ANXA10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The function of this gene has not yet been determined. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1extracellular fibril organization (GO:0043206)9.69949855
2O-glycan processing (GO:0016266)8.50888687
3fibril organization (GO:0097435)8.35156978
4digestive system process (GO:0022600)8.18101914
5glutathione derivative metabolic process (GO:1901685)8.13805956
6glutathione derivative biosynthetic process (GO:1901687)8.13805956
7response to iron ion (GO:0010039)7.80036208
8protein autoprocessing (GO:0016540)7.74401386
9sulfation (GO:0051923)7.63883605
10bundle of His cell to Purkinje myocyte communication (GO:0086069)7.09134966
11regulation of proton transport (GO:0010155)6.65903381
12negative regulation of transcription by competitive promoter binding (GO:0010944)6.53055410
13purine ribonucleoside bisphosphate metabolic process (GO:0034035)6.34158775
143-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)6.34158775
15glandular epithelial cell differentiation (GO:0002067)6.32820895
16kidney morphogenesis (GO:0060993)6.11435950
17negative regulation of digestive system process (GO:0060457)6.04246453
18protein O-linked glycosylation (GO:0006493)5.95280353
19polyketide metabolic process (GO:0030638)5.89640768
20doxorubicin metabolic process (GO:0044598)5.89640768
21daunorubicin metabolic process (GO:0044597)5.89640768
22intestinal absorption (GO:0050892)5.69230753
23uronic acid metabolic process (GO:0006063)5.38117877
24glucuronate metabolic process (GO:0019585)5.38117877
25negative regulation of epidermal cell differentiation (GO:0045605)5.29772905
26aminoglycoside antibiotic metabolic process (GO:0030647)5.21250752
27production of molecular mediator of immune response (GO:0002440)5.16967597
28fucose catabolic process (GO:0019317)4.96313803
29L-fucose metabolic process (GO:0042354)4.96313803
30L-fucose catabolic process (GO:0042355)4.96313803
31thyroid hormone metabolic process (GO:0042403)4.90885469
32calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.76656487
33regulation of phospholipase A2 activity (GO:0032429)4.36831212
34phosphatidylserine acyl-chain remodeling (GO:0036150)4.34239060
35phospholipid scrambling (GO:0017121)4.31625079
36thyroid hormone generation (GO:0006590)4.27693866
37glutathione metabolic process (GO:0006749)4.24835365
38positive regulation of translational initiation (GO:0045948)4.24460498
39dicarboxylic acid biosynthetic process (GO:0043650)4.24063375
40epithelial cell fate commitment (GO:0072148)4.21174862
41sulfur amino acid catabolic process (GO:0000098)4.16891991
42cobalamin metabolic process (GO:0009235)4.15771663
43citrulline biosynthetic process (GO:0019240)4.12454641
44ventricular cardiac muscle cell action potential (GO:0086005)3.98191644
45negative regulation of epidermis development (GO:0045683)3.96594699
46regulation of pH (GO:0006885)3.95037465
47lung secretory cell differentiation (GO:0061140)3.88097230
48exogenous drug catabolic process (GO:0042738)3.85985006
49epoxygenase P450 pathway (GO:0019373)3.85801661
50protein localization to microtubule (GO:0035372)3.83411101
51primary alcohol catabolic process (GO:0034310)3.78753621
52phosphatidylserine metabolic process (GO:0006658)3.78520316
53xenobiotic metabolic process (GO:0006805)3.77861891
54intestinal epithelial cell development (GO:0060576)3.76226028
55regulation of fibrinolysis (GO:0051917)3.74337655
56drug catabolic process (GO:0042737)3.72149862
57L-phenylalanine metabolic process (GO:0006558)3.70626709
58erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.70626709
59nitric oxide biosynthetic process (GO:0006809)3.65611521
60diacylglycerol metabolic process (GO:0046339)3.64320949
61regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.63210052
62glutamate metabolic process (GO:0006536)3.62774260
63embryonic retina morphogenesis in camera-type eye (GO:0060059)3.62740313
64intestinal cholesterol absorption (GO:0030299)3.58600754
65myelin maintenance (GO:0043217)3.58180571
66potassium ion export (GO:0071435)3.56674167
67regulation of transforming growth factor beta2 production (GO:0032909)3.54161653
68leukotriene metabolic process (GO:0006691)3.52420854
69receptor recycling (GO:0001881)3.51461642
70omega-hydroxylase P450 pathway (GO:0097267)3.51346258
71cytoskeletal anchoring at plasma membrane (GO:0007016)3.49376303
72glycoside metabolic process (GO:0016137)3.48918698
73retinal metabolic process (GO:0042574)3.48913683
74Golgi to endosome transport (GO:0006895)3.47831421
75embryonic foregut morphogenesis (GO:0048617)3.44593557
76positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.42989582
77regulation of keratinocyte proliferation (GO:0010837)3.42367806
78L-phenylalanine catabolic process (GO:0006559)3.41892463
79erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.41892463
80tight junction assembly (GO:0070830)3.41041899
81cellular response to oxygen radical (GO:0071450)3.38631074
82removal of superoxide radicals (GO:0019430)3.38631074
83cellular response to superoxide (GO:0071451)3.38631074
84fibrinolysis (GO:0042730)3.38158030
85cellular ketone body metabolic process (GO:0046950)3.37829804
86regulation of cardioblast differentiation (GO:0051890)3.35367725
87cyclooxygenase pathway (GO:0019371)3.34013648
88regulation of protein activation cascade (GO:2000257)3.33826765
89Golgi transport vesicle coating (GO:0048200)3.33277358
90COPI coating of Golgi vesicle (GO:0048205)3.33277358
