Rank | Gene Set | Z-score |
---|---|---|
1 | actin-mediated cell contraction (GO:0070252) | 9.11795458 |
2 | regulation of skeletal muscle contraction (GO:0014819) | 9.05979897 |
3 | sarcomere organization (GO:0045214) | 8.93143486 |
4 | myofibril assembly (GO:0030239) | 8.01043484 |
5 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 7.78834581 |
6 | cardiac myofibril assembly (GO:0055003) | 7.72396718 |
7 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 7.40252950 |
8 | plasma membrane repair (GO:0001778) | 7.36489631 |
9 | skeletal muscle contraction (GO:0003009) | 6.95588341 |
10 | actin filament-based movement (GO:0030048) | 6.79135847 |
11 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 6.67783665 |
12 | striated muscle contraction (GO:0006941) | 6.63280172 |
13 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 6.59171355 |
14 | cardiac muscle contraction (GO:0060048) | 6.50231505 |
15 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 6.27267140 |
16 | tricarboxylic acid cycle (GO:0006099) | 6.01388246 |
17 | actomyosin structure organization (GO:0031032) | 5.99132102 |
18 | regulation of relaxation of muscle (GO:1901077) | 5.86142364 |
19 | cardiac muscle cell development (GO:0055013) | 5.85331770 |
20 | cardiac cell development (GO:0055006) | 5.49967640 |
21 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 5.44576993 |
22 | heart contraction (GO:0060047) | 5.37276479 |
23 | heart process (GO:0003015) | 5.37276479 |
24 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 5.36247320 |
25 | skeletal muscle adaptation (GO:0043501) | 5.34437866 |
26 | carnitine shuttle (GO:0006853) | 5.29909170 |
27 | regulation of cell communication by electrical coupling (GO:0010649) | 5.28306103 |
28 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 5.24895502 |
29 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 5.22249526 |
30 | cardiac muscle tissue morphogenesis (GO:0055008) | 5.21833495 |
31 | regulation of actin filament-based movement (GO:1903115) | 5.20456180 |
32 | cardiac muscle hypertrophy (GO:0003300) | 5.04669739 |
33 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.93365048 |
34 | regulation of sarcomere organization (GO:0060297) | 4.93278540 |
35 | striated muscle hypertrophy (GO:0014897) | 4.91770089 |
36 | muscle tissue morphogenesis (GO:0060415) | 4.85407498 |
37 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.83452696 |
38 | adult heart development (GO:0007512) | 4.81424931 |
39 | muscle contraction (GO:0006936) | 4.74844277 |
40 | ventricular cardiac muscle cell action potential (GO:0086005) | 4.68262707 |
41 | regulation of striated muscle contraction (GO:0006942) | 4.66695616 |
42 | creatine metabolic process (GO:0006600) | 4.65652035 |
43 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.60933284 |
44 | skeletal muscle tissue development (GO:0007519) | 4.58740381 |
45 | regulation of coenzyme metabolic process (GO:0051196) | 4.54493444 |
46 | regulation of cofactor metabolic process (GO:0051193) | 4.54493444 |
47 | fatty acid transmembrane transport (GO:1902001) | 4.50707177 |
48 | heart trabecula formation (GO:0060347) | 4.46906753 |
49 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 4.38532193 |
50 | response to inactivity (GO:0014854) | 4.36098774 |
51 | muscle hypertrophy (GO:0014896) | 4.34487336 |
52 | oxidative phosphorylation (GO:0006119) | 4.33979619 |
53 | muscle system process (GO:0003012) | 4.32859150 |
54 | ATP synthesis coupled proton transport (GO:0015986) | 4.31531507 |
55 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.31531507 |
56 | striated muscle adaptation (GO:0014888) | 4.26751075 |
57 | regulation of membrane repolarization (GO:0060306) | 4.26300846 |
58 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.21734081 |
59 | striated muscle cell development (GO:0055002) | 4.19503532 |
60 | response to muscle activity (GO:0014850) | 4.15296312 |
61 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.09511214 |
62 | respiratory electron transport chain (GO:0022904) | 3.99919276 |
63 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.99164316 |
64 | negative regulation of protein localization to cell surface (GO:2000009) | 3.98999480 |
65 | muscle fiber development (GO:0048747) | 3.97492627 |
66 | skeletal muscle fiber development (GO:0048741) | 3.94755643 |
67 | glycogen catabolic process (GO:0005980) | 3.93867518 |
68 | muscle organ development (GO:0007517) | 3.92768057 |
69 | muscle structure development (GO:0061061) | 3.92743609 |
70 | muscle cell fate commitment (GO:0042693) | 3.92567249 |
71 | electron transport chain (GO:0022900) | 3.88262378 |
72 | carnitine transmembrane transport (GO:1902603) | 3.87998661 |
73 | cardiac muscle adaptation (GO:0014887) | 3.80024374 |
74 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.80024374 |
75 | muscle hypertrophy in response to stress (GO:0003299) | 3.80024374 |
76 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.80020786 |
77 | regulation of the force of heart contraction (GO:0002026) | 3.77939545 |
78 | positive regulation of myotube differentiation (GO:0010831) | 3.77596295 |
79 | skeletal muscle tissue regeneration (GO:0043403) | 3.72606425 |
80 | striated muscle atrophy (GO:0014891) | 3.67772541 |
81 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.67680961 |
82 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.67680961 |
83 | glucan catabolic process (GO:0009251) | 3.67069957 |
84 | regulation of ATP catabolic process (GO:1903289) | 3.66573438 |
