Rank | Gene Set | Z-score |
---|---|---|
1 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.63949133 |
2 | L-phenylalanine catabolic process (GO:0006559) | 7.63949133 |
3 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.32075181 |
4 | L-phenylalanine metabolic process (GO:0006558) | 7.32075181 |
5 | aromatic amino acid family catabolic process (GO:0009074) | 6.80130873 |
6 | * protein-lipid complex assembly (GO:0065005) | 6.49184722 |
7 | * triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.23574562 |
8 | tryptophan catabolic process (GO:0006569) | 6.05546386 |
9 | indole-containing compound catabolic process (GO:0042436) | 6.05546386 |
10 | indolalkylamine catabolic process (GO:0046218) | 6.05546386 |
11 | kynurenine metabolic process (GO:0070189) | 5.96614580 |
12 | bile acid biosynthetic process (GO:0006699) | 5.88107634 |
13 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 5.86393319 |
14 | glyoxylate metabolic process (GO:0046487) | 5.79370454 |
15 | negative regulation of fibrinolysis (GO:0051918) | 5.77803549 |
16 | alpha-linolenic acid metabolic process (GO:0036109) | 5.75578005 |
17 | tryptophan metabolic process (GO:0006568) | 5.72217384 |
18 | intestinal cholesterol absorption (GO:0030299) | 5.67906148 |
19 | urea cycle (GO:0000050) | 5.67568393 |
20 | urea metabolic process (GO:0019627) | 5.67568393 |
21 | * high-density lipoprotein particle remodeling (GO:0034375) | 5.59444969 |
22 | regulation of fibrinolysis (GO:0051917) | 5.52604131 |
23 | regulation of plasminogen activation (GO:0010755) | 5.44925723 |
24 | protein carboxylation (GO:0018214) | 5.44659086 |
25 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.44659086 |
26 | sulfur amino acid catabolic process (GO:0000098) | 5.42437677 |
27 | cysteine metabolic process (GO:0006534) | 5.39012150 |
28 | * protein-lipid complex subunit organization (GO:0071825) | 5.33146468 |
29 | nitrogen cycle metabolic process (GO:0071941) | 5.21971830 |
30 | serine family amino acid catabolic process (GO:0009071) | 5.18754085 |
31 | regulation of protein activation cascade (GO:2000257) | 5.13405716 |
32 | bile acid metabolic process (GO:0008206) | 5.09728277 |
33 | complement activation, alternative pathway (GO:0006957) | 5.08999064 |
34 | * low-density lipoprotein particle remodeling (GO:0034374) | 5.03522719 |
35 | regulation of triglyceride catabolic process (GO:0010896) | 5.01825098 |
36 | aromatic amino acid family metabolic process (GO:0009072) | 4.95573554 |
37 | tyrosine metabolic process (GO:0006570) | 4.87253170 |
38 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.85290595 |
39 | * reverse cholesterol transport (GO:0043691) | 4.82500682 |
40 | * plasma lipoprotein particle remodeling (GO:0034369) | 4.82438120 |
41 | * protein-lipid complex remodeling (GO:0034368) | 4.82438120 |
42 | * macromolecular complex remodeling (GO:0034367) | 4.82438120 |
43 | acylglycerol homeostasis (GO:0055090) | 4.78648520 |
44 | triglyceride homeostasis (GO:0070328) | 4.78648520 |
45 | regulation of complement activation (GO:0030449) | 4.74924817 |
46 | homocysteine metabolic process (GO:0050667) | 4.72720776 |
47 | negative regulation of protein activation cascade (GO:2000258) | 4.68520971 |
48 | alpha-amino acid catabolic process (GO:1901606) | 4.67188390 |
49 | amino-acid betaine metabolic process (GO:0006577) | 4.65630035 |
50 | cellular ketone body metabolic process (GO:0046950) | 4.62615647 |
51 | negative regulation of blood coagulation (GO:0030195) | 4.59595808 |
52 | negative regulation of hemostasis (GO:1900047) | 4.59595808 |
53 | * regulation of cholesterol esterification (GO:0010872) | 4.57240058 |
54 | * negative regulation of lipase activity (GO:0060192) | 4.55962177 |
55 | lysine catabolic process (GO:0006554) | 4.55744877 |
56 | lysine metabolic process (GO:0006553) | 4.55744877 |
57 | glycine metabolic process (GO:0006544) | 4.45896058 |
58 | epoxygenase P450 pathway (GO:0019373) | 4.45491721 |
59 | * phospholipid efflux (GO:0033700) | 4.41520944 |
60 | bile acid and bile salt transport (GO:0015721) | 4.41032962 |
61 | * plasma lipoprotein particle clearance (GO:0034381) | 4.37450489 |
62 | regulation of apoptotic cell clearance (GO:2000425) | 4.37444537 |
63 | imidazole-containing compound metabolic process (GO:0052803) | 4.37175575 |
64 | * negative regulation of cholesterol transport (GO:0032375) | 4.35558874 |
65 | * negative regulation of sterol transport (GO:0032372) | 4.35558874 |
66 | coenzyme catabolic process (GO:0009109) | 4.32292166 |
67 | indolalkylamine metabolic process (GO:0006586) | 4.30396366 |
68 | cellular amino acid catabolic process (GO:0009063) | 4.29920772 |
69 | glutamate metabolic process (GO:0006536) | 4.27871435 |
70 | cellular glucuronidation (GO:0052695) | 4.26886293 |
71 | positive regulation of hemostasis (GO:1900048) | 4.24815568 |
72 | positive regulation of blood coagulation (GO:0030194) | 4.24815568 |
73 | negative regulation of coagulation (GO:0050819) | 4.22171364 |
74 | amine catabolic process (GO:0009310) | 4.21638932 |
75 | cellular biogenic amine catabolic process (GO:0042402) | 4.21638932 |
76 | * cholesterol efflux (GO:0033344) | 4.20707953 |
77 | serine family amino acid metabolic process (GO:0009069) | 4.20553699 |
78 | * lipoprotein metabolic process (GO:0042157) | 4.16810132 |
79 | regulation of humoral immune response (GO:0002920) | 4.15581122 |
80 | benzene-containing compound metabolic process (GO:0042537) | 4.12948502 |
81 | ethanol oxidation (GO:0006069) | 4.09426896 |
82 | acute-phase response (GO:0006953) | 4.08351072 |
83 | aldehyde catabolic process (GO:0046185) | 4.07986455 |
