

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 9.46041978 |
| 2 | cytidine metabolic process (GO:0046087) | 9.46041978 |
| 3 | cytidine catabolic process (GO:0006216) | 9.46041978 |
| 4 | DNA deamination (GO:0045006) | 9.16762459 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 8.55321641 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 8.28302905 |
| 7 | membrane raft organization (GO:0031579) | 5.87570347 |
| 8 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 5.40339000 |
| 9 | eosinophil chemotaxis (GO:0048245) | 4.93515504 |
| 10 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.68360759 |
| 11 | eosinophil migration (GO:0072677) | 4.44184794 |
| 12 | positive regulation of monocyte chemotaxis (GO:0090026) | 4.41618761 |
| 13 | regulation of activation of Janus kinase activity (GO:0010533) | 4.38525144 |
| 14 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.38456597 |
| 15 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.28480535 |
| 16 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.23451563 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.21144334 |
| 18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 4.16847192 |
| 19 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.15769656 |
| 20 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.15769656 |
| 21 | proteasome assembly (GO:0043248) | 4.14861695 |
| 22 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.10191555 |
| 23 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.10191555 |
| 24 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.10191555 |
| 25 | negative regulation of viral genome replication (GO:0045071) | 4.04756856 |
| 26 | sequestering of actin monomers (GO:0042989) | 4.02864136 |
| 27 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.01825979 |
| 28 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.94229683 |
| 29 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.90861856 |
| 30 | actin nucleation (GO:0045010) | 3.90514258 |
| 31 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.89124339 |
| 32 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.87152288 |
| 33 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.87152288 |
| 34 | negative regulation of ligase activity (GO:0051352) | 3.82937387 |
| 35 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.82937387 |
| 36 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.80756068 |
| 37 | macrophage chemotaxis (GO:0048246) | 3.74951649 |
| 38 | regulation of interleukin-8 secretion (GO:2000482) | 3.72035978 |
| 39 | negative regulation of monooxygenase activity (GO:0032769) | 3.69035012 |
| 40 | negative regulation by host of viral transcription (GO:0043922) | 3.68360355 |
| 41 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.65833077 |
| 42 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.65714751 |
| 43 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.65573156 |
| 44 | regulation of sarcomere organization (GO:0060297) | 3.63494169 |
| 45 | negative regulation of T cell apoptotic process (GO:0070233) | 3.60932198 |
| 46 | T cell migration (GO:0072678) | 3.60618339 |
| 47 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.53669279 |
| 48 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.43849972 |
| 49 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 3.43629736 |
| 50 | cytolysis (GO:0019835) | 3.42825798 |
| 51 | ATP synthesis coupled proton transport (GO:0015986) | 3.41103079 |
| 52 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.41103079 |
| 53 | positive regulation of cell cycle arrest (GO:0071158) | 3.40344525 |
| 54 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.39062090 |
| 55 | platelet dense granule organization (GO:0060155) | 3.33136939 |
| 56 | regulation of cellular amine metabolic process (GO:0033238) | 3.31486243 |
| 57 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.29488064 |
| 58 | negative regulation of oxidoreductase activity (GO:0051354) | 3.26004404 |
| 59 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.24013221 |
| 60 | protein neddylation (GO:0045116) | 3.21570935 |
| 61 | response to interferon-beta (GO:0035456) | 3.18122836 |
| 62 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.15670510 |
| 63 | respiratory electron transport chain (GO:0022904) | 3.15560882 |
