

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.33236461 |
| 2 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.94792635 |
| 3 | DNA deamination (GO:0045006) | 4.62913960 |
| 4 | L-methionine biosynthetic process (GO:0071265) | 4.21537030 |
| 5 | amino acid salvage (GO:0043102) | 4.21537030 |
| 6 | L-methionine salvage (GO:0071267) | 4.21537030 |
| 7 | regulation of hexokinase activity (GO:1903299) | 3.92092306 |
| 8 | regulation of glucokinase activity (GO:0033131) | 3.92092306 |
| 9 | lactate metabolic process (GO:0006089) | 3.91905321 |
| 10 | cytidine deamination (GO:0009972) | 3.81123603 |
| 11 | cytidine metabolic process (GO:0046087) | 3.81123603 |
| 12 | cytidine catabolic process (GO:0006216) | 3.81123603 |
| 13 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.80018621 |
| 14 | protein deneddylation (GO:0000338) | 3.76042941 |
| 15 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.73854756 |
| 16 | regulation of DNA endoreduplication (GO:0032875) | 3.72660654 |
| 17 | cullin deneddylation (GO:0010388) | 3.61717162 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.58244059 |
| 19 | maturation of 5.8S rRNA (GO:0000460) | 3.57108255 |
| 20 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.55670289 |
| 21 | ribosome assembly (GO:0042255) | 3.54153516 |
| 22 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.49319250 |
| 23 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.44869990 |
| 24 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 3.44217812 |
| 25 | inositol phosphate dephosphorylation (GO:0046855) | 3.44217812 |
| 26 | protein complex biogenesis (GO:0070271) | 3.44122066 |
| 27 | cellular response to interleukin-15 (GO:0071350) | 3.41059769 |
| 28 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.40985749 |
| 29 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.40985749 |
| 30 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.40985749 |
| 31 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.40978245 |
| 32 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.37276058 |
| 33 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.37276058 |
| 34 | protein polyglutamylation (GO:0018095) | 3.37074133 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.34194075 |
| 36 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.34194075 |
| 37 | NADH dehydrogenase complex assembly (GO:0010257) | 3.34194075 |
| 38 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.32551650 |
| 39 | inositol phosphate catabolic process (GO:0071545) | 3.29785740 |
| 40 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.29199303 |
| 41 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.29199303 |
| 42 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.23756054 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.22058135 |
| 44 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.19319491 |
| 45 | protein neddylation (GO:0045116) | 3.16295115 |
| 46 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.15816842 |
| 47 | UMP metabolic process (GO:0046049) | 3.15816842 |
| 48 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.15816842 |
| 49 | UMP biosynthetic process (GO:0006222) | 3.15816842 |
| 50 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.14724343 |
| 51 | negative regulation of ligase activity (GO:0051352) | 3.14724343 |
| 52 | glucosamine-containing compound catabolic process (GO:1901072) | 3.14223675 |
| 53 | DNA double-strand break processing (GO:0000729) | 3.13843805 |
| 54 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.09027623 |
| 55 | positive regulation of osteoclast differentiation (GO:0045672) | 2.99067584 |
| 56 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.96943038 |
| 57 | termination of RNA polymerase III transcription (GO:0006386) | 2.92056665 |
| 58 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.92056665 |
| 59 | C-terminal protein lipidation (GO:0006501) | 2.90799639 |
| 60 | protein import into peroxisome matrix (GO:0016558) | 2.88022688 |
| 61 | protein-cofactor linkage (GO:0018065) | 2.87868174 |
| 62 | nucleoside diphosphate catabolic process (GO:0009134) | 2.86844589 |
| 63 | monocyte chemotaxis (GO:0002548) | 2.86532449 |
| 64 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.85981853 |
| 65 | chaperone-mediated protein transport (GO:0072321) | 2.84174406 |