84 | cellular modified amino acid catabolic process (GO:0042219) | 4.07948968 |
85 | arginine metabolic process (GO:0006525) | 4.07857621 |
86 | drug catabolic process (GO:0042737) | 4.07105541 |
87 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.07066978 |
88 | serine family amino acid biosynthetic process (GO:0009070) | 4.07058448 |
89 | fibrinolysis (GO:0042730) | 4.06987466 |
90 | * cholesterol transport (GO:0030301) | 4.06040996 |
91 | * sterol transport (GO:0015918) | 4.06040996 |
92 | negative regulation of wound healing (GO:0061045) | 4.04764149 |
93 | ketone body metabolic process (GO:1902224) | 4.00609890 |
94 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.99486705 |
95 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.99486705 |
96 | exogenous drug catabolic process (GO:0042738) | 3.98212730 |
97 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.96761926 |
98 | blood coagulation, intrinsic pathway (GO:0007597) | 3.92456839 |
99 | * plasma lipoprotein particle assembly (GO:0034377) | 3.89547532 |
100 | proline metabolic process (GO:0006560) | 3.89325450 |
101 | positive regulation of coagulation (GO:0050820) | 3.88527890 |
102 | phospholipid homeostasis (GO:0055091) | 3.85982559 |
103 | cofactor catabolic process (GO:0051187) | 3.82357379 |
104 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 3.80274422 |
105 | omega-hydroxylase P450 pathway (GO:0097267) | 3.78880369 |
106 | glucuronate metabolic process (GO:0019585) | 3.78509644 |
107 | uronic acid metabolic process (GO:0006063) | 3.78509644 |
108 | organic acid catabolic process (GO:0016054) | 3.77930053 |
109 | carboxylic acid catabolic process (GO:0046395) | 3.77930053 |
110 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 3.76170586 |
111 | short-chain fatty acid metabolic process (GO:0046459) | 3.75852945 |
112 | * cholesterol homeostasis (GO:0042632) | 3.73626949 |
113 | * sterol homeostasis (GO:0055092) | 3.67255874 |
114 | regulation of bile acid biosynthetic process (GO:0070857) | 3.66869525 |
115 | protein activation cascade (GO:0072376) | 3.66019692 |
116 | acetyl-CoA metabolic process (GO:0006084) | 3.63515472 |
117 | regulation of cholesterol homeostasis (GO:2000188) | 3.63477245 |
118 | * plasma lipoprotein particle organization (GO:0071827) | 3.63006809 |
119 | regulation of lipoprotein particle clearance (GO:0010984) | 3.62209289 |
120 | complement activation, classical pathway (GO:0006958) | 3.62116043 |
121 | ethanol metabolic process (GO:0006067) | 3.60851919 |
122 | complement activation (GO:0006956) | 3.60567022 |
123 | * positive regulation of lipid catabolic process (GO:0050996) | 3.58683201 |
124 | NAD biosynthetic process (GO:0009435) | 3.58328046 |
125 | flavonoid metabolic process (GO:0009812) | 3.57176965 |
126 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 3.56367399 |
127 | pyridine nucleotide biosynthetic process (GO:0019363) | 3.56367399 |
128 | opsonization (GO:0008228) | 3.53867890 |
129 | intestinal absorption (GO:0050892) | 3.53175589 |
130 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.52457505 |
131 | drug metabolic process (GO:0017144) | 3.45015341 |
132 | negative regulation of complement activation (GO:0045916) | 3.44732286 |
133 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 3.41771260 |
134 | heme transport (GO:0015886) | 3.38972066 |
135 | * lipid homeostasis (GO:0055088) | 3.35215270 |
136 | * positive regulation of steroid metabolic process (GO:0045940) | 3.29720244 |
137 | cytolysis (GO:0019835) | 3.25879593 |
138 | peptidyl-glutamic acid modification (GO:0018200) | 3.23924189 |
139 | regulation of cholesterol biosynthetic process (GO:0045540) | 3.19623604 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.44756119 |
2 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.22938831 |
3 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 6.95203563 |
4 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.52127711 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.31113435 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.18864445 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.98748055 |
8 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 4.03929328 |
9 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.01554172 |
10 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.07893435 |
11 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.01521834 |
12 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.9562769 |
13 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.97572195 |
14 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.77028545 |
15 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.73118035 |
16 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.58662131 |
17 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.58044092 |
18 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.56179341 |
19 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.49917327 |
20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.46401684 |
21 | GATA1_22025678_ChIP-Seq_K562_Human | 1.44309908 |
22 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.40229166 |
23 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.29059648 |
24 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.19828014 |
25 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.17483647 |
26 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.14529544 |
27 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.12687680 |
28 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.11266857 |
29 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.05073172 |
