Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.35257655 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.16443821 |
3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.16443821 |
4 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.74599610 |
5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.69975610 |
6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.69975610 |
7 | modulation by symbiont of host immune response (GO:0052553) | 3.69975610 |
8 | positive regulation by symbiont of host defense response (GO:0052509) | 3.69975610 |
9 | modulation by symbiont of host defense response (GO:0052031) | 3.69975610 |
10 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.69975610 |
11 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.67262710 |
12 | response to peptidoglycan (GO:0032494) | 3.62910063 |
13 | detection of other organism (GO:0098543) | 3.61210110 |
14 | detection of bacterium (GO:0016045) | 3.57555709 |
15 | neutrophil activation involved in immune response (GO:0002283) | 3.53271124 |
16 | barbed-end actin filament capping (GO:0051016) | 3.36051426 |
17 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.24143949 |
18 | regulation of cholesterol homeostasis (GO:2000188) | 3.21134257 |
19 | leukocyte aggregation (GO:0070486) | 3.21066027 |
20 | macrophage activation involved in immune response (GO:0002281) | 3.20807299 |
21 | positive regulation of histone deacetylation (GO:0031065) | 3.12572238 |
22 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.11550069 |
23 | low-density lipoprotein particle clearance (GO:0034383) | 3.11248109 |
24 | pinocytosis (GO:0006907) | 3.01690457 |
25 | mannose metabolic process (GO:0006013) | 3.01251633 |
26 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.99183981 |
27 | detection of external biotic stimulus (GO:0098581) | 2.99061010 |
28 | pentose-phosphate shunt (GO:0006098) | 2.99019198 |
29 | germinal center formation (GO:0002467) | 2.97354495 |
30 | regulation of gamma-delta T cell activation (GO:0046643) | 2.96506848 |
31 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.92024330 |
32 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.90806867 |
33 | regulation of leukocyte degranulation (GO:0043300) | 2.87181401 |
34 | regulation of necroptotic process (GO:0060544) | 2.83718274 |
35 | regulation of mast cell degranulation (GO:0043304) | 2.83520961 |
36 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.82400377 |
37 | regulation of cholesterol storage (GO:0010885) | 2.81896155 |
38 | NIK/NF-kappaB signaling (GO:0038061) | 2.80043018 |
39 | response to type I interferon (GO:0034340) | 2.79174692 |
40 | type I interferon signaling pathway (GO:0060337) | 2.78092842 |
41 | cellular response to type I interferon (GO:0071357) | 2.78092842 |
42 | valine metabolic process (GO:0006573) | 2.77916320 |
43 | positive regulation of lamellipodium assembly (GO:0010592) | 2.74949938 |
44 | lysine metabolic process (GO:0006553) | 2.74497416 |
45 | lysine catabolic process (GO:0006554) | 2.74497416 |
46 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.73951579 |
47 | positive regulation of p38MAPK cascade (GO:1900745) | 2.72334364 |
48 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.71164333 |
49 | maternal placenta development (GO:0001893) | 2.70682182 |
50 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.68012254 |
51 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.66586734 |
52 | response to muramyl dipeptide (GO:0032495) | 2.66252834 |
53 | morphogenesis of an endothelium (GO:0003159) | 2.65266850 |
54 | endothelial tube morphogenesis (GO:0061154) | 2.65266850 |
55 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.64321312 |
56 | response to host (GO:0075136) | 2.64321312 |
57 | response to host defenses (GO:0052200) | 2.64321312 |
58 | regulation of necrotic cell death (GO:0010939) | 2.64261114 |
59 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.63065375 |
60 | defense response to fungus (GO:0050832) | 2.62153231 |
61 | response to laminar fluid shear stress (GO:0034616) | 2.61742777 |
62 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.61395068 |
63 | B cell receptor signaling pathway (GO:0050853) | 2.60916338 |
64 | embryonic process involved in female pregnancy (GO:0060136) | 2.60816805 |
65 | positive thymic T cell selection (GO:0045059) | 2.60139950 |
66 | regulation of tolerance induction (GO:0002643) | 2.59921586 |
67 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.59797257 |
68 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.59711195 |
69 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.59083759 |
70 | NADPH regeneration (GO:0006740) | 2.58851092 |
71 | apoptotic process involved in morphogenesis (GO:0060561) | 2.58802957 |
72 | trophectodermal cell differentiation (GO:0001829) | 2.58572382 |
73 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.58397937 |
74 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.57969538 |
75 | 2-oxoglutarate metabolic process (GO:0006103) | 2.57143515 |
76 | tolerance induction (GO:0002507) | 2.54843542 |
77 | carnitine shuttle (GO:0006853) | 2.54335059 |
78 | detection of molecule of bacterial origin (GO:0032490) | 2.53907881 |
79 | stress fiber assembly (GO:0043149) | 2.52946245 |
80 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.52306397 |
81 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.51115754 |
82 | response to host immune response (GO:0052572) | 2.51115754 |
83 | fatty acid transmembrane transport (GO:1902001) | 2.50782123 |
84 | regulation of T cell tolerance induction (GO:0002664) | 2.49850040 |
85 | respiratory burst (GO:0045730) | 2.49378722 |
86 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.49314406 |
87 | negative regulation of interleukin-12 production (GO:0032695) | 2.48690027 |
88 | detection of biotic stimulus (GO:0009595) | 2.48393658 |
89 | regulation of podosome assembly (GO:0071801) | 2.48235394 |
90 | neutrophil activation (GO:0042119) | 2.47397975 |
91 | granulocyte activation (GO:0036230) | 2.46661044 |