| 66 | viral mRNA export from host cell nucleus (GO:0046784) | 2.84171191 |
| 67 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.82152645 |
| 68 | DNA ligation (GO:0006266) | 2.81926382 |
| 69 | response to gravity (GO:0009629) | 2.81067285 |
| 70 | replication fork processing (GO:0031297) | 2.80467970 |
| 71 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.78658549 |
| 72 | regulation of podosome assembly (GO:0071801) | 2.76395961 |
| 73 | positive regulation of ligase activity (GO:0051351) | 2.75666947 |
| 74 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.73376128 |
| 75 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.73324786 |
| 76 | positive regulation of cell cycle arrest (GO:0071158) | 2.73015647 |
| 77 | regulation of mitochondrial translation (GO:0070129) | 2.72604555 |
| 78 | respiratory chain complex IV assembly (GO:0008535) | 2.72603834 |
| 79 | GPI anchor biosynthetic process (GO:0006506) | 2.71237742 |
| 80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.70918277 |
| 81 | aldehyde catabolic process (GO:0046185) | 2.70011927 |
| 82 | S-adenosylmethionine metabolic process (GO:0046500) | 2.69160186 |
| 83 | intracellular protein transmembrane import (GO:0044743) | 2.67276049 |
| 84 | protein K11-linked deubiquitination (GO:0035871) | 2.66414337 |
| 85 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.66099578 |
| 86 | negative regulation of neurological system process (GO:0031645) | 2.65134411 |
| 87 | regulation of fibroblast apoptotic process (GO:2000269) | 2.64317405 |
| 88 | artery smooth muscle contraction (GO:0014824) | 2.62868310 |
| 89 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 2.62767308 |
| 90 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 2.62767308 |
| 91 | GPI anchor metabolic process (GO:0006505) | 2.62531538 |
| 92 | platelet dense granule organization (GO:0060155) | 2.62490225 |
| 93 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.59116875 |
| 94 | cytochrome complex assembly (GO:0017004) | 2.57064244 |
| 95 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.55945897 |
| 96 | ATP synthesis coupled proton transport (GO:0015986) | 2.55945897 |
| 97 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.55508238 |
| 98 | methionine biosynthetic process (GO:0009086) | 2.53947688 |
| 99 | regulation of cellular amine metabolic process (GO:0033238) | 2.53699519 |
| 100 | positive regulation of organelle assembly (GO:1902117) | 2.53512202 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.86808831 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.25131988 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.94651190 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.45799608 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.42844736 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.79571326 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.59558228 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.55301026 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.54475570 |
| 10 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.46631001 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.40095286 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.20668164 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.12039602 |
| 14 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.12016992 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.09897973 |
| 16 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.07388040 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.07025868 |
| 18 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.00709869 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 1.98956179 |
| 20 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.98376825 |
| 21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.98206538 |
| 22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.95377783 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.92419278 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.89434542 |
| 25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.85920181 |
| 26 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.80943109 |
| 27 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.80269921 |
| 28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.77352721 |
