AQR

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.57323391
2nuclear pore organization (GO:0006999)5.54207538
3DNA unwinding involved in DNA replication (GO:0006268)4.76622341
4double-strand break repair via nonhomologous end joining (GO:0006303)4.50067578
5non-recombinational repair (GO:0000726)4.50067578
6protein localization to kinetochore (GO:0034501)4.42673186
7DNA double-strand break processing (GO:0000729)4.28861161
8pore complex assembly (GO:0046931)4.28406790
9replication fork processing (GO:0031297)4.25344151
10mitotic nuclear envelope disassembly (GO:0007077)4.24614589
11establishment of integrated proviral latency (GO:0075713)4.17641741
12negative regulation of DNA-dependent DNA replication (GO:2000104)4.12034461
13IMP biosynthetic process (GO:0006188)4.10969149
14folic acid-containing compound biosynthetic process (GO:0009396)4.08805784
15mitotic sister chromatid cohesion (GO:0007064)4.01757325
16somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.95109810
17somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.95109810
18isotype switching (GO:0045190)3.95109810
19regulation of histone H3-K9 methylation (GO:0051570)3.94249563
20membrane disassembly (GO:0030397)3.93648473
21nuclear envelope disassembly (GO:0051081)3.93648473
22negative regulation of histone methylation (GO:0031061)3.89857506
23pre-miRNA processing (GO:0031054)3.89543175
24synapsis (GO:0007129)3.88056502
25DNA duplex unwinding (GO:0032508)3.87843744
26DNA geometric change (GO:0032392)3.86779385
27DNA replication initiation (GO:0006270)3.83309711
28DNA replication-dependent nucleosome assembly (GO:0006335)3.72683662
29DNA replication-dependent nucleosome organization (GO:0034723)3.72683662
30protein localization to chromosome, centromeric region (GO:0071459)3.71874283
31somatic recombination of immunoglobulin gene segments (GO:0016447)3.67911222
32histone exchange (GO:0043486)3.61692395
33sister chromatid segregation (GO:0000819)3.60185827
34maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.57813026
35mitotic metaphase plate congression (GO:0007080)3.57462509
36nucleobase biosynthetic process (GO:0046112)3.56286161
37mitotic sister chromatid segregation (GO:0000070)3.55568593
38regulation of centrosome duplication (GO:0010824)3.53927218
39regulation of helicase activity (GO:0051095)3.53795903
40monoubiquitinated protein deubiquitination (GO:0035520)3.53535401
41IMP metabolic process (GO:0046040)3.53337347
42resolution of meiotic recombination intermediates (GO:0000712)3.52507146
43DNA strand elongation involved in DNA replication (GO:0006271)3.52448021
44mitotic chromosome condensation (GO:0007076)3.49391679
45sister chromatid cohesion (GO:0007062)3.49073905
46regulation of posttranscriptional gene silencing (GO:0060147)3.48244041
47regulation of gene silencing by miRNA (GO:0060964)3.48244041
48regulation of gene silencing by RNA (GO:0060966)3.48244041
49DNA ligation (GO:0006266)3.46685076
50somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.43438778
51somatic cell DNA recombination (GO:0016444)3.43438778
52regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.42328810
53regulation of mitotic spindle checkpoint (GO:1903504)3.42328810
54heterochromatin organization (GO:0070828)3.41045260
55response to X-ray (GO:0010165)3.40158522
56metaphase plate congression (GO:0051310)3.39148262
57regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.39109825
58DNA strand elongation (GO:0022616)3.38736723
59somatic diversification of immunoglobulins (GO:0016445)3.38684312
60regulation of spindle organization (GO:0090224)3.38221630
61regulation of RNA export from nucleus (GO:0046831)3.37208751
62positive regulation of chromosome segregation (GO:0051984)3.35387081
63regulation of sister chromatid segregation (GO:0033045)3.33903662
64regulation of mitotic sister chromatid separation (GO:0010965)3.33903662
65regulation of mitotic sister chromatid segregation (GO:0033047)3.33903662
66negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.27981232
67kinetochore organization (GO:0051383)3.26737085
68regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.26366276
69regulation of mitotic spindle organization (GO:0060236)3.25583284
70positive regulation of histone H3-K4 methylation (GO:0051571)3.25109672
71DNA replication checkpoint (GO:0000076)3.25047034
72somatic diversification of immune receptors (GO:0002200)3.24369824
73centriole replication (GO:0007099)3.23647094
74negative regulation of DNA recombination (GO:0045910)3.22835976
75somatic hypermutation of immunoglobulin genes (GO:0016446)3.22723440
76somatic diversification of immune receptors via somatic mutation (GO:0002566)3.22723440
77regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.21640438
78telomere maintenance via telomerase (GO:0007004)3.16783260
79regulation of chromatin silencing (GO:0031935)3.14871376
80positive regulation of mitotic sister chromatid separation (GO:1901970)3.14768214
81positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.14768214
82positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.14768214
83negative regulation of translation, ncRNA-mediated (GO:0040033)3.12507502
84regulation of translation, ncRNA-mediated (GO:0045974)3.12507502
85negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.12507502
86postreplication repair (GO:0006301)3.10084704
87histone H2A monoubiquitination (GO:0035518)3.10008897