91regulation of keratinocyte differentiation (GO:0045616)3.33190559
92cellular response to gonadotropin stimulus (GO:0071371)3.32835883
93phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.32395752
94negative regulation of fibrinolysis (GO:0051918)3.32269096
95cellular response to arsenic-containing substance (GO:0071243)3.31307562
96succinate metabolic process (GO:0006105)3.30924474
97nucleotide transmembrane transport (GO:1901679)3.29949533
98phosphatidylinositol acyl-chain remodeling (GO:0036149)3.26214094
99regulation of heart rate by cardiac conduction (GO:0086091)3.25285759
100hepatocyte apoptotic process (GO:0097284)3.24600452
101regulation of complement activation (GO:0030449)3.22094421
102peptidyl-cysteine modification (GO:0018198)3.20648855
103leukotriene biosynthetic process (GO:0019370)3.20405828
104regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.19923640
105endocrine pancreas development (GO:0031018)3.19780360
106positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.18427009
107ethanol metabolic process (GO:0006067)3.18044546
108alditol phosphate metabolic process (GO:0052646)3.16448724
109pH reduction (GO:0045851)3.14578967
110atrioventricular valve morphogenesis (GO:0003181)3.14543706
111phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.14050842
112heart trabecula formation (GO:0060347)3.13442258
113negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.13410174
114regulation of type B pancreatic cell apoptotic process (GO:2000674)3.13064231
115protein retention in ER lumen (GO:0006621)3.11434066
116positive regulation of gluconeogenesis (GO:0045722)3.10486291
117sodium ion export (GO:0071436)3.07022672
118interleukin-1-mediated signaling pathway (GO:0070498)3.06889750
119columnar/cuboidal epithelial cell differentiation (GO:0002065)3.06593546
120L-serine transport (GO:0015825)3.06363761
121maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.06351667
122hormone catabolic process (GO:0042447)3.04692641
123glutamine family amino acid biosynthetic process (GO:0009084)3.01136982
124regulation of transforming growth factor beta1 production (GO:0032908)3.01078806
125icosanoid transport (GO:0071715)2.99066310
126fatty acid derivative transport (GO:1901571)2.99066310
127type B pancreatic cell development (GO:0003323)2.98022928
128nucleoside bisphosphate metabolic process (GO:0033865)2.95805965
129purine nucleoside bisphosphate metabolic process (GO:0034032)2.95805965
130ribonucleoside bisphosphate metabolic process (GO:0033875)2.95805965
131dicarboxylic acid catabolic process (GO:0043649)2.94880481
132nucleotide-sugar biosynthetic process (GO:0009226)2.94676617
133embryonic digestive tract morphogenesis (GO:0048557)2.94661587
134bile acid metabolic process (GO:0008206)2.94562337
135response to superoxide (GO:0000303)2.94460143
136columnar/cuboidal epithelial cell development (GO:0002066)2.94157632
137cellular aldehyde metabolic process (GO:0006081)2.93764592
138glyoxylate metabolic process (GO:0046487)2.92040345
139primary alcohol metabolic process (GO:0034308)2.91498988
140cell communication involved in cardiac conduction (GO:0086065)2.90510586
141desmosome organization (GO:0002934)2.90508072
142ketone body metabolic process (GO:1902224)2.89868340
143fucose metabolic process (GO:0006004)2.88035687
144opsonization (GO:0008228)2.87221251
145phenylpropanoid metabolic process (GO:0009698)2.86374234
146positive regulation of glycolytic process (GO:0045821)2.86101441
147ethanol oxidation (GO:0006069)2.85740235
148hemidesmosome assembly (GO:0031581)2.85499109
149acid secretion (GO:0046717)2.84977853
150macroautophagy (GO:0016236)2.84666481
151acrosome reaction (GO:0007340)2.83943415
152flavonoid metabolic process (GO:0009812)2.83380934
153negative regulation of hormone metabolic process (GO:0032351)2.82290034
154cardiac conduction (GO:0061337)2.82245198
155sphingomyelin metabolic process (GO:0006684)2.80795295
156regulation of macrophage activation (GO:0043030)2.80115502
157bile acid and bile salt transport (GO:0015721)2.79775248
158negative regulation of protein activation cascade (GO:2000258)2.74229437
159morphogenesis of an epithelial fold (GO:0060571)2.74174281
160drug metabolic process (GO:0017144)2.73643889
161response to oxygen radical (GO:0000305)2.72166217
162negative regulation of fatty acid biosynthetic process (GO:0045717)2.72044923
163regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.71639565
164heparin metabolic process (GO:0030202)2.71207485
165heparin biosynthetic process (GO:0030210)2.71207485
166arachidonic acid secretion (GO:0050482)2.70973388
167icosanoid secretion (GO:0032309)2.70973388
168labyrinthine layer blood vessel development (GO:0060716)2.70861143
169keratinocyte development (GO:0003334)2.69668652
170alternative mRNA splicing, via spliceosome (GO:0000380)2.68825502
171serine transport (GO:0032329)2.68390054
172response to gonadotropin (GO:0034698)2.65456087
173cellular glucuronidation (GO:0052695)2.65413825
174epithelial cell-cell adhesion (GO:0090136)2.62217268
175monovalent inorganic cation homeostasis (GO:0055067)2.60880567
176epithelial cell differentiation involved in prostate gland development (GO:0060742)2.59717891
177growth hormone secretion (GO:0030252)2.59194773
178hexose catabolic process (GO:0019320)2.58761562
179lung cell differentiation (GO:0060479)2.56400205
180hypotonic response (GO:0006971)2.52689450
181regulation of skeletal muscle contraction (GO:0014819)2.51962192