92 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.45278192 |
93 | regulation of integrin activation (GO:0033623) | 2.44472715 |
94 | cell-substrate junction assembly (GO:0007044) | 2.44267853 |
95 | sulfur amino acid catabolic process (GO:0000098) | 2.43923176 |
96 | myeloid dendritic cell differentiation (GO:0043011) | 2.43803283 |
97 | regulation of extracellular matrix disassembly (GO:0010715) | 2.43084633 |
98 | positive regulation of lamellipodium organization (GO:1902745) | 2.42187431 |
99 | apoptotic cell clearance (GO:0043277) | 2.41834803 |
100 | regulation of superoxide anion generation (GO:0032928) | 2.41743830 |
101 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.41555876 |
102 | establishment of endothelial barrier (GO:0061028) | 2.41532001 |
103 | protein localization to endosome (GO:0036010) | 2.41531808 |
104 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.41335581 |
105 | positive regulation of protein deacetylation (GO:0090312) | 2.40544371 |
106 | epithelial cell-cell adhesion (GO:0090136) | 2.39115175 |
107 | skeletal muscle adaptation (GO:0043501) | 2.38967524 |
108 | cellular hyperosmotic response (GO:0071474) | 2.37717212 |
109 | actin-myosin filament sliding (GO:0033275) | 2.36989894 |
110 | muscle filament sliding (GO:0030049) | 2.36989894 |
111 | growth hormone receptor signaling pathway (GO:0060396) | 2.36158727 |
112 | embryonic placenta development (GO:0001892) | 2.34993074 |
113 | positive regulation of extracellular matrix organization (GO:1903055) | 2.34937147 |
114 | regulation of p38MAPK cascade (GO:1900744) | 2.34442819 |
115 | leukocyte cell-cell adhesion (GO:0007159) | 2.34364736 |
116 | negative thymic T cell selection (GO:0045060) | 2.34284981 |
117 | positive regulation of receptor recycling (GO:0001921) | 2.33533341 |
118 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.33532639 |
119 | tricarboxylic acid metabolic process (GO:0072350) | 2.32640932 |
120 | glycosphingolipid catabolic process (GO:0046479) | 2.32599416 |
121 | positive regulation of lipid storage (GO:0010884) | 2.31668612 |
122 | negative regulation of necroptotic process (GO:0060546) | 2.31567573 |
123 | negative regulation of phagocytosis (GO:0050765) | 2.31523085 |
124 | myeloid cell activation involved in immune response (GO:0002275) | 2.30582542 |
125 | cellular extravasation (GO:0045123) | 2.30158280 |
126 | positive regulation of B cell differentiation (GO:0045579) | 2.29756077 |
127 | negative regulation of cell size (GO:0045792) | 2.29340372 |
128 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.28652500 |
129 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.27775353 |
130 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.27151948 |
131 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.26954047 |
132 | negative regulation of interleukin-6 production (GO:0032715) | 2.26877708 |
133 | 4-hydroxyproline metabolic process (GO:0019471) | 2.26551706 |
134 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.26300403 |
135 | positive regulation of tolerance induction (GO:0002645) | 2.26078047 |
136 | regulation of regulated secretory pathway (GO:1903305) | 2.25817521 |
137 | plasma membrane repair (GO:0001778) | 2.25776620 |
138 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.25297494 |
139 | modulation by symbiont of host cellular process (GO:0044068) | 2.24694262 |
140 | regulation of antigen processing and presentation (GO:0002577) | 2.24418962 |
141 | T cell selection (GO:0045058) | 2.24243262 |
142 | immunoglobulin mediated immune response (GO:0016064) | 2.23764237 |
143 | sarcomere organization (GO:0045214) | 2.22158810 |
144 | cellular response to osmotic stress (GO:0071470) | 2.21435568 |
145 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 2.21349954 |
146 | negative regulation of heart growth (GO:0061117) | 2.21349954 |
147 | phospholipid homeostasis (GO:0055091) | 2.20654563 |
148 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.20091442 |
149 | hepatocyte apoptotic process (GO:0097284) | 2.19609631 |
150 | striated muscle atrophy (GO:0014891) | 2.18419715 |
151 | response to fungus (GO:0009620) | 2.16782767 |
152 | fatty acid beta-oxidation (GO:0006635) | 2.14629146 |
153 | oxaloacetate metabolic process (GO:0006107) | 2.14406768 |
154 | hormone catabolic process (GO:0042447) | 2.13461279 |
155 | glucose catabolic process (GO:0006007) | 2.13083576 |
156 | hypotonic response (GO:0006971) | 2.11955809 |
157 | regulation of translational fidelity (GO:0006450) | 2.11842446 |
158 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.11827397 |
159 | hemidesmosome assembly (GO:0031581) | 2.11445089 |
160 | negative regulation of stress fiber assembly (GO:0051497) | 2.11064299 |
161 | nucleotide salvage (GO:0043173) | 2.09399359 |
162 | amino-acid betaine transport (GO:0015838) | 2.09076359 |
163 | carnitine transport (GO:0015879) | 2.09076359 |
164 | thymic T cell selection (GO:0045061) | 2.08556026 |
165 | negative regulation of innate immune response (GO:0045824) | 2.08437508 |
166 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.08360247 |
167 | focal adhesion assembly (GO:0048041) | 2.07609867 |
168 | cell-substrate adherens junction assembly (GO:0007045) | 2.07609867 |
169 | ethanol oxidation (GO:0006069) | 2.04972603 |
170 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.04666468 |
171 | regulation of response to interferon-gamma (GO:0060330) | 2.03986085 |
172 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.03299730 |
173 | purine nucleotide salvage (GO:0032261) | 2.02925104 |
174 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.02728153 |
175 | negative regulation of cell killing (GO:0031342) | 2.02728153 |
176 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.02253944 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.85089883 |
2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.80503051 |
3 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.79586142 |
