

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 9.70335363 |
| 2 | tolerance induction (GO:0002507) | 9.44964025 |
| 3 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 9.14095104 |
| 4 | negative regulation of glycogen biosynthetic process (GO:0045719) | 8.98464915 |
| 5 | regulation of oxidative stress-induced neuron death (GO:1903203) | 8.97561256 |
| 6 | galactose catabolic process (GO:0019388) | 8.88680796 |
| 7 | N-terminal protein amino acid acetylation (GO:0006474) | 8.77871525 |
| 8 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 8.51090310 |
| 9 | regulation of energy homeostasis (GO:2000505) | 8.27983912 |
| 10 | negative regulation of muscle hypertrophy (GO:0014741) | 8.27092179 |
| 11 | interleukin-6-mediated signaling pathway (GO:0070102) | 8.21309363 |
| 12 | membrane tubulation (GO:0097320) | 8.14535624 |
| 13 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 7.87322032 |
| 14 | regulation of cellular respiration (GO:0043457) | 7.38778923 |
| 15 | negative regulation of glycogen metabolic process (GO:0070874) | 7.23637773 |
| 16 | protein localization to endosome (GO:0036010) | 7.13486766 |
| 17 | cellular response to interleukin-6 (GO:0071354) | 6.54656864 |
| 18 | ribosomal small subunit biogenesis (GO:0042274) | 6.45825238 |
| 19 | cysteine metabolic process (GO:0006534) | 6.04560966 |
| 20 | forebrain morphogenesis (GO:0048853) | 6.02919922 |
| 21 | sequestering of actin monomers (GO:0042989) | 5.90264176 |
| 22 | protein heterotetramerization (GO:0051290) | 5.62087605 |
| 23 | response to interleukin-6 (GO:0070741) | 5.31921752 |
| 24 | ubiquinone biosynthetic process (GO:0006744) | 5.22392137 |
| 25 | ribonucleoprotein complex biogenesis (GO:0022613) | 5.11962129 |
| 26 | response to nitrosative stress (GO:0051409) | 5.06354742 |
| 27 | viral transcription (GO:0019083) | 5.02915136 |
| 28 | galactose metabolic process (GO:0006012) | 5.01585534 |
| 29 | ribosome biogenesis (GO:0042254) | 4.99917925 |
| 30 | ubiquinone metabolic process (GO:0006743) | 4.89286453 |
| 31 | translational termination (GO:0006415) | 4.77664409 |
| 32 | spermatid nucleus differentiation (GO:0007289) | 4.67474427 |
| 33 | ribosomal large subunit biogenesis (GO:0042273) | 4.50420037 |
| 34 | quinone biosynthetic process (GO:1901663) | 4.37608770 |
| 35 | valine metabolic process (GO:0006573) | 4.17115269 |
| 36 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 4.15668736 |
| 37 | viral life cycle (GO:0019058) | 4.10248945 |
| 38 | otic vesicle formation (GO:0030916) | 4.06585124 |
| 39 | L-phenylalanine catabolic process (GO:0006559) | 4.03409815 |
| 40 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 4.03409815 |
| 41 | regulation of the force of heart contraction (GO:0002026) | 3.97598517 |
| 42 | N-terminal protein amino acid modification (GO:0031365) | 3.96289699 |
| 43 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.91513809 |
| 44 | cotranslational protein targeting to membrane (GO:0006613) | 3.90112410 |
| 45 | negative regulation of potassium ion transport (GO:0043267) | 3.89666071 |
| 46 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.88708259 |
| 47 | cellular response to nicotine (GO:0071316) | 3.84961421 |
| 48 | tyrosine metabolic process (GO:0006570) | 3.79833373 |
| 49 | protein targeting to ER (GO:0045047) | 3.78116352 |
| 50 | cellular protein complex disassembly (GO:0043624) | 3.76088648 |
| 51 | regulation of respiratory gaseous exchange (GO:0043576) | 3.73212330 |
| 52 | cell proliferation in forebrain (GO:0021846) | 3.66405220 |
| 53 | translational elongation (GO:0006414) | 3.65328301 |
| 54 | dendrite development (GO:0016358) | 3.63531429 |
| 55 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.59372155 |
| 56 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.57885177 |
| 57 | megakaryocyte development (GO:0035855) | 3.56647731 |
| 58 | regulation of hypersensitivity (GO:0002883) | 3.53474858 |
| 59 | protein localization to endoplasmic reticulum (GO:0070972) | 3.51282798 |
| 60 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.50678884 |
| 61 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.45941467 |
| 62 | cellular component biogenesis (GO:0044085) | 3.41758201 |
| 63 | vesicle fusion (GO:0006906) | 3.40622241 |
| 64 | regulation of proton transport (GO:0010155) | 3.40614970 |