| 29 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.74580865 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.72990642 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.72548048 |
| 32 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.71198625 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.70644604 |
| 34 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.68254766 |
| 35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.65238124 |
| 36 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.61484536 |
| 37 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.60341755 |
| 38 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.60055811 |
| 39 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.56688229 |
| 40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.51863654 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.35915176 |
| 42 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.34799184 |
| 43 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31623829 |
| 44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.31133194 |
| 45 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.29390546 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.28387711 |
| 47 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.27189807 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25185496 |
| 49 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21685394 |
| 50 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21685394 |
| 51 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.21038971 |
| 52 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.17027681 |
| 53 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.15627759 |
| 54 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.15100118 |
| 55 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.13683086 |
| 56 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.12667322 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.12234240 |
| 58 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11503928 |
| 59 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.10287907 |
| 60 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.10055263 |
| 61 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10001795 |
| 62 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.09386380 |
| 63 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.09386380 |
| 64 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.09150663 |
| 65 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.09067517 |
| 66 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08696614 |
| 67 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.08471689 |
| 68 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.07937862 |
| 69 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.06574997 |
| 70 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.04794143 |
| 71 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04505794 |
| 72 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.04243133 |
| 73 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03419723 |
| 74 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.01792771 |
| 75 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.01260116 |
| 76 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.01205953 |
| 77 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.00777555 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99537933 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99537933 |
| 80 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.99107801 |
| 81 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.98617477 |
| 82 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.97072093 |
| 83 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.96897499 |
| 84 | GATA3_26560356_Chip-Seq_TH1_Human | 0.95965079 |
| 85 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95159363 |
| 86 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.95040799 |
| 87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94933452 |
| 88 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94265507 |
| 89 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93636968 |
| 90 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.93295159 |
| 91 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.93166461 |
| 92 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92507536 |