85 | regulation of ATPase activity (GO:0043462) | 3.66573438 |
86 | negative regulation of muscle hypertrophy (GO:0014741) | 3.64429186 |
87 | glycogen metabolic process (GO:0005977) | 3.62715784 |
88 | regulation of sulfur metabolic process (GO:0042762) | 3.62000219 |
89 | muscle cell development (GO:0055001) | 3.59818696 |
90 | glycogen biosynthetic process (GO:0005978) | 3.55610169 |
91 | glucan biosynthetic process (GO:0009250) | 3.55610169 |
92 | negative regulation of potassium ion transport (GO:0043267) | 3.55329434 |
93 | cellular glucan metabolic process (GO:0006073) | 3.55194127 |
94 | glucan metabolic process (GO:0044042) | 3.55194127 |
95 | muscle adaptation (GO:0043500) | 3.53989012 |
96 | amino-acid betaine transport (GO:0015838) | 3.53029613 |
97 | carnitine transport (GO:0015879) | 3.53029613 |
98 | NADH metabolic process (GO:0006734) | 3.52460931 |
99 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.51306721 |
100 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.50549856 |
101 | muscle atrophy (GO:0014889) | 3.49634338 |
102 | cardiac muscle cell action potential (GO:0086001) | 3.49216004 |
103 | response to activity (GO:0014823) | 3.47485454 |
104 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.46567921 |
105 | muscle cell cellular homeostasis (GO:0046716) | 3.45557791 |
106 | cellular polysaccharide catabolic process (GO:0044247) | 3.44458431 |
107 | regulation of myoblast differentiation (GO:0045661) | 3.43029322 |
108 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.42445305 |
109 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.42445305 |
110 | regulation of muscle system process (GO:0090257) | 3.40929170 |
111 | myoblast fusion (GO:0007520) | 3.40557438 |
112 | regulation of muscle contraction (GO:0006937) | 3.39540119 |
113 | positive regulation of cation channel activity (GO:2001259) | 3.39199150 |
114 | gluconeogenesis (GO:0006094) | 3.38009084 |
115 | myotube cell development (GO:0014904) | 3.37852107 |
116 | relaxation of muscle (GO:0090075) | 3.37640457 |
117 | positive regulation of myoblast differentiation (GO:0045663) | 3.36090776 |
118 | 2-oxoglutarate metabolic process (GO:0006103) | 3.33322339 |
119 | polysaccharide catabolic process (GO:0000272) | 3.32107413 |
120 | striated muscle tissue development (GO:0014706) | 3.31870650 |
121 | muscle organ morphogenesis (GO:0048644) | 3.27826796 |
122 | fructose metabolic process (GO:0006000) | 3.27341182 |
123 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.27235639 |
124 | actin-myosin filament sliding (GO:0033275) | 11.0549623 |
125 | muscle filament sliding (GO:0030049) | 11.0549623 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 6.78563813 |
2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.54172295 |
3 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.09762478 |
4 | * ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 4.66006592 |
5 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 4.15012872 |
6 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 4.12600895 |
7 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 3.92177112 |
8 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 3.92177112 |
9 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.58702008 |
10 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 3.38073891 |
11 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.25384545 |
12 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 3.21201334 |
13 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.12964282 |
14 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.80571900 |
15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.64114991 |
16 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 2.37054856 |
17 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.28804824 |
18 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 2.05666105 |
19 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.91214197 |
20 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.90455957 |
21 | * NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.84782439 |
22 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.83973087 |
23 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.79340570 |
24 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.74450003 |
25 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.67244103 |
26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.66668830 |
27 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.64923985 |
28 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.64272162 |
29 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.62792682 |
30 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.60986551 |
31 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.57794868 |
32 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.57451170 |
33 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.55049626 |
34 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.53568467 |
35 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.52563972 |
36 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.51531948 |
37 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.49098211 |
38 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.46713842 |
39 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.35561684 |
40 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.34608758 |
41 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.33607348 |