4 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.73272299 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 2.60609818 |
6 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.36637298 |
7 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.35257980 |
8 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.26616811 |
9 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.19359287 |
10 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.12673440 |
11 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.07288561 |
12 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.03358002 |
13 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.99069590 |
14 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.97362038 |
15 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.93870037 |
16 | * MAF_26560356_Chip-Seq_TH1_Human | 1.88086957 |
17 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.83891522 |
18 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.82273898 |
19 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.79510236 |
20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.78422606 |
21 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.74999322 |
22 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.73920392 |
23 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.71184797 |
24 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.68103971 |
25 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.67682111 |
26 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.66895418 |
27 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.66812712 |
28 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.66486465 |
29 | UTX_26944678_Chip-Seq_JUKART_Human | 1.65650018 |
30 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.65335245 |
31 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.64623645 |
32 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.63825753 |
33 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.61961918 |
34 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.57779458 |
35 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.57042168 |
36 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.56954817 |
37 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55215700 |
38 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.54651017 |
39 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54556115 |
40 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.54249737 |
41 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.54157642 |
42 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.53635439 |
43 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.53308258 |
44 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.52124091 |
45 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.51769443 |
46 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.49792481 |
47 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.44590556 |
48 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.43866059 |
49 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.41208470 |
50 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.39210906 |
51 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.37965369 |
52 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.36544683 |
53 | * MYB_26560356_Chip-Seq_TH2_Human | 1.35200771 |
54 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.34606529 |
55 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.34320623 |
56 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33889323 |
57 | * MYB_26560356_Chip-Seq_TH1_Human | 1.32354441 |
58 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.31645048 |
59 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.31637292 |
60 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.31031735 |
61 | SPI1_23127762_ChIP-Seq_K562_Human | 1.31020575 |
62 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.29886727 |
63 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.29666151 |
64 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.28377668 |
65 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.28143847 |
66 | * GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.27389368 |
67 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.27281097 |
68 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.25501125 |
69 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.25003657 |
70 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.24700652 |
71 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.23271478 |
72 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.22008543 |
73 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.21346524 |
74 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.20458604 |
75 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.18206234 |
76 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.17806416 |
77 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.16650965 |
78 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.16275126 |
79 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.16213809 |
80 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.16203495 |
81 | * MAF_26560356_Chip-Seq_TH2_Human | 1.15882517 |
82 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15459648 |
83 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.15440434 |
84 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 1.14527046 |
85 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.14395565 |
86 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.14173751 |
87 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.13859200 |
88 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.13383973 |
89 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.12639899 |
90 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.12171963 |
91 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.11552240 |
92 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10939777 |
93 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.10916029 |
94 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.09994016 |
