ANXA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.51858190
2wound healing, spreading of epidermal cells (GO:0035313)4.44272871
3response to peptidoglycan (GO:0032494)4.10989929
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.99300319
5wound healing, spreading of cells (GO:0044319)3.87832685
6endodermal cell differentiation (GO:0035987)3.82495929
7production of molecular mediator involved in inflammatory response (GO:0002532)3.78455093
8neutrophil activation (GO:0042119)3.75166511
9cell adhesion mediated by integrin (GO:0033627)3.73947568
10detection of other organism (GO:0098543)3.70598880
11leukocyte aggregation (GO:0070486)3.69616801
12positive regulation of monocyte chemotaxis (GO:0090026)3.63613548
13granulocyte activation (GO:0036230)3.62607225
14hemidesmosome assembly (GO:0031581)3.60249559
15positive regulation of osteoblast proliferation (GO:0033690)3.58281934
16positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.54497553
17negative regulation of nitric oxide biosynthetic process (GO:0045019)3.53702489
18cellular response to interferon-alpha (GO:0035457)3.53253904
19desmosome organization (GO:0002934)3.52600648
20leukocyte migration involved in inflammatory response (GO:0002523)3.50171162
21modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.43341611
22modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.43341611
23positive regulation by organism of defense response of other organism involved in symbiotic interact3.43341611
24modulation by symbiont of host immune response (GO:0052553)3.43341611
25positive regulation by symbiont of host defense response (GO:0052509)3.43341611
26modulation by symbiont of host defense response (GO:0052031)3.43341611
27response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.38915905
28response to host immune response (GO:0052572)3.38915905
29mature B cell differentiation involved in immune response (GO:0002313)3.36053769
30regulation of monocyte chemotaxis (GO:0090025)3.35581301
31detection of bacterium (GO:0016045)3.34928522
32membrane raft organization (GO:0031579)3.28540272
33skin morphogenesis (GO:0043589)3.28387989
34respiratory burst (GO:0045730)3.27972869
35response to fungus (GO:0009620)3.26522721
36negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.25723929
37hypotonic response (GO:0006971)3.24738680
38regulation of tolerance induction (GO:0002643)3.24532067
39positive regulation of tolerance induction (GO:0002645)3.16800849
40regulation of natural killer cell differentiation (GO:0032823)3.15219888
41response to host defenses (GO:0052200)3.14902572
42response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.14902572
43response to host (GO:0075136)3.14902572
44regulation of metalloenzyme activity (GO:0048552)3.03795644
45positive regulation of interferon-alpha production (GO:0032727)2.99157270
46natural killer cell mediated immunity (GO:0002228)2.99065972
47natural killer cell mediated cytotoxicity (GO:0042267)2.99065972
48positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.96793903
49Arp2/3 complex-mediated actin nucleation (GO:0034314)2.96236886
50regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.95245429
51collagen fibril organization (GO:0030199)2.94778923
52pinocytosis (GO:0006907)2.94722139
53regulation of integrin-mediated signaling pathway (GO:2001044)2.90034967
54negative regulation of mast cell activation (GO:0033004)2.87008113
55defense response to fungus (GO:0050832)2.86828355
56positive regulation of endothelial cell apoptotic process (GO:2000353)2.86782192
57regulation of mononuclear cell migration (GO:0071675)2.86148556
58positive regulation of mast cell degranulation (GO:0043306)2.83935070
59positive regulation of mast cell activation involved in immune response (GO:0033008)2.83935070
60negative regulation of interleukin-12 production (GO:0032695)2.83803273
61positive regulation of leukocyte degranulation (GO:0043302)2.83483395
62superoxide anion generation (GO:0042554)2.83291797
63detection of external biotic stimulus (GO:0098581)2.80578241
64hydrogen peroxide biosynthetic process (GO:0050665)2.80046425
65macrophage activation involved in immune response (GO:0002281)2.79876341
66sequestering of metal ion (GO:0051238)2.79455350
67regulation of interferon-alpha production (GO:0032647)2.78565394
68positive regulation of gamma-delta T cell activation (GO:0046645)2.78536541
69immunoglobulin mediated immune response (GO:0016064)2.77848119
70regulation of T cell tolerance induction (GO:0002664)2.75900478
71chondrocyte proliferation (GO:0035988)2.74744902
72chronic inflammatory response (GO:0002544)2.71777677
73regulation of interferon-beta biosynthetic process (GO:0045357)2.68972623
74response to interferon-alpha (GO:0035455)2.68915622
75response to progesterone (GO:0032570)2.67274879
76positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.67156755
77positive regulation of natural killer cell differentiation (GO:0032825)2.67045214