88regulation of sister chromatid cohesion (GO:0007063)3.09548244
89telomere maintenance via semi-conservative replication (GO:0032201)3.09074421
90DNA conformation change (GO:0071103)3.08956390
91protein localization to chromosome (GO:0034502)3.08157819
92chromatin assembly (GO:0031497)3.08094759
93telomere maintenance (GO:0000723)3.07900721
94chromatin remodeling at centromere (GO:0031055)3.06230113
95establishment of chromosome localization (GO:0051303)3.04763597
96formation of translation preinitiation complex (GO:0001731)3.04709532
97purine nucleobase biosynthetic process (GO:0009113)3.04589690
98negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.04279978
99regulation of translational fidelity (GO:0006450)3.03994621
100telomere organization (GO:0032200)3.03799729
101maturation of 5.8S rRNA (GO:0000460)3.03179230
102RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.02771875
103translesion synthesis (GO:0019985)3.02679050
104dosage compensation (GO:0007549)3.02001098
105DNA replication-independent nucleosome assembly (GO:0006336)3.01810364
106DNA replication-independent nucleosome organization (GO:0034724)3.01810364
107nuclear envelope organization (GO:0006998)3.00804021
108mitotic spindle assembly checkpoint (GO:0007094)3.00639538
109DNA catabolic process, exonucleolytic (GO:0000738)3.00162993
110meiotic chromosome segregation (GO:0045132)2.99940555
111chromatin assembly or disassembly (GO:0006333)2.95911151
112CENP-A containing nucleosome assembly (GO:0034080)2.95742345
113mitotic recombination (GO:0006312)2.94034229
114maturation of SSU-rRNA (GO:0030490)2.90750401
115spliceosomal tri-snRNP complex assembly (GO:0000244)2.90046344
116regulation of DNA endoreduplication (GO:0032875)2.88877805
117intra-S DNA damage checkpoint (GO:0031573)2.88514011
118telomere maintenance via recombination (GO:0000722)2.88195990
119attachment of spindle microtubules to kinetochore (GO:0008608)2.86870201
120regulation of chromosome segregation (GO:0051983)2.86021064
121mRNA transport (GO:0051028)2.85437638
122negative regulation of RNA splicing (GO:0033119)2.84215244
123DNA topological change (GO:0006265)2.83300299
124mismatch repair (GO:0006298)2.81589504
125regulation of telomere maintenance via telomerase (GO:0032210)2.79626666
126regulation of centrosome cycle (GO:0046605)2.78660340
127negative regulation of chromosome segregation (GO:0051985)2.78396945
128regulation of centriole replication (GO:0046599)2.77414375
129spindle checkpoint (GO:0031577)2.76270233
130spindle assembly checkpoint (GO:0071173)2.75437348
131protein K6-linked ubiquitination (GO:0085020)2.75058136
132regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.74975472
133ATP-dependent chromatin remodeling (GO:0043044)2.74640796
134regulation of mitotic metaphase/anaphase transition (GO:0030071)2.74372655
135regulation of gene silencing (GO:0060968)2.73058452
136ribosome assembly (GO:0042255)2.72994995
137telomere maintenance via telomere lengthening (GO:0010833)2.72709781
138ribosome biogenesis (GO:0042254)2.71616129
139snRNA processing (GO:0016180)2.71466741
140negative regulation of mitotic sister chromatid separation (GO:2000816)2.71407155
141negative regulation of mitotic sister chromatid segregation (GO:0033048)2.71407155
142negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.71407155
143negative regulation of sister chromatid segregation (GO:0033046)2.71407155
144mitotic spindle checkpoint (GO:0071174)2.71272488
145RNA stabilization (GO:0043489)2.70012875

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.10501471
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.06687843
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.58013649
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.57995874
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.16773555
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.67623442
7* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.63036223
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.61815104
9MYC_22102868_ChIP-Seq_BL_Human2.48330216
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.37825400
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.23472388
12* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.15164597
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.12207940
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.11839195
15FUS_26573619_Chip-Seq_HEK293_Human2.10883076
16EWS_26573619_Chip-Seq_HEK293_Human2.04052154
17AR_21909140_ChIP-Seq_LNCAP_Human2.01782828
18ZNF274_21170338_ChIP-Seq_K562_Hela2.01331147
19E2F7_22180533_ChIP-Seq_HELA_Human10.3432772
20* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.97049762
21CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.90712869
22EST1_17652178_ChIP-ChIP_JURKAT_Human1.89616538
23CIITA_25753668_ChIP-Seq_RAJI_Human1.89470912
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89437338
25XRN2_22483619_ChIP-Seq_HELA_Human1.88222702
26BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.86955787
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.83068917
28FLI1_27457419_Chip-Seq_LIVER_Mouse1.82543114
29TP63_19390658_ChIP-ChIP_HaCaT_Human1.76934847
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73528328
31NANOG_18555785_ChIP-Seq_MESCs_Mouse1.69405425
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68111656
33NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.67393673