182maintenance of gastrointestinal epithelium (GO:0030277)18.1645581
183epithelial structure maintenance (GO:0010669)13.5754713
184digestion (GO:0007586)10.5780310

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_15608294_ChIP-ChIP_MCF-7_Human6.75851500
2* SOX2_27498859_Chip-Seq_STOMACH_Mouse5.81149928
3ESR1_21235772_ChIP-Seq_MCF-7_Human3.98537290
4STAT6_21828071_ChIP-Seq_BEAS2B_Human3.84514211
5ESR2_21235772_ChIP-Seq_MCF-7_Human3.66537489
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.03341178
7* GATA4_25053715_ChIP-Seq_YYC3_Human3.00785757
8EGR1_23403033_ChIP-Seq_LIVER_Mouse2.95782878
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.84057961
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.74136002
11HIF1A_21447827_ChIP-Seq_MCF-7_Human2.65610104
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.61792671
13PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.58383577
14PPAR_26484153_Chip-Seq_NCI-H1993_Human2.57778497
15* SOX2_20726797_ChIP-Seq_SW620_Human2.55905123
16ESR1_20079471_ChIP-ChIP_T-47D_Human2.54520981
17TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.51155760
18SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.49947342
19RARG_19884340_ChIP-ChIP_MEFs_Mouse2.49485443
20GATA6_25053715_ChIP-Seq_YYC3_Human2.48069984
21TRIM28_21343339_ChIP-Seq_HEK293_Human2.34946398
22CDX2_20551321_ChIP-Seq_CACO-2_Human2.33230748
23FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.17761719
24HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.12851052
25* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.01597092
26PPARA_22158963_ChIP-Seq_LIVER_Mouse1.93305447
27AHR_22903824_ChIP-Seq_MCF-7_Human1.89485802
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.87079707
29FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.80920844
30VDR_22108803_ChIP-Seq_LS180_Human1.74393694
31KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.72420816
32SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.70913340
33SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.70913340
34* KLF5_25053715_ChIP-Seq_YYC3_Human1.68463596
35LXR_22158963_ChIP-Seq_LIVER_Mouse1.67136034
36KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.66695707
37GATA3_24758297_ChIP-Seq_MCF-7_Human1.66199759
38IGF1R_20145208_ChIP-Seq_DFB_Human1.65563911
39IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.64361227
40RXR_22158963_ChIP-Seq_LIVER_Mouse1.64279748
41PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.63238194
42RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61926796
43FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.61493683
44ZNF217_24962896_ChIP-Seq_MCF-7_Human1.59829312
45HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.59639276
46STAT1_20625510_ChIP-Seq_HELA_Human1.58836607
47SRY_22984422_ChIP-ChIP_TESTIS_Rat1.58632056
48AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.57740351
49MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.57075696
50ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.56981257
51RUNX1_27514584_Chip-Seq_MCF-7_Human1.52478476
52RACK7_27058665_Chip-Seq_MCF-7_Human1.45461932
53FOXO3_23340844_ChIP-Seq_DLD1_Human1.44572515
54P63_26484246_Chip-Seq_KERATINOCYTES_Human1.44234227
55LXR_22292898_ChIP-Seq_THP-1_Human1.43806610
56SMAD_19615063_ChIP-ChIP_OVARY_Human1.43606585
57EGR1_19032775_ChIP-ChIP_M12_Human1.40979259
58AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37697340
59RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.37608134
60NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.34579199
61HNF4A_19822575_ChIP-Seq_HepG2_Human1.34250888
62CTNNB1_20460455_ChIP-Seq_HCT116_Human1.31960548
63ZNF263_19887448_ChIP-Seq_K562_Human1.29230048
64STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.29224271
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27342414
66* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.26840412
67CLOCK_20551151_ChIP-Seq_293T_Human1.26159637
68FOXA2_19822575_ChIP-Seq_HepG2_Human1.24245297
69* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22880639
70RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.20881097
71SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19626383
72ARNT_22903824_ChIP-Seq_MCF-7_Human1.19406848
73FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19302041
74* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.18760364
75ZNF274_21170338_ChIP-Seq_K562_Hela1.18376454
76ATF3_27146783_Chip-Seq_COLON_Human1.17886551
77CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.17085451
78HTT_18923047_ChIP-ChIP_STHdh_Human1.16043040
79TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.15891821
80FLI1_27457419_Chip-Seq_LIVER_Mouse1.14234254
81CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13504006
82SALL4_18804426_ChIP-ChIP_XEN_Mouse1.12799417
83GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12239781
84PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.11735399
85NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11386652
86* TP63_23658742_ChIP-Seq_EP156T_Human1.10578813
87ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10090486
88RXR_22108803_ChIP-Seq_LS180_Human1.09517783
89CJUN_26792858_Chip-Seq_BT549_Human1.09158233
90NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.07626337
91BCAT_22108803_ChIP-Seq_LS180_Human1.06923150
92TCF4_18268006_ChIP-ChIP_LS174T_Human1.06256081
93ELK4_26923725_Chip-Seq_MESODERM_Mouse1.05095155
94PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.04835571
95PIAS1_25552417_ChIP-Seq_VCAP_Human1.02736413
96SOX9_24532713_ChIP-Seq_HFSC_Mouse1.00573737
97TCF4_22108803_ChIP-Seq_LS180_Human0.98822813
98Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.98163438
99KDM2B_26808549_Chip-Seq_K562_Human0.97043115
100FOXA1_25329375_ChIP-Seq_VCAP_Human0.95271632
101FOXA1_27270436_Chip-Seq_PROSTATE_Human0.95271632
102GATA2_21666600_ChIP-Seq_HMVEC_Human0.95236553
103FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.94521609
104FOXA1_25552417_ChIP-Seq_VCAP_Human0.94218698
105BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94111846
106* EP300_21415370_ChIP-Seq_HL-1_Mouse0.90944879
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88422562
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.87914329
109NRF2_20460467_ChIP-Seq_MEFs_Mouse0.87914329
110FOXH1_21741376_ChIP-Seq_EPCs_Human0.86602585
111CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.86477157
112TP53_18474530_ChIP-ChIP_U2OS_Human0.83611851
113PCGF2_27294783_Chip-Seq_ESCs_Mouse0.82278563
114SUZ12_18555785_Chip-Seq_ESCs_Mouse0.81606341
115TBX20_22080862_ChIP-Seq_HEART_Mouse0.80728597
116TBX20_22328084_ChIP-Seq_HEART_Mouse0.80728597
117NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.78848940
118CEBPB_22108803_ChIP-Seq_LS180_Human0.78607005
119CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.77820669
120SMAD4_21741376_ChIP-Seq_HESCs_Human0.77407432
121AR_21909140_ChIP-Seq_LNCAP_Human0.76727525
122SMAD1_18555785_Chip-Seq_ESCs_Mouse0.76682437
123P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.76036302
124TP53_16413492_ChIP-PET_HCT116_Human0.75559581
125DNAJC2_21179169_ChIP-ChIP_NT2_Human0.75426282
126EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.75420832
127TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75092949
128NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.74983333
129CREB1_26743006_Chip-Seq_LNCaP_Human0.74176859
130BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.73724981
131CDX2_22108803_ChIP-Seq_LS180_Human0.73071008
132MYC_19829295_ChIP-Seq_ESCs_Human0.72740640
133EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.72136078

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001873_stomach_inflammation6.07184978
2MP0001664_abnormal_digestion5.06852944
3MP0000470_abnormal_stomach_morphology3.89152188
4MP0003806_abnormal_nucleotide_metabolis3.28556740
5MP0010234_abnormal_vibrissa_follicle2.52820874
6MP0001663_abnormal_digestive_system2.24350446
7MP0010386_abnormal_urinary_bladder2.23306539
8MP0008004_abnormal_stomach_pH17.1270696
9MP0005381_digestive/alimentary_phenotyp1.96483015
10MP0001666_abnormal_nutrient_absorption1.89897887
11MP0003195_calcinosis1.89692550
12MP0005165_increased_susceptibility_to1.63802897
13MP0004264_abnormal_extraembryonic_tissu1.56732715
14MP0003950_abnormal_plasma_membrane1.47031748
15MP0000477_abnormal_intestine_morphology1.36894718
16MP0003943_abnormal_hepatobiliary_system1.36802370
17MP0006054_spinal_hemorrhage1.36144117
18MP0000537_abnormal_urethra_morphology1.31059376
19MP0009840_abnormal_foam_cell1.26974225
20MP0005083_abnormal_biliary_tract1.23261893
21MP0003705_abnormal_hypodermis_morpholog1.20959221
22MP0005023_abnormal_wound_healing1.19264446
23MP0005670_abnormal_white_adipose1.19087896
24MP0002138_abnormal_hepatobiliary_system1.17721165
25MP0008057_abnormal_DNA_replication1.15226733
26MP0001944_abnormal_pancreas_morphology1.14666354
27MP0000462_abnormal_digestive_system1.13658092
28MP0001756_abnormal_urination1.11416112
29MP0003283_abnormal_digestive_organ1.09556946
30MP0003300_gastrointestinal_ulcer1.09419303
31MP0000538_abnormal_urinary_bladder1.08980355
32MP0008438_abnormal_cutaneous_collagen1.04102476
33MP0004782_abnormal_surfactant_physiolog0.99803512
34MP0005085_abnormal_gallbladder_physiolo0.98932459
35MP0002909_abnormal_adrenal_gland0.97393276
36MP0003186_abnormal_redox_activity0.96552826
37MP0003938_abnormal_ear_development0.93934258
38MP0003045_fibrosis0.93207034
39MP0002249_abnormal_larynx_morphology0.92063402
40MP0000490_abnormal_crypts_of0.88830067
41MP0005220_abnormal_exocrine_pancreas0.86562671
42MP0009384_cardiac_valve_regurgitation0.84951895
43MP0004036_abnormal_muscle_relaxation0.83420491
44MP0002877_abnormal_melanocyte_morpholog0.80664854
45MP0002876_abnormal_thyroid_physiology0.80215776
46MP0004215_abnormal_myocardial_fiber0.78609039
47MP0002168_other_aberrant_phenotype0.76355606
48MP0001270_distended_abdomen0.74518356
49MP0002234_abnormal_pharynx_morphology0.74463778
50MP0010155_abnormal_intestine_physiology0.72202022
51MP0000003_abnormal_adipose_tissue0.71867833
52MP0005365_abnormal_bile_salt0.71732041
53MP0008875_abnormal_xenobiotic_pharmacok0.71622943
54MP0004185_abnormal_adipocyte_glucose0.70263593
55MP0010329_abnormal_lipoprotein_level0.69647203
56MP0005266_abnormal_metabolism0.69154373
57MP0002089_abnormal_postnatal_growth/wei0.68833789
58MP0002928_abnormal_bile_duct0.66282971
59MP0004484_altered_response_of0.64486868
60MP0002796_impaired_skin_barrier0.63348048
61MP0010352_gastrointestinal_tract_polyps0.63143562
62MP0005636_abnormal_mineral_homeostasis0.61755659
63MP0000467_abnormal_esophagus_morphology0.60611236
64MP0003315_abnormal_perineum_morphology0.59395790
65MP0005375_adipose_tissue_phenotype0.58701410
66MP0010678_abnormal_skin_adnexa0.55242217
67MP0003868_abnormal_feces_composition0.54945527
68MP0005058_abnormal_lysosome_morphology0.54531405