| 65 | lymph node development (GO:0048535) | 3.35767645 |
| 66 | regulation of mitochondrial depolarization (GO:0051900) | 3.34416303 |
| 67 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.33052160 |
| 68 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.33052160 |
| 69 | L-phenylalanine metabolic process (GO:0006558) | 3.30953036 |
| 70 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.30953036 |
| 71 | positive regulation of T cell apoptotic process (GO:0070234) | 3.25506329 |
| 72 | protein complex disassembly (GO:0043241) | 3.25392234 |
| 73 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.22814423 |
| 74 | Peyers patch development (GO:0048541) | 3.22814423 |
| 75 | regulation of cardiac muscle hypertrophy (GO:0010611) | 3.17762678 |
| 76 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.17443003 |
| 77 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.17443003 |
| 78 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.17443003 |
| 79 | isoprenoid biosynthetic process (GO:0008299) | 3.09298215 |
| 80 | regulation of muscle hypertrophy (GO:0014743) | 3.07625758 |
| 81 | superoxide anion generation (GO:0042554) | 3.05391261 |
| 82 | response to insecticide (GO:0017085) | 3.05113585 |
| 83 | innate immune response in mucosa (GO:0002227) | 3.04839713 |
| 84 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.04786471 |
| 85 | maturation of 5.8S rRNA (GO:0000460) | 3.04588127 |
| 86 | endosome to pigment granule transport (GO:0043485) | 3.04240399 |
| 87 | endosome to melanosome transport (GO:0035646) | 3.04240399 |
| 88 | oligosaccharide biosynthetic process (GO:0009312) | 3.04050677 |
| 89 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 3.03414561 |
| 90 | positive regulation of positive chemotaxis (GO:0050927) | 3.03388832 |
| 91 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.02112301 |
| 92 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 3.00337403 |
| 93 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.00018569 |
| 94 | mucosal immune response (GO:0002385) | 2.98971920 |
| 95 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.95813546 |
| 96 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.95813546 |
| 97 | regulation of positive chemotaxis (GO:0050926) | 2.94675506 |
| 98 | macromolecular complex disassembly (GO:0032984) | 2.93744806 |
| 99 | regulation of mesoderm development (GO:2000380) | 2.91714692 |
| 100 | ribosomal small subunit assembly (GO:0000028) | 2.90572532 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 6.37862897 |
| 2 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 3.96291743 |
| 3 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.40796195 |
| 4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.75867219 |
| 5 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.70289065 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.56516349 |
| 7 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.52128237 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.51681506 |
| 9 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 2.42431615 |
| 10 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.36263057 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.32548782 |
| 12 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.31615289 |
| 13 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.31615289 |
| 14 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.31615289 |
| 15 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.28968566 |
| 16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.23224034 |
| 17 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.12921047 |
| 18 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.99774710 |
| 19 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.91093243 |
| 20 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.87791852 |
| 21 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.85606555 |
| 22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.85544077 |
| 23 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.74446317 |
| 24 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.71230242 |
| 25 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.70290973 |
| 26 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.70182624 |
| 27 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.65897082 |