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67009939
35SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.65766029
36* VDR_23849224_ChIP-Seq_CD4+_Human1.64861023
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.62782934
38* FOXP3_21729870_ChIP-Seq_TREG_Human1.61676557
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.60007376
40* ETS1_20019798_ChIP-Seq_JURKAT_Human1.56953503
41ELF1_17652178_ChIP-ChIP_JURKAT_Human1.53833596
42CREB1_15753290_ChIP-ChIP_HEK293T_Human1.53014775
43* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51087655
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50440223
45POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.48973759
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.48832122
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.47160346
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.45883933
49P300_19829295_ChIP-Seq_ESCs_Human1.43195851
50IGF1R_20145208_ChIP-Seq_DFB_Human1.43133093
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.42993107
52KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.42038468
53TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41681336
54TAF15_26573619_Chip-Seq_HEK293_Human1.40692619
55KDM5A_27292631_Chip-Seq_BREAST_Human1.39953659
56HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.39823981
57TTF2_22483619_ChIP-Seq_HELA_Human1.38073001
58FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.37242438
59ELK1_19687146_ChIP-ChIP_HELA_Human1.35245280
60* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.33359742
61PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32080032
62AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31823434
63TFEB_21752829_ChIP-Seq_HELA_Human1.31702673
64VDR_22108803_ChIP-Seq_LS180_Human1.31019209
65* GABP_17652178_ChIP-ChIP_JURKAT_Human1.30195701
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28784561
67ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27361889
68ZFP57_27257070_Chip-Seq_ESCs_Mouse1.26872905
69KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.26098469
70KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.26098469
71KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.26098469
72POU5F1_16153702_ChIP-ChIP_HESCs_Human1.25947650
73JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.25688089
74* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.24745824
75SOX2_18555785_ChIP-Seq_MESCs_Mouse1.24625213
76MYC_18940864_ChIP-ChIP_HL60_Human1.24521185
77* GABP_19822575_ChIP-Seq_HepG2_Human1.22723486
78VDR_21846776_ChIP-Seq_THP-1_Human1.22529221
79SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21679719
80STAT3_1855785_ChIP-Seq_MESCs_Mouse1.20202942
81CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.20000818
82NANOG_16153702_ChIP-ChIP_HESCs_Human1.19659549
83DCP1A_22483619_ChIP-Seq_HELA_Human1.19638865
84SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.19418699
85PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.19285314
86PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18617355
87FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.15452430
88NOTCH1_21737748_ChIP-Seq_TLL_Human1.15355514
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14315934
90CBP_20019798_ChIP-Seq_JUKART_Human1.14256158
91IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.14256158
92RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13767099
93KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12281894
94GBX2_23144817_ChIP-Seq_PC3_Human1.12225323
95CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11012344
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11007295
97EZH2_27294783_Chip-Seq_NPCs_Mouse1.10939143
98ER_23166858_ChIP-Seq_MCF-7_Human1.09265720
99SOX2_16153702_ChIP-ChIP_HESCs_Human1.06699450
100ESR1_15608294_ChIP-ChIP_MCF-7_Human1.06179351
101POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05698824
102THAP11_20581084_ChIP-Seq_MESCs_Mouse1.05613339
103SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05115496
104RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05055217
105MYB_26560356_Chip-Seq_TH2_Human1.04489795
106E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.04268445
107ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.04078566
108E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04024949
109MYB_26560356_Chip-Seq_TH1_Human1.03235910
110STAT3_23295773_ChIP-Seq_U87_Human1.03033716
111* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.01855554
112ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01805011
113UTX_26944678_Chip-Seq_JUKART_Human1.00498813
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.00075721
115TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00061221
116ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.99941821
117HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.99606275
118CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99402611
119STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.99371614
120CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99267860
121PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98883204
122NANOG_21062744_ChIP-ChIP_HESCs_Human0.98432823
123NFE2_27457419_Chip-Seq_LIVER_Mouse0.97860338
124SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.96522777
125SALL4_22934838_ChIP-ChIP_CD34+_Human0.96283733
126* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95740699
127TCF7_22412390_ChIP-Seq_EML_Mouse0.95467037
128DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95293620
129* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94413304
130FOXM1_26456572_ChIP-Seq_MCF-7_Human0.94391532
131* SPI1_23547873_ChIP-Seq_NB4_Human0.93564818
132GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92818681
133CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92789092
134MAF_26560356_Chip-Seq_TH1_Human0.92680210
135IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.92156574
136* TCF3_18692474_ChIP-Seq_MESCs_Mouse0.91806676
137SMAD4_21799915_ChIP-Seq_A2780_Human0.91697855
138DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.91397658
139IRF1_19129219_ChIP-ChIP_H3396_Human0.91161523
140KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90065209
141GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89103273
142UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89055661
143PKCTHETA_26484144_Chip-Seq_BREAST_Human0.87949382
144ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.87895970
145SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.87626209
146CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.87311708
147NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.87177210
148* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.86323876
149NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.86251095
150SMAD3_21741376_ChIP-Seq_EPCs_Human0.85556235
151SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85539062
152* NANOG_18555785_Chip-Seq_ESCs_Mouse0.85213045
153* E2F1_18555785_Chip-Seq_ESCs_Mouse0.85101537
154SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.84420765
155RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.84294153

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.20573049
2MP0003693_abnormal_embryo_hatching4.19711072
3MP0003111_abnormal_nucleus_morphology3.92385168
4MP0008057_abnormal_DNA_replication3.84078034
5MP0003077_abnormal_cell_cycle3.53724129
6MP0004957_abnormal_blastocyst_morpholog3.34779696
7MP0010352_gastrointestinal_tract_polyps3.00347248
8MP0008058_abnormal_DNA_repair2.97474814
9MP0008007_abnormal_cellular_replicative2.78741272
10MP0002396_abnormal_hematopoietic_system2.61021952
11MP0009697_abnormal_copulation2.51141246
12MP0002009_preneoplasia2.48915882
13MP0010307_abnormal_tumor_latency2.36511904
14MP0003718_maternal_effect2.29052878
15MP0000350_abnormal_cell_proliferation2.25183493
16MP0001730_embryonic_growth_arrest2.23552736
17MP0005076_abnormal_cell_differentiation2.16457987
18MP0008877_abnormal_DNA_methylation2.04322484
19MP0004808_abnormal_hematopoietic_stem1.88532481
20MP0003123_paternal_imprinting1.85020115
21MP0001672_abnormal_embryogenesis/_devel1.82630829
22MP0005380_embryogenesis_phenotype1.82630829
23MP0003763_abnormal_thymus_physiology1.81707566
24MP0002254_reproductive_system_inflammat1.75297777
25MP0008932_abnormal_embryonic_tissue1.74871962
26MP0010234_abnormal_vibrissa_follicle1.74714539
27MP0003890_abnormal_embryonic-extraembry1.68978716
28MP0004197_abnormal_fetal_growth/weight/1.68444095
29MP0003984_embryonic_growth_retardation1.68015346
30MP0002084_abnormal_developmental_patter1.67439566
31MP0002088_abnormal_embryonic_growth/wei1.65497037
32MP0000490_abnormal_crypts_of1.63932363
33MP0001697_abnormal_embryo_size1.62252051
34MP0002086_abnormal_extraembryonic_tissu1.58611255
35MP0002085_abnormal_embryonic_tissue1.58366050
36MP0003786_premature_aging1.56089768
37MP0002102_abnormal_ear_morphology1.55148511
38MP0002080_prenatal_lethality1.49958081
39MP0003121_genomic_imprinting1.47322277
40MP0000703_abnormal_thymus_morphology1.41457452
41MP0010678_abnormal_skin_adnexa1.39545256
42MP0003705_abnormal_hypodermis_morpholog1.33914048
43MP0002398_abnormal_bone_marrow1.32759805
44MP0002019_abnormal_tumor_incidence1.32400642
45MP0000313_abnormal_cell_death1.32031728
46MP0001293_anophthalmia1.31211674
47MP0000427_abnormal_hair_cycle1.30394069
48MP0003567_abnormal_fetal_cardiomyocyte1.26236031
49MP0002877_abnormal_melanocyte_morpholog1.22337122
50MP0000383_abnormal_hair_follicle1.22034823
51MP0009278_abnormal_bone_marrow1.19760579
52MP0001545_abnormal_hematopoietic_system1.19490941
53MP0005397_hematopoietic_system_phenotyp1.19490941
54MP0000537_abnormal_urethra_morphology1.19417068
55MP0001661_extended_life_span1.17866979
56MP0006072_abnormal_retinal_apoptosis1.17085109
57MP0003566_abnormal_cell_adhesion1.15973918
58MP0000569_abnormal_digit_pigmentation1.15544625
59MP0002722_abnormal_immune_system1.14795611
60MP0003950_abnormal_plasma_membrane1.11952027
61MP0000689_abnormal_spleen_morphology1.06447317
62MP0001984_abnormal_olfaction1.06413631
63MP0000372_irregular_coat_pigmentation1.06324080
64MP0009333_abnormal_splenocyte_physiolog1.04492484
65MP0001915_intracranial_hemorrhage1.03292570
66MP0005410_abnormal_fertilization0.98781882
67MP0005023_abnormal_wound_healing0.97859107
68MP0001849_ear_inflammation0.97614375
69MP0001800_abnormal_humoral_immune0.97073665
70MP0006035_abnormal_mitochondrial_morpho0.95244873
71MP0003300_gastrointestinal_ulcer0.94645159
72MP0009703_decreased_birth_body0.93596557
73MP0005395_other_phenotype0.93295807
74MP0000371_diluted_coat_color0.92455259
75MP0001119_abnormal_female_reproductive0.92350333
76MP0000653_abnormal_sex_gland0.92191950
77MP0002429_abnormal_blood_cell0.91457839
78MP0000858_altered_metastatic_potential0.91266490
79MP0000716_abnormal_immune_system0.90824963
80MP0002210_abnormal_sex_determination0.90300852