78cellular extravasation (GO:0045123)2.65414915
79fibril organization (GO:0097435)2.65005984
80positive regulation of mast cell activation (GO:0033005)2.64263317
81antigen processing and presentation of endogenous antigen (GO:0019883)2.64176813
82collagen metabolic process (GO:0032963)2.64174596
83regulation of hypersensitivity (GO:0002883)2.63721024
84response to muramyl dipeptide (GO:0032495)2.62175409
85metanephric mesenchyme development (GO:0072075)2.60341729
86reactive oxygen species biosynthetic process (GO:1903409)2.59318861
87B cell mediated immunity (GO:0019724)2.59001590
88collagen catabolic process (GO:0030574)2.58992961
89mature B cell differentiation (GO:0002335)2.57491551
90protein localization to endosome (GO:0036010)2.57421135
91regulation of podosome assembly (GO:0071801)2.54779808
92regulation of mast cell activation (GO:0033003)2.54691982
93interferon-gamma-mediated signaling pathway (GO:0060333)2.54481241
94negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.54349183
95apoptotic cell clearance (GO:0043277)2.53953757
96positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.53903429
97positive regulation of actin filament depolymerization (GO:0030836)2.52444153
98regulation of leukocyte degranulation (GO:0043300)2.52207852
99positive regulation of chemokine biosynthetic process (GO:0045080)2.50922107
100myeloid cell activation involved in immune response (GO:0002275)2.50339898
101regulation of chemokine biosynthetic process (GO:0045073)2.50336964
102regulation of dendritic cell antigen processing and presentation (GO:0002604)2.50084964
103regulation of macrophage cytokine production (GO:0010935)2.48933333
104regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.48827916
105kidney mesenchyme development (GO:0072074)2.48672219
106barbed-end actin filament capping (GO:0051016)2.48192201
107lipoxygenase pathway (GO:0019372)2.47042112
108detection of molecule of bacterial origin (GO:0032490)2.47042102
109antigen processing and presentation via MHC class Ib (GO:0002475)2.46704078
110positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.45572519
111neutrophil mediated immunity (GO:0002446)2.45329455
112extracellular matrix disassembly (GO:0022617)2.43652745
113positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.43118902
114lipopolysaccharide-mediated signaling pathway (GO:0031663)2.41229084
115multicellular organismal macromolecule metabolic process (GO:0044259)2.41058140
116positive regulation of interleukin-6 production (GO:0032755)2.40962163
117detection of biotic stimulus (GO:0009595)2.40674649
118positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.40175686
119mesodermal cell differentiation (GO:0048333)2.39418168
120regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.39178391
121actin nucleation (GO:0045010)2.39114643
122keratinocyte proliferation (GO:0043616)2.39016778
123regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.37556248
124regulation of mast cell degranulation (GO:0043304)2.36881547
125regulation of mast cell activation involved in immune response (GO:0033006)2.36574530
126positive regulation of toll-like receptor signaling pathway (GO:0034123)2.36571538
127regulation of B cell receptor signaling pathway (GO:0050855)2.36562328
128leukocyte mediated cytotoxicity (GO:0001909)2.35455415
129positive regulation of interleukin-8 secretion (GO:2000484)2.35250557
130regulation of myeloid leukocyte mediated immunity (GO:0002886)2.34010632
131muscle cell migration (GO:0014812)2.33381065
132multicellular organismal catabolic process (GO:0044243)2.33314220
133regulation of interleukin-6 production (GO:0032675)2.32410028
134keratan sulfate catabolic process (GO:0042340)2.31960250
135positive regulation of extracellular matrix organization (GO:1903055)2.31547743
136* peptide cross-linking (GO:0018149)2.31375576
137positive regulation of interleukin-1 production (GO:0032732)2.30894955
138negative regulation of nitric-oxide synthase activity (GO:0051001)2.30862467
139myoblast migration (GO:0051451)2.30796640
140antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.30224960
141cellular response to thyroid hormone stimulus (GO:0097067)2.30080516
142phagocytosis, engulfment (GO:0006911)2.29606627
143substrate-dependent cell migration (GO:0006929)2.28468982
144extracellular fibril organization (GO:0043206)2.28424757
145establishment of endothelial barrier (GO:0061028)2.27815420
146regulation of vitamin D biosynthetic process (GO:0060556)2.23878965
147positive regulation of lamellipodium assembly (GO:0010592)2.22320453
148negative regulation of cell killing (GO:0031342)2.21664359
149negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.21664359
150regulation of antigen processing and presentation (GO:0002577)2.21212788
151regulation of interleukin-17 production (GO:0032660)2.20943718
152positive regulation of interleukin-1 beta production (GO:0032731)2.19593060
153positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.19309987