| 64 | regulation of skeletal muscle contraction (GO:0014819) | 3.14000571 |
| 65 | positive regulation of T cell chemotaxis (GO:0010820) | 3.12992640 |
| 66 | regulation of T cell chemotaxis (GO:0010819) | 3.12992640 |
| 67 | regulation of mononuclear cell migration (GO:0071675) | 3.08476610 |
| 68 | positive regulation of lymphocyte migration (GO:2000403) | 3.08474816 |
| 69 | electron transport chain (GO:0022900) | 3.08023724 |
| 70 | positive regulation of ligase activity (GO:0051351) | 3.06236123 |
| 71 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.05687241 |
| 72 | negative regulation of muscle hypertrophy (GO:0014741) | 3.03632452 |
| 73 | regulation of T cell tolerance induction (GO:0002664) | 3.01594757 |
| 74 | regulation of regulatory T cell differentiation (GO:0045589) | 3.00606955 |
| 75 | regulation of viral genome replication (GO:0045069) | 3.00063346 |
| 76 | DNA demethylation (GO:0080111) | 2.98525458 |
| 77 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.95056471 |
| 78 | termination of RNA polymerase III transcription (GO:0006386) | 2.95056471 |
| 79 | chaperone-mediated protein transport (GO:0072321) | 2.92107877 |
| 80 | lymphocyte chemotaxis (GO:0048247) | 2.90483583 |
| 81 | regulation of chronic inflammatory response (GO:0002676) | 2.87221491 |
| 82 | negative regulation of protein localization to cell surface (GO:2000009) | 2.86934658 |
| 83 | ribonucleoprotein complex disassembly (GO:0032988) | 2.86924482 |
| 84 | regulation of monocyte chemotaxis (GO:0090025) | 2.85658457 |
| 85 | positive regulation of defense response to virus by host (GO:0002230) | 2.81596182 |
| 86 | T cell costimulation (GO:0031295) | 2.80265181 |
| 87 | negative regulation of B cell proliferation (GO:0030889) | 2.79665260 |
| 88 | signal peptide processing (GO:0006465) | 2.78210177 |
| 89 | positive regulation of lamellipodium assembly (GO:0010592) | 2.77129529 |
| 90 | lymphocyte costimulation (GO:0031294) | 2.76608284 |
| 91 | positive thymic T cell selection (GO:0045059) | 2.72677800 |
| 92 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.71886439 |
| 93 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.71886439 |
| 94 | membrane budding (GO:0006900) | 2.71816981 |
| 95 | positive regulation of translational initiation (GO:0045948) | 2.71338889 |
| 96 | positive regulation of tolerance induction (GO:0002645) | 2.71184834 |
| 97 | regulation of calcium-mediated signaling (GO:0050848) | 2.70064520 |
| 98 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.69847242 |
| 99 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.69350483 |
| 100 | regulation of cell cycle arrest (GO:0071156) | 2.68949206 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.52342721 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.83467813 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.67479153 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.65913449 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.59636453 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.17481366 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.11069764 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.79884323 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.74302504 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.69357712 |
| 11 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.64805184 |
| 12 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.54778624 |
| 13 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.46496402 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.41640449 |
| 15 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.39900565 |
| 16 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.35669571 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.28483646 |
| 18 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.21787181 |
| 19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.11008288 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.04294125 |
| 21 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.99281375 |
| 22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.96558589 |
| 23 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.93988033 |
| 24 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.91700688 |
| 25 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.89608082 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.88949220 |
