly (HP:0000243)1.78874760
124Agammaglobulinemia (HP:0004432)1.77651558
125Disproportionate tall stature (HP:0001519)1.77551590
126Achilles tendon contracture (HP:0001771)1.77191826
127Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.77083987
128Resting tremor (HP:0002322)1.76933428
129Microvesicular hepatic steatosis (HP:0001414)1.75703815
130Orthostatic hypotension (HP:0001278)1.75594071
131Aneurysm (HP:0002617)1.75171892
132Broad palm (HP:0001169)1.74125293
133Abnormality of the thoracic spine (HP:0100711)1.74067319
134Thoracic kyphosis (HP:0002942)1.74050242
135Colitis (HP:0002583)1.73110779
136Arnold-Chiari malformation (HP:0002308)1.72908466
137Ragged-red muscle fibers (HP:0003200)1.72520987
138Papilloma (HP:0012740)1.71893725
139Verrucae (HP:0200043)1.71893725
140Bowel diverticulosis (HP:0005222)1.71701403
141Hepatoblastoma (HP:0002884)1.71676854
142Recurrent bacterial skin infections (HP:0005406)1.71274348
143Slow saccadic eye movements (HP:0000514)1.70742522
144Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.70124159
145Short 1st metacarpal (HP:0010034)1.70124159
146Short phalanx of the thumb (HP:0009660)1.69350917
147Uterine neoplasm (HP:0010784)1.69339970
148Supernumerary bones of the axial skeleton (HP:0009144)1.69329760
149Flared metaphyses (HP:0003015)1.68918367
150Attention deficit hyperactivity disorder (HP:0007018)1.68878748
151Cortical dysplasia (HP:0002539)1.67117041
152Hamartoma of the eye (HP:0010568)1.67074330
153Personality changes (HP:0000751)1.66489862
154Esophageal atresia (HP:0002032)1.65588634
155Gastrointestinal inflammation (HP:0004386)1.65323711
156Abnormality of the parietal bone (HP:0002696)1.64829504
157Pendular nystagmus (HP:0012043)1.64812119
158Leiomyosarcoma (HP:0100243)1.64703508
159Uterine leiomyosarcoma (HP:0002891)1.64703508
160Lymphoma (HP:0002665)1.64609468
161Thrombocytosis (HP:0001894)1.64509423
162Asymmetry of the thorax (HP:0001555)1.64252908
163Trismus (HP:0000211)1.64053126
164Neoplasm of the oral cavity (HP:0100649)1.63957817
165Abnormality of the left ventricular outflow tract (HP:0011103)1.63951470
166Subaortic stenosis (HP:0001682)1.63951470
167Aplasia/Hypoplasia of the sacrum (HP:0008517)1.62250976
168Abnormality of the thymus (HP:0000777)1.62200375
169Panhypogammaglobulinemia (HP:0003139)1.62119736
170Short 5th finger (HP:0009237)1.61771504
171Transitional cell carcinoma of the bladder (HP:0006740)1.60757548

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PKN24.11327766
2TRIB33.98435031
3MAP3K103.71869141
4EEF2K3.67306733
5SMG13.39031691
6CDK123.38115927
7PRPF4B2.57812914
8CDC72.48578046
9NEK12.33480087
10ALK2.26438216
11RIPK12.16759820
12SRPK11.98662324
13ICK1.87288321
14PTK61.78541719
15NEK21.72403420
16SIK21.71952446
17CDK61.71848350
18PDGFRA1.69201645
19VRK21.67681914
20TYRO31.62797553
21RIPK41.61990099
22GRK61.59653336
23BUB11.57232024
24STK101.46384104
25LRRK21.45786901
26SIK11.43690107
27CDK41.43327929
28RPS6KB21.40148685
29YES11.39930007
30TAF11.35834264
31BMX1.30305216
32MAP3K131.27032307
33PAK41.26552406
34CAMK1G1.22708950
35FGFR21.17787018
36MTOR1.12532953
37CAMK1D1.10494906
38FGFR11.08754108
39TTN1.08477559
40EIF2AK11.05225167
41KSR21.04239321
42CHEK21.03085146
43NME20.99489199
44MAP4K10.98279591
45IRAK40.98086693
46MAP3K80.95789930
47MAP2K30.94712371
48TTK0.93232609
49MAP3K70.90529867
50DMPK0.89957244
51CLK10.89667611
52BRD40.89147973
53ERN10.86831942
54FGFR30.85143086
55TSSK60.83996646
56LATS10.82727074
57KSR10.82377646
58SCYL20.82158288
59FGFR40.82012370
60ILK0.81710437
61PASK0.81370737
62WEE10.81180682
63MAP3K140.79893174
64BLK0.78982947
65CHEK10.78947601
66PAK20.78582312
67PAK60.76817671
68DYRK1B0.75987784
69PLK40.75012842
70PDGFRB0.74435814
71EPHB20.73686728
72UHMK10.72501516
73CDK20.72245320
74CDK70.70863707
75PDPK10.69617240
76TGFBR10.68562518
77RET0.68490169
78MKNK10.68216349
79ERBB20.67445528
80TAOK10.67433174
81CSNK1E0.67136812
82BTK0.65344842
83PRKCH0.64466652
84ITK0.64080785
85DDR20.62894178
86CSNK1D0.62643646
87TESK20.62465853
88FES0.62209215
89DYRK30.61938591
90LATS20.60810063
91ATR0.60675280
92CAMKK10.57856654
93LMTK20.57080407
94MAPK110.56537183
95BRAF0.56104081
96HIPK20.55537953
97AURKA0.55391975
98CAMK40.53875876
99CSK0.53642709
100ATM0.51973079
101CDK90.50954156
102FGR0.50857648
103CDK10.49937361
104MAP3K10.49155136
105EIF2AK20.49021249
106CDK11A0.48956660
107AKT20.48437814
108RPS6KA10.48077589
109STK240.47867538
110RPS6KA40.47600320
111SGK30.47472794
112MAP2K20.47011474