95 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.09649350 |
96 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.09496368 |
97 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.09472054 |
98 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.08964611 |
99 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.08935944 |
100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.08935944 |
101 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.08935944 |
102 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.08277803 |
103 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.08069322 |
104 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.06966587 |
105 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.05898805 |
106 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.05756409 |
107 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.05437133 |
108 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.04549201 |
109 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.03810897 |
110 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.03810897 |
111 | * SMC4_20622854_ChIP-Seq_HELA_Human | 1.02700083 |
112 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.02539913 |
113 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.01732184 |
114 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.01489056 |
115 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01243495 |
116 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.00538937 |
117 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.00525439 |
118 | GATA1_19941826_ChIP-Seq_K562_Human | 1.00420855 |
119 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.99565746 |
120 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99173408 |
121 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.98863512 |
122 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.96787927 |
123 | * ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.96736476 |
124 | * P68_20966046_ChIP-Seq_HELA_Human | 0.96080705 |
125 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.95846855 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 2.76121711 |
2 | MP0005360_urolithiasis | 2.52453767 |
3 | MP0005451_abnormal_body_composition | 2.45495063 |
4 | MP0003303_peritoneal_inflammation | 2.31406868 |
5 | MP0003300_gastrointestinal_ulcer | 2.26585123 |
6 | MP0009278_abnormal_bone_marrow | 2.24112243 |
7 | MP0010352_gastrointestinal_tract_polyps | 2.21371321 |
8 | MP0003436_decreased_susceptibility_to | 2.17593526 |
9 | MP0003191_abnormal_cellular_cholesterol | 2.14702999 |
10 | MP0009840_abnormal_foam_cell | 2.04487628 |
11 | MP0003566_abnormal_cell_adhesion | 2.02140973 |
12 | MP0002148_abnormal_hypersensitivity_rea | 1.85789339 |
13 | MP0003172_abnormal_lysosome_physiology | 1.79988368 |
14 | MP0002837_dystrophic_cardiac_calcinosis | 1.74783896 |
15 | MP0000685_abnormal_immune_system | 1.71083539 |
16 | MP0003806_abnormal_nucleotide_metabolis | 1.69481028 |
17 | MP0008260_abnormal_autophagy | 1.67891440 |
18 | MP0010234_abnormal_vibrissa_follicle | 1.66923748 |
19 | MP0002139_abnormal_hepatobiliary_system | 1.65222599 |
20 | MP0008438_abnormal_cutaneous_collagen | 1.62567166 |
21 | MP0004947_skin_inflammation | 1.61590771 |
22 | MP0010155_abnormal_intestine_physiology | 1.61081967 |
23 | MP0005076_abnormal_cell_differentiation | 1.54885652 |
24 | MP0002998_abnormal_bone_remodeling | 1.50251096 |
25 | MP0001958_emphysema | 1.47914807 |
26 | MP0009785_altered_susceptibility_to | 1.47304066 |
27 | MP0000343_altered_response_to | 1.46850681 |
28 | MP0005023_abnormal_wound_healing | 1.46594890 |
29 | MP0001835_abnormal_antigen_presentation | 1.44787324 |
30 | MP0004510_myositis | 1.44523585 |
31 | MP0003279_aneurysm | 1.44123204 |
32 | MP0001873_stomach_inflammation | 1.43343772 |
33 | MP0003091_abnormal_cell_migration | 1.42237573 |
34 | MP0005387_immune_system_phenotype | 1.40791967 |
35 | MP0001790_abnormal_immune_system | 1.40791967 |
36 | MP0005464_abnormal_platelet_physiology | 1.38945634 |
37 | MP0005025_abnormal_response_to | 1.38214035 |
38 | MP0005085_abnormal_gallbladder_physiolo | 1.37897910 |
39 | MP0001800_abnormal_humoral_immune | 1.37504082 |
40 | MP0004185_abnormal_adipocyte_glucose | 1.36637039 |
41 | MP0004264_abnormal_extraembryonic_tissu | 1.36120182 |
42 | MP0005397_hematopoietic_system_phenotyp | 1.35808032 |
43 | MP0001545_abnormal_hematopoietic_system | 1.35808032 |
44 | MP0005058_abnormal_lysosome_morphology | 1.35056255 |
45 | MP0002138_abnormal_hepatobiliary_system | 1.34964225 |
46 | MP0002405_respiratory_system_inflammati | 1.31557316 |
47 | MP0005365_abnormal_bile_salt | 1.31052184 |
48 | MP0002419_abnormal_innate_immunity | 1.26056321 |
49 | MP0003453_abnormal_keratinocyte_physiol | 1.25075121 |
50 | MP0005166_decreased_susceptibility_to | 1.24343509 |
51 | MP0003724_increased_susceptibility_to | 1.23703463 |
52 | MP0003828_pulmonary_edema | 1.23675897 |
53 | MP0004130_abnormal_muscle_cell | 1.22859968 |
54 | MP0002132_abnormal_respiratory_system | 1.22729732 |
55 | MP0005167_abnormal_blood-brain_barrier | 1.22600114 |
56 | MP0002452_abnormal_antigen_presenting | 1.22291340 |
57 | MP0001853_heart_inflammation | 1.21647985 |
58 | MP0003183_abnormal_peptide_metabolism | 1.20841492 |
59 | MP0000465_gastrointestinal_hemorrhage | 1.20778063 |
60 | MP0005000_abnormal_immune_tolerance | 1.18741860 |
61 | MP0000609_abnormal_liver_physiology | 1.18502416 |
62 | MP0001845_abnormal_inflammatory_respons | 1.18386014 |
63 | MP0008875_abnormal_xenobiotic_pharmacok | 1.18277425 |
64 | MP0004087_abnormal_muscle_fiber | 1.16040970 |
65 | MP0006082_CNS_inflammation | 1.15002751 |
66 | MP0000750_abnormal_muscle_regeneration | 1.13780877 |
67 | MP0008961_abnormal_basal_metabolism | 1.13755146 |
68 | MP0005319_abnormal_enzyme/_coenzyme | 1.13039143 |
69 | MP0000749_muscle_degeneration | 1.12765299 |
70 | MP0010329_abnormal_lipoprotein_level | 1.12603268 |
71 | MP0002420_abnormal_adaptive_immunity | 1.12497223 |