69MP0002837_dystrophic_cardiac_calcinosis0.53775100
70MP0003866_abnormal_defecation0.52331835
71MP0005197_abnormal_uvea_morphology0.51856955
72MP0004947_skin_inflammation0.51453376
73MP0002233_abnormal_nose_morphology0.49916483
74MP0003959_abnormal_lean_body0.49434566
75MP0008872_abnormal_physiological_respon0.49116956
76MP0002282_abnormal_trachea_morphology0.48465563
77MP0004134_abnormal_chest_morphology0.48107142
78MP0004858_abnormal_nervous_system0.47596876
79MP0002139_abnormal_hepatobiliary_system0.47202287
80MP0001849_ear_inflammation0.47163473
81MP0000163_abnormal_cartilage_morphology0.47078981
82MP0003566_abnormal_cell_adhesion0.46801729
83MP0003075_altered_response_to0.46285998
84MP0005360_urolithiasis0.45060335
85MP0001243_abnormal_dermal_layer0.43725436
86MP0001216_abnormal_epidermal_layer0.43019400
87MP0002009_preneoplasia0.42883010
88MP0003119_abnormal_digestive_system0.42445763
89MP0003453_abnormal_keratinocyte_physiol0.42238321
90MP0002118_abnormal_lipid_homeostasis0.39209526
91MP0005166_decreased_susceptibility_to0.38618252
92MP0003252_abnormal_bile_duct0.37736382
93MP0002060_abnormal_skin_morphology0.37405722
94MP0002693_abnormal_pancreas_physiology0.37110066
95MP0009780_abnormal_chondrocyte_physiolo0.36502159
96MP0002019_abnormal_tumor_incidence0.35575406
97MP0003953_abnormal_hormone_level0.34917678
98MP0008873_increased_physiological_sensi0.34267482
99MP0002078_abnormal_glucose_homeostasis0.33250719
100MP0005501_abnormal_skin_physiology0.32658643
101MP0005367_renal/urinary_system_phenotyp0.32471903
102MP0000516_abnormal_urinary_system0.32471903
103MP0009053_abnormal_anal_canal0.30763188
104MP0003191_abnormal_cellular_cholesterol0.30661268
105MP0001845_abnormal_inflammatory_respons0.30012617
106MP0000609_abnormal_liver_physiology0.29491471
107MP0005584_abnormal_enzyme/coenzyme_acti0.28268097
108MP0002254_reproductive_system_inflammat0.27271733
109MP0003638_abnormal_response/metabolism_0.27126016
110MP0005408_hypopigmentation0.26848401
111MP0004019_abnormal_vitamin_homeostasis0.25923460
112MP0005248_abnormal_Harderian_gland0.25657171
113MP0003329_amyloid_beta_deposits0.24757006
114MP0000367_abnormal_coat/_hair0.24093967
115MP0000598_abnormal_liver_morphology0.24035480
116MP0002970_abnormal_white_adipose0.23983291
117MP0005376_homeostasis/metabolism_phenot0.23912179
118MP0002098_abnormal_vibrissa_morphology0.23719848
119MP0004043_abnormal_pH_regulation0.23600390
120MP0005310_abnormal_salivary_gland0.22913970
121MP0009642_abnormal_blood_homeostasis0.22691947
122MP0005319_abnormal_enzyme/_coenzyme0.22525383
123MP0003724_increased_susceptibility_to0.22339741
124MP0010771_integument_phenotype0.21918524
125MP0000613_abnormal_salivary_gland0.21738883
126MP0005076_abnormal_cell_differentiation0.21132797
127MP0005275_abnormal_skin_tensile0.19008638
128MP0005332_abnormal_amino_acid0.18948583
129MP0005666_abnormal_adipose_tissue0.18783251
130MP0009643_abnormal_urine_homeostasis0.18313727
131MP0000566_synostosis0.17994888
132MP0004130_abnormal_muscle_cell0.17894319
133MP0001191_abnormal_skin_condition0.17828450
134MP0009931_abnormal_skin_appearance0.16860501
135MP0008961_abnormal_basal_metabolism0.16095387
136MP0004272_abnormal_basement_membrane0.15867066
137MP0000013_abnormal_adipose_tissue0.15601530
138MP0005464_abnormal_platelet_physiology0.14474576

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)9.84698290
2Abnormal number of erythroid precursors (HP:0012131)8.66581445
3Abnormality of cells of the erythroid lineage (HP:0012130)7.72781343
4Azoospermia (HP:0000027)5.55242542
5Palpitations (HP:0001962)4.50147044
6Megaloblastic anemia (HP:0001889)4.45383355
7Abnormality of the vitamin B12 metabolism (HP:0004341)4.31052063
8Woolly hair (HP:0002224)4.27479506
9Abnormality of aromatic amino acid family metabolism (HP:0004338)4.22090480
10Goiter (HP:0000853)4.21961984
11Abnormality of vitamin B metabolism (HP:0004340)4.06822797
12Abnormality of small intestinal villus morphology (HP:0011472)4.03405194
13Villous atrophy (HP:0011473)4.03405194
14Syncope (HP:0001279)3.93056781
15Abnormal spermatogenesis (HP:0008669)3.76395336
16Abnormality of vitamin metabolism (HP:0100508)3.71739125
17Gout (HP:0001997)3.67902692
18Short nail (HP:0001799)3.62503412
19Abnormality of methionine metabolism (HP:0010901)3.51057624
20Intrahepatic cholestasis (HP:0001406)3.45618652
21Abnormality of purine metabolism (HP:0004352)3.37821501
22Short 1st metacarpal (HP:0010034)3.35756170
23Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)3.35756170
24Sex reversal (HP:0012245)3.34437419
25Abnormal sex determination (HP:0012244)3.34437419
26Micronodular cirrhosis (HP:0001413)3.33560341
27Flat acetabular roof (HP:0003180)3.33357861
28Ventricular fibrillation (HP:0001663)3.26561847
29Steatorrhea (HP:0002570)3.24249567
30Glomerulosclerosis (HP:0000096)3.23239624
31Exocrine pancreatic insufficiency (HP:0001738)3.17128597
32Broad metatarsal (HP:0001783)3.16646462
33Abnormal hair laboratory examination (HP:0003328)3.15537167
34Fat malabsorption (HP:0002630)3.14934401
35Complement deficiency (HP:0004431)3.04732371
36Back pain (HP:0003418)2.97377673
37Frequent falls (HP:0002359)2.96395721
38Arterial tortuosity (HP:0005116)2.95632069
39Abnormality of the gastric mucosa (HP:0004295)2.93643917
40Abnormality of the lumbar spine (HP:0100712)2.87963067
41Focal segmental glomerulosclerosis (HP:0000097)2.79626794
42Ventricular arrhythmia (HP:0004308)2.78991423