| 28 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.65796532 |
| 29 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.65178810 |
| 30 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.60292069 |
| 31 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.56157348 |
| 32 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.55717174 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.52338648 |
| 34 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.51939115 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.50738879 |
| 36 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.50395376 |
| 37 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.50325403 |
| 38 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.48782659 |
| 39 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.46606431 |
| 40 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.46606431 |
| 41 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.45903705 |
| 42 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.45871996 |
| 43 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.44890375 |
| 44 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.44787042 |
| 45 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.43435110 |
| 46 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.40197782 |
| 47 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.37776201 |
| 48 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.32316687 |
| 49 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.30263697 |
| 50 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.29912256 |
| 51 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.28335000 |
| 52 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.26880771 |
| 53 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.26245641 |
| 54 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.23679304 |
| 55 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.18368209 |
| 56 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.16143842 |
| 57 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14827904 |
| 58 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14827904 |
| 59 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.12234340 |
| 60 | FUS_26573619_Chip-Seq_HEK293_Human | 1.11900095 |
| 61 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.10802295 |
| 62 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.08503746 |
| 63 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.06138371 |
| 64 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.05228583 |
| 65 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.05136834 |
| 66 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.04848965 |
| 67 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.04412151 |
| 68 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02624944 |
| 69 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.02475537 |
| 70 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.01941806 |
| 71 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.01808222 |
| 72 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.01009820 |
| 73 | SA1_27219007_Chip-Seq_Bcells_Human | 1.00557589 |
| 74 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.99280588 |
| 75 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.99056698 |
| 76 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.97930744 |
| 77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96226757 |
| 78 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.96092332 |
| 79 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94097167 |
| 80 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.93088956 |
| 81 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.92685002 |
| 82 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91907048 |
| 83 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.91281982 |
| 84 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.90552773 |
| 85 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.89506611 |
| 86 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.88902682 |
| 87 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88060939 |
| 88 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.87957848 |
| 89 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.86807618 |
| 90 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.85934093 |