72 | MP0001819_abnormal_immune_cell | 1.12495184 |
73 | MP0000604_amyloidosis | 1.12262974 |
74 | MP0002723_abnormal_immune_serum | 1.11354567 |
75 | MP0001533_abnormal_skeleton_physiology | 1.10664962 |
76 | MP0000490_abnormal_crypts_of | 1.10318595 |
77 | MP0003252_abnormal_bile_duct | 1.10249812 |
78 | MP0005666_abnormal_adipose_tissue | 1.09916700 |
79 | MP0002166_altered_tumor_susceptibility | 1.08792445 |
80 | MP0002877_abnormal_melanocyte_morpholog | 1.08611287 |
81 | MP0000858_altered_metastatic_potential | 1.07735207 |
82 | MP0005164_abnormal_response_to | 1.07502513 |
83 | MP0004084_abnormal_cardiac_muscle | 1.07459069 |
84 | MP0000751_myopathy | 1.06923955 |
85 | MP0001851_eye_inflammation | 1.06508833 |
86 | MP0005165_increased_susceptibility_to | 1.06022447 |
87 | MP0009643_abnormal_urine_homeostasis | 1.05803276 |
88 | MP0010630_abnormal_cardiac_muscle | 1.03532606 |
89 | MP0002398_abnormal_bone_marrow | 1.03412247 |
90 | MP0003646_muscle_fatigue | 1.03110853 |
91 | MP0001849_ear_inflammation | 1.02932540 |
92 | MP0003448_altered_tumor_morphology | 1.01907125 |
93 | MP0002269_muscular_atrophy | 1.01792398 |
94 | MP0001666_abnormal_nutrient_absorption | 1.01762099 |
95 | MP0008004_abnormal_stomach_pH | 1.01040484 |
96 | MP0005310_abnormal_salivary_gland | 1.00963119 |
97 | MP0003866_abnormal_defecation | 1.00540974 |
98 | MP0003763_abnormal_thymus_physiology | 1.00397767 |
99 | MP0000689_abnormal_spleen_morphology | 0.98315873 |
100 | MP0003045_fibrosis | 0.97998203 |
101 | MP0008469_abnormal_protein_level | 0.97824774 |
102 | MP0002722_abnormal_immune_system | 0.97735948 |
103 | MP0005390_skeleton_phenotype | 0.97283257 |
104 | MP0006054_spinal_hemorrhage | 0.97188788 |
105 | MP0009333_abnormal_splenocyte_physiolog | 0.96912583 |
106 | MP0004808_abnormal_hematopoietic_stem | 0.96538971 |
107 | MP0000716_abnormal_immune_system | 0.96067210 |
108 | MP0005671_abnormal_response_to | 0.95466228 |
109 | MP0004883_abnormal_blood_vessel | 0.95262068 |
110 | MP0002396_abnormal_hematopoietic_system | 0.94980875 |
111 | MP0000733_abnormal_muscle_development | 0.92946138 |
112 | MP0003075_altered_response_to | 0.91962291 |
113 | MP0000747_muscle_weakness | 0.91248531 |
114 | MP0000249_abnormal_blood_vessel | 0.91070090 |
115 | MP0002796_impaired_skin_barrier | 0.90804959 |
116 | MP0005375_adipose_tissue_phenotype | 0.90552714 |
117 | MP0005330_cardiomyopathy | 0.89763693 |
118 | MP0010307_abnormal_tumor_latency | 0.88770510 |
119 | MP0002429_abnormal_blood_cell | 0.88329999 |
120 | MP0005083_abnormal_biliary_tract | 0.88212113 |
121 | MP0002933_joint_inflammation | 0.87814786 |
122 | MP0002106_abnormal_muscle_physiology | 0.85369289 |
123 | MP0002136_abnormal_kidney_physiology | 0.85156621 |
124 | MP0003795_abnormal_bone_structure | 0.83661213 |
125 | MP0004858_abnormal_nervous_system | 0.83173251 |
126 | MP0009764_decreased_sensitivity_to | 0.82145759 |
127 | MP0003329_amyloid_beta_deposits | 0.81957237 |
128 | MP0001663_abnormal_digestive_system | 0.79849069 |
129 | MP0000703_abnormal_thymus_morphology | 0.78895463 |
130 | MP0005670_abnormal_white_adipose | 0.77516606 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Right ventricular cardiomyopathy (HP:0011663) | 3.39679851 |
2 | Ulnar deviation of the wrist (HP:0003049) | 3.36895753 |
3 | Increased connective tissue (HP:0009025) | 3.35885966 |
4 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.34699952 |
5 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.34699952 |
6 | Abnormality of glycolipid metabolism (HP:0010969) | 3.34699952 |
7 | Eczematoid dermatitis (HP:0000976) | 3.31286442 |
8 | Exercise-induced muscle cramps (HP:0003710) | 3.05006571 |
9 | Hyporeflexia of lower limbs (HP:0002600) | 2.86422602 |
10 | Asymmetric septal hypertrophy (HP:0001670) | 2.79053337 |
11 | Type 1 muscle fiber predominance (HP:0003803) | 2.78671256 |
12 | Muscle fiber inclusion bodies (HP:0100299) | 2.77719492 |
13 | Exercise-induced myalgia (HP:0003738) | 2.77453549 |
14 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.72524536 |
15 | Interstitial pulmonary disease (HP:0006530) | 2.69530202 |
16 | Pustule (HP:0200039) | 2.67108920 |
17 | Ventricular tachycardia (HP:0004756) | 2.65399868 |
18 | Myoglobinuria (HP:0002913) | 2.64251105 |
19 | Muscle fiber splitting (HP:0003555) | 2.63296074 |
20 | Abnormality of the nasal mucosa (HP:0000433) | 2.56174481 |
21 | Chronic obstructive pulmonary disease (HP:0006510) | 2.55974084 |
22 | Obstructive lung disease (HP:0006536) | 2.55974084 |
23 | Autoimmune thrombocytopenia (HP:0001973) | 2.52330083 |
24 | Increased cerebral lipofuscin (HP:0011813) | 2.52172082 |
25 | Systemic lupus erythematosus (HP:0002725) | 2.51026648 |
26 | Mediastinal lymphadenopathy (HP:0100721) | 2.49799141 |
27 | Vertebral compression fractures (HP:0002953) | 2.48725899 |
28 | Recurrent abscess formation (HP:0002722) | 2.48105611 |
29 | Distal arthrogryposis (HP:0005684) | 2.45785012 |
30 | Myopathic facies (HP:0002058) | 2.44163182 |
31 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.42526900 |
32 | Difficulty climbing stairs (HP:0003551) | 2.39776168 |
33 | Difficulty running (HP:0009046) | 2.39742278 |
34 | Polycythemia (HP:0001901) | 2.36721661 |
35 | Distal lower limb amyotrophy (HP:0008944) | 2.36562814 |
36 | Protrusio acetabuli (HP:0003179) | 2.36433832 |
37 | Spontaneous hematomas (HP:0007420) | 2.34667586 |
38 | Rhabdomyolysis (HP:0003201) | 2.33923910 |
39 | Nemaline bodies (HP:0003798) | 2.32425328 |
40 | Frequent falls (HP:0002359) | 2.31691048 |
41 | Meningitis (HP:0001287) | 2.29575978 |
42 | Loss of speech (HP:0002371) | 2.29181922 |
43 | Purpura (HP:0000979) | 2.28956261 |
44 | Gastrointestinal stroma tumor (HP:0100723) | 2.28737083 |
45 | Petechiae (HP:0000967) | 2.28475671 |
46 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.28101259 |
47 | Recurrent skin infections (HP:0001581) | 2.27697489 |
48 | Round ear (HP:0100830) | 2.26987421 |
49 | Nasal polyposis (HP:0100582) | 2.24638065 |
50 | Gastrointestinal infarctions (HP:0005244) | 2.21130592 |