30 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02300752 |
31 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.01394341 |
32 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.98533144 |
33 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.93744815 |
34 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.92433761 |
35 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.90602461 |
36 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.89409728 |
37 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.86396854 |
38 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.85311385 |
39 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.85021862 |
40 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.84018471 |
41 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.83440348 |
42 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.81750533 |
43 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.80978048 |
44 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.79727620 |
45 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.78136850 |
46 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77253743 |
47 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.77002285 |
48 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.76748717 |
49 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.76226847 |
50 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.75991379 |
51 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.75598703 |
52 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.74917678 |
53 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.74712933 |
54 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.74136932 |
55 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.71881315 |
56 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.71606514 |
57 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.70824390 |
58 | * SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.70026979 |
59 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.69999462 |
60 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.69682721 |
61 | TP53_16413492_ChIP-PET_HCT116_Human | 0.69275293 |
62 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.67181024 |
63 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.66584609 |
64 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.65124896 |
65 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.63955739 |
66 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.63859134 |
67 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.63855713 |
68 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.63844056 |
69 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.63192891 |
70 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.62434698 |
71 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.62334694 |
72 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.62072372 |
73 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.62072372 |
74 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.61788664 |
75 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.61450582 |
76 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.59835172 |
77 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.59418763 |
78 | * ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.59285608 |
79 | * ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.58394722 |
80 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.57903240 |
81 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.56425960 |
82 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.55938223 |
83 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.55463347 |
84 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.55014256 |
85 | * RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.54567566 |
86 | * OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.54198245 |
87 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.53357131 |
88 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.53249106 |
89 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.52855499 |
90 | * EOMES_21245162_ChIP-Seq_HESCs_Human | 0.52240390 |
91 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.52082703 |
92 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.52023474 |
93 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.51938360 |
94 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.51545097 |
95 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.51524218 |
96 | AR_20517297_ChIP-Seq_VCAP_Human | 0.51399514 |
97 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.51160374 |
98 | SOX11_22085726_ChIP-Seq_ESNs_Mouse | 0.50386598 |
99 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.49962989 |
100 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.49911226 |
101 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.49634079 |
102 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.49426533 |
103 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.49415743 |
104 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.48587719 |
105 | CBP_21632823_ChIP-Seq_H3396_Human | 0.47687588 |
106 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.47501335 |
107 | GATA1_19941826_ChIP-Seq_K562_Human | 0.46858850 |
108 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.46605927 |
109 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.46531488 |
110 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.46360333 |
111 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.45364282 |
112 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.43643212 |