154cellular response to exogenous dsRNA (GO:0071360)2.18113904
155regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)2.17646553
156regulation of T cell receptor signaling pathway (GO:0050856)2.17375445
157positive regulation of interleukin-1 secretion (GO:0050716)2.16723475
158negative regulation of T cell mediated immunity (GO:0002710)2.15605469

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.18883267
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse5.18654092
3* TRIM28_21343339_ChIP-Seq_HEK293_Human4.10002379
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.90065082
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.67155540
6* RARG_19884340_ChIP-ChIP_MEFs_Mouse3.50207464
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.27182846
8Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.93997290
9* FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.92994597
10* SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.80011871
11RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.79687831
12MYB_21317192_ChIP-Seq_ERMYB_Mouse2.79064075
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.63743419
14IRF8_27001747_Chip-Seq_BMDM_Mouse2.58173990
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.57945836
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.52604101
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.46501688
18* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.31819678
19* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.31819678
20* CJUN_26792858_Chip-Seq_BT549_Human2.14807156
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.11297833
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.10136158
23MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.03333791
24* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.03185404
25SOX2_20726797_ChIP-Seq_SW620_Human1.99221703
26TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.98248105
27STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.98101603
28STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.95619221
29ESR1_21235772_ChIP-Seq_MCF-7_Human1.92841763
30IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.85242198
31PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.84609842
32BRD4_27068464_Chip-Seq_AML-cells_Mouse1.84097896
33* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.81723420
34* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.79561730
35NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.79306012
36* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.75639386
37* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.74275310
38* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.74275310
39GATA2_21666600_ChIP-Seq_HMVEC_Human1.72145765
40IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.63342275
41* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.62248464
42HIF1A_21447827_ChIP-Seq_MCF-7_Human1.61116030
43* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.59903364
44CLOCK_20551151_ChIP-Seq_293T_Human1.59506420
45CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.52678095
46SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.51700927
47* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.51700619
48TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.48265049
49FOXO3_23340844_ChIP-Seq_DLD1_Human1.47194176
50FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.46472304
51* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.46187406
52MYB_26560356_Chip-Seq_TH1_Human1.45806427
53SOX9_24532713_ChIP-Seq_HFSC_Mouse1.44543947
54ELF1_17652178_ChIP-ChIP_JURKAT_Human1.43394006
55ESR2_21235772_ChIP-Seq_MCF-7_Human1.39281464
56* BRD4_25478319_ChIP-Seq_HGPS_Human1.39029187
57SPI1_23127762_ChIP-Seq_K562_Human1.36934068
58SMAD_19615063_ChIP-ChIP_OVARY_Human1.34696639
59* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.33203604
60* SPI1_23547873_ChIP-Seq_NB4_Human1.29749630
61SCL_19346495_ChIP-Seq_HPC-7_Human1.28756985
62VDR_24787735_ChIP-Seq_THP-1_Human1.28487710
63KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.27971231
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.26775406
65SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24819028
66TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24399442
67TP53_18474530_ChIP-ChIP_U2OS_Human1.22655799
68PU_27001747_Chip-Seq_BMDM_Mouse1.20788278
69FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.20234869
70GATA3_26560356_Chip-Seq_TH2_Human1.18484681
71UBF1/2_26484160_Chip-Seq_HMECs_Human1.16894995
72SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.15439376
73* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15182413
74* MYB_26560356_Chip-Seq_TH2_Human1.14214523
75SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.12772136
76* ATF3_27146783_Chip-Seq_COLON_Human1.11660032
77* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.09190462
78GATA4_25053715_ChIP-Seq_YYC3_Human1.08964405