81MP0000428_abnormal_craniofacial_morphol0.90017697
82MP0009672_abnormal_birth_weight0.90006724
83MP0003119_abnormal_digestive_system0.86923523
84MP0005379_endocrine/exocrine_gland_phen0.85761246
85MP0003698_abnormal_male_reproductive0.85696209
86MP0005367_renal/urinary_system_phenotyp0.85337938
87MP0000516_abnormal_urinary_system0.85337938
88MP0010030_abnormal_orbit_morphology0.85075489
89MP0000358_abnormal_cell_content/0.85047563
90MP0000733_abnormal_muscle_development0.84980277
91MP0003221_abnormal_cardiomyocyte_apopto0.84953830
92MP0005621_abnormal_cell_physiology0.84257061
93MP0002092_abnormal_eye_morphology0.83908040
94MP0006292_abnormal_olfactory_placode0.81640219
95MP0002166_altered_tumor_susceptibility0.81010019
96MP0005075_abnormal_melanosome_morpholog0.80771462
97MP0006054_spinal_hemorrhage0.80115003
98MP0001835_abnormal_antigen_presentation0.79748257
99MP0001145_abnormal_male_reproductive0.79294684
100MP0002420_abnormal_adaptive_immunity0.79075896
101MP0005671_abnormal_response_to0.78915285
102MP0002452_abnormal_antigen_presenting0.78620743
103MP0002653_abnormal_ependyma_morphology0.78287721
104MP0004264_abnormal_extraembryonic_tissu0.77985588
105MP0002111_abnormal_tail_morphology0.77946628
106MP0001819_abnormal_immune_cell0.77834917
107MP0005171_absent_coat_pigmentation0.77821378
108MP0002075_abnormal_coat/hair_pigmentati0.77799810
109MP0002925_abnormal_cardiovascular_devel0.77448924
110MP0005384_cellular_phenotype0.77339462
111MP0005253_abnormal_eye_physiology0.77157115
112MP0002006_tumorigenesis0.76450063
113MP0003943_abnormal_hepatobiliary_system0.76027483
114MP0003787_abnormal_imprinting0.75946135
115MP0003937_abnormal_limbs/digits/tail_de0.75492097
116MP0000477_abnormal_intestine_morphology0.75398509
117MP0001286_abnormal_eye_development0.74681330
118MP0000647_abnormal_sebaceous_gland0.74167673
119MP0002405_respiratory_system_inflammati0.73922120
120MP0000432_abnormal_head_morphology0.73916830
121MP0003941_abnormal_skin_development0.73868470
122MP0003448_altered_tumor_morphology0.73509086
123MP0001873_stomach_inflammation0.73153471
124MP0005174_abnormal_tail_pigmentation0.72309907
125MP0009053_abnormal_anal_canal0.72186376
126MP0002697_abnormal_eye_size0.71614767
127MP0005220_abnormal_exocrine_pancreas0.69500753
128MP0000685_abnormal_immune_system0.69042680
129MP0001177_atelectasis0.69013296
130MP0010155_abnormal_intestine_physiology0.68806533
131MP0002233_abnormal_nose_morphology0.68437116
132MP0001188_hyperpigmentation0.67083861
133MP0008789_abnormal_olfactory_epithelium0.66743130
134MP0001929_abnormal_gametogenesis0.66141913
135MP0001529_abnormal_vocalization0.66091587
136MP0002938_white_spotting0.65899780
137MP0002163_abnormal_gland_morphology0.65069661
138MP0002751_abnormal_autonomic_nervous0.64889955
139MP0003935_abnormal_craniofacial_develop0.64845064
140MP0003806_abnormal_nucleotide_metabolis0.64509098
141MP0001485_abnormal_pinna_reflex0.62421800
142MP0005408_hypopigmentation0.61636825
143MP0003699_abnormal_female_reproductive0.60649454
144MP0002161_abnormal_fertility/fecundity0.56120077
145MP0003195_calcinosis0.54395149
146MP0004782_abnormal_surfactant_physiolog0.52632708

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.13646173
2Chromsome breakage (HP:0040012)3.75304222
3Medulloblastoma (HP:0002885)3.69646840
4Volvulus (HP:0002580)3.49955039
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.45303371
6Selective tooth agenesis (HP:0001592)3.24096211
7Nephroblastoma (Wilms tumor) (HP:0002667)3.21730742
8Agnosia (HP:0010524)3.16090871
9Birth length less than 3rd percentile (HP:0003561)3.11445388
10Embryonal renal neoplasm (HP:0011794)3.09884651
11Colon cancer (HP:0003003)3.08625398
12Abnormality of the fingertips (HP:0001211)3.07151506
13Abnormality of chromosome stability (HP:0003220)3.04571414
14Abnormality of the astrocytes (HP:0100707)3.03954158
15Astrocytoma (HP:0009592)3.03954158
16Papillary thyroid carcinoma (HP:0002895)2.80041349
17Ectopic kidney (HP:0000086)2.74879848
18Basal cell carcinoma (HP:0002671)2.71611523
19Abnormality of the labia minora (HP:0012880)2.71190321
20Deviation of the thumb (HP:0009603)2.70970004
21Neoplasm of the oral cavity (HP:0100649)2.70959430
22Increased nuchal translucency (HP:0010880)2.69235575
23Rhabdomyosarcoma (HP:0002859)2.66082546
24Proximal placement of thumb (HP:0009623)2.65277483
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.62326310
26Short 4th metacarpal (HP:0010044)2.60589557
27Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.60589557
28Glioma (HP:0009733)2.58523294
29Prominent nose (HP:0000448)2.56644766
30Amaurosis fugax (HP:0100576)2.55089098
31Myelodysplasia (HP:0002863)2.53208584
32Reticulocytopenia (HP:0001896)2.48129213
33Abnormality of the preputium (HP:0100587)2.47455409
34Meckel diverticulum (HP:0002245)2.46700311
35Abnormal number of incisors (HP:0011064)2.45575023
36Methylmalonic acidemia (HP:0002912)2.43110246
37Long eyelashes (HP:0000527)2.39209717
38Biliary tract neoplasm (HP:0100574)2.38439465
39Malignant gastrointestinal tract tumors (HP:0006749)2.37533872
40Gastrointestinal carcinoma (HP:0002672)2.37533872
41Thyroid carcinoma (HP:0002890)2.35958556
42Abnormality of the ileum (HP:0001549)2.35606596
43Abnormal lung lobation (HP:0002101)2.34518027
44Abnormality of abdominal situs (HP:0011620)2.33878679
45Abdominal situs inversus (HP:0003363)2.33878679
46Carpal bone hypoplasia (HP:0001498)2.27608917