42 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.32626846 |
43 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.27455639 |
44 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.25075716 |
45 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.24096731 |
46 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.23246017 |
47 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.22409302 |
48 | ATF3_27146783_Chip-Seq_COLON_Human | 1.20726760 |
49 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.20074257 |
50 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.19953283 |
51 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.19932937 |
52 | * TP63_22573176_ChIP-Seq_HFKS_Human | 1.19708926 |
53 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.19545332 |
54 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.19098888 |
55 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.18030780 |
56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17339107 |
57 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.16968906 |
58 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.16769818 |
59 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.16754397 |
60 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.16717299 |
61 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.16668974 |
62 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.15670648 |
63 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.15221552 |
64 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.13030656 |
65 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.12687508 |
66 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.12259419 |
67 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.11210441 |
68 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.10341472 |
69 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.10229252 |
70 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.10034917 |
71 | P68_20966046_ChIP-Seq_HELA_Human | 1.09957854 |
72 | CTCF_21964334_Chip-Seq_Bcells_Human | 1.09856264 |
73 | GATA1_22025678_ChIP-Seq_K562_Human | 1.08809525 |
74 | * OCT4_20526341_ChIP-Seq_ESCs_Human | 1.08058532 |
75 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.07367762 |
76 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.06148035 |
77 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.05939749 |
78 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.05758830 |
79 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.05710654 |
80 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.05569909 |
81 | * LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03663847 |
82 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.03471575 |
83 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.02394447 |
84 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.02237108 |
85 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.02037695 |
86 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.01919369 |
87 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.01743241 |
88 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.01228744 |
89 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.00830864 |
90 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.99826486 |
91 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.99704229 |
92 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.99669908 |
93 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.98698215 |
94 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.98455463 |
95 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.97335808 |
96 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.95779228 |
97 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.95722441 |
98 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.94707454 |
99 | SA1_27219007_Chip-Seq_Bcells_Human | 0.94393617 |
100 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.94320215 |
101 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.93521168 |
102 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.93178632 |
103 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93150420 |
104 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.93148755 |
105 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.92051513 |
106 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91913781 |
107 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.91904823 |
108 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91088122 |
109 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.90122069 |
110 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.89976227 |
111 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.89976227 |
112 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.88982125 |
113 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88553025 |
114 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.88458445 |
115 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.88210364 |
116 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.88051381 |
117 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.87897967 |
118 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.87838789 |
119 | CJUN_26792858_Chip-Seq_BT549_Human | 0.87726511 |
120 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.85495479 |
121 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.85100876 |
122 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.84746540 |
123 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.84251662 |