79VDR_24763502_ChIP-Seq_THP-1_Human1.07856792
80SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07706083
81ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06508254
82ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05959996
83HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05790760
84CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05685023
85* RUNX1_22412390_ChIP-Seq_EML_Mouse1.03856114
86* GATA3_27048872_Chip-Seq_THYMUS_Human1.02424244
87* TP63_23658742_ChIP-Seq_EP156T_Human0.99649435
88* UTX_26944678_Chip-Seq_JUKART_Human0.99263335
89CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97655693
90GATA3_24758297_ChIP-Seq_MCF-7_Human0.97397365
91ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96420687
92RACK7_27058665_Chip-Seq_MCF-7_Human0.96322579
93ZNF263_19887448_ChIP-Seq_K562_Human0.95483899
94* ELK1_22589737_ChIP-Seq_MCF10A_Human0.94611973
95PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94452789
96PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92592759
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.92568688
98TP53_16413492_ChIP-PET_HCT116_Human0.90504222
99FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.90349159
100MAF_26560356_Chip-Seq_TH1_Human0.90235429
101RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89957873
102PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.89850724
103* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89690974
104* KLF5_25053715_ChIP-Seq_YYC3_Human0.89635571
105NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89329588
106CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89155788
107MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.88749935
108FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.87485831
109STAT6_21828071_ChIP-Seq_BEAS2B_Human0.87283785
110WT1_19549856_ChIP-ChIP_CCG9911_Human0.86870888
111TFEB_21752829_ChIP-Seq_HELA_Human0.86808810
112CDX2_20551321_ChIP-Seq_CACO-2_Human0.85986022
113LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.84149013
114GATA2_22383799_ChIP-Seq_G1ME_Mouse0.82489615
115RXR_22108803_ChIP-Seq_LS180_Human0.82156091
116SMC1_22415368_ChIP-Seq_MEFs_Mouse0.82132701
117ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81687512
118* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81326542
119RUNX_20019798_ChIP-Seq_JUKART_Human0.81069574
120* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80937689
121SOX2_27498859_Chip-Seq_STOMACH_Mouse0.79582960

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.94140403
2MP0005275_abnormal_skin_tensile3.53836739
3MP0003436_decreased_susceptibility_to3.33638632
4MP0003705_abnormal_hypodermis_morpholog2.96493054
5MP0003566_abnormal_cell_adhesion2.80256162
6MP0009785_altered_susceptibility_to2.48853334
7MP0003303_peritoneal_inflammation2.42380542
8MP0003279_aneurysm2.36714851
9MP0002148_abnormal_hypersensitivity_rea2.36094952
10MP0001533_abnormal_skeleton_physiology2.30844572
11MP0005023_abnormal_wound_healing2.20005058
12MP0001958_emphysema2.18748076
13MP0002060_abnormal_skin_morphology2.18739608
14MP0001835_abnormal_antigen_presentation2.09815562
15MP0010352_gastrointestinal_tract_polyps2.08055878
16MP0005503_abnormal_tendon_morphology2.06820377
17* MP0002419_abnormal_innate_immunity2.04450721
18MP0003724_increased_susceptibility_to1.91669851
19MP0010234_abnormal_vibrissa_follicle1.81427415
20MP0002796_impaired_skin_barrier1.77578373
21MP0003453_abnormal_keratinocyte_physiol1.73879442
22MP0005000_abnormal_immune_tolerance1.70750968
23MP0003806_abnormal_nucleotide_metabolis1.69905261
24MP0000858_altered_metastatic_potential1.69658697
25MP0004947_skin_inflammation1.68727996
26MP0000343_altered_response_to1.67621479
27MP0005025_abnormal_response_to1.66840088
28MP0005390_skeleton_phenotype1.66354192
29MP0002877_abnormal_melanocyte_morpholog1.64415423
30MP0004272_abnormal_basement_membrane1.64319550
31MP0003448_altered_tumor_morphology1.62491263
32MP0002933_joint_inflammation1.61521988
33MP0001853_heart_inflammation1.60701146
34MP0002254_reproductive_system_inflammat1.59835008
35MP0006054_spinal_hemorrhage1.59093198
36MP0003941_abnormal_skin_development1.54945962
37MP0001216_abnormal_epidermal_layer1.51218726
38MP0003091_abnormal_cell_migration1.50184471
39MP0001542_abnormal_bone_strength1.48068267
40MP0005671_abnormal_response_to1.44144513
41MP0002405_respiratory_system_inflammati1.42774186
42MP0005164_abnormal_response_to1.42197841
43MP0009384_cardiac_valve_regurgitation1.40639436
44MP0000685_abnormal_immune_system1.40369358
45MP0003763_abnormal_thymus_physiology1.35181358
46* MP0002452_abnormal_antigen_presenting1.34382541
47MP0005165_increased_susceptibility_to1.34107738
48MP0001851_eye_inflammation1.33552950
49MP0009278_abnormal_bone_marrow1.33326876
50MP0006082_CNS_inflammation1.31937158
51MP0002282_abnormal_trachea_morphology1.31289722
52MP0000383_abnormal_hair_follicle1.31085083
53MP0008004_abnormal_stomach_pH1.30072627