| 93 | GATA3_26560356_Chip-Seq_TH2_Human | 0.92007964 |
| 94 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91800951 |
| 95 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.91711054 |
| 96 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91634597 |
| 97 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.91317830 |
| 98 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.91211908 |
| 99 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.90174674 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89652833 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.58762964 |
| 2 | MP0001835_abnormal_antigen_presentation | 2.83550974 |
| 3 | MP0003786_premature_aging | 2.75814386 |
| 4 | MP0003195_calcinosis | 2.63923962 |
| 5 | MP0010307_abnormal_tumor_latency | 2.48273982 |
| 6 | MP0003011_delayed_dark_adaptation | 2.45792501 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.32543453 |
| 8 | MP0001984_abnormal_olfaction | 2.25910663 |
| 9 | MP0003878_abnormal_ear_physiology | 2.19571648 |
| 10 | MP0005377_hearing/vestibular/ear_phenot | 2.19571648 |
| 11 | MP0005084_abnormal_gallbladder_morpholo | 2.15406958 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 2.13835260 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.03816848 |
| 14 | MP0001873_stomach_inflammation | 2.01027716 |
| 15 | MP0008057_abnormal_DNA_replication | 1.88018399 |
| 16 | MP0010094_abnormal_chromosome_stability | 1.85596055 |
| 17 | MP0002277_abnormal_respiratory_mucosa | 1.80458574 |
| 18 | MP0009785_altered_susceptibility_to | 1.79238001 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 1.79220590 |
| 20 | MP0002163_abnormal_gland_morphology | 1.79199883 |
| 21 | MP0000685_abnormal_immune_system | 1.78382860 |
| 22 | MP0003950_abnormal_plasma_membrane | 1.76828139 |
| 23 | MP0004145_abnormal_muscle_electrophysio | 1.75235286 |
| 24 | MP0008875_abnormal_xenobiotic_pharmacok | 1.71468716 |
| 25 | MP0003646_muscle_fatigue | 1.70558742 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.69990354 |
| 27 | MP0004885_abnormal_endolymph | 1.67692613 |
| 28 | MP0002638_abnormal_pupillary_reflex | 1.64169771 |
| 29 | MP0001188_hyperpigmentation | 1.61900573 |
| 30 | MP0001542_abnormal_bone_strength | 1.59606974 |
| 31 | MP0005000_abnormal_immune_tolerance | 1.53871503 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.52835754 |
| 33 | MP0008058_abnormal_DNA_repair | 1.44112922 |
| 34 | MP0002095_abnormal_skin_pigmentation | 1.43614513 |
| 35 | MP0002006_tumorigenesis | 1.40166553 |
| 36 | MP0008872_abnormal_physiological_respon | 1.39490174 |
| 37 | MP0001800_abnormal_humoral_immune | 1.38534514 |
| 38 | MP0001905_abnormal_dopamine_level | 1.35716230 |
| 39 | MP0000013_abnormal_adipose_tissue | 1.35149560 |
| 40 | MP0002405_respiratory_system_inflammati | 1.34902342 |
| 41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.32569269 |
| 42 | MP0002876_abnormal_thyroid_physiology | 1.31665201 |
| 43 | MP0002736_abnormal_nociception_after | 1.29755788 |
| 44 | MP0004782_abnormal_surfactant_physiolog | 1.29317707 |
| 45 | MP0002166_altered_tumor_susceptibility | 1.27647049 |
| 46 | MP0002160_abnormal_reproductive_system | 1.26995295 |
| 47 | MP0004147_increased_porphyrin_level | 1.24246321 |
| 48 | MP0002075_abnormal_coat/hair_pigmentati | 1.22204032 |
| 49 | MP0003718_maternal_effect | 1.22116274 |
| 50 | MP0001501_abnormal_sleep_pattern | 1.21704108 |
| 51 | MP0002148_abnormal_hypersensitivity_rea | 1.15868673 |
| 52 | MP0000613_abnormal_salivary_gland | 1.15268370 |
| 53 | MP0000371_diluted_coat_color | 1.13355879 |
| 54 | MP0000372_irregular_coat_pigmentation | 1.13212917 |
| 55 | MP0009764_decreased_sensitivity_to | 1.10067573 |
| 56 | MP0001661_extended_life_span | 1.07792339 |
| 57 | MP0005075_abnormal_melanosome_morpholog | 1.07206316 |
| 58 | MP0001243_abnormal_dermal_layer | 1.07047473 |
| 59 | MP0010234_abnormal_vibrissa_follicle | 1.06747848 |
| 60 | MP0002723_abnormal_immune_serum | 1.06328724 |
| 61 | MP0002837_dystrophic_cardiac_calcinosis | 1.04442157 |
| 62 | MP0005389_reproductive_system_phenotype | 1.02619474 |
| 63 | MP0000516_abnormal_urinary_system | 1.02292256 |
| 64 | MP0005367_renal/urinary_system_phenotyp | 1.02292256 |
| 65 | MP0000427_abnormal_hair_cycle | 0.99642671 |
| 66 | MP0002933_joint_inflammation | 0.99633932 |