47Skull defect (HP:0001362)2.27152269
48Neoplasm of the adrenal cortex (HP:0100641)2.27144608
49Patellar aplasia (HP:0006443)2.26401986
50Impulsivity (HP:0100710)2.26139743
51Pancreatic islet-cell hyperplasia (HP:0004510)2.26089818
52Degeneration of anterior horn cells (HP:0002398)2.24330558
53Abnormality of the anterior horn cell (HP:0006802)2.24330558
54Thyroiditis (HP:0100646)2.24030765
55Ovarian neoplasm (HP:0100615)2.21931146
56Neoplasm of striated muscle (HP:0009728)2.20488818
57High pitched voice (HP:0001620)2.19436822
5811 pairs of ribs (HP:0000878)2.18582681
59Absent thumb (HP:0009777)2.16198485
60Cafe-au-lait spot (HP:0000957)2.15384693
61Breast carcinoma (HP:0003002)2.14584920
62Cortical dysplasia (HP:0002539)2.14572727
63Abnormality of the carotid arteries (HP:0005344)2.13875207
64Missing ribs (HP:0000921)2.13787219
65Duodenal stenosis (HP:0100867)2.09800688
66Small intestinal stenosis (HP:0012848)2.09800688
67IgM deficiency (HP:0002850)2.08951690
68Aplasia/Hypoplasia of the patella (HP:0006498)2.08291686
69Tubulointerstitial nephritis (HP:0001970)2.06559963
70Abnormality of DNA repair (HP:0003254)2.06441203
71Abnormal biliary tract morphology (HP:0012440)2.05994688
72Intestinal atresia (HP:0011100)2.04433007
73Chronic hepatic failure (HP:0100626)2.03228481
74Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.03149065
75Neoplasm of the pancreas (HP:0002894)2.02414840
76Neoplasm of the small intestine (HP:0100833)2.02280096
77Cutis marmorata (HP:0000965)2.01901963
78Absent radius (HP:0003974)2.00694138
79Lymphoma (HP:0002665)1.99892038
80Combined immunodeficiency (HP:0005387)1.94831642
81Abnormality of vitamin B metabolism (HP:0004340)1.94649254
82Sloping forehead (HP:0000340)1.93495731
83Aqueductal stenosis (HP:0002410)1.92613387
84Clitoromegaly (HP:0000057)1.92480601
85T lymphocytopenia (HP:0005403)1.91593542
86Abnormality of the vitamin B12 metabolism (HP:0004341)1.91508675
87Arteriovenous malformation (HP:0100026)1.91459402
88Sandal gap (HP:0001852)1.91192944
89Supernumerary spleens (HP:0009799)1.90808656
90Duplicated collecting system (HP:0000081)1.89926694
91Abnormality of methionine metabolism (HP:0010901)1.89631764
92Bone marrow hypocellularity (HP:0005528)1.89032083
93Heterotopia (HP:0002282)1.88526988
94IgA deficiency (HP:0002720)1.88011895
95Tracheoesophageal fistula (HP:0002575)1.87418435
96Urethral obstruction (HP:0000796)1.86775580
97Acute myeloid leukemia (HP:0004808)1.86157469
98Aplasia/Hypoplasia of the sternum (HP:0006714)1.85952249
99Curly hair (HP:0002212)1.84700819
100Abnormality of the pons (HP:0007361)1.83791299
101Aplasia involving forearm bones (HP:0009822)1.83264281
102Absent forearm bone (HP:0003953)1.83264281
103Esophageal atresia (HP:0002032)1.82730799
104Supernumerary ribs (HP:0005815)1.82330830
105Atresia of the external auditory canal (HP:0000413)1.82164134
106Neoplasm of the adrenal gland (HP:0100631)1.82116335
107Hypoglycemic seizures (HP:0002173)1.81279123
108Pseudobulbar signs (HP:0002200)1.80919799
109Deep philtrum (HP:0002002)1.80238770
110Premature graying of hair (HP:0002216)1.79141992
111Abnormality of the duodenum (HP:0002246)1.79071645
112High anterior hairline (HP:0009890)1.78736156
113Breast hypoplasia (HP:0003187)1.77379225
114Hyperacusis (HP:0010780)1.76967937
115Abnormal spermatogenesis (HP:0008669)1.76965486
116Abnormality of chromosome segregation (HP:0002916)1.76931994
117Spastic diplegia (HP:0001264)1.76774802
118Anal stenosis (HP:0002025)1.75315789
119Cutaneous melanoma (HP:0012056)1.75006367
120Abnormality of T cell number (HP:0011839)1.74943298
121Supernumerary bones of the axial skeleton (HP:0009144)1.74837441
122Abnormality of aspartate family amino acid metabolism (HP:0010899)1.74571070
123Skin tags (HP:0010609)1.73621556
124Progressive inability to walk (HP:0002505)1.73439816
125Cellular immunodeficiency (HP:0005374)1.72880335
126Facial hemangioma (HP:0000329)1.72849940
127Small hand (HP:0200055)1.72717159
128Spinal muscular atrophy (HP:0007269)1.72413152
129Clubbing of toes (HP:0100760)1.71883952
130Abnormality of the 4th metacarpal (HP:0010012)1.71868829
131Uterine neoplasm (HP:0010784)1.71550819
132Squamous cell carcinoma (HP:0002860)1.70805887
133Truncal obesity (HP:0001956)1.69757815
134Hypoplastic labia majora (HP:0000059)1.69597535
135Thrombocytosis (HP:0001894)1.69088678
136Oral leukoplakia (HP:0002745)1.69088286
137Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.68363358
138Neoplasm of the colon (HP:0100273)1.68274067
139Freckling (HP:0001480)1.67685917
140Triphalangeal thumb (HP:0001199)1.67100332
141Choanal atresia (HP:0000453)1.66525295
142Severe combined immunodeficiency (HP:0004430)1.65968868
143Abnormal hair whorl (HP:0010721)1.65802795
144Cystic hygroma (HP:0000476)1.64747679
145Embryonal neoplasm (HP:0002898)1.63446616
146Gonadotropin excess (HP:0000837)1.61220209
147Pancreatic cysts (HP:0001737)1.59675562
148Sensory axonal neuropathy (HP:0003390)1.58867949
149Gaze-evoked nystagmus (HP:0000640)1.58696723
150Aplasia/hypoplasia of the humerus (HP:0006507)1.57807923
151Abnormality of the labia majora (HP:0012881)1.57086337
152Gastrointestinal atresia (HP:0002589)1.56798235
153Astigmatism (HP:0000483)1.54506708

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.48542496
2CDC74.36905881
3MST43.05056939
4FRK2.89903203
5BRD42.83063332
6EEF2K2.78981091
7WEE12.56042891
8NEK22.55003119
9TRIM282.48609270