113 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.42327984 |
114 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.41575875 |
115 | GATA2_19941826_ChIP-Seq_K562_Human | 0.41503630 |
116 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.41447759 |
117 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.40513328 |
118 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.40342806 |
119 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.40288447 |
120 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.40143524 |
121 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.40137899 |
122 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.38984824 |
123 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.38629189 |
124 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.38563244 |
125 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.38379992 |
126 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.37597368 |
127 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.37201143 |
128 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.36904782 |
129 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.36400295 |
130 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.36377135 |
131 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.34728897 |
132 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.34501948 |
133 | NCOR_22424771_ChIP-Seq_293T_Human | 0.33974866 |
134 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.33601234 |
135 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.33352905 |
136 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.33115520 |
137 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.33073451 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.43144764 |
2 | MP0005360_urolithiasis | 7.45762978 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.38732073 |
4 | MP0005365_abnormal_bile_salt | 6.21436265 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.21463606 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.24935053 |
7 | MP0003252_abnormal_bile_duct | 3.85284760 |
8 | * MP0010329_abnormal_lipoprotein_level | 3.55719258 |
9 | MP0009840_abnormal_foam_cell | 3.51398970 |
10 | MP0005083_abnormal_biliary_tract | 3.11329291 |
11 | MP0003122_maternal_imprinting | 2.97356721 |
12 | MP0003195_calcinosis | 2.84484103 |
13 | MP0005332_abnormal_amino_acid | 2.76098842 |
14 | MP0001666_abnormal_nutrient_absorption | 2.56559345 |
15 | MP0003191_abnormal_cellular_cholesterol | 2.40190307 |
16 | MP0000609_abnormal_liver_physiology | 2.18215211 |
17 | MP0004019_abnormal_vitamin_homeostasis | 2.15553634 |
18 | * MP0002118_abnormal_lipid_homeostasis | 2.10142327 |
19 | MP0002138_abnormal_hepatobiliary_system | 1.94096654 |
20 | MP0003868_abnormal_feces_composition | 1.87157475 |
21 | MP0005319_abnormal_enzyme/_coenzyme | 1.82257988 |
22 | MP0003123_paternal_imprinting | 1.69299743 |
23 | MP0001764_abnormal_homeostasis | 1.68722936 |
24 | MP0009697_abnormal_copulation | 1.65286825 |
25 | MP0005451_abnormal_body_composition | 1.58494669 |
26 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.58472254 |
27 | MP0003011_delayed_dark_adaptation | 1.46930158 |
28 | MP0000566_synostosis | 1.43797211 |
29 | MP0001915_intracranial_hemorrhage | 1.43539136 |
30 | MP0003656_abnormal_erythrocyte_physiolo | 1.30648728 |
31 | MP0003186_abnormal_redox_activity | 1.28503917 |
32 | MP0002089_abnormal_postnatal_growth/wei | 1.27523643 |
33 | MP0009643_abnormal_urine_homeostasis | 1.22705409 |
34 | MP0000598_abnormal_liver_morphology | 1.18054146 |
35 | MP0004272_abnormal_basement_membrane | 1.15118308 |
36 | MP0003705_abnormal_hypodermis_morpholog | 1.12964895 |
37 | MP0005647_abnormal_sex_gland | 1.10585453 |
38 | MP0009764_decreased_sensitivity_to | 1.05568698 |
39 | MP0003172_abnormal_lysosome_physiology | 1.05254682 |
40 | MP0009763_increased_sensitivity_to | 1.01991888 |
41 | MP0004264_abnormal_extraembryonic_tissu | 1.00959141 |
42 | MP0002254_reproductive_system_inflammat | 0.99372889 |
43 | MP0010368_abnormal_lymphatic_system | 0.94288604 |
44 | MP0001986_abnormal_taste_sensitivity | 0.92773006 |
45 | MP0005636_abnormal_mineral_homeostasis | 0.92735160 |
46 | MP0008469_abnormal_protein_level | 0.87966524 |
47 | * MP0009642_abnormal_blood_homeostasis | 0.86947929 |
48 | MP0006054_spinal_hemorrhage | 0.86924403 |
49 | MP0006036_abnormal_mitochondrial_physio | 0.84609477 |
50 | MP0005408_hypopigmentation | 0.84499689 |
51 | MP0003567_abnormal_fetal_cardiomyocyte | 0.83104989 |
52 | MP0005376_homeostasis/metabolism_phenot | 0.80894679 |
53 | MP0009765_abnormal_xenobiotic_induced | 0.78589482 |
54 | MP0003121_genomic_imprinting | 0.78254453 |
55 | * MP0002078_abnormal_glucose_homeostasis | 0.76680701 |
56 | MP0002876_abnormal_thyroid_physiology | 0.76206241 |
57 | MP0005084_abnormal_gallbladder_morpholo | 0.75605654 |
58 | * MP0000604_amyloidosis | 0.72825683 |
59 | MP0002971_abnormal_brown_adipose | 0.71990130 |
60 | MP0005670_abnormal_white_adipose | 0.71976424 |
61 | MP0005334_abnormal_fat_pad | 0.70135808 |
62 | MP0003690_abnormal_glial_cell | 0.69071590 |
63 | MP0009053_abnormal_anal_canal | 0.68564246 |
64 | MP0005220_abnormal_exocrine_pancreas | 0.68220781 |
65 | MP0003329_amyloid_beta_deposits | 0.67638719 |
66 | MP0004130_abnormal_muscle_cell | 0.67390679 |
67 | MP0005409_darkened_coat_color | 0.67383572 |
68 | MP0002938_white_spotting | 0.66614508 |
69 | MP0001661_extended_life_span | 0.65905703 |
70 | MP0005535_abnormal_body_temperature | 0.65825229 |
71 | MP0005266_abnormal_metabolism | 0.64635453 |
72 | MP0000639_abnormal_adrenal_gland | 0.63751077 |