| 91 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.85850518 |
| 92 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.85694197 |
| 93 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.85653517 |
| 94 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.84198994 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.82121106 |
| 96 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.82106129 |
| 97 | P300_27268052_Chip-Seq_Bcells_Human | 0.82040975 |
| 98 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.81819694 |
| 99 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.81709683 |
| 100 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.81037599 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006054_spinal_hemorrhage | 9.57833343 |
| 2 | MP0002653_abnormal_ependyma_morphology | 6.19950294 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 5.78924798 |
| 4 | MP0005623_abnormal_meninges_morphology | 5.32299848 |
| 5 | MP0004084_abnormal_cardiac_muscle | 4.75957415 |
| 6 | MP0001348_abnormal_lacrimal_gland | 3.67155131 |
| 7 | MP0003279_aneurysm | 3.61101396 |
| 8 | MP0001915_intracranial_hemorrhage | 3.29722957 |
| 9 | MP0004145_abnormal_muscle_electrophysio | 2.76253664 |
| 10 | MP0004036_abnormal_muscle_relaxation | 2.60116613 |
| 11 | MP0009379_abnormal_foot_pigmentation | 2.45252215 |
| 12 | MP0006292_abnormal_olfactory_placode | 2.33438302 |
| 13 | MP0004215_abnormal_myocardial_fiber | 2.17692296 |
| 14 | MP0001986_abnormal_taste_sensitivity | 2.04387650 |
| 15 | MP0004484_altered_response_of | 1.97650060 |
| 16 | MP0004130_abnormal_muscle_cell | 1.97406897 |
| 17 | MP0001346_abnormal_lacrimal_gland | 1.55869035 |
| 18 | MP0002822_catalepsy | 1.39792166 |
| 19 | MP0003186_abnormal_redox_activity | 1.38968131 |
| 20 | MP0002163_abnormal_gland_morphology | 1.34665568 |
| 21 | MP0001764_abnormal_homeostasis | 1.33490478 |
| 22 | MP0005379_endocrine/exocrine_gland_phen | 1.25803428 |
| 23 | MP0003195_calcinosis | 1.21331401 |
| 24 | MP0009765_abnormal_xenobiotic_induced | 1.19550789 |
| 25 | MP0008872_abnormal_physiological_respon | 1.19048071 |
| 26 | MP0001661_extended_life_span | 1.18065613 |
| 27 | MP0009333_abnormal_splenocyte_physiolog | 1.15765017 |
| 28 | MP0010155_abnormal_intestine_physiology | 1.14190606 |
| 29 | MP0003303_peritoneal_inflammation | 1.12955506 |
| 30 | MP0005220_abnormal_exocrine_pancreas | 1.10819212 |
| 31 | MP0000767_abnormal_smooth_muscle | 1.06719831 |
| 32 | MP0003011_delayed_dark_adaptation | 1.06109054 |
| 33 | MP0002733_abnormal_thermal_nociception | 1.05696795 |
| 34 | MP0002693_abnormal_pancreas_physiology | 1.05685872 |
| 35 | MP0003633_abnormal_nervous_system | 1.03245097 |
| 36 | MP0005448_abnormal_energy_balance | 1.00988257 |
| 37 | MP0009785_altered_susceptibility_to | 1.00565126 |
| 38 | MP0001286_abnormal_eye_development | 0.99407288 |
| 39 | MP0003300_gastrointestinal_ulcer | 0.95154020 |
| 40 | MP0003878_abnormal_ear_physiology | 0.93820744 |
| 41 | MP0005377_hearing/vestibular/ear_phenot | 0.93820744 |
| 42 | MP0002697_abnormal_eye_size | 0.93465113 |
| 43 | MP0005197_abnormal_uvea_morphology | 0.92537450 |
| 44 | MP0009250_abnormal_appendicular_skeleto | 0.92292335 |
| 45 | MP0002972_abnormal_cardiac_muscle | 0.91016020 |
| 46 | MP0005165_increased_susceptibility_to | 0.89990400 |
| 47 | MP0003631_nervous_system_phenotype | 0.89533950 |
| 48 | MP0000678_abnormal_parathyroid_gland | 0.88568216 |
| 49 | MP0008775_abnormal_heart_ventricle | 0.83698342 |
| 50 | MP0001340_abnormal_eyelid_morphology | 0.83051326 |
| 51 | MP0001501_abnormal_sleep_pattern | 0.82315847 |
| 52 | MP0002272_abnormal_nervous_system | 0.80942408 |
| 53 | MP0002736_abnormal_nociception_after | 0.80059265 |
| 54 | MP0001800_abnormal_humoral_immune | 0.79886354 |
| 55 | MP0002160_abnormal_reproductive_system | 0.77968213 |
| 56 | MP0001968_abnormal_touch/_nociception | 0.73570464 |
| 57 | MP0001970_abnormal_pain_threshold | 0.70198035 |
| 58 | MP0005410_abnormal_fertilization | 0.70189755 |
| 59 | MP0009046_muscle_twitch | 0.68210963 |
| 60 | MP0005334_abnormal_fat_pad | 0.64894770 |
| 61 | MP0010030_abnormal_orbit_morphology | 0.63726200 |
| 62 | MP0003693_abnormal_embryo_hatching | 0.62776385 |
| 63 | MP0005423_abnormal_somatic_nervous | 0.61093537 |
| 64 | MP0002734_abnormal_mechanical_nocicepti | 0.60335879 |
| 65 | MP0000465_gastrointestinal_hemorrhage | 0.59180440 |