113RPS6KC10.46981249
114RPS6KL10.46981249
115PRKDC0.46487493
116IRAK30.45411965
117KDR0.45332205
118CDK150.45242240
119JAK20.44707719
120STK40.44291785
121PNCK0.44130761
122PRKD10.44049407
123MARK20.44016920
124RAF10.43816288
125MAPK140.43411171
126STK110.43236141
127PRKCI0.43010718
128STK30.42046324
129AURKB0.41755884
130PBK0.41180598
131IRAK20.41176675
132PLK10.41089495
133ARAF0.41088172
134PRKD30.40451826
135MAPK100.40094728
136MELK0.39959854
137PTK20.39815986
138CDK180.39090361
139MAP3K90.38626090
140EGFR0.36499923
141PIM10.35596792
142TGFBR20.34971468
143FLT30.33781706
144MKNK20.33709939
145PLK30.33677140

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.70994250
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.86341550
3Ribosome_Homo sapiens_hsa030102.43339131
4Base excision repair_Homo sapiens_hsa034102.34405589
5Lysine degradation_Homo sapiens_hsa003102.15352722
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.08844626
7Arginine biosynthesis_Homo sapiens_hsa002202.05467435
82-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.84439665
9mTOR signaling pathway_Homo sapiens_hsa041501.83712193
10Chronic myeloid leukemia_Homo sapiens_hsa052201.80427474
11mRNA surveillance pathway_Homo sapiens_hsa030151.76800056
12Spliceosome_Homo sapiens_hsa030401.73716026
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.73145895
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.72601148
15Non-homologous end-joining_Homo sapiens_hsa034501.68391371
16Biosynthesis of amino acids_Homo sapiens_hsa012301.56037529
17Non-small cell lung cancer_Homo sapiens_hsa052231.51733976
18Pentose phosphate pathway_Homo sapiens_hsa000301.50200396
19Nucleotide excision repair_Homo sapiens_hsa034201.49591050
20One carbon pool by folate_Homo sapiens_hsa006701.44513126
21Central carbon metabolism in cancer_Homo sapiens_hsa052301.40963846
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.38451502
23Notch signaling pathway_Homo sapiens_hsa043301.36263212
24Colorectal cancer_Homo sapiens_hsa052101.32773038
25Glioma_Homo sapiens_hsa052141.32076268
26Primary bile acid biosynthesis_Homo sapiens_hsa001201.26867546
27Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.26645190
28Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.24767372
29MicroRNAs in cancer_Homo sapiens_hsa052061.23924398
30RNA transport_Homo sapiens_hsa030131.21105827
31Endometrial cancer_Homo sapiens_hsa052131.20282208
32Basal cell carcinoma_Homo sapiens_hsa052171.18718946
33Proteoglycans in cancer_Homo sapiens_hsa052051.17051113
34Adherens junction_Homo sapiens_hsa045201.15266515
35Hippo signaling pathway_Homo sapiens_hsa043901.14137245
36Epstein-Barr virus infection_Homo sapiens_hsa051691.10549415
37Carbon metabolism_Homo sapiens_hsa012001.10163356
38Bile secretion_Homo sapiens_hsa049761.09019984
39VEGF signaling pathway_Homo sapiens_hsa043701.08290999
40Thyroid hormone signaling pathway_Homo sapiens_hsa049191.08023880
41Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.07447651
42Herpes simplex infection_Homo sapiens_hsa051681.06880629
43Homologous recombination_Homo sapiens_hsa034401.04095886
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.03682407
45Hepatitis B_Homo sapiens_hsa051611.02131554
46Renal cell carcinoma_Homo sapiens_hsa052111.01499356
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.01389812
48Phototransduction_Homo sapiens_hsa047440.98419748
49Bladder cancer_Homo sapiens_hsa052190.97688765
50Estrogen signaling pathway_Homo sapiens_hsa049150.96925338
51Measles_Homo sapiens_hsa051620.96094415
52Pyrimidine metabolism_Homo sapiens_hsa002400.95968359
53Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95669415
54Cell cycle_Homo sapiens_hsa041100.94423224
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.91467812
56Small cell lung cancer_Homo sapiens_hsa052220.90106616
57Cyanoamino acid metabolism_Homo sapiens_hsa004600.89755299
58Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.89498779
59Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.88945323
60Pancreatic cancer_Homo sapiens_hsa052120.87767822
61AMPK signaling pathway_Homo sapiens_hsa041520.85997697
62HTLV-I infection_Homo sapiens_hsa051660.85933356
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.85930742
64Insulin resistance_Homo sapiens_hsa049310.85780076
65Apoptosis_Homo sapiens_hsa042100.84364334
66Choline metabolism in cancer_Homo sapiens_hsa052310.84352155
67Leishmaniasis_Homo sapiens_hsa051400.84319096