73 | MP0003879_abnormal_hair_cell | 0.63424443 |
74 | MP0003315_abnormal_perineum_morphology | 0.61555795 |
75 | MP0001756_abnormal_urination | 0.59818416 |
76 | MP0006035_abnormal_mitochondrial_morpho | 0.57396680 |
77 | MP0005448_abnormal_energy_balance | 0.57029641 |
78 | MP0009384_cardiac_valve_regurgitation | 0.56818635 |
79 | MP0001324_abnormal_eye_pigmentation | 0.55685895 |
80 | MP0005464_abnormal_platelet_physiology | 0.55507794 |
81 | MP0003950_abnormal_plasma_membrane | 0.55387317 |
82 | MP0005023_abnormal_wound_healing | 0.55362407 |
83 | MP0005410_abnormal_fertilization | 0.55116184 |
84 | MP0002822_catalepsy | 0.51850352 |
85 | MP0002909_abnormal_adrenal_gland | 0.51452979 |
86 | MP0003941_abnormal_skin_development | 0.51168798 |
87 | MP0003632_abnormal_nervous_system | 0.51048215 |
88 | MP0005257_abnormal_intraocular_pressure | 0.48986270 |
89 | MP0005395_other_phenotype | 0.48701015 |
90 | MP0000920_abnormal_myelination | 0.48397402 |
91 | MP0005379_endocrine/exocrine_gland_phen | 0.48063521 |
92 | MP0003890_abnormal_embryonic-extraembry | 0.47468866 |
93 | MP0008874_decreased_physiological_sensi | 0.47149823 |
94 | MP0003718_maternal_effect | 0.46822487 |
95 | MP0005551_abnormal_eye_electrophysiolog | 0.46810618 |
96 | MP0003638_abnormal_response/metabolism_ | 0.46727687 |
97 | MP0003878_abnormal_ear_physiology | 0.46042148 |
98 | MP0005377_hearing/vestibular/ear_phenot | 0.46042148 |
99 | MP0008873_increased_physiological_sensi | 0.45847314 |
100 | MP0003943_abnormal_hepatobiliary_system | 0.45783882 |
101 | MP0002136_abnormal_kidney_physiology | 0.44673644 |
102 | MP0009780_abnormal_chondrocyte_physiolo | 0.44254467 |
103 | MP0002837_dystrophic_cardiac_calcinosis | 0.43849125 |
104 | MP0004782_abnormal_surfactant_physiolog | 0.41956397 |
105 | MP0003699_abnormal_female_reproductive | 0.41736001 |
106 | MP0002928_abnormal_bile_duct | 0.41719265 |
107 | MP0002282_abnormal_trachea_morphology | 0.41512284 |
108 | MP0003075_altered_response_to | 0.41487167 |
109 | MP0001270_distended_abdomen | 0.41352335 |
110 | MP0005248_abnormal_Harderian_gland | 0.40692935 |
111 | MP0005187_abnormal_penis_morphology | 0.40679088 |
112 | MP0003436_decreased_susceptibility_to | 0.40431785 |
113 | MP0008872_abnormal_physiological_respon | 0.39925382 |
114 | * MP0003953_abnormal_hormone_level | 0.39497116 |
115 | MP0009672_abnormal_birth_weight | 0.38068824 |
116 | MP0003724_increased_susceptibility_to | 0.37601655 |
117 | MP0005666_abnormal_adipose_tissue | 0.35971256 |
118 | MP0004883_abnormal_blood_vessel | 0.35749717 |
119 | MP0005166_decreased_susceptibility_to | 0.34504240 |
120 | MP0000249_abnormal_blood_vessel | 0.34203232 |
121 | MP0001243_abnormal_dermal_layer | 0.34172575 |
122 | MP0009115_abnormal_fat_cell | 0.33705619 |
123 | MP0006082_CNS_inflammation | 0.32833851 |
124 | MP0002796_impaired_skin_barrier | 0.31372805 |
125 | MP0000230_abnormal_systemic_arterial | 0.31173893 |
126 | MP0002168_other_aberrant_phenotype | 0.30921356 |
127 | MP0002970_abnormal_white_adipose | 0.30902705 |
128 | MP0001853_heart_inflammation | 0.30418227 |
129 | MP0004381_abnormal_hair_follicle | 0.29118113 |
130 | MP0001845_abnormal_inflammatory_respons | 0.27662309 |
131 | MP0000579_abnormal_nail_morphology | 0.27532785 |
132 | MP0001881_abnormal_mammary_gland | 0.27193137 |
133 | MP0005164_abnormal_response_to | 0.26859963 |
134 | MP0002090_abnormal_vision | 0.24997078 |
135 | MP0005167_abnormal_blood-brain_barrier | 0.23694378 |
136 | MP0002132_abnormal_respiratory_system | 0.22501510 |
137 | MP0005058_abnormal_lysosome_morphology | 0.22492774 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Deep venous thrombosis (HP:0002625) | 7.49964846 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.47151563 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.13697105 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.65664007 |
5 | Hypobetalipoproteinemia (HP:0003563) | 6.64698353 |
6 | Prolonged partial thromboplastin time (HP:0003645) | 6.57184198 |
7 | Xanthomatosis (HP:0000991) | 6.35909499 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.74963714 |
9 | Hypolipoproteinemia (HP:0010981) | 4.96817351 |
10 | Complement deficiency (HP:0004431) | 4.91295387 |
11 | Joint hemorrhage (HP:0005261) | 4.87083078 |
12 | Hyperammonemia (HP:0001987) | 4.61858788 |
13 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.53200765 |
14 | Epidermoid cyst (HP:0200040) | 4.47360757 |
15 | Abnormality of the common coagulation pathway (HP:0010990) | 4.43079723 |
16 | Hyperglycinemia (HP:0002154) | 4.39025619 |
17 | Hypoalphalipoproteinemia (HP:0003233) | 4.33963239 |
18 | Abnormality of methionine metabolism (HP:0010901) | 4.33383673 |
19 | Ketosis (HP:0001946) | 4.28406678 |
20 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.24541606 |
21 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.13184698 |
22 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.09107633 |
23 | Fat malabsorption (HP:0002630) | 4.02947196 |
24 | Hypoglycemic coma (HP:0001325) | 3.96431462 |
25 | Hyperglycinuria (HP:0003108) | 3.93065417 |
26 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.91952854 |
27 | Abnormality of glycine metabolism (HP:0010895) | 3.91952854 |
28 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.84023850 |
29 | Abnormality of the intrinsic pathway (HP:0010989) | 3.74324241 |
30 | Hypercholesterolemia (HP:0003124) | 3.70700020 |
31 | Conjugated hyperbilirubinemia (HP:0002908) | 3.61119717 |
32 | Abnormality of complement system (HP:0005339) | 3.57996655 |
33 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.39804388 |