| 27 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.85371135 |
| 28 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.80480679 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.73104400 |
| 30 | MYB_26560356_Chip-Seq_TH2_Human | 1.55157963 |
| 31 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50069124 |
| 32 | GATA3_26560356_Chip-Seq_TH2_Human | 1.50015434 |
| 33 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.49990513 |
| 34 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.44750612 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44498341 |
| 36 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.39431011 |
| 37 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.38769914 |
| 38 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.37277426 |
| 39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.36669915 |
| 40 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.35112122 |
| 41 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.34883725 |
| 42 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.34035575 |
| 43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.29648425 |
| 44 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.29367910 |
| 45 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29294237 |
| 46 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29014820 |
| 47 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29014820 |
| 48 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.28753869 |
| 49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.25435372 |
| 50 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.25353352 |
| 51 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.24427844 |
| 52 | * AR_20517297_ChIP-Seq_VCAP_Human | 1.24424574 |
| 53 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.21262175 |
| 54 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.21040007 |
| 55 | CJUN_26792858_Chip-Seq_BT549_Human | 1.19165386 |
| 56 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.19084485 |
| 57 | P300_19829295_ChIP-Seq_ESCs_Human | 1.16806405 |
| 58 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15167366 |
| 59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.13642425 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.13367898 |
| 61 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11726759 |
| 62 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.11100056 |
| 63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.11022571 |
| 64 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10332864 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10332864 |
| 66 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.09581960 |
| 67 | EWS_26573619_Chip-Seq_HEK293_Human | 1.09329475 |
| 68 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.09082532 |
| 69 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.08768006 |
| 70 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.08158766 |
| 71 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07162838 |
| 72 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.06359291 |
| 73 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.05670167 |
| 74 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.03381847 |
| 75 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.02551600 |
| 76 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.01478413 |
| 77 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.01088023 |
| 78 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.98799194 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97025226 |
| 80 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.96495633 |
| 81 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.96291179 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.96028438 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 0.95047045 |
| 84 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.94136772 |
| 85 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93852079 |
| 86 | * JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.93090028 |
| 87 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.93089302 |
| 88 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92512901 |
| 89 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.92365271 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.91554490 |