43Atrophic scars (HP:0001075)2.76777317
44Hyperlipoproteinemia (HP:0010980)2.75580498
45Prolonged partial thromboplastin time (HP:0003645)2.75529529
46Milia (HP:0001056)2.72487161
47Abnormality of complement system (HP:0005339)2.71926585
48Cupped ribs (HP:0000887)2.62291131
49Vertebral arch anomaly (HP:0008438)2.61473230
50Curly hair (HP:0002212)2.58358137
51Vascular tortuosity (HP:0004948)2.57336151
52Renal cortical cysts (HP:0000803)2.56209775
53Ventricular tachycardia (HP:0004756)2.54912850
54Hyperuricemia (HP:0002149)2.54514871
55Increased purine levels (HP:0004368)2.54514871
56Abnormality of monocarboxylic acid metabolism (HP:0010996)2.53146106
57Hydroxyprolinuria (HP:0003080)2.52972544
58Abnormality of proline metabolism (HP:0010907)2.52972544
59Abnormality of glutamine family amino acid metabolism (HP:0010902)2.51583446
60Vascular calcification (HP:0004934)2.49765414
61Hemorrhage of the eye (HP:0011885)2.49241830
62Tubular atrophy (HP:0000092)2.46252705
63Hypoglycemic seizures (HP:0002173)2.41603576
64Abnormal cartilage morphology (HP:0002763)2.35054398
65Adrenal hypoplasia (HP:0000835)2.34744483
66Rectal prolapse (HP:0002035)2.33928960
67Conjugated hyperbilirubinemia (HP:0002908)2.33365888
68Abdominal distention (HP:0003270)2.32416025
69Agitation (HP:0000713)2.31877042
70Cardiovascular calcification (HP:0011915)2.31238698
71Urethral obstruction (HP:0000796)2.31141110
72Abnormality of aspartate family amino acid metabolism (HP:0010899)2.30844098
73Tubulointerstitial nephritis (HP:0001970)2.28536279
74Radial bowing (HP:0002986)2.27675136
75Onycholysis (HP:0001806)2.27290473
76Esophageal varix (HP:0002040)2.26552309
77Fragile nails (HP:0001808)2.25938016
78Ankyloglossia (HP:0010296)2.25043362
79Pili torti (HP:0003777)2.24962385
80Redundant skin (HP:0001582)2.23578617
81Aortic dissection (HP:0002647)2.22109967
82Beaking of vertebral bodies (HP:0004568)2.22022513
83Cone-rod dystrophy (HP:0000548)2.21434669
84Hypobetalipoproteinemia (HP:0003563)2.15650704
85Aortic regurgitation (HP:0001659)2.15285622
86Axonal loss (HP:0003447)2.14041239
87Hypolipoproteinemia (HP:0010981)2.13968495
88Pustule (HP:0200039)2.13936428
89Palmoplantar hyperkeratosis (HP:0000972)2.13752862
90Hemiplegia (HP:0002301)2.11665295
91Sensorimotor neuropathy (HP:0007141)2.10530446
92Increased mean platelet volume (HP:0011877)2.09446165
93Abnormal foot bone ossification (HP:0010675)2.09284603
94Conjunctival hamartoma (HP:0100780)2.08551069
95Short phalanx of the thumb (HP:0009660)2.08496243
96Fragile skin (HP:0001030)2.06418730
97Late onset (HP:0003584)2.06053883
98Plantar hyperkeratosis (HP:0007556)2.04211252
99Abnormal biliary tract morphology (HP:0012440)2.03803202
100Alopecia of scalp (HP:0002293)2.03698069
101Germ cell neoplasia (HP:0100728)2.01176684
102Abnormalities of placenta or umbilical cord (HP:0001194)2.00957880
103Intention tremor (HP:0002080)2.00912654
104Deep venous thrombosis (HP:0002625)2.00385808
105Overlapping toe (HP:0001845)1.99462874
106Sudden cardiac death (HP:0001645)1.99428282
107Infantile muscular hypotonia (HP:0008947)1.99199299
108Hypoglycemic coma (HP:0001325)1.97225496
109Abnormality of nucleobase metabolism (HP:0010932)1.93462935
110Pterygium (HP:0001059)1.93339290
111Palmar hyperkeratosis (HP:0010765)1.92544672
112Abnormality of iron homeostasis (HP:0011031)1.91329756
113Intestinal atresia (HP:0011100)1.90859384
114Malnutrition (HP:0004395)1.90810248
115Aplasia/Hypoplasia of the abdominal wall musculature (HP:0010318)1.88450677
116Abnormal tarsal ossification (HP:0008369)1.86990740
117Amyloidosis (HP:0011034)1.86014036
118Abnormality of the aortic arch (HP:0012303)1.85776030
119Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.84811973
120Growth hormone excess (HP:0000845)1.84805924
121Ketoacidosis (HP:0001993)1.83571245
122Glomerulonephritis (HP:0000099)1.83504092
123Hyperglycemia (HP:0003074)1.82394609
124Hypoalphalipoproteinemia (HP:0003233)1.82234252
125Hypotension (HP:0002615)1.81927174
126Vertebral hypoplasia (HP:0008417)1.81375795
127Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.81375795
128Prolonged neonatal jaundice (HP:0006579)1.80284341
129Hyperinsulinemic hypoglycemia (HP:0000825)1.80079927
130Hyperphosphatemia (HP:0002905)1.80022347
131Follicular hyperkeratosis (HP:0007502)1.79805712
132Insulin resistance (HP:0000855)1.78120921
133Abnormality of the renal cortex (HP:0011035)1.77749339
134Seborrheic dermatitis (HP:0001051)1.77170047
135Hyperammonemia (HP:0001987)1.75757193
136Subacute progressive viral hepatitis (HP:0006572)1.74295166
137Abnormality of oral frenula (HP:0000190)1.74255754
138Abnormality of the 1st metacarpal (HP:0010009)1.72358429
139Xanthomatosis (HP:0000991)1.71659537
140Periodontitis (HP:0000704)1.70029649
141Ileus (HP:0002595)1.68817931
142Abnormality of the distal phalanx of the thumb (HP:0009617)1.68800517
143Mildly elevated creatine phosphokinase (HP:0008180)1.66557543
144Restlessness (HP:0000711)1.65709005
145Microretrognathia (HP:0000308)1.64752341
146Spastic diplegia (HP:0001264)1.63288576
147Achilles tendon contracture (HP:0001771)1.62758969
148Abnormality of the Achilles tendon (HP:0005109)1.59673893
149Lethargy (HP:0001254)1.59374108
150Congenital, generalized hypertrichosis (HP:0004540)1.59038919
151Renal salt wasting (HP:0000127)1.57924141
152Increased variability in muscle fiber diameter (HP:0003557)1.57849707
153Spinal cord compression (HP:0002176)1.57469141
154Testicular neoplasm (HP:0010788)1.56893150