54MP0005058_abnormal_lysosome_morphology1.28878598
55MP0002998_abnormal_bone_remodeling1.28154080
56MP0005387_immune_system_phenotype1.27621521
57MP0001790_abnormal_immune_system1.27621521
58MP0001243_abnormal_dermal_layer1.26056260
59MP0002396_abnormal_hematopoietic_system1.24613578
60MP0005076_abnormal_cell_differentiation1.24583494
61MP0009333_abnormal_splenocyte_physiolog1.23559104
62MP0001545_abnormal_hematopoietic_system1.23472104
63MP0005397_hematopoietic_system_phenotyp1.23472104
64MP0003950_abnormal_plasma_membrane1.21743476
65MP0009764_decreased_sensitivity_to1.19924003
66MP0003075_altered_response_to1.19097621
67MP0003300_gastrointestinal_ulcer1.17005345
68MP0003828_pulmonary_edema1.16900061
69MP0010678_abnormal_skin_adnexa1.16488878
70MP0005508_abnormal_skeleton_morphology1.15483435
71MP0004782_abnormal_surfactant_physiolog1.14511134
72MP0010155_abnormal_intestine_physiology1.14114401
73MP0005464_abnormal_platelet_physiology1.13020032
74MP0005501_abnormal_skin_physiology1.12678985
75MP0002723_abnormal_immune_serum1.10068870
76* MP0001819_abnormal_immune_cell1.09946089
77* MP0001845_abnormal_inflammatory_respons1.09752088
78MP0002295_abnormal_pulmonary_circulatio1.08036864
79* MP0002420_abnormal_adaptive_immunity1.07554263
80MP0010771_integument_phenotype1.07485175
81MP0003656_abnormal_erythrocyte_physiolo1.06180880
82MP0003795_abnormal_bone_structure1.05662905
83MP0004883_abnormal_blood_vessel1.05638225
84MP0008469_abnormal_protein_level1.04226104
85MP0000733_abnormal_muscle_development1.03922453
86MP0002098_abnormal_vibrissa_morphology1.03373766
87MP0005623_abnormal_meninges_morphology1.01217668
88MP0010368_abnormal_lymphatic_system0.98846448
89MP0000716_abnormal_immune_system0.97475051
90MP0001800_abnormal_humoral_immune0.97242088
91MP0005257_abnormal_intraocular_pressure0.96143970
92MP0002006_tumorigenesis0.95999063
93MP0005166_decreased_susceptibility_to0.95920929
94MP0002398_abnormal_bone_marrow0.95247009
95MP0001879_abnormal_lymphatic_vessel0.94935819
96MP0000249_abnormal_blood_vessel0.94217238
97MP0000377_abnormal_hair_follicle0.94002742
98MP0000465_gastrointestinal_hemorrhage0.93840040
99MP0003191_abnormal_cellular_cholesterol0.93815664
100MP0009763_increased_sensitivity_to0.92144587
101MP0003186_abnormal_redox_activity0.92109832
102MP0000762_abnormal_tongue_morphology0.91509893
103MP0001346_abnormal_lacrimal_gland0.89392700
104MP0002166_altered_tumor_susceptibility0.88746807
105MP0001191_abnormal_skin_condition0.86063591
106MP0000767_abnormal_smooth_muscle0.85994608
107MP0009931_abnormal_skin_appearance0.85133642
108MP0000681_abnormal_thyroid_gland0.84631919
109MP0009053_abnormal_anal_canal0.83182283
110MP0003045_fibrosis0.83175637
111MP0000467_abnormal_esophagus_morphology0.82838378
112MP0002332_abnormal_exercise_endurance0.81356179
113MP0008260_abnormal_autophagy0.81060461
114MP0002896_abnormal_bone_mineralization0.80662088
115MP0000163_abnormal_cartilage_morphology0.80546993
116MP0005388_respiratory_system_phenotype0.80350830
117MP0002113_abnormal_skeleton_development0.79378970
118MP0000427_abnormal_hair_cycle0.79063607
119MP0004808_abnormal_hematopoietic_stem0.79045885
120MP0002429_abnormal_blood_cell0.78729918
121MP0000627_abnormal_mammary_gland0.77883188
122MP0002115_abnormal_skeleton_extremities0.77645950
123MP0002133_abnormal_respiratory_system0.75237586
124MP0002722_abnormal_immune_system0.74294816

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)4.75057125
2Recurrent abscess formation (HP:0002722)4.46587831
3Premature rupture of membranes (HP:0001788)4.45075921
4Protrusio acetabuli (HP:0003179)3.99749160
5Recurrent gram-negative bacterial infections (HP:0005420)3.74090584
6Recurrent bacterial skin infections (HP:0005406)3.69686511
7Cervical subluxation (HP:0003308)3.67807519
8Atrophic scars (HP:0001075)3.60471387
9Osteolytic defects of the hand bones (HP:0009699)3.39430619
10Osteolytic defects of the phalanges of the hand (HP:0009771)3.39430619
11Abnormality of liposaccharide metabolism (HP:0010968)3.30496665
12Abnormality of glycosphingolipid metabolism (HP:0004343)3.30496665
13Abnormality of glycolipid metabolism (HP:0010969)3.30496665
14Vertebral compression fractures (HP:0002953)3.22358790
15Peritonitis (HP:0002586)3.10753420
16Abnormality of macrophages (HP:0004311)3.09459244
17Amyloidosis (HP:0011034)2.82696208
18Vacuolated lymphocytes (HP:0001922)2.79559590
19Right ventricular cardiomyopathy (HP:0011663)2.79433395
20Interstitial pulmonary disease (HP:0006530)2.74872778
21Autoimmune hemolytic anemia (HP:0001890)2.73528481
22Aortic dissection (HP:0002647)2.68036345
23Epiphyseal dysplasia (HP:0002656)2.65902359
24Thick nail (HP:0001805)2.65205887
25Dilatation of the ascending aorta (HP:0005111)2.61619211
26Reduced subcutaneous adipose tissue (HP:0003758)2.60522742
27Pulmonary infiltrates (HP:0002113)2.57804833
28Aortic aneurysm (HP:0004942)2.55148065
29Gingivitis (HP:0000230)2.53157746
30Wormian bones (HP:0002645)2.52811643