124 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.84056583 |
125 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.83956629 |
126 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.81823086 |
127 | * NANOG_19829295_ChIP-Seq_ESCs_Human | 0.81749703 |
128 | * SOX2_19829295_ChIP-Seq_ESCs_Human | 0.81749703 |
129 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.81450346 |
130 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.81123725 |
131 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.80055484 |
132 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.79998650 |
133 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.79703896 |
134 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.79703896 |
135 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.79394712 |
136 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.78669240 |
137 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.78248380 |
138 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.77475881 |
139 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.77225819 |
140 | VDR_22108803_ChIP-Seq_LS180_Human | 0.76100015 |
141 | GATA1_19941826_ChIP-Seq_K562_Human | 0.75711800 |
142 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.75706285 |
143 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.75009470 |
144 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.74718875 |
145 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.74718875 |
146 | PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 0.74281936 |
147 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.73902417 |
148 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.73644344 |
149 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.73596058 |
150 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.73508735 |
151 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.73468477 |
152 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.71998139 |
153 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.71355421 |
154 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.70821508 |
155 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.69804298 |
156 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.68224911 |
157 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.68174360 |
158 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.68024610 |
159 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.67450540 |
160 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.66200097 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 5.93493919 |
2 | MP0000751_myopathy | 5.56116017 |
3 | MP0000749_muscle_degeneration | 5.52211833 |
4 | MP0002837_dystrophic_cardiac_calcinosis | 5.48615482 |
5 | MP0004084_abnormal_cardiac_muscle | 4.77702571 |
6 | MP0004145_abnormal_muscle_electrophysio | 4.64272223 |
7 | MP0004036_abnormal_muscle_relaxation | 4.56442443 |
8 | MP0004215_abnormal_myocardial_fiber | 3.59740666 |
9 | MP0005330_cardiomyopathy | 3.50319722 |
10 | MP0004087_abnormal_muscle_fiber | 3.46261937 |
11 | MP0002106_abnormal_muscle_physiology | 3.38580359 |
12 | MP0000747_muscle_weakness | 3.21998061 |
13 | MP0005620_abnormal_muscle_contractility | 3.13924879 |
14 | MP0000750_abnormal_muscle_regeneration | 3.08906914 |
15 | MP0002269_muscular_atrophy | 2.93614922 |
16 | MP0000759_abnormal_skeletal_muscle | 2.83398842 |
17 | MP0002972_abnormal_cardiac_muscle | 2.76503949 |
18 | MP0005369_muscle_phenotype | 2.75220160 |
19 | MP0004130_abnormal_muscle_cell | 2.70412059 |
20 | MP0010630_abnormal_cardiac_muscle | 2.29983328 |
21 | MP0008775_abnormal_heart_ventricle | 2.24414793 |
22 | MP0004484_altered_response_of | 2.21222099 |
23 | MP0003137_abnormal_impulse_conducting | 2.20011001 |
24 | MP0001544_abnormal_cardiovascular_syste | 2.14984066 |
25 | MP0005385_cardiovascular_system_phenoty | 2.14984066 |
26 | MP0004233_abnormal_muscle_weight | 2.11439889 |
27 | MP0006036_abnormal_mitochondrial_physio | 1.97512066 |
28 | MP0002332_abnormal_exercise_endurance | 1.92746287 |
29 | MP0003221_abnormal_cardiomyocyte_apopto | 1.92587482 |
30 | MP0006138_congestive_heart_failure | 1.82410374 |
31 | MP0003950_abnormal_plasma_membrane | 1.82002781 |
32 | MP0003828_pulmonary_edema | 1.65069368 |
33 | MP0004085_abnormal_heartbeat | 1.51656887 |
34 | MP0002127_abnormal_cardiovascular_syste | 1.51306789 |
35 | MP0004510_myositis | 1.40811046 |
36 | MP0000733_abnormal_muscle_development | 1.40480467 |
37 | MP0005666_abnormal_adipose_tissue | 1.34714511 |
38 | MP0002108_abnormal_muscle_morphology | 1.27249840 |
39 | MP0004185_abnormal_adipocyte_glucose | 1.26991963 |
40 | MP0002234_abnormal_pharynx_morphology | 1.13214310 |
41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12585416 |
42 | MP0001661_extended_life_span | 1.06633234 |
43 | MP0006035_abnormal_mitochondrial_morpho | 1.06613568 |
44 | MP0002822_catalepsy | 1.06257150 |
45 | MP0000266_abnormal_heart_morphology | 1.01337872 |
46 | MP0003806_abnormal_nucleotide_metabolis | 1.01332487 |
47 | MP0005275_abnormal_skin_tensile | 0.99506640 |
48 | MP0005266_abnormal_metabolism | 0.99080117 |
49 | MP0000343_altered_response_to | 0.98202485 |
50 | MP0003705_abnormal_hypodermis_morpholog | 0.96136089 |
51 | MP0005375_adipose_tissue_phenotype | 0.91027031 |
52 | MP0002971_abnormal_brown_adipose | 0.85194170 |
53 | MP0005451_abnormal_body_composition | 0.82632493 |
54 | MP0005670_abnormal_white_adipose | 0.77965328 |
55 | MP0009780_abnormal_chondrocyte_physiolo | 0.74933991 |
56 | MP0005165_increased_susceptibility_to | 0.67325036 |