34 | Hyperbilirubinemia (HP:0002904) | 3.39007116 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.38361595 |
36 | Delayed CNS myelination (HP:0002188) | 3.10829668 |
37 | Abnormality of serum amino acid levels (HP:0003112) | 3.05833200 |
38 | Abnormality of nucleobase metabolism (HP:0010932) | 3.04374387 |
39 | Ketoacidosis (HP:0001993) | 3.03790470 |
40 | Osteomalacia (HP:0002749) | 3.02655640 |
41 | Spontaneous abortion (HP:0005268) | 3.01029856 |
42 | Steatorrhea (HP:0002570) | 3.00806757 |
43 | Hypochromic microcytic anemia (HP:0004840) | 2.98621801 |
44 | Hepatocellular carcinoma (HP:0001402) | 2.97507141 |
45 | Myocardial infarction (HP:0001658) | 2.88711603 |
46 | Metabolic acidosis (HP:0001942) | 2.79960624 |
47 | Skin nodule (HP:0200036) | 2.75587101 |
48 | Abnormality of purine metabolism (HP:0004352) | 2.64549656 |
49 | Acanthocytosis (HP:0001927) | 2.64245200 |
50 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.63265175 |
51 | Dicarboxylic aciduria (HP:0003215) | 2.63265175 |
52 | Lethargy (HP:0001254) | 2.61702453 |
53 | Vascular calcification (HP:0004934) | 2.61117190 |
54 | Purpura (HP:0000979) | 2.56958863 |
55 | Abnormality of carpal bone ossification (HP:0006257) | 2.56499953 |
56 | Hypoglycemic seizures (HP:0002173) | 2.54701501 |
57 | Systemic lupus erythematosus (HP:0002725) | 2.52313482 |
58 | Abnormal gallbladder morphology (HP:0012437) | 2.51004399 |
59 | Spastic diplegia (HP:0001264) | 2.45664300 |
60 | Abnormal tarsal ossification (HP:0008369) | 2.45353851 |
61 | Abnormal gallbladder physiology (HP:0012438) | 2.45170664 |
62 | Cholecystitis (HP:0001082) | 2.45170664 |
63 | Cholelithiasis (HP:0001081) | 2.44816774 |
64 | Cerebral edema (HP:0002181) | 2.44036818 |
65 | Glomerulonephritis (HP:0000099) | 2.42635701 |
66 | Mitral stenosis (HP:0001718) | 2.40419979 |
67 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.39866362 |
68 | Amyloidosis (HP:0011034) | 2.39468998 |
69 | Retinal atrophy (HP:0001105) | 2.37723660 |
70 | Gout (HP:0001997) | 2.35254674 |
71 | Irritability (HP:0000737) | 2.34509231 |
72 | Malnutrition (HP:0004395) | 2.31547022 |
73 | Cardiovascular calcification (HP:0011915) | 2.31501223 |
74 | Neonatal onset (HP:0003623) | 2.29368125 |
75 | Broad alveolar ridges (HP:0000187) | 2.29068842 |
76 | Hepatoblastoma (HP:0002884) | 2.26950926 |
77 | Gingival bleeding (HP:0000225) | 2.22909374 |
78 | Esophageal varix (HP:0002040) | 2.21348673 |
79 | Menorrhagia (HP:0000132) | 2.19789807 |
80 | Late onset (HP:0003584) | 2.17427685 |
81 | Brushfield spots (HP:0001088) | 2.16894667 |
82 | Joint swelling (HP:0001386) | 2.15232536 |
83 | Increased serum pyruvate (HP:0003542) | 2.15210329 |
84 | Pancreatitis (HP:0001733) | 2.13122603 |
85 | Poikilocytosis (HP:0004447) | 2.10823071 |
86 | Arthropathy (HP:0003040) | 2.09850380 |
87 | Enlarged kidneys (HP:0000105) | 2.09610485 |
88 | Thrombophlebitis (HP:0004418) | 2.09431836 |
89 | Abnormal delivery (HP:0001787) | 2.09405944 |
90 | Vomiting (HP:0002013) | 2.08555757 |
91 | Sensorimotor neuropathy (HP:0007141) | 2.08516201 |
92 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.08492717 |
93 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.06892198 |
94 | Generalized aminoaciduria (HP:0002909) | 2.05790275 |
95 | Opisthotonus (HP:0002179) | 2.02535892 |
96 | Abnormality of the gallbladder (HP:0005264) | 2.01996787 |
97 | Hemorrhage of the eye (HP:0011885) | 2.00921185 |
98 | Diastasis recti (HP:0001540) | 1.96000932 |
99 | Epistaxis (HP:0000421) | 1.95779979 |
100 | Abnormality of the nasal septum (HP:0000419) | 1.95207246 |
101 | Abnormality of iron homeostasis (HP:0011031) | 1.94352962 |
102 | Rickets (HP:0002748) | 1.94186598 |
103 | Potter facies (HP:0002009) | 1.93078488 |
104 | Facial shape deformation (HP:0011334) | 1.93078488 |
105 | Abnormality of glycolysis (HP:0004366) | 1.92080203 |
106 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.90854349 |
107 | Abnormality of the Achilles tendon (HP:0005109) | 1.90433254 |
108 | Abnormal cartilage morphology (HP:0002763) | 1.88730209 |
109 | Abnormality of urine glucose concentration (HP:0011016) | 1.88200630 |
110 | Glycosuria (HP:0003076) | 1.88200630 |
111 | Renal cortical cysts (HP:0000803) | 1.87244917 |
112 | Hypophosphatemic rickets (HP:0004912) | 1.86821699 |
113 | Abnormality of proline metabolism (HP:0010907) | 1.86696283 |
114 | Hydroxyprolinuria (HP:0003080) | 1.86696283 |
115 | Abnormal hand bone ossification (HP:0010660) | 1.84969919 |
116 | Flat acetabular roof (HP:0003180) | 1.84396561 |
117 | Pulmonary embolism (HP:0002204) | 1.83285934 |
118 | Small epiphyses (HP:0010585) | 1.83046782 |
119 | Broad palm (HP:0001169) | 1.81909508 |
120 | Increased serum ferritin (HP:0003281) | 1.80663926 |
121 | Alkalosis (HP:0001948) | 1.80255218 |
122 | Elevated hepatic transaminases (HP:0002910) | 1.79083835 |
123 | Status epilepticus (HP:0002133) | 1.78077222 |
124 | Abnormal ossification of hand bones (HP:0005921) | 1.77980559 |
125 | Reticulocytosis (HP:0001923) | 1.77132319 |
126 | Proximal tubulopathy (HP:0000114) | 1.74571839 |
127 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.74554644 |
128 | Abnormality of vitamin metabolism (HP:0100508) | 1.74522060 |
129 | Nephritis (HP:0000123) | 1.73086110 |
130 | Bifid scrotum (HP:0000048) | 1.62859176 |
131 | Prenatal maternal abnormality (HP:0002686) | 1.61933613 |
132 | Reduced antithrombin III activity (HP:0001976) | 1.60424623 |
133 | Hyperphosphaturia (HP:0003109) | 1.59818694 |
134 | Vaginal fistula (HP:0004320) | 1.59806826 |
135 | Abnormality of the lumbar spine (HP:0100712) | 1.55682739 |