| 66 | MP0009745_abnormal_behavioral_response | 0.57992403 |
| 67 | MP0002735_abnormal_chemical_nociception | 0.56928473 |
| 68 | MP0005266_abnormal_metabolism | 0.55836882 |
| 69 | MP0005376_homeostasis/metabolism_phenot | 0.55670993 |
| 70 | MP0005193_abnormal_anterior_eye | 0.55431126 |
| 71 | MP0002723_abnormal_immune_serum | 0.54764898 |
| 72 | MP0001905_abnormal_dopamine_level | 0.54267247 |
| 73 | MP0001544_abnormal_cardiovascular_syste | 0.53213402 |
| 74 | MP0005385_cardiovascular_system_phenoty | 0.53213402 |
| 75 | MP0004185_abnormal_adipocyte_glucose | 0.53008340 |
| 76 | MP0004742_abnormal_vestibular_system | 0.51341374 |
| 77 | MP0005671_abnormal_response_to | 0.51269981 |
| 78 | MP0000049_abnormal_middle_ear | 0.50776282 |
| 79 | MP0002896_abnormal_bone_mineralization | 0.50731648 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.48948072 |
| 81 | MP0005645_abnormal_hypothalamus_physiol | 0.47411608 |
| 82 | MP0003632_abnormal_nervous_system | 0.46840942 |
| 83 | MP0002751_abnormal_autonomic_nervous | 0.46647517 |
| 84 | MP0003880_abnormal_central_pattern | 0.46633816 |
| 85 | MP0002106_abnormal_muscle_physiology | 0.45121093 |
| 86 | MP0003724_increased_susceptibility_to | 0.44643904 |
| 87 | MP0005620_abnormal_muscle_contractility | 0.44157240 |
| 88 | MP0003959_abnormal_lean_body | 0.43583149 |
| 89 | MP0003119_abnormal_digestive_system | 0.43023015 |
| 90 | MP0006276_abnormal_autonomic_nervous | 0.42456580 |
| 91 | MP0003252_abnormal_bile_duct | 0.42034289 |
| 92 | MP0000477_abnormal_intestine_morphology | 0.41634893 |
| 93 | MP0005253_abnormal_eye_physiology | 0.41337837 |
| 94 | MP0005551_abnormal_eye_electrophysiolog | 0.39489384 |
| 95 | MP0003646_muscle_fatigue | 0.38883607 |
| 96 | MP0003936_abnormal_reproductive_system | 0.38431316 |
| 97 | MP0002116_abnormal_craniofacial_bone | 0.38194600 |
| 98 | MP0005389_reproductive_system_phenotype | 0.37793199 |
| 99 | MP0005310_abnormal_salivary_gland | 0.37736900 |
| 100 | MP0009763_increased_sensitivity_to | 0.37422774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Progressive inability to walk (HP:0002505) | 7.78614626 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 6.09993654 |
| 3 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.09993654 |
| 4 | Mutism (HP:0002300) | 6.03529994 |
| 5 | Hypergonadotropic hypogonadism (HP:0000815) | 5.74375744 |
| 6 | Premature ovarian failure (HP:0008209) | 5.42821153 |
| 7 | Abnormal ciliary motility (HP:0012262) | 5.22555554 |
| 8 | Abnormal number of erythroid precursors (HP:0012131) | 4.76670309 |
| 9 | Chronic otitis media (HP:0000389) | 4.75654341 |
| 10 | Loss of speech (HP:0002371) | 4.35585397 |
| 11 | Disinhibition (HP:0000734) | 4.32635769 |
| 12 | Inability to walk (HP:0002540) | 4.28833676 |
| 13 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.27243328 |
| 14 | Dyskinesia (HP:0100660) | 4.00714340 |
| 15 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.95691723 |
| 16 | Renal duplication (HP:0000075) | 3.84796783 |
| 17 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.74199992 |
| 18 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.74199992 |
| 19 | Aortic regurgitation (HP:0001659) | 3.65357562 |
| 20 | Anophthalmia (HP:0000528) | 3.50043250 |
| 21 | Submucous cleft hard palate (HP:0000176) | 3.47860585 |
| 22 | Progressive muscle weakness (HP:0003323) | 3.44256260 |
| 23 | Overriding aorta (HP:0002623) | 3.39075040 |
| 24 | Chronic sinusitis (HP:0011109) | 3.38681284 |
| 25 | Hepatocellular necrosis (HP:0001404) | 3.02488701 |
| 26 | Elfin facies (HP:0004428) | 2.99659011 |
| 27 | Rhinitis (HP:0012384) | 2.93421372 |
| 28 | Acute necrotizing encephalopathy (HP:0006965) | 2.75154041 |
| 29 | Renovascular hypertension (HP:0100817) | 2.72816236 |
| 30 | True hermaphroditism (HP:0010459) | 2.58724239 |
| 31 | Agammaglobulinemia (HP:0004432) | 2.56417178 |
| 32 | Stomatitis (HP:0010280) | 2.50959423 |
| 33 | Apathy (HP:0000741) | 2.47958908 |
| 34 | Flat cornea (HP:0007720) | 2.40296228 |
| 35 | Diminished motivation (HP:0000745) | 2.38640585 |
| 36 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.36978832 |
| 37 | Cystic liver disease (HP:0006706) | 2.34779438 |
| 38 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.34611199 |
| 39 | Enlarged epiphyses (HP:0010580) | 2.34513316 |