51 | Flat acetabular roof (HP:0003180) | 2.19165596 |
52 | Prolonged bleeding time (HP:0003010) | 2.16658377 |
53 | Amyloidosis (HP:0011034) | 2.16250245 |
54 | Esophageal varix (HP:0002040) | 2.16231790 |
55 | Cerebral aneurysm (HP:0004944) | 2.14550562 |
56 | Recurrent fungal infections (HP:0002841) | 2.14262531 |
57 | Abnormal platelet volume (HP:0011876) | 2.11966226 |
58 | Axonal loss (HP:0003447) | 2.11360549 |
59 | Ulnar bowing (HP:0003031) | 2.11240550 |
60 | Emphysema (HP:0002097) | 2.10235557 |
61 | Impaired platelet aggregation (HP:0003540) | 2.09043086 |
62 | Abnormal platelet function (HP:0011869) | 2.09043086 |
63 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.08766992 |
64 | Myocardial infarction (HP:0001658) | 2.08467012 |
65 | Vasculitis (HP:0002633) | 2.08318038 |
66 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.07891854 |
67 | Recurrent bacterial skin infections (HP:0005406) | 2.07861753 |
68 | Premature rupture of membranes (HP:0001788) | 2.05564372 |
69 | Myositis (HP:0100614) | 2.05444381 |
70 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.03002617 |
71 | Hemorrhage of the eye (HP:0011885) | 2.02768377 |
72 | IgM deficiency (HP:0002850) | 2.02423841 |
73 | Aortic aneurysm (HP:0004942) | 2.01102137 |
74 | Optic neuritis (HP:0100653) | 2.00567215 |
75 | Retrobulbar optic neuritis (HP:0100654) | 2.00567215 |
76 | Increased mean platelet volume (HP:0011877) | 2.00530339 |
77 | Dilatation of the ascending aorta (HP:0005111) | 2.00382892 |
78 | Epistaxis (HP:0000421) | 1.99955806 |
79 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.99869077 |
80 | Abnormality of macrophages (HP:0004311) | 1.99785252 |
81 | Metaphyseal cupping (HP:0003021) | 1.99551597 |
82 | Distal lower limb muscle weakness (HP:0009053) | 1.99039900 |
83 | Spondylolisthesis (HP:0003302) | 1.97397429 |
84 | Deep venous thrombosis (HP:0002625) | 1.96958826 |
85 | Mucopolysacchariduria (HP:0008155) | 1.96647033 |
86 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.96647033 |
87 | Hyperactive renin-angiotensin system (HP:0000841) | 1.96459059 |
88 | Gout (HP:0001997) | 1.96263414 |
89 | Hematochezia (HP:0002573) | 1.95064868 |
90 | EMG: myopathic abnormalities (HP:0003458) | 1.94460371 |
91 | Stomatitis (HP:0010280) | 1.94175090 |
92 | Increased IgE level (HP:0003212) | 1.93777875 |
93 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.93428432 |
94 | Osteolytic defects of the hand bones (HP:0009699) | 1.93428432 |
95 | Osteomyelitis (HP:0002754) | 1.92613981 |
96 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.91290833 |
97 | Hypertriglyceridemia (HP:0002155) | 1.90286932 |
98 | Colitis (HP:0002583) | 1.89779491 |
99 | Hepatosplenomegaly (HP:0001433) | 1.89432936 |
100 | Recurrent cutaneous fungal infections (HP:0011370) | 1.87771356 |
101 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.87771356 |
102 | Peritonitis (HP:0002586) | 1.87523347 |
103 | Increased serum ferritin (HP:0003281) | 1.87214491 |
104 | Polygenic inheritance (HP:0010982) | 1.85686325 |
105 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.85511020 |
106 | Cellulitis (HP:0100658) | 1.84985465 |
107 | Pulmonary infiltrates (HP:0002113) | 1.84759894 |
108 | Increased density of long bones (HP:0006392) | 1.84588316 |
109 | Abnormality of purine metabolism (HP:0004352) | 1.84377855 |
110 | Xanthomatosis (HP:0000991) | 1.82974950 |
111 | Urticaria (HP:0001025) | 1.82866498 |
112 | Gastrointestinal inflammation (HP:0004386) | 1.82806724 |
113 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.81839873 |
114 | Chest pain (HP:0100749) | 1.81690602 |
115 | Inflammation of the large intestine (HP:0002037) | 1.81264219 |
116 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.80171188 |
117 | Restrictive lung disease (HP:0002091) | 1.79880707 |
118 | Hypertensive crisis (HP:0100735) | 1.78929399 |
119 | Gingival bleeding (HP:0000225) | 1.78876756 |
120 | Sudden death (HP:0001699) | 1.78653508 |
121 | Cervical subluxation (HP:0003308) | 1.78540078 |
122 | Facial diplegia (HP:0001349) | 1.77912846 |
123 | Abnormality of iron homeostasis (HP:0011031) | 1.75516300 |
124 | Thin bony cortex (HP:0002753) | 1.75366284 |
125 | Premature loss of primary teeth (HP:0006323) | 1.74982209 |
126 | Abnormality of proline metabolism (HP:0010907) | 1.74675571 |
127 | Hydroxyprolinuria (HP:0003080) | 1.74675571 |
128 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.74256185 |
129 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.74256185 |
130 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.74256185 |
131 | Distal upper limb amyotrophy (HP:0007149) | 1.74035065 |
132 | Upper limb amyotrophy (HP:0009129) | 1.74035065 |
133 | Vacuolated lymphocytes (HP:0001922) | 1.71792912 |
134 | Hyperammonemia (HP:0001987) | 1.70615586 |
135 | Recurrent viral infections (HP:0004429) | 1.69614036 |
136 | Malnutrition (HP:0004395) | 1.69172923 |
137 | Gingivitis (HP:0000230) | 1.68590439 |
138 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.68185499 |
139 | Hypergammaglobulinemia (HP:0010702) | 1.67930249 |
140 | Dysostosis multiplex (HP:0000943) | 1.67868183 |
141 | Orchitis (HP:0100796) | 1.66291847 |
142 | Bone pain (HP:0002653) | 1.65107000 |
143 | Increased variability in muscle fiber diameter (HP:0003557) | 1.64684295 |
144 | Muscle stiffness (HP:0003552) | 1.64337983 |
145 | Rectal prolapse (HP:0002035) | 1.63697965 |
146 | Abnormality of the calcaneus (HP:0008364) | 1.61967189 |
147 | Hand muscle atrophy (HP:0009130) | 1.61533972 |
148 | Hyperglycinuria (HP:0003108) | 1.61404798 |
149 | Alopecia of scalp (HP:0002293) | 1.60833622 |
150 | Abnormal cartilage morphology (HP:0002763) | 1.60580265 |
151 | Limb-girdle muscle atrophy (HP:0003797) | 1.59823598 |
152 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.59394624 |
153 | Multiple enchondromatosis (HP:0005701) | 1.59355042 |
154 | Aneurysm (HP:0002617) | 1.58866580 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.91723061 |
2 | ERN1 | 3.44701070 |
3 | RIPK4 | 3.12180872 |