31Neonatal short-limb short stature (HP:0008921)2.51014978
32Increased cerebral lipofuscin (HP:0011813)2.48533932
33Glucose intolerance (HP:0000833)2.48147608
34Distal lower limb muscle weakness (HP:0009053)2.46326393
35Mediastinal lymphadenopathy (HP:0100721)2.44617981
36Pustule (HP:0200039)2.42829962
37Oral leukoplakia (HP:0002745)2.41845643
38Absent frontal sinuses (HP:0002688)2.41656443
39Stomatitis (HP:0010280)2.40459773
40Lip pit (HP:0100267)2.40100133
41Cupped ribs (HP:0000887)2.34059024
42Myositis (HP:0100614)2.33981116
43Short nail (HP:0001799)2.32991749
44Onycholysis (HP:0001806)2.32950521
45Abnormality of the distal phalanges of the toes (HP:0010182)2.32626691
46Milia (HP:0001056)2.32589094
47Beaking of vertebral bodies (HP:0004568)2.31699939
48Obstructive lung disease (HP:0006536)2.31336093
49Chronic obstructive pulmonary disease (HP:0006510)2.31336093
50Soft skin (HP:0000977)2.30448084
51Syringomyelia (HP:0003396)2.29433299
52Spinal cord lesions (HP:0100561)2.29433299
53Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.28253949
54Increased neuronal autofluorescent lipopigment (HP:0002074)2.27841508
55Vascular tortuosity (HP:0004948)2.23673983
56Fragile skin (HP:0001030)2.23281188
57Nail dystrophy (HP:0008404)2.23006845
58Increased connective tissue (HP:0009025)2.22067100
59Plantar hyperkeratosis (HP:0007556)2.21798704
60Orchitis (HP:0100796)2.20835179
61Cellulitis (HP:0100658)2.20552747
62Xerostomia (HP:0000217)2.20225664
63Spondylolisthesis (HP:0003302)2.19974998
64Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.19760061
65Fragile nails (HP:0001808)2.18065507
66Spinal rigidity (HP:0003306)2.17600605
67Abnormality of T cell number (HP:0011839)2.16707556
68Abnormality of nail color (HP:0100643)2.16631813
69Cerebral aneurysm (HP:0004944)2.15322621
70Myocardial infarction (HP:0001658)2.14871887
71Increased IgE level (HP:0003212)2.13667528
72Ankle contracture (HP:0006466)2.13079805
73Dysostosis multiplex (HP:0000943)2.12053464
74Erythema (HP:0010783)2.10746004
75Fatigue (HP:0012378)2.09738404
76Hypergammaglobulinemia (HP:0010702)2.08838248
77Abnormality of the frontal sinuses (HP:0002687)2.08652359
78Glomerulopathy (HP:0100820)2.06838774
79T lymphocytopenia (HP:0005403)2.06082650
80Follicular hyperkeratosis (HP:0007502)2.03270690
81Elevated erythrocyte sedimentation rate (HP:0003565)2.03115438
82Alopecia of scalp (HP:0002293)2.02962941
83Natal tooth (HP:0000695)1.99144180
84Coxa vara (HP:0002812)1.98212212
85Keratoconjunctivitis sicca (HP:0001097)1.98080653
86Abnormal delayed hypersensitivity skin test (HP:0002963)1.98028418
87Retrobulbar optic neuritis (HP:0100654)1.97779237
88Optic neuritis (HP:0100653)1.97779237
89Urticaria (HP:0001025)1.96181372
90Arterial tortuosity (HP:0005116)1.96026661
91Thrombocytosis (HP:0001894)1.94652303
92Palmar hyperkeratosis (HP:0010765)1.94540326
93Flat acetabular roof (HP:0003180)1.94240029
94Axonal loss (HP:0003447)1.94091499
95Blue sclerae (HP:0000592)1.93885082
96Gangrene (HP:0100758)1.93575113
97Recurrent skin infections (HP:0001581)1.93567799
98Metaphyseal dysplasia (HP:0100255)1.92918717
99Ulnar bowing (HP:0003031)1.92871755
100Abnormal blistering of the skin (HP:0008066)1.91846035
101Periodontitis (HP:0000704)1.90145923
102Autoimmune thrombocytopenia (HP:0001973)1.89051268
103Skin ulcer (HP:0200042)1.88666619
104Joint stiffness (HP:0001387)1.85749041
105Delayed closure of the anterior fontanelle (HP:0001476)1.84629678
106Recurrent viral infections (HP:0004429)1.84453182
107Hematochezia (HP:0002573)1.84310856
108Disinhibition (HP:0000734)1.84083726
109Shallow orbits (HP:0000586)1.82591235
110Biconcave vertebral bodies (HP:0004586)1.82260345
111Abnormality of the nasal mucosa (HP:0000433)1.81298480
112Platyspondyly (HP:0000926)1.80670352
113Radial bowing (HP:0002986)1.80475221
114Loss of speech (HP:0002371)1.79443993
115Elbow flexion contracture (HP:0002987)1.79343657
116Granulocytopenia (HP:0001913)1.78900708
117Nuclear cataract (HP:0100018)1.78477238
118Nasal polyposis (HP:0100582)1.78183225
119Short middle phalanx of the 5th finger (HP:0004220)1.78013424
120Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.77752368
121Abnormality of the acetabulum (HP:0003170)1.77588322
122Vasculitis (HP:0002633)1.77470977
123Arterial thrombosis (HP:0004420)1.76175833
124Keratoconjunctivitis (HP:0001096)1.76124922
125Increased IgM level (HP:0003496)1.75996773
126Chronic mucocutaneous candidiasis (HP:0002728)1.75662948
127Recurrent cutaneous fungal infections (HP:0011370)1.75662948
128Subacute progressive viral hepatitis (HP:0006572)1.75441048
129Osteomyelitis (HP:0002754)1.75261888
130Gastrointestinal infarctions (HP:0005244)1.74402809
131Hemoptysis (HP:0002105)1.72811923
132Abnormal foot bone ossification (HP:0010675)1.72721594
133Hepatosplenomegaly (HP:0001433)1.72131582
134Increased density of long bones (HP:0006392)1.71969096
135Palmoplantar hyperkeratosis (HP:0000972)1.71967153