| 40 | Restlessness (HP:0000711) | 2.33877189 |
| 41 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.32976487 |
| 42 | Inappropriate behavior (HP:0000719) | 2.32495114 |
| 43 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.31857410 |
| 44 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.31398844 |
| 45 | Hepatic necrosis (HP:0002605) | 2.27193135 |
| 46 | Pancreatic fibrosis (HP:0100732) | 2.23946130 |
| 47 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.21479757 |
| 48 | Optic disc pallor (HP:0000543) | 2.21319303 |
| 49 | Sclerocornea (HP:0000647) | 2.21006554 |
| 50 | Progressive macrocephaly (HP:0004481) | 2.20240554 |
| 51 | Rib fusion (HP:0000902) | 2.14735257 |
| 52 | Hypoplasia of the uterus (HP:0000013) | 2.14236822 |
| 53 | Progressive cerebellar ataxia (HP:0002073) | 2.14037244 |
| 54 | Acute encephalopathy (HP:0006846) | 2.12374932 |
| 55 | Insomnia (HP:0100785) | 2.12285082 |
| 56 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.11537260 |
| 57 | Bulbous nose (HP:0000414) | 2.11110588 |
| 58 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.10397463 |
| 59 | Short middle phalanx of the 5th finger (HP:0004220) | 2.08713063 |
| 60 | Drooling (HP:0002307) | 2.08165864 |
| 61 | Genetic anticipation (HP:0003743) | 2.06791763 |
| 62 | Pseudobulbar signs (HP:0002200) | 2.05442650 |
| 63 | Mitochondrial inheritance (HP:0001427) | 2.05366244 |
| 64 | Excessive salivation (HP:0003781) | 2.04402870 |
| 65 | Abnormality of alanine metabolism (HP:0010916) | 2.03627556 |
| 66 | Hyperalaninemia (HP:0003348) | 2.03627556 |
| 67 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.03627556 |
| 68 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.02775902 |
| 69 | Chronic hepatic failure (HP:0100626) | 11.3733199 |
| 70 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.98491793 |
| 71 | Delayed epiphyseal ossification (HP:0002663) | 1.96789866 |
| 72 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.94816930 |
| 73 | Adrenal hypoplasia (HP:0000835) | 1.94721701 |
| 74 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.94614564 |
| 75 | Personality changes (HP:0000751) | 1.93134906 |
| 76 | Synostosis of carpal bones (HP:0005048) | 1.93082868 |
| 77 | Sepsis (HP:0100806) | 1.91659296 |
| 78 | Hyperacusis (HP:0010780) | 1.90826945 |
| 79 | Specific learning disability (HP:0001328) | 1.89195188 |
| 80 | Widely patent fontanelles and sutures (HP:0004492) | 1.88830777 |
| 81 | Ankle clonus (HP:0011448) | 1.88769469 |
| 82 | Abnormality of the diencephalon (HP:0010662) | 1.87723741 |
| 83 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.84653961 |
| 84 | Increased serum lactate (HP:0002151) | 1.83085796 |
| 85 | Pancreatic cysts (HP:0001737) | 1.81677445 |
| 86 | Sensory axonal neuropathy (HP:0003390) | 1.81336642 |
| 87 | Adducted thumb (HP:0001181) | 1.79665632 |
| 88 | Mitral regurgitation (HP:0001653) | 1.79426599 |
| 89 | Long nose (HP:0003189) | 1.77037266 |
| 90 | Babinski sign (HP:0003487) | 1.69489054 |
| 91 | Chronic diarrhea (HP:0002028) | 1.66674912 |
| 92 | Leukodystrophy (HP:0002415) | 1.66403992 |
| 93 | Abnormality of macular pigmentation (HP:0008002) | 1.66340681 |
| 94 | Pallor (HP:0000980) | 1.65189744 |
| 95 | Abnormality of the costochondral junction (HP:0000919) | 1.64960456 |
| 96 | Focal motor seizures (HP:0011153) | 1.61069310 |
| 97 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.60756764 |
| 98 | Macrocytic anemia (HP:0001972) | 1.60297203 |
| 99 | Action tremor (HP:0002345) | 1.58744830 |
| 100 | Mesomelia (HP:0003027) | 1.58263431 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K13 | 5.79244217 |
| 2 | CAMKK1 | 5.50079656 |
| 3 | TXK | 3.50755235 |
| 4 | RIPK4 | 2.87900215 |
| 5 | BRSK2 | 2.32948247 |
| 6 | MAP3K14 | 2.20311494 |
| 7 | CAMKK2 | 2.05355627 |
| 8 | SIK2 | 2.05059952 |
| 9 | PASK | 11.3179965 |
| 10 | MAP4K1 | 1.97789391 |
| 11 | LRRK2 | 1.72334245 |
| 12 | WNK4 | 1.24723833 |
| 13 | DYRK3 | 1.17735840 |
| 14 | MAP2K7 | 1.16777722 |
| 15 | GRK7 | 1.16015743 |
| 16 | JAK3 | 1.12366044 |
| 17 | BTK | 1.03216601 |
| 18 | ZAK | 1.02623049 |
| 19 | MAP3K4 | 0.98965805 |
| 20 | BRSK1 | 0.95437461 |
| 21 | NEK1 | 0.90105069 |
| 22 | MAP3K7 | 0.87642606 |
| 23 | TEC | 0.87360752 |
| 24 | CSNK1G2 | 0.83333717 |
| 25 | CSNK1G3 | 0.82521345 |
| 26 | INSRR | 0.80189990 |
| 27 | CSNK1A1L | 0.78802012 |