155Tubulointerstitial fibrosis (HP:0005576)1.56666748
156Abnormal pancreas size (HP:0012094)1.55417238
157Polygenic inheritance (HP:0010982)1.54505097
158Abnormality of sulfur amino acid metabolism (HP:0004339)1.54212285
159Ketosis (HP:0001946)1.53337177
160Breast carcinoma (HP:0003002)1.53203291
161Hypoplasia of dental enamel (HP:0006297)1.52785745
162Abnormality of carpal bone ossification (HP:0006257)1.52512100

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST45.05357100
2MST1R4.22026099
3IRAK32.56639251
4PKN22.07214285
5TRIB32.05857480
6NLK2.03709640
7ERBB412.5421740
8PBK1.91056992
9PASK1.81417220
10DYRK31.81098849
11MET1.79050538
12LRRK21.77225895
13LMTK21.68890619
14STK38L1.66446863
15IRAK21.65826912
16MAP3K121.64910399
17FGFR31.62371486
18MAP3K21.59455836
19SIK11.54078568
20KSR21.52874910
21FRK1.52169398
22MAP3K91.44686952
23FER1.43418405
24MAP2K21.38923032
25PTK61.38610337
26PRKG21.37538803
27STK101.37064794
28STK381.33374781
29NUAK11.27603456
30TRPM71.27016300
31STK161.22866041
32MAP2K11.22684063
33CDK81.19596825
34STK241.18198758
35RIPK41.17989348
36PIK3CG1.12622005
37BMPR1B1.06941414
38EPHA21.02607042
39RIPK11.01802010
40DAPK20.94150528
41PRKCI0.92354864
42TESK10.91013635
43ERN10.90506931
44STK390.89785376
45CASK0.86708153
46TAF10.86499807
47PAK40.86075537
48PAK30.85713131
49NME10.83164473
50FGFR40.81878588
51FYN0.78400125
52PDGFRB0.75367012
53NEK10.72406157
54FLT30.71258311
55MELK0.69943748
56NEK90.68127151
57FGFR20.67621510
58DDR20.67614863
59MAP3K80.66266943
60PTK20.66156552
61PDK40.66146749
62PDK30.66146749
63WNK40.65723371
64JAK10.65546611
65TAOK10.64756572
66MYLK0.64580980
67CSNK1G10.64551049
68ROCK20.64057199
69EPHA30.63833658
70EIF2AK30.62227273
71MKNK20.61167847
72MAP4K20.60743737
73BCKDK0.59246345
74EPHB20.58178355
75LATS10.57644397
76ICK0.57233918
77BMX0.56028759
78ERBB20.53831064
79EEF2K0.53091358
80EPHB10.52142751
81RPS6KB20.51808735
82PRKCE0.51370894
83MAP3K40.50463974
84MAP3K60.49265941
85TNIK0.48788322
86SRC0.48518802
87LIMK10.44572119
88MAP3K100.43803892
89DAPK10.42079978
90TRIM280.41414970
91IRAK10.41307844
92PDPK10.40895792
93ZAP700.40456997
94CDK90.40442291
95GRK60.39598213
96PDGFRA0.38515986
97ROCK10.38207274
98TTN0.36271657
99IGF1R0.35988064
100MAP3K30.35798518
101MAP3K70.35443113
102RET0.35396195
103ACVR1B0.33381177
104PDK20.33271802
105CSK0.31988091
106CAMK2B0.31171221
107RPS6KA20.30819194
108MATK0.30726835
109ALK0.29059278
110NME20.28514486
111KSR10.28418969
112MAP3K130.28207664
113MAP3K10.27836293
114DMPK0.27783392
115PDK10.27684158
116CAMK2D0.27459159
117CAMKK10.27297574
118SCYL20.27127792
119SIK30.27110544
120CDK60.27024541
121GRK10.26895567
122EGFR0.26682707
123FGR0.24383049
124BCR0.24328980
125NTRK10.23690793
126TGFBR10.23337616
127MAP2K60.22927269
128OXSR10.22713331
129PAK20.22645042
130MAPK110.21894950
131ADRBK10.21143548
132HIPK20.20181731
133ARAF0.20037599
134PRKD10.19537270
135CAMK2G0.19403384
136BMPR20.19350842
137PRKCQ0.17860155
138PRKAA20.17579005
139TYRO30.17571859
140PAK10.16951666
141DYRK1B0.15801357
142PIK3CA0.14329639
143MINK10.13367772
144STK30.13335070
145AKT20.13150940
146FGFR10.12012004
147ILK0.11216631
148PAK60.10792386
149RPS6KA10.10173152
150CDC42BPA0.10090473
151MAPKAPK20.09699124

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009805.05938563
2Sulfur metabolism_Homo sapiens_hsa009204.90701973
3Gastric acid secretion_Homo sapiens_hsa049714.58781336
4Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005124.54198531
5Drug metabolism - cytochrome P450_Homo sapiens_hsa009824.05151584
6Chemical carcinogenesis_Homo sapiens_hsa052043.55249140
7Collecting duct acid secretion_Homo sapiens_hsa049663.43089935
8Glutathione metabolism_Homo sapiens_hsa004803.42850941
9Steroid hormone biosynthesis_Homo sapiens_hsa001402.78737498
10Fat digestion and absorption_Homo sapiens_hsa049752.77275462
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.65078763
12Caffeine metabolism_Homo sapiens_hsa002322.34175155
13Vitamin B6 metabolism_Homo sapiens_hsa007502.24652008
14Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.13814102
15Complement and coagulation cascades_Homo sapiens_hsa046102.10390342
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.05597846
17Vitamin digestion and absorption_Homo sapiens_hsa049772.01495528
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.85458046
19Drug metabolism - other enzymes_Homo sapiens_hsa009831.82987025
20Mineral absorption_Homo sapiens_hsa049781.81489141
21Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.59274865
22Linoleic acid metabolism_Homo sapiens_hsa005911.58755485
23Nitrogen metabolism_Homo sapiens_hsa009101.46964959
24Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.34054992
25Ether lipid metabolism_Homo sapiens_hsa005651.32021194
26Pancreatic secretion_Homo sapiens_hsa049721.30899207
27Fatty acid degradation_Homo sapiens_hsa000711.26679892
28Other glycan degradation_Homo sapiens_hsa005111.21251942
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.18323573
30Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.14910278
31Thyroid hormone synthesis_Homo sapiens_hsa049181.10904424
32Protein digestion and absorption_Homo sapiens_hsa049741.09278968
33Retinol metabolism_Homo sapiens_hsa008301.07761429
34Pyruvate metabolism_Homo sapiens_hsa006200.97719939
35Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.94214269
36Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92971282
37Bile secretion_Homo sapiens_hsa049760.89252299