| 91 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90890721 |
| 92 | * GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90383082 |
| 93 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89680522 |
| 94 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.89197236 |
| 95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.88186629 |
| 96 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.87629089 |
| 97 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.86115133 |
| 98 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.85617621 |
| 99 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.85336738 |
| 100 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.83814857 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003950_abnormal_plasma_membrane | 6.77989010 |
| 2 | MP0005671_abnormal_response_to | 5.19976764 |
| 3 | MP0009785_altered_susceptibility_to | 3.88923825 |
| 4 | MP0006082_CNS_inflammation | 3.07354961 |
| 5 | MP0000749_muscle_degeneration | 2.95831422 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.90640685 |
| 7 | MP0002102_abnormal_ear_morphology | 2.87589619 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.55246186 |
| 9 | MP0009333_abnormal_splenocyte_physiolog | 2.44061550 |
| 10 | MP0006054_spinal_hemorrhage | 2.39547896 |
| 11 | MP0002166_altered_tumor_susceptibility | 2.31138505 |
| 12 | MP0001853_heart_inflammation | 2.14172870 |
| 13 | MP0001873_stomach_inflammation | 2.13540675 |
| 14 | MP0001542_abnormal_bone_strength | 2.09673171 |
| 15 | MP0003763_abnormal_thymus_physiology | 2.01211421 |
| 16 | MP0002006_tumorigenesis | 2.01074235 |
| 17 | MP0005000_abnormal_immune_tolerance | 1.99481123 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.99052670 |
| 19 | MP0003448_altered_tumor_morphology | 1.89652156 |
| 20 | MP0002933_joint_inflammation | 1.87285213 |
| 21 | MP0000372_irregular_coat_pigmentation | 1.79342120 |
| 22 | MP0003786_premature_aging | 1.74000365 |
| 23 | MP0005025_abnormal_response_to | 1.72260818 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.69978500 |
| 25 | MP0001800_abnormal_humoral_immune | 1.68753305 |
| 26 | MP0002723_abnormal_immune_serum | 1.68444648 |
| 27 | MP0002420_abnormal_adaptive_immunity | 1.64186765 |
| 28 | MP0001819_abnormal_immune_cell | 1.59302650 |
| 29 | MP0004883_abnormal_blood_vessel | 1.56149337 |
| 30 | MP0000685_abnormal_immune_system | 1.54797010 |
| 31 | MP0003045_fibrosis | 1.51206590 |
| 32 | MP0001790_abnormal_immune_system | 1.50558488 |
| 33 | MP0005387_immune_system_phenotype | 1.50558488 |
| 34 | MP0002452_abnormal_antigen_presenting | 1.47037912 |
| 35 | MP0004084_abnormal_cardiac_muscle | 1.46660632 |
| 36 | MP0002405_respiratory_system_inflammati | 1.45225303 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 1.44941637 |
| 38 | MP0003866_abnormal_defecation | 1.41820971 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.35231369 |
| 40 | MP0003011_delayed_dark_adaptation | 1.32955361 |
| 41 | MP0002163_abnormal_gland_morphology | 1.32079982 |
| 42 | MP0005084_abnormal_gallbladder_morpholo | 1.28690466 |
| 43 | MP0008438_abnormal_cutaneous_collagen | 1.15484630 |
| 44 | MP0010155_abnormal_intestine_physiology | 1.14845940 |
| 45 | MP0002837_dystrophic_cardiac_calcinosis | 1.14682801 |
| 46 | MP0008469_abnormal_protein_level | 1.14657592 |
| 47 | MP0005330_cardiomyopathy | 1.13797413 |
| 48 | MP0010386_abnormal_urinary_bladder | 1.12176975 |
| 49 | MP0000716_abnormal_immune_system | 1.11849790 |
| 50 | MP0009763_increased_sensitivity_to | 1.10601419 |
| 51 | MP0005166_decreased_susceptibility_to | 1.09613412 |
| 52 | MP0006072_abnormal_retinal_apoptosis | 1.05169263 |
| 53 | MP0001905_abnormal_dopamine_level | 1.04639338 |
| 54 | MP0005360_urolithiasis | 1.04007894 |
| 55 | MP0001919_abnormal_reproductive_system | 1.03279794 |
| 56 | MP0001485_abnormal_pinna_reflex | 1.03028039 |
| 57 | MP0003252_abnormal_bile_duct | 1.02007432 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.01361931 |
| 59 | MP0002419_abnormal_innate_immunity | 1.00061845 |
| 60 | MP0008872_abnormal_physiological_respon | 0.98920580 |
| 61 | MP0002138_abnormal_hepatobiliary_system | 0.98014560 |
| 62 | MP0000858_altered_metastatic_potential | 0.97823398 |
| 63 | MP0002398_abnormal_bone_marrow | 0.96249471 |