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.84238451
69Fatty acid degradation_Homo sapiens_hsa000710.83871264
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.82514938
71B cell receptor signaling pathway_Homo sapiens_hsa046620.82406061
72Oocyte meiosis_Homo sapiens_hsa041140.82364135
73Thyroid cancer_Homo sapiens_hsa052160.81928744
74Viral myocarditis_Homo sapiens_hsa054160.81835699
75T cell receptor signaling pathway_Homo sapiens_hsa046600.79248540
76Insulin signaling pathway_Homo sapiens_hsa049100.79166906
77DNA replication_Homo sapiens_hsa030300.78685798
78Glucagon signaling pathway_Homo sapiens_hsa049220.78677425
79Mismatch repair_Homo sapiens_hsa034300.78394706
80Acute myeloid leukemia_Homo sapiens_hsa052210.77784364
81RNA degradation_Homo sapiens_hsa030180.77718046
82HIF-1 signaling pathway_Homo sapiens_hsa040660.76752651
83Hedgehog signaling pathway_Homo sapiens_hsa043400.76646589
84Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.75537087
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75336318
86Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.74683690
87Primary immunodeficiency_Homo sapiens_hsa053400.73615147
88Tryptophan metabolism_Homo sapiens_hsa003800.73596676
89Dorso-ventral axis formation_Homo sapiens_hsa043200.71656902
90NF-kappa B signaling pathway_Homo sapiens_hsa040640.71254522
91Fatty acid metabolism_Homo sapiens_hsa012120.70869749
92Toll-like receptor signaling pathway_Homo sapiens_hsa046200.68815390
93Viral carcinogenesis_Homo sapiens_hsa052030.68713779
94Wnt signaling pathway_Homo sapiens_hsa043100.68608078
95Osteoclast differentiation_Homo sapiens_hsa043800.68598379
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67724252
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67359584
98Fatty acid biosynthesis_Homo sapiens_hsa000610.67205599
99Type II diabetes mellitus_Homo sapiens_hsa049300.66683533
100Long-term potentiation_Homo sapiens_hsa047200.66489626
101Focal adhesion_Homo sapiens_hsa045100.66189633
102Fanconi anemia pathway_Homo sapiens_hsa034600.65507122
103Leukocyte transendothelial migration_Homo sapiens_hsa046700.65378364
104Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.65356513
105Tight junction_Homo sapiens_hsa045300.65180120
106Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64491877
107Shigellosis_Homo sapiens_hsa051310.63489472
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.62761942
109Influenza A_Homo sapiens_hsa051640.62362661
110Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62286135
111Prostate cancer_Homo sapiens_hsa052150.61473838
112Selenocompound metabolism_Homo sapiens_hsa004500.60179269
113Rap1 signaling pathway_Homo sapiens_hsa040150.58302077
114Prion diseases_Homo sapiens_hsa050200.57200958
115AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.56487220
116Pathways in cancer_Homo sapiens_hsa052000.56384578
117Butanoate metabolism_Homo sapiens_hsa006500.56303538
118Prolactin signaling pathway_Homo sapiens_hsa049170.56251603
119ErbB signaling pathway_Homo sapiens_hsa040120.56019562
120PPAR signaling pathway_Homo sapiens_hsa033200.55188460
121Hepatitis C_Homo sapiens_hsa051600.54722145
122Melanogenesis_Homo sapiens_hsa049160.54420088
123Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.54318260
124Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51629120
125Cysteine and methionine metabolism_Homo sapiens_hsa002700.50776453
126Complement and coagulation cascades_Homo sapiens_hsa046100.47979334
127Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47816869
128Platelet activation_Homo sapiens_hsa046110.47645504
129Antigen processing and presentation_Homo sapiens_hsa046120.47461073
130FoxO signaling pathway_Homo sapiens_hsa040680.47107752
131cGMP-PKG signaling pathway_Homo sapiens_hsa040220.46514675
132Sulfur relay system_Homo sapiens_hsa041220.45287146
133Phospholipase D signaling pathway_Homo sapiens_hsa040720.44514570
134Chemokine signaling pathway_Homo sapiens_hsa040620.44189670
135p53 signaling pathway_Homo sapiens_hsa041150.42939933
136Tuberculosis_Homo sapiens_hsa051520.40662829
137Systemic lupus erythematosus_Homo sapiens_hsa053220.40496966
138Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38368374
139Inositol phosphate metabolism_Homo sapiens_hsa005620.36469589
140Phosphatidylinositol signaling system_Homo sapiens_hsa040700.35210128
141Alcoholism_Homo sapiens_hsa050340.34547325

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