38Thyroid cancer_Homo sapiens_hsa052160.84259306
39Glycerolipid metabolism_Homo sapiens_hsa005610.83868694
40Histidine metabolism_Homo sapiens_hsa003400.81593637
41Propanoate metabolism_Homo sapiens_hsa006400.79597042
42Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.78402849
43Arginine and proline metabolism_Homo sapiens_hsa003300.76182911
44Sulfur relay system_Homo sapiens_hsa041220.75957972
45Carbon metabolism_Homo sapiens_hsa012000.75696876
46Maturity onset diabetes of the young_Homo sapiens_hsa049500.75317466
47Tight junction_Homo sapiens_hsa045300.75217208
48Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75036377
49Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74671663
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73438137
51Pentose and glucuronate interconversions_Homo sapiens_hsa000400.72423717
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.72275124
53Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67477321
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.67320055
55Folate biosynthesis_Homo sapiens_hsa007900.65909887
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64439495
57Circadian rhythm_Homo sapiens_hsa047100.63787624
58Glycosaminoglycan degradation_Homo sapiens_hsa005310.61172318
59Phenylalanine metabolism_Homo sapiens_hsa003600.61054660
60PPAR signaling pathway_Homo sapiens_hsa033200.60839926
61Butanoate metabolism_Homo sapiens_hsa006500.60726351
62Fatty acid metabolism_Homo sapiens_hsa012120.58267177
63N-Glycan biosynthesis_Homo sapiens_hsa005100.55359432
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.54449023
65Cyanoamino acid metabolism_Homo sapiens_hsa004600.53648750
66Arachidonic acid metabolism_Homo sapiens_hsa005900.49977097
67beta-Alanine metabolism_Homo sapiens_hsa004100.49968694
68Leukocyte transendothelial migration_Homo sapiens_hsa046700.49790377
69Metabolic pathways_Homo sapiens_hsa011000.49180818
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48861558
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.48362024
72Fructose and mannose metabolism_Homo sapiens_hsa000510.47955218
73Arginine biosynthesis_Homo sapiens_hsa002200.47330134
74Adherens junction_Homo sapiens_hsa045200.45984155
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.44802910
76Oxidative phosphorylation_Homo sapiens_hsa001900.43387817
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42448178
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.41147375
79Taste transduction_Homo sapiens_hsa047420.40954416
80Dorso-ventral axis formation_Homo sapiens_hsa043200.40757320
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40721581
82TGF-beta signaling pathway_Homo sapiens_hsa043500.40694597
83Pentose phosphate pathway_Homo sapiens_hsa000300.39719915
84Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.38615798
85Bladder cancer_Homo sapiens_hsa052190.36822147
86Inositol phosphate metabolism_Homo sapiens_hsa005620.34625117
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.30990074
88Proteoglycans in cancer_Homo sapiens_hsa052050.30544475
89Glucagon signaling pathway_Homo sapiens_hsa049220.30530301
90Starch and sucrose metabolism_Homo sapiens_hsa005000.30522949
91Salivary secretion_Homo sapiens_hsa049700.28668016
92Tryptophan metabolism_Homo sapiens_hsa003800.26910262
93Salmonella infection_Homo sapiens_hsa051320.24498062
94Lysosome_Homo sapiens_hsa041420.24081469
95Hepatitis C_Homo sapiens_hsa051600.24040802
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.22557551
97Galactose metabolism_Homo sapiens_hsa000520.21794781
98Insulin resistance_Homo sapiens_hsa049310.21019182
99Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.20641703
100One carbon pool by folate_Homo sapiens_hsa006700.20518053
101Protein export_Homo sapiens_hsa030600.19612865
102Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.18882735
103Shigellosis_Homo sapiens_hsa051310.18716815
104Biosynthesis of amino acids_Homo sapiens_hsa012300.18439001
105Synaptic vesicle cycle_Homo sapiens_hsa047210.18386127
106Focal adhesion_Homo sapiens_hsa045100.17184477
107Tyrosine metabolism_Homo sapiens_hsa003500.16600982
108Endometrial cancer_Homo sapiens_hsa052130.15928599
109Estrogen signaling pathway_Homo sapiens_hsa049150.15815400
110Vibrio cholerae infection_Homo sapiens_hsa051100.15053296
111VEGF signaling pathway_Homo sapiens_hsa043700.14248151
112Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.14046439
113GnRH signaling pathway_Homo sapiens_hsa049120.12810610
114ECM-receptor interaction_Homo sapiens_hsa045120.12677760
115ABC transporters_Homo sapiens_hsa020100.12654337
116Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.11231310
117cGMP-PKG signaling pathway_Homo sapiens_hsa040220.10501094
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.09985137
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.09650186
120Sphingolipid metabolism_Homo sapiens_hsa006000.09253900
121Platelet activation_Homo sapiens_hsa046110.09159879
122Cysteine and methionine metabolism_Homo sapiens_hsa002700.08361252
123Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.07721444
124Peroxisome_Homo sapiens_hsa041460.07637611
125Fatty acid biosynthesis_Homo sapiens_hsa000610.07276593
126Renin secretion_Homo sapiens_hsa049240.07248247
127Primary bile acid biosynthesis_Homo sapiens_hsa001200.07026488
128Insulin secretion_Homo sapiens_hsa049110.06499924

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