| 67 | MP0001186_pigmentation_phenotype | 0.99382288 |
| 68 | MP0000689_abnormal_spleen_morphology | 0.98490367 |
| 69 | MP0008007_abnormal_cellular_replicative | 0.98227987 |
| 70 | MP0002693_abnormal_pancreas_physiology | 0.95287493 |
| 71 | MP0002102_abnormal_ear_morphology | 0.93341849 |
| 72 | MP0006276_abnormal_autonomic_nervous | 0.92252168 |
| 73 | MP0001853_heart_inflammation | 0.91815523 |
| 74 | MP0009745_abnormal_behavioral_response | 0.91285835 |
| 75 | MP0002938_white_spotting | 0.89354440 |
| 76 | MP0005310_abnormal_salivary_gland | 0.88492579 |
| 77 | MP0000703_abnormal_thymus_morphology | 0.88128213 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 0.86913921 |
| 79 | MP0003283_abnormal_digestive_organ | 0.86761419 |
| 80 | MP0005332_abnormal_amino_acid | 0.86722484 |
| 81 | MP0005253_abnormal_eye_physiology | 0.84674500 |
| 82 | MP0001819_abnormal_immune_cell | 0.84261403 |
| 83 | MP0005645_abnormal_hypothalamus_physiol | 0.84127748 |
| 84 | MP0005410_abnormal_fertilization | 0.84099070 |
| 85 | MP0001790_abnormal_immune_system | 0.83724772 |
| 86 | MP0005387_immune_system_phenotype | 0.83724772 |
| 87 | MP0002420_abnormal_adaptive_immunity | 0.83152698 |
| 88 | MP0003806_abnormal_nucleotide_metabolis | 0.82025456 |
| 89 | MP0006036_abnormal_mitochondrial_physio | 0.81536534 |
| 90 | MP0003183_abnormal_peptide_metabolism | 0.80895840 |
| 91 | MP0003724_increased_susceptibility_to | 0.78723690 |
| 92 | MP0004036_abnormal_muscle_relaxation | 0.78439205 |
| 93 | MP0005379_endocrine/exocrine_gland_phen | 0.77920777 |
| 94 | MP0002722_abnormal_immune_system | 0.77481803 |
| 95 | MP0002272_abnormal_nervous_system | 0.77013396 |
| 96 | MP0003763_abnormal_thymus_physiology | 0.75821254 |
| 97 | MP0001119_abnormal_female_reproductive | 0.73184510 |
| 98 | MP0002398_abnormal_bone_marrow | 0.71679790 |
| 99 | MP0005174_abnormal_tail_pigmentation | 0.71375990 |
| 100 | MP0000716_abnormal_immune_system | 0.70360591 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 4.17093032 |
| 2 | Large for gestational age (HP:0001520) | 4.06587283 |
| 3 | IgG deficiency (HP:0004315) | 3.83074343 |
| 4 | Abnormality of T cell number (HP:0011839) | 3.79584222 |
| 5 | Thyroiditis (HP:0100646) | 3.67260772 |
| 6 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.34332770 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.32908252 |
| 8 | Severe combined immunodeficiency (HP:0004430) | 3.26952649 |
| 9 | Abnormality of the pons (HP:0007361) | 3.23276780 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.20847348 |
| 11 | Type I transferrin isoform profile (HP:0003642) | 3.18668310 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.18189936 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.08551546 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.04982912 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 3.00095756 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.00095756 |
| 17 | Increased CSF lactate (HP:0002490) | 2.95292202 |
| 18 | Conjunctival hamartoma (HP:0100780) | 2.91807845 |
| 19 | Abolished electroretinogram (ERG) (HP:0000550) | 2.91419796 |
| 20 | Hypoglycemic seizures (HP:0002173) | 2.90047825 |
| 21 | Abnormality of T cells (HP:0002843) | 2.88356260 |
| 22 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.84448046 |
| 23 | Acute encephalopathy (HP:0006846) | 2.80938529 |
| 24 | Hypoproteinemia (HP:0003075) | 2.80544319 |
| 25 | Pancreatic cysts (HP:0001737) | 2.80143142 |
| 26 | Stomatitis (HP:0010280) | 2.79545832 |
| 27 | Increased hepatocellular lipid droplets (HP:0006565) | 2.76696826 |
| 28 | Anhidrosis (HP:0000970) | 2.72235191 |
| 29 | Methylmalonic acidemia (HP:0002912) | 2.61816947 |
| 30 | Hypoplasia of the thymus (HP:0000778) | 2.61788020 |
| 31 | Ketoacidosis (HP:0001993) | 2.59460539 |
| 32 | Hepatic necrosis (HP:0002605) | 2.58777318 |
| 33 | Hepatocellular necrosis (HP:0001404) | 2.57727815 |
| 34 | Reduced antithrombin III activity (HP:0001976) | 2.56432570 |
| 35 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.56225876 |
| 36 | Lipid accumulation in hepatocytes (HP:0006561) | 2.52905528 |
| 37 | Nephronophthisis (HP:0000090) | 2.52830032 |
| 38 | Short tibia (HP:0005736) | 2.35487262 |
| 39 | Abnormality of eosinophils (HP:0001879) | 2.34592122 |
| 40 | Combined immunodeficiency (HP:0005387) | 2.32918767 |