10TSSK62.35912069
11PASK2.32703267
12STK102.29821028
13TTK2.27295426
14BUB12.12128372
15SRPK12.02302769
16NUAK12.01827355
17RPS6KB21.97831149
18MAP3K101.95528136
19ATR1.92693248
20MAP4K11.81650654
21PBK1.77620640
22PNCK1.69717322
23CDK41.67725905
24CDK71.66093206
25PKN21.65500486
26MKNK11.59378248
27WNK31.58932768
28TGFBR11.56715365
29CHEK11.56085274
30PLK11.54659830
31TAF11.49798329
32AURKB1.48383025
33ALK1.46594076
34BMPR1B1.44772892
35STK31.44712105
36TNIK1.43889311
37BRSK21.43434403
38STK38L1.42115088
39CDK61.40771046
40RPS6KA41.40064489
41MKNK21.36903024
42MAP3K81.35959274
43ERBB31.34923567
44FLT31.34231235
45PLK21.33950040
46BCR1.32293483
47PLK31.31282973
48EPHA21.26959987
49EIF2AK21.25890126
50STK41.23081754
51PIM11.21331685
52MAP3K41.18848644
53EIF2AK11.18413675
54FGFR21.16154906
55ATM1.16089156
56NEK11.14479237
57NLK1.13565413
58LATS11.11725553
59CHEK21.10741118
60MELK1.08916694
61CDK21.05409106
62ACVR1B1.04501274
63MTOR1.01244658
64JAK31.00761931
65PLK41.00719764
66SCYL21.00323267
67MAP3K120.99723184
68TXK0.98185502
69CDK90.98090450
70CAMK1G0.96748752
71YES10.94059082
72AKT30.90821279
73VRK10.87599116
74LRRK20.87266915
75PAK40.86774899
76DYRK30.83842223
77TIE10.82739953
78TLK10.81643384
79CAMK1D0.79629669
80PTK60.77225696
81BTK0.77188609
82CHUK0.76645305
83ITK0.76272142
84ZAP700.75825331
85CDK10.75776729
86OXSR10.74830730
87ZAK0.72707381
88FGFR10.72608190
89STK390.72536266
90BRSK10.70313038
91CSNK1G10.65773473
92CASK0.62642918
93MARK30.59223603
94PDK20.58366255
95TEC0.57091840
96CSNK2A20.56957724
97INSRR0.56683204
98CSNK1D0.56668769
99CDK30.56132159
100MAP2K30.55940058
101CLK10.54155221
102AURKA0.53995383
103TTN0.53912835
104TYK20.53370202
105EIF2AK30.52992311
106PRKDC0.52309827
107TESK20.52188182
108MAPK140.51786889
109MAP4K20.51657182
110FGFR30.49696193
111VRK20.48708410
112PDGFRA0.48481538
113STK240.48174385
114NEK60.47291923
115ERBB40.46684812
116FER0.46381989
117GRK60.44690165
118MAPK10.42122290
119CSNK1G20.41236604
120CSNK1A1L0.41211641
121RPS6KA50.40829515
122CSNK1E0.40321333
123PAK20.39859032
124RPS6KB10.39116696
125LCK0.39009661
126AKT10.38466998
127AKT20.37478849
128GSK3B0.36329364
129CDK80.35907908
130ICK0.35255812
131GRK10.34664842
132CSNK1G30.34270917
133RIPK10.34042255
134EGFR0.32996236
135PIK3CG0.32395172
136CSNK2A10.30505298
137FGFR40.30393633
138TRIB30.30288411
139HCK0.29857925
140CSF1R0.28932539
141PAK10.28551182
142PRKCE0.25259488

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.98055507
2Mismatch repair_Homo sapiens_hsa034303.72818260
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.26518338
4* Spliceosome_Homo sapiens_hsa030403.02176968
5RNA transport_Homo sapiens_hsa030132.95531904
6One carbon pool by folate_Homo sapiens_hsa006702.94656536
7Cell cycle_Homo sapiens_hsa041102.72918443
8Base excision repair_Homo sapiens_hsa034102.61432872
9Homologous recombination_Homo sapiens_hsa034402.46562790
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.45173601
11Protein export_Homo sapiens_hsa030602.42642305
12Nucleotide excision repair_Homo sapiens_hsa034202.29894358
13Non-homologous end-joining_Homo sapiens_hsa034502.28021051
14Fanconi anemia pathway_Homo sapiens_hsa034602.26790033
15mRNA surveillance pathway_Homo sapiens_hsa030152.17655386
16Propanoate metabolism_Homo sapiens_hsa006402.13008090
17RNA polymerase_Homo sapiens_hsa030201.99177681
18RNA degradation_Homo sapiens_hsa030181.81009327
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65817368
20p53 signaling pathway_Homo sapiens_hsa041151.65411952
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.59333316
22Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.57857574
23Basal transcription factors_Homo sapiens_hsa030221.50599964
24Ribosome_Homo sapiens_hsa030101.50219884
25Antigen processing and presentation_Homo sapiens_hsa046121.49444446
26Viral carcinogenesis_Homo sapiens_hsa052031.48281051
27Pyrimidine metabolism_Homo sapiens_hsa002401.42685319
28Herpes simplex infection_Homo sapiens_hsa051681.40928370
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.38001567
30Systemic lupus erythematosus_Homo sapiens_hsa053221.35275369
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.32551891
32Epstein-Barr virus infection_Homo sapiens_hsa051691.30013567
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.26946618
34MicroRNAs in cancer_Homo sapiens_hsa052061.23313022
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.22901150
36Primary immunodeficiency_Homo sapiens_hsa053401.19469568
37HTLV-I infection_Homo sapiens_hsa051661.18098034
38NF-kappa B signaling pathway_Homo sapiens_hsa040641.16010655
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.12683725
40Small cell lung cancer_Homo sapiens_hsa052221.09101739
41Steroid biosynthesis_Homo sapiens_hsa001001.08403569
42Transcriptional misregulation in cancer_Homo sapiens_hsa052021.08224337
43Chronic myeloid leukemia_Homo sapiens_hsa052201.04133250
44Colorectal cancer_Homo sapiens_hsa052101.03568738
45Measles_Homo sapiens_hsa051621.02825673
46Notch signaling pathway_Homo sapiens_hsa043301.01262812
47Pyruvate metabolism_Homo sapiens_hsa006200.97961452
48Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.96718943
49Lysine degradation_Homo sapiens_hsa003100.93929728
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92728194
51Adherens junction_Homo sapiens_hsa045200.89552405
52Proteasome_Homo sapiens_hsa030500.86245774