| 64 | MP0000751_myopathy | 0.92707342 |
| 65 | MP0003195_calcinosis | 0.90683901 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 0.89838542 |
| 67 | MP0005253_abnormal_eye_physiology | 0.89738318 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.88032885 |
| 69 | MP0002972_abnormal_cardiac_muscle | 0.86422182 |
| 70 | MP0003137_abnormal_impulse_conducting | 0.85634637 |
| 71 | MP0005389_reproductive_system_phenotype | 0.84828019 |
| 72 | MP0009764_decreased_sensitivity_to | 0.84472342 |
| 73 | MP0005164_abnormal_response_to | 0.84208354 |
| 74 | MP0003279_aneurysm | 0.81699721 |
| 75 | MP0005275_abnormal_skin_tensile | 0.79830567 |
| 76 | MP0003186_abnormal_redox_activity | 0.79533513 |
| 77 | MP0002722_abnormal_immune_system | 0.78018953 |
| 78 | MP0004134_abnormal_chest_morphology | 0.77464178 |
| 79 | MP0003828_pulmonary_edema | 0.76658291 |
| 80 | MP0000689_abnormal_spleen_morphology | 0.76629746 |
| 81 | MP0002429_abnormal_blood_cell | 0.76191790 |
| 82 | MP0002095_abnormal_skin_pigmentation | 0.74975194 |
| 83 | MP0002282_abnormal_trachea_morphology | 0.72763683 |
| 84 | MP0005503_abnormal_tendon_morphology | 0.72644224 |
| 85 | MP0008789_abnormal_olfactory_epithelium | 0.70725429 |
| 86 | MP0003191_abnormal_cellular_cholesterol | 0.70247546 |
| 87 | MP0000639_abnormal_adrenal_gland | 0.69401191 |
| 88 | MP0005023_abnormal_wound_healing | 0.68612627 |
| 89 | MP0005319_abnormal_enzyme/_coenzyme | 0.68309834 |
| 90 | MP0004272_abnormal_basement_membrane | 0.67246443 |
| 91 | MP0006036_abnormal_mitochondrial_physio | 0.67190999 |
| 92 | MP0000569_abnormal_digit_pigmentation | 0.67151196 |
| 93 | MP0004036_abnormal_muscle_relaxation | 0.66695004 |
| 94 | MP0001661_extended_life_span | 0.65552375 |
| 95 | MP0001243_abnormal_dermal_layer | 0.63130185 |
| 96 | MP0009643_abnormal_urine_homeostasis | 0.62650557 |
| 97 | MP0000703_abnormal_thymus_morphology | 0.62599337 |
| 98 | MP0001764_abnormal_homeostasis | 0.62456349 |
| 99 | MP0005379_endocrine/exocrine_gland_phen | 0.62322091 |
| 100 | MP0000647_abnormal_sebaceous_gland | 0.61812232 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 6.43249074 |
| 2 | Hypoproteinemia (HP:0003075) | 4.30037218 |
| 3 | Type 2 muscle fiber atrophy (HP:0003554) | 4.26153535 |
| 4 | Amniotic constriction ring (HP:0009775) | 4.18859078 |
| 5 | Abnormality of placental membranes (HP:0011409) | 4.18859078 |
| 6 | T lymphocytopenia (HP:0005403) | 4.17907383 |
| 7 | Abnormality of T cell number (HP:0011839) | 4.06351432 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.88794870 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.85719918 |
| 10 | Calf muscle hypertrophy (HP:0008981) | 3.68316787 |
| 11 | Muscle fiber atrophy (HP:0100295) | 3.66191253 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.45282989 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.44255415 |
| 14 | Exercise-induced muscle cramps (HP:0003710) | 3.43970147 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.32566328 |
| 16 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.28530166 |
| 17 | Increased CSF lactate (HP:0002490) | 3.27410296 |
| 18 | IgG deficiency (HP:0004315) | 3.20781306 |
| 19 | Acute encephalopathy (HP:0006846) | 3.10472847 |
| 20 | Oral leukoplakia (HP:0002745) | 3.07090253 |
| 21 | Autoimmune hemolytic anemia (HP:0001890) | 3.06758787 |
| 22 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.91394889 |
| 23 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.91394889 |
| 24 | Hepatic necrosis (HP:0002605) | 2.88723932 |
| 25 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.83382748 |
| 26 | Cerebral edema (HP:0002181) | 2.80377667 |
| 27 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.75199778 |
| 28 | Hypoalbuminemia (HP:0003073) | 2.74668641 |
| 29 | Abnormal albumin level (HP:0012116) | 2.74668641 |
| 30 | Increased IgM level (HP:0003496) | 2.73446730 |
| 31 | Abnormality of T cells (HP:0002843) | 2.73035794 |
| 32 | Hypoplasia of the thymus (HP:0000778) | 2.71243166 |
| 33 | Popliteal pterygium (HP:0009756) | 2.69917241 |
| 34 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.61145906 |
| 35 | Renal Fanconi syndrome (HP:0001994) | 2.57244947 |
| 36 | Chronic diarrhea (HP:0002028) | 2.57108959 |
| 37 | Increased hepatocellular lipid droplets (HP:0006565) | 2.53577448 |