| 41 | Methylmalonic aciduria (HP:0012120) | 2.28155932 |
| 42 | Brushfield spots (HP:0001088) | 2.27633291 |
| 43 | Palpebral edema (HP:0100540) | 2.24707047 |
| 44 | Abnormality of macular pigmentation (HP:0008002) | 2.24253255 |
| 45 | Hypothermia (HP:0002045) | 2.23339999 |
| 46 | Abnormality of the renal cortex (HP:0011035) | 2.22431492 |
| 47 | Cerebral edema (HP:0002181) | 2.20209564 |
| 48 | Tongue fasciculations (HP:0001308) | 2.19482318 |
| 49 | Increased serum lactate (HP:0002151) | 2.17893153 |
| 50 | Pancreatic fibrosis (HP:0100732) | 2.17186911 |
| 51 | Abnormal glycosylation (HP:0012345) | 2.16941596 |
| 52 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.16941596 |
| 53 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.16941596 |
| 54 | Abnormal protein glycosylation (HP:0012346) | 2.16941596 |
| 55 | True hermaphroditism (HP:0010459) | 2.16887279 |
| 56 | Attenuation of retinal blood vessels (HP:0007843) | 2.16152021 |
| 57 | Respiratory failure (HP:0002878) | 2.12998935 |
| 58 | Ketosis (HP:0001946) | 2.12888258 |
| 59 | Renal cortical cysts (HP:0000803) | 2.12701690 |
| 60 | Optic disc pallor (HP:0000543) | 2.12597125 |
| 61 | Prominent metopic ridge (HP:0005487) | 2.12129432 |
| 62 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.11291293 |
| 63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.10210346 |
| 64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.10076767 |
| 65 | Medial flaring of the eyebrow (HP:0010747) | 2.06834941 |
| 66 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.06740678 |
| 67 | Furrowed tongue (HP:0000221) | 2.05766956 |
| 68 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.01561126 |
| 69 | Abnormality of renal resorption (HP:0011038) | 1.98831387 |
| 70 | Lactic acidosis (HP:0003128) | 1.98263817 |
| 71 | Epiphyseal stippling (HP:0010655) | 1.96665900 |
| 72 | Congenital stationary night blindness (HP:0007642) | 1.95648682 |
| 73 | Abnormality of the renal collecting system (HP:0004742) | 1.95361634 |
| 74 | Pulmonary fibrosis (HP:0002206) | 1.92093938 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.91927407 |
| 76 | Duplicated collecting system (HP:0000081) | 1.91385066 |
| 77 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.90818472 |
| 78 | Exercise intolerance (HP:0003546) | 1.90781573 |
| 79 | Hamartoma of the eye (HP:0010568) | 1.90015472 |
| 80 | Cortical visual impairment (HP:0100704) | 1.88577777 |
| 81 | Increased serum pyruvate (HP:0003542) | 1.87984807 |
| 82 | Symptomatic seizures (HP:0011145) | 1.87041630 |
| 83 | Hyperglycemia (HP:0003074) | 1.86220544 |
| 84 | Brittle hair (HP:0002299) | 1.84968142 |
| 85 | Pendular nystagmus (HP:0012043) | 1.84316247 |
| 86 | Proximal tubulopathy (HP:0000114) | 1.83872265 |
| 87 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.83784916 |
| 88 | Abnormality of the metopic suture (HP:0005556) | 1.83664841 |
| 89 | Constricted visual fields (HP:0001133) | 1.83038638 |
| 90 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.82859382 |
| 91 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.81070213 |
| 92 | Muscle fibrillation (HP:0010546) | 1.76474663 |
| 93 | Eosinophilia (HP:0001880) | 1.76230556 |
| 94 | Hyperphosphaturia (HP:0003109) | 1.76184562 |
| 95 | Porencephaly (HP:0002132) | 1.74960088 |
| 96 | Melanoma (HP:0002861) | 1.73544712 |
| 97 | Delayed CNS myelination (HP:0002188) | 1.73313835 |
| 98 | Abnormality of the prostate (HP:0008775) | 1.72935323 |
| 99 | Abnormality of B cell number (HP:0010975) | 1.72797572 |
| 100 | Lethargy (HP:0001254) | 1.72511283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.05467088 |
| 2 | EIF2AK3 | 4.56844254 |
| 3 | FRK | 3.45738243 |
| 4 | TSSK6 | 3.22331196 |
| 5 | VRK2 | 2.84457655 |
| 6 | MST4 | 2.58609125 |
| 7 | MAP3K12 | 2.56357714 |
| 8 | NUAK1 | 2.54378089 |
| 9 | NME1 | 2.40735708 |
| 10 | EIF2AK1 | 1.97772707 |
| 11 | BUB1 | 1.97518068 |
| 12 | LIMK1 | 1.90864174 |
| 13 | NEK1 | 1.76414117 |
| 14 | PLK3 | 1.68321091 |
| 15 | ZAK | 1.67151983 |
| 16 | GRK1 | 1.64142533 |
| 17 | ADRBK2 | 1.61543941 |
| 18 | PIM2 | 1.45381487 |
| 19 | OXSR1 | 1.44902787 |
| 20 | CSNK1G3 | 1.36467046 |
| 21 | VRK1 | 1.34227627 |
| 22 | TRIM28 | 1.33887465 |
| 23 | BCR | 1.31534269 |
| 24 | BCKDK | 1.30299143 |
| 25 | CSNK1G1 | 1.30076782 |
| 26 | EIF2AK2 | 1.29241472 |