57 | MP0000372_irregular_coat_pigmentation | 0.66737059 |
58 | MP0003566_abnormal_cell_adhesion | 0.63964834 |
59 | MP0000230_abnormal_systemic_arterial | 0.63140124 |
60 | MP0004043_abnormal_pH_regulation | 0.63090405 |
61 | MP0002128_abnormal_blood_circulation | 0.58790243 |
62 | MP0000013_abnormal_adipose_tissue | 0.58427767 |
63 | MP0002638_abnormal_pupillary_reflex | 0.56885150 |
64 | MP0003279_aneurysm | 0.54906331 |
65 | MP0000762_abnormal_tongue_morphology | 0.52726107 |
66 | MP0004134_abnormal_chest_morphology | 0.50243942 |
67 | MP0003879_abnormal_hair_cell | 0.49205219 |
68 | MP0000579_abnormal_nail_morphology | 0.49189737 |
69 | MP0004147_increased_porphyrin_level | 0.47412388 |
70 | MP0000003_abnormal_adipose_tissue | 0.46207908 |
71 | MP0002796_impaired_skin_barrier | 0.45425598 |
72 | MP0002078_abnormal_glucose_homeostasis | 0.42294986 |
73 | MP0010368_abnormal_lymphatic_system | 0.41808719 |
74 | MP0005319_abnormal_enzyme/_coenzyme | 0.40608600 |
75 | MP0005167_abnormal_blood-brain_barrier | 0.38354130 |
76 | MP0000767_abnormal_smooth_muscle | 0.38255633 |
77 | MP0008961_abnormal_basal_metabolism | 0.38188634 |
78 | MP0004142_abnormal_muscle_tone | 0.36981894 |
79 | MP0002925_abnormal_cardiovascular_devel | 0.36930481 |
80 | MP0004272_abnormal_basement_membrane | 0.35070367 |
81 | MP0008438_abnormal_cutaneous_collagen | 0.34638110 |
82 | MP0001879_abnormal_lymphatic_vessel | 0.34386295 |
83 | MP0001784_abnormal_fluid_regulation | 0.34316209 |
84 | MP0006276_abnormal_autonomic_nervous | 0.33864176 |
85 | MP0003948_abnormal_gas_homeostasis | 0.30656238 |
86 | MP0002734_abnormal_mechanical_nocicepti | 0.30419268 |
87 | MP0002114_abnormal_axial_skeleton | 0.30063569 |
88 | MP0003941_abnormal_skin_development | 0.29936753 |
89 | MP0002909_abnormal_adrenal_gland | 0.29055586 |
90 | MP0001614_abnormal_blood_vessel | 0.27242514 |
91 | MP0003984_embryonic_growth_retardation | 0.27089331 |
92 | MP0005083_abnormal_biliary_tract | 0.27071081 |
93 | MP0002088_abnormal_embryonic_growth/wei | 0.26810315 |
94 | MP0005645_abnormal_hypothalamus_physiol | 0.26790421 |
95 | MP0005334_abnormal_fat_pad | 0.26772868 |
96 | MP0010030_abnormal_orbit_morphology | 0.26585585 |
97 | MP0005623_abnormal_meninges_morphology | 0.26052075 |
98 | MP0005332_abnormal_amino_acid | 0.25655628 |
99 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.25522449 |
100 | MP0005452_abnormal_adipose_tissue | 0.25136710 |
101 | MP0005166_decreased_susceptibility_to | 0.24074374 |
102 | MP0005187_abnormal_penis_morphology | 0.23507961 |
103 | MP0009672_abnormal_birth_weight | 0.22334896 |
104 | MP0004924_abnormal_behavior | 0.21059711 |
105 | MP0005386_behavior/neurological_phenoty | 0.21059711 |
106 | MP0005376_homeostasis/metabolism_phenot | 0.20736782 |
107 | MP0001943_abnormal_respiration | 0.20708409 |
108 | MP0001299_abnormal_eye_distance/ | 0.20626348 |
109 | MP0005423_abnormal_somatic_nervous | 0.20478774 |
110 | MP0009384_cardiac_valve_regurgitation | 0.20320008 |
111 | MP0002066_abnormal_motor_capabilities/c | 0.20298616 |
112 | MP0003656_abnormal_erythrocyte_physiolo | 0.18332602 |
113 | MP0004270_analgesia | 0.17778090 |
114 | MP0005535_abnormal_body_temperature | 0.17546642 |
115 | MP0009250_abnormal_appendicular_skeleto | 0.17280899 |
116 | MP0003385_abnormal_body_wall | 0.16735040 |
117 | MP0001727_abnormal_embryo_implantation | 0.16674082 |
118 | MP0009115_abnormal_fat_cell | 0.16375504 |
119 | MP0002876_abnormal_thyroid_physiology | 0.15060099 |
120 | MP0003045_fibrosis | 0.15013549 |
121 | MP0001346_abnormal_lacrimal_gland | 0.14837831 |
122 | MP0008569_lethality_at_weaning | 0.14776303 |
123 | MP0001984_abnormal_olfaction | 0.14279803 |
124 | MP0002067_abnormal_sensory_capabilities | 0.14069091 |
125 | MP0005501_abnormal_skin_physiology | 0.13732257 |
126 | MP0001853_heart_inflammation | 0.12893240 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Exercise-induced myalgia (HP:0003738) | 7.92585530 |
2 | Exercise-induced muscle cramps (HP:0003710) | 7.61885765 |
3 | Muscle fiber inclusion bodies (HP:0100299) | 7.49569439 |
4 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 7.19142649 |
5 | Muscle hypertrophy of the lower extremities (HP:0008968) | 6.80914152 |
6 | Calf muscle hypertrophy (HP:0008981) | 6.78384158 |
7 | Nemaline bodies (HP:0003798) | 6.70070388 |
8 | Type 1 muscle fiber predominance (HP:0003803) | 6.15136040 |
9 | Sudden death (HP:0001699) | 5.87150061 |
10 | Muscle fiber splitting (HP:0003555) | 5.75292162 |
11 | Myoglobinuria (HP:0002913) | 5.40278899 |
12 | Hyporeflexia of lower limbs (HP:0002600) | 5.38708428 |
13 | Abnormality of the calf musculature (HP:0001430) | 5.17914294 |
14 | Distal arthrogryposis (HP:0005684) | 4.96781310 |
15 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.89195993 |
16 | Subaortic stenosis (HP:0001682) | 4.89195993 |
17 | Ventricular tachycardia (HP:0004756) | 4.88295550 |
18 | EMG: myopathic abnormalities (HP:0003458) | 4.85276825 |
19 | Difficulty running (HP:0009046) | 4.52744611 |
20 | Myopathic facies (HP:0002058) | 4.46122686 |
21 | Rhabdomyolysis (HP:0003201) | 4.39900543 |
22 | Increased connective tissue (HP:0009025) | 4.33872506 |
23 | Round ear (HP:0100830) | 4.17564826 |
24 | Asymmetric septal hypertrophy (HP:0001670) | 3.84943375 |
25 | Lipoatrophy (HP:0100578) | 3.84416866 |
26 | Muscle stiffness (HP:0003552) | 3.84274649 |
27 | Myotonia (HP:0002486) | 3.83231837 |
28 | Ulnar deviation of the wrist (HP:0003049) | 3.79057163 |