4 | PKN2 | 3.08518909 |
5 | PRPF4B | 3.03677480 |
6 | TTN | 2.98050700 |
7 | MAP4K1 | 2.69198217 |
8 | MAP3K10 | 2.42066870 |
9 | EEF2K | 2.41844441 |
10 | STK10 | 2.20398148 |
11 | EPHB1 | 2.16361792 |
12 | CDK12 | 2.14097632 |
13 | MAP2K3 | 2.09424809 |
14 | GRK6 | 1.90120011 |
15 | LRRK2 | 1.84872213 |
16 | SMG1 | 1.84019954 |
17 | PTK6 | 1.75149674 |
18 | RIPK1 | 1.73875212 |
19 | FGFR4 | 1.66299396 |
20 | MAP3K13 | 1.66123368 |
21 | CSK | 1.63786981 |
22 | TGFBR2 | 1.48022934 |
23 | CDC42BPA | 1.47414552 |
24 | ZAP70 | 1.46700735 |
25 | TBK1 | 1.45150790 |
26 | TYK2 | 1.44095470 |
27 | PAK4 | 1.43910704 |
28 | MAPKAPK3 | 1.42296135 |
29 | MAP3K3 | 1.41299476 |
30 | TAOK2 | 1.40308681 |
31 | MAP3K11 | 1.26843315 |
32 | BMX | 1.25937125 |
33 | FLT3 | 1.20597098 |
34 | PRKG2 | 1.19530279 |
35 | FES | 1.11579817 |
36 | JAK3 | 1.11120082 |
37 | DMPK | 1.09708553 |
38 | BCKDK | 1.07906131 |
39 | BTK | 1.05712625 |
40 | ICK | 1.05586234 |
41 | NME2 | 1.03912788 |
42 | EPHA2 | 1.03043405 |
43 | MAP3K7 | 1.02890109 |
44 | PDPK1 | 1.02389065 |
45 | KDR | 1.01981034 |
46 | SIK1 | 1.01836640 |
47 | MST4 | 1.01437611 |
48 | TRPM7 | 1.01246959 |
49 | RPS6KB2 | 1.01024695 |
50 | MATK | 1.00861564 |
51 | MARK2 | 0.98981139 |
52 | BLK | 0.97888551 |
53 | TAOK1 | 0.95447214 |
54 | TNK2 | 0.93875005 |
55 | MAP3K6 | 0.93574800 |
56 | NEK1 | 0.88630306 |
57 | PIM1 | 0.88489432 |
58 | PTK2 | 0.87529925 |
59 | CDK6 | 0.87296572 |
60 | MAPK11 | 0.86802294 |
61 | PDGFRA | 0.85672448 |
62 | ITK | 0.85617084 |
63 | JAK1 | 0.84074922 |
64 | ALK | 0.82383921 |
65 | HCK | 0.82077242 |
66 | MAP3K8 | 0.81913822 |
67 | MAPK12 | 0.80179306 |
68 | KIT | 0.78910329 |
69 | FGFR3 | 0.78053029 |
70 | PDK1 | 0.78026362 |
71 | MST1R | 0.76643579 |
72 | SIK3 | 0.75546041 |
73 | PIK3CG | 0.75139964 |
74 | MAP3K2 | 0.74794497 |
75 | LMTK2 | 0.74375891 |
76 | JAK2 | 0.73918290 |
77 | RPS6KA4 | 0.72435797 |
78 | MAP2K2 | 0.70614607 |
79 | KSR2 | 0.70232000 |
80 | OBSCN | 0.69982759 |
81 | CSF1R | 0.69195859 |
82 | HIPK2 | 0.67533461 |
83 | ARAF | 0.66631827 |
84 | CDK4 | 0.66412875 |
85 | MTOR | 0.63922260 |
86 | IKBKE | 0.62042742 |
87 | STK38 | 0.61949779 |
88 | STK24 | 0.61779851 |
89 | IRAK2 | 0.60802066 |
90 | LYN | 0.60702952 |
91 | TAOK3 | 0.58042635 |
92 | IRAK3 | 0.56626200 |
93 | MAP3K14 | 0.56276199 |
94 | MAPK7 | 0.55686059 |
95 | FGR | 0.55565081 |
96 | DDR2 | 0.55146700 |
97 | RPS6KA2 | 0.54633444 |
98 | IRAK1 | 0.54074099 |
99 | TESK2 | 0.53335648 |
100 | MAP2K6 | 0.50907302 |
101 | MAP3K1 | 0.50372805 |
102 | NEK2 | 0.50321516 |
103 | PIM2 | 0.49973630 |
104 | IKBKB | 0.49295330 |
105 | PTK2B | 0.48790646 |
106 | MOS | 0.48631844 |
107 | PRKAA2 | 0.48076798 |
108 | SYK | 0.47728554 |
109 | MARK3 | 0.47536882 |
110 | LCK | 0.47265828 |
111 | NEK9 | 0.46936658 |
112 | PRKD2 | 0.46705369 |
113 | MYLK | 0.45049232 |
114 | MAPKAPK2 | 0.44843680 |
115 | RET | 0.44524405 |
116 | RPS6KA6 | 0.44048462 |
117 | CHUK | 0.43985877 |
118 | TESK1 | 0.43891532 |
119 | TIE1 | 0.42990788 |
120 | RPS6KL1 | 0.42707054 |
121 | RPS6KC1 | 0.42707054 |
122 | PDGFRB | 0.42371282 |
123 | ILK | 0.41410387 |
124 | PDK3 | 0.40967773 |
125 | PDK4 | 0.40967773 |
126 | RPS6KA1 | 0.40217882 |
127 | GSK3A | 0.40179335 |
128 | BMPR2 | 0.39899579 |
129 | IRAK4 | 0.39206853 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.34798807 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.24843214 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.95639981 |
4 | Leishmaniasis_Homo sapiens_hsa05140 | 1.80342638 |
5 | Allograft rejection_Homo sapiens_hsa05330 | 1.79370369 |
6 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.77689676 |
7 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.77641209 |
8 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.73708395 |
9 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.69078914 |
10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.68365721 |
11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.63704865 |
12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.62779650 |
13 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.59223876 |
14 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.55064854 |
15 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.54071392 |
16 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.44556264 |
17 | Malaria_Homo sapiens_hsa05144 | 1.43193065 |
18 | Carbon metabolism_Homo sapiens_hsa01200 | 1.42037695 |
19 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.38311497 |
20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.32723646 |
21 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.31600221 |
22 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.30799294 |
23 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.27818368 |
24 | Insulin resistance_Homo sapiens_hsa04931 | 1.26412454 |
25 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.21727610 |
26 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.21327688 |
27 | Viral myocarditis_Homo sapiens_hsa05416 | 1.20432801 |
28 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.19765343 |
29 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.18515902 |
30 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.18388871 |
31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18370938 |
32 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.15897547 |
33 | Phagosome_Homo sapiens_hsa04145 | 1.15612254 |
34 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.14711693 |
35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.14694985 |
36 | Galactose metabolism_Homo sapiens_hsa00052 | 1.13488149 |
37 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.11944171 |
38 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.11265896 |
39 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.11137822 |
40 | Legionellosis_Homo sapiens_hsa05134 | 1.11118003 |
41 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.10486227 |
42 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.09907929 |