| 28 | ADRBK2 | 0.78780541 |
| 29 | SYK | 0.78415036 |
| 30 | NEK2 | 0.75675599 |
| 31 | PAK6 | 0.69666640 |
| 32 | PRKCQ | 0.67007693 |
| 33 | CSNK1G1 | 0.64360544 |
| 34 | TYRO3 | 0.63424533 |
| 35 | PTK6 | 0.60822216 |
| 36 | MAPK13 | 0.58905353 |
| 37 | CLK1 | 0.57126202 |
| 38 | DYRK2 | 0.56540509 |
| 39 | MARK1 | 0.56366098 |
| 40 | TSSK6 | 0.56146874 |
| 41 | LCK | 0.56054955 |
| 42 | MST4 | 0.55996399 |
| 43 | MAPKAPK3 | 0.55101200 |
| 44 | CHUK | 0.52799431 |
| 45 | IKBKB | 0.50456473 |
| 46 | ITK | 0.47158851 |
| 47 | TLK1 | 0.46836079 |
| 48 | WNK3 | 0.46707492 |
| 49 | PLK4 | 0.44869198 |
| 50 | SGK494 | 0.44432991 |
| 51 | SGK223 | 0.44432991 |
| 52 | BMPR1B | 0.43807819 |
| 53 | CASK | 0.43305786 |
| 54 | STK39 | 0.42380000 |
| 55 | STK38 | 0.41956804 |
| 56 | FGR | 0.41408441 |
| 57 | PRKAA2 | 0.36019815 |
| 58 | TIE1 | 0.35580558 |
| 59 | ADRBK1 | 0.34661701 |
| 60 | MAP3K6 | 0.34647910 |
| 61 | PRKCZ | 0.33546709 |
| 62 | SGK1 | 0.31303520 |
| 63 | EPHB2 | 0.30861351 |
| 64 | GRK5 | 0.30657494 |
| 65 | PRKCD | 0.30158753 |
| 66 | STK16 | 0.29800754 |
| 67 | MARK3 | 0.29508189 |
| 68 | STK11 | 0.28846243 |
| 69 | GRK1 | 0.28134329 |
| 70 | EPHA4 | 0.27810064 |
| 71 | STK4 | 0.25459271 |
| 72 | YES1 | 0.24612902 |
| 73 | OXSR1 | 0.24557959 |
| 74 | RPS6KA5 | 0.24450969 |
| 75 | CAMK2B | 0.23750684 |
| 76 | CDC7 | 0.23634497 |
| 77 | BCR | 0.23499374 |
| 78 | FRK | 0.23499332 |
| 79 | MAP2K4 | 0.23304492 |
| 80 | OBSCN | 0.23070714 |
| 81 | MUSK | 0.22479503 |
| 82 | ACVR1B | 0.21417358 |
| 83 | MAP4K2 | 0.20863622 |
| 84 | JAK2 | 0.20082137 |
| 85 | VRK1 | 0.19956563 |
| 86 | PLK1 | 0.19677506 |
| 87 | TGFBR1 | 0.19240530 |
| 88 | LYN | 0.19235872 |
| 89 | ERBB2 | 0.19106798 |
| 90 | PAK1 | 0.19020805 |
| 91 | ZAP70 | 0.18593805 |
| 92 | MAPK14 | 0.16522301 |
| 93 | MAPK15 | 0.15411159 |
| 94 | MATK | 0.15295671 |
| 95 | UHMK1 | 0.14433037 |
| 96 | WEE1 | 0.13585755 |
| 97 | CDK14 | 0.13328455 |
| 98 | AURKA | 0.13284123 |
| 99 | PRKCA | 0.11380152 |
| 100 | MAPKAPK2 | 0.10824463 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 6.38453842 |
| 2 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 4.36152327 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 4.29285711 |
| 4 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 3.01670888 |
| 5 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.82703791 |
| 6 | Cocaine addiction_Homo sapiens_hsa05030 | 2.74305302 |
| 7 | Galactose metabolism_Homo sapiens_hsa00052 | 2.46232227 |
| 8 | Olfactory transduction_Homo sapiens_hsa04740 | 1.83261314 |
| 9 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.81245750 |
| 10 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.73984115 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.68206807 |
| 12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.65127820 |
| 13 | Insulin secretion_Homo sapiens_hsa04911 | 1.55510627 |
| 14 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.51339840 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.50182522 |
| 16 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.41708612 |
| 17 | Nicotine addiction_Homo sapiens_hsa05033 | 1.34488743 |
| 18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.31834519 |
| 19 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.30989075 |
| 20 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.30336342 |
| 21 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.29031624 |
| 22 | Alcoholism_Homo sapiens_hsa05034 | 1.26435838 |
| 23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.24925535 |
| 24 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.23723016 |
| 25 | Morphine addiction_Homo sapiens_hsa05032 | 1.23422783 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.20871587 |
| 27 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.19878973 |
| 28 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.13986760 |
| 29 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.12193547 |
| 30 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.11699468 |
| 31 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.11432127 |
| 32 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.08248788 |
| 33 | Long-term potentiation_Homo sapiens_hsa04720 | 1.06844493 |
| 34 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.04266920 |
| 35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.02913821 |