| 38 | Abnormality of the prostate (HP:0008775) | 2.49917954 |
| 39 | Myotonia (HP:0002486) | 2.49317658 |
| 40 | Exercise-induced myalgia (HP:0003738) | 2.45187686 |
| 41 | Renal cortical cysts (HP:0000803) | 2.43742558 |
| 42 | Pancreatic cysts (HP:0001737) | 2.41216398 |
| 43 | Increased intramyocellular lipid droplets (HP:0012240) | 2.30192398 |
| 44 | Lipid accumulation in hepatocytes (HP:0006561) | 2.26847530 |
| 45 | Spondylolisthesis (HP:0003302) | 2.26667825 |
| 46 | Weak cry (HP:0001612) | 2.26230094 |
| 47 | Sudden death (HP:0001699) | 2.24377668 |
| 48 | Abnormality of the neuromuscular junction (HP:0003398) | 2.22332393 |
| 49 | Fatigable weakness (HP:0003473) | 2.22332393 |
| 50 | Pustule (HP:0200039) | 2.22034413 |
| 51 | Type I transferrin isoform profile (HP:0003642) | 2.20871134 |
| 52 | Neck muscle weakness (HP:0000467) | 2.20421789 |
| 53 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.19158449 |
| 54 | Eosinophilia (HP:0001880) | 2.17805536 |
| 55 | Palpitations (HP:0001962) | 2.17738673 |
| 56 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.15873073 |
| 57 | Vascular tortuosity (HP:0004948) | 2.15790210 |
| 58 | Aortic dissection (HP:0002647) | 2.14409908 |
| 59 | 3-Methylglutaconic aciduria (HP:0003535) | 2.13012443 |
| 60 | Arterial tortuosity (HP:0005116) | 2.12645871 |
| 61 | Pancytopenia (HP:0001876) | 2.12101154 |
| 62 | Severe combined immunodeficiency (HP:0004430) | 2.10712071 |
| 63 | Respiratory failure (HP:0002878) | 2.09299516 |
| 64 | Gowers sign (HP:0003391) | 2.08598405 |
| 65 | True hermaphroditism (HP:0010459) | 2.08186560 |
| 66 | Posterior subcapsular cataract (HP:0007787) | 2.05508038 |
| 67 | Amyotrophic lateral sclerosis (HP:0007354) | 2.04711583 |
| 68 | Abnormality of eosinophils (HP:0001879) | 2.03784823 |
| 69 | Increased serum lactate (HP:0002151) | 2.03349320 |
| 70 | Abnormality of midbrain morphology (HP:0002418) | 2.02739456 |
| 71 | Molar tooth sign on MRI (HP:0002419) | 2.02739456 |
| 72 | Abolished electroretinogram (ERG) (HP:0000550) | 2.02275591 |
| 73 | Constricted visual fields (HP:0001133) | 2.02061899 |
| 74 | Recurrent cutaneous fungal infections (HP:0011370) | 1.99902320 |
| 75 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.99902320 |
| 76 | Lactic acidosis (HP:0003128) | 1.98878330 |
| 77 | Pulmonary fibrosis (HP:0002206) | 1.96947937 |
| 78 | Keratoconus (HP:0000563) | 1.96900095 |
| 79 | Increased corneal curvature (HP:0100692) | 1.96900095 |
| 80 | Hepatosplenomegaly (HP:0001433) | 1.96109441 |
| 81 | Stomatitis (HP:0010280) | 1.92623307 |
| 82 | Thyroiditis (HP:0100646) | 1.92124863 |
| 83 | Exercise intolerance (HP:0003546) | 1.90293088 |
| 84 | Parakeratosis (HP:0001036) | 1.88316991 |
| 85 | Recurrent bronchitis (HP:0002837) | 1.87278780 |
| 86 | Nemaline bodies (HP:0003798) | 1.87063494 |
| 87 | Pancreatic fibrosis (HP:0100732) | 1.86689084 |
| 88 | Muscle stiffness (HP:0003552) | 1.85674126 |
| 89 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.83059109 |
| 90 | Optic disc pallor (HP:0000543) | 1.81007916 |
| 91 | Exertional dyspnea (HP:0002875) | 1.80937188 |
| 92 | Abnormality of macrophages (HP:0004311) | 1.80457160 |
| 93 | Sparse eyelashes (HP:0000653) | 1.78640273 |
| 94 | Abnormality of the anterior horn cell (HP:0006802) | 1.78143666 |
| 95 | Degeneration of anterior horn cells (HP:0002398) | 1.78143666 |
| 96 | CNS demyelination (HP:0007305) | 1.77918511 |
| 97 | Increased muscle lipid content (HP:0009058) | 1.77887482 |
| 98 | Generalized aminoaciduria (HP:0002909) | 1.77778002 |
| 99 | Aplasia of the musculature (HP:0100854) | 1.76454983 |
| 100 | Pulmonary infiltrates (HP:0002113) | 1.76223498 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 4.32020314 |
| 2 | MAP3K12 | 4.16452464 |
| 3 | TXK | 3.73749743 |
| 4 | VRK2 | 3.12936266 |
| 5 | BCKDK | 2.88939519 |
| 6 | TESK2 | 2.87567437 |
| 7 | MUSK | 2.83517340 |
| 8 | MST4 | 2.72020037 |
| 9 | EIF2AK3 | 2.51276706 |
| 10 | LIMK1 | 2.39193277 |
| 11 | MYLK | 2.25351743 |
| 12 | CDK8 | 2.22499066 |
| 13 | TESK1 | 2.11107516 |
| 14 | BUB1 | 2.08760380 |
| 15 | NUAK1 | 1.81801049 |
| 16 | TRIM28 | 1.78625300 |
| 17 | STK16 | 1.77705599 |
| 18 | MAPKAPK5 | 1.68810313 |
| 19 | VRK1 | 1.59928362 |
| 20 | PIK3CG | 1.57139099 |
| 21 | TIE1 | 1.51863925 |
| 22 | ITK | 1.38895351 |
| 23 | GRK7 | 1.32568346 |