29 | Atrial fibrillation (HP:0005110) | 3.74849075 |
30 | Neck muscle weakness (HP:0000467) | 3.58433283 |
31 | Primary atrial arrhythmia (HP:0001692) | 3.49003086 |
32 | Right ventricular cardiomyopathy (HP:0011663) | 3.43191250 |
33 | Abnormality of skeletal muscle fiber size (HP:0012084) | 3.41712630 |
34 | Supraventricular tachycardia (HP:0004755) | 3.37960032 |
35 | Dilated cardiomyopathy (HP:0001644) | 3.33686992 |
36 | Supraventricular arrhythmia (HP:0005115) | 3.30520296 |
37 | Rimmed vacuoles (HP:0003805) | 3.20445777 |
38 | Difficulty climbing stairs (HP:0003551) | 3.16613064 |
39 | Increased variability in muscle fiber diameter (HP:0003557) | 3.14318619 |
40 | Calcaneovalgus deformity (HP:0001848) | 3.14132861 |
41 | Areflexia of lower limbs (HP:0002522) | 3.13040432 |
42 | Palpitations (HP:0001962) | 3.00480343 |
43 | Distal lower limb muscle weakness (HP:0009053) | 2.99750821 |
44 | Bundle branch block (HP:0011710) | 2.99466475 |
45 | Absent phalangeal crease (HP:0006109) | 2.92092322 |
46 | Ventricular arrhythmia (HP:0004308) | 2.91826116 |
47 | Fetal akinesia sequence (HP:0001989) | 2.89769516 |
48 | Prolonged QT interval (HP:0001657) | 2.87511870 |
49 | Syncope (HP:0001279) | 2.84905359 |
50 | Deformed tarsal bones (HP:0008119) | 2.79334052 |
51 | Frequent falls (HP:0002359) | 2.66193686 |
52 | EMG: neuropathic changes (HP:0003445) | 2.56300251 |
53 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.48634453 |
54 | Heart block (HP:0012722) | 2.47911196 |
55 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.44624038 |
56 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.43285745 |
57 | Generalized muscle weakness (HP:0003324) | 2.42743227 |
58 | Acute necrotizing encephalopathy (HP:0006965) | 2.38908736 |
59 | Abnormal finger flexion creases (HP:0006143) | 2.37394927 |
60 | Abnormal atrioventricular conduction (HP:0005150) | 2.35153806 |
61 | Hyperkalemia (HP:0002153) | 2.31003992 |
62 | Ventricular fibrillation (HP:0001663) | 2.27214436 |
63 | Muscular dystrophy (HP:0003560) | 2.24398742 |
64 | Limb-girdle muscle atrophy (HP:0003797) | 2.21554768 |
65 | Conjunctival hamartoma (HP:0100780) | 2.19934053 |
66 | Exercise intolerance (HP:0003546) | 2.19768223 |
67 | Facial diplegia (HP:0001349) | 2.18768325 |
68 | Left ventricular hypertrophy (HP:0001712) | 2.17943704 |
69 | Popliteal pterygium (HP:0009756) | 2.17718331 |
70 | Hepatic necrosis (HP:0002605) | 2.17671812 |
71 | Scapular winging (HP:0003691) | 2.17281513 |
72 | Gowers sign (HP:0003391) | 2.16881206 |
73 | Malignant hyperthermia (HP:0002047) | 2.13250156 |
74 | Atrioventricular block (HP:0001678) | 2.09784720 |
75 | Progressive muscle weakness (HP:0003323) | 2.09699745 |
76 | Abnormal EKG (HP:0003115) | 2.09011604 |
77 | Palmoplantar keratoderma (HP:0000982) | 2.08670019 |
78 | Spinal rigidity (HP:0003306) | 2.08626299 |
79 | Distal lower limb amyotrophy (HP:0008944) | 2.03094809 |
80 | Acute encephalopathy (HP:0006846) | 2.01957131 |
81 | Hypoplastic ischia (HP:0003175) | 2.00916369 |
82 | Proximal amyotrophy (HP:0007126) | 1.99090501 |
83 | Waddling gait (HP:0002515) | 1.95179196 |
84 | Progressive macrocephaly (HP:0004481) | 1.95000524 |
85 | Ragged-red muscle fibers (HP:0003200) | 1.94688503 |
86 | Abnormality of the foot musculature (HP:0001436) | 1.94546242 |
87 | Hepatocellular necrosis (HP:0001404) | 1.90596889 |
88 | Fatigable weakness (HP:0003473) | 1.89935677 |
89 | Abnormality of the neuromuscular junction (HP:0003398) | 1.89935677 |
90 | Type 2 muscle fiber atrophy (HP:0003554) | 1.88679087 |
91 | Ketoacidosis (HP:0001993) | 1.87335674 |
92 | Mitochondrial inheritance (HP:0001427) | 1.87317453 |
93 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.87133803 |
94 | Foot dorsiflexor weakness (HP:0009027) | 1.86565826 |
95 | Bulbar palsy (HP:0001283) | 1.85524395 |
96 | Increased muscle lipid content (HP:0009058) | 1.85122777 |
97 | Slender build (HP:0001533) | 1.82681410 |
98 | Limb-girdle muscle weakness (HP:0003325) | 1.81691338 |
99 | Abnormality of the calcaneus (HP:0008364) | 1.80794271 |
100 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.79254313 |
101 | Increased CSF lactate (HP:0002490) | 1.79108702 |
102 | Hip contracture (HP:0003273) | 1.78448212 |
103 | Metatarsus adductus (HP:0001840) | 1.77947520 |
104 | Long clavicles (HP:0000890) | 1.75657685 |
105 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.75368681 |
106 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.75368681 |
107 | Weak cry (HP:0001612) | 1.74869668 |
108 | Abnormality of the ischium (HP:0003174) | 1.74221779 |
109 | Lower limb amyotrophy (HP:0007210) | 1.72425051 |
110 | Muscle fiber atrophy (HP:0100295) | 1.69139749 |
111 | Nonprogressive disorder (HP:0003680) | 1.65954724 |
112 | Increased intramyocellular lipid droplets (HP:0012240) | 1.61539518 |
113 | Limited hip movement (HP:0008800) | 1.53661530 |
114 | Shoulder girdle muscle weakness (HP:0003547) | 1.52697691 |
115 | Pelvic girdle muscle weakness (HP:0003749) | 1.52653093 |
116 | Ulnar deviation of finger (HP:0009465) | 1.51762462 |
117 | Abnormality of placental membranes (HP:0011409) | 1.50581558 |
118 | Amniotic constriction ring (HP:0009775) | 1.50581558 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 8.40531896 |
2 | TTN | 6.28798085 |
3 | PHKG2 | 4.48357750 |
4 | PHKG1 | 4.48357750 |
5 | PDK4 | 2.87731573 |
6 | PDK3 | 2.87731573 |
7 | NEK1 | 2.60364243 |
8 | DMPK | 2.55643756 |
9 | PIK3CG | 2.45922764 |
10 | NME1 | 2.41295664 |