136 | Pigmentary retinal degeneration (HP:0001146) | 1.53396586 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.38402999 |
2 | PDK2 | 5.14958877 |
3 | SIK1 | 4.74134799 |
4 | FGFR4 | 4.54398178 |
5 | ERN1 | 4.20108105 |
6 | WNK4 | 3.06126639 |
7 | INSRR | 2.98599253 |
8 | TAOK3 | 2.98365849 |
9 | ERBB4 | 2.54606526 |
10 | PKN2 | 2.50230505 |
11 | AKT3 | 2.49753520 |
12 | MAP2K4 | 2.32369524 |
13 | PIK3CA | 2.31671248 |
14 | FGFR1 | 2.10658140 |
15 | FLT3 | 2.09984847 |
16 | MST1R | 2.09375664 |
17 | CDK12 | 2.04608466 |
18 | PIK3CG | 1.92231243 |
19 | PDGFRA | 1.85375950 |
20 | TYRO3 | 1.84973451 |
21 | TRIB3 | 1.82387367 |
22 | MAPK11 | 1.77779309 |
23 | TYK2 | 1.70290624 |
24 | DAPK2 | 1.67883780 |
25 | LATS1 | 1.56787148 |
26 | ABL2 | 1.50675961 |
27 | PTK6 | 1.47484064 |
28 | KDR | 1.41608371 |
29 | NEK9 | 1.36352935 |
30 | FGFR2 | 1.33231457 |
31 | NTRK3 | 1.31128555 |
32 | MAP3K2 | 1.30252052 |
33 | FRK | 1.28352553 |
34 | JAK2 | 1.19379369 |
35 | ACVR1B | 1.18865665 |
36 | WNK1 | 1.17171384 |
37 | PINK1 | 1.16608972 |
38 | NEK1 | 1.14528741 |
39 | LMTK2 | 1.14235879 |
40 | MAP2K3 | 1.13061337 |
41 | MAP3K7 | 1.12783928 |
42 | PRKAA2 | 1.12149510 |
43 | GRK6 | 1.09980225 |
44 | TBK1 | 1.05799625 |
45 | MAPK4 | 0.98933722 |
46 | JAK1 | 0.97621496 |
47 | MAP3K10 | 0.97110210 |
48 | MAP3K14 | 0.94226396 |
49 | PRKCZ | 0.92109707 |
50 | MAP3K3 | 0.92043064 |
51 | ERBB2 | 0.90152624 |
52 | MAP3K11 | 0.88808570 |
53 | MET | 0.85699701 |
54 | CSNK1E | 0.84650944 |
55 | CDK6 | 0.82473990 |
56 | RPS6KB1 | 0.82027965 |
57 | STK38L | 0.81711337 |
58 | MAPK12 | 0.81557423 |
59 | MAPK15 | 0.80984037 |
60 | TIE1 | 0.80465621 |
61 | EPHB1 | 0.79533920 |
62 | CDK7 | 0.78757776 |
63 | PRKACG | 0.77586124 |
64 | EIF2AK1 | 0.77070988 |
65 | NLK | 0.76002525 |
66 | DYRK1B | 0.74573295 |
67 | CSK | 0.74537056 |
68 | TESK2 | 0.74463745 |
69 | CAMK1D | 0.73080951 |
70 | BCR | 0.71053435 |
71 | MAP2K6 | 0.70516139 |
72 | CSNK1D | 0.68876930 |
73 | SIK2 | 0.68545987 |
74 | GSK3A | 0.68149170 |
75 | CAMK2G | 0.67848739 |
76 | MUSK | 0.67830885 |
77 | FGR | 0.67361957 |
78 | STK39 | 0.66143352 |
79 | EPHA3 | 0.65344782 |
80 | PRKAA1 | 0.63750517 |
81 | TGFBR2 | 0.61532416 |
82 | SGK1 | 0.60889072 |
83 | RIPK1 | 0.59890046 |
84 | CSNK2A2 | 0.59841960 |
85 | DDR2 | 0.59585971 |
86 | PTK2 | 0.59045119 |
87 | SGK3 | 0.58662145 |
88 | CSF1R | 0.57154667 |
89 | MAPK7 | 0.55689169 |
90 | PRKG1 | 0.55468224 |
91 | IRAK3 | 0.54438622 |
92 | TAOK2 | 0.54348150 |
93 | EPHA4 | 0.54185137 |
94 | PRKACB | 0.52992241 |
95 | PDPK1 | 0.52483471 |
96 | PRKCQ | 0.52420913 |
97 | IKBKE | 0.52280520 |
98 | CSNK2A1 | 0.52239511 |
99 | CSNK1G1 | 0.51961939 |
100 | FGFR3 | 0.50127008 |
101 | MAPKAPK3 | 0.47838844 |
102 | WNK3 | 0.47397836 |
103 | MAP3K12 | 0.46805951 |
104 | GRK1 | 0.45440280 |
105 | EIF2AK3 | 0.45436456 |
106 | MAP2K1 | 0.45341353 |
107 | BRSK1 | 0.44784092 |
108 | MAP3K5 | 0.44537164 |
109 | CDK4 | 0.43567656 |
110 | IGF1R | 0.43122921 |
111 | RET | 0.42603320 |
112 | BRSK2 | 0.42213326 |
113 | PRKCG | 0.42013218 |
114 | PRKCB | 0.41656918 |
115 | MAP3K13 | 0.40695795 |
116 | PBK | 0.40580431 |
117 | SGK2 | 0.40379196 |
118 | MAP3K6 | 0.38128621 |
119 | CDC42BPA | 0.37715208 |
120 | ICK | 0.36670455 |
121 | MELK | 0.35792718 |
122 | SRC | 0.35475963 |
123 | STK16 | 0.35308742 |
124 | TRIM28 | 0.35056671 |
125 | SCYL2 | 0.34886074 |
126 | EEF2K | 0.34826354 |
127 | MTOR | 0.34823866 |
128 | PDK1 | 0.34278688 |
129 | CAMK4 | 0.33652437 |
130 | RPS6KA3 | 0.33273384 |
131 | CSNK1G2 | 0.32643928 |
132 | MATK | 0.32560624 |
133 | EGFR | 0.31071927 |
134 | CSNK1G3 | 0.30887087 |
135 | PRKACA | 0.30669897 |
136 | NEK2 | 0.30558867 |
137 | SGK223 | 0.30181695 |
138 | SGK494 | 0.30181695 |
139 | MAPK10 | 0.27992279 |
140 | MAP3K1 | 0.27051984 |
141 | EPHA2 | 0.27000821 |
142 | PRKCA | 0.26063857 |
143 | MAP2K2 | 0.25645559 |
144 | LATS2 | 0.25445201 |
145 | PKN1 | 0.23849604 |
146 | CAMK1G | 0.21665805 |
147 | PAK3 | 0.21203028 |
148 | PDK3 | 0.21183027 |
149 | PDK4 | 0.21183027 |
150 | CSNK1A1L | 0.20643102 |
151 | BMX | 0.19609610 |
152 | IRAK2 | 0.19471051 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.40575247 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.56987822 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.42354555 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.33784092 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.05764818 |
6 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.79780046 |
7 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.70632753 |
8 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.66719709 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.63663201 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.53707700 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.50793823 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.39309956 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.29003059 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.17765542 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.17571790 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.07333478 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.00432631 |
18 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.98631891 |
19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.94676751 |
20 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.93045847 |
21 | Histidine metabolism_Homo sapiens_hsa00340 | 1.91369066 |
22 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.84292795 |
23 | * PPAR signaling pathway_Homo sapiens_hsa03320 | 1.79993160 |
24 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.79081458 |