| 24 | ADRBK2 | 1.31692748 |
| 25 | SCYL2 | 1.27953302 |
| 26 | BMPR2 | 1.27367793 |
| 27 | GRK1 | 1.23526662 |
| 28 | DAPK1 | 1.23237621 |
| 29 | BCR | 1.17638427 |
| 30 | PIK3CA | 1.12479372 |
| 31 | BMPR1B | 1.07510946 |
| 32 | MAP4K2 | 1.06949324 |
| 33 | ERBB3 | 1.05790521 |
| 34 | EIF2AK1 | 1.04088352 |
| 35 | PLK2 | 1.01317788 |
| 36 | ILK | 0.99835684 |
| 37 | NEK1 | 0.99107871 |
| 38 | INSRR | 0.97873856 |
| 39 | TGFBR2 | 0.94500873 |
| 40 | MAP4K1 | 0.91868617 |
| 41 | FRK | 0.90432774 |
| 42 | TEC | 0.90407959 |
| 43 | CCNB1 | 0.87598642 |
| 44 | OXSR1 | 0.86620472 |
| 45 | FES | 0.83149187 |
| 46 | PRKCQ | 0.82701990 |
| 47 | STK39 | 0.81255203 |
| 48 | PAK4 | 0.79953123 |
| 49 | PDK2 | 0.77725593 |
| 50 | ARAF | 0.76878923 |
| 51 | LCK | 0.76756315 |
| 52 | MAPKAPK3 | 0.76136415 |
| 53 | CSNK1G3 | 0.70556802 |
| 54 | SRPK1 | 0.69583264 |
| 55 | ROCK1 | 0.67889240 |
| 56 | CSK | 0.64421181 |
| 57 | PIM2 | 0.63557322 |
| 58 | STK10 | 0.60284509 |
| 59 | ZAK | 0.58627551 |
| 60 | MOS | 0.58138041 |
| 61 | PRKCE | 0.57307415 |
| 62 | GRK5 | 0.57072831 |
| 63 | PLK3 | 0.56627411 |
| 64 | IKBKB | 0.56426139 |
| 65 | DAPK3 | 0.55525759 |
| 66 | MELK | 0.54671931 |
| 67 | TAF1 | 0.53907453 |
| 68 | CSNK1G2 | 0.53808669 |
| 69 | CSNK1A1L | 0.53417828 |
| 70 | GRK6 | 0.53378985 |
| 71 | NME1 | 0.53370420 |
| 72 | SYK | 0.52165540 |
| 73 | MST1R | 0.51648535 |
| 74 | IGF1R | 0.50749051 |
| 75 | WNK4 | 0.50313318 |
| 76 | PAK1 | 0.49221191 |
| 77 | BLK | 0.47920020 |
| 78 | PAK3 | 0.47620943 |
| 79 | LYN | 0.46847188 |
| 80 | TNK2 | 0.46837562 |
| 81 | CSF1R | 0.44981812 |
| 82 | CSNK1G1 | 0.44930080 |
| 83 | MAP3K11 | 0.44296553 |
| 84 | CDK9 | 0.38996820 |
| 85 | OBSCN | 0.38513909 |
| 86 | ABL1 | 0.38402221 |
| 87 | INSR | 0.38315344 |
| 88 | CAMK2A | 0.38177053 |
| 89 | FGFR1 | 0.37639009 |
| 90 | TAOK3 | 0.36989960 |
| 91 | FER | 0.36826452 |
| 92 | ERBB4 | 0.36807760 |
| 93 | TRPM7 | 0.35759760 |
| 94 | PRKCA | 0.35077817 |
| 95 | CSNK2A1 | 0.34119432 |
| 96 | AURKA | 0.33944253 |
| 97 | MAP2K6 | 0.32754442 |
| 98 | EGFR | 0.32522560 |
| 99 | ZAP70 | 0.32029242 |
| 100 | EIF2AK2 | 0.31575819 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 6.17428446 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.44974891 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.42508918 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.23214622 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.01933913 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.95482310 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.94460408 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.78662901 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.69042924 |
| 10 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.37073249 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.27370730 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.24759270 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.10763528 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.03977119 |
| 15 | Asthma_Homo sapiens_hsa05310 | 1.88820300 |
| 16 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.85773713 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.77537531 |
| 18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.76504851 |
| 19 | Viral myocarditis_Homo sapiens_hsa05416 | 1.75673604 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.65884106 |
| 21 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.65382071 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.52996340 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.50546826 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.48013374 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.38309627 |
| 26 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.37167254 |
| 27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.35356602 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.20623217 |
| 29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.13814246 |
| 30 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.12401493 |
| 31 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.12074217 |
| 32 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.09606281 |
| 33 | Salmonella infection_Homo sapiens_hsa05132 | 1.07691725 |
| 34 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.00107083 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.94674797 |