11 | MYLK | 2.29558874 |
12 | TRIB3 | 2.21000932 |
13 | PKN2 | 2.20156456 |
14 | PIK3CA | 2.09350070 |
15 | STK24 | 2.05914560 |
16 | BCKDK | 2.00509444 |
17 | PINK1 | 1.91454876 |
18 | MAP2K3 | 1.90908933 |
19 | PDK2 | 1.76752206 |
20 | MUSK | 1.76221222 |
21 | LMTK2 | 1.67305316 |
22 | MAP3K7 | 1.58206087 |
23 | MAPK12 | 1.31638432 |
24 | ZAK | 1.20582809 |
25 | TIE1 | 1.17569544 |
26 | MARK1 | 1.16111915 |
27 | MAP3K3 | 1.12881105 |
28 | MAPKAPK3 | 1.10792195 |
29 | CCNB1 | 1.05114477 |
30 | STK38L | 1.03725764 |
31 | ILK | 1.02412197 |
32 | TRPM7 | 0.93552258 |
33 | MOS | 0.81860578 |
34 | PRKAA1 | 0.80317738 |
35 | PRKAA2 | 0.76766053 |
36 | PRKD1 | 0.76044270 |
37 | EEF2K | 0.75371098 |
38 | MAP2K6 | 0.73337501 |
39 | MAP2K4 | 0.72148737 |
40 | MAP3K13 | 0.71308794 |
41 | ROCK1 | 0.68930648 |
42 | RIPK1 | 0.67396991 |
43 | CAMK2D | 0.66559301 |
44 | DYRK1B | 0.65456003 |
45 | LIMK1 | 0.62979499 |
46 | CDC42BPA | 0.62779827 |
47 | MAP3K5 | 0.62096106 |
48 | PAK3 | 0.60356397 |
49 | GRK7 | 0.59830533 |
50 | FLT3 | 0.56873412 |
51 | NEK9 | 0.55302249 |
52 | AKT2 | 0.54222919 |
53 | PKN1 | 0.50198659 |
54 | CAMK2B | 0.47053917 |
55 | MAP3K11 | 0.46501593 |
56 | CAMK2G | 0.46066860 |
57 | INSRR | 0.45457086 |
58 | MAP2K1 | 0.43510773 |
59 | SGK3 | 0.40092191 |
60 | MAPK11 | 0.39918698 |
61 | PRKACB | 0.38956914 |
62 | STK4 | 0.38052437 |
63 | DAPK3 | 0.37738114 |
64 | TAOK2 | 0.36767535 |
65 | LATS1 | 0.35369257 |
66 | SGK2 | 0.34969540 |
67 | EPHB1 | 0.34592829 |
68 | STK38 | 0.34578649 |
69 | TGFBR2 | 0.34119515 |
70 | MAPK13 | 0.33999561 |
71 | ROCK2 | 0.33562663 |
72 | NME2 | 0.32827250 |
73 | CAMK4 | 0.32723292 |
74 | TAOK1 | 0.32711777 |
75 | NLK | 0.32222134 |
76 | WNK4 | 0.30879684 |
77 | PRKACA | 0.29965203 |
78 | DAPK2 | 0.29419588 |
79 | CAMK2A | 0.28652547 |
80 | KSR2 | 0.27841706 |
81 | EPHA3 | 0.26148536 |
82 | PRKD3 | 0.25641208 |
83 | ICK | 0.25591232 |
84 | PTK2B | 0.25454038 |
85 | PDGFRA | 0.25254790 |
86 | PTK6 | 0.24145569 |
87 | KDR | 0.23985389 |
88 | PRKG1 | 0.23124016 |
89 | CAMK1 | 0.23075661 |
90 | RPS6KL1 | 0.22707188 |
91 | RPS6KC1 | 0.22707188 |
92 | MAP3K10 | 0.22342028 |
93 | MAPK10 | 0.22036302 |
94 | TBK1 | 0.21478396 |
95 | RPS6KB1 | 0.20042298 |
96 | BMPR1B | 0.20027088 |
97 | PRKACG | 0.19071546 |
98 | FRK | 0.18905484 |
99 | LATS2 | 0.18617796 |
100 | MAP3K6 | 0.18359711 |
101 | PDPK1 | 0.17887665 |
102 | SGK1 | 0.17849699 |
103 | RPS6KA1 | 0.17270125 |
104 | WNK1 | 0.17062772 |
105 | LRRK2 | 0.16870400 |
106 | ARAF | 0.16661642 |
107 | RPS6KA6 | 0.16458169 |
108 | SIK1 | 0.15774546 |
109 | MAPK7 | 0.15769403 |
110 | STK11 | 0.14862746 |
111 | PDK1 | 0.14191122 |
112 | RPS6KA3 | 0.13671121 |
113 | FER | 0.13097522 |
114 | MARK3 | 0.13096085 |
115 | SGK494 | 0.12325867 |
116 | SGK223 | 0.12325867 |
117 | MAP3K1 | 0.10742121 |
118 | FGFR1 | 0.10440012 |
119 | RPS6KB2 | 0.10258813 |
120 | ERBB3 | 0.08321143 |
121 | MTOR | 0.07778496 |
122 | FGFR3 | 0.07751476 |
123 | RAF1 | 0.07689241 |
124 | MAPKAPK2 | 0.07182258 |
125 | PRKCH | 0.07010160 |
126 | MARK2 | 0.06606620 |
127 | TNIK | 0.06480348 |
128 | BRSK2 | 0.06349493 |
129 | MAPK4 | 0.05820823 |
130 | EPHB2 | 0.04952240 |
131 | PRKCA | 0.01368228 |
132 | MAPK9 | 0.01009712 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 5.82201777 |
2 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 4.69218025 |
3 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 4.15111581 |
4 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 4.05604315 |
5 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.81793529 |
6 | Parkinsons disease_Homo sapiens_hsa05012 | 3.37177470 |
7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.19494043 |
8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.90359561 |
9 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.89797294 |
10 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.74053726 |
11 | Carbon metabolism_Homo sapiens_hsa01200 | 2.59863006 |
12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.54257784 |
13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.29387817 |
14 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.26942740 |
15 | Huntingtons disease_Homo sapiens_hsa05016 | 2.06206147 |
16 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.89054769 |
17 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.84444016 |
18 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.82434258 |
19 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.74540567 |
20 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.65808347 |
21 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.63433837 |
22 | Viral myocarditis_Homo sapiens_hsa05416 | 1.60403763 |
23 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.48711452 |
24 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.41120554 |
25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.40661114 |
26 | Insulin resistance_Homo sapiens_hsa04931 | 1.32452865 |
27 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.24686519 |
28 | Galactose metabolism_Homo sapiens_hsa00052 | 1.12630779 |
29 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.08207418 |
30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.05525369 |
31 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.05428442 |
32 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.04484117 |
33 | Tight junction_Homo sapiens_hsa04530 | 0.97799192 |
34 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.95116205 |