25 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.73671786 |
26 | Retinol metabolism_Homo sapiens_hsa00830 | 1.73400672 |
27 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.73288187 |
28 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.72620977 |
29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.70849693 |
30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.67942414 |
31 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.65780374 |
32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.57383384 |
33 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.54971823 |
34 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50898962 |
35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.50690569 |
36 | Bile secretion_Homo sapiens_hsa04976 | 1.47966769 |
37 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.42397343 |
38 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.38851096 |
39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.38291848 |
40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.35240548 |
41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.31926361 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.28058490 |
43 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21778616 |
44 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.21611229 |
45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.20531256 |
46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.20503248 |
47 | ABC transporters_Homo sapiens_hsa02010 | 1.18220661 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 1.14092989 |
49 | Other glycan degradation_Homo sapiens_hsa00511 | 1.05153161 |
50 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.02693539 |
51 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.00987569 |
52 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.00455073 |
53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.99315754 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.98876293 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.95659699 |
56 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.89234947 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.87185447 |
58 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.85707822 |
59 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82854688 |
60 | Lysine degradation_Homo sapiens_hsa00310 | 0.81596254 |
61 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.77032879 |
62 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71496461 |
63 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.68494283 |
64 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66464380 |
65 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.59718910 |
66 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.55058990 |
67 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.47643611 |
68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46175621 |
69 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43459907 |
70 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.41160123 |
71 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.32661252 |
72 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.27080780 |
73 | Prion diseases_Homo sapiens_hsa05020 | 0.26727436 |
74 | Galactose metabolism_Homo sapiens_hsa00052 | 0.26573320 |
75 | Pertussis_Homo sapiens_hsa05133 | 0.26432941 |
76 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.25022200 |
77 | Mineral absorption_Homo sapiens_hsa04978 | 0.24391494 |
78 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.24155598 |
79 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.22354991 |
80 | Insulin resistance_Homo sapiens_hsa04931 | 0.22099390 |
81 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.20673079 |
82 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.15591708 |
83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.08959647 |
84 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.03196158 |
85 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01301250 |
86 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.01287825 |
87 | Bladder cancer_Homo sapiens_hsa05219 | -0.2561330 |
88 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2467568 |
89 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2424313 |
90 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2376454 |
91 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2362642 |
92 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.2080469 |
93 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1991144 |
94 | Hepatitis C_Homo sapiens_hsa05160 | -0.1945658 |
95 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.1889579 |
96 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1813351 |
97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1714109 |
98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1657968 |
99 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1622626 |
100 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1586802 |
101 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1556472 |
102 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1312036 |
103 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | -0.1073633 |
104 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.1045491 |
105 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1024133 |
106 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0699640 |
107 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0696637 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0262897 |
109 | ECM-receptor interaction_Homo sapiens_hsa04512 | -0.0019511 |