| 27 | PLK2 | 1.26647997 |
| 28 | TAF1 | 1.23796722 |
| 29 | KDR | 1.17944442 |
| 30 | CSNK1A1L | 1.14228762 |
| 31 | NME2 | 1.11772467 |
| 32 | FGFR2 | 1.11305668 |
| 33 | DAPK1 | 1.06093037 |
| 34 | STK39 | 1.02594605 |
| 35 | ERBB3 | 1.02139929 |
| 36 | TLK1 | 1.01449698 |
| 37 | MAP2K6 | 1.00880573 |
| 38 | MAPKAPK3 | 1.00526371 |
| 39 | MYLK | 1.00482907 |
| 40 | CSNK1G2 | 0.98688581 |
| 41 | TESK1 | 0.95231111 |
| 42 | PBK | 0.92133604 |
| 43 | WNK3 | 0.91233357 |
| 44 | FLT3 | 0.90300111 |
| 45 | SRPK1 | 0.88283652 |
| 46 | PASK | 0.86440447 |
| 47 | PHKG1 | 0.86313853 |
| 48 | PHKG2 | 0.86313853 |
| 49 | BRSK2 | 0.85957560 |
| 50 | PDK2 | 0.85825890 |
| 51 | PRKCI | 0.81650768 |
| 52 | ALK | 0.77196224 |
| 53 | PRKD3 | 0.75523262 |
| 54 | SYK | 0.74269585 |
| 55 | PIK3CG | 0.73038243 |
| 56 | STK16 | 0.71519549 |
| 57 | PRKCQ | 0.70318916 |
| 58 | GRK5 | 0.65931969 |
| 59 | IRAK4 | 0.64853194 |
| 60 | CAMKK2 | 0.62084988 |
| 61 | WNK4 | 0.61892465 |
| 62 | MAP4K2 | 0.61866534 |
| 63 | PRKCE | 0.61807946 |
| 64 | KIT | 0.59596794 |
| 65 | CDK19 | 0.52031425 |
| 66 | IKBKB | 0.49504485 |
| 67 | PIM1 | 0.47515214 |
| 68 | MAP4K1 | 0.45347902 |
| 69 | OBSCN | 0.44559601 |
| 70 | LCK | 0.43230864 |
| 71 | BRSK1 | 0.39794299 |
| 72 | PINK1 | 0.39710889 |
| 73 | CSNK1A1 | 0.38499608 |
| 74 | INSRR | 0.37758183 |
| 75 | CDK3 | 0.37244235 |
| 76 | SCYL2 | 0.36730433 |
| 77 | LYN | 0.34621926 |
| 78 | PRKCG | 0.34383776 |
| 79 | IGF1R | 0.34380335 |
| 80 | MARK3 | 0.34151028 |
| 81 | TIE1 | 0.33924558 |
| 82 | STK11 | 0.32305478 |
| 83 | TEC | 0.32260414 |
| 84 | TNK2 | 0.31424283 |
| 85 | DYRK2 | 0.30532674 |
| 86 | MKNK1 | 0.30470047 |
| 87 | DAPK3 | 0.30261368 |
| 88 | CSNK2A1 | 0.28763696 |
| 89 | MAPK7 | 0.28760141 |
| 90 | GRK7 | 0.27166892 |
| 91 | FGFR1 | 0.26861643 |
| 92 | ABL1 | 0.26295391 |
| 93 | ITK | 0.26178097 |
| 94 | GRK6 | 0.25716666 |
| 95 | CSNK2A2 | 0.25376263 |
| 96 | CCNB1 | 0.25048993 |
| 97 | STK3 | 0.24311274 |
| 98 | ATR | 0.23842754 |
| 99 | ARAF | 0.23780460 |
| 100 | MAP3K14 | 0.23295248 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.29038807 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.12867930 |
| 3 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.72855625 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.70753660 |
| 5 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.53439361 |
| 6 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.23530052 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.20368672 |
| 8 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.13236351 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.00508040 |
| 10 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.94994901 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 1.93853154 |
| 12 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.93516501 |
| 13 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.91216644 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.89285207 |
| 15 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.87016763 |
| 16 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.85699545 |
| 17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.83011803 |
| 18 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.80063086 |
| 19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.76960049 |
| 20 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.70097479 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.68345044 |
| 22 | Parkinsons disease_Homo sapiens_hsa05012 | 1.64921127 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.62097988 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59508400 |
| 25 | Allograft rejection_Homo sapiens_hsa05330 | 1.55693016 |
| 26 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.50686124 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.44442925 |
| 28 | Peroxisome_Homo sapiens_hsa04146 | 1.43386880 |
| 29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.41216187 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.35913894 |
| 31 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.35799774 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.34872304 |
| 33 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.33500155 |