35 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.93615059 |
36 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.92090557 |
37 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.89509156 |
38 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.89391662 |
39 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.87515827 |
40 | Focal adhesion_Homo sapiens_hsa04510 | 0.82335093 |
41 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.79967168 |
42 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.76519867 |
43 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.76024398 |
44 | Circadian rhythm_Homo sapiens_hsa04710 | 0.75460755 |
45 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.75352267 |
46 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73590802 |
47 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.73335439 |
48 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.73304168 |
49 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.73182460 |
50 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.70816262 |
51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.61364863 |
52 | Long-term potentiation_Homo sapiens_hsa04720 | 0.58173371 |
53 | Salivary secretion_Homo sapiens_hsa04970 | 0.56253115 |
54 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.55899839 |
55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.50025395 |
56 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.49134685 |
57 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.49050761 |
58 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.41268995 |
59 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.40742298 |
60 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.40369841 |
61 | Adherens junction_Homo sapiens_hsa04520 | 0.39710820 |
62 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.39413595 |
63 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.38309510 |
64 | Lysine degradation_Homo sapiens_hsa00310 | 0.37318747 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.36856654 |
66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.36702838 |
67 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.34970645 |
68 | Renin secretion_Homo sapiens_hsa04924 | 0.33950443 |
69 | Peroxisome_Homo sapiens_hsa04146 | 0.33364842 |
70 | Long-term depression_Homo sapiens_hsa04730 | 0.32467784 |
71 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.31791172 |
72 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.29783506 |
73 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.29048427 |
74 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.28919667 |
75 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.28239767 |
76 | Amoebiasis_Homo sapiens_hsa05146 | 0.27771948 |
77 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.27004788 |
78 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.26801689 |
79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.26380228 |
80 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.26206218 |
81 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.25270453 |
82 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.25089066 |
83 | Histidine metabolism_Homo sapiens_hsa00340 | 0.23618515 |
84 | Olfactory transduction_Homo sapiens_hsa04740 | 0.23517677 |
85 | Phototransduction_Homo sapiens_hsa04744 | 0.22541253 |
86 | Insulin secretion_Homo sapiens_hsa04911 | 0.21566727 |
87 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.21140281 |
88 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.20809099 |
89 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.18716907 |
90 | Platelet activation_Homo sapiens_hsa04611 | 0.18032385 |
91 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.17712921 |
92 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.16876771 |
93 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.16321617 |
94 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.14355931 |
95 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.13739894 |
96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.13670321 |
97 | ABC transporters_Homo sapiens_hsa02010 | 0.13335235 |
98 | Sulfur relay system_Homo sapiens_hsa04122 | 0.13147938 |
99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.12846639 |
100 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.12669342 |
101 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.11282624 |
102 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.06986530 |
103 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.04924076 |
104 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.02666102 |
105 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.01784181 |
106 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.01413597 |
107 | Circadian entrainment_Homo sapiens_hsa04713 | 0.00641612 |
108 | Bile secretion_Homo sapiens_hsa04976 | -0.0894911 |
109 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0850832 |
110 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | -0.0818976 |
111 | Purine metabolism_Homo sapiens_hsa00230 | -0.0794588 |
112 | Notch signaling pathway_Homo sapiens_hsa04330 | -0.0779835 |
113 | Cholinergic synapse_Homo sapiens_hsa04725 | -0.0566545 |
114 | Basal cell carcinoma_Homo sapiens_hsa05217 | -0.0497103 |
115 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | -0.0478105 |
116 | Gap junction_Homo sapiens_hsa04540 | -0.0454140 |
117 | Melanogenesis_Homo sapiens_hsa04916 | -0.0310716 |
118 | Toxoplasmosis_Homo sapiens_hsa05145 | -0.0076236 |