| 36 | Shigellosis_Homo sapiens_hsa05131 | 1.02634629 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.98380476 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.97441349 |
| 39 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.94641494 |
| 40 | Asthma_Homo sapiens_hsa05310 | 0.92855599 |
| 41 | Allograft rejection_Homo sapiens_hsa05330 | 0.89004572 |
| 42 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.88812789 |
| 43 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.88456680 |
| 44 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.83212624 |
| 45 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80208568 |
| 46 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.79210262 |
| 47 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.78203520 |
| 48 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.77208885 |
| 49 | Taste transduction_Homo sapiens_hsa04742 | 0.75142065 |
| 50 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.74209242 |
| 51 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.73092024 |
| 52 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.72471536 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.71150801 |
| 54 | GABAergic synapse_Homo sapiens_hsa04727 | 0.71100109 |
| 55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.71086182 |
| 56 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.70671112 |
| 57 | Apoptosis_Homo sapiens_hsa04210 | 0.65397798 |
| 58 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.64072201 |
| 59 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.63081299 |
| 60 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60922643 |
| 61 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.59711331 |
| 62 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.59337679 |
| 63 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.58416824 |
| 64 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.54681531 |
| 65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.54532291 |
| 66 | RNA degradation_Homo sapiens_hsa03018 | 0.53493136 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52547134 |
| 68 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.52282679 |
| 69 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.51509967 |
| 70 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.50746726 |
| 71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.50617046 |
| 72 | Pertussis_Homo sapiens_hsa05133 | 0.50406837 |
| 73 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.47853467 |
| 74 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47318863 |
| 75 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.47254608 |
| 76 | Hepatitis B_Homo sapiens_hsa05161 | 0.45180627 |
| 77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.45034580 |
| 78 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.43729254 |
| 79 | Prostate cancer_Homo sapiens_hsa05215 | 0.42990358 |
| 80 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.42448373 |
| 81 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.41736143 |
| 82 | Measles_Homo sapiens_hsa05162 | 0.39261217 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.36434411 |
| 84 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.36090942 |
| 85 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.35221235 |
| 86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.34621167 |
| 87 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.34412546 |
| 88 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.33882660 |
| 89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.32528421 |
| 90 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.32193954 |
| 91 | Viral myocarditis_Homo sapiens_hsa05416 | 0.32060664 |
| 92 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.29741786 |
| 93 | Proteasome_Homo sapiens_hsa03050 | 0.28715545 |
| 94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.28710230 |
| 95 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.28495169 |
| 96 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.28363536 |
| 97 | HTLV-I infection_Homo sapiens_hsa05166 | 0.27710511 |
| 98 | Circadian entrainment_Homo sapiens_hsa04713 | 0.25893958 |
| 99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25437023 |
| 100 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.24193891 |