| 34 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.31709003 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30091858 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.29462743 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.28363260 |
| 38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.26100145 |
| 39 | RNA degradation_Homo sapiens_hsa03018 | 1.25762368 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.22411483 |
| 41 | Mismatch repair_Homo sapiens_hsa03430 | 1.19347808 |
| 42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.13676108 |
| 43 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.12406585 |
| 44 | DNA replication_Homo sapiens_hsa03030 | 1.11816478 |
| 45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.11732069 |
| 46 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.07115370 |
| 47 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.02904209 |
| 48 | Huntingtons disease_Homo sapiens_hsa05016 | 0.94922346 |
| 49 | Spliceosome_Homo sapiens_hsa03040 | 0.93829938 |
| 50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.89483871 |
| 51 | Alzheimers disease_Homo sapiens_hsa05010 | 0.86011627 |
| 52 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.85041292 |
| 53 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.84326953 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.84041611 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.82793117 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.81992436 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.77218275 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.76313585 |
| 59 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.74575952 |
| 60 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.74444520 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.74128314 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72158995 |
| 63 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.69815679 |
| 64 | Phototransduction_Homo sapiens_hsa04744 | 0.68237975 |
| 65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.67803070 |
| 66 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.66440301 |
| 67 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.66272658 |
| 68 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.63861656 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62412912 |
| 70 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.61328245 |
| 71 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.61103583 |
| 72 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.59936949 |
| 73 | Measles_Homo sapiens_hsa05162 | 0.59127168 |
| 74 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.58591344 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58004462 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.57989424 |
| 77 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.54613843 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.53864739 |
| 79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53365747 |
| 80 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.51067338 |
| 81 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49288452 |
| 82 | Sulfur relay system_Homo sapiens_hsa04122 | 0.47144904 |
| 83 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.44419910 |
| 84 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.42803235 |
| 85 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41869628 |
| 86 | Insulin secretion_Homo sapiens_hsa04911 | 0.40101682 |
| 87 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.38913605 |
| 88 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.38693298 |
| 89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.37042999 |
| 90 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35358319 |
| 91 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35029418 |
| 92 | Base excision repair_Homo sapiens_hsa03410 | 0.33932010 |
| 93 | Carbon metabolism_Homo sapiens_hsa01200 | 0.33729926 |
| 94 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.33499212 |
| 95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.31457923 |
| 96 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.30883050 |
| 97 | Circadian rhythm_Homo sapiens_hsa04710 | 0.29546729 |
| 98 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.28786685 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28721466 |
| 100 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.28345361 |