136Abnormality of the odontoid process (HP:0003310)1.71929250
137Abnormality of T cell physiology (HP:0011840)1.71718952
138Recurrent fungal infections (HP:0002841)1.71706473
139Increased mean platelet volume (HP:0011877)1.70579877
140Systemic lupus erythematosus (HP:0002725)1.70183066
141Parakeratosis (HP:0001036)1.69389355
142Abnormality of the lumbar spine (HP:0100712)1.68231284
143Hypoplasia of the odontoid process (HP:0003311)1.67956062
144Abnormal vertebral ossification (HP:0100569)1.67128483
145Anhidrosis (HP:0000970)1.66674258
146Abnormal platelet volume (HP:0011876)1.66471567
147Abnormality of the pericardium (HP:0001697)1.65422719
148Ulnar deviation of the wrist (HP:0003049)1.65290329
149Spinal cord compression (HP:0002176)1.64626821
150Femoral bowing (HP:0002980)1.63405157
151Abnormality of dentin (HP:0010299)1.62932731

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK13.47464427
2MAP3K32.82075526
3EPHA22.81067287
4MST42.74980753
5PBK2.50979483
6PIM22.44104956
7MST1R2.40174859
8MAP3K142.34056349
9TTN2.32820650
10ERN12.31743082
11LIMK12.22560957
12BLK1.99617131
13STK101.96754716
14GRK71.95610729
15TBK11.95420547
16LRRK21.93676694
17NEK91.93258927
18DDR21.93087961
19SIK31.93042824
20RIPK41.89374344
21SCYL21.88657506
22IRAK41.86128217
23RPS6KA41.84610557
24NME21.83817434
25EPHB21.68502092
26TRIB31.65023401
27TAOK31.60201257
28TGFBR21.56819343
29FLT31.54959441
30MAP2K31.53958466
31TYK21.46734142
32PIK3CG1.41066715
33EPHB11.39791135
34PTK21.35689483
35FRK1.34990534
36MOS1.34684558
37CSK1.31013015
38IKBKB1.28122425
39FER1.26621898
40TXK1.23183776
41MAPKAPK31.21747070
42TESK21.21480521
43EIF2AK31.21097026
44PRPF4B1.19999606
45BMX1.19837136
46TEC1.16448785
47IRAK31.13756680
48PTK61.12836290
49ERBB41.08048049
50MAP3K111.07239492
51PAK41.06626599
52MET1.05415722
53JAK31.05358675
54EPHA31.05305872
55PRKG21.01987803
56LATS11.01858663
57RIPK11.01118714
58IKBKE0.99489004
59ABL20.98311886
60CDK80.95355129
61FES0.95180982
62MAP3K60.91778844
63KIT0.90856449
64BTK0.89211778
65STK30.88285826
66JAK10.83692779
67GRK60.81009275
68MAP2K10.80871403
69MAPKAPK50.75088215
70MAP3K120.74808582
71BMPR1B0.74767689
72ZAP700.74619910
73MAPKAPK20.74255495
74MAP3K130.72719987
75TGFBR10.72666965
76CHUK0.72127163
77PDGFRA0.70239305
78FGR0.69765316
79MAPK150.69493661
80MAP3K20.68192104
81DMPK0.67520135
82* HCK0.67361171
83ILK0.66862526
84RPS6KB20.66344026
85KDR0.66061523
86PKN20.65948800
87LCK0.65501060
88PIK3CA0.65407545
89PAK20.64807801
90NUAK10.64320863
91SYK0.60183271
92MYLK0.60115329
93EIF2AK20.59157567
94TAOK10.58746695
95PIM10.58121580
96CDK60.56413675
97PRKCD0.56184768
98STK240.56089164
99BMPR20.55728647
100TAOK20.54969798
101FGFR30.54662856
102ROCK10.54059006
103PAK30.54020830
104MAPK70.53865937
105* TRPM70.53129984
106ITK0.53032420
107* ABL10.51765437
108CSF1R0.51260335
109JAK20.50836824
110PTK2B0.50796654
111MAP3K10.50483565
112PDGFRB0.50363073
113MATK0.50198714
114ZAK0.50096103
115* IGF1R0.46120544
116MAP3K80.45839876
117LATS20.45365637
118MAP4K10.45346686
119STK40.44065551
120FGFR10.42959713
121CLK10.41612795
122EIF2AK10.40868229
123LYN0.40796034
124GSK3A0.40210346
125NTRK10.39287426
126MAP3K50.38963275
127BCR0.38743477
128PAK10.37405585
129ROCK20.36969305

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.85888818
2Malaria_Homo sapiens_hsa051442.39138278
3Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.34858511
4Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.16626606
5ECM-receptor interaction_Homo sapiens_hsa045122.13509285
6Phagosome_Homo sapiens_hsa041452.07242959
7Pertussis_Homo sapiens_hsa051332.05761157
8Leukocyte transendothelial migration_Homo sapiens_hsa046701.98893269
9Shigellosis_Homo sapiens_hsa051311.94037581
10Legionellosis_Homo sapiens_hsa051341.92882108
11Toll-like receptor signaling pathway_Homo sapiens_hsa046201.91334471
12Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.90450742
13Osteoclast differentiation_Homo sapiens_hsa043801.84750677
14Tuberculosis_Homo sapiens_hsa051521.79544627
15Salmonella infection_Homo sapiens_hsa051321.77862885
16Staphylococcus aureus infection_Homo sapiens_hsa051501.77244591
17Type I diabetes mellitus_Homo sapiens_hsa049401.75741223
18TNF signaling pathway_Homo sapiens_hsa046681.75354159
19Rheumatoid arthritis_Homo sapiens_hsa053231.71060821
20Amoebiasis_Homo sapiens_hsa051461.70968119
21Lysosome_Homo sapiens_hsa041421.66805891
22Toxoplasmosis_Homo sapiens_hsa051451.62366687
23Proteoglycans in cancer_Homo sapiens_hsa052051.60212727
24Focal adhesion_Homo sapiens_hsa045101.56887878
25NF-kappa B signaling pathway_Homo sapiens_hsa040641.54927562
26AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.54322094
27Adherens junction_Homo sapiens_hsa045201.53398643
28Viral myocarditis_Homo sapiens_hsa054161.46439080
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.44493381
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.44385595
31Apoptosis_Homo sapiens_hsa042101.43128979
32Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.42912799
33Bladder cancer_Homo sapiens_hsa052191.39014966
34Hematopoietic cell lineage_Homo sapiens_hsa046401.37660542
35Other glycan degradation_Homo sapiens_hsa005111.35958089
36Glycosaminoglycan degradation_Homo sapiens_hsa005311.34503731
37Graft-versus-host disease_Homo sapiens_hsa053321.32341758
38Proteasome_Homo sapiens_hsa030501.31221507
39Small cell lung cancer_Homo sapiens_hsa052221.26251839
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.26162197
41RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.17040467
42Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.15876697
43Platelet activation_Homo sapiens_hsa046111.15834255
44T cell receptor signaling pathway_Homo sapiens_hsa046601.15769285
45Measles_Homo sapiens_hsa051621.12903024
46p53 signaling pathway_Homo sapiens_hsa041151.12748200
47Influenza A_Homo sapiens_hsa051641.12287582
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11657712
49Allograft rejection_Homo sapiens_hsa053301.07304917
50Jak-STAT signaling pathway_Homo sapiens_hsa046301.05355541
51Regulation of actin cytoskeleton_Homo sapiens_hsa048101.04982965
52Hepatitis B_Homo sapiens_hsa051611.04382319
53Asthma_Homo sapiens_hsa053101.01846386
54Sphingolipid metabolism_Homo sapiens_hsa006000.99177117
55TGF-beta signaling pathway_Homo sapiens_hsa043500.98469094
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.97720487
57Arachidonic acid metabolism_Homo sapiens_hsa005900.93879090
58Chemokine signaling pathway_Homo sapiens_hsa040620.93538741
59Pancreatic cancer_Homo sapiens_hsa052120.92709523
60Primary immunodeficiency_Homo sapiens_hsa053400.90504650
61MicroRNAs in cancer_Homo sapiens_hsa052060.90069995
62Chronic myeloid leukemia_Homo sapiens_hsa052200.88180288
63Glutathione metabolism_Homo sapiens_hsa004800.86267042
64Antigen processing and presentation_Homo sapiens_hsa046120.86061046
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.84555761
66B cell receptor signaling pathway_Homo sapiens_hsa046620.83127930
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81919914
68Hepatitis C_Homo sapiens_hsa051600.77251175
69Caffeine metabolism_Homo sapiens_hsa002320.76489596
70Autoimmune thyroid disease_Homo sapiens_hsa053200.75611294
71SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74497228
72Herpes simplex infection_Homo sapiens_hsa051680.74257116
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.72937673
74VEGF signaling pathway_Homo sapiens_hsa043700.71457318
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70028762
76Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67962009
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.67921070
78Vibrio cholerae infection_Homo sapiens_hsa051100.66191680
79Sulfur metabolism_Homo sapiens_hsa009200.65891995
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65524985
81Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.64972674
82PI3K-Akt signaling pathway_Homo sapiens_hsa041510.64337436
83Acute myeloid leukemia_Homo sapiens_hsa052210.63514084
84HIF-1 signaling pathway_Homo sapiens_hsa040660.61601884
85African trypanosomiasis_Homo sapiens_hsa051430.59287951
86Hippo signaling pathway_Homo sapiens_hsa043900.59236668
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.58209755
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58132727
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.58093018
90Endocytosis_Homo sapiens_hsa041440.56947177
91Epstein-Barr virus infection_Homo sapiens_hsa051690.56855130
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.56184853
93HTLV-I infection_Homo sapiens_hsa051660.55286768
94Viral carcinogenesis_Homo sapiens_hsa052030.54896188
95Rap1 signaling pathway_Homo sapiens_hsa040150.54682243
96Melanoma_Homo sapiens_hsa052180.54094975
97Chemical carcinogenesis_Homo sapiens_hsa052040.53245523
98Renal cell carcinoma_Homo sapiens_hsa052110.52727449
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.52027992
100Pathways in cancer_Homo sapiens_hsa052000.50873355
101Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50552894
102Mineral absorption_Homo sapiens_hsa049780.49708828
103Complement and coagulation cascades_Homo sapiens_hsa046100.49191450
104Protein digestion and absorption_Homo sapiens_hsa049740.48567582
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47794972
106Tight junction_Homo sapiens_hsa045300.46913876
107Non-small cell lung cancer_Homo sapiens_hsa052230.45804276
108Thyroid cancer_Homo sapiens_hsa052160.44202236
109Histidine metabolism_Homo sapiens_hsa003400.41873048
110Prostate cancer_Homo sapiens_hsa052150.40715462
111Pentose phosphate pathway_Homo sapiens_hsa000300.38539637
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34558788
113Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29495977
114Galactose metabolism_Homo sapiens_hsa000520.27152924
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.27043719

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