53Basal cell carcinoma_Homo sapiens_hsa052170.83150126
54Hepatitis B_Homo sapiens_hsa051610.82601098
55Viral myocarditis_Homo sapiens_hsa054160.82153480
56Apoptosis_Homo sapiens_hsa042100.80260934
57Thyroid cancer_Homo sapiens_hsa052160.80183245
58Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.79534803
59Legionellosis_Homo sapiens_hsa051340.79466113
60Oocyte meiosis_Homo sapiens_hsa041140.77023442
61Selenocompound metabolism_Homo sapiens_hsa004500.76882825
62Hippo signaling pathway_Homo sapiens_hsa043900.76253405
63T cell receptor signaling pathway_Homo sapiens_hsa046600.75510553
64mTOR signaling pathway_Homo sapiens_hsa041500.71600953
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71545549
66Purine metabolism_Homo sapiens_hsa002300.70653469
67Influenza A_Homo sapiens_hsa051640.69249219
68B cell receptor signaling pathway_Homo sapiens_hsa046620.68046118
69Acute myeloid leukemia_Homo sapiens_hsa052210.67426249
70TGF-beta signaling pathway_Homo sapiens_hsa043500.66801342
71Leishmaniasis_Homo sapiens_hsa051400.64847740
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.64187892
73Hematopoietic cell lineage_Homo sapiens_hsa046400.63484640
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61980014
75Intestinal immune network for IgA production_Homo sapiens_hsa046720.61948029
76Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61872069
77Vitamin B6 metabolism_Homo sapiens_hsa007500.60076455
78Prostate cancer_Homo sapiens_hsa052150.59970318
79Endometrial cancer_Homo sapiens_hsa052130.59181454
80Pancreatic cancer_Homo sapiens_hsa052120.58626048
81Pathways in cancer_Homo sapiens_hsa052000.58599688
82Non-small cell lung cancer_Homo sapiens_hsa052230.58321423
83Regulation of autophagy_Homo sapiens_hsa041400.55960279
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55541822
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.55000780
86Butanoate metabolism_Homo sapiens_hsa006500.54679856
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.53884199
88Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53723620
89Jak-STAT signaling pathway_Homo sapiens_hsa046300.53429073
90Toxoplasmosis_Homo sapiens_hsa051450.52933495
91Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.52275536
92Inositol phosphate metabolism_Homo sapiens_hsa005620.51727750
93Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51466423
94Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.51315955
95Proteoglycans in cancer_Homo sapiens_hsa052050.48184794
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.47773129
97Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.46687520
98Alcoholism_Homo sapiens_hsa050340.46505832
99FoxO signaling pathway_Homo sapiens_hsa040680.45375669
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45015036
101HIF-1 signaling pathway_Homo sapiens_hsa040660.44127542
102Fatty acid biosynthesis_Homo sapiens_hsa000610.43848834
103Allograft rejection_Homo sapiens_hsa053300.43308011
104Osteoclast differentiation_Homo sapiens_hsa043800.43221697
105Biosynthesis of amino acids_Homo sapiens_hsa012300.41894072
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.41421984
107TNF signaling pathway_Homo sapiens_hsa046680.41065437
108Carbon metabolism_Homo sapiens_hsa012000.39862193
109Fatty acid metabolism_Homo sapiens_hsa012120.39798363
110Wnt signaling pathway_Homo sapiens_hsa043100.39471228
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39331888
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.39164443
113Circadian rhythm_Homo sapiens_hsa047100.38691616
114N-Glycan biosynthesis_Homo sapiens_hsa005100.37231150
115Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.36777361
116Shigellosis_Homo sapiens_hsa051310.36664899
117Pentose phosphate pathway_Homo sapiens_hsa000300.36252666
118Cyanoamino acid metabolism_Homo sapiens_hsa004600.36097251
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.33332246
120Tight junction_Homo sapiens_hsa045300.33204041
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33128069
122Hedgehog signaling pathway_Homo sapiens_hsa043400.31831400
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31258552
124Bladder cancer_Homo sapiens_hsa052190.30609449
125Phosphatidylinositol signaling system_Homo sapiens_hsa040700.29481957
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.27013814
127Hepatitis C_Homo sapiens_hsa051600.26294390
128Maturity onset diabetes of the young_Homo sapiens_hsa049500.26234846
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.26223058
130Caffeine metabolism_Homo sapiens_hsa002320.24072324
131Peroxisome_Homo sapiens_hsa041460.23379539
132Metabolic pathways_Homo sapiens_hsa011000.23209375
133Nitrogen metabolism_Homo sapiens_hsa009100.19690324
134Dorso-ventral axis formation_Homo sapiens_hsa043200.19644163
135Fatty acid elongation_Homo sapiens_hsa000620.19409013
136Primary bile acid biosynthesis_Homo sapiens_hsa001200.19065539
137Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18592560
138Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.18545472
139Taste transduction_Homo sapiens_hsa047420.17638893
140Tryptophan metabolism_Homo sapiens_hsa003800.17177713
141Phototransduction_Homo sapiens_hsa047440.14728299
142Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.13258824
143Fatty acid degradation_Homo sapiens_hsa000710.13032807
144beta-Alanine metabolism_Homo sapiens_hsa004100.12690289

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