| 36 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.90279455 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.90102512 |
| 38 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.88451355 |
| 39 | Shigellosis_Homo sapiens_hsa05131 | 0.82973962 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.82356950 |
| 41 | Phototransduction_Homo sapiens_hsa04744 | 0.76138946 |
| 42 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.73730343 |
| 43 | Measles_Homo sapiens_hsa05162 | 0.73214192 |
| 44 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.72363872 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 0.68096512 |
| 46 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.66075185 |
| 47 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.65494787 |
| 48 | Homologous recombination_Homo sapiens_hsa03440 | 0.63179293 |
| 49 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61923506 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61107778 |
| 51 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.60533210 |
| 52 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58722997 |
| 53 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.58330732 |
| 54 | Malaria_Homo sapiens_hsa05144 | 0.56054778 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.54007153 |
| 56 | Legionellosis_Homo sapiens_hsa05134 | 0.53015999 |
| 57 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.52533195 |
| 58 | Basal transcription factors_Homo sapiens_hsa03022 | 0.52428481 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50879299 |
| 60 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48630049 |
| 61 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.47668504 |
| 62 | Pertussis_Homo sapiens_hsa05133 | 0.47514256 |
| 63 | Mismatch repair_Homo sapiens_hsa03430 | 0.47129462 |
| 64 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46728351 |
| 65 | RNA degradation_Homo sapiens_hsa03018 | 0.46345567 |
| 66 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.44944428 |
| 67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.44939264 |
| 68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44338881 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.43104944 |
| 70 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.42582502 |
| 71 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.42362684 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.42025604 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.39884191 |
| 74 | Ribosome_Homo sapiens_hsa03010 | 0.38248787 |
| 75 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.37682049 |
| 76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37351287 |
| 77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.36630917 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35619880 |
| 79 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.35261747 |
| 80 | Phagosome_Homo sapiens_hsa04145 | 0.35042814 |
| 81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.33748136 |
| 82 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.33580253 |
| 83 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33222015 |
| 84 | Leishmaniasis_Homo sapiens_hsa05140 | 0.33020830 |
| 85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.31687410 |
| 86 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30969546 |
| 87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.28064101 |
| 88 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.27190731 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.27031238 |
| 90 | RNA transport_Homo sapiens_hsa03013 | 0.25925451 |
| 91 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.25546136 |
| 92 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.24971433 |
| 93 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24911903 |
| 94 | DNA replication_Homo sapiens_hsa03030 | 0.24872187 |
| 95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24104325 |
| 96 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.23989904 |
| 97 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.23085828 |
| 98 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.22225413 |
| 99 | Tuberculosis_Homo sapiens_hsa05152 | 0.21502056 |
| 100 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.21231052 |