43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.08805531 |
44 | Shigellosis_Homo sapiens_hsa05131 | 1.08438686 |
45 | Lysine degradation_Homo sapiens_hsa00310 | 1.06527159 |
46 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.06491470 |
47 | Asthma_Homo sapiens_hsa05310 | 1.05714366 |
48 | Adherens junction_Homo sapiens_hsa04520 | 1.03282519 |
49 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.02381934 |
50 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.01419191 |
51 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.00936197 |
52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00654197 |
53 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.99771679 |
54 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.98824963 |
55 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.94297844 |
56 | Apoptosis_Homo sapiens_hsa04210 | 0.92416142 |
57 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.92218031 |
58 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.91997799 |
59 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.91579352 |
60 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.91206265 |
61 | Bladder cancer_Homo sapiens_hsa05219 | 0.89959831 |
62 | Bile secretion_Homo sapiens_hsa04976 | 0.89500871 |
63 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.88429301 |
64 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.87332539 |
65 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.86889801 |
66 | Focal adhesion_Homo sapiens_hsa04510 | 0.86351002 |
67 | Endocytosis_Homo sapiens_hsa04144 | 0.86092974 |
68 | Other glycan degradation_Homo sapiens_hsa00511 | 0.85451570 |
69 | Amoebiasis_Homo sapiens_hsa05146 | 0.85036215 |
70 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.84298575 |
71 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.84151592 |
72 | Tuberculosis_Homo sapiens_hsa05152 | 0.83681364 |
73 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.83407216 |
74 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.83205947 |
75 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.83033810 |
76 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.82168353 |
77 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.82103349 |
78 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.81222982 |
79 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.80883915 |
80 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.80872002 |
81 | Measles_Homo sapiens_hsa05162 | 0.80733055 |
82 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.79755795 |
83 | Pertussis_Homo sapiens_hsa05133 | 0.79443939 |
84 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.79386853 |
85 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.78234688 |
86 | Platelet activation_Homo sapiens_hsa04611 | 0.76472986 |
87 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.75687420 |
88 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.75184383 |
89 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.74782249 |
90 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.73961404 |
91 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.73632918 |
92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.72179188 |
93 | Salmonella infection_Homo sapiens_hsa05132 | 0.71400991 |
94 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.70201301 |
95 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.69528922 |
96 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.69493575 |
97 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69486053 |
98 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.69403156 |
99 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.69184570 |
100 | Influenza A_Homo sapiens_hsa05164 | 0.68281777 |
101 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.67941658 |
102 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67918898 |
103 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.67655759 |
104 | Histidine metabolism_Homo sapiens_hsa00340 | 0.67571592 |
105 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.67043805 |
106 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.66983511 |
107 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.66772698 |
108 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.66468495 |
109 | Sulfur relay system_Homo sapiens_hsa04122 | 0.66271600 |
110 | Lysosome_Homo sapiens_hsa04142 | 0.65654156 |
111 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.65100893 |
112 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.64333353 |
113 | Prion diseases_Homo sapiens_hsa05020 | 0.64315324 |
114 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.63565329 |
115 | Thyroid cancer_Homo sapiens_hsa05216 | 0.62172343 |
116 | HTLV-I infection_Homo sapiens_hsa05166 | 0.61699956 |
117 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.61126188 |
118 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.60696725 |
119 | Endometrial cancer_Homo sapiens_hsa05213 | 0.59507956 |
120 | ABC transporters_Homo sapiens_hsa02010 | 0.59153735 |
121 | Hepatitis B_Homo sapiens_hsa05161 | 0.59010713 |
122 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.58476331 |
123 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.57155848 |
124 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.57142545 |
125 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.56635535 |
126 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.56025235 |
127 | Hepatitis C_Homo sapiens_hsa05160 | 0.55609150 |
128 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.55065839 |
129 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.51292432 |
130 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50846509 |
131 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.49585098 |
132 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.48224745 |
133 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.44858827 |
134 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.44620350 |
135 